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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Mitigating phytotoxicity of tetracycline by metal-free 8-hydroxyquinoline functionalized carbon nitride photocatalyst Photooxidative removal of pharmaceuticals and organic dyes is an effective way to elimi-nate growing micropollutants. However, photooxidation often results in byproducts as sec-ondary hazardous substances such as phytotoxins. Herein, we found that photooxidation of common antibiotic tetracycline hydrochloride (TCH) over a metal-free 8-hydroxyquinoline (8-HQ) functionalized carbon nitride (CN) photocatalyst significantly reduces the TCH phy-totoxic effect. The phytotoxicity test of photocatalytic treated TCH-solution evaluated to-wards seed growth of Cicer arietinum plant model endowed natural root and shoot growth. This study highlights the conceptual insights in designing of metal-free photocatalyst for environmental remediation. (c) 2022 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V. Bhoyar, Toshali; Vidyasagar, Devthade; Umare, Suresh S. Visvesvaraya Natl Inst Technol VNIT, Dept Chem, Mat & Catalysis Lab, Nagpur 440010, Maharashtra, India; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea ; Bhoyar, Toshali/AAW-5211-2020; UMARE, SURESH/O-3982-2015; Vidyasagar, Devthade/O-3930-2015 57211356285; 57201674442; 6506241250 vidyasagar.devtade@gmail.com;ssumare1965@gmail.com; JOURNAL OF ENVIRONMENTAL SCIENCES J ENVIRON SCI 1001-0742 1878-7320 125 SCIE ENVIRONMENTAL SCIENCES 2023 5.9 17.2 1.03 2025-06-25 12 13 Carbon nitride; 8-Hydroxyquinoline; Tetracycline hydrochloride; Photocatalyst; Phytotoxicity; Cicer arietinum HYDROCHLORIDE DEGRADATION; CHARGE-TRANSFER; DOPED G-C3N4; REMOVAL; WATER; ANTIBIOTICS; SEMICONDUCTOR; FABRICATION; COMPOSITE 8-Hydroxyquinoline; Carbon nitride; Cicer arietinum; Photocatalyst; Phytotoxicity; Tetracycline hydrochloride Anti-Bacterial Agents; Metals; Nitriles; Oxyquinoline; Tetracycline; Photooxidation; Seed; Stripping (dyes); 8 quinolinol; antiinfective agent; cyanogen; metal; nitrile; tetracycline; 8-Hydroxyquinoline; Cicer arietinum; Functionalized; Hazardous substances; Metal free; Micropollutants; Organic dye; Phytotoxicity; Phytotoxins; Tetracycline hydrochloride; catalyst; concentration (composition); dye; photolysis; phytotoxicity; PPCP; Carbon nitride English 2023 2023-03 10.1016/j.jes.2021.10.032 바로가기 바로가기 바로가기 바로가기
Article The clinical course of hospitalized COVID-19 patients and aggravation risk prediction models: a retrospective, multi-center Korean cohort study Background: Understanding the clinical course and pivotal time points of COVID-19 aggravation is critical for enhancing patient monitoring. This retrospective, multi-center cohort study aims to identify these significant time points and associate them with potential risk factors, leveraging data from a sizable cohort with mild-to-moderate symptoms upon admission. Methods: This study included data from 1,696 COVID-19 patients with mild-to-moderate clinical severity upon admission across multiple hospitals in Daegu-Kyungpook Province (Daegu dataset) between February 18 and early March 2020 and 321 COVID-19 patients at Seoul Boramae Hospital (Boramae dataset) collected from February to July 2020. The approach involved: (1) identifying the optimal time point for aggravation using survival analyses with maximally selected rank statistics; (2) investigating the relationship between comorbidities and time to aggravation; and (3) developing prediction models through machine learning techniques. The models were validated internally among patients from the Daegu dataset and externally among patients from the Boramae dataset. Results: The Daegu dataset showed a mean age of 51.0 ± 19.6 years, with 8 days for aggravation and day 5 being identified as the pivotal point for survival. Contrary to previous findings, specific comorbidities had no notable impact on aggravation patterns. Prediction models utilizing factors including age and chest X-ray infiltration demonstrated promising performance, with the top model achieving an AUC of 0.827 in external validation for 5 days aggravation prediction. Conclusion: Our study highlights the crucial significance of the initial 5 days period post-admission in managing COVID-19 patients. The identification of this pivotal time frame, combined with our robust predictive models, provides valuable insights for early intervention strategies. This research underscores the potential of proactive monitoring and timely interventions in enhancing patient outcomes, particularly for those at risk of rapid aggravation. Our findings offer a meaningful contribution to understanding the COVID-19 clinical course and supporting healthcare providers in optimizing patient care and resource allocation. Copyright © 2024 Moon, Ham, Song, Lee, Goo, Oh, Lee, Kim and Park. Moon, Min Kyong; Ham, Hyeonjung; Song, Soo Min; Lee, Chanhee; Goo, Taewan; Oh, Bumjo; Lee, Seungyeoun; Kim, Shin-Woo; Park, Taesung Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, South Korea; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea; Department of Family Medicine, Seoul National University College of Medicine, Seoul, South Korea, Department of Family Medicine, SMG-SNU Boramae Medical Center, Seoul, South Korea; Department of Mathematics & Statistics, Sejong University, Seoul, South Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Statistics, Seoul National University, Seoul, South Korea 36123604500; 57221937854; 58411132800; 57219941916; 57207454491; 55272690200; 15754275000; 8710731500; 34668299500 ksw2kms@knu.ac.kr;tspark@stats.snu.ac.kr; Frontiers in Medicine FRONT MED-LAUSANNE N/A 2296-858X 10 SCIE MEDICINE, GENERAL & INTERNAL 2023 3.1 17.2 0.26 2025-06-25 1 case fatality rate; clinical decision support; COVID-19; disease progression; statistical model adult; age; aged; area under the curve; Article; body temperature; chronic kidney failure; chronic liver disease; cohort analysis; comorbidity; coronavirus disease 2019; dementia; diabetes mellitus; disease course; disease exacerbation; disease severity; female; health care personnel; heart failure; hospital admission; hospital patient; hospitalization; human; hypertension; internal validity; Korea; least absolute shrinkage and selection operator; machine learning; major clinical study; male; malignant neoplasm; mortality rate; multicenter study; myalgia; patient care; patient monitoring; people by smoking status; predictive model; regression analysis; resource allocation; retrospective study; risk factor; survival; thorax radiography English Final 2023 10.3389/fmed.2023.1239789 바로가기 바로가기 바로가기
Article Whole-body imaging of Camponotus atrox using photoacoustic microscopy for three-dimensional morphological analysis: A preliminary study Whole-body image analysis has been extensively applied in the field of entomology to identify differences in insect morphology. Although various conventional imaging techniques have been used for analyzing insect morphology, these often inflict damage on the sample during preparation and limitedly provide superficial in-formation. To overcome the conventional limitations, in this study, we noninvasively observed the morpho-logical structures of the ant Camponotus atrox, from the whole body to specific parts, over a wide scan range using optical-resolution photoacoustic microscopy (PAM). Based on the obtained photoacoustic maximum amplitude projection images, various structures of the ant, including the antenna, compound eyes, coxa, mandibles, mes-onotum, propodeum, petiole, sting, and tergite, could be discerned by covering the entire ant body. In addition, we attained the morphological structures in detail by magnifying three specific parts, namely, the compound eyes, head, and thorax. Furthermore, we non-destructively analyzed the internal structure of various organs, such as the compound eyes, social stomach, and hindgut, via depth profiling of cross-sectional images. Finally, by implementing an algorithm, we visualized the depth-resolved en-face images of internal structures according to a constant depth interval. The findings established that the PAM system could identify not only each external morphological feature of the ant visible but also the sublayers of its internal structures. This study demonstrates the feasibility of PAM for contributing to performing morphological studies in entomological research. Kim, Hyunmo; Seong, Daewoon; Han, Sangyeob; Cho, Hoseong; Lee, Jaeyul; Wijesinghe, Ruchire Eranga; Jeon, Mansik; Kim, Jeehyun Kyungpook Natl Univ, Coll IT Engn, Sch Elect & Elect Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, ICT Convergence Res Ctr, 80 Daehak Ro, Daegu 41566, South Korea; Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA; Univ Sri Jayewardenepura, Fac Technol, Dept Mat & Mech Technol, Pitipana 10200, Homagama, Sri Lanka Wijesinghe, Ruchire/K-3797-2016; Lee, Junsoo/IUO-9627-2023; Han, Sangyeob/W-3206-2018 58078407800; 57212512353; 57193695305; 57209416599; 57188689420; 57214877268; 24171094000; 7601373350 msjeon@knu.ac.kr;jeehk@knu.ac.kr; OPTICS AND LASER TECHNOLOGY OPT LASER TECHNOL 0030-3992 1879-2545 167 SCIE OPTICS;PHYSICS, APPLIED 2023 4.6 17.2 0.27 2025-06-25 2 2 Ant; Camponotus atrox; Whole-body imaging; Morphology; Optical imaging; Photoacoustic microscopy HYMENOPTERA-FORMICIDAE; HIGH-RESOLUTION; ANT; TOMOGRAPHY; LIMITATIONS; ECOLOGY; CT Ant; Camponotus atrox; Morphology; Optical imaging; Photoacoustic microscopy; Whole-body imaging Antennas; Depth profiling; Image analysis; Photoacoustic microscopy; Ant; Body image; Camponotu atrox; Compound eye; Internal structure; Morphological analysis; Morphological structures; Optical imaging; Whole-body; Whole-body imaging; Morphology English 2023 2023-12 10.1016/j.optlastec.2023.109754 바로가기 바로가기 바로가기 바로가기
Article A Search for Pulsars around Sgr A* in the First Event Horizon Telescope Data Set In 2017 the Event Horizon Telescope (EHT) observed the supermassive black hole at the center of the Milky Way, Sagittarius A* (Sgr A*), at a frequency of 228.1 GHz (lambda = 1.3 mm). The fundamental physics tests that even a single pulsar orbiting Sgr A* would enable motivate searching for pulsars in EHT data sets. The high observing frequency means that pulsars-which typically exhibit steep emission spectra-are expected to be very faint. However, it also negates pulse scattering, an effect that could hinder pulsar detections in the Galactic center. Additionally, magnetars or a secondary inverse Compton emission could be stronger at millimeter wavelengths than at lower frequencies. We present a search for pulsars close to Sgr A* using the data from the three most sensitive stations in the EHT 2017 campaign: the Atacama Large Millimeter/submillimeter Array, the Large Millimeter Telescope, and the IRAM 30 m Telescope. We apply three detection methods based on Fourier-domain analysis, the fast folding algorithm, and single-pulse searches targeting both pulsars and burst-like transient emission. We use the simultaneity of the observations to confirm potential candidates. No new pulsars or significant bursts were found. Being the first pulsar search ever carried out at such high radio frequencies, we detail our analysis methods and give a detailed estimation of the sensitivity of the search. We conclude that the EHT 2017 observations are only sensitive to a small fraction (less than or similar to 2.2%) of the pulsars that may exist close to Sgr A*, motivating further searches for fainter pulsars in the region. Torne, Pablo; Liu, Kuo; Eatough, Ralph P.; Wongphechauxsorn, Jompoj; Cordes, James M.; Desvignes, Gregory; De Laurentis, Mariafelicia; Kramer, Michael; Ransom, Scott M.; Chatterjee, Shami; Wharton, Robert; Karuppusamy, Ramesh; Blackburn, Lindy; Janssen, Michael; Chan, Chi-Kwan; Crew, Geoffrey B.; Matthews, Lynn D.; Goddi, Ciriaco; Rottmann, Helge; Wagner, Jan; Sanchez, Salvador; Ruiz, Ignacio; Abbate, Federico; Bower, Geoffrey C.; Salamanca, Juan J.; Gomez-Ruiz, Arturo I.; Herrera-Aguilar, Alfredo; Jiang, Wu; Lu, Ru-Sen; Pen, Ue-Li; Raymond, Alexander W.; Shao, Lijing; Shen, Zhiqiang; Paubert, Gabriel; Sanchez-Portal, Miguel; Kramer, Carsten; Castillo, Manuel; Navarro, Santiago; John, David; Schuster, Karl-Friedrich; Johnson, Michael D.; Rygl, Kazi L. J.; Akiyama, Kazunori; Alberdi, Antxon; Alef, Walter; Algaba, Juan Carlos; Anantua, Richard; Asada, Keiichi; Azulay, Rebecca; Bach, Uwe; Baczko, Anne-Kathrin; Ball, David; Balokovic, Mislav; Barrett, John; Baubock, Michi; Benson, Bradford A.; Bintley, Dan; Blundell, Raymond; Bouman, Katherine L.; Boyce, Hope; Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broderick, Avery E.; Broguiere, Dominique; Bronzwaer, Thomas; Bustamante, Sandra; Byun, Do-Young; Carlstrom, John E.; Ceccobello, Chiara; Chael, Andrew; Chang, Dominic O.; Chatterjee, Koushik; Chen, Ming-Tang; Chen, Yongjun; Cheng, Xiaopeng; Cho, Ilje; Christian, Pierre; Conroy, Nicholas S.; Conway, John E.; Crawford, Thomas M.; Cruz-Osorio, Alejandro; Cui, Yuzhu; Dahale, Rohan; Davelaar, Jordy; Deane, Roger; Dempsey, Jessica; Dexter, Jason; Dhruv, Vedant; Doeleman, Sheperd S.; Dougal, Sean; Dzib, Sergio A.; Emami, Razieh; Falcke, Heino; Farah, Joseph; Fish, Vincent L.; Fomalont, Ed; Ford, H. Alyson; Foschi, Marianna; Fraga-Encinas, Raquel; Freeman, William T.; Friberg, Per; Fromm, Cistian M.; Fuentes, Antonio; Galison, Peter; Gammie, Charles F.; Garcia, Roberto; Gentaz, Olivier; Georgiev, Boris; Gold, Roman; Gomez, Jose L.; Gu, Minfeng; Gurwell, Mark; Hada, Kazuhiro; Haggard, Daryl; Haworth, Kari; Hecht, Michael H.; Hesper, Ronald; Heumann, Dirk; Ho, Luis C.; Ho, Paul; Honma, Mareki; Huang, Chih-Wei L.; Huang, Lei; Hughes, David H.; Ikeda, Shiro; Impellizzeri, C. M. Violette; Inoue, Makoto; Issaoun, Sara; James, David J.; Jannuzi, Buell T.; Jeter, Britton; Jimenez-Rosales, Alejandra; Jorstad, Svetlana; Joshi, Abhishek V.; Jung, Taehyun; Karami, Mansour; Kawashima, Tomohisa; Keating, Garrett K.; Kettenis, Mark; Kim, Dong-Jin; Kim, Jae-Young; Kim, Jongsoo; Kim, Junhan; Kino, Motoki; Koay, Jun Yi; Kocherlakota, Prashant; Kofuji, Yutaro; Koyama, Shoko; Krichbaum, Thomas P.; Kuo, Cheng-Yu; La Bella, Noemi; Lauer, Tod R.; Lee, Daeyoung; Lee, Sang-Sung; Leung, Po Kin; Levis, Aviad; Li, Zhiyuan; Lico, Rocco; Lindahl, Greg; Lindqvist, Michael; Lisakov, Mikhail; Liu, Jun; Liuzzo, Elisabetta; Lo, Wen-Ping; Lobanov, Andrei P.; Loinard, Laurent; Lonsdale, Colin J.; MacDonald, Nicholas R.; Mao, Jirong; Marchili, Nicola; Markoff, Sera; Marrone, Daniel P.; Marscher, Alan P.; Marti-Vidal, Ivan; Matsushita, Satoki; Medeiros, Lia; Menten, Karl M.; Michalik, Daniel; Mizuno, Izumi; Mizuno, Yosuke; Moran, James M.; Moriyama, Kotaro; Moscibrodzka, Monika; Mueller, Cornelia; Mueller, Hendrik; Mus, Alejandro; Musoke, Gibwa; Myserlis, Ioannis; Nadolski, Andrew; Nagai, Hiroshi; Nagar, Neil M.; Nakamura, Masanori; Narayan, Ramesh; Narayanan, Gopal; Natarajan, Iniyan; Nathanail, Antonios; Neilsen, Joey; Neri, Roberto; Ni, Chunchong; Noutsos, Aristeidis; Nowak, Michael A.; Oh, Junghwan; Okino, Hiroki; Olivares, Hector; Ortiz-Leon, Gisela N.; Oyama, Tomoaki; Ozel, Feryal; Palumbo, Daniel C. M.; Paraschos, Georgios Filippos; Park, Jongho; Parsons, Harriet; Patel, Nimesh; Pesce, Dominic W.; Pietu, Vincent; Plambeck, Richard; PopStefanija, Aleksandar; Porth, Oliver; Potzl, Felix M.; Prather, Ben; Preciado-Lopez, Jorge A.; Psaltis, Dimitrios; Pu, Hung-Yi; Ramakrishnan, Venkatessh; Rao, Ramprasad; Rawlings, Mark G.; Rezzolla, Luciano; Ricarte, Angelo; Ripperda, Bart; Roelofs, Freek; Rogers, Alan; Ros, Eduardo; Romero-Canizales, Cristina; Roshanineshat, Arash; Roy, Alan L.; Ruszczyk, Chet; Sanchez-Arguelles, David; Sasada, Mahito; Satapathy, Kaushik; Savolainen, Tuomas; Schloerb, F. Peter; Schonfeld, Jonathan; Small, Des; Sohn, Bong Won; SooHoo, Jason; Souccar, Kamal; Sun, He; Tetarenko, Alexandra J.; Tiede, Paul; Tilanus, Remo P. J.; Titus, Michael; Toscano, Teresa; Traianou, Efthalia; Trent, Tyler; Trippe, Sascha; Turk, Matthew; van Bemmel, Ilse; van Langevelde, Huib Jan; van Rossum, Daniel R.; Vos, Jesse; Ward-Thompson, Derek; Wardle, John; Weintroub, Jonathan; Wex, Norbert; Wielgus, Maciek; Wiik, Kaj; Witzel, Gunther; Wondrak, Michael F.; Wong, George N.; Wu, Qingwen; Yadlapalli, Nitika; Yamaguchi, Paul; Yfantis, Aristomenis; Yoon, Doosoo; Young, Andre; Young, Ken; Younsi, Ziri; Yu, Wei; Yuan, Feng; Yuan, Ye-Fei; Zensus, J. Anton; Zhang, Shuo; Zhao, Guang-Yao; Zhao, Shan-Shan Inst Radioastron Millimetr, Ave Div Pastora 7,Local 20, E-18012 Granada, Spain; Max Planck Inst Radioastron, Auf Hugel 69, D-53121 Bonn, Germany; Chinese Acad Sci, Natl Astron Observ, 20A Datun Rd, Beijing 100101, Peoples R China; Cornell Univ, Cornell Ctr Astrophys & Planetary Sci, Ithaca, NY 14853 USA; Univ Paris, Sorbonne Univ, Univ PSL, LESIA,Observ Paris,CNRS, 5 Pl Jules Janssen, F-92195 Meudon, France; Univ Napoli Federico II, Dipartimento Fis E Pancini, Compl Univ Monte S Angelo, Edificio G,Via Cinthia, I-80126 Naples, Italy; Goethe Univ Frankfurt, Inst Theoret Phys, Max Laue Str 1, D-60438 Frankfurt, Germany; Compl Univ Monte S Angelo, INFN Sez Napoli, Edificio G,Via Cinthia, I-80126 Naples, Italy; Univ Manchester, Sch Phys & Astron, Jodrell Bank Ctr Astrophys, Manchester M13 9PL, Lancs, England; Natl Radio Astron Observ, 520 Edgemont Rd, Charlottesville, VA 22903 USA; CALTECH, Jet Prop Lab, Pasadena, CA 91109 USA; Harvard Univ, Black Hole Initiat, 20 Garden St, Cambridge, MA 02138 USA; Harvard & Smithsonian, Ctr Astrophys, 60 Garden St, Cambridge, MA 02138 USA; Univ Arizona, Steward Observ, 933 N Cherry Ave, Tucson, AZ 85721 USA; Univ Arizona, Dept Astron, 933 N Cherry Ave, Tucson, AZ 85721 USA; Univ Arizona, Data Sci Inst, 1230 N Cherry Ave, Tucson, AZ 85721 USA; Univ Arizona, Program Appl Math, 617 N Santa Rita, Tucson, AZ 85721 USA; MIT, Haystack Observ, 99 Millstone Rd, Westford, MA 01886 USA; Univ Sao Paulo, Inst Astron Geofis & Ciencias Atmosfer, R do Matao 1226, BR-05508090 Sao Paulo, SP, Brazil; Univ Cagliari, Dipartimento Fis, SP Monserrato Sestu Km 0 7, Monserrato, CA, Italy; INAF Osservatorio Astron Cagliari, Via Sci 5, I-09047 Selargius, CA, Italy; INFN, Sez Cagliari, I-09042 Monserrato, CA, Italy; Acad Sinica, Inst Astron & Astrophys, 645 N Aohoku Pl, Hilo, HI 96720 USA; Univ Hawaii Manoa, Dept Phys & Astron, 2505 Correa Rd, Honolulu, HI 96822 USA; Univ Oviedo, Escuela Politecn Ingn, Dept Estadist & IO, E-33071 Gijon, Spain; Inst Nacl Astrofis Optic & Elect, Apartado Postal 51 & 216, Puebla 72000, Puebla, Mexico; Consejo Nacl Ciencia & Technol, Av Insurgentes 1582, Mexico City 03940, Mexico; Benemerita Univ Autonoma Puebla, Inst Fis, Edificio IF 1,Ciudad Univ, Puebla 72570, Mexico; Chinese Acad Sci, Shanghai Astron Observ, 80 Nandan Rd, Shanghai 200030, Peoples R China; Chinese Acad Sci, Key Lab Radio Astron, Nanjing 210008, Peoples R China; Acad Sinica, Inst Astron & Astrophys, 11F Astron Math Bldg,AS NTU 1,Sec 4,Roosevelt Rd, Taipei 10617, Taiwan; Perimeter Inst Theoret Phys, 31 Caroline St North, Waterloo, ON N2L 2Y5, Canada; Univ Toronto, Canadian Inst Theoret Astrophys, 60 St George St, Toronto, ON M5S 3H8, Canada; Univ Toronto, Dunlap Inst Astron & Astrophys, 50 St George St, Toronto, ON M5S 3H4, Canada; Canadian Inst Adv Res, 180 Dundas St West, Toronto, ON M5G IZ8, Canada; Peking Univ, Kavli Inst Astron & Astrophys, Beijing 100871, Peoples R China; Inst Radioastron Millimetr, 300 Rue Piscine, F-38406 St Martin Dheres, France; INAF Ist Radioastron, Italian ALMA Reg Ctr, Via P Gobetti 101, I-40129 Bologna, Italy; Italian ALMA Reg Ctr, Via P Gobetti 101, I-40129 Bologna, Italy; Natl Astron Observ Japan, 2-21-1 Osawa, Mitaka, Tokyo 1818588, Japan; CSIC, Inst Astrofis Andalucia, Glorieta Astronomia S-N, E-18008 Granada, Spain; Univ Malaya, Fac Sci, Dept Phys, Kuala Lumpur 50603, Malaysia; Univ Texas San Antonio, Dept Phys & Astron, One UTSA Circle, San Antonio, TX 78249 USA; Univ Valencia, Dept Astron & Astrofis, C Dr Moliner 50, E-46100 Burjassot, Valencia, Spain; Univ Valencia, Observ Astron, C Catedratico Jose Beltran 2, E-46980 Paterna, Valencia, Spain; Chalmers Univ Technol, Onsala Space Observ, Dept Space Earth & Environm, SE-43992 Onsala, Sweden; Yale Univ, Yale Ctr Astron & Astrophys, 52 Hillhouse Ave, New Haven, CT 06511 USA; Univ Illinois, Dept Phys, 1110 W Green St, Urbana, IL 61801 USA; Fermilab Natl Accelerator Lab, MS209,POB 500, Batavia, IL 60510 USA; Univ Chicago, Dept Astron & Astrophys, 5640 S Ellis Ave, Chicago, IL 60637 USA; East Asian Observ, 660 N Aohoku Pl, Hilo, HI 96720 USA; James Clerk Maxwell Telescope JCMT, 660 N Aohoku Pl, Hilo, HI 96720 USA; CALTECH, 1200 E Calif Blvd, Pasadena, CA 91125 USA; McGill Univ, Dept Phys, 3600 Rue Univ, Montreal, PQ H3A 2T8, Canada; McGill, Trottier Space Inst, 3550 Rue Univ, Montreal, PQ H3A 2A7, Canada; Radboud Univ Nijmegen, Inst Math Astrophys & Particle Phys IMAPP, Dept Astrophys, POB 9010, NL-6500 GL Nijmegen, Netherlands; Univ Waterloo, Dept Phys & Astron, 200 Univ Ave West, Waterloo, ON N2L 3G1, Canada; Univ Waterloo, Waterloo Ctr Astrophys, Waterloo, ON N2L 3G1, Canada; Univ Massachusetts, Dept Astron, Amherst, MA 01003 USA; Korea Astron & Space Sci Inst, Daedeok Daero 776, Daejeon 34055, South Korea; Univ Sci & Technol, Gajeong Ro 217, Daejeon 34113, South Korea; Univ Chicago, Kavli Inst Cosmol Phys, 5640 S Ellis Ave, Chicago, IL 60637 USA; Univ Chicago, Dept Phys, 5720 S Ellis Ave, Chicago, IL 60637 USA; Univ Chicago, Enrico Fermi Inst, 5640 S Ellis Ave, Chicago, IL 60637 USA; Princeton Univ, Princeton Grav Initiat, Jadwin Hall, Princeton, NJ 08544 USA; Fairfield Univ, Dept Phys, 1073 N Benson Rd, Fairfield, CT 06824 USA; Univ Illinois, Dept Astron, 1002 W Green St, Urbana, IL 61801 USA; Zhejiang Lab, Res Ctr Intelligent Comp Platforms, Hangzhou 311100, Peoples R China; Shanghai Jiao Tong Univ, Tsung Dao Lee Inst, Shengrong Rd 520, Shanghai 201210, Peoples R China; Columbia Univ, Dept Astron, 550 W 120th St, New York, NY 10027 USA; Columbia Univ, Columbia Astrophys Lab, 550 W 120th St, New York, NY 10027 USA; Flatiron Inst, Ctr Comp Astrophys, 162 Fifth Ave, New York, NY 10010 USA; Univ Witwatersrand, Wits Ctr Astrophys, 1 Jan Smuts Ave, ZA-2050 Johannesburg, South Africa; Univ Pretoria, Dept Phys, ZA-0028 Pretoria, South Africa; Rhodes Univ, Dept Phys & Elect, Ctr Radio Astron Techn & Technol, ZA-6140 Makhanda, South Africa; ASTRON, Oude Hoogeveensedijk 4, NL-7991 PD Dwingeloo, Netherlands; Univ Colorado, JILA, Boulder, CO 80309 USA; Univ Colorado, Dept Astrophys & Planetary Sci, Boulder, CO 80309 USA; Las Cumbres Observ, 6740 Cortona Dr,Suite 102, Goleta, CA 93117 USA; Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA; MIT, Dept Elect Engn & Comp Sci, 32 D476,77 Massachusetts Ave, Cambridge, MA 02142 USA; Google Res, 355 Main St, Cambridge, MA 02142 USA; Univ Wurzburg, Inst Theoret Phys & Astrophys, Emil Fischer Str 31, D-97074 Wurzburg, Germany; Harvard Univ, Dept Hist Sci, Cambridge, MA 02138 USA; Harvard Univ, Dept Phys, Cambridge, MA 02138 USA; Univ Illinois, NCSA, 1205 W Clark St, Urbana, IL 61801 USA; Univ Southern Denmark, CP3 Origins, Campusvej 55, DK-5230 Odense M, Denmark; Chinese Acad Sci, Key Lab Res Galaxies & Cosmol, Shanghai 200030, Peoples R China; Natl Astron Observ Japan, Mizusawa VLBI Observ, 2-12 Hoshigaoka, Mizusawa, Iwate 0230861, Japan; Grad Univ Adv Studies SOKENDAI, Dept Astron Sci, 2-21-1 Osawa, Mitaka, Tokyo 1818588, Japan; Univ Groningen, Kapteyn Astron Inst, NOVA Submillimeter Instrumentat Grp, Landleven 12, NL-9747 AD Groningen, Netherlands; Peking Univ, Sch Phys, Dept Astron, Beijing 100871, Peoples R China; Univ Tokyo, Grad Sch Sci, Dept Astron, 7-3-1 Hongo,Bunkyo Ku, Tokyo 1130033, Japan; Inst Stat Math, 10-3 Midori Cho, Tachikawa, Tokyo 1908562, Japan; Grad Univ Adv Studies SOKENDAI, Dept Stat Sci, 10-3 Midori Cho, Tachikawa, Tokyo 1908562, Japan; Univ Tokyo, Kavli Inst Phys & Math Universe, 5-1-5 Kashiwanoha, Kashiwa, Chiba 2778583, Japan; Leiden Univ, Leiden Observ, POB 2300, NL-9513 RA Leiden, Netherlands; ASTRAVEO LLC, POB 1668, Gloucester, MA 01931 USA; Appl Mat Inc, 35 Dory Rd, Gloucester, MA 01930 USA; Boston Univ, Inst Astrophys Res, 725 Commonwealth Ave, Boston, MA 02215 USA; Univ Tokyo, Inst Cosmic Ray Res, 5-1-5 Kashiwanoha, Kashiwa, Chiba 2778582, Japan; Joint Inst VLBI ERIC JIVE, Oude Hoogeveensedijk 4, NL-7991 PD Dwingeloo, Netherlands; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 702701, South Korea; Kogakuin Univ Technol & Engn, Acad Support Ctr, 2665-1 Nakano, Hachioji, Tokyo 1920015, Japan; Niigata Univ, 8050 Ikarashi Nino Cho,Nishi Ku, Niigata 9502181, Japan; Natl Sun Yat Sen Univ, Dept Phys, 70 Lien Hai Rd, Kaohsiung 80424, Taiwan; Natl Opt Astron Observ, 950 N Cherry Ave, Tucson, AZ 85719 USA; Chinese Univ Hong Kong, Dept Phys, Shatin, Hong Kong, Peoples R China; Nanjing Univ, Sch Astron & Space Sci, Nanjing 210023, Peoples R China; Nanjing Univ, Key Lab Modern Astron & Astrophys, Nanjing 210023, Peoples R China; INAF, Ist Radioastron, Via P Gobetti 101, I-40129 Bologna, Italy; Natl Taiwan Univ, Dept Phys, 1,Sec 4,Roosevelt Rd, Taipei 10617, Taiwan; Univ Nacl Autonoma Mexico, Inst Radioastron & Astrofis, Morelia 58089, Michoacan, Mexico; Chinese Acad Sci, Yunnan Observ, Kunming 650011, Yunnan, Peoples R China; Chinese Acad Sci, Ctr Astron Mega Sci, 20A Datun Rd, Beijing 100012, Peoples R China; Chinese Acad Sci, Key Lab Struct & Evolut Celestial Objects, Kunming 650011, Yunnan, Peoples R China; Univ Amsterdam, Astron Inst Anton Pannekoek, Sci Pk 904, NL-1098 XH Amsterdam, Netherlands; Univ Amsterdam, Gravitat & Astroparticle Phys Amsterdam GRAPPA, Sci Pk 904, NL-1098 XH Amsterdam, Netherlands; Inst Adv Study, Sch Nat Sci, 1 Einstein Dr, Princeton, NJ 08540 USA; European Space Res & Technol Ctr ESA ESTEC, Directorate Sci, Sci Support Off, Keplerlaan 1, NL-2201 AZ Noordwijk, Netherlands; Shanghai Jiao Tong Univ, Sch Phys & Astron, 800 Dongchuan Rd, Shanghai 200240, Peoples R China; Univ Concepcion, Astron Dept, Casilla 160 C, Concepcion, Chile; Hachinohe Coll, Natl Inst Technol, 16-1 Uwanotai, Hachinohe, Aomori 0391192, Japan; Acad Athens, Res Ctr Astron, Soranou Efessiou 4, Athens 11527, Greece; Villanova Univ, Dept Phys, 800 Lancaster Ave, Villanova, PA 19085 USA; Washington Univ, Phys Dept, CB 1105, St Louis, MO 63130 USA; Sejong Univ, 209 Neungdong Ro, Seoul, South Korea; Georgia Inst Technol, Sch Phys, 837 State St NW, Atlanta, GA 30332 USA; Univ Calif Berkeley, Radio Astron Lab, Berkeley, CA 94720 USA; Fdn Res & Technol Hellas, Inst Astrophys, Iraklion 7110, Greece; Natl Taiwan Normal Univ, Dept Phys, 88,Sec 4,Tingzhou Rd, Taipei 116, Taiwan; Natl Taiwan Normal Univ, Ctr Astron & Gravitat, 88,Sec 4,Tingzhou Rd, Taipei 116, Taiwan; Univ Turku, Finnish Ctr Astron ESO, FI-20014 Turku, Finland; Aalto Univ, Metsahovi Radio Observ, Metsahovintie 114, FI-02540 Kylmala, Finland; Gemini Observ, NSF NOIRLab, 670 N Aohoku Pl, Hilo, HI 96720 USA; Frankfurt Inst Adv Studies, Ruth Moufang Str 1, D-60438 Frankfurt, Germany; Trinity Coll Dublin, Sch Math, Dublin 2, Ireland; Princeton Univ, Dept Astrophys Sci, Peyton Hall, Princeton, NJ 08544 USA; Tokyo Inst Technol, Dept Phys, 2-12-1 Ookayama,Meguro Ku, Tokyo 1528551, Japan; Hiroshima Univ, Hiroshima Astrophys Sci Ctr, 1-3-1 Kagamiyama, Higashihiroshima, Hiroshima 7398526, Japan; Aalto Univ, Dept Elect & Nanoengn, PL 15500, FI-00076 Aalto, Finland; Yonsei Univ, Dept Astron, Yonsei Ro 50, Seoul 03722, South Korea; Univ Lethbridge, Dept Phys & Astron, Lethbridge, AB T1K 3M4, Canada; Netherlands Org Sci Res NWO, POB 93138, NL-2509 AC The Hague, Netherlands; Seoul Natl Univ, Dept Phys & Astron, Seoul 08826, South Korea; Univ New Mexico, Dept Phys & Astron, Albuquerque, NM 87131 USA; Univ Cent Lancashire, Jeremiah Horrocks Inst, Preston PR1 2HE, Lancs, England; Brandeis Univ, Phys Dept, 415 South St, Waltham, MA 02453 USA; Univ Turku, Tuorla Observ, Dept Phys & Astron, Turku, Finland; Radboud Univ Nijmegen, Radboud Excellence Fellow, Nijmegen, Netherlands; Princeton Univ, Princeton Grav Initiat, Princeton, NJ 08544 USA; Huazhong Univ Sci & Technol, Sch Phys, Wuhan 430074, Hubei, Peoples R China; Univ Coll London, Mullard Space Sci Lab, Holmbury St Mary, Dorking RH5 6NT, Surrey, England; Univ Chinese Acad Sci, Sch Astron & Space Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China; Univ Sci & Technol China, Astron Dept, Hefei 230026, Peoples R China; Bard Coll, 30 Campus Rd, Annandale on Hudson, NY 12504 USA ; Lico, Rocco/L-8308-2019; Algaba, Juan Carlos/AAB-4526-2022; Cui, Yuzhu/MBG-4427-2025; Jorstad, Svetlana/AAM-3279-2021; Ikeda, Shiro/E-1736-2016; Li, Zhiyuan/GWM-6492-2022; De Laurentis, Mariafelicia/J-7157-2015; Liu, Kuo/LIF-0258-2024; Lobanov, Andrei/G-5891-2014; Chatterjee, Shami/AAE-8374-2022; Barrett, John/K-8867-2014; Loinard, Laurent/MCX-8116-2025; Bloch, Michael/O-7845-2017; Sasada, Mahito/ABD-5766-2020; Torne, Pablo/MIP-4319-2025; Kim, Junhan/LTZ-1683-2024; Zamorano, Jose/ABU-6635-2022; Wielgus, Maciek/JEF-6647-2023; Pen, Ue-Li/AAX-6083-2021; Park, Jongho/JFB-2747-2023; Rao, Ramprasad/L-2115-2017; Rezzolla, Luciano/JPK-1036-2023; Olivares Sanchez, Hector Raul/KWU-1646-2024; Turk, Matthew/GXV-9589-2022; 浅田圭一, Keiichi/ABC-2456-2020; Lee, Dae-Young/AAI-6981-2020; ho, paul/AAZ-5108-2020; Matsushita, Satoki/ABD-5562-2020; Goddi, Ciriaco/AAN-4033-2021; Kino, Motoki/LQK-9129-2024; Liu, Kuo/AAM-1431-2021; Kawashima, Tomohisa/GYD-8953-2022; Gold, Roman/AAX-5851-2021; Bach, Udo/F-3880-2012; Myserlis, Ioannis/MCY-5944-2025; Lisakov, Mikhail/JAX-3277-2023; nagar, neil/AAG-4543-2020; Lisakov, Mikhail/M-6034-2013; shuo, zhang/KGM-7804-2024; huang, lei/GQP-8739-2022; Schuster, Karling/JMP-9441-2023; Fuentes, Antonio/R-3900-2019; Wong, George/AAL-1016-2021; Kim, Jae-Young/IUO-6466-2023; Azulay, Rebecca/U-2560-2017; Mellon, Michael/C-3456-2016; Mueller, Hendrik/JXL-4021-2024; Wagner, Jan/LTZ-8501-2024; Koay, Jun/E-4952-2015; Cheng, Xiaopeng/ABX-5356-2022; Baczko, Anne-Kathrin/AAW-2724-2020; Bower, Geoffrey/ABC-8386-2020; 韓之強, Chih/AAZ-8498-2020; Castillo, Manuel/F-9257-2014; Sanchez, David/KIH-3142-2024; ABBATE, Federico/IYJ-8703-2023; Olivares, Hector/KWU-1646-2024; Ceccobello, Chiara/AAD-4283-2022; Ramakrishnan, Venkatessh/C-8628-2017; Cho, Ilje/LSL-5339-2024; Moriyama, Kotaro/NGQ-8643-2025; Lee, Sang-Sung/AFS-2722-2022; Cruz Osorio, Alejandro/GQQ-8823-2022; Pesce, Dominic/AAX-6358-2021; Toscano Domingo, Teresa/ITV-2430-2023; Ros, Eduardo/B-1014-2015; Kramer, Michael/KLY-3270-2024; Shao, Lijing/GRO-6046-2022; Impellizzeri, Violette/JQW-3813-2023; HUANG, LING/HTR-1819-2023 57190767230; 56227604600; 26029120300; 57669517900; 7102087612; 6603366433; 57217298918; 23968081200; 7005562794; 35500782800; 55262937300; 24544483600; 35271380400; 57213908458; 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7007019201; 57702184700; 57204824800; 57208316147; 8559107900; 24077308500; 6602323834; 6603776865; 36057630500; 57220895149; 7004002583; 36613480200; 23487579300; 6603048295; 52164611300; 7004299975; 24833754300; 57189852229; 57208320165; 57207446777; 57221861625; 56721395200; 57779474100; 54384535700; 56221262400; 7402601128; 55347813900; 55804393100; 57203725419; 35185850600; 7004929291; 55767566800; 55478882500; 55877039000 torne@iram.es;kliu@mpifr-bonn.mpg.de; ASTROPHYSICAL JOURNAL ASTROPHYS J 0004-637X 1538-4357 959 1 SCIE ASTRONOMY & ASTROPHYSICS 2023 4.8 17.3 0.59 2025-06-25 4 6 GALACTIC-CENTER MAGNETAR; SUPERMASSIVE BLACK-HOLE; STAR-FORMATION HISTORY; GENERAL-RELATIVITY; RADIO OBSERVATIONS; STELLAR DYNAMICS; GRAVITY TESTS; RESULTS. VI.; DISCOVERY; MILKY English 2023 2023-12-01 10.3847/1538-4357/acf4f2 바로가기 바로가기 바로가기 바로가기
Article ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes Recent developments in genome sequencing have expanded the knowledge of genetic factors associated with late-onset Alzheimer's disease (AD). Among them, genetic variant epsilon 4 of the APOE gene (APOE4) confers the greatest disease risk. Dysregulated glucose metabolism is an early pathological feature of AD. Using isogenic ApoE3 and ApoE4 astrocytes derived from human induced pluripotent stem cells, we find that ApoE4 increases glycolytic activity but impairs mitochondrial respiration in astrocytes. Ultrastructural and autophagy flux analyses show that ApoE4-induced cholesterol accumulation impairs lysosome-dependent removal of damaged mitochondria. Acute treatment with cholesterol-depleting agents restores autophagic activity, mitochondrial dynamics, and associated proteomes, and extended treatment rescues mitochondrial respiration in ApoE4 astrocytes. Taken together, our study provides a direct link between ApoE4-induced lysosomal cholesterol accumulation and abnormal oxidative phosphorylation. Lee, Hyein; Cho, Sukhee; Kim, Mi-Jin; Park, Yeo Jin; Cho, Eunji; Jo, Yeon Suk; Kim, Yong-Seok; Lee, Jung Yi; Thoudam, Themis; Woo, Seung-Hwa; Lee, Se-In; Jeon, Juyeong; Lee, Young-Sam; Suh, Byung-Chang; Yoon, Jong Hyuk; Go, Younghoon; Lee, In-Kyu; Seo, Jinsoo Daegu Gyeongbuk Inst Sci & Technol, Dept Brain Sci, Daegu 42988, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Leading Edge Res Ctr Drug Discovery & Dev Diabet &, Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Res Inst Aging & Metab, Daegu 41944, South Korea; Univ Sci & Technol, Korean Med Life Sci, Daejeon 34054, South Korea; Korea Inst Oriental Med, Korean Med Applicat Ctr, Daegu 41062, South Korea; Korea Brain Res Inst, Neurodegenerat Dis Res Grp, Daegu 41062, South Korea; Daegu Gyeongbuk Inst Sci & Technol, Dept New Biol, Daegu 42988, South Korea ; Seo, Jinsoo/AAD-4950-2019; thoudam, themis/ACM-3919-2022 57212057493; 55801815000; 58364690500; 57196349389; 55863428700; 57343806700; 57216975471; 57195563161; 57192905626; 57225025140; 57253049800; 58622080700; 56328278900; 7103193835; 57212513350; 55455882000; 36071537600; 7401783716 gotra827@kiom.re.kr;leei@knu.ac.kr;jsseo@dgist.ac.kr; CELL REPORTS CELL REP 2211-1247 42 10 SCIE CELL BIOLOGY 2023 7.5 17.3 2.29 2025-06-25 31 23 BRAIN AEROBIC GLYCOLYSIS; METHYL-BETA-CYCLODEXTRIN; ALZHEIMERS-DISEASE; PATTERNS; APOE ApoE4; CP: Cell biology; CP: Metabolism; glucose metabolism; human astrocytes; lysosomal cholesterol accumulation; mitophagy Alzheimer Disease; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Astrocytes; Cells, Cultured; Cholesterol; Humans; Induced Pluripotent Stem Cells; Oxidative Phosphorylation; apolipoprotein E3; apolipoprotein E4; cholesterol; apolipoprotein E; apolipoprotein E3; apolipoprotein E4; cholesterol; aged; animal cell; ApoE4 gene; Article; astrocyte; autophagy (cellular); cell damage; cell ultrastructure; cholesterol metabolism; clinical article; controlled study; female; glycolysis; human; human cell; induced pluripotent stem cell; lysosome; mitochondrial dynamics; mitochondrial respiration; mouse; nonhuman; oxidative phosphorylation; proteomics; very elderly; Alzheimer disease; astrocyte; cell culture; genetics; induced pluripotent stem cell; metabolism; oxidative phosphorylation English 2023 2023-10-31 10.1016/j.celrep.2023.113183 바로가기 바로가기 바로가기 바로가기
Article Comparison of Polarized Radiative Transfer Codes Used by the EHT Collaboration Interpretation of resolved polarized images of black holes by the Event Horizon Telescope (EHT) requires predictions of the polarized emission observable by an Earth-based instrument for a particular model of the black hole accretion system. Such predictions are generated by general relativistic radiative transfer (GRRT) codes, which integrate the equations of polarized radiative transfer in curved spacetime. A selection of ray-tracing GRRT codes used within the EHT Collaboration is evaluated for accuracy and consistency in producing a selection of test images, demonstrating that the various methods and implementations of radiative transfer calculations are highly consistent. When imaging an analytic accretion model, we find that all codes produce images similar within a pixel-wise normalized mean squared error (NMSE) of 0.012 in the worst case. When imaging a snapshot from a cell-based magnetohydrodynamic simulation, we find all test images to be similar within NMSEs of 0.02, 0.04, 0.04, and 0.12 in Stokes I, Q, U, and V, respectively. We additionally find the values of several image metrics relevant to published EHT results to be in agreement to much better precision than measurement uncertainties. Prather, Ben S.; Dexter, Jason; Moscibrodzka, Monika; Pu, Hung-Yi; Bronzwaer, Thomas; Davelaar, Jordy; Younsi, Ziri; Gammie, Charles F.; Gold, Roman; Wong, George N.; Akiyama, Kazunori; Alberdi, Antxon; Alef, Walter; Algaba, Juan Carlos; Anantua, Richard; Asada, Keiichi; Azulay, Rebecca; Bach, Uwe; Baczko, Anne-Kathrin; Ball, David; Balokovic, Mislav; Barrett, John; Bauboeck, Michi A.; Benson, Bradford; Bintley, Dan; Blackburn, Lindy; Blundell, Raymond L.; Bouman, Katherine C.; Bower, Geoffrey; Boyce, Hope; Bremer, Michael D.; Brinkerink, Christiaan; Brissenden, Roger; Britzen, Silke E.; Broderick, Avery; Broguiere, Dominique; Bustamante, Sandra; Byun, Do-Young E.; Carlstrom, John; Ceccobello, Chiara; Chael, Andrew; Chan, Chi-kwan O.; Chang, Dominic; Chatterjee, Koushik; Chatterjee, Shami; Chen, Ming-Tang; Chen, Yongjun; Cheng, Xiaopeng; Cho, Ilje; Christian, Pierre S.; Conroy, Nicholas E.; Conway, John M.; Cordes, James M.; Crawford, Thomas B.; Crew, Geoffrey; Cruz-Osorio, Alejandro; Cui, Yuzhu; De Laurentis, Mariafelicia; Deane, Roger; Dempsey, Jessica; Desvignes, Gregory; Dhruv, Vedant S.; Doeleman, Sheperd; Dougal, Sean A.; Dzib, Sergio P.; Eatough, Ralph; Emami, Razieh; Falcke, Heino; Farah, Joseph L.; Fish, Vincent; Fomalont, Ed; Ford, H. Alyson; Fraga-Encinas, Raquel T.; Freeman, William; Friberg, Per M.; Fromm, Christian; Fuentes, Antonio; Galison, Peter; Garcia, Roberto; Gentaz, Olivier; Georgiev, Boris; Goddi, Ciriaco I.; Gomez-Ruiz, Arturo; Gomez, Jose L.; Gu, Minfeng; Gurwell, Mark; Hada, Kazuhiro; Haggard, Daryl; Haworth, Kari H.; Hecht, Michael; Hesper, Ronald; Heumann, Dirk C.; Ho, Luis C.; Ho, Paul; Honma, Mareki; Huang, Chih-Wei L.; Huang, Lei H.; Hughes, David; Ikeda, Shiro; Impellizzeri, C. M. Violette; Inoue, Makoto; Issaoun, Sara J.; James, David T.; Jannuzi, Buell; Janssen, Michael; Jeter, Britton; Jiang, Wu; Jimenez-Rosales, Alejandra D.; Johnson, Michael; Jorstad, Svetlana V.; Joshi, Abhishek; Jung, Taehyun; Karami, Mansour; Karuppusamy, Ramesh; Kawashima, Tomohisa K.; Keating, Garrett; Kettenis, Mark; Kim, Dong-Jin; Kim, Jae-Young; Kim, Jongsoo; Kim, Junhan; Kino, Motoki; Koay, Jun Yi; Kocherlakota, Prashant; Kofuji, Yutaro; Koyama, Shoko; Kramer, Carsten; Kramer, Michael P.; Krichbaum, Thomas; Kuo, Cheng-Yu; La Bella, Noemi R.; Lauer, Tod; Lee, Daeyoung; Lee, Sang-Sung; Leung, Po Kin; Levis, Aviad; Li, Zhiyuan; Lico, Rocco; Lindahl, Greg; Lindqvist, Michael; Lisakov, Mikhail; Liu, Jun; Liu, Kuo; Liuzzo, Elisabetta; Lo, Wen-Ping P.; Lobanov, Andrei; Loinard, Laurent J.; Lonsdale, Colin; Lu, Ru-Sen R.; MacDonald, Nicholas; Mao, Jirong; Marchili, Nicola; Markoff, Sera P.; Marrone, Daniel P.; Marscher, Alan; Marti-Vidal, Ivan; Matsushita, Satoki D.; Matthews, Lynn; Medeiros, Lia M.; Menten, Karl; Michalik, Daniel; Mizuno, Izumi; Mizuno, Yosuke M.; Moran, James; Moriyama, Kotaro; Mueller, Cornelia; Mus, Alejandro; Musoke, Gibwa; Myserlis, Ioannis; Nadolski, Andrew; Nagai, Hiroshi M.; Nagar, Neil; Nakamura, Masanori; Narayan, Ramesh; Narayanan, Gopal; Natarajan, Iniyan; Nathanail, Antonios; Fuentes, Santiago Navarro; Neilsen, Joey; Neri, Roberto; Ni, Chunchong; Noutsos, Aristeidis A.; Nowak, Michael; Oh, Junghwan; Okino, Hiroki; Olivares, Hector N.; Ortiz-Leon, Gisela; Oyama, Tomoaki; oezel, Feryal; Palumbo, Daniel C. M.; Paraschos, Georgios Filippos; Park, Jongho; Parsons, Harriet; Patel, Nimesh; Pen, Ue-Li W.; Pesce, Dominic; Pietu, Vincent; Plambeck, Richard; PopStefanija, Aleksandar; Porth, Oliver M.; Poetzl, Felix A.; Preciado-Lopez, Jorge; Psaltis, Dimitrios; Ramakrishnan, Venkatessh; Rao, Ramprasad G.; Rawlings, Mark W.; Raymond, Alexander; Rezzolla, Luciano; Ricarte, Angelo; Ripperda, Bart; Roelofs, Freek; Rogers, Alan; Ros, Eduardo; Romero-Canizales, Cristina; Roshanineshat, Arash; Rottmann, Helge L.; Roy, Alan; Ruiz, Ignacio; Ruszczyk, Chet; Rygl, Kazi L. J.; Sanchez, Salvador; Sanchez-Argueelles, David; Sanchez-Portal, Miguel; Sasada, Mahito; Satapathy, Kaushik; Savolainen, Tuomas; Schloerb, F. Peter; Schonfeld, Jonathan; Schuster, Karl-Friedrich; Shao, Lijing; Shen, Zhiqiang; Small, Des; Sohn, Bong Won; SooHoo, Jason; Souccar, Kamal; Sun, He; Tazaki, Fumie J.; Tetarenko, Alexandra; Tiede, Paul; Tilanus, Remo P. J.; Titus, Michael; Torne, Pablo; Traianou, Efthalia; Trent, Tyler; Trippe, Sascha; Turk, Matthew; van Bemmel, Ilse; van Langevelde, Huib Jan R.; van Rossum, Daniel; Vos, Jesse; Wagner, Jan; Ward-Thompson, Derek; Wardle, John; Weintroub, Jonathan; Wex, Norbert; Wharton, Robert; Wielgus, Maciek; Wiik, Kaj; Witzel, Gunther F.; Wondrak, Michael; Wu, Qingwen; Yamaguchi, Paul; Yfantis, Aristomenis; Yoon, Doosoo; Young, Andre; Young, Ken; Yu, Wei; Yuan, Feng; Yuan, Ye-Fei; Zensus, J. Anton; Zhang, Shuo; Zhao, Guang-Yao; Zhao, Shan-Shan Los Alamos Natl Lab, CCS 2, POB 1663, Los Alamos, NM 87545 USA; Univ Colorado, JILA, Boulder, CO 80309 USA; Univ Colorado, Dept Astrophys & Planetary Sci, Boulder, CO 80309 USA; Radboud Univ Nijmegen, IMAPP, Dept Astrophys, POB 9010, NL-6500 GL Nijmegen, Netherlands; Natl Taiwan Normal Univ, Dept Phys, 88,Sect 4,Tingzhou Rd, Taipei 116, Taiwan; Natl Taiwan Normal Univ, Ctr Astron & Gravitat, 88,Sect 4,Tingzhou Rd, Taipei 116, Taiwan; Acad Sinica, Inst Astron & Astrophys, 11F Astron Math Bldg,AS NTU 1,Sect 4,Roosevelt Rd, Taipei 10617, Taiwan; Columbia Univ, Dept Astron, 550 W 120th St, New York, NY 10027 USA; Columbia Univ, Columbia Astrophys Lab, 550 W 120th St, New York, NY 10027 USA; Flatiron Inst, Ctr Computat Astrophys, 162 Fifth Ave, New York, NY 10010 USA; Radboud Univ Nijmegen, Inst Math Astrophys & Particle Phys IMAPP, Dept Astrophys, POB 9010, NL-6500 GL Nijmegen, Netherlands; Univ Coll London, Mullard Space Sci Lab, Dorking RH5 6NT, Surrey, England; Goethe Univ Frankfurt, Inst Theoret Phys, Max von Laue Str 1, D-60438 Frankfurt, Germany; Univ Illinois, Dept Phys, 1110 West Green St, Urbana, IL 61801 USA; Univ Illinois, Dept Astron, 1002 West Green St, Urbana, IL 61801 USA; Univ Illinois, NCSA, 1205 W Clark St, Urbana, IL 61801 USA; Univ Southern Denmark, CP3 Origins, Campusvej 55, DK-5230 Odense M, Denmark; Inst Adv Study, Sch Nat Sci, 1 Einstein Dr, Princeton, NJ 08540 USA; Princeton Univ, Princeton Grav Initiat, Princeton, NJ 08544 USA; MIT, Haystack Observ, 99 Millstone Rd, Westford, MA 01886 USA; Natl Astron Observ Japan, 2-21-1 Osawa, Mitaka, Tokyo 1818588, Japan; Harvard Univ, Black Hole Initiat, 20 Garden St, Cambridge, MA 02138 USA; CSIC, Inst Astrofis Andalucia, Glorieta Astron S-N, E-18008 Granada, Spain; Max Planck Inst Radioastron, Hugel 69, D-53121 Bonn, Germany; Univ Malaya, Dept Phys, Fac Sci, Kuala Lumpur 50603, Malaysia; Harvard Smithsonian Ctr Astrophys, 60 Garden St, Cambridge, MA 02138 USA; Univ Texas San Antonio, Dept Phys & Astron, One UTSA Circle, San Antonio, TX 78249 USA; Univ Valencia, Dept Astron & Astrofis, C Dr Moliner 50, E-46100 Valencia, Spain; Univ Valencia, Observ Astron, C Catedratico Jose Beltran 2, E-46980 Valencia, Spain; Univ Arizona, Steward Observ, 933 N Cherry Ave, Tucson, AZ 85721 USA; Univ Arizona, Dept Astron, 933 N Cherry Ave, Tucson, AZ 85721 USA; Yale Univ, Yale Ctr Astron & Astrophys, 52 Hillhouse Ave, New Haven, CT 06511 USA; Fermilab Natl Accelerator Lab, MS209,POB 500, Batavia, IL 60510 USA; Univ Chicago, Dept Astron & Astrophys, 5640 South Ellis Ave, Chicago, IL 60637 USA; East Asian Observ, 660 N Aohoku Pl, Hilo, HI 96720 USA; James Clerk Maxwell Telescope JCMT, 660 N Aohoku Pl, Hilo, HI 96720 USA; CALTECH, 1200 East Calif Blvd, Pasadena, CA 91125 USA; Acad Sinica, Inst Astron & Astrophys, 645 N Aohoku Pl, Hilo, HI 96720 USA; Univ Hawaii, Dept Phys & Astron, 2505 Correa Rd, Honolulu, HI 96822 USA; McGill Univ, Dept Phys, 3600 Rue Univ, Montreal, PQ H3A 2T8, Canada; McGill Univ, McGill Space Inst, 3550 Rue Univ, Montreal, PQ H3A 2A7, Canada; Inst Radioastron Millimetr IRAM, 300 Rue Piscine, F-38406 St Martin Dheres, France; Perimeter Inst Theoret Phys, 31 Caroline St North, Waterloo, ON N2L 2Y5, Canada; Univ Waterloo, Dept Phys & Astron, 200 Univ Ave West, Waterloo, ON N2L 3G1, Canada; Univ Waterloo, Waterloo Ctr Astrophys, Waterloo, ON N2L 3G1, Canada; Univ Massachusetts, Dept Astron, Amherst, MA 01003 USA; Korea Astron & Space Sci Inst, Daedeok Daero 776, Daejeon 34055, South Korea; Univ Sci & Technol, Gajeong Ro 217, Daejeon 34113, South Korea; Univ Chicago, Kavli Inst Cosmol Phys, 5640 South Ellis Ave, Chicago, IL 60637 USA; Univ Chicago, Dept Phys, 5720 South Ellis Ave, Chicago, IL 60637 USA; Univ Chicago, Enrico Fermi Inst, 5640 South Ellis Ave, Chicago, IL 60637 USA; Chalmers Univ Technol, Onsala Space Observ, Dept Space Earth & Environm, SE-43992 Onsala, Sweden; Princeton Univ, Princeton Grav Initiat, Jadwin Hall, Princeton, NJ 08544 USA; Univ Arizona, Data Sci Inst, 1230 N Cherry Ave, Tucson, AZ 85721 USA; Univ Arizona, Program Appl Math, 617 N Santa Rita, Tucson, AZ 85721 USA; Cornell Univ, Cornell Ctr Astrophys & Planetary Sci, Ithaca, NY 14853 USA; Chinese Acad Sci, Shanghai Astron Observ, 80 Nandan Rd, Shanghai 200030, Peoples R China; Chinese Acad Sci, Key Lab Radio Astron, Nanjing 210008, Peoples R China; Fairfield Univ, Dept Phys, 1073 North Benson Rd, Fairfield, CT 06824 USA; Zhejiang Lab, Res Ctr Intelligent Comp Platforms, Hangzhou 311100, Peoples R China; Shanghai Jiao Tong Univ, Tsung Dao Lee Inst, Shengrong Rd 520, Shanghai 201210, Peoples R China; Univ Napoli Federico II, Dipartimento Fis Pancini, Edificio G,Via Cinthia, I-80126 Naples, Italy; INFN, Sez Napoli, Edificio G,Via Cinthia, I-80126 Naples, Italy; Univ Witwatersrand, Wits Ctr Astrophys, 1 Jan Smuts Ave, ZA-2050 Johannesburg, South Africa; Univ Pretoria, Dept Phys, ZA-0028 Pretoria, South Africa; Rhodes Univ, Dept Phys & Elect, Ctr Radio Astron Tech & Technol, ZA-6140 Makhanda, South Africa; ASTRON, Oude Hoogeveensedijk 4, NL-7991 PD Dwingeloo, Netherlands; Univ Paris, Sorbonne Univ, Observ Paris, LESIA,Univ PSL,CNRS, 5 Pl Jules Janssen, F-92195 Meudon, France; Chinese Acad Sci, Natl Astron Observ, 20A Datun Rd, Beijing 100101, Peoples R China; Las Cumbres Observ, 6740 Cortona Dr,Suite 102, Goleta, CA 93117 USA; Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA; Natl Radio Astron Observ, 520 Edgemont Rd, Charlottesville, VA 22903 USA; MIT, Dept Elect Engn & Comp Sci, 32-D476,77 Massachusetts Ave, Cambridge, MA 02142 USA; Google Res, 355 Main St, Cambridge, MA 02142 USA; Univ Wurzburg, Inst Theoret Phys & Astrophys, Emil Fischer Str 31, D-97074 Wurzburg, Germany; Harvard Univ, Dept Hist Sci, Cambridge, MA 02138 USA; Harvard Univ, Dept Phys, Cambridge, MA 02138 USA; Univ Sao Paulo, Inst Astron Geofis & Ciencias Atmosfer, Dept Astron, BR-05508090 Sao Paulo, SP, Brazil; Univ Cagliari, Dipartimento Fis, SP Monserrato Sestu Km 0-7, I-09042 Monserrato, Italy; INAF, Osservatorio Astron Cagliari, Via Sci 5, I-09047 Selargius, CA, Italy; INFN, Sez Cagliari, Cittadella Univ, I-09042 Monserrato, CA, Italy; Inst Nacl Astrofis Opt & Electr, Apartado Postal 51 & 216, Puebla Pue 72000, Mexico; Consejo Nacl Ciencia & Technol, Ave Insurgentes 1582, Mexico City 03940, DF, Mexico; Chinese Acad Sci, Key Lab Res Galaxies & Cosmol, Shanghai 200030, Peoples R China; Natl Astron Observ Japan, Mizusawa VLBI Observ, 2-12 Hoshigaoka, Mizusawa, Iwate 0230861, Japan; Grad Univ Adv Studies SOKENDAI, Dept Astron Sci, 2-21-1 Osawa, Mitaka, Tokyo 1818588, Japan; Univ Groningen, NOVA Sub Mm Instrumentat Grp, Kapteyn Astron Inst, Landleven 12, NL-9747 AD Groningen, Netherlands; Peking Univ, Sch Phys, Dept Astron, Beijing 100871, Peoples R China; Peking Univ, Kavli Inst Astron & Astrophys, Beijing 100871, Peoples R China; Univ Tokyo, Grad Sch Sci, Dept Astron, 7-3-1 Hongo,Bunkyo Ku, Tokyo 1130033, Japan; Inst Stat Math, 10-3 Midori Cho, Tachikawa, Tokyo 1908562, Japan; Grad Univ Adv Studies SOKENDAI, Dept Stat Sci, 10-3 Midori Cho, Tachikawa, Tokyo 1908562, Japan; Univ Tokyo, Kavli Inst Phys & Math Universe, 1-5 Kashiwanoha, Kashiwa, Chiba 2778583, Japan; Leiden Univ, Leiden Observ, Postbus 2300, NL-9513 RA Leiden, Netherlands; Georgia Inst Technol, Sch Phys, 837 State St NW, Atlanta, GA 30332 USA; ASTRAVEO LLC, POB 1668, Gloucester, MA 01931 USA; Boston Univ, Inst Astrophys Res, 725 Commonwealth Ave, Boston, MA 02215 USA; Univ Tokyo, Inst Cosm Ray Res, 5-1-5 Kashiwanoha, Kashiwa, Chiba 2778582, Japan; Joint Inst VLBI ERIC JIVE, Oude Hoogeveensedijk 4, NL-7991 PD Dwingeloo, Netherlands; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 702701, South Korea; Kogakuin Univ Technol & Engn, Acad Support Ctr, 2665-1 Nakano, Hachioji, Tokyo 1920015, Japan; Niigata Univ, 8050 Ikarashi Nino Cho,Nishi Ku, Niigata 9502181, Japan; Natl Sun Yat Sen Univ, Dept Phys, 70 Lien Hai Rd, Kaosiung City 80424, Taiwan; Natl Opt Astron Observ, 950 N Cherry Ave, Tucson, AZ 85719 USA; Chinese Univ Hong Kong, Dept Phys, Shatin, Hong Kong, Peoples R China; Nanjing Univ, Sch Astron & Space Sci, Nanjing 210023, Peoples R China; Nanjing Univ, Key Lab Modern Astron & Astrophys, Nanjing 210023, Peoples R China; INAF, Ist Radioastron, Via P Gobetti 101, I-40129 Bologna, Italy; Italian ALMA Reg Ctr, Via P Gobetti 101, I-40129 Bologna, Italy; Natl Taiwan Univ, Dept Phys, 1,Sect 4,Roosevelt Rd, Taipei 10617, Taiwan; Univ Nacl Autonoma Mexico, Inst Radioastron & Astrofis, Morelia 58089, Michoacan, Mexico; Univ Nacl Autonoma Mexico, Inst Astron, Apdo Postal 70-264, Mexico City, DF, Mexico; Chinese Acad Sci, Yunnan Observ, Kunming 650011, Yunnan, Peoples R China; Chinese Acad Sci, Ctr Astron Mega Sci, 20A Datun Rd, Beijing 100012, Peoples R China; Chinese Acad Sci, Key Lab Struct & Evolut Celestial Objects, Kunming 650011, Yunnan, Peoples R China; Univ Amsterdam, Astron Inst Anton Pannekoek, Sci Pk 904, NL-1098 XH Amsterdam, Netherlands; Univ Amsterdam, Gravitat & Astroparticle Phys Amsterdam GRAPPA In, Sci Pk 904, NL-1098 XH Amsterdam, Netherlands; European Space Res & Technol Ctr ESA ESTEC, Sci Support Off, Directorate Sci, Keplerlaan 1, NL-2201 AZ Noordwijk, Netherlands; Shanghai Jiao Tong Univ, Sch Phys & Astron, 800 Dongchuan Rd, Shanghai 200240, Peoples R China; Inst Radioastron Millimetr IRAM, Ave Divina Pastora 7,Local 20, E-18012 Granada, Spain; Univ Concepcion, Dept Astron, Casilla 160-C, Concepcion, Chile; Hachinohe Coll, Natl Inst Technol, 16-1 Uwanotai, Hachinohe, Aomori 0391192, Japan; Natl & Kapodistrian Univ Athens, Dept Phys, GR-15783 Zografos, Greece; Villanova Univ, Dept Phys, 800 Lancaster Ave, Villanova, PA 19085 USA; Washington Univ, Dept Phys, CB 1105, St Louis, MO 63130 USA; Sejong Univ, 209 Neungdong Ro, Seoul, South Korea; Univ Toronto, Canadian Inst Theoret Astrophys, 60 St George St, Toronto, ON M5S 3H8, Canada; Univ Toronto, Dunlap Inst Astron & Astrophys, 50 St George St, Toronto, ON M5S 3H4, Canada; Canadian Inst Adv Res, 180 Dundas St West, Toronto, ON M5G 1Z8, Canada; Univ Calif Berkeley, Radio Astron Lab, Berkeley, CA 94720 USA; Fdn Res & Technol Hellas, Inst Astrophys, Iraklion 7110, Greece; Univ Turku, Finnish Ctr Astron, ESO, FI-20014 Turku, Finland; Aalto Univ, Metsahovi Radio Observ, Metsahovintie 114, FI-02540 Kylmala, Finland; Gemini Observ, NSF NOIRLab, 670 N Aohoku Pl, Hilo, HI 96720 USA; Frankfurt Inst Adv Studies, Ruth Moufang Str 1, D-60438 Frankfurt, Germany; Trinity Coll Dublin, Sch Math, Dublin 2, Ireland; Princeton Univ, Dept Astrophys Sci, Peyton Hall, Princeton, NJ 08544 USA; Tokyo Inst Technol, Dept Phys, 2-12-1 Ookayama,Meguro Ku, Tokyo 1528551, Japan; Hiroshima Univ, Hiroshima Astrophys Sci Ctr, 1-3-1 Kagamiyama, Higashihiroshima, Hiroshima 7398526, Japan; Aalto Univ, Dept Elect & Nanoengn, PL 15500, FI-00076 Aalto, Finland; Yonsei Univ, Dept Astron, Yonsei Ro 50, Seoul 03722, South Korea; Texas Tech Univ, Dept Phys & Astron, Lubbock, TX 79409 USA; Netherlands Org Sci Res NWO, Postbus 93138, NL-2509 AC The Hague, Netherlands; Seoul Natl Univ, Dept Phys & Astron, Seoul 08826, South Korea; Univ New Mexico, Dept Phys & Astron, Albuquerque, NM 87131 USA; Univ Cent Lancashire, Jeremiah Horrocks Inst, Preston PR1 2HE, Lancs, England; Brandeis Univ, Dept Phys, 415 South St, Waltham, MA 02453 USA; Univ Turku, Dept Phys & Astron, Tuorla Observ, Turku, Finland; Radboud Univ Nijmegen, Nijmegen, Netherlands; Huazhong Univ Sci & Technol, Sch Phys, Wuhan 430074, Hubei, Peoples R China; Univ Chinese Acad Sci, Sch Astron & Space Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China; Univ Sci & Technol China, Dept Astron, Hefei 230026, Peoples R China; Bard Coll, 30 Campus Rd, Annandale on Hudson, NY 12504 USA Falcke, Heino/H-5262-2012; Nguyen, Chi/GZG-5146-2022; Loinard, Laurent/MCX-8116-2025; Goddi, Ciriaco/AAN-4033-2021; Cruz Osorio, Alejandro/GQQ-8823-2022; Chen, Ming-Tang/ABC-7461-2020; Yu, wei/Y-9396-2018; Li, Juanjuan/J-3914-2017; ho, paul/AAZ-5108-2020; Park, Jongho/JFB-2747-2023; Lico, Rocco/L-8308-2019; Lee, Sang-Sung/AFS-2722-2022; Ramakrishnan, Venkatessh/C-8628-2017; Wong, George/AAL-1016-2021; HUANG, LING/HTR-1819-2023; Liu, Kuo/AAM-1431-2021; Olivares Sanchez, Hector Raul/KWU-1646-2024; Lisakov, Mikhail/M-6034-2013; Azulay, Rebecca/U-2560-2017; Lee, Dae-Young/AAI-6981-2020; Zamorano, Jose/ABU-6635-2022; Matsushita, Satoki/ABD-5562-2020; Schuster, Karling/JMP-9441-2023; Ros, Eduardo/B-1014-2015; Moriyama, Kotaro/NGQ-8643-2025; Algaba, Juan Carlos/AAB-4526-2022; Rao, Ramprasad/L-2115-2017; Li, Zhiyuan/GWM-6492-2022; Chatterjee, Shami/AAE-8374-2022; Myserlis, Ioannis/MCY-5944-2025; Gold, Roman/AAX-5851-2021; Ikeda, Shiro/E-1736-2016; Torne, Pablo/MIP-4319-2025; Kawashima, Tomohisa/GYD-8953-2022; Bower, Geoffrey/ABC-8386-2020; 浅田圭一, Keiichi/ABC-2456-2020; Shao, Lijing/GRO-6046-2022; Lobanov, Andrei/G-5891-2014; Ceccobello, Chiara/AAD-4283-2022; huang, lei/GQP-8739-2022; Lisakov, Mikhail/JAX-3277-2023; Kino, Motoki/LQK-9129-2024; Wagner, Jan/LTZ-8501-2024; Turk, Matthew/GXV-9589-2022; Kim, Junhan/LTZ-1683-2024; Cheng, Xiaopeng/ABX-5356-2022; Kim, Dong Jin/JMR-1090-2023; Impellizzeri, Violette/JQW-3813-2023; Pesce, Dominic/AAX-6358-2021; Olivares, Hector/KWU-1646-2024; Kramer, Michael/KLY-3270-2024; Koay, Jun/E-4952-2015; Bach, Udo/F-3880-2012; Cheng, Hok-Chuen/GNP-8341-2022; Ho, Paul/AAZ-5108-2020; Rezzolla, Luciano/JPK-1036-2023; shuo, zhang/KGM-7804-2024; nagar, neil/AAG-4543-2020; Barrett, John/K-8867-2014; 韓之強, Chih/AAZ-8498-2020; Wielgus, Maciek/JEF-6647-2023; Sanchez, David/KIH-3142-2024; Kim, Jae-Young/IUO-6466-2023; Pen, Ue-Li/AAX-6083-2021; Fuentes, Antonio/R-3900-2019; Sasada, Mahito/ABD-5766-2020; Baczko, Anne-Kathrin/AAW-2724-2020 57208317879; 7007145665; 57203337908; 56021813700; 55845982300; 57190763305; 55347813900; 7003953073; 55504461000; 57208320165; 55669706400; 7004247728; 6603338811; 25640916000; 34876318600; 7102181737; 55974067100; 8356678200; 57191172071; 57191854254; 55441118000; 57221919962; 55279774300; 43360904200; 6508166420; 35271380400; 7005148075; 36627851000; 7006319230; 56514949800; 55348923700; 55789158500; 6701852507; 6602806448; 7005699469; 12805385500; 57208321725; 57203026080; 35276941600; 50660994600; 55324722200; 36984595000; 57223840952; 56714950900; 35500782800; 57137032900; 55721215400; 57194012321; 57203071154; 36918061000; 57740566800; 7402605418; 7102087612; 55432044800; 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7102531000; 26666313200; 57190127327; 36816303500; 8791509900; 57208321142; 14012249000; 18435453100; 57196907740; 54389941800; 6602969503; 23986018200; 57344402000; 7003371610; 55663305800; 57192669640; 55952822800; 25652194300; 7403324447; 57208321653; 25628978700; 44561693800; 6602795601; 57192429990; 43361892500; 56658751100; 56657947900; 6701628482; 7007019201; 57190767230; 57204824800; 57208316147; 8559107900; 24077308500; 6602323834; 6603776865; 36057630500; 57220895149; 55236056100; 7004002583; 36613480200; 23487579300; 6603048295; 55262937300; 52164611300; 7004299975; 24833754300; 57189852229; 57207446777; 56721395200; 57779474100; 54384535700; 56221262400; 7402601128; 55804393100; 57203725419; 35185850600; 7004929291; 55767566800; 55478882500; 55877039000 bprather@lanl.gov; ASTROPHYSICAL JOURNAL ASTROPHYS J 0004-637X 1538-4357 950 1 SCIE ASTRONOMY & ASTROPHYSICS 2023 4.8 17.3 2.02 2025-06-25 18 17 M87 EVENT HORIZON; TELESCOPE RESULTS. VI.; ACCRETING BLACK-HOLES; A-ASTERISK; EMISSION; SHADOW; FLOWS; I. English 2023 2023-06-01 10.3847/1538-4357/acc586 바로가기 바로가기 바로가기 바로가기
Article Deficit of Hot Dust in Low-redshift Active Galactic Nuclei We assemble a broadband spectral energy distribution (SED) ranging from the optical to the mid-infrared of nearby active galactic nuclei (AGNs) at z < 0.4. The SED fitting analysis is performed using semiempirical templates derived from Palomar-Green quasars to classify the sample into normal, warm-dust-deficient (WDD), and hot-dust-deficient (HDD) AGNs. Kolmogorov-Smirnov tests reveal that HDD AGNs exhibit higher AGN luminosity on average than normal and WDD AGNs. The HDD fraction, on the other hand, is only weakly correlated with the black hole mass and inversely correlated with the Eddington ratio. By fixing the other parameters, we conclude that the HDD fraction is primarily connected with the AGN luminosity. This implies that there is a causal connection between the covering factor of the hot dust component and AGN luminosity, possibly due to the sublimation of the innermost dust or the thickening of the intervening gas in the broad-line region. Analysis of the outflow properties traced by the wing of [O iii]& lambda;5007 suggests that outflows may be related to the formation and maintenance of the hot dust component. Finally, we demonstrate through comparison with previous studies that the classification of HDD AGNs requires careful subtraction of the host galaxy light. Son, Suyeon; Kim, Minjin; Ho, Luis C. Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 702701, South Korea; Peking Univ, Kavli Inst Astron & Astrophys, Beijing 100871, Peoples R China; Peking Univ, Sch Phys, Dept Astron, Beijing 100871, Peoples R China Kim, Minjin/AAU-9910-2020 57226328130; 56898213300; 57225302746 mkim.astro@gmail.com; ASTROPHYSICAL JOURNAL ASTROPHYS J 0004-637X 1538-4357 953 2 SCIE ASTRONOMY & ASTROPHYSICS 2023 4.8 17.3 0.59 2025-06-25 5 5 SPECTRAL ENERGY-DISTRIBUTIONS; EMISSION-LINE REGION; BLACK-HOLES; REVERBERATION MEASUREMENTS; STELLAR POPULATION; INFRARED-EMISSION; INNER RADIUS; RADIATION PRESSURE; SEYFERT-GALAXIES; COVERING FACTOR English 2023 2023-08-01 10.3847/1538-4357/ace165 바로가기 바로가기 바로가기 바로가기
Article Double SSA spectrum and magnetic field strength of the FSRQ 3C 454.3 We present the results of a radio multifrequency (3-340 GHz) study of the blazar 3C 454.3. After subtracting the quiescent spectrum corresponding to optically thin emission, we found two individual synchrotron self-absorption (SSA) features in the wide-band spectrum. The one SSA had a relatively low turnover frequency (nu(m)) in the range of 3-37 GHz (lower nu(m) SSA spectrum, LSS), and the other one had a relatively high nu(m) of 55-124 GHz (higher nu(m) SSA spectrum, HSS). Using the SSA parameters, we estimated B-field strengths at the surface where optical depth tau = 1. The estimated B-field strengths were > 7 and > 0.2 mG for the LSS and HSS, respectively. The LSS-emitting region was magnetically dominated before the 2014 June gamma-ray flare. The quasi-stationary component (C), similar to 0.6 mas apart from the 43 -GHz radio core, became brighter than the core with decreasing observing frequency, and we found that component C was related to the LSS. A decrease in jet width was found near component C. As a moving component, K14 approached component C, and the flux density of the component was enhanced while the angular size decreased. The high intrinsic brightness temperature in the fluid frame was obtained as T-B,T- int approximate to (7.0 +/- 1.0) x 10(11) K from the jet component after the 2015 August.-ray flare, suggesting that component C is a high-energy emitting region. The observed local minimum of jet width and re-brightening behaviour suggest a possible recollimation shock in component C. Jeong, Hyeon-Woo; Lee, Sang-Sung; Cheong, Whee Yeon; Kim, Jae-Young; Lee, Jee Won; Kang, Sincheol; Kim, Sang-Hyun; Rani, B.; Park, Jongho; Gurwell, Mark A. Univ Sci & Technol, Astron & Space Sci, 217 Gajeong Ro, Daejeon 34113, South Korea; Korea Astron & Space Sci Inst, 776 Daedeok Daero, Daejeon 34055, South Korea; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 702701, South Korea; Max Planck Inst Radioastron, Auf Hugel 69, D-53121 Bonn, Germany; NASA Goddard Space Flight Ctr, Greenbelt, MD 20771 USA; Amer Univ, Dept Phys, Washington, DC 20016 USA; Ctr Astrophys Harvard & Smithsonian, 60 Garden St, Cambridge, MA 02138 USA Lee, Sang-Sung/AFS-2722-2022; Jeong, Hyeon Woo/HTM-2917-2023; Park, Jongho/JFB-2747-2023; Cheong, Whee Yeon/KCZ-2228-2024; Kim, Sang-hyun/C-1811-2011; Kim, Jae-Young/IUO-6466-2023 58260672200; 37056945900; 58150566100; 57211836467; 55870740000; 56023283900; 57219655175; 36125334100; 56953647500; 6602556944 sslee@kasi.re.kr; MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY MON NOT R ASTRON SOC 0035-8711 1365-2966 523 4 SCIE ASTRONOMY & ASTROPHYSICS 2023 4.8 17.3 0.36 2025-06-25 3 3 galaxies: active; galaxies: jets; quasars: individual: 3C 454.3; radio continuum: galaxies ACTIVE GALACTIC NUCLEI; PARSEC-SCALE JETS; GAMMA-RAY BLAZARS; CTA 102; RECOLLIMATION SHOCK; KINEMATICS ANALYSIS; FLUX-DENSITY; RADIO FLARE; CORE-SHIFT; FERMI ERA galaxies: active; galaxies: jets; quasars: individual: 3C 454.3; radio continuum: galaxies Absorption spectroscopy; Galaxies; B-fields; Component C; Field strengths; Galaxies active; Galaxies jets; Magnetic field strengths; Quasar: individual: 3c 454.3; Quasars: individual; Radio continuum: galaxies; Self absorption; Gamma rays English 2023 2023-06-22 10.1093/mnras/stad1736 바로가기 바로가기 바로가기 바로가기
Article Estimators of Bolometric Luminosity and Black Hole Mass with Mid-infrared Continuum Luminosities for Dust-obscured Quasars: Prevalence of Dust-obscured SDSS Quasars We present bolometric luminosity (L bol) and black hole (BH) mass (M BH) estimators based on mid-infrared (MIR) continuum luminosity (hereafter, L MIR) that are measured from infrared (IR) photometric data. The L MIR-based estimators are relatively immune from dust extinction effects, hence they can be used for dust-obscured quasars. To derive the L bol and M BH estimators, we use unobscured quasars selected from the Sloan Digital Sky Survey (SDSS) quasar catalog, which have wide ranges of L bol (1044.62-1046.16 erg s-1) and M BH (107.14-109.69 M & ODOT;). We find empirical relations between (i) continuum luminosity at 5100 & ANGS; (hereafter, L5100) and L MIR; (ii) L bol and L MIR. Using these relations, we derive the L MIR-based L bol and M BH estimators. We find that our estimators allow the determination of L bol and M BH at an accuracy of & SIM;0.2 dex against the fiducial estimates based on the optical properties of the unobscured quasars. We apply the L MIR-based estimators to SDSS quasars at z & LSIM; 0.5 including obscured ones. The ratios of L bol from the L MIR-based estimators to those from the optical luminosity-based estimators become larger with the amount of the dust extinction, and a non-negligible fraction (& SIM;15%) of the SDSS quasars exhibits ratios greater than 1.5. This result suggests that dust extinction can significantly affect physical parameter derivations even for SDSS quasars, and that dust extinction needs to be carefully taken into account when deriving quasar properties. Kim, Dohyeong; Im, Myungshin; Kim, Minjin; Kim, Yongjung; Shin, Suhyun; Shim, Hyunjin; Song, Hyunmi Pusan Natl Univ, Dept Earth Sci, Busan 46241, South Korea; Seoul Natl Univ, Dept Phys & Astron, Astron Program, Seoul 08826, South Korea; Seoul Natl Univ, SNU Astron Res Ctr SNU ARC, Dept Phys & Astron, Astron Program, Seoul 08826, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Dept Astron & Atmospher Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Earth Sci Educ, 80 Daehak Ro, Daegu 41566, South Korea; Chungnam Natl Univ, Dept Astron & Space Sci, 99 Daehak Ro, Daejeon 34134, South Korea ; , Yong Jung Kim/JRW-0681-2023; Kim, Minjin/AAU-9910-2020; Shim, Hyunjin/LZI-7486-2025; Im, Myungshin/B-3436-2013 55574223678; 7004267711; 56898213300; 59622148200; 57205483501; 14061137700; 35749280400 myungshin.im@gmail.com; ASTROPHYSICAL JOURNAL ASTROPHYS J 0004-637X 1538-4357 954 2 SCIE ASTRONOMY & ASTROPHYSICS 2023 4.8 17.3 1.07 2025-06-25 9 9 ACTIVE GALACTIC NUCLEI; SPECTRAL ENERGY-DISTRIBUTIONS; INFRARED-SURVEY-EXPLORER; HOT-DUST; GALAXY MERGERS; RED QUASARS; REVERBERATION MEASUREMENTS; ELLIPTIC GALAXIES; EMISSION-LINE; SKY English 2023 2023-09-01 10.3847/1538-4357/aceb5e 바로가기 바로가기 바로가기 바로가기
Article Feasibility study for the automatic surgical planning method based on statistical model PurposeIn this study, we proposed establishing an automatic computer-assisted surgical planning approach based on average population models.MethodsWe built the average population models from humerus datasets using the Advanced Normalization Toolkits (ANTs) and Shapeworks. Experiments include (1) evaluation of the average population models before surgical planning and (2) validation of the average population models in the context of predicting clinical landmarks on the humerus from the new dataset that was not involved in the process of building the average population model. The evaluation experiment consists of explained variation and distance model. The validation experiment calculated the root-mean-square error (RMSE) between the expert-determined clinical ground truths and the landmarks transferred from the average population model to the new dataset. The evaluation results and validation results when using the templates built from ANTs were compared to when using the mean shape generated from Shapeworks.ResultsThe average population models predicted clinical locations on the new dataset with acceptable errors when compared to the ground truth determined by an expert. However, the templates built from ANTs present better accuracy in landmark prediction when compared to the mean shape built from the Shapeworks.ConclusionThe average population model could be utilized to assist anatomical landmarks checking automatically and following surgical decisions for new patients who are not involved in the dataset used to generate the average population model. Nguyen, Hang Phuong; Lee, Hyun-Joo; Kim, Sungmin Univ Ulsan, Dept Elect Elect & Comp Engn, Ulsan, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthopaed Surg, Daegu, South Africa Lee, Hyun Joo/GVU-6347-2022 57450084300; 58838750100; 57835343800 sungminkim@ulsan.ac.kr; JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH J ORTHOP SURG RES 1749-799X 18 1 SCIE ORTHOPEDICS 2023 2.8 17.3 0.29 2025-06-25 2 1 Template; Statistical shape model; Computer-assisted surgical planning; Clinical decision support SHAPE MODELS; MRI; REGISTRATION Clinical decision support; Computer-assisted surgical planning; Statistical shape model; Template Feasibility Studies; Humans; Humerus; Models, Statistical; feasibility study; human; humerus; statistical model; surgery English 2023 2023-06-01 10.1186/s13018-023-03870-x 바로가기 바로가기 바로가기 바로가기
Article First BISTRO Observations of the Dark Cloud Taurus L1495A-B10: The Role of the Magnetic Field in the Earliest Stages of Low-mass Star Formation We present BISTRO Survey 850 mu m dust emission polarization observations of the L1495A-B10 region of the Taurus molecular cloud, taken at the James Clerk Maxwell Telescope (JCMT). We observe a roughly triangular network of dense filaments. We detect nine of the dense starless cores embedded within these filaments in polarization, finding that the plane-of-sky orientation of the core-scale magnetic field lies roughly perpendicular to the filaments in almost all cases. We also find that the large-scale magnetic field orientation measured by Planck is not correlated with any of the core or filament structures, except in the case of the lowest-density core. We propose a scenario for early prestellar evolution that is both an extension to, and consistent with, previous models, introducing an additional evolutionary transitional stage between field-dominated and matter-dominated evolution, observed here for the first time. In this scenario, the cloud collapses first to a sheet-like structure. Uniquely, we appear to be seeing this sheet almost face on. The sheet fragments into filaments, which in turn form cores. However, the material must reach a certain critical density before the evolution changes from being field dominated to being matter dominated. We measure the sheet surface density and the magnetic field strength at that transition for the first time and show consistency with an analytical prediction that had previously gone untested for over 50 yr. Ward-Thompson, Derek; Karoly, Janik; Pattle, Kate; Whitworth., Anthony; Kirk, Jason; Berry, David; Bastien, Pierre; Ching, Tao-Chung; Coude, Simon; Hwang, Jihye; Kwon, Woojin; Soam, Archana; Wang, Jia-Wei; Hasegawa, Tetsuo; Lai, Shih-Ping; Qiu, Keping; Arzoumanian, Doris; Bourke, Tyler L.; Byun, Do-Young; Chen, Huei-Ru Vivien; Chen, Wen Ping; Chen, Mike; Chen, Zhiwei; Cho, Jungyeon; Choi, Minho; Choi, Youngwoo; Choi, Yunhee; Chrysostomou, Antonio; Chung, Eun Jung; Dai, Sophia; Debattista, Victor; Di Francesco, James; Diep, Pham Ngoc; Doi, Yasuo; Duan, Hao-Yuan; Duan, Yan; Eswaraiah, Chakali; Fanciullo, Lapo; Fiege, Jason; Fissel, Laura M.; Franzmann, Erica; Friberg, Per; Friesen, Rachel; Fuller, Gary; Furuya, Ray; Gledhill, Tim; Graves, Sarah; Greaves, Jane; Griffin, Matt; Gu, Qilao; Han, Ilseung; Hayashi, Saeko; Hoang, Thiem; Houde, Martin; Hull, Charles L. H.; Inoue, Tsuyoshi; Inutsuka, Shu-ichiro; Iwasaki, Kazunari; Jeong, Il-Gyo; Johnstone, Doug; Koenyves, Vera; Kang, Ji-hyun; Kang, Miju; Kataoka, Akimasa; Kawabata, Koji; Kemper, Francisca; Kim, Jongsoo; Kim, Shinyoung; Kim, Gwanjeong; Kim, Kyoung Hee; Kim, Mi-Ryang; Kim, Kee-Tae; Kim, Hyosung; Kirchschlager, Florian; Kobayashi, Masato I. N.; Koch, Patrick M.; Kusune, Takayoshi; Kwon, Jungmi; Lacaille, Kevin; Law, Chi-Yan; Lee, Chang Won; Lee, Hyeseung; Lee, Yong-Hee; Lee, Chin-Fei; Lee, Jeong-Eun; Lee, Sang-Sung; Li, Dalei; Li, Di; Li, Guangxing; Li, Hua-bai; Lin, Sheng-Jun; Liu, Hong-Li; Liu, Tie; Liu, Sheng-Yuan; Liu, Junhao; Longmore, Steven; Lu, Xing; Lyo, A-Ran; Mairs, Steve; Matsumura, Masafumi; Matthews, Brenda; Moriarty-Schieven, Gerald; Nagata, Tetsuya; Nakamura, Fumitaka; Nakanishi, Hiroyuki; Ngoc, Nguyen Bich; Ohashi, Nagayoshi; Onaka, Takashi; Park, Geumsook; Parsons, Harriet; Peretto, Nicolas; Priestley, Felix; Pyo, Tae-Soo; Qian, Lei; Rao, Ramprasad; Rawlings, Jonathan; Rawlings, Mark; Retter, Brendan; Richer, John; Rigby, Andrew; Sadavoy, Sarah; Saito, Hiro; Savini, Giorgio; Seta, Masumichi; Shimajiri, Yoshito; Shinnaga, Hiroko; Tahani, Mehrnoosh; Tamura, Motohide; Tang, Ya-Wen; Tang, Xindi; Tomisaka, Kohji; Tram, Le Ngoc; Tsukamoto, Yusuke; Viti, Serena; Wang, Hongchi; Wu, Jintai; Xie, Jinjin; Yang, Meng-Zhe; Yen, Hsi-Wei; Yoo, Hyunju; Yuan, Jinghua; Yun, Hyeong-Sik; Zenko, Tetsuya; Zhang, Guoyin; Zhang, Yapeng; Zhang, Chuan-Peng; Zhou, Jianjun; Zhu, Lei; de Looze, Ilse; Andre, Philippe; Dowell, C. Darren; Eden, David; Eyres, Stewart; Falle, Sam; Le Gouellec, Valentin J. M.; Poidevin, Frederick; Robitaille, Jean-Francois; van Loo, Sven Univ Cent Lancashire, Jeremiah Horrocks Inst, Preston PR1 2HE, Lancs, England; UCL, Dept Phys & Astron, London WC1E 6BT, England; Cardiff Univ, Sch Phys & Astron, Cardiff CF24 3AA, Wales; East Asian Observ, 660 N Aohoku Pl,Univ Pk, Hilo, HI 96720 USA; Univ Montreal, Ctr Rech Astrophys Quebec, CP 6128 Succ Ctr Ville, Montreal, PQ H3C 3J7, Canada; Univ Montreal, Dept Phys, CP 6128 Succ Ctr Ville, Montreal, PQ H3C 3J7, Canada; Zhejiang Lab, Kechuang Ave, Hangzhou 311121, Peoples R China; Worcester State Univ, Dept Earth Environm & Phys, Worcester, MA 01602 USA; Harvard Smithsonian Ctr Astrophys, 60 Garden St, Cambridge, MA 02138 USA; Korea Astron & Space Sci Inst, 776 Daedeokdae Ro, Daejeon 34055, South Korea; Univ Sci & Technol, 217 Gajeong Ro, Daejeon 34113, South Korea; Seoul Natl Univ, Dept Earth Sci Educ, 1 Gwanak Ro, Seoul 08826, South Korea; Seoul Natl Univ, SNU Astron Res Ctr, 1 Gwanak Ro, Seoul 08826, South Korea; Indian Inst Astrophys, 2 Block, Bengaluru 560034, India; Acad Sinica, Inst Astron & Astrophys, Sec 4,Roosevelt Rd, Taipei 10617, Taiwan; Natl Astron Observ Japan, Natl Inst Nat Sci, Mitaka, Tokyo 1818588, Japan; Natl Tsing Hua Univ, Inst Astron, Hsinchu 30013, Taiwan; Natl Tsing Hua Univ, Dept Phys, Hsinchu 30013, Taiwan; Nanjing Univ, Sch Astron & Space Sci, 163 Xianlin Ave, Nanjing 210023, Peoples R China; Nanjing Univ, Minist Educ, Key Lab Modern Astron & Astrophys, Nanjing 210023, Peoples R China; Natl Astron Observ Japan, Div Sci, 2-21-1 Osawa, Mitaka, Tokyo 1818588, Japan; SKA Observ, Jodrell Bank, Macclesfield SK11 9FT, Cheshire, England; Univ Manchester, Sch Phys & Astron, Jodrell Bank Ctr Astrophys, Oxford Rd, Manchester, Lancs, England; Natl Cent Univ, Inst Astron, Zhongli 32001, Taiwan; Univ Victoria, Dept Phys & Astron, Victoria, BC V8W 2Y2, Canada; Chinese Acad Sci, Purple Mt Observ, 2 West Beijing Rd, Nanjing 210008, Peoples R China; Chungnam Natl Univ, Dept Astron & Space Sci, Daejeon 34134, South Korea; Seoul Natl Univ, Dept Phys & Astron, Seoul 08826, South Korea; Chinese Acad Sci, Natl Astron Observ, A20 Datun Rd, Beijing 100012, Peoples R China; NRC Herzberg Astron & Astrophys, 5071 West Saanich Rd, Victoria, BC V9E 2E7, Canada; Vietnam Acad Sci & Technol, Vietnam Natl Space Ctr, Hanoi, Vietnam; Univ Tokyo, Grad Sch Arts & Sci, Dept Earth Sci & Astron, 3-8-1 Komaba, Tokyo 1538902, Japan; Indian Inst Sci Educ & Res IISER Tirupati, Karakambadi Rd,Mangalam PO, Tirupati 517507, Andhra Pradesh, India; Natl Chung Hsing Univ, 145 Xingda Rd, Taichung 402, Taiwan; Univ Manitoba, Dept Phys & Astron, Winnipeg, MB R3T 2N2, Canada; Queens Univ, Dept Phys Engn Phys & Astrophys, Kingston, ON K7L 3N6, Canada; Natl Radio Astron Observ, 520 Edgemont Rd, Charlottesville, VA 22903 USA; Tokushima Univ, Inst Liberal Arts & Sci, Minami Jousanajima Machi 1-1, Tokushima 7708502, Japan; Univ Hertfordshire, Sch Phys Astron & Math, Coll Lane, Hatfield AL10 9AB, Herts, England; Chinese Acad Sci, Shanghai Astro Observ, 80 Nandan Rd, Shanghai 200030, Peoples R China; Natl Astron Observ Japan, Subaru Telescope, 650 N Aohoku Pl, Hilo, HI 96720 USA; Univ Western Ontario, Dept Phys & Astron, 1151 Richmond St, London, ON N6A 3K7, Canada; Natl Astron Observ Japan, Alonso de Cordova 3788,Off 61B, Santiago, Chile; Joint ALMA Observ, Alonso de Cordova 3107, Santiago, Chile; Konan Univ, Dept Phys, Higashinada Ku, Okamoto 8-9-1, Kobe, Hyogo 6588501, Japan; Nagoya Univ, Grad Sch Sci, Dept Phys, Chikusa Ku, Nagoya, Aichi 4648602, Japan; Doshisha Univ, Dept Environm Syst Sci, Miyakodani 1-3, Kyoto 6100394, Japan; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu, South Korea; Natl Astron Observ Japan, Div Theoret Astron, Mitaka, Tokyo 1818588, Japan; Hiroshima Univ, Hiroshima Astrophys Sci Ctr, Kagamiyama I-3-1, Hiroshima 7398526, Japan; Hiroshima Univ, Dept Phys, Kagamiyama 1-3-1, Hiroshima 7398526, Japan; Hiroshima Univ, Core Res Energet Universe, Kagamiyama 1-3-1, Hiroshima 7398526, Japan; CSIC, Inst Space Sci ICE, Barcelona 08193, Spain; ICREA, Pg Lluis Companys 23, Barcelona, Spain; Inst Estudis Espacials Catalunya IEEC, E-08034 Barcelona, Spain; Natl Astron Observ Japan, Natl Inst Nat Sci, Nobeyama Radio Observ, Minamisa Ku, Minamimaki, Nagano 3841305, Japan; Kyung Hee Univ, Sch Space Res, 1732 Deogyeong Daero, Yongin 17104, Gyeonggi Do, South Korea; Univ Ghent, Sterrenkundig Observatorium, Krijgslaan 281-S9, B-9000 Ghent, Belgium; Tohoku Univ, Astron Inst, Grad Sch Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan; Univ Tokyo, Grad Sch Sci, Dept Astron, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan; McMaster Univ, Dept Phys & Astron, Hamilton, ON L8S 4M1, Canada; Dalhousie Univ, Dept Phys & Atmospher Sci, Halifax, NS B3H 4R2, Canada; Chinese Univ Hong Kong, Dept Phys, Shatin, Hong Kong, Peoples R China; Chalmers Univ Technol, Dept Space Earth & Environm, SE-41296 Gothenburg, Sweden; Kyung Hee Univ, Sch Space Res, Gyeonggi Do 17104, South Korea; Chinese Acad Sci, Xinjiang Astron Observ, Xinjiang 830011, Urumqi, Peoples R China; Chinese Acad Sci, CAS Key Lab FAST, Natl Astron Observ, Beijing, Peoples R China; Yunnan Univ, Dept Astron, Kunming 650091, Yunnan, Peoples R China; Chinese Acad Sci, Key Lab Res Galaxies & Cosmol, Shanghai Astron Observ, 80 Nandan Rd, Shanghai 200030, Peoples R China; Liverpool John Moores Univ, Astrophys Res Inst, 146 Brownlow Hill, Liverpool L3 5RF, Merseyside, England; Kagawa Univ, Fac Educ, Saiwai Cho 1-1, Takamatsu, Kagawa 7608522, Japan; Kagawa Univ, Ctr Educ Dev & Support, Saiwai Cho 1-1, Takamatsu, Kagawa 7608522, Japan; Kyoto Univ, Grad Sch Sci, Dept Astron, Sakyo Ku, Kyoto 6068502, Japan; SOKENDAI Grad Univ Adv Studies, Hayama, Kanagawa 2400193, Japan; Kagoshima Univ, Grad Sch Sci & Engn, Dept Phys & Astron, 1-21-35 Korimoto, Kagoshima 8900065, Japan; Vietnam Acad Sci & Technol, Grad Univ Sci & Technol, Hanoi, Vietnam; Meisei Univ, Dept Phys, Fac Sci & Engn, 2-1-1 Hodokubo, Hino, Tokyo 1918506, Japan; Univ Tokyo, Grad Sch Sci, Dept Astron, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan; Gemini Observ, NSFs NOIRLab, 670 N Aohoku Pl, Hilo, HI 96720 USA; Cavendish Lab, Astrophys Grp, JJ Thomson Ave, Cambridge CB3 0HE, England; Univ Cambridge, Kavli Inst Cosmol, Inst Astron, Madingley Rd, Cambridge CB3 0HA, England; Univ Tsukuba, Fac Pure & Appl Sci, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058577, Japan; UCL, Phys & Astron Dept, OSL, London WC1E 6BT, England; Kwansei Gakuin Univ, Sch Sci & Technol, Dept Phys, 2-1 Gakuen, Sanda, Hyogo 6691337, Japan; Kyushu Kyoritsu Univ, Yahatanishi Ku, 1-8 Jiyugaoka, Kitakyushu, Fukuoka 8078585, Japan; Natl Res Council Canada, Herzberg Astron & Astrophys Res Ctr, Dominion Radio Astrophys Observ, POB 248, Penticton, BC V2A 6J9, Canada; Natl Inst Nat Sci, Astrobiol Ctr, 2-21-1 Osawa, Mitaka, Tokyo 1818588, Japan; Chinese Acad Sci, Xinjiang Astron Observ, Urumqi 830011, Peoples R China; Univ Sci & Technol Hanoi, Vietnam Acad Sci & Technol, Hanoi, Vietnam; UCL, Phys & Astron Dept, London WC1E 6BT, England; Korea Astron & Space Sci Inst, Daejeon 34055, South Korea; Beijing Normal Univ, Dept Astron, Beijing 100875, Peoples R China; Univ Paris Saclay, Univ Paris Cite, CNRS, Lab Astrophys AIM,CEA, F-91191 Gif Sur Yvette, France; Jet Prop Lab, M-S 169-506,4800 Oak Grove Dr, Pasadena, CA 91109 USA; Armagh Observ & Planetarium, Armagh BT61 9DG, North Ireland; Univ South Wales, Pontypridd CF37 1DL, M Glam, Wales; Univ Leeds, Dept Appl Math, Woodhouse Lane, Leeds LS2 9JT, W Yorkshire, England; Univ Space Res Assoc, SOFIA Sci Ctr, NASA Ames Res Ctr, Moffett Field, CA 94035 USA; Inst Astrofis Canarias, E-38200 Tenerife, Canary Islands, Spain; Univ La Laguna ULL, Dept Astrofis, E-38206 Tenerife, Spain; Univ Grenoble Alpes, CNRS, IPAG, F-38000 Grenoble, France; Univ Leeds, Sch Phys & Astron, Woodhouse Lane, Leeds LS2 9JT, W Yorkshire, England ONAKA, TAKASHI/G-5058-2014; NGOC, NGUYEN/JQJ-4239-2023; Li, Dalei/ABF-2406-2021; Koch, Patrick/AAV-3373-2021; Kemper, Francisca/AAZ-8274-2020; Doi, Yasuo/A-3395-2013; Lee, Sang-Sung/AFS-2722-2022; Lee, Chin-Fei/AAZ-3391-2020; Arzoumanian, Doris/JQT-3284-2023; , Le Ngoc Tram/AAH-2951-2019; Li, Di/HLH-4146-2023; Savini, Giorgio/F-5753-2019; 顏士韋, Hsi-Wei/C-8307-2011; Nanayakkara, Themiya/AAT-6271-2020; Ohashi, Nagayoshi/ABA-9767-2020; Tang湯雅雯, Ya-Wen/AAZ-7382-2020; Gu, Qilao/LTZ-1282-2024; Li, Xuming/JLM-6754-2023; Savini, Gianluca/C-1188-2009; Inutsuka, Shu-ichiro/I-7024-2014; Liu, Junhao/AAQ-3071-2021; Kim, Shinyoung/JEO-8879-2023; Han, Ilseung/MBG-4273-2025; WANG, Qiuhong/L-9577-2016; Chen, Zhiwei/HJH-4481-2023; Soam, Archana/AAG-4250-2021; Tsukamoto, Yusuke/AAU-3453-2020; LI, DI/HLH-4146-2023; Rao, Ramprasad/L-2115-2017; Kataoka, Akimasa/AAU-5038-2020; Lee, Jeong-Eun/E-2387-2013; Hwang, Jihye/JXW-6363-2024; Priestley, Felix/KYP-3257-2024; Li, Hua-bai/AEU-0239-2022; Yuan, Jinghua/W-4699-2017; Liu, Hong-Li/AAR-1998-2020; Poidevin, Frédérick/Z-3492-2019; Tomisaka, Kohji/E-6508-2013; Van Loo, Sven/JRX-9178-2023; Li, Guang-Xing/AAC-9285-2022; Shimajiri, Yoshito/B-1445-2013; Liu, Sheng-Yuan/AAZ-4303-2020; Chakali, Eswaraiah/L-5146-2018; Lee, Chang/HME-1129-2023 DWard-Thompson@uclan.ac.uk; ASTROPHYSICAL JOURNAL ASTROPHYS J 0004-637X 1538-4357 946 2 SCIE ASTRONOMY & ASTROPHYSICS 2023 4.8 17.3 6 AMMONIA SPECTRAL MAP; DENSE CORES; L1495-B218 FILAMENTS; FORMING REGION; MU-M; HERSCHEL; SCUBA-2; JCMT; POLARIZATION; VIEW English 2023 2023-04-01 10.3847/1538-4357/acbea4 바로가기 바로가기 바로가기
Article Metformin increases the expression of proinflammatory cytokines and inhibits supraspinatus fatty infiltration Background After a rotator cuff (RC) tendon tear, the supraspinatus (SS) inflammatory response induces fatty infiltration (FI). Metformin has the effect of regulating the initial inflammatory response of atrophic muscles. Therefore, this study aimed to investigate the effect of metformin use on modulating the expression of proinflammatory cytokines and SS FI in an acute RC tear rat model. Methods This study used 26 male Sprague-Dawley rats. Animals were randomly divided into two groups: The metformin group received metformin for 5 days after cutting the RC tendon, and the control group was administered only with saline after cutting the tendon. Metformin 50 mg/kg was intraperitoneally injected for 5 days. Three rats in each group were sacrificed 5 days after SS tendon rupture surgery, and 10 rats in each group were sacrificed 14 days after surgery. The SS was sampled 5 days after SS tendon tear surgery, and the expression of proinflammatory cytokines was measured by quantitative reverse-transcription polymerase chain reaction (qRT-PCR). On day 14 after sampling, histological analysis of the SS was performed using hematoxylin and eosin, Masson's trichrome, and picrosirius red staining. Results On day 5 of surgery, the expression values of interferon gamma (increased 7.2-fold, P <.01), tumor necrosis factor alpha (increased 13-fold, P <.05), interleukin-1 beta (increased 4.7-fold, P <.001), and interleukin-6 (increased 4.6-fold, P <.01) increased significantly in the metformin group compared with those in the control group. As a result of Oil Red O staining, SS FI was significantly suppressed in the metformin group compared with that in the control group (metformin group, 305 +/- 50.3 mu m(2), P <.001; control group, 3136 +/- 662.8 mu m(2), P <.001). In addition, the SS volume of the metformin group was not reduced compared with those of the control group, and the morphology and structure of the SS were better preserved. Conclusions The results of this study revealed that metformin can increase the expression of proinflammatory cytokines and suppress SS fat infiltration in delayed sutures. Yoon, Jong Pil; Park, Sung-Jin; Kim, Dong-Hyun; Chung, Seok Won Kyungpook Natl Univ, Sch Med, Dept Orthopaed Surg, Daegu, South Korea; KonKuk Univ, Med Ctr, Dept Orthopaed Surg, Sch Med, Seoul, South Korea 36098548400; 58527890700; 57198637188; 37065938600 knuhos_sh2@naver.com; JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH J ORTHOP SURG RES 1749-799X 18 1 SCIE ORTHOPEDICS 2023 2.8 17.3 1.45 2025-06-25 5 5 Metformin; Inflammatory response; Fatty infiltration; Supraspinatus atrophy; Histology; Rotator cuff tear ROTATOR CUFF REPAIR; DEGENERATION; CELLS; TEARS; ATROPHY; RISK; NEER Fatty infiltration; Histology; Inflammatory response; Metformin; Rotator cuff tear; Supraspinatus atrophy Animals; Cytokines; Male; Metformin; Rats; Rats, Sprague-Dawley; Rotator Cuff; Rotator Cuff Injuries; Tendons; cytokine; metformin; animal; male; rat; rotator cuff; rotator cuff injury; Sprague Dawley rat; tendon English 2023 2023-09-12 10.1186/s13018-023-04163-z 바로가기 바로가기 바로가기 바로가기
Article Performance of Cardiovascular Risk Prediction Models in Korean Patients With New-Onset Rheumatoid Arthritis: National Cohort Study BackgroundThis study aimed to compare the performance of established cardiovascular risk algorithms in Korean patients with new-onset rheumatoid arthritis.Methods and ResultsThis retrospective cohort study identified patients newly diagnosed with rheumatoid arthritis without a history of cardiovascular diseases between 2013 and 2019 using the National Health Insurance Service database. The cohort was followed up until 2020 for the development of the first major adverse cardiovascular event. General cardiovascular risk prediction algorithms, such as the systematic coronary risk evaluation model, the Korean risk prediction model for atherosclerotic cardiovascular diseases, the American College of Cardiology/American Heart Association pooled equations, and the Framingham Risk Score, were used. The discrimination and calibration of cardiovascular risk prediction models were evaluated. Hazard ratios were estimated using Cox proportional hazards regression. A total of 611 patients among 24 889 patients experienced a major adverse cardiovascular event during follow-up. The median 10-year atherosclerotic cardiovascular diseases risk score was significantly higher in patients with major adverse cardiovascular events than those without. The C-statistics of risk algorithms ranged between 0.72 and 0.74. Compared with the low-risk group, the actual risk of developing major adverse cardiovascular events increased significantly in the intermediate- and high-risk groups for all algorithms. However, the risk predictions calculated from all algorithms overestimated the observed cardiovascular risk in the middle to high deciles, and only the systematic coronary risk evaluation algorithm showed comparable observed and predicted event rates in the low-intermediate deciles with the highest sensitivity.ConclusionsThe systematic coronary risk evaluation model algorithm and the general risk prediction models discriminated patients with rheumatoid arthritis appropriately. However, overestimation should be considered when applying the cardiovascular risk prediction model in Korean patients. Kim, Jae Hyun; Lee, Gaeun; Hwang, Jinseub; Kim, Ji-Won; Kwon, Jin-Won; Song, Yun-Kyoung Jeonbuk Natl Univ, Sch Pharm, Jeonju, South Korea; Jeonbuk Natl Univ, Inst New Drug Dev, Jeonju, South Korea; Daegu Univ, Dept Stat, Gyeongbuk, South Korea; Daegu Catholic Univ, Dept Internal Med, Div Rheumatol, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Coll Pharm, FOUR Community Based Intelligent Novel Drug Discov, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu, South Korea; Daegu Catholic Univ, Coll Pharm, 13-13 Hayang Ro, Gyongsan 38430, Gyeongbuk, South Korea Bin Kim, Hong/J-5452-2012; Kim, Ju-Hyoung/N-1450-2019 57193420203; 58692232500; 57189231296; 57251295000; 16202951700; 56136407200 yksong@cu.ac.kr; JOURNAL OF THE AMERICAN HEART ASSOCIATION J AM HEART ASSOC 2047-9980 12 22 SCIE CARDIAC & CARDIOVASCULAR SYSTEMS 2023 5 17.3 0.19 2025-06-25 0 1 cardiovascular risk prediction; Korean; major adverse cardiovascular events; rheumatoid arthritis CORONARY-ARTERY; DISEASE; SCORE; VALIDATION; PREVENTION; EVENTS; CARE cardiovascular risk prediction; Korean; major adverse cardiovascular events; rheumatoid arthritis Adult; Aged; Algorithms; Arthritis, Rheumatoid; Cardiovascular Diseases; Databases, Factual; Female; Heart Disease Risk Factors; Humans; Male; Middle Aged; Prognosis; Republic of Korea; Retrospective Studies; Risk Assessment; Risk Factors; adult; aged; Article; calibration; cardiovascular disease; cardiovascular risk; cohort analysis; controlled study; coronary atherosclerosis; disease risk assessment; female; follow up; Framingham risk score; human; Korean (people); major clinical study; male; medical society; national health insurance; prediction; retrospective study; rheumatoid arthritis; risk algorithm; algorithm; cardiovascular disease; complication; diagnosis; epidemiology; factual database; heart disease risk factor; middle aged; procedures; prognosis; risk assessment; risk factor; South Korea English 2023 2023-11-21 10.1161/jaha.123.030604 바로가기 바로가기 바로가기 바로가기
Article RadioAstron Space VLBI Imaging of the Jet in M87. I. Detection of High Brightness Temperature at 22 GHz We present results from the first 22 GHz space very long baseline interferometric (VLBI) imaging observations of M87 by RadioAstron. As a part of the Nearby AGN Key Science Program, the source was observed in 2014 February at 22 GHz with 21 ground stations, reaching projected (u, v) spacings up to similar to 11 G.. The imaging experiment was complemented by snapshot RadioAstron data of M87 obtained during 2013-2016 from the AGN Survey Key Science Program. Their longest baselines extend up to similar to 25 G.. For all of these measurements, fringes are detected only up to similar to 2.8 Earth diameter or similar to 3G. baseline lengths, resulting in a new image with angular resolution of similar to 150 mu as or similar to 20 Schwarzschild radii spatial resolution. The new image not only shows edgebrightened jet and counterjet structures down to submilliarcsecond scales but also clearly resolves the VLBI core region. While the overall size of the core is comparable to those reported in the literature, the ground-space fringe detection and slightly superresolved RadioAstron image suggest the presence of substructures in the nucleus, whose minimum brightness temperature exceeds TB, min 10 similar to 12 K. It is challenging to explain the origin of this record-high TB, min value for M87 by pure Doppler boosting effect with a simple conical jet geometry and known jet speed. Therefore, this can be evidence for more extreme Doppler boosting due to a blazar-like small jet viewing angle or highly efficient particle acceleration processes occurring already at the base of the outflow. Kim, Jae-Young; Savolainen, Tuomas; Voitsik, Petr; Kravchenko, Evgeniya V. V.; Lisakov, Mikhail M. M.; Kovalev, Yuri Y. Y.; Mueller, Hendrik; Lobanov, Andrei P. P.; Sokolovsky, Kirill V. V.; Bruni, Gabriele; Edwards, Philip G. G.; Reynolds, Cormac; Bach, Uwe; Gurvits, Leonid I. I.; Krichbaum, Thomas P. P.; Hada, Kazuhiro; Giroletti, Marcello; Orienti, Monica; Anderson, James M.; Lee, Sang-Sung; Sohn, Bong Won; Zensus, J. Anton Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 702701, South Korea; Max Planck Inst Radioastron, Hugel 69, D-53121 Bonn, Germany; Aalto Univ, Dept Elect & Nanoengn, PL 15500, FI-00076 Aalto, Finland; Aalto Univ, Metsahovi Radio Observ, Metsahovintie 114, FI-02540 Kylmala, Finland; Russian Acad Sci, Lebedev Phys Inst, Leninsky Prospekt 53, Moscow 119991, Russia; Moscow Inst Phys & Technol, Inst Per 9, Moscow 141700, Russia; Univ Illinois, Dept Astron, 1002 W Green St, Urbana, IL 61801 USA; Michigan State Univ, Ctr Data Intens & Time Domain Astron, Dept Phys & Astron, 567 Wilson Rd, E Lansing, MI 48824 USA; Moscow MV Lomonosov State Univ, Sternberg Astron Inst, Univ Skij Pr 13, Moscow 119992, Russia; Ist Astrofis & Planetol Spaziali, INAF, Via Fosso Cavaliere 100, I-00133 Rome, Italy; CSIRO Astron & Space Sci, POB 76, Epping, NSW 1710, Australia; CSIRO Astron & Space Sci, POB 1130, Bentley, WA 6102, Australia; Joint Inst VLBI ERIC JIVE, Oude Hoogeveensedijk 4, NL-7991 PD Dwingeloo, Netherlands; Delft Univ Technol, Fac Aerosp Engn, Kluyverweg 1, NL-2629 HS Delft, Netherlands; Mizusawa VLBI Observ, Natl Astron Observ Japan, 2-12 Hoshigaoka, Oshu, Iwate 0230861, Japan; Grad Univ Adv Studies SOKENDAI, Dept Astron Sci, 2-21-1 Osawa,Mitaka Ku, Tokyo 1818588, Japan; Ist Nazl Astrofis, Ist Radioastron IRA, Via Gobetti 101, I-40129 Bologna, Italy; Leibniz Inst Agr Engn & Bioecon, Max Eyth Allee 100, D-14469 Potsdam, Germany; Korea Astron & Space Sci Inst, 776 Daedeok Daero, Daejeon 34055, South Korea ; Lee, Sang-Sung/AFS-2722-2022; Kim, Jae-Young/IUO-6466-2023; Kravchenko, Evgeniya/M-7464-2013; Mueller, Hendrik/JXL-4021-2024; Edwards, Philip/AAV-5623-2021; Lisakov, Mikhail/M-6034-2013; Bruni, Gabriele/ABB-2523-2021; Reynolds, Cormac/AFS-0191-2022; Lisakov, Mikhail/JAX-3277-2023; Kovalev, Yuri/J-5671-2013; Sokolovsky, Kirill/D-2246-2015; Voitsik, Petr/M-6075-2013; Bach, Udo/F-3880-2012 57211836467; 7003371610; 24400306800; 56022673900; 25958231300; 7004589011; 57219733023; 7101957568; 25644982200; 56950092500; 7401881919; 7402331605; 8356678200; 7006254892; 7004015011; 45361061000; 53982857600; 6507925285; 55731058800; 37056945900; 25628978700; 7004929291 jykim@knu.ac.kr; ASTROPHYSICAL JOURNAL ASTROPHYS J 0004-637X 1538-4357 952 1 SCIE ASTRONOMY & ASTROPHYSICS 2023 4.8 17.3 1.19 2025-06-25 11 10 ACTIVE GALACTIC NUCLEI; PARSEC-SCALE JETS; GAMMA-RAY EMISSION; AGN JETS; INNERMOST REGIONS; MAGNETIC-FIELDS; RELATIVISTIC JETS; DOPPLER FACTORS; RADIO-SOURCES; BL LACERTAE English 2023 2023-07-01 10.3847/1538-4357/accf17 바로가기 바로가기 바로가기 바로가기
Article Serum Acylcarnitine and Long-Term Functional Prognosis after Traumatic Brain Injury with Intracranial Injury: A Multi-Center Prospective Study Serum biomarkers have potential to help predict prognosis of traumatic brain injury (TBI). The objective of this study was to evaluate the association between serum acylcarnitine levels and functional outcomes at 1 month/6 months after injury for TBI patients with intracranial hemorrhage or diffuse axonal injury. This study is a multi-center prospective cohort study in which adult TBI patients with intracranial injury visiting the emergency departments (EDs) from December 2018 to June 2020 were enrolled. Serum acylcarnitine levels at the time of ED arrival were categorized into four groups: low (1.2-5.5 mu mol/L), low-normal (5.6-10.0 mu mol/L), high-normal (10.1-14.5 mu mol/L), and high (1.4.6-56.6 mu mol/L). The study outcome was set as poor functional recovery at 1 month/6 months after injury (Glasgow Outcome Scale score, 1-3). Multi-level logistic regression analyses were conducted to estimate association between serum acylcarnitine and functional outcomes. Among total of 549 patients, poor functional recovery at 1 month and 6 months after injury were observed in 29.1% (160/549) and 29.1% (158/543, follow-up loss n = 6). The odds for 1-month poor functional outcome increased in the high-normal and the high groups [adjusted odds ratios, AORs (95% confidence intervals, CIs): 1.56 (1.09-2.23) and 2.47 (1.63-3.75)], compared with the low-normal group) and also as a continuous variable [1.05 (1.03-1.07) for each 1 mu mol/L]. Regarding 6-month mortality, the high group had significantly higher odds when compared with the low-normal group [AOR (95% CI): 2.16 (1.37-3.40)]. Higher serum acylcarnitine levels are associated with poor functional outcomes at 1 month/6 months after injury for TBI patients with intracranial injury. Lee, Stephen Gyung Won; Ro, Young Sun; Jung, Eujene; Moon, Sung Bae; Park, Gwan Jin; Yoon, Hanna; Park, Jeong Ho; Shin, Sang Do Seoul Natl Univ, Dept Emergency Med, Boramae Med Ctr, Seoul, South Korea; Seoul Natl Univ Hosp, Lab Emergency Med Serv, Biomed Res Inst, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Emergency Med, 101 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Dept Emergency Med, Coll Med, Seoul, South Korea; Chonnam Natl Univ Hosp, Dept Emergency Med, Gwangju, South Korea; Kyungpook Natl Univ, Dept Emergency Med, Sch Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Daegu, South Korea; Chungbuk Natl Univ Hosp, Dept Emergency Med, Cheongju, South Korea Do Shin, Sang/D-6020-2012 57221045307; 37665990400; 57194543281; 57191584601; 57193389046; 57218530108; 57222635486; 57049712400 ro.youngsun@gmail.com; JOURNAL OF NEUROTRAUMA J NEUROTRAUM 0897-7151 1557-9042 40 3-4 SCIE CLINICAL NEUROLOGY;CRITICAL CARE MEDICINE;NEUROSCIENCES 2023 3.9 17.3 0.76 2025-06-25 5 5 acylcarnitine; prognosis; traumatic brain injury CARNITINE; BIOMARKERS; IMPROVE; S100B acylcarnitine; prognosis; traumatic brain injury Adult; Brain Injuries; Brain Injuries, Traumatic; Glasgow Coma Scale; Humans; Prognosis; Prospective Studies; acylcarnitine; acylcarnitine; adult; aged; Article; body mass; brain function; brain injury; cohort analysis; computer assisted tomography; consciousness; controlled study; emergency ward; female; Glasgow outcome scale; human; injury scale; liquid chromatography-mass spectrometry; logistic regression analysis; long term care; major clinical study; male; multicenter study; nuclear magnetic resonance imaging; outcome assessment; prognosis; prospective study; Rankin scale; sensitivity analysis; traumatic brain injury; clinical trial; complication; Glasgow coma scale; prognosis; traumatic brain injury English 2023 2023-02-01 10.1089/neu.2022.0096 바로가기 바로가기 바로가기 바로가기
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