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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Serum Uric Acid is Associated with Renal Prognosis of Lupus Nephritis in Women but not in Men | Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. Early intervention in lupus nephritis improves prognosis. There is an association between hyperuricemia and lupus nephritis; nevertheless, the sex-specific role of uric acid in lupus nephritis remains unclear. We retrospectively analyzed 578 patients diagnosed with LN by renal biopsy. We determine the relationship of serum uric acid to progression of LN using Kaplan-Meier survival analyses and Cox proportional hazards models. The primary end point was LN progression defined as the initiation of dialysis or kidney transplantation. Men had higher mean serum uric acid levels than did women. Every 1 mg/dL increase in baseline uric acid level increased the risk of LN progression by 15.1%. The serum uric acid level was an independent risk factor for LN progression in women (hazard ratio [HR], 1.158; confidence interval [CI], 1.018-1.317; p = 0.028) but not in men (HR, 1.499; CI, 0.964-2.331; p = 0.072). Sensitivity analysis involving serum uric acid terciles generated consistent and robust results. Serum uric acid level was an independent risk factor for LN progression in women but not in men. | Oh, Tae Ryom; Choi, Hong Sang; Kim, Chang Seong; Ryu, Dong-Ryeol; Park, Sun-Hee; Ahn, Shin Young; Kim, Soo Wan; Bae, Eun Hui; Ma, Seong Kwon | Chonnam Natl Univ, Dept Internal Med, Sch Med, Gwangju 61469, South Korea; Ewha Womans Univ, Dept Internal Med, Coll Med, Seoul Hosp, Seoul 07985, South Korea; Kyungpook Natl Univ, Div Nephrol, Dept Internal Med, Sch Med, Daegu 41944, South Korea; Korea Univ, Dept Internal Med, Coll Med, Seoul 02841, South Korea | Kim, Soon Hee/GXF-6736-2022; Park, Sun-Hee/LMN-0033-2024 | 57104451500; 37057121100; 55938725900; 56669926200; 7501831741; 55313081300; 56108124300; 56463618300; 7403725280 | tryeomoh@daum.net;hongsang38@hanmail.net;laminion@daum.net;drryu@ewha.ac.kr;sh-park@knu.ac.kr;ahnshinyoung712@gmail.com;skimw@chonnam.ac.kr;baedak76@gmail.com;drmsk@daum.net; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 9 | 3 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 4.242 | 23.1 | 0.56 | 2025-06-25 | 11 | 11 | lupus nephritis; hyperuricemia; uric acid; systemic lupus erythematosus; prognosis; proportional hazard models; end stage renal disease; sex | URATE TRANSPORTER; HYPERURICEMIA; PROGRESSION; SLC2A9; SEX; ERYTHEMATOSUS; IMPUTATION; DISEASE | End stage renal disease; Hyperuricemia; Lupus nephritis; Prognosis; Proportional hazard models; Sex; Systemic lupus erythematosus; Uric acid | anti double stranded antibody; antinuclear antibody; creatinine; hemoglobin; serum albumin; unclassified drug; uric acid; adult; anemia; Article; body mass; cholesterol blood level; controlled study; diastolic blood pressure; disease exacerbation; female; follow up; hazard ratio; human; hyperuricemia; Kaplan Meier method; kidney biopsy; kidney transplantation; lupus erythematosus nephritis; major clinical study; male; mass spectrometry; observational study; protein urine level; renal replacement therapy; retrospective study; risk factor; sensitivity analysis; systolic blood pressure | English | 2020 | 2020-03 | 10.3390/jcm9030773 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Therapeutic Effects of Human Mesenchymal Stem Cells in a Mouse Model of Cerebellar Ataxia with Neuroinflammation | Cerebellar ataxias (CAs) are neurological diseases characterized by loss of muscle coordination that is a result of damage and inflammation to the cerebellum. Despite considerable efforts in basic and clinical research, most CAs are currently incurable. In this study, we evaluated the therapeutic potential of human mesenchymal stem cells (hMSCs) against CAs associated with neuroinflammation. We observed that hMSC treatment significantly inhibited the symptoms of ataxia in lipopolysaccharide (LPS)-induced inflammatory CA (ICA) mice, which were recently reported as a potential animal model of ICA, through the anti-inflammatory effect of hMSC-derived TNF alpha-stimulated gene-6 (TSG-6), the protection of Purkinje cells by inhibition of apoptosis, and the modulatory effect for microglial M2 polarization. Thus, our results suggest that hMSC treatment may be an effective therapeutic approach for preventing or improving ataxia symptoms. | Nam, Youngpyo; Yoon, Dongyeong; Hong, Jungwan; Kim, Min Sung; Lee, Tae Yong; Kim, Kyung Suk; Lee, Ho-Won; Suk, Kyoungho; Kim, Sang Ryong | Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Life Sci, Plus KNU Creat BioRes Grp BK21, Daegu 41566, South Korea; Corestem Inc, Bioengn Inst, Seoul 13486, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurol, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Plus KNU Biomed Convergence Program BK21, Daegu 41944, South Korea | 55143100300; 57214744587; 57196247899; 57218438989; 57205775062; 59082232900; 35337240700; 7005114595; 56486163800 | blackpyo2@naver.com;ydy10@naver.com;jungwan33@naver.com;mskim@corestem.com;tylee@corestem.com;kskim@corestem.com;neuromd@knu.ac.kr;ksuk@knu.ac.kr;srk75@knu.ac.kr; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 9 | 11 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 4.242 | 23.1 | 0.4 | 2025-06-25 | 7 | 8 | cerebellar ataxia; neuroinflammation; microglia; mesenchymal stem cell; lipopolysaccharide | UMBILICAL-CORD BLOOD; BONE-MARROW; ADIPOSE-TISSUE; STROMAL CELLS; BRAIN; TSG-6; NEURONS; INJURY; TRANSPLANTATION; NEUROTOXICITY | Cerebellar ataxia; Lipopolysaccharide; Mesenchymal stem cell; Microglia; Neuroinflammation | lipopolysaccharide; pentraxin 3; animal cell; animal experiment; animal model; antiinflammatory activity; apoptosis; Article; cell migration; cerebellar ataxia; cisterna magna; controlled study; flow cytometry; human; human cell; male; mesenchymal stem cell; microglia; mouse; mouse model; nervous system inflammation; nonhuman; polarization; Purkinje cell; software; therapy effect; upregulation | English | 2020 | 2020-11 | 10.3390/jcm9113654 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Age-related differences in the associations among at-risk drinking, alcohol use disorder, and psychological distress across the adult lifespan: a nationwide representative study in South Korea | Purpose To investigate age-related differences in the relationships among at-risk alcohol consumption, alcohol use disorder (AUD), and psychological distress with a special focus on older adults. Methods We used a nationwide cross-sectional study of a representative sample of community-dwelling adults from the Korean Epidemiologic Catchment Area study for psychiatric disorders conducted by door-to-door interviews. The Korean version of the Composite International Diagnostic Interview was applied. Subjects were categorized into four age groups: young-to-middle-aged (20-54 years), near-old (55-64 years), early-old (65-74 years), and late-old (>= 75 years). The associations among at-risk drinking, alcohol use disorder, and psychological distress were examined according to age groups. Results Among a total of 5102 individuals, half of them drank alcohol in the previous year, of whom 20.5% were at-risk drinkers (>= 100 g/week). Older people were less often diagnosed with AUD than young-to-middle-aged adults with a similar degree of at-risk drinking. They were less likely to meet the DSM-5 AUD criteria in terms of social and vocational role disruption or creation of a physically hazardous situation. However, at-risk drinking showed a stronger association with subjective psychological distress in older adults, particularly in the near-old group (adjusted odds ratio 1.82, 95% confidence interval 1.09-3.03; p = 0.023). Conclusions These findings indicate the importance of screening for mental health problems in older adults, especially near-old adults, who drink more than 100 g of alcohol per week even when they do not satisfy the criteria for a diagnosis of AUD. | Park, Jee Eun; Hong, Jin Pyo; Jeon, Hong Jin; Seong, Su Jeong; Sohn, Jee Hoon; Ha, Tae Hyon; Lee, Dong-Woo; Park, Jong-Ik; Cho, Seong-Jin; Chang, Sung Man; Kim, Byung-Soo; Suk, Hye Won; Cho, Maeng Je; Hahm, Bong-Jin | Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Psychiat, Coll Med, 101 Daehak Ro, Seoul 110744, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Psychiat, Sch Med, Seoul, South Korea; Hallym Univ, Dept Psychiat, Med Ctr, Seoul, South Korea; Seoul Natl Univ, Dept Psychiat, Bundang Hosp, Sungnam, South Korea; Inje Univ, Dept Psychiat, Coll Med, Seoul, South Korea; Kangwon Natl Univ, Dept Psychiat, Coll Med, Chunchon, South Korea; Gachon Med Sch, Dept Psychiat, Incheon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu, South Korea; Sogang Univ, Dept Psychol, Seoul, South Korea | Hahm, Bong-Jin/J-5714-2012; Lee, Dong/H-2427-2012; Kim, Byung-Soo/H-4047-2013; Ha, Tae/U-5558-2019 | 56119414400; 55729426400; 35195917400; 55079714000; 35216092100; 7203014550; 56337476800; 15036290300; 55572091200; 23092756400; 57214661242; 35191238300; 57049717000; 6601908426 | hahm@snu.ac.kr; | SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY | SOC PSYCH PSYCH EPID | 0933-7954 | 1433-9285 | 55 | 10 | SCIE;SSCI | PSYCHIATRY | 2020 | 4.328 | 23.3 | 0.43 | 2025-06-25 | 6 | 6 | At-risk drinking; Alcohol use disorder; Psychological distress; DSM-IV; DSM-5 | SUBSTANCE-USE DISORDERS; OLDER-ADULTS; MENTAL-HEALTH; DSM-IV; CONSUMPTION; DEPENDENCE; THERMOMETER; PREVALENCE; CRITERIA; GENDER | Alcohol use disorder; At-risk drinking; DSM-5; DSM-IV; Psychological distress | Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Cross-Sectional Studies; Humans; Longevity; Middle Aged; Psychological Distress; Republic of Korea; Young Adult; adult; aged; alcoholism; cross-sectional study; distress syndrome; drinking behavior; human; longevity; middle aged; South Korea; very elderly; young adult | English | 2020 | 2020-10 | 10.1007/s00127-020-01845-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Gliome database: a comprehensive web-based tool to access and analyze glia secretome data | Glial cells are phenotypically heterogeneous non-neuronal components of the central and peripheral nervous systems. These cells are endowed with diverse functions and molecular machineries to detect and regulate neuronal or their own activities by various secreted mediators, such as proteinaceous factors. In particular, glia-secreted proteins form a basis of a complex network of glia-neuron or glia-glia interactions in health and diseases. In recent years, the analysis and profiling of glial secretomes have raised new expectations for the diagnosis and treatment of neurological disorders due to the vital role of glia in numerous physiological or pathological processes of the nervous system. However, there is no online database of glia-secreted proteins available to facilitate glial research. Here, we developed a user-friendly 'Gliome' database (available at www.gliome.org ), a web-based tool to access and analyze glia-secreted proteins. The database provides a vast collection of information on 3293 proteins that are released from glia of multiple species and have been reported to have differential functions under diverse experimental conditions. It contains a web-based interface with the following four key features regarding glia-secreted proteins: (i) fundamental information, such as signal peptide, SecretomeP value, functions and Gene Ontology category; (ii) differential expression patterns under distinct experimental conditions; (iii) disease association; and iv) interacting proteins. In conclusion, the Gliome database is a comprehensive webbased tool to access and analyze glia-secretome data obtained from diverse experimental settings, whereby it may facilitate the integration of bioinformatics into glial research. | Kim, Jong-Heon; Park, Su-Hyeong; Han, Jin; Ko, Pan-Woo; Kwon, Dongseop; Suk, Kyoungho | Kyungpook Natl Univ, Brain Sci & Engn Inst, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol, 680 Gukchaebosang Ro, Daegu 41944, South Korea; D&P BIOTECH, 807 Hoguk Ro, Daegu 41404, South Korea; Kyungpook Natl Univ, Dept Neurol, Chilgok Hosp, 807 Hoguk Ro, Daegu 41404, South Korea; Myongji Univ, Sch Software Convergence, 34 Geobukgol Ro, Seoul 03674, South Korea | 57203324811; 57218361426; 57218360938; 55543341200; 10143029100; 7005114595 | dongseop@mju.ac.kr;ksuk@knu.ac.kr; | DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION | DATABASE-OXFORD | 1758-0463 | SCIE | MATHEMATICAL & COMPUTATIONAL BIOLOGY | 2020 | 3.451 | 23.3 | 0.32 | 2025-06-25 | 4 | 7 | STEM-CELL SECRETOME; CEREBROSPINAL-FLUID; PROTEOME; BIOMARKERS; DISSECTION; SIGNATURE; PROTEINS; HEALTH | Animals; Databases, Protein; Humans; Internet; Neuroglia; Proteins; Software; protein; animal; chemistry; glia; human; Internet; metabolism; protein database; software | English | 2020 | 2020-07-31 | 10.1093/database/baaa057 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | A novel bifunctional Dy³⁺ activated RbCaF3 single phase phosphor: Facile synthesis and dual-luminescence properties for WLEDs and dosimetry applications | A series of Dy3+ activated RbCaF3 phosphors was synthesized by the conventional high temperature solid state reaction technique under ambient atmosphere. The structural properties and morphology of synthesized compounds were analyzed by PXRD and FE-SEM, respectively. The chemical composition of synthesized phosphors was obtained by EDAX. The phosphor was excited at 386 nm and monitored at 484 and 574 nm, and the strongest peak was located at 484 nm (blue region). In addition, the point of RbCaF3: Dy3+ with calculated chromaticity coordinates in the CIE diagram was located in the yellow region. TL characteristics of the RbCaF3:Dy3+ phosphor was analyzed and the glow curve peak was emitted at 355 K. The symmetry factor, Balarin parameter, activation energy and frequency factor were calculated by Chen method from the TL glow curve, and the TL signal degradation was also analyzed. (C) 2020 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved. | Raja, Arumugam; Nagaraj, R.; Ramachandran, K.; Sivasubramani, V; Annadurai, G.; Daniel, D. Joseph; Ramasamy, P. | Sri Sivasubramaniya Nadar Coll Engn, SSN Res Ctr, Kalavakkam 603110, Tamil Nadu, India; SRM Inst Sci & Technol, Dept Phys, Ramapuram Campus, Chennai 600089, Tamil Nadu, India; Taiyuan Univ Technol, Coll Phys & Optoelect, Key Lab Adv Transducers & Intelligent Control Sys, Minist Educ & Shanxi Prov, Taiyuan 030024, Peoples R China; Kyungpook Natl Univ, Inst High Energy & Nanophys, Dept Phys, Daegu 702701, South Korea | G, Annadurai/L-2055-2016; Raja, Arumugam/Q-1781-2019; Vediyappan, Sivasubramani/AAX-2668-2021; Ramasamy, Prakash/AGT-2329-2022; ramachandran, krithikadevi/ABC-3128-2020 | 57189505213; 57194397594; 57210226796; 57164895100; 56573829700; 55235066800; 36014318600 | rajaphy014@gmail.com; | ADVANCED POWDER TECHNOLOGY | ADV POWDER TECHNOL | 0921-8831 | 1568-5527 | 31 | 7 | SCIE | ENGINEERING, CHEMICAL | 2020 | 4.833 | 23.4 | 0.83 | 2025-06-25 | 13 | 14 | X-ray luminescence; Radiation dosimetry; WLED; Thermoluminescence; Phosphors | HYDROTHERMAL SYNTHESIS; THERMAL-PROPERTIES; CRYSTAL-GROWTH; NANOPARTICLES; KMNF3 | Phosphors; Radiation dosimetry; Thermoluminescence; WLED; X-ray luminescence | Activation energy; Calcium compounds; High temperature applications; Luminescence; Phosphors; Rubidium compounds; Solid state reactions; Ambient atmosphere; Chemical compositions; Chromaticity coordinates; Dual luminescence; Facile synthesis; Frequency factors; High temperature solid-state reaction; Signal degradation; Dysprosium compounds | English | 2020 | 2020-07 | 10.1016/j.apt.2020.04.025 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | BBR Advanced (BBR-A) - Reduced retransmissions with improved fairness | In 2016, Google proposed Bottleneck Bandwidth and Round-trip-time (BBR), a new TCP congestion control algorithm to avoid bottleneck queue formation and utilize underlying bandwidth in full. However, recent reports have found significant flaws in BBR, especially a high packet retransmissions problem, and throughput unfairness issue. We propose BBR Advanced (BBR-A) that resolves these issues by halving the congestion window and slowing down the pacing gain for actual congestion events, which it decides based on packet losses and RTT. Mininet emulation experiments confirm that BBR-A reduces retransmissions up to 60% and increases fairness index up to 10% in comparison with BBR. (C) 2020 The Korean Institute of Communications and Information Sciences (KICS). Publishing services by Elsevier B.V. | Mahmud, Imtiaz; Cho, You-Ze | Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | Mahmud, Imtiaz/R-1089-2019 | 56203487900; 7404469829 | yzcho@knu.ac.kr; | ICT EXPRESS | ICT EXPRESS | 2405-9595 | 6 | 4 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;TELECOMMUNICATIONS | 2020 | 4.317 | 23.6 | 0.3 | 2025-06-25 | 8 | 11 | BBR; Retransmissions; Fairness; TCP; Congestion control | BBR; Congestion control; Fairness; Retransmissions; TCP | English | 2020 | 2020-12 | 10.1016/j.icte.2020.05.009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Burnout Syndrome and Work-Related Stress in Physical and Occupational Therapists Working in Different Types of Hospitals: Which Group Is the Most Vulnerable? | Because of the nature of their work, physical and occupational therapists are at high risk of burnout, which is associated with decreased job satisfaction, medical errors, and mental wellbeing in healthcare professionals. To well manage and minimize potential impact of burnout, risk factors should be determined. This study examined burnout and job stress in physical and occupational therapists in various Korean hospital settings. Physical and occupational therapists from several rehabilitation facilities in South Korea completed a survey between March-May 2019. A set of questionnaires, including the Maslach Burnout Inventory and Job Content Questionnaire, were distributed to all participants. In total, 325 professionals (131 men and 194 women) were recruited. Burnout and work-related stress differed significantly according to several factors. Hospital size, gender, and age were the main contributory factors affecting at least two dimensions of the questionnaires. The more vulnerable group consisted of female therapists in their 20s at small- or medium-sized hospitals with low scores for quality of life. High levels of job stress and burnout were observed in female therapists in their 20s at small- or medium-sized hospitals. Hospitals and society should create suitable environments and understand the nature of therapists' work to improve healthcare. | Kim, Ju-Hyun; Kim, Ae-Ryoung; Kim, Myung-Gwan; Kim, Chul-Hyun; Lee, Ki-Hoon; Park, Donghwi; Hwang, Jong-Moon | Kyungpook Natl Univ Hosp, Dept Rehabil Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Rehabil Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Grad Sch Publ Hlth, Daegu 41566, South Korea; Mompyeonhan Rehabil Clin, Daegu 42401, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Phys Med & Rehabil, Coll Med, Ulsan 44033, South Korea | Park, Donghwi/GYQ-6185-2022 | 57208450909; 57196257330; 57217987383; 59603554500; 57218161131; 56606561400; 56367634000 | kjoohyun88@gmail.com;ryoung20@hanmail.net;curein@naver.com;chgim@knu.ac.kr;qu291@naver.com;bdome@hanmail.net;hti82@hanmail.net; | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | INT J ENV RES PUB HE | 1660-4601 | 17 | 14 | SCIE;SSCI | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.39 | 23.6 | 1.42 | 2025-06-25 | 50 | 44 | burnout syndrome; vulnerable group; physical therapist; occupational therapist; gender; hospital size; age | QUALITY-OF-LIFE; SATISFACTION | Age; Burnout syndrome; Gender; Hospital size; Occupational therapist; Physical therapist; Vulnerable group | Age Factors; Burnout, Professional; Burnout, Psychological; Child; Cross-Sectional Studies; Female; Health Facility Size; Humans; Job Satisfaction; Male; Occupational Stress; Occupational Therapists; Quality of Life; Republic of Korea; Sex Factors; Surveys and Questionnaires; Korea; health care; health worker; hospital sector; occupation; quality of life; risk factor; working conditions; adult; article; burnout; female; gender; human; job stress; major clinical study; male; Maslach Burnout Inventory; occupational therapist; physiotherapist; quality of life; questionnaire; rehabilitation; South Korea; age; burnout; child; cross-sectional study; epidemiology; health care facility; job satisfaction; job stress; occupational therapist; psychology; sex factor | English | 2020 | 2020-07 | 10.3390/ijerph17145001 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | D-LIA: Dynamic congestion control algorithm for MPTCP | The congestion control algorithm (CCA) of Multipath TCP (MPTCP) mainly portrays two fundamental challenges to properly utilize the available bandwidth. First, MPTCP should provide an incentive over single-path TCP while not harming any existing single-path TCP flows when sharing the same bottleneck. Second, it should better utilize the paths by ensuring high throughput with low packet losses. We focus to improve the second goal by implementing a novel technique to dynamically control the decrease factor of the CCA depending on the interval between packet losses. We implemented it in Linux kernel and found a significant performance improvement by extensive the Mininet experiments. (C) 2020 The Korean Institute of Communications and Information Sciences (KICS). Publishing services by Elsevier B.V. | Lubna, Tabassum; Mahmud, Imtiaz; Cho, You-Ze | Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | Mahmud, Imtiaz/R-1089-2019 | 57205303733; 56203487900; 7404469829 | juthy.cse@gmail.com;imtiaz.tee@gmail.com;yzcho@ee.knu.ac.kr; | ICT EXPRESS | ICT EXPRESS | 2405-9595 | 6 | 4 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;TELECOMMUNICATIONS | 2020 | 4.317 | 23.6 | 1.22 | 2025-06-25 | 19 | 27 | Congestion control; Dynamic decreasing mechanism; LIA; MPTCP | Congestion control; Dynamic decreasing mechanism; LIA; MPTCP | English | 2020 | 2020-12 | 10.1016/j.icte.2020.03.005 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Development of a Prediction Model for Demolition Waste Generation Using a Random Forest Algorithm Based on Small DataSets | Recently, artificial intelligence (AI) technologies have been employed to predict construction and demolition (C&D) waste generation. However, most studies have used machine learning models with continuous data input variables, applying algorithms, such as artificial neural networks, adaptive neuro-fuzzy inference systems, support vector machines, linear regression analysis, decision trees, and genetic algorithms. Therefore, machine learning algorithms may not perform as well when applied to categorical data. This article uses machine learning algorithms to predict C&D waste generation from a dataset, as a way to improve the accuracy of waste management in C&D facilities. These datasets include categorical (e.g., region, building structure, building use, wall material, and roofing material), and continuous data (particularly, gloss floor area), and a random forest (RF) algorithm was used. Results indicate that RF is an adequate machine learning algorithm for a small dataset consisting of categorical data, and even with a small dataset, an adequate prediction model can be developed. Despite the small dataset, the predictive performance according to the demolition waste (DW) type was R (Pearson's correlation coefficient) = 0.691-0.871, R-2 (coefficient of determination) = 0.554-0.800, showing stable prediction performance. High prediction performance was observed using three (for mortar), five (for other DW types), or six (for concrete) input variables. This study is significant because the proposed RF model can predict DW generation using a small amount of data. Additionally, it demonstrates the possibility of applying AI to multi-purpose DW management. | Cha, Gi-Wook; Moon, Hyeun Jun; Kim, Young-Min; Hong, Won-Hwa; Hwang, Jung-Ha; Park, Won-Jun; Kim, Young-Chan | Dankook Univ, Dept Architectural Engn, Yongin 16890, South Korea; Dankook Univ, Dept Appl Stat, Yongin 16890, South Korea; Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Architecture, Daegu 41566, South Korea; Kangwon Natl Univ, Dept Architectural Engn, Gangwon Do 25913, South Korea; Changshin Univ, Dept Fire & Disaster Prevent Engn, Gyeongsangnam Do 51352, South Korea | ; Kim, Young-Min/GON-3462-2022 | 55754413300; 24559146700; 57219216572; 7401527968; 55710714500; 55552256200; 56463201400 | cgwgnr@gmail.com;hmoon@dankook.ac.kr;dudals4051@gmail.com;hongwonhwa@gmail.com;peter@knu.ac.kr;wjpark@kangwon.ac.kr;yyoungchani@gmail.com; | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | INT J ENV RES PUB HE | 1660-4601 | 17 | 19 | SCIE;SSCI | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.39 | 23.6 | 2.02 | 2025-06-25 | 51 | 67 | demolition waste management; construction waste management; prediction model; random forest; leave-one-out cross-validation; small data | MULTIPLE LINEAR-REGRESSION; SUPPORT VECTOR MACHINE; CONSTRUCTION; PERFORMANCE; MANAGEMENT; CHINA | Construction waste management; Emolition waste management; Leave-one-out cross-validation; Prediction model; Random forest; Small data | Algorithms; Artificial Intelligence; Construction Industry; Machine Learning; Neural Networks, Computer; Solid Waste; Support Vector Machine; concrete; accuracy assessment; algorithm; artificial intelligence; construction; demolition; fuzzy mathematics; machine learning; waste management; accuracy; Article; comparative study; construction and demolition waste; correlation coefficient; data base; machine learning; mathematical analysis; mathematical computing; prediction; random forest; solid waste management; statistical model; validation process; algorithm; artificial intelligence; building industry; solid waste; support vector machine | English | 2020 | 2020-10 | 10.3390/ijerph17196997 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Emodin in Rheum undulatum inhibits oxidative stress in the liver via AMPK with Hippo/Yap signalling pathway | Context: Emodin is a compound in Rheum undulatum Linne (Polygonaceae) that has been reported to exert anti-inflammatory, antibacterial, and antiallergic effects. Objective: Oxidative stress is a causative agent of liver inflammation that may lead to fibrosis and hepato-carcinoma. In this study, we investigated the antioxidant effects of emodin and its mechanism. Materials and methods: We used the hepatocyte stimulated by arachidonic acid (AA) + iron cotreatment and the C57B/6 mice orally injected with acetaminophen (APAP, 500 mg/kg, 6 h), as assessed by immunoblot and next generation sequencing (NGS). Emodin was pre-treated in hepatocyte (3 similar to 30 mu M) for 1 h before AA + iron, and in mice (10 and 30 m/kg, P.O.) for 3 days before APAP. Results: In vitro, emodin treatment inhibited the cell death induced by AA + iron maximally at a dose of 10 mu M (EC50 > 3 mu M). In addition, emodin attenuated the decrease of anti-apoptotic proteins, and restored mitochondria membrane potential as mediated by the liver kinase B1 (LKB1)-AMP-activated protein kinase (AMPK) pathway. LKB1 mediated AMPK activation was verified using the LKB1 deficient cell line, HeLa. Emodin (10 mu M; after 10 min) also induced the phosphorylation of Yes-associated protein 1 (YAP1), the main downstream target of the Hippo signalling pathway that mediated oxidative stress or the ROS-initiated signalling pathway. In vivo, the oral treatment of emodin (10 and 30 m/kg, 3 days) decreased APAP-induced hepatic damage, as indicated by decreases in antioxidant genes as well as tissue damage. Conclusion: Our results show that emodin inhibits oxidative liver injury via the AMPK/YAP mediated pathway. | Lee, Eun Hye; Baek, Su Youn; Park, Ji Young; Kim, Young Woo | Kyungpook Natl Univ, Dept Biomed Sci, Daegu, South Korea; Kyungpook Natl Univ, Inst Phylogen & Evolut, Daegu, South Korea; Dongguk Univ, Sch Korean Med, Gyeongju 38066, South Korea | ; Lee, Eun-Hye/KDN-5679-2024 | 57189661699; 57192371420; 57210160197; 55699527800 | ywk@dongguk.ac.kr; | PHARMACEUTICAL BIOLOGY | PHARM BIOL | 1388-0209 | 1744-5116 | 58 | 1 | SCIE | MEDICAL LABORATORY TECHNOLOGY;PHARMACOLOGY & PHARMACY;PLANT SCIENCES | 2020 | 3.503 | 23.6 | 4.18 | 2025-06-25 | 52 | 53 | AMP-activated protein kinase; Yes-associated protein 1; liver kinase B1 | ARACHIDONIC-ACID; MITOCHONDRIAL DYSFUNCTION; HEPG2 CELLS; RNA-SEQ; ANTIOXIDANT; ACTIVATION; KINASE; DAMAGE; IRON; APOPTOSIS | AMP-activated protein kinase; liver kinase B1; Yes-associated protein 1 | Acetaminophen; Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Antioxidants; Cell Cycle Proteins; Cell Line, Tumor; Cells, Cultured; Chemical and Drug Induced Liver Injury; Eicosanoic Acids; Emodin; Gene Expression Regulation; Hepatocytes; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Oxidative Stress; Protein-Serine-Threonine Kinases; Reactive Oxygen Species; Rheum; Signal Transduction; adenylate kinase; arachidonic acid; emodin; reactive oxygen metabolite; transcription factor Yap1; antioxidant; arachidic acid; cell cycle protein; emodin; Hippo protein, mouse; hydroxymethylglutaryl coenzyme A reductase kinase; paracetamol; protein serine threonine kinase; signal transducing adaptor protein; Yap1 protein, mouse; AMPK signaling; animal experiment; animal model; animal tissue; antioxidant activity; Article; cell death; cell viability; controlled study; EC50; enzyme activation; gene; gene expression profiling; HeLa cell line; high throughput sequencing; hippo signaling; human; human cell; in vitro study; in vivo study; liver cell; liver injury; liver protection; male; mitochondrial membrane potential; mouse; nonhuman; oxidative stress; protein phosphorylation; Rheum; Rheum undulatum; treatment duration; Yap1 gene; animal; C57BL mouse; cell culture; chemistry; drug effect; gene expression regulation; metabolism; oxidative stress; signal transduction; toxic hepatitis; tumor cell line | English | 2020 | 2020-01-01 | 10.1080/13880209.2020.1750658 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Evaluating the Mutual Relationship between IPAT/Kaya Identity Index and ODIAC-Based GOSAT Fossil-Fuel CO2Flux: Potential and Constraints in Utilizing Decomposed Variables | The IPAT/Kaya identity is the most popular index used to analyze the driving forces of individual factors on CO(2)emissions. It represents the CO(2)emissions as a product of factors, such as the population, gross domestic product (GDP) per capita, energy intensity of the GDP, and carbon footprint of energy. In this study, we evaluated the mutual relationship of the factors of the IPAT/Kaya identity and their decomposed variables with the fossil-fuel CO(2)flux, as measured by the Greenhouse Gases Observing Satellite (GOSAT). We built two regression models to explain this flux; one using the IPAT/Kaya identity factors as the explanatory variables and the other one using their decomposed factors. The factors of the IPAT/Kaya identity have less explanatory power than their decomposed variables and comparably low correlation with the fossil-fuel CO(2)flux. However, the model using the decomposed variables shows significant multicollinearity. We performed a multivariate cluster analysis for further investigating the benefits of using the decomposed variables instead of the original factors. The results of the cluster analysis showed that except for the M factor, the IPAT/Kaya identity factors are inadequate for explaining the variations in the fossil-fuel CO(2)flux, whereas the decomposed variables produce reasonable clusters that can help identify the relevant drivers of this flux. | Hwang, YoungSeok; Um, Jung-Sup; Schlueter, Stephan | Kyungpook Natl Univ, Dept Climate Change, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Geog, Daegu 41566, South Korea; Ulm Univ Appl Sci, Dept Math Nat & Econ Sci, D-89075 Ulm, Germany | Um, Jung-Sup/F-5351-2018 | 57218585482; 35173565000; 55258366500 | poiu012345@naver.com;jsaeom@knu.ac.kr;stephan.schlueter@thu.de;schlueter@thu.de; | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | INT J ENV RES PUB HE | 1660-4601 | 17 | 16 | SCIE;SSCI | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.39 | 23.6 | 1.15 | 2025-06-25 | 17 | 20 | IPAT; Kaya identity; GOSAT; CO(2)flux; correlation; hierarchical cluster analysis | CO2 EMISSIONS; CARBON EMISSIONS; MITIGATION; COUNTRY; GROWTH | CO2 flux; Correlation; GOSAT; Hierarchical cluster analysis; IPAT/Kaya identity | Carbon Dioxide; Fossil Fuels; Greenhouse Gases; Gross Domestic Product; carbon dioxide; fossil fuel; carbon dioxide; carbon dioxide; carbon emission; carbon footprint; correlation; environmental economics; fossil fuel; fuel consumption; Gross Domestic Product; multivariate analysis; Article; carbon footprint; cluster analysis; controlled study; environmental parameters; explanatory variable; IPAT Kaya Identity Index; mathematical model; regression analysis; satellite imagery; greenhouse gas; gross national product | English | 2020 | 2020-08 | 10.3390/ijerph17165976 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Examining Liver Cancer Patients and a High-Risk Group in a Vulnerable Area: An Experience from the Ulleung Liver Cancer Prevention and Management Project | Ulleung county is a small island on the eastern side of the Korean peninsula. The Ulleung Liver Cancer Prevention and Management Project was launched in order to minimize newly developing liver cancer within this region. Population-based regional cancer registry data were analyzed to investigate the status and characteristics of registered liver cancer patients. The Interagency Workgroup of the project provided a special screening program from 1 November to 3 November 2018, and from 23 April to 25 April 2019, undertaking liver cancer screening and health behavior surveys. Logistic regression analysis was used to determine factors associated with recent liver cancer screening. In Ulleung county, hepatocellular carcinoma was identified as the main type of liver cancer, accompanied by a high incidence of hepatitis B. Approximately 25.0% of the participants were not aware of their liver condition. People who were aware of their liver condition and those who reported a general understanding of hepatitis B were more likely to have undergone recent liver cancer screening. To prevent the development and spread of the disease in the community, adequate infrastructure for cancer screening and an enhanced monitoring system are required, along with measures to create awareness to periodically determine liver condition in high-risk groups. | Ryu, Dong-Hee; Lee, Yu-Mi; Park, Ji Mi; Tak, Won Young; Hong, Nam-Soo | Catholic Univ Daegu, Sch Med, Dept Prevent Med, Daegu 42472, South Korea; Kyungpook Natl Univ, Sch Med, Dept Prevent Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Reg Canc Ctr, Med Ctr, Dept Prevent Med, Daegu 41404, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu 41944, South Korea | 57204067251; 57075191600; 57219567772; 7004074582; 54684167600 | ryudh@cu.ac.kr;yumilee@knu.ac.kr;feliz31@naver.com;wytak@knu.ac.kr;kusmac25@knu.ac.kr; | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | INT J ENV RES PUB HE | 1660-4601 | 17 | 21 | SCIE;SSCI | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.39 | 23.6 | 0 | 2025-06-25 | 0 | 0 | awareness; early detection of cancer; health behavior; liver neoplasm; residence characteristics | HEPATOCELLULAR-CARCINOMA; HEPATITIS-B | Awareness; Early detection of cancer; Health behavior; Liver neoplasm; Residence characteristics | Aged; Carcinoma, Hepatocellular; Female; Hepatitis B; Humans; Islands; Liver Neoplasms; Male; Mass Screening; Middle Aged; Republic of Korea; North Kyongsang; South Korea; Ulleung Island; cancer; disease treatment; management; monitoring system; public health; risk assessment; tumor; vulnerability; adult; aged; Article; cancer registry; cancer screening; female; hepatitis B; high risk population; human; incidence; liver cancer; liver cell carcinoma; major clinical study; male; middle aged; risk factor; South Korea; survival rate; hepatitis B; island (geological); liver cell carcinoma; liver tumor; mass screening | English | 2020 | 2020-11 | 10.3390/ijerph17217757 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Hyperhomocysteinemia Concurrent with Metabolic Syndrome Is Independently Associated with Chronic Kidney Disease among Community-Dwelling Adults in an Urban Korean Population | Elevated homocysteine (Hcy) levels and metabolic syndrome (MetS) are associated with chronic kidney disease (CKD). We investigated the combined effects of hyperhomocysteinemia (HHcy) and MetS on CKD among community-dwelling adults in an urban area of South Korea. We also identified the combination of HHcy and individual MetS components associated with the maximal risk of CKD. A retrospective cross-sectional study involving 19,311 health examinees between 2 January 2011 and 31 December 2015 was conducted. The participants were divided into four groups-namely, the HHcy-/MetS-, HHcy-/MetS+, HHcy+/MetS-, and HHcy+/MetS+ groups. CKD was defined as a low eGFR <60 mL/min/1.73 m(2) or albuminuria. The HHcy+/MetS+ group had a higher risk of CKD than the HHcy-/MetS+ group (odds ratio (OR): 1.750, p = 0.002 for males; OR: 3.224, p < 0.001 for females). The HHcy+/MetS+ group had a higher CKD risk than the HHcy+/MetS- group; however, the difference was not statistically significant (OR: 1.070, p = 0.712 for males; OR: 1.847, and p < 0.074 for females). HHcy concurrent with MetS increased the CKD risk. Among the combinations of HHcy and MetS components, the coexistence of HHcy and central obesity had the greatest effect on CKD. Therefore, the timely detection and treatment of HHcy and MetS are important for preventing CKD. | Moon, Hana; Ko, Hae-Jin; Kim, A-Sol | Daegu Catholic Univ, Sch Med, Dept Family Med, Daegu 42472, South Korea; Kyungpook Natl Univ, Sch Med, Dept Family Med, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Family Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Family Med, Chilgok Hosp, Daegu 41404, South Korea | 57188814366; 54393415700; 57203290656 | tnas1103@naver.com;liveforme@knu.ac.kr;deepai@knu.ac.kr; | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | INT J ENV RES PUB HE | 1660-4601 | 17 | 18 | SCIE;SSCI | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.39 | 23.6 | 0.47 | 2025-06-25 | 7 | 9 | metabolic syndrome; homocysteine; chronic kidney disease; proteinuria; cross-sectional study | RENAL-FUNCTION IMPAIRMENT; RISK-FACTORS; FAT DISTRIBUTION; HOMOCYSTEINE; DETERMINANTS; CHOLESTEROL; ALBUMIN; OBESITY; LEPTIN; CKD | Chronic kidney disease; Cross-sectional study; Homocysteine; Metabolic syndrome; Proteinuria | Adult; Cross-Sectional Studies; Female; Humans; Hyperhomocysteinemia; Independent Living; Male; Metabolic Syndrome; Middle Aged; Renal Insufficiency, Chronic; Republic of Korea; Retrospective Studies; Risk Factors; Urban Population; South Korea; albumin; C reactive protein; hemoglobin A1c; high density lipoprotein cholesterol; homocysteine; triacylglycerol; adult; health risk; metabolism; obesity; public health; urban area; adult; age; albumin blood level; albuminuria; amino acid blood level; Article; blood pressure; cholesterol blood level; chronic kidney failure; clinical evaluation; clinical feature; community dwelling person; comparative study; controlled study; cross-sectional study; disease association; female; glucose blood level; human; hyperhomocysteinemia; Korean (people); major clinical study; male; metabolic syndrome X; obesity; people by drinking status; physical activity; prevalence; protein blood level; retrospective study; risk factor; smoking; South Korea; triacylglycerol blood level; urban area; complication; independent living; middle aged; urban population | English | 2020 | 2020-09 | 10.3390/ijerph17186810 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Impacts of Thresholds of Gray Value for Cone-Beam Computed Tomography 3D Reconstruction on the Accuracy of Image Matching with Optical Scan | In cone-beam computed tomography (CBCT), the minimum threshold of the gray value of segmentation is set to convert the CBCT images to the 3D mesh reconstruction model. This study aimed to assess the accuracy of image registration of optical scans to 3D CBCT reconstructions created by different thresholds of grey values of segmentation in partial edentulous jaw conditions. CBCT of a dentate jaw was reconstructed to 3D mesh models using three different thresholds of gray value (-500, 500, and 1500), and three partially edentulous models with different numbers of remaining teeth (4, 8, and 12) were made from each 3D reconstruction model. To merge CBCT and optical scan data, optical scan images were registered to respective 3D reconstruction CBCT images using a point-based best-fit algorithm. The accuracy of image registration was assessed by measuring the positional deviation between the matched 3D images. The Kruskal-Wallis test and a post hoc Mann-Whitney U test with Bonferroni correction were used to compare the results between groups (alpha = 0.05). The correlations between the experimental factors were calculated using the two-way analysis of variance test. The positional deviations were lowest with the threshold of 500, followed by the threshold of 1500, and then -500. A significant interaction was found between the threshold of gray values and the number of remaining teeth on the registration accuracy. The most significant deviation was observed in the arch model with four teeth reconstructed with a gray-value threshold of -500. The threshold for the gray value of CBCT segmentation affects the accuracy of image registration of optical scans to the 3D reconstruction model of CBCT. The appropriate gray value that can visualize the anatomical structure should be set, especially when few teeth remain in the dental arch. | Park, Se-Won; Yoon, Ra Gyoung; Lee, Hyunwoo; Lee, Heon-Jin; Choi, Yong-Do; Lee, Du-Hyeong | Kyungpook Natl Univ, Sch Dent, Inst Translat Res Dent, Dept Prosthodont, Daegu 41940, South Korea; Eulji Univ, Nowon Eulji Med Ctr, Dept Radiol, Seoul 01830, South Korea; Natl Med Ctr, Dept Dent Clin, Seoul 04564, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Microbiol & Immunol, Daegu 41940, South Korea | 57217296951; 55340393500; 57218775082; 36462383000; 57217787575; 35770948000 | worm82@naver.com;yoonrg@gmail.com;surgeonsd@gmail.com;heonlee@knu.ac.kr;yongdochoi@naver.com;deweylee@knu.ac.kr; | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | INT J ENV RES PUB HE | 1660-4601 | 17 | 17 | SCIE;SSCI | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.39 | 23.6 | 0.47 | 2025-06-25 | 9 | 10 | cone-beam computed tomography; gray value; 3D reconstruction; accuracy; image registration | GUIDED IMPLANT-SURGERY; FABRICATION; PLACEMENT; ARTIFACTS; CBCT | 3D reconstruction; Accuracy; Cone-beam computed tomography; Gray value; Image registration | Algorithms; Cone-Beam Computed Tomography; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Tooth; accuracy assessment; algorithm; anatomy; correlation; image analysis; reconstruction; segmentation; three-dimensional modeling; threshold; tomography; visualization; Article; cone beam computed tomography; controlled study; diagnostic accuracy; diagnostic test accuracy study; diagnostic value; gray value; human; image analysis; image registration; imaging algorithm; jaw; Kruskal Wallis test; post hoc analysis; rank sum test; three-dimensional imaging; algorithm; diagnostic imaging; image processing; tooth | English | 2020 | 2020-09 | 10.3390/ijerph17176375 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Long-Term Effects of Air Pollutants on Mortality Risk in Patients with End-Stage Renal Disease | Long-term exposure to air pollutants significantly increases the morbidity and mortality associated with various diseases. However, little is known about the relationship between air pollutants and end-stage renal disease (ESRD)-related mortality. A total of 5041 patients who started dialysis between 2008 and 2015 were prospectively enrolled in the Clinical Research Center for End-Stage Renal Disease (CRC-ESRD) cohort study. We assigned a daily mean concentration of air pollutants (PM10, NO2, and SO2) to each participant. Time-varying Cox models were used to investigate the relationship between air pollutants and mortality in ESRD patients. During the follow-up period (mean 4.18 years), 1475 deaths occurred among 5041 participants. We found a significant long-term relationship between mortality risk and PM10 (HR 1.33, CI 1.13-1.58), NO2 (HR 1.46, CI 1.10-1.95), and SO2 (HR 1.07, CI 1.03-1.11). Elderly patients and patients who lived in metropolitan areas had an increased risk associated with PM10. Elderly patients also had increased risks associated NO2 and SO2. Long-term exposure to air pollutants had negative effects on mortality in ESRD patients. These effects were prominent in elderly patients who lived in metropolitan areas, suggesting that ambient air pollution, in addition to traditional risk factors, is important for the survival of these patients. | Jung, Jiyun; Park, Jae Yoon; Kim, Yong Chul; Lee, Hyewon; Kim, Ejin; Kim, Yong-Lim; Kim, Yon Su; Lee, Jung Pyo; Kim, Ho | Seoul Natl Univ, Sch Publ Hlth, Dept Biostat & Epidemiol, Seoul 08826, South Korea; Dongguk Univ, Ilsan Hosp, Dept Internal Med, Gyeonggi Do 10326, South Korea; Dongguk Univ, Coll Med, Dept Internal Med, Gyeongsangbuk Do 38066, South Korea; Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 03080, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Neuropsychiat, Gyeonggi Do 13620, South Korea; Seoul Natl Univ, Inst Hlth & Environm, Seoul 08826, South Korea; Kyungpook Natl Univ, Coll Med, Dept Internal Med, Daegu 41566, South Korea; Seoul Natl Univ, Boramae Med Ctr, Dept Internal Med, Seoul 07061, South Korea | ; Kim, Ho/AAS-2402-2021; Kim, Yong-Lim/AGK-3172-2022; Kim, Yong/L-8653-2019; Lee, Hyewon/KFQ-2230-2024 | 57211813518; 56603383500; 57026583000; 57190295653; 57199803032; 55633533600; 7410205767; 56028990400; 55313739600 | bestjudy@hanmail.net;nephrojyp@gmail.com;imyongkim@gmail.com;woniggo@gmail.com;plain@snu.ac.kr;ylkim@knu.ac.kr;yonsukim@snu.ac.kr;nephrolee@gmail.com;hokim@snu.ac.kr; | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | INT J ENV RES PUB HE | 1660-4601 | 17 | 2 | SCIE;SSCI | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.39 | 23.6 | 1.01 | 2025-06-25 | 19 | 22 | particulate matter; nitrogen dioxide; sulfur dioxide; ESRD; mortality | CHRONIC KIDNEY-DISEASE; PARTICULATE MATTER EXPOSURE; POLLUTION EXPOSURE; NITROGEN-DIOXIDE; PARTICLES; ASSOCIATIONS; COHORT; PM10 | ESRD; Mortality; Nitrogen dioxide; Particulate matter; Sulfur dioxide | Adult; Aged; Air Pollutants; Environmental Exposure; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrogen Dioxide; Particulate Matter; Proportional Hazards Models; Prospective Studies; Republic of Korea; Risk Factors; Sulfur Dioxide; Time Factors; nitric oxide; sulfur dioxide; nitrogen dioxide; sulfur dioxide; atmospheric pollution; disease prevalence; elderly population; metropolitan area; mortality risk; nitrogen dioxide; particulate matter; pollution effect; sulfur dioxide; adult; age distribution; air pollution; Article; body mass; Charlson Comorbidity Index; cohort analysis; concentration (parameter); dialysis; educational status; employment status; end stage renal disease; environmental exposure; female; follow up; geography; geriatric patient; health impact assessment; hemoglobin determination; human; major clinical study; male; marriage; morbidity; mortality; mortality risk; multicenter study; particulate matter; prospective study; risk assessment; risk factor; sex difference; social support; South Korea; survival rate; urban area; adverse event; aged; air pollutant; chronic kidney failure; environmental exposure; epidemiology; middle aged; mortality; proportional hazards model; time factor | English | 2020 | 2020-01-02 | 10.3390/ijerph17020546 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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