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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Bright and fast scintillations of an inorganic halide perovskite CsPbBr3 crystal at cryogenic temperatures Highly efficient scintillation crystals with short decay times are indispensable for improving the performance of numerous detection and imaging instruments that use- X-rays, gamma-quanta, ionising particles or neutrons. Halide perovskites emerged recently as very promising materials for detection of ionising radiation that motivated further exploration of the materials. In this work, we report on excellent scintillation properties of CsPbBr3 crystals when cooled to cryogenic temperatures. The temperature dependence of luminescence spectra, decay kinetics and light yield under excitation with X-rays and alpha-particles was investigated. It is shown that the observed changes of spectral and kinetic characteristics of the crystal with temperature can be consistently explained by radiative decay of free excitons, bound and trapped excitons as well as electron-hole pairs originating from their disintegration. It has been found that the crystal exhibits a fast decay time constant of 1 ns at 7 K. The scintillation light yield of CsPbBr3 at 7 K is assessed to be 50,000 +/- 10,000 ph/MeV at excitation with 12 keV X-rays and 109,000 +/- 22,000 ph/MeV at excitation with alpha-particles of Am-241. This finding places CsPbBr3 in an excellent position for the development of a new generation of cryogenic, efficient scintillation detectors with nanosecond response time, marking a step-change in opportunities for scintillator-based applications. Mykhaylyk, V. B.; Kraus, H.; Kapustianyk, V.; Kim, H. J.; Mercere, P.; Rudko, M.; Da Silva, P.; Antonyak, O.; Dendebera, M. Diamond Light Source, Harwell Campus, Didcot OX11 0DE, Oxon, England; Univ Oxford, Dept Phys, Denys Wilkinson Bldg,Keble Rd, Oxford OX1 3RH, England; I Franko Natl Univ Lviv, Sci Tech & Educ Ctr Low Temp Studies, 50 Dragomanova Str, UA-79005 Lvov, Ukraine; Kyungpook Natl Univ, Dept Phys, 1370 Sangyeok Dong, Taegu 702701, South Korea; LOrme Merisiers, Synchrotron Soleil, BP 48, F-91192 Gif Sur Yvette, France; I Franko Natl Univ Lviv, Dept Phys, 8 Kyrylo & Mefodiy Str, UA-79005 Lvov, Ukraine Mikhailik, Vitaliy/L-5389-2016; Kraus, Hans/B-7833-2016; Rudko, Michael/L-3106-2018 54420706100; 9235797700; 14421180200; 59051568100; 6602278793; 56568085400; 57198154194; 6602357798; 57216740773 vitaliy.mykhaylyk@diamond.ac.uk; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 2.04 2025-06-25 74 70 CDSE QUANTUM DOTS; X-RAY; SINGLE-CRYSTALS; PHOTOLUMINESCENCE; EXCITON; NANOCRYSTALS; DEPENDENCE; EMISSION; LUMINESCENCE; DYNAMICS English 2020 2020-05-25 10.1038/s41598-020-65672-z 바로가기 바로가기 바로가기 바로가기
Article Citizen science via social media revealed conditions of symbiosis between a marine gastropod and an epibiotic alga Environmental factors promote symbiosis, but its mechanism is not yet well understood. The alga Pseudocladophora conchopheria grows only on the shell of an intertidal gastropod Lunella correensis, and these species have a close symbiotic relationship which the alga reduces heat stress of the gastropod. In collaboration with general public, we investigated how environmental conditions alter the symbiotic interaction between the alga and the gastropod. Information about the habitats of each gastropod and images of shells was obtained from the Japanese and Korean coasts via social media. We constructed the hierarchical Bayesian model using the data. The results indicated that the proportion of shell area covered by P. conchopheria increased as the substrate size utilized by the gastropod increased. Meanwhile, temperature did not affect the proportion of P. conchopheria on the shell. These suggested that the alga provides no benefits for the gastropod on small substrates because gastropod can reduce the heat stress by diving into the small sediment. Further, the gastropod’s cost incurred by growing the alga on the shell seems to be low as the algae can grow even in cooler places where no benefits of heat resistance for gastropods. Different environments can yield variable conditions in symbiosis. © 2020, The Author(s). Kagawa, Osamu; Uchida, Shota; Yamazaki, Daishi; Osawa, Yumiko; Ito, Shun; Chiba, Satoshi; Kagawa, Emiko; Tamada, Akihiro; Ishida, So; Yoshida, Junko; Kimura, Kazuki; Iijima, Akiko; Suenaga, Takayuki; Momoi, Teruaki; Kato, You; Nikaido, Satoshi; Kimura, Taeko; Kobayashi, Shingo; Niwa, Kazuo; Nishi, Hirotaka; Fujita, Haruto; Kakihara, Hideaki; Makino, Shinichi; Suzuki, Hiroe; Namikawa, Akane; Yamakami, Ryusei; Higashi, Kanae; Watanabe, Kota; Yoshimura, Taro; Isotomo; Sagara, Mitsunori; Aoki, Yuta; Sugimoto, Ryoya Graduate School of Life Sciences, Tohoku University, Miyagi, Japan; Graduate School of Life Sciences, Tohoku University, Miyagi, Japan, Wildlife Management Office Inc., Tokyo, Japan; Center for Northeast Asian Studies, Tohoku University, Miyagi, Japan; Amakusa Marine Biological Laboratory, Kyushu University, Kumamoto, Japan; Graduate School of Life Sciences, Tohoku University, Miyagi, Japan; Graduate School of Life Sciences, Tohoku University, Miyagi, Japan, Center for Northeast Asian Studies, Tohoku University, Miyagi, Japan; Guest House, Toy Bricks and Books in Manazuru, Kanagawa, Japan; Graduate School of Life Sciences, Tohoku University, Miyagi, Japan; Osaka Museum of Natural History, Osaka, Japan; Independent Researcher, Kumamoto, Japan; Department of Biology, Kyungpook National University, Daegu, South Korea; Department of Spanish and Portuguese, Kanda University of International Studies, Chiba, Japan; Graduate School of Life Sciences, Tohoku University, Miyagi, Japan; Independent Researcher, Chiba, Japan; Independent Researcher, Mie, Japan; Independent Researcher, Tokyo, Japan; Department of Life Sciences, Graduate School of Bioresources, Mie University, Mie, Japan; Ehime Prefectural Science Museum, Ehime, Japan; Hori Milk, Ishikawa, Japan; Toyohashi Museum of Natural History, Aichi, Japan; Nagasaki-Hokuyodai High School, Nagasaki, Japan; Chiba City Buried Cultural Property Center, Chiba, Japan; Independent Researcher, Aichi, Japan; Independent Researcher, Tokyo, Japan; Independent Researcher, Tokyo, Japan; Laboratory of Marine Biology, Graduate School of Fisheries Sciences, Hokkaido University, Hokkaido, Japan; Independent Researcher, Hyogo, Japan; Independent Researcher, Fukui, Japan; Faculty of Economics, Keio University, Tokyo, Japan; Independent Researcher, Tokyo, Japan; Himeji City Science Museum, Hyogo, Japan; Independent Researcher, Ehime, Japan; Independent Researcher, Tokyo, Japan 57204973035; 57191839419; 57195408150; 57219051433; 57215668322; 55697248000; 57219896249; 57219893726; 57219894974; 57219895023; 55464858400; 59787958900; 57219895025; 57219892939; 57219894550; 57219893837; 7405704601; 57219893856; 57219892221; 57219892078; 57219896295; 57219891946; 57219895009; 57219895833; 57219893769; 57219893019; 57219894971; 57219895044; 57194774672; 57219893479; 57219896038; 57219896051; 57219893720 ok.osamukagawa@gmail.com; Scientific Reports SCI REP-UK 2045-2322 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.18 2025-06-25 8 Animal Shells; Animals; Bayes Theorem; Chlorophyta; Citizen Science; Ecosystem; Gastropoda; Heat-Shock Response; Social Media; Symbiosis; Temperature; alga; algal cell culture; article; citizen science; diving; gastropod; habitat; heat stress; heat tolerance; nonhuman; seashore; sediment; social media; symbiosis; animal; animal shell; Bayes theorem; ecosystem; gastropod; green alga; heat shock response; physiology; procedures; temperature English Final 2020 10.1038/s41598-020-74946-5 바로가기 바로가기 바로가기
Article Comparative analyses of the V4 and V9 regions of 18S rDNA for the extant eukaryotic community using the Illumina platform Illumina sequencing is a representative tool for understanding the massive diversity of microbial eukaryotes in natural ecosystems. Here, we investigated the eukaryotic community in a pond (salinity of 2-4) on Dokdo (island) in the East Sea, Korea, using Illumina sequencing with primer sets for the V4 and V9 regions of 18S rDNA from 2016 to 2018 for the first time. Totally, 1,413 operational taxonomic units (OTUs) and 915 OTUs were detected using the V9 and V4 primer sets, respectively. Taxonomic analyses of these OTUs revealed that although the V4 primer set failed to describe the extant diversity for some major sub-division groups, the V9 primer set represented their diversity. Moreover, the rare taxa with <1% of total reads were exclusively detected using V9 primer set. Hence, the diversity of the eukaryotic community can vary depending on the choice of primers. The Illumina sequencing data of the V9 region of 18S rDNA may be advantageous for estimating the richness of the eukaryotic community including a rare biosphere, whereas the simultaneous application of two biomarkers may be suitable for understanding the molecular phylogenetic relationships. We strongly recommend both biomarkers be used to assess the diversity and phylogenetic relationship within the eukaryotic community in natural samples. Choi, Jaeho; Park, Jong Soo Kyungpook Natl Univ, Sch Earth Syst Sci, Dept Oceanog, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Dok Do & Ulleung Do Isl, Daegu 41566, South Korea; Kyungpook Natl Univ, Kyungpook Inst Oceanog, Daegu 41566, South Korea ; Park, Jong/AAJ-3576-2020 57216427376; 23486274100 jongsoopark@knu.ac.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 2.13 2025-06-25 86 82 RIBOSOMAL-RNA GENE; N. SP.; DIVERSITY; GENERATION; HETEROLOBOSEA; CLASSIFICATION; PHYTOPLANKTON; SEDIMENTS; PROTIST; LINEAGE Biomarkers; Classification; DNA, Ribosomal; Eukaryota; Genetic Variation; High-Throughput Nucleotide Sequencing; Phylogeny; RNA, Ribosomal, 18S; Salinity; biological marker; ribosome DNA; RNA 18S; classification; eukaryote; genetic variation; genetics; high throughput sequencing; phylogeny; salinity English 2020 2020-04-16 10.1038/s41598-020-63561-z 바로가기 바로가기 바로가기 바로가기
Article Comparison of surgical outcomes of slanted procedure for exotropia with convergence insufficiency according to their response to preoperative monocular occlusion The aim of this prospective study was to compare surgical outcomes of slanted bilateral lateral rectus (LR) recession for intermittent exotropia (IXT) with convergence insufficiency (CI) according to their response to preoperative monocular occlusion. This prospective study included 55 children who underwent slanted bilateral LR recession for IXT with CI. Patients were divided into two groups according to their response to preoperative monocular occlusion for 2hours. The True CI group was defined as having near-distance differences of >= 10 PD before and after occlusion; the Masked CI group as having near-distance differences of 10 PD prior to and after occlusion. Slanted procedure reduced distance and near exodeviations from 32.1 PD and 43.0 PD to 3.5 PD and 4.4 PD, and collapsed near-distance differences from 10.9 PD to 1.0 PD at 3 years postoperatively. Cumulative probabilities of surgical success were 76%, and the mean recurrence was 50 months at 3 years postoperatively; the True CI and Masked CI groups showed cumulative success rates of 89% and 55%, respectively (p=0.0052). Patients in the True CI group demonstrated surgical outcomes superior to those demonstrated by patients in the Masked CI group after slanted bilateral LR recession. Chun, Bo Young; Oh, Jun Ho; Choi, Hyung Jun Kyungpook Natl Univ, Sch Med, Dept Ophthalmol, Daegu, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Sch Med, Daegu, South Korea 25644902100; 57216588714; 57216589446 byjun424@hotmail.com; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.18 2025-06-25 5 7 RECESSION; RESECTION Adolescent; Bandages; Child; Child, Preschool; Depth Perception; Exotropia; Female; Humans; Male; Ocular Motility Disorders; Preoperative Care; Prospective Studies; Treatment Outcome; Vision, Binocular; adolescent; bandage; binocular vision; child; comparative study; complication; depth perception; divergent strabismus; eye movement disorder; female; human; male; pathophysiology; preoperative care; preschool child; prospective study; treatment outcome English 2020 2020-04-29 10.1038/s41598-020-64251-6 바로가기 바로가기 바로가기 바로가기
Article Congenital abnormalities of the retinal vasculature in neurofibromatosis type I The aim of this cross-sectional study was to investigate congenital abnormalities of the retinal vasculature (CARVs) in patients with neurofibromatosis type I (NF-1). Forty-eight patients (96 eyes) with NF-1 diagnosed according to the National Institutes of Health (NIH) criteria and 48 healthy controls were included in this study. Standard fundus photographs were obtained for each subject to evaluate the presence and frequency of CARVs. The sensitivity, specificity, and diagnostic accuracy of different cut-off numbers of CARVs were compared with those of the NIH criteria. Forty-four (91.7%) patients in the NF-1 group demonstrated either supranumeraty optic disc vessels or triple branching of the retinal vasculature, and 22 patients (45.8%) demonstrated both findings. The frequencies of these two CARVs were significantly different between the two groups (p<0.00001). A cut-off value of either one for supranumerary optic disc vessels or triple branching showed the highest accuracy along with sensitivity and specificity of 91.7% and 87.5%. CARVs such as supranumerary optic disc vessels or triple branching were frequently observed in NF-1 patients, and their occurrence was unrelated to the age of patients. Thus, these CARVs could be added as new ophthalmologic manifestions for NF-1 and may potentially enable early diagnosis of NF-1. Chun, Bo Young; Yoon, Jung Hyun; Son, Byeong Jae; Hwang, Su-Kyeong; Lim, Hyun Taek Kyungpook Natl Univ, Sch Med, Dept Ophthalmol, Daegu, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat Neurol, Daegu, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Ophthalmol, Seoul, South Korea Yoon, Jung Hyun/KHX-0113-2024 25644902100; 57204243415; 57197444337; 37761570400; 8441595200 byjun424@hotmail.com; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.18 2025-06-25 4 5 CHOROIDAL ABNORMALITIES; VESSELS; MANAGEMENT; FREQUENCY; FEATURES; DEATH Cross-Sectional Studies; Early Detection of Cancer; Female; Fluorescein Angiography; Humans; Male; Neurofibromatosis 1; Optic Disk; Retinal Vessels; Sensitivity and Specificity; cross-sectional study; diagnostic imaging; early cancer diagnosis; female; fluorescence angiography; human; male; neurofibromatosis type 1; optic disk; pathology; retina blood vessel; sensitivity and specificity; vascularization English 2020 2020-07-30 10.1038/s41598-020-69852-9 바로가기 바로가기 바로가기 바로가기
Article Deep learning enables automated localization of the metastatic lymph node for thyroid cancer on ¹³¹I post-ablation whole-body planar scans The accurate detection of radioactive iodine-avid lymph node (LN) metastasis on I-131 post-ablation whole-body planar scans (RxWBSs) is important in tracking the progression of the metastatic lymph nodes (mLNs) of patients with papillary thyroid cancer (PTC). However, severe noise artifacts and the indiscernible location of the mLN from adjacent tissues with similar gray-scale values make clinical decisions extremely challenging. This study aims (i) to develop a multilayer fully connected deep network (MFDN) for the automatic recognition of mLNs from thyroid remnant tissue by utilizing the dataset of RxWBSs and (ii) to evaluate its diagnostic performance using post-ablation single-photon emission computed tomography. Image patches focused on the mLN and remnant tissues along with their variations of probability of pixel positions were fed as inputs to the network. With this efficient automatic approach, we achieved a high F1-score and outperformed the physician score (P<0.001) in detecting mLNs. Competitive segmentation networks on RxWBS displayed moderate performance for the mLN but remained robust for the remnant tissue. Our results demonstrated that the generalization performance with the multiple layers by replicating signal transmission overcome the constraint of local minimum optimization, it can be suitable to localize the unstable location of mLN region on RxWBS and therefore MFDN can be useful in clinical decision-making to track mLN progression for PTC. Kavitha, MuthuSubash; Lee, Chang-Hee; Shibudas, KattakkaliSubhashdas; Kurita, Takio; Ahn, Byeong-Cheol Hiroshima Univ, Grad Sch Adv Sci & Engn, Hiroshima, Japan; Kyungpook Natl Univ Hosp, Sch Med, Dept Nucl Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea Kavitha, M.S./AAI-6438-2020; Subashda, Shibudas/ABH-2418-2020; Kurita, Takio/D-8674-2012 57218147465; 57148992000; 57216692474; 7201523114; 7202791511 tkurita@hiroshima-u.ac.jp;abc2000@knu.ac.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.5 2025-06-25 17 17 NEURAL-NETWORKS; HEAD; SEGMENTATION; MANAGEMENT; CARCINOMA; TEXTURE Ablation Techniques; Automation; Deep Learning; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Lymphatic Metastasis; Retrospective Studies; Single Photon Emission Computed Tomography Computed Tomography; Thyroid Neoplasms; Whole Body Imaging; Iodine-131; radioactive iodine; ablation therapy; automation; diagnostic imaging; human; image processing; lymph node metastasis; pathology; procedures; retrospective study; single photon emission computed tomography-computed tomography; thyroid tumor; whole body imaging English 2020 2020-05-08 10.1038/s41598-020-64455-w 바로가기 바로가기 바로가기 바로가기
Correction Deep learning enables automated localization of the metastatic lymph node for thyroid cancer on ¹³¹I post-ablation whole-body planar scans (vol 10, 7738, 2020) Kavitha, MuthuSubash; Lee, Chang-Hee; Shibudas, KattakkaliSubhashdas; Kurita, Takio; Ahn, Byeong-Cheol Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Nucl Med, Daegu, South Korea Kavitha, M.S./AAI-6438-2020; Kurita, Takio/D-8674-2012 57218147465; 57148992000; 57216692474; 7201523114; 7202791511 tkurita@hiroshima-u.ac.jp;abc2000@knu.ac.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0 2025-06-25 1 1 erratum English 2020 2020-07-09 10.1038/s41598-020-68538-6 바로가기 바로가기 바로가기 바로가기
Article Deep Learning-Based MIMO-NOMA With Imperfect SIC Decoding Nonorthogonal multiple access (NOMA) and multiple-input multiple-output (MIMO) are two key enablers for 5G systems. In this article, considering the practical issue that successive interference cancellation (SIC) decoding is imperfect in the real-world NOMA system, we propose a novel scheme for the downlink of the MIMO-NOMA system based on deep learning. In this scheme, both precoding and SIC decoding of the MIMO-NOMA system are jointly optimized (or learned) in the sense of minimizing total mean square error of the users' signals. To this end, we construct the precoder and SIC decoders using deep neural networks such that the transmitted signals intended to multiple users can be properly precoded at the transmitter based on the superposition coding technique and the received signals are accurately decodable at the users by the SIC decoding. Numerical results demonstrate the effectiveness and superior performance of the proposed scheme. Kang, Jae-Mo; Kim, Il-Min; Chun, Chang-Jae Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 41566, South Korea; Queens Univ, Dept Elect & Comp Engn, Kingston, ON K7L 3N6, Canada; Korea Electrotechnol Res Inst, Syst Control Res Ctr, Chang Won 51543, South Korea Chun, Changjae/AAF-2393-2019 56024930400; 36040390300; 55694574800 jmkang@knu.ac.kr;ilmin.kim@queensu.ca;cjchun84@gmail.com; IEEE SYSTEMS JOURNAL IEEE SYST J 1932-8184 1937-9234 14 3 SCIE COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;OPERATIONS RESEARCH & MANAGEMENT SCIENCE;TELECOMMUNICATIONS 2020 3.931 22.9 3.79 2025-06-25 73 87 Silicon carbide; Decoding; Precoding; NOMA; MIMO communication; Deep learning; Optimization; Deep learning; multiple-input multiple-output (MIMO); nonorthogonal multiple access (NOMA); neural network; precoding; successive interference cancellation (SIC) decoding Deep learning; multiple-input multiple-output (MIMO); neural network; nonorthogonal multiple access (NOMA); precoding; successive interference cancellation (SIC) decoding 5G mobile communication systems; Decoding; Deep learning; Feedback control; Mean square error; MIMO systems; Multiple access interference; Neural networks; Optimization; Silicon carbide; Telecommunication repeaters; MIMO communication; Multiple access; NOMA; Precoding; Successive interference cancellation(SIC); Deep neural networks English 2020 2020-09 10.1109/jsyst.2019.2937463 바로가기 바로가기 바로가기 바로가기
Article Deep RNN-Based Channel Tracking for Wireless Energy Transfer System In this article, we study channel tracking for a wireless energy transfer (WET) system. This problem is practically very important, but challenging. Regarding time-varying channels as a sequence to be predicted, we exploit the deep learning technique for channel tracking. Particularly, by constructing a recurrent neural network (RNN) architecture based on long short-term memory (LSTM) and feedforward neural network (FNN), we develop a novel channel tracking scheme for the WET system. This scheme sequentially estimates the channel state information (CSI) at the ET based on the previous CSI estimates and the harvested energy feedback information from the ER. Numerical results demonstrate the superior performance and effectiveness of the proposed scheme. Kang, Jae-Mo; Chun, Chang-Jae; Kim, Il-Min; Kim, Dong In Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 41566, South Korea; Korea Electrotechnol Res Inst, Ind Applicat Res Div, Chang Won 51543, South Korea; Queens Univ, Dept Elect & Comp Engn, Kingston, ON K7L 3N6, Canada; Sungkyunkwan Univ SKKU, Dept Elect & Comp Engn, Suwon 16419, South Korea ; Chun, Changjae/AAF-2393-2019; Kim, Dong/ADC-1101-2022 56024930400; 55694574800; 36040390300; 35476060100 jmkang@knu.ac.kr;cjchun84@gmail.com;ilmin.kim@queensu.ca;dikim@skku.ac.kr; IEEE SYSTEMS JOURNAL IEEE SYST J 1932-8184 1937-9234 14 3 SCIE COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;OPERATIONS RESEARCH & MANAGEMENT SCIENCE;TELECOMMUNICATIONS 2020 3.931 22.9 0.75 2025-06-25 18 21 Channel estimation; Time-varying channels; Erbium; Logic gates; Recurrent neural networks; Training; Wireless sensor networks; Channel tracking; deep learning; long short-term memory (LSTM); recurrent neural network (RNN); wireless energy transfer (WET) INFORMATION Channel tracking; deep learning; long short-term memory (LSTM); recurrent neural network (RNN); wireless energy transfer (WET) Deep learning; Energy transfer; Feedforward neural networks; Inductive power transmission; Long short-term memory; Architecture-based; Channel tracking; Energy feedbacks; Learning techniques; Numerical results; Recurrent neural network (RNN); Time varying channel; Wireless energy transfers; Channel state information English 2020 2020-09 10.1109/jsyst.2020.2975188 바로가기 바로가기 바로가기 바로가기
Article Designed ferritin nanocages displaying trimeric TRAIL and tumor-targeting peptides confer superior anti-tumor efficacy TRAIL is considered a promising target for cancer therapy because it mediates activation of the extrinsic apoptosis pathway in a tumor-specific manner by binding to and trimerizing its functional receptors, DR4 or DR5. Although recombinant human TRAIL has shown high potency and specificity for killing cancer cells in preclinical studies, it has failed in multiple clinical trials for several reasons, including a very short half-life mainly caused by instability of the monomeric form of TRAIL and rapid renal clearance of the off-targeted TRAIL. To overcome such obstacles, we developed a TRAIL-active trimer nanocage (TRAIL-ATNC) that presents the TRAIL ligand in its trimer-like conformation by connecting it to a triple helix sequence that links to the threefold axis of the ferritin nanocage. We also ligated the tumor-targeting peptide, IL4rP, to TRAIL-ATNC to enhance tumor targeting. The developed TRAIL-ATNC(IL4rP) showed enhanced agonistic activity compared with monomeric TRAIL. The in vivo serum half-life of TRAIL-ATNC(IL4rP) was similar to 16-times longer than that of native TRAIL. As a consequence of these properties, TRAIL-ATNC(IL4rP) exhibited efficacy as an anti-tumor agent in vivo against xenograft breast cancer as well as orthotopic pancreatic cancer models, highlighting the promise of this system for development as novel therapeutics against cancer. Yoo, Jae Do; Bae, Sang Mun; Seo, Junyoung; Jeon, In Seon; Vadevoo, Sri Murugan Poongkavithai; Kim, Sang-Yeob; Kim, In-San; Lee, Byungheon; Kim, Soyoun Kyungpook Natl Univ, Sch Med, Cell & Matrix Res Inst, Dept Biochem & Cell Biol, Daegu 41944, South Korea; PrismCDX Inc, 593-16 Dongtangiheung Ro, Hwaseong Si 18469, Gyeonggi Do, South Korea; Univ Ulsan, Asan Med Ctr, Asan Inst Life Sci, Coll Med, Seoul 138736, South Korea; Univ Ulsan, Dept Convergence Med, Coll Med, Seoul 05505, South Korea; Korea Inst Sci & Technol, Biomed Res Inst, Seoul 02792, South Korea; Korea Univ, KU KIST Grad Sch Converging Sci & Technol, Seoul 02841, South Korea 57216203097; 59031091500; 56573206100; 57219924195; 56663280000; 9232868900; 34770432800; 16304374900; 58847992000 soyounki@knu.ac.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.41 2025-06-25 16 17 APOPTOSIS-INDUCING LIGAND; DEATH RECEPTOR 5; COATED LEUKOCYTES; AGONIST ANTIBODY; DECOY RECEPTOR; CANCER-THERAPY; HIGH-AFFINITY; H-FERRITIN; NANOPARTICLES; PROTEIN A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Female; Ferritins; Humans; Interleukin-4 Receptor alpha Subunit; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Pancreatic Neoplasms; Peptides; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays; antineoplastic agent; ferritin; interleukin 4 receptor alpha; nanomaterial; peptide; TNFSF10 protein, human; tumor necrosis factor related apoptosis inducing ligand; A-549 cell line; animal; apoptosis; Bagg albino mouse; breast tumor; chemistry; drug effect; drug screening; female; human; male; metabolism; mouse; nude mouse; pancreas tumor; procedures; signal transduction; tumor cell line English 2020 2020-11-17 10.1038/s41598-020-77095-x 바로가기 바로가기 바로가기 바로가기
Article Development of 60-GHz millimeter wave, electromagnetic bandgap ground planes for multiple-input multiple-output antenna applications For 60-GHz band communications, both the mutual coupling and transmission distance restrict the performance of a multiple-input multiple-output (MIMO) antenna array. Several studies presented different types of meta-materials and electromagnetic bandgap (EBG) structures to improve the performance of a MIMO antenna array at the 60-GHz band. In this paper, we presented the four-element MIMO patch antenna with different types of EBG structures for the millimeter wave (mmW)communications at the 60-GHz unlicensed industrial, scientific, and medical band. The single element of the MIMO antenna array covered the mmW band from 57 GHz to 63 GHz having the dimensions of 1.3 mmx1.8 mmx0.1 mm. We developed a set of square-shaped, cross-shaped, and complex-slotted EBG ground planes between the antenna elements for the performance improvement. All the three EBG ground planes provided significant coupling reduction between the mmW MIMO antenna elements. The proposed EBG structures exhibited wide bandgap characteristics and improved scattering parameters in the desired frequency band. In contrast with the cross- and complex-slotted, the square-shaped EBG structure substantially improved the overall gain of MIMO antenna array. In addition, the square-shaped EBG reformed the maximum beam and enhanced the far-field gain pattern in the desired direction. Experimental results conducted with the fabricated prototypes showed a good agreement with the simulation results and adequately covered the 60-GHz band. The low-profile and salient features of the proposed MIMO antenna array shows the potential for on-chip applications at 60 GHz. Ullah, Sana; Yeo, Woon-Hong; Kim, Hongjoon; Yoo, Hyoungsuk Hanyang Univ, Dept Biomed Engn, Seoul 04763, South Korea; Georgia Inst Technol, George W Woodruff Sch Mech Engn, Atlanta, GA 30332 USA; Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA; Kyungpook Natl Univ, Dept Elect Engn, Daegu 41566, South Korea Yeo, Woon-Hong/G-6430-2011; ullah, sana/JQJ-1229-2023 57220646611; 25822880200; 27169635900; 25625778900 hsyoo@hanyang.ac.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 1.36 2025-06-25 28 45 MUTUAL COUPLING REDUCTION; EBG; COMPACT; ARRAY; DESIGN; SYSTEM English 2020 2020-05-22 10.1038/s41598-020-65622-9 바로가기 바로가기 바로가기 바로가기
Article Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives Although human induced pluripotent stem cell (hiPSC) lines are karyotypically normal, they retain the potential for mutation in the genome. Accordingly, intensive and relevant quality controls for clinical-grade hiPSCs remain imperative. As a conceptual approach, we performed RNA-seq-based broad-range genetic quality tests on GMP-compliant human leucocyte antigen (HLA)-homozygous hiPSCs and their derivatives under postdistribution conditions to investigate whether sequencing data could provide a basis for future quality control. We found differences in the degree of single-nucleotide polymorphism (SNP) occurring in cells cultured at three collaborating institutes. However, the cells cultured at each centre showed similar trends, in which more SNPs occurred in late-passage hiPSCs than in early-passage hiPSCs after differentiation. In eSNP karyotyping analysis, none of the predicted copy number variations (CNVs) were identified, which confirmed the results of SNP chip-based CNV analysis. HLA genotyping analysis revealed that each cell line was homozygous for HLA-A, HLA-B, and DRB1 and heterozygous for HLA-DPB type. Gene expression profiling showed a similar differentiation ability of early- and late-passage hiPSCs into cardiomyocyte-like, hepatic-like, and neuronal cell types. However, time-course analysis identified five clusters showing different patterns of gene expression, which were mainly related to the immune response. In conclusion, RNA-seq analysis appears to offer an informative genetic quality testing approach for such cell types and allows the early screening of candidate hiPSC seed stocks for clinical use by facilitating safety and potential risk evaluation. Jo, Hye-Yeong; Han, Hyo-Won; Jung, Inuk; Ju, Ji Hyeon; Park, Soon-Jung; Moon, Sunghwan; Geum, Dongho; Kim, Hyemin; Park, Han-Jin; Kim, Sun; Stacey, Glyn N.; Koo, Soo Kyung; Park, Mi-Hyun; Kim, Jung-Hyun Korea Natl Inst Hlth, Ctr Biomed Sci, Div Intractable Dis, Cheongju, South Korea; Seoul Natl Univ, Interdisciplinary Program Bioinformat, Seoul, South Korea; Kyungpook Natl Univ, Dept Comp Sci & Engn, Daegu, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Div Rheumatol, Seoul, South Korea; Konkuk Univ, Dept Med Sci, Sch Med, Seoul, South Korea; Korea Univ, Med Sch, Dept Med Sci, Seoul, South Korea; Korea Inst Toxicol, Dept Predict Toxicol, Daejeon, South Korea; Seoul Natl Univ, Bioinformat Inst, Seoul, South Korea; Seoul Natl Univ, Dept Comp Sci & Engn, 1 Gwanak Ro, Seoul 08826, South Korea; Int Stem Cell Banking Initiat, 2 High St, Barley SG8 8HZ, Herts, England; Chinese Acad Sci, Natl Stem Cell Resource Ctr, Inst Zool, Beijing 100190, Peoples R China; Chinese Acad Sci, Innovat Acad Stem Cell & Regenerat, Beijing 100101, Peoples R China Moon, Shin-Yong/J-5467-2012; Park, Mi-Hyun/AAP-9591-2020 57158666600; 16068377900; 56067575500; 13006657900; 56523600800; 7401616696; 6602423415; 57196215834; 7601566663; 36063436900; 7102445556; 7102367881; 17135830200; 57865585600 mihyun4868@korea.kr;kjhcorea@korea.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.68 2025-06-25 28 26 COPY NUMBER; RNA; GENERATION; IPSCS; DIFFERENTIATION; MODULATION; DISCOVERY; FRAMEWORK; GENOME; GROWTH Cell Differentiation; Cell Line; Cellular Reprogramming; DNA Copy Number Variations; Genotype; Histocompatibility Testing; Homozygote; Humans; Induced Pluripotent Stem Cells; Karyotyping; RNA-Seq; Transcriptome; transcriptome; cell differentiation; cell line; copy number variation; cytology; genetics; genotype; histocompatibility test; homozygote; human; induced pluripotent stem cell; karyotyping; nuclear reprogramming; physiology English 2020 2020-03-03 10.1038/s41598-020-60466-9 바로가기 바로가기 바로가기 바로가기
Article Dynamic and subtype-specific interactions between tumour burden and prognosis in breast cancer We investigated the relationship between the prognostic importance of anatomic tumour burden and subtypes of breast cancer using data from the Korean Breast Cancer Registry Database. In HR+/HER2+ and HR-/HER2-tumours, an increase in T stage profoundly increased the hazard of death, while the presence of lymph node metastasis was more important in HR+/HER2+ and HR-/HER2+ tumours among 131,178 patients with stage I-III breast cancer. The patterns of increasing mortality risk and tumour growth (per centimetre) and metastatic nodes (per node) were examined in 67,038 patients with a tumour diameter 3 or 4 nodes. The interactions between the prognostic significance of anatomic tumour burden and subtypes were significant. The prognostic relevance of the anatomic tumour burden was non-linear and highly dependent on the subtypes of breast cancer. Lee, S. B.; Kim, H. -K.; Choi, Y.; Ju, Y. W.; Lee, H. -B.; Han, W.; Noh, D. -Y.; Son, B. H.; Ahn, S. H.; Kim, K. S.; Nam, S. J.; Kim, E. -K.; Park, H. Y.; Park, W. -C.; Lee, J. W.; Moon, H. -G. Univ Ulsan, Coll Med, Asan Med Ctr, Div Breast Surg,Dept Surg, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea; Seoul Natl Univ, Dept Surg, Coll Med, 28 Yongon Dong, Seoul 110744, South Korea; Korea Univ, Coll Med, Anam Hosp, Dept Surg,Div Breast & Endocrine Surg, Seoul, South Korea; Seoul Natl Univ Hosp, Med Res Collaborating Ctr, Seoul, South Korea; Ulsan City Hosp, Breast Thyroid Ctr, Ulsan, South Korea; Samsung Med Ctr, Dept Surg, Div Breast Surg, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Surg, Seongnam, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea; Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Dept Surg, Seoul, South Korea ; Lee, Jong-Seok/J-5603-2012; Lee, Dong-Hyeon/AAM-3893-2021; Kim, Seunghyun/AAA-3402-2022; Moon, Hyeong-Gon/G-7724-2011; Kim, Sanghoon/ABA-6994-2020 56556623100; 57199392663; 54779538700; 57216654759; 56460556800; 8588073500; 7101800569; 26028949200; 55648899200; 23019357600; 7402276023; 24829042700; 56564377200; 56067764000; 55992285000; 9635399700 jjjongwr@hanmail.net;moonhg74@snu.ac.kr; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.18 2025-06-25 5 5 LYMPH-NODE STATUS; 20-YEAR FOLLOW-UP; GROWTH-FACTOR-C; STAGING SYSTEM; SURVIVAL; SIZE; MASTECTOMY; RECEPTOR; BASAL; CHEMOTHERAPY Adolescent; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metastasis; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Tumor Burden; Young Adult; epidermal growth factor receptor 2; ERBB2 protein, human; estrogen receptor; progesterone receptor; tumor marker; adolescent; adult; aged; breast tumor; classification; female; follow up; human; metabolism; metastasis; middle aged; multimodality cancer therapy; pathology; prognosis; survival rate; tumor volume; young adult English 2020 2020-09-22 10.1038/s41598-020-72033-3 바로가기 바로가기 바로가기 바로가기
Article Eclogite resembling metamorphic disequilibrium assemblage formed through fluid-induced metasomatic reactions Equilibrium omphacite-garnet-bearing mafic rocks have been classified as eclogites, either pristine or retrogressed, that were formed at great depths in the lithosphere. Here we report a unique natural example of eclogite resembling assemblage in disequilibrium formed through fluid-induced metasomatic reactions under the amphibolite to granulite facies. Primarily, the amphibolized protolith experienced a garnet-amphibolite facies metamorphism at similar to 500-700 degrees C and similar to 0.8-1 GPa. Subsequently, CO2 fluid induced fracturing and dissolution-reprecipitation reactions occurred at peak metamorphic conditions of similar to 700 degrees C and similar to 1 GPa. Occasional omphacite-albite assemblage, which gradually replace diopside-oligoclase symplectite adjacent to albite veins along fractures, indicates fluid-induced coupled dissolution-reprecipitation disequilibrium reactions. Here the albite-omphacite assemblage is in local equilibrium at least on 1 mm length scale, during cooling, below similar to 600 degrees C and similar to 1 GPa, within the amphibolite facies conditions. The results from this study clearly suggest that disequilibrium garnet-omphacite assemblage in mafic rocks could be formed by crustal reworking processes below granulite facies conditions, and their textural equilibrium is an important criterion while defining eclogite facies. Kwon, Sanghoon; Samuel, Vinod O.; Song, Yungoo; Kim, Sung Won; Park, Seung-Ik; Jang, Yirang; Santosh, M. Yonsei Univ, Dept Earth Syst Sci, Seoul 03722, South Korea; Korea Inst Geosci & Mineral Resources, Geol Div, Daejeon 34132, South Korea; Kyungpook Natl Univ, Dept Geol, Daegu 41566, South Korea; Chonnam Natl Univ, Dept Earth & Environm Sci, Gwangju 61186, South Korea; China Univ Geosci Beijing, Sch Earth Sci & Resources, 29 Xueyuan Rd, Beijing 100083, Peoples R China; Univ Adelaide, Dept Earth Sci, Adelaide, SA, Australia ; Kim, Sung/U-2460-2017; Santosh, M/B-2563-2012 7402624141; 56068101600; 7404920759; 50561745800; 55832472000; 55366462500; 57531732700 vosamuel@gmail.com; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.32 2025-06-25 8 10 SUBSOLIDUS PHASE-RELATIONS; PERMO-TRIASSIC COLLISION; SUBDUCTION-ZONE; CONTINENTAL-CRUST; MIXING PROPERTIES; SOUTH-KOREA; BELT; EVOLUTION; EXHUMATION; TECTONICS English 2020 2020-11-16 10.1038/s41598-020-76999-y 바로가기 바로가기 바로가기 바로가기
Article Effect of the submandibular push exercise using visual feedback from pressure sensor: an electromyography study We developed a new exercise method called the submandibular push exercise that can strengthen the suprahyoid muscle by inducing only the motion of the hyoid bone without neck flexion. In this study, we aimed to investigate and compare the muscle activity of the suprahyoid and infrahyoid muscles in the course of performing three different swallowing exercises. Twenty healthy participants and fifteen patients with dysphagia were recruited. Each participant consecutively performed three exercises: Shaker, CTAR, and submandibular push exercises. To investigate muscle activation, surface electromyography was performed on the suprahyoid, infrahyoid, and SCM muscles, during the exercises. Root mean square (RMS) was measured. In healthy participants, the submandibular push exercise showed a significantly higher RMS value in the suprahyoid and infrahyoid muscles than the Shaker and CTAR exercises using repeated ANOVA with Tukey's post hoc test (p<0.05). In patients with dysphagia, the submandibular push and Shaker exercises showed significantly higher RMS value in the suprahyoid and infrahyoid muscles than the CTAR exercise. However, no significant difference was found between the submandibular push and Shaker exercises. In both healthy and patients with dysphagia, the mean RMS values of the SCM muscles during the submandibular push exercise were significantly lower than those during the Shaker exercise using repeated ANOVA with Tukey's post hoc test (p<0.05). In conclusion, considering the relatively superior selectiveness in suprahyoid and infrahyoid muscle contraction, the submandibular push exercise using visual feedback from pressure sensor could be an efficient supplementary exercise to the conventional swallowing muscle exercises. However, further studies may be necessary to confirm the improvement in swallowing difficulty. Park, Sungwon; Cho, Joo Young; Lee, Byung Joo; Hwang, Jong-Moon; Lee, Myunghwan; Hwang, Soo Yeon; Kim, KwanMyung; Lee, Ki Hoon; Park, Donghwi Daegu Fatima Hosp, Dept Rehabil Med, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Dept Rehabil Med, Daegu, South Korea; Daegu Gyeongbuk Med Innovat Fdn, Med Device Dev Ctr, Daegu, South Korea; Ulsan Natl Inst Sci & Technol, Grad Sch Creat Design Engn, Ulsan, South Korea; Mompyeonhan Rehabil Clin, Daegu, South Korea; Univ Ulsan, Coll Med, Ulsan Univ Hosp, Dept Phys Med & Rehabil, 877 Bangeojinsunhwando Ro, Ulsan 44033, South Korea CHO, JOO/AAJ-2012-2020; Park, Donghwi/GYQ-6185-2022 57211828460; 57211083171; 57202436497; 56367634000; 57218160708; 57218168884; 55339231200; 57218161131; 56606561400 bdome@hanmail.net; SCIENTIFIC REPORTS SCI REP-UK 2045-2322 10 1 SCIE MULTIDISCIPLINARY SCIENCES 2020 4.38 22.9 0.32 2025-06-25 49 11 SURFACE ELECTROMYOGRAPHY; CHIN TUCK; ELECTRICAL-STIMULATION; RESISTANCE CTAR; HEAD LIFT; MUSCLES; DYSPHAGIA; MOVEMENT Adult; Deglutition Disorders; Electromyography; Exercise Therapy; Feedback, Sensory; Female; Humans; Male; Muscle Strength; Neck Muscles; Resistance Training; Treatment Outcome; Young Adult; adult; dysphagia; electromyography; female; human; kinesiotherapy; male; muscle strength; neck muscle; physiology; procedures; resistance training; sensory feedback; treatment outcome; young adult English 2020 2020-07-16 10.1038/s41598-020-68738-0 바로가기 바로가기 바로가기 바로가기
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KeywordsPlus (WoS) Web of Science에서 자동으로 추출한 추가 키워드입니다. 논문의 참고문헌 제목에서 자주 등장하는 단어들로 생성됩니다.
Keywords (SCOPUS) 저자가 논문에서 직접 지정한 키워드입니다. SCOPUS에 등록된 저자 키워드 목록입니다.
KeywordsPlus (SCOPUS) SCOPUS에서 자동으로 추출하거나 추가한 색인 키워드입니다.
Language 논문이 작성된 언어입니다. 대부분 English이며, 그 외 다양한 언어로 작성된 논문이 포함될 수 있습니다.
Publication Year 논문이 출판된 연도입니다.
Publication Date 논문의 정확한 출판 날짜입니다 (년-월-일 형식).
DOI Digital Object Identifier. 디지털 객체 식별자로, 논문을 고유하게 식별하는 영구적인 식별번호입니다. 이를 통해 논문의 온라인 위치를 찾을 수 있습니다.