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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Managing hydrogen bonding in the clathrate hydrate of the 1-pentanol guest molecule | It remains a difficult task to predict the hydrate structure and conformation of potential guest molecules in one of the three canonical hydrate lattices. 1-Pentanol is characteristic of molecules that lie at the margin of suitability as a guest molecule for the structure II hydrate phase, both because of its size and the presence of a hydrophilic OH group that tends to destabilize the clathrate hydrate framework. To manage the destabilizing influence of guest-host hydrogen bonding, some years ago a more robust framework was developed by doping the hydrate with NH4+ and F- ions in order to direct the guest hydrophilic groups away from the cage water molecules. Attempts to enclathrate 1-pentanol in the NH4F doped clathrate were successful, but, surprisingly, the clathrate, as determined by PXRD, proved to be structure II (sII), even though the 1-pentanol appears to be too large to fit the pseudo-spherical 5(12)6(4) cage. This suggested that the doped clathrate not only managed the guest-host hydrogen bonding network, but also forced the guest into a very compact conformation to fit the pseudospherical sII large cage (5(12)6(4)). These features were investigated further with C-13 NMR and molecular dynamics simulations to identify the most likely guest conformation of 1-pentanol in the sII large cage. | Lee, Byeonggwan; Kim, Jeongtak; Shin, Kyuchul; Park, Ki Hun; Cha, Minjun; Alavi, Saman; Ripmeester, John A. | Kyungpook Natl Univ, Dept Hydrogen & Renewable Energy, Daegu 41566, South Korea; Korea Atom Energy Res Inst, Radioact Waste Treatment Res Team, Daejeon 34057, South Korea; Kyungpook Natl Univ, Dept Appl Chem, Daegu 41566, South Korea; Korea Inst Energy Res, Climate Change Res Div, Daejeon 34129, South Korea; Kangwon Natl Univ, Dept Energy & Resources Engn, Gangwon Do 24341, South Korea; Univ Ottawa, Dept Chem & Biomol Sci, Ottawa, ON K1N 6N5, Canada; Natl Res Council Canada, 100 Sussex Dr, Ottawa, ON K1A 0R6, Canada | Ripmeester, John/G-1950-2011; Lee, Byeonggwan/HPD-2363-2023; Alavi, Saman/A-1373-2012 | 57201269846; 57204511907; 14030501800; 57208240254; 23666652400; 7005887421; 7102709932 | kyuchul.shin@knu.ac.kr;salavish@uottawa.ca; | CRYSTENGCOMM | CRYSTENGCOMM | 1466-8033 | 23 | 26 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CRYSTALLOGRAPHY | 2021 | 3.756 | 21.2 | 0.52 | 2025-07-30 | 8 | 8 | STRUCTURE-II; SPECTROSCOPIC OBSERVATION; FORCE-FIELD; METHANE; WATER; IDENTIFICATION; CONFIRMATION; SIMULATION; DYNAMICS | Conformations; Hydration; Hydrogen; Hydrogen bonds; Hydrophilicity; Molecular dynamics; Molecules; Clathrate hydrate; Destabilizing influences; Guest molecules; Hydrate structures; Hydrogen bonding network; Hydrophilic groups; Molecular dynamics simulations; Water molecule; Hydrates | English | 2021 | 2021-07-14 | 10.1039/d1ce00583a | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Resveratrol enhances bone formation by modulating inflammation in the mouse periodontitis model | Objective To evaluate the effect of resveratrol on periodontal bone regeneration after local delivery and to determine its effect on inflammatory mediators. Background Resveratrol is considered an anti-inflammatory polyphenolic stilbene involved in the modulation of inflammation. Materials and Methods Periodontitis was induced in mouse molars using a 5-day ligature model followed by the left second molar extraction and 50 mu M resveratrol treatment for 1 and 2 weeks. We then examined specimens treated for 1 week histologically and with immunostaining. Microfocus-computed tomography (micro-CT) was used to examine the bone volume formation. Results After 1 week of treatment, proinflammatory cytokine levels (TNF-alpha and IL6), cells exhibiting neutrophil and macrophage marker (MPO), cell proliferation marker (Ki67), and preosteoblastic marker (RUNX2) reactivity decreased in the resveratrol-treated specimens compared to the control group. In contrast, we observed a higher number of CD31-, F4/80-, and osteocalcin- (OCN-) positive cells in the resveratrol-treated specimens. After 2 weeks, micro-CT confirmed an increased bone mass in the region of the extraction socket in the resveratrol-treated group. Conclusion After 1 week, the resveratrol-treated specimens revealed evidence of inflammation modulation compared to the control group. These data suggest that resveratrol not only affects inflammation control but also is useful for treating periodontitis-related tissue defects and bone regeneration. | Adhikari, Nirpesh; Prasad Aryal, Yam; Jung, Jae-Kwang; Ha, Jung-Hong; Choi, So-Young; Kim, Ji-Youn; Lee, Tae-Hoon; Kim, Sang-Hyun; Yamamoto, Hitoshi; Suh, Jo-Young; An, Chang-Hyeon; Lee, Youngkyun; Sohn, Wern-Joo; An, Seo-Young; Kim, Jae-Young | Kyungpook Natl Univ, Sch Dent, Dept Biochem, IHBR, 2177 Dalgubeol Daero, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Oral Med, IHBR, Daegu, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Conservat Dent, IHBR, Daegu, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, IHBR, Daegu, South Korea; Gachon Univ, Coll Hlth Sci, Dept Dent Hyg, Incheon, South Korea; Chonnam Natl Univ, Dept Oral Biochem, Dent Sci Res Inst, Sch Dent,Med Res Ctr Biomineralizat Disorders, Gwangju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Daegu, South Korea; Tokyo Dent Coll, Dept Histol & Dev Biol, Tokyo, Japan; Kyungpook Natl Univ, Sch Dent, Dept Periodontol, IHBR, Daegu, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Oral & Maxillofacial Radiol, IHBR, Daegu, South Korea; Daegu Haany Univ, Div Biotechnol & Convergence, Gyongsan, South Korea | ; Adhikari, Nirpesh/KEJ-4658-2024; Kim, Ji-Youn/A-5779-2017 | 57190967936; 57220078959; 55970994400; 55549831900; 57202918688; 57157491000; 57198752094; 57210450420; 55725330600; 7201514992; 17134437600; 36062942200; 44161404800; 55258203200; 56812734700 | jykim91@knu.ac.kr; | JOURNAL OF PERIODONTAL RESEARCH | J PERIODONTAL RES | 0022-3484 | 1600-0765 | 56 | 4 | SCIE | DENTISTRY, ORAL SURGERY & MEDICINE | 2021 | 3.946 | 21.2 | 1.76 | 2025-07-30 | 19 | 22 | bone regeneration; cytokine; inflammation; periodontitis model; tooth loss | MESENCHYMAL STEM-CELLS; PATHOGENESIS; METABOLISM; RESOLUTION | bone regeneration; cytokine; inflammation; periodontitis model; tooth loss | Alveolar Bone Loss; Animals; Disease Models, Animal; Inflammation; Mice; Osteogenesis; Periodontitis; Resveratrol; resveratrol; alveolar bone loss; animal; bone development; diagnostic imaging; disease model; inflammation; mouse; periodontitis | English | 2021 | 2021-08 | 10.1111/jre.12870 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Review | Vanadium oxide bronzes as cathode active materials for non-lithium-based batteries | Vanadium oxide bronzes have recently been considered battery cathode materials owing to their inherent large interlayer distance for facile intercalation processes, mixed valences that can potentially provide high capacity, and good electronic conductivity. Vanadium oxide bronzes have been tested as cathodes mostly for lithium-based batteries but relatively fewer studies have been performed for non-lithium-based batteries. In this review, we look at the recent developments and approaches made by multiple battery research groups in using vanadium oxide bronzes as cathode active materials for non-lithium-based batteries. Several aspects of various vanadium oxide bronzes were elucidated in relation to the crystal structure and their interaction with other battery components. The electrochemical performances of batteries were then compared. © The Royal Society of Chemistry 2021. | Esparcia, Eugene; Joo, Jin; Lee, Jinwoo | Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea; Department of Applied Chemistry, School of Engineering, Kyungpook National University (KNU), 80 Daehak-ro, Buk-gu, Daegu, 41566, South Korea; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, South Korea | 57202046742; 57189617034; 56007027600 | joojin@knu.ac.kr; | CrystEngComm | CRYSTENGCOMM | N/A | 1466-8033 | 23 | 31 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CRYSTALLOGRAPHY | 2021 | 3.756 | 21.2 | 0.15 | 2025-07-30 | 7 | Bronze; Cathodes; Crystal structure; Lithium; Lithium batteries; Oxides; Cathode active material; Electrochemical performance; Electronic conductivity; Intercalation process; Interlayer distance; Mixed valence; Research groups; Vanadium oxide bronze; Vanadium compounds | English | Final | 2021 | 10.1039/d1ce00339a | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | Needs for Increased Awareness of Gastrointestinal Manifestations in Patients With Human Inborn Errors of Immunity | The gastrointestinal (GI) tract is frequently affected by inborn errors of immunity (IEI), and GI manifestations can be present in IEI patients before a diagnosis is confirmed. We aimed to investigate clinical features, endoscopic and histopathologic findings in IEI patients. This was a retrospective cohort study conducted from 1995 to 2020. Eligible patients were diagnosed with IEI and had GI manifestations that were enough to require endoscopies. IEI was classified according to the International Union of Immunological Societies classification. Of 165 patients with IEI, 55 (33.3%) had GI manifestations, and 19 (11.5%) underwent endoscopy. Among those 19 patients, nine (47.4%) initially presented with GI manifestations. Thirteen patients (68.4%) were male, and the mean age of patients 11.5 +/- 7.9 years (range, 0.6 - 26.6) when they were consulted and evaluated with endoscopy. The most common type of IEI with severe GI symptoms was "Disease of immune dysregulation" (31.6%) followed by "Phagocyte defects" (26.3%), according to the International Union of Immunological Societies classification criteria. Patients had variable GI symptoms such as chronic diarrhea (68.4%), hematochezia (36.8%), abdominal pain (31.6%), perianal disease (10.5%), and recurrent oral ulcers (10.5%). During the follow-up period, three patients developed GI tract neoplasms (early gastric carcinoma, mucosa associated lymphoid tissue lymphoma of colon, and colonic tubular adenoma, 15.8%), and 12 patients (63.2%) were diagnosed with inflammatory bowel disease (IBD)-like colitis. Investigating immunodeficiency in patients with atypical GI symptoms can provide an opportunity for correct diagnosis and appropriate disease-specific therapy. Gastroenterologists and immunologists should consider endoscopy when atypical GI manifestations appear in IEI patients to determine if IBD-like colitis or neoplasms including premalignant and malignant lesions have developed. Also, if physicians in various fields are better educated about IEI-specific complications, early diagnosis and disease-specific treatment for IEI will be made possible. | Kim, Eun Sil; Kim, Dongsub; Yoon, Yoonsun; Kwon, Yiyoung; Park, Sangwoo; Kim, Jihyun; Ahn, Kang Mo; Ahn, Soomin; Choe, Yon Ho; Kim, Yae-Jean; Kim, Mi Jin | Sungkyunkwan Univ, Samsung Med Ctr, Dept Pediat, Sch Med, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Pediat, Daegu, South Korea; Korea Univ, Guro Hosp, Coll Med, Dept Pediat, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Pathol, Sch Med, Seoul, South Korea | Kim, Youngmin/C-7926-2019; Yoon, Yoonsun/AAI-9275-2021; Kim, Mi Jin/GXH-9639-2022; Kim, Yong-Jae/JQW-5758-2023; Kim, Nam-Joong/J-2735-2012 | 57205500267; 57205248455; 57217112409; 57211905573; 57237404600; 55868146800; 7202870689; 54893655800; 21333712100; 7410198066; 56638815200 | yaejean.kim@samsung.com;mijin1217.kim@samsung.com; | FRONTIERS IN IMMUNOLOGY | FRONT IMMUNOL | 1664-3224 | 12 | SCIE | IMMUNOLOGY | 2021 | 8.787 | 21.3 | 0.25 | 2025-07-30 | 7 | 5 | inborn errors of immunity; primary immunodeficiencies; gastrointestinal; endoscopy; malignancy; inflammatory bowel disease | PRIMARY IMMUNODEFICIENCY DISEASES; THROMBOCYTOPENIC PURPURA; ULCERATIVE-COLITIS; CANCER; DEFICIENCY; FEATURES; CHILDREN | endoscopy; gastrointestinal; inborn errors of immunity; inflammatory bowel disease; malignancy; primary immunodeficiencies | Adolescent; Adult; Child; Child, Preschool; Cohort Studies; Female; Gastrointestinal Diseases; Humans; Immunologic Deficiency Syndromes; Infant; Male; Retrospective Studies; Young Adult; cytotoxic T lymphocyte antigen 4; abdominal pain; anemia; anorexia; Article; autoinflammatory disease; awareness; child; chronic diarrhea; clinical feature; cohort analysis; Crohn disease; endoscopy; esophagogastroduodenoscopy; female; follow up; gastrointestinal symptom; gastrointestinal tumor; histopathology; hospitalization; human; human cell; ileocolonoscopy; immune deficiency; immune dysregulation; infant; inflammatory bowel disease; major clinical study; male; phagocyte; rectum hemorrhage; retrospective study; sigmoidoscopy; ulcerative colitis; adolescent; adult; complication; gastrointestinal disease; immune deficiency; pathology; preschool child; young adult | English | 2021 | 2021-08-12 | 10.3389/fimmu.2021.698721 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Non-Invasive Diagnosis for Acute Rejection Using Urinary mRNA Signature Reflecting Allograft Status in Kidney Transplantation | Urine has been regarded as a good resource based on the assumption that urine can directly reflect the state of the allograft or ongoing injury in kidney transplantation. Previous studies, suggesting the usefulness of urinary mRNA as a biomarker of acute rejection, imply that urinary mRNA mirrors the transcriptional activity of the kidneys. We selected 14 data-driven candidate genes through a meta-analysis and measured the candidate genes using quantitative PCR without pre-amplification in the cross-sectional specimens from Korean kidney transplant patients. Expression of 9/14 genes (CXCL9, CD3 epsilon, IP-10, LCK, C1QB, PSMB9, Tim-3, Foxp3, and FAM26F) was significantly different between acute rejection and stable graft function with normal pathology and long-term graft survival in 103 training samples. CXCL9 was also distinctly expressed in allografts with acute rejection in in situ hybridization analysis. This result, consistent with the qPCR result, implies that urinary mRNA could reflect the magnitude of allograft injury. We developed an AR prediction model with the urinary mRNAs by a binary logistic regression and the AUC of the model was 0.89 in the training set. The model was validated in 391 independent samples, and the AUC value yielded 0.84 with a fixed manner. In addition, the decision curve analysis indicated a range of reasonable threshold probabilities for biopsy. Therefore, we suggest the urine mRNA signature could be used as a non-invasive monitoring tool of acute rejection for clinical application and could help determine whether to perform a biopsy in a recipient with increased creatinine. | Seo, Jung-Woo; Lee, Yu Ho; Tae, Dong Hyun; Park, Seon Hwa; Moon, Ju-Young; Jeong, Kyung Hwan; Kim, Chan-Duck; Chung, Byung Ha; Park, Jae Berm; Kim, Yeong Hoon; Seok, Junhee; Joo, Sun Hyung; Lee, Seung Hwan; Lee, Jong Soo; Lee, Sang-Ho | Kyung Hee Univ Hosp Gangdong, Med Sci Inst, Dept Core Res Lab, Seoul, South Korea; Kyung Hee Univ Hosp Gangdong, Div Nephrol, Dept Internal Med, Seoul, South Korea; Korea Univ, Sch Elect Engn, Seoul, South Korea; Kyung Hee Univ, Coll Med, Div Nephrol, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Nephrol, Daegu, Daegu, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Internal Med,Div Nephrol, Seoul, South Korea; Sungkyunkwan Univ, Samsung Hosp, Dept Surg, Seoul, South Korea; Inje Univ, Busan Paik Hosp, Div Nephrol, Dept Internal Med,Coll Med, Busan, South Korea; Kyung Hee Univ Hosp Gangdong, Dept Surg, Seoul, South Korea; Univ Ulsan, Coll Med, Div Nephrol, Dept Internal Med, Ulsan, South Korea | ; Kim, Tae-Hee/AAN-9079-2021; , Prof/W-5371-2019; Moon, Ju-Young/T-6959-2019; Kim, Hyoungnae/JXN-1329-2024 | 56678212900; 56344334200; 57194702774; 57193847481; 7403231326; 8443579300; 8558530700; 57201863822; 13605451500; 7410196419; 24069490100; 25928515100; 55989532800; 57201264463; 55890136000 | lshkidney@khu.ac.kr; | FRONTIERS IN IMMUNOLOGY | FRONT IMMUNOL | 1664-3224 | 12 | SCIE | IMMUNOLOGY | 2021 | 8.787 | 21.3 | 0.45 | 2025-07-30 | 8 | 9 | kidney; transplantation; non-invasive diagnosis; acute rejection; urinary mRNA | CD4(+) T-CELLS; HIGH EXPRESSION; PREAMPLIFICATION; RECIPIENTS; BLOOD; TIM-3; CXCL9; ASSAY | acute rejection; kidney; non-invasive diagnosis; transplantation; urinary mRNA | Acute Disease; Adult; Allografts; Biomarkers; Cell-Free Nucleic Acids; Female; Graft Rejection; Humans; Immunohistochemistry; Kidney Transplantation; Liquid Biopsy; Male; Middle Aged; Reproducibility of Results; RNA, Messenger; ROC Curve; basiliximab; calcineurin inhibitor; CXCL9 chemokine; cyclosporine; gamma interferon inducible protein 10; mammalian target of rapamycin inhibitor; mycophenolate mofetil; steroid; tacrolimus; thymocyte antibody; transcription factor FOXP3; biological marker; cell free nucleic acid; messenger RNA; acute graft rejection; acute kidney tubule necrosis; adult; Article; biopsy; CD3 epsilon gene; Complement C1q B Chain gene; controlled study; diagnostic test accuracy study; estimated glomerular filtration rate; family with sequence similarity 26 gene; female; glomerulus filtration rate; human; human tissue; immunosuppressive treatment; in situ hybridization; kidney biopsy; kidney transplantation; major clinical study; male; middle aged; non invasive measurement; Proteasome 20S Subunit Beta 9 gene; real time polymerase chain reaction; sensitivity and specificity; urine sampling; acute disease; adverse event; allograft; genetics; graft rejection; immunohistochemistry; immunology; kidney transplantation; liquid biopsy; procedures; receiver operating characteristic; reproducibility; urine | English | 2021 | 2021-06-10 | 10.3389/fimmu.2021.656632 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Declining trend of preemptive kidney transplantation and impact of pretransplant dialysis: a Korean nationwide prospective cohort study | We evaluated the temporal trend of preemptive kidney transplantation (KT) and the effect of pretransplant dialysis duration on post-transplant outcomes. This was a nationwide cohort study of the first-time 3392 living donor KT (LDKT) recipients (2014-2019). The annual changes in proportion of preemptive KT, factors associated with preemptive KT, and post-transplant outcomes were analyzed. Preemptive KT was performed in 816 (24.1%) patients. Annual trend analysis revealed gradual decrease in preemptive KT over time (P = 0.042). Among the underlying causes of preemptive KT, the proportion of diabetes increased and that of glomerulonephritis decreased during the study period. Glomerulonephritis as the primary renal disease was a predictor of preemptive KT. Patients with pretransplant dialysis >6 months showed increased graft failure risk than preemptive KT in the subdistribution of hazard model for competing risk (adjusted hazard ratio [aHR], 2.53; 95% confidence interval [CI], 1.09-5.87; P = 0.031) and in propensity score-matched analysis (aHR, 2.45; 95% CI, 1.02-5.92; P = 0.034); however, pretransplant dialysis <= 6 months showed comparable graft survival with preemptive KT in both analyses. Preemptive KT declined over successive years, associated with an increase in diabetes and a decrease in glomerulonephritis as underlying causes of KT. Short period of dialysis less than 6 months does not affect graft survival compared with preemptive KT; however, longer dialysis decreases graft survival. | Lim, Jeong-Hoon; Jeon, Yena; Lee, Sang-Ho; Lee, Yu Ho; Lee, Jung Pyo; Yang, Jaeseok; Kim, Myoung Soo; Jung, Hee-Yeon; Choi, Ji-Young; Park, Sun-Hee; Kim, Chan-Duck; Kim, Yong-Lim; Cho, Jang-Hee | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Kyung Hee Univ, Dept Internal Med, Div Nephrol, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Internal Med, Div Nephrol, Seongnam, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Div Nephrol, Coll Med, Seoul, South Korea; Yonsei Univ, Dept Surg, Coll Med, Seoul, South Korea | Cho, Jang-hee/ABD-3534-2020; Lim, Jeong-Hoon/ABE-6003-2020; Kim, Seung-Ki/J-2742-2012; Yang, Jae/LUW-8250-2024; Park, Sun-Hee/LMN-0033-2024; Kim, Yong-Lim/AGK-3172-2022; Lee, Jun-Young/N-5963-2019 | 55360244300; 57209909350; 55890136000; 56344334200; 56028990400; 57212326527; 35268871600; 57196396467; 7501393222; 7501831741; 8558530700; 55633533600; 7403536291 | jh-cho@knu.ac.kr; | TRANSPLANT INTERNATIONAL | TRANSPL INT | 0934-0874 | 1432-2277 | 34 | 12 | SCIE | SURGERY;TRANSPLANTATION | 2021 | 3.842 | 21.4 | 0.36 | 2025-07-30 | 3 | 3 | living donor kidney transplantation; mortality; preemptive kidney transplantation; renal outcome; trends | STAGE RENAL-DISEASE; DIABETES-MELLITUS; UNITED-STATES; RECIPIENTS; RATES; SURVIVAL; HAZARDS | Cohort Studies; Graft Survival; Humans; Kidney Failure, Chronic; Kidney Transplantation; Prospective Studies; Renal Dialysis; Republic of Korea; Retrospective Studies; Treatment Outcome; basiliximab; corticosteroid; mycophenolic acid; sirolimus; tacrolimus; thymocyte antibody; adult; Article; clinical feature; clinical outcome; comorbidity; controlled study; diabetes mellitus; dialysis; female; glomerulonephritis; graft failure; graft rejection; graft survival; human; human tissue; kidney disease; kidney transplantation; living donor; major clinical study; male; mortality; postoperative period; prediction; preemptive therapy; preoperative care; propensity score; prospective study; risk; South Korea; temporal analysis; treatment duration; trend study; chronic kidney failure; cohort analysis; hemodialysis; retrospective study; treatment outcome | English | 2021 | 2021-12 | 10.1111/tri.14135 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Impact of recipient and donor smoking in living-donor kidney transplantation: a prospective multicenter cohort study | The smoking status of kidney transplant recipients and living donors has not been explored concurrently in a prospective study, and the synergistic adverse impact on outcomes remains uncertain. The self-reported smoking status and frequency were obtained from recipients and donors at the time of kidney transplantation in a prospective multicenter longitudinal cohort study (NCT02042963). Smoking status was categorized as "ever smoker" (current and former smokers collectively) or "never smoker." Among 858 eligible kidney transplant recipients and the 858 living donors, 389 (45.3%) and 241 (28.1%) recipients were considered ever smokers at the time of transplant. During the median follow-up period of 6 years, the rate of death-censored graft failure was significantly higher in ever-smoker recipients than in never-smoker recipients (adjusted HR, 2.82; 95% CI 1.01-7.87; P = 0.048). A smoking history of >20 pack-years was associated with a significantly higher rate of death-censored graft failure than a history of <= 20 pack-years (adjusted HR, 2.83; 95% CI 1.19-6.78; P = 0.019). No donor smoking effect was found in terms of graft survival. The smoking status of the recipients and donors or both did not affect the rate of biopsy-proven acute rejection, major adverse cardiac events, all-cause mortality, or post-transplant diabetes mellitus. Taken together, the recipient's smoking status before kidney transplantation is dose-dependently associated with impaired survival. | Jung, Hee-Yeon; Jeon, Yena; Ha Huh, Kyu; Park, Jae Berm; Jung, Cheol Woong; Lee, Sik; Han, Seungyeup; Ro, Han; Yang, Jaeseok; Ahn, Curie; Cho, Jang-Hee; Park, Sun-Hee; Kim, Yong-Lim; Kim, Chan-Duck | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Yonsei Univ, Dept Surg, Coll Med, Seoul, South Korea; Sungkyunkwan Univ, Seoul Samsung Med Ctr, Dept Surg, Seoul, South Korea; Korea Univ, Dept Surg, Coll Med, Seoul, South Korea; Chonbuk Natl Univ Hosp, Dept Internal Med, Jeonju, South Korea; Keimyung Univ, Dept Internal Med, Sch Med, Daegu, South Korea; Gachon Univ, Gil Hosp, Dept Internal Med, Incheon, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea | Cho, Jang-hee/ABD-3534-2020; Kim, Yong-Lim/AGK-3172-2022; Jung, Hee-Yeon/AFB-8578-2022; Park, Sun-Hee/LMN-0033-2024; Han, Seung Seok/HGD-2825-2022; Yang, Jae/LUW-8250-2024 | 57196396467; 57209909350; 35183155900; 13605451500; 7402016375; 57192521521; 24281360600; 26538034700; 57212326527; 7201986669; 7403536291; 7501831741; 55633533600; 8558530700 | hy-jung@knu.ac.kr;drcdkim@knu.ac.kr; | TRANSPLANT INTERNATIONAL | TRANSPL INT | 0934-0874 | 1432-2277 | 34 | 12 | SCIE | SURGERY;TRANSPLANTATION | 2021 | 3.842 | 21.4 | 0.12 | 2025-07-30 | 3 | 3 | graft survival; kidney transplantation; living donors; smoking; transplant recipient | CIGARETTE-SMOKING; RENAL-FUNCTION; HUMAN COSTS; RISK; PROGRESSION; FAILURE; DISEASE | Graft Rejection; Graft Survival; Humans; Kidney Transplantation; Living Donors; Longitudinal Studies; Prospective Studies; Smoking; cytokine receptor antagonist; thymocyte antibody; acute graft rejection; adult; all cause mortality; Article; cohort analysis; continuing smoker; diabetes mellitus; ex-smoker; female; follow up; graft failure; graft recipient; graft survival; human; kidney transplantation; living donor; longitudinal study; major adverse cardiac event; major clinical study; male; multicenter study; never smoker; outcome assessment; prospective study; self report; smoking habit; adverse event; clinical trial; graft rejection; living donor; smoking | English | 2021 | 2021-12 | 10.1111/tri.14137 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Measurement of Family Management in Families of Individuals With Down Syndrome: A Cross-Cultural Investigation | Down syndrome (DS) is the most common genetic cause of intellectual disability worldwide. The purpose of this analysis was to determine the internal consistency reliability of eight language versions of the Family Management Measure (FaMM) and compare family management of DS across cultures. A total of 2,740 parents of individuals with DS from 11 countries completed the FaMM. The analysis provided evidence of internal consistency reliability exceeding .70 for four of six FaMM scales for the entire sample. Across countries, there was a pattern of positive family management. Cross-cultural comparisons revealed parents from Brazil, Spain, and the United States had the most positive family management and respondents from Ireland, Italy, Japan, and Korea had the least positive. The rankings were mixed for the four remaining countries. These findings provide evidence of overall strong internal consistency reliability of the FaMM. More cross-cultural research is needed to understand how social determinants of health influence family management in families of individuals with DS. | Van Riper, Marcia; Knafl, George J.; Barbieri-Figueiredo, Maria do Ceu; Caples, Maria; Choi, Hyunkyung; de Graaf, Gert; Duarte, Elysangela Dittz; Honda, Junko; Marta, Elena; Phetrasuwan, Supapak; Alfieri, Sara; Angelo, Margareth; Deoisres, Wannee; Fleming, Louise; dos Santos, Aline Soares; Rocha da Silva, Maria Joao; Skelton, Beth; van der Veek, Shelley; Knafl, Kathleen A. | Univ N Carolina, Sch Nursing, Carrington Hall,Room 433,Campus Box 7460, Chapel Hill, NC 27599 USA; Univ N Carolina, Chapel Hill, NC 27515 USA; Univ Porto, Ctr Hlth Technol & Serv Res, Porto, Portugal; Univ Coll Cork, Sch Nursing & Midwifery, Cork, Ireland; Kyungpook Natl Univ, Coll Nursing, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Nursing Sci, Daegu, South Korea; Dutch Down Syndrome Fdn, Meppel, Netherlands; Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil; Univ Hyogo, Coll Art & Sci, Akashi, Hyogo, Japan; Univ Cattolica Sacro Cuore, Social & Community Psychol, Psychol Dept, Milan, Italy; Univ Cattolica Sacro Cuore, Milan, Italy; Mahidol Univ, Nursing, Bangkoknoi, Thailand; Univ Sao Paulo, Grp Studies Family Nursing, Sch Nursing, Sao Paulo, Brazil; Rambhai Barni Rajabhat Univ, Fac Nursing, Muang, Thailand; Garden Valley Sch Div, Winkler, MB, Canada; Univ Porto, Nursing Sci, Porto, Portugal; Leiden Univ, Leiden, Netherlands | Barbieri-Figueiredo, MC/F-4264-2015; Choi, Hyunkyung/AAB-4461-2022; caples, maria/ABD-4409-2021; Duarte, Elysangela/F-3593-2015; Fleming, Louise/ABD-7452-2020; Alfieri, Sara/N-9315-2014; Angelo, Margareth/Q-7696-2016; Honda, Junko/G-8619-2017; Barbieri-Figueiredo, Maria do Céu/F-4264-2015; Van Riper, Marcia/AAH-5409-2020 | 6603600339; 6602234418; 55044697100; 36959441200; 55619940700; 37039311600; 24166544300; 57215531353; 58153827500; 8702252700; 54893001900; 7006683597; 56216061000; 54418677900; 57220180359; 57220190527; 57220188403; 15837961300; 7004357667 | vanriper@email.unc.edu; | JOURNAL OF FAMILY NURSING | J FAM NURS | 1074-8407 | 1552-549X | 27 | 1 | SSCI;SCIE | FAMILY STUDIES;NURSING | 2021 | 2.68 | 21.5 | 1.51 | 2025-07-30 | 11 | 10 | family; Down syndrome; family management; measurement; quantitative; cross-cultural | QUALITY-OF-LIFE; CHILDHOOD CHRONIC CONDITIONS; AUTISM SPECTRUM DISORDERS; YOUNG-PEOPLE; INTELLECTUAL DISABILITY; MATERNAL PERCEPTIONS; SYNDROME ADVANTAGE; CHINESE CHILDREN; MOTHERS; ADAPTATION | cross-cultural; Down syndrome; family; family management; measurement; quantitative | Cross-Cultural Comparison; Down Syndrome; Humans; Parents; Reproducibility of Results; Surveys and Questionnaires; United States; child parent relation; cultural factor; Down syndrome; human; questionnaire; reproducibility; United States | English | 2021 | 2021-02 | 10.1177/1074840720975167 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Analysis of Heat and Mass Distribution in a Single- and Multi-Span Greenhouse Microclimate | Recently, heat and mass distributions within a greenhouse were assumed to be homogeneous. Heat is gained or lost in absolute terms, and crop contribution in a greenhouse or its effect is not considered. In this study, statistical analyses were conducted to establish the significance of heat and mass variation at sensor nodes in two single-span and multi-span greenhouses. Three greenhouses were used in this study, 168 m(2) floor area a single-layered (SLG), double-layered (DLG) single-span gothic roof type greenhouses, and 7572.6 m(2) floor area multi-span greenhouse (MSG). The microclimatic parameters investigated were temperature (T), relative humidity (RH), solar radiation (SR), carbon dioxide (CO2), and vapor pressure deficit (VPD). To check their horizontal distribution, all microclimate data collected from each sensor node in each greenhouse were subjected to descriptive statistics and Tukey honestly significant difference (HSD) test. The lowest minimum temperatures of 2.93 degrees C, 3.33 degrees C and 10.50 degrees C were recorded at sensor points in SLG, DLG, and MSG, respectively, whereas the highest maximum temperatures of 29.17 degrees C, 29.07 degrees C and 27.20 degrees C were recorded at sensor point, in SLG, DLG, and MSG, respectively. The difference between the center and the side into the single-span was approximately 0.88-1.0 degrees C and in the MSG was approximately 1.03 degrees C. Significant variation was observed in the horizontal distribution of T, RH, SR, and VPD within SLG, DLG, and MSG. Also significant was CO2 in the MSG. Estimating the energy demand of greenhouses should be done based on the distribution rather than assuming microclimatic parameters homogeneity, especially for T, with VPD as a control parameter. Such estimation should also be done using a crop model that considers instant changes in air and crop temperature. | Ogunlowo, Qazeem Opeyemi; Akpenpuun, Timothy Denen; Na, Wook-Ho; Rabiu, Anis; Adesanya, Misbaudeen Aderemi; Addae, Kwame Sasu; Kim, Hyeon-Tae; Lee, Hyun-Woo | Kyungpook Natl Univ, Coll Agr & Life Sci, Dept Agr Civil Engn, Daegu 702701, South Korea; Fed Coll Agr Ibadan, Dept Agr & Bioenvironm Engn, Ibadan 5029, Nigeria; Kyungpook Natl Univ, Smart Agr Innovat Ctr, Daegu 41566, South Korea; Univ Ilorin, Dept Agr & Biosyst Engn, Ilorin 1515, Nigeria; Gyeongsang Natl Univ, Dept Bioind Machinery Engn, Jinju 52828, South Korea | OGUNLOWO, QAZEEM/ABB-5386-2021; Akpenpuun, Timothy/AAE-1168-2020; Adesanya, Misbaudeen/AAA-4664-2022; RABIU, Anis/JXO-1947-2024 | 57265471800; 57194448083; 57211208368; 57264527100; 57264527200; 57264347700; 8662923200; 57209160180 | ogunlowoqazeem@knu.ac.kr;akpenpuun.td@unilorin.edu.ng;wooks121@knu.ac.kr;rabiuanis@knu.ac.kr;misbauadesanya@knu.ac.kr;kwameaddae@knu.ac.kr;bioani@gnu.ac.kr;whlee@knu.ac.kr; | AGRICULTURE-BASEL | AGRICULTURE-BASEL | 2077-0472 | 11 | 9 | SCIE | AGRONOMY | 2021 | 3.408 | 21.7 | 1.24 | 2025-07-30 | 13 | 15 | energy estimation; heat; mass; distribution; greenhouse; microclimate | TEMPERATURE DISTRIBUTION; VERTICAL TEMPERATURE; HUMIDITY; PATTERNS | Distribution; Energy estimation; Greenhouse; Heat; Mass; Microclimate | English | 2021 | 2021-09 | 10.3390/agriculture11090891 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Biocontrol Potential of Bacillus amyloliquefaciens against Botrytis pelargonii and Alternaria alternata on Capsicum annuum | The aim of this study was to assess the ability of Bacillus amyloliquefaciens, to augment plant growth and suppress gray mold and leaf spot in pepper plants. Morphological modifications in fungal pathogen hyphae that expanded toward the PGPR colonies were detected via scanning electron microscope. Furthermore, preliminary screening showed that PGPR could produce various hydrolytic enzymes in its media. Treatments with B. amyloliquefaciens suppressed Botrytis gray mold and Alternaria leaf spot diseases on pepper caused by Botrytis pelargonii and Alternaria alternata, respectively. The PGPR strain modulated plant physio-biochemical processes. The inoculation of pepper with PGPR decreased protein, amino acid, antioxidant, hydrogen peroxide, lipid peroxidation, and abscisic acid levels but increased salicylic acid and sugar levels compared to those of uninoculated plants, indicating a mitigation of the adverse effects of biotic stress. Moreover, gene expression studies confirmed physio-biochemical findings. PGPR inoculation led to increased expression of the CaXTH genes and decreased expression of CaAMP1, CaPR1, CaDEF1, CaWRKY2, CaBI-1, CaASRF1, CaSBP11, and CaBiP genes. Considering its beneficial effects, the inoculation of B. amyloliquefaciens can be proposed as an eco-friendly alternative to synthetic chemical fungicides. | Kazerooni, Elham Ahmed; Maharachchikumbura, Sajeewa S. N.; Al-Sadi, Abdullah Mohammed; Kang, Sang-Mo; Yun, Byung-Wook; Lee, In-Jung | Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Univ Elect Sci & Technol China, Sch Life Sci & Technol, Chengdu 611731, Peoples R China; Sultan Qaboos Univ, Coll Agr & Marine Sci, Dept Plant Sci, Al Khoud 123, Oman | ; maharachchikumbura, sajeewa/C-9403-2013; Kang, Sang-Mo/MBG-7823-2025; Al-Sadi, Abdullah/D-6766-2012; Maharachchikumbura, Sajeewa/C-9403-2013; Lee, In-Jung/GLS-0432-2022 | 57191375873; 54385665100; 8602920100; 56189696900; 8245123600; 16425830900 | elham.ghasemi.k@gmail.com;sajeewa83@yahoo.com;alsadi@squ.edu.om;rhizobacteria@gmail.com;bwyun@knu.ac.kr;ijlee@knu.ac.kr; | JOURNAL OF FUNGI | J FUNGI | 2309-608X | 7 | 6 | SCIE | MICROBIOLOGY;MYCOLOGY | 2021 | 5.724 | 21.7 | 2.74 | 2025-07-30 | 38 | 41 | plant growth promoting rhizobacteria; antagonism; disease suppression; pepper; hydrolytic enzymes | GROWTH-PROMOTING RHIZOBACTERIA; WRKY TRANSCRIPTION FACTORS; PLANT DEFENSE; 1ST REPORT; GRAY MOLD; ENDOPLASMIC-RETICULUM; GENE SUPERFAMILY; BAX INHIBITOR-1; SALICYLIC-ACID; GREY MOLD | Antagonism; Disease suppression; Hy-drolytic enzymes; Pepper; Plant growth promoting rhizobacteria | English | 2021 | 2021-06 | 10.3390/jof7060472 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Corneal Suturing Robot Capable of Producing Sutures With Desired Shape for Corneal Transplantation Surgery | In corneal transplantation, 16 submillimeter-sized sutures are generated around the circular-shaped graft cornea. A major challenge in corneal transplantation is the generation of uniformly shaped sutures, where the suture shapes need to be changed depending on the patient. In this study, a corneal suturing robot that can produce sutures of the desired shape with high uniformity is described. The proposed robot manipulates the corneal tissue deformation before inserting the needle for suture shape control. A simulation using the finite element method was proposed to predict the suture shape. The suturing experiment was conducted on a porcine model, and the result was compared with the simulation. As a result, the proposed robot was able to generate sutures with a standard deviation of 108 mu m in length and 36 mu m in depth. The mean absolute error between the simulation and the experiment was 95 mu m in length and 31 mu m in depth. This is the first study to suggest a method for controlling the suture shape and quantitatively analyzing it in ophthalmic surgery. | Shin, Hyung Gon; Park, Ikjong; Kim, Keehoon; Kim, Hong Kyun; Chung, Wan Kyun | Pohang Univ Sci & Technol, Dept Mech Engn, Pohang 37673, South Korea; Kyungpook Natl Univ, Sch Med, Dept Ophthlamol, Daegu 41944, South Korea; Yonsei Univ, Inst Convergence Res & Educ Adv Technol, Seoul 03722, South Korea | Kim, Hong Kyun/ITT-7758-2023 | 57220962897; 57192195676; 59475350100; 57218260940; 57204958534 | ko.h.g.shin@gmail.com;too1213@postech.ac.kr;khk@postech.ac.kr;okeye@knu.ac.kr; | IEEE TRANSACTIONS ON ROBOTICS | IEEE T ROBOT | 1552-3098 | 1941-0468 | 37 | 1 | SCIE | ROBOTICS | 2021 | 6.835 | 21.7 | 0.66 | 2025-07-30 | 12 | 13 | Finite element methods (FEM); medical robots and systems; simulation and animation; soft robot applications | Finite element methods (FEM); medical robots and systems; simulation and animation; soft robot applications | Agricultural robots; Grafts; Robotic surgery; Robots; Transplantation (surgical); Corneal tissues; Corneal transplantation; High uniformity; Mean absolute error; Ophthalmic surgery; Porcine models; Standard deviation; Submillimeters; Surgical equipment | English | 2021 | 2021-02 | 10.1109/tro.2020.3031885 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Effect of Planting Distance on the Mechanical Harvesting of Hot Pepper | Hot peppers are well known for being spicy and also have a high nutrient content. Human resources have formerly been used to harvest hot peppers; however, a high level of musculoskeletal risk to the human workforce has been reported. Therefore, to reduce the risk to farmers and replace the human workforce, the mechanical harvesting of hot pepper and steps to improve the harvesting efficiency of farmers were conducted. To achieve this, the effect of planting distance on the mechanical harvesting of hot peppers was analyzed at three planting distances (30, 40, and 50 cm) with several cultivars. Subsequently, machine-harvested hot peppers were classified into five groups (marketable, damaged, lost, unharvested, and twigged hot pepper), depending on their postharvest status. The average weight ratio of each group was then calculated, after which statistical analyses were conducted. The effect of planting distance on mechanical harvesting was then analyzed by comparing the differences between each group's average weight ratio and the total weight of hot pepper, which was simultaneously harvested mechanically at each planting distance. Results showed that the average weight ratio of marketable, unharvested, and twigged hot pepper improved as the planting distance increased. However, no effect on the average weight ratio of damaged and lost hot pepper was observed. The highest yield of marketable hot pepper was found at a planting distance of 40 cm, and the average weight ratio to the whole was lower than at 50 cm of planting distance. Thus, the most suitable planting distance for mechanical harvesting was 40 cm. | Kang, Seokho; Kim, Yeongsu; Park, Hyunggyu; Woo, Seungmin; Uyeh, Daniel Dooyum; Ha, Yushin | Kyungpook Natl Univ, Coll Agr & Life Sci, Dept Bioind Machinery Engn, Daehak Ro 80, Daegu 41566, South Korea | 57221791368; 57210594021; 57279183700; 57192074884; 57194449611; 57192072314 | deshshk@knu.ac.kr;mvio9256@knu.ac.kr;pyd4796@knu.ac.kr;kooger7571@naver.com;Uyehdooyum@knu.ac.kr;yushin72@knu.ac.kr; | AGRICULTURE-BASEL | AGRICULTURE-BASEL | 2077-0472 | 11 | 10 | SCIE | AGRONOMY | 2021 | 3.408 | 21.7 | 0.09 | 2025-07-30 | 2 | 3 | Capsicum annuum L.; hot pepper harvester; machinery harvest efficiency; planting distance | JALAPENO PEPPER; YIELD; GROWTH; DENSITY; FRUITS; L. | Capsicum annuum L; Hot pepper harvester; Machinery harvest efficiency; Planting distance | English | 2021 | 2021-10 | 10.3390/agriculture11100945 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | High-Resolution 3D Crop Reconstruction and Automatic Analysis of Phenotyping Index Using Machine Learning | Beyond the use of 2D images, the analysis of 3D images is also necessary for analyzing the phenomics of crop plants. In this study, we configured a system and implemented an algorithm for the 3D image reconstruction of red pepper plant (Capsicum annuum L.), as well as its automatic analysis. A Kinect v2 with a depth sensor and a high-resolution RGB camera were used to obtain more accurate reconstructed 3D images. The reconstructed 3D images were compared with conventional reconstructed images, and the data of the reconstructed images were analyzed with respect to their directly measured features and accuracy, such as leaf number, width, and plant height. Several algorithms for image extraction and segmentation were applied for automatic analysis. The results showed that the proposed method showed an error of about 5 mm or less when reconstructing and analyzing 3D images, and was suitable for phenotypic analysis. The images and analysis algorithms obtained by the 3D reconstruction method are expected to be applied to various image processing studies. | Yang, Myongkyoon; Cho, Seong-In | Seoul Natl Univ, Dept Biosyst Engn & Biomat Sci, Seoul 08826, South Korea; Kyungpook Natl Univ, Smart Agr Innovat Ctr, Daegu 41566, South Korea | 57194176323; 24499009200 | yangmk@knu.ac.kr; | AGRICULTURE-BASEL | AGRICULTURE-BASEL | 2077-0472 | 11 | 10 | SCIE | AGRONOMY | 2021 | 3.408 | 21.7 | 0.71 | 2025-07-30 | 12 | 13 | 3D reconstruction; phenotyping; machine learning; red pepper | CAMERA; CALIBRATION; ACCURACY; KINECT; SYSTEM | 3D reconstruction; Machine learning; Phenotyping; Red pepper | English | 2021 | 2021-10 | 10.3390/agriculture11101010 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | L-Lactic Acid Production Using Engineered Saccharomyces cerevisiae with Improved Organic Acid Tolerance | Lactic acid is mainly used to produce bio-based, bio-degradable polylactic acid. For industrial production of lactic acid, engineered Saccharomyces cerevisiae can be used. To avoid cellular toxicity caused by lactic acid accumulation, pH-neutralizing agents are used, leading to increased production costs. In this study, lactic acid-producing S. cerevisiae BK01 was developed with improved lactic acid tolerance through adaptive laboratory evolution (ALE) on 8% lactic acid. The genetic basis of BK01 could not be determined, suggesting complex mechanisms associated with lactic acid tolerance. However, BK01 had distinctive metabolomic traits clearly separated from the parental strain, and lactic acid production was improved by 17% (from 102 g/L to 119 g/L). To the best of our knowledge, this is the highest lactic acid titer produced by engineered S. cerevisiae without the use of pH neutralizers. Moreover, cellulosic lactic acid production by BK01 was demonstrated using acetate-rich buckwheat husk hydrolysates. Particularly, BK01 revealed improved tolerance against acetic acid of the hydrolysates, a major fermentation inhibitor of lignocellulosic biomass. In short, ALE with a high concentration of lactic acid improved lactic acid production as well as acetic acid tolerance of BK01, suggesting a potential for economically viable cellulosic lactic acid production. | Jang, Byeong-Kwan; Ju, Yebin; Jeong, Deokyeol; Jung, Sung-Keun; Kim, Chang-Kil; Chung, Yong-Suk; Kim, Soo-Rin | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Major Food Applicat Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Hort, Daegu 41566, South Korea; Jeju Natl Univ, Dept Plant Resources & Environm, Jeju 63243, South Korea | Jeong, Deokyeol/GLR-8021-2022; Jang, Byeong Kwan/IQV-9121-2023; Kim, Soo Rin/X-2192-2019; Chung, Yong/V-6909-2019; Jung, SUNG KEUN/AGR-2623-2022 | 57220054462; 57221630545; 57191332457; 35310491400; 7409880701; 36983850100; 36659584200 | byeonggwan_jang@naver.com;jyb52795279@gmail.com;dyj@knu.ac.kr;skjung04@knu.ac.kr;ckkim@knu.ac.kr;yschung@jejunu.ac.kr;soorinkim@knu.ac.kr; | JOURNAL OF FUNGI | J FUNGI | 2309-608X | 7 | 11 | SCIE | MICROBIOLOGY;MYCOLOGY | 2021 | 5.724 | 21.7 | 2.19 | 2025-07-30 | 29 | 29 | lactate dehydrogenase; whole-genome sequencing; Saccharomyces cerevisiae; lignocellulosic biomass; polylactic acid | MICROBIAL-PRODUCTION; METABOLOME; XYLOSE; FERMENTATION; OPTIMIZATION | Lactate dehydrogenase; Lignocellu-losic biomass; Polylactic acid; Saccharomyces cerevisiae; Whole-genome sequencing | English | 2021 | 2021-11 | 10.3390/jof7110928 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Modification of Oxidized Starch Polymer with Nanoclay for Enhanced Adhesion and Free Formaldehyde Emission of Plywood | This study is aiming of developing eco-friendly wood adhesive based on oxidized starch (OS) modified by nanoclay to enhance their adhesion and no formaldehyde emission. Two types of nanoclay such as pristine-bentonite (P-BNT) and transition metal ion modified-pristine-bentonite (TMI-P-BNT) at three levels (i.e., 1, 3, and 5%) were used for the modification of OS adhesive. Basic properties, chemical properties and thermal properties of the modified OS adhesives were examined with various analysis techniques to understand the influence of nanoclay modification on OS polymer. As the nanoclay level increased, the modified OS adhesives had greater solids content and viscosity but the gelation time decreased, indicating a faster curing of the modified OS adhesive. X-Ray diffraction of the modified OS adhesives resulted in a decrease in the 2 theta value and enlarged d-spacing value, showing that the nanoclay had been intercalated within OS polymer molecules. Two peaks at 526 cm(-1) and 461 cm(-1) detected by FTIR were assigned to Si-O-Al and Si-O-Si vibrations, respectively, and confirmed the presence of nanoclay in the OS polymer. Thermogravimetric analysis showed that the added nanoclay improved thermal stability of OS adhesives. The modified OS adhesives with 5% TMI-P-BNT enhanced their adhesion strength from 0.9 to 1.25 MPa, and resulted in free formaldehyde emission (near to 0.01 mg/L) from plywood panel. These results indicated that the modification of OS adhesives with 5% TMI-P-BNT could be used as bio-based and environmentally friendly plywood adhesive with zero formaldehyde emission. | Lubis, Muhammad Adly Rahandi; Yadav, Sumit Manohar; Park, Byung-Dae | Indonesian Inst Sci, Res Ctr Biomat, Cibinong 16911, Indonesia; Kyungpook Natl Univ, Dept Wood & Paper Sci, Daegu 41566, South Korea | Park, Byung-Dae/ABB-1934-2020; Lubis, Muhammad/K-2440-2019; Yadav, Sumit/AAI-2108-2020 | 57192278476; 57191834292; 7402834820 | byungdae@knu.ac.kr; | JOURNAL OF POLYMERS AND THE ENVIRONMENT | J POLYM ENVIRON | 1566-2543 | 1572-8919 | 29 | 9 | SCIE | ENGINEERING, ENVIRONMENTAL;POLYMER SCIENCE | 2021 | 4.705 | 21.7 | 1.46 | 2025-07-30 | 20 | 26 | Oxidized starch; Intercalated nanoclay; Adhesion; Formaldehyde free; Wood adhesive | SURFACE MODIFICATION; HYDROGEN-PEROXIDE; RESIN ADHESIVES; NANOCOMPOSITES | Adhesion; Formaldehyde free; Intercalated nanoclay; Oxidized starch; Wood adhesive | Adhesion; Bentonite; Chemical Analysis; Formaldehyde; Gelation; Gravimetry; Silicon; Thermal Analysis; Adhesion; Bentonite; Chemical analysis; Chemical modification; Formaldehyde; Gelation; Metal ions; Nanocomposites; Plywood; Silicon; Starch; Thermodynamic stability; Thermogravimetric analysis; Transition metal compounds; Transition metals; Wood products; Analysis techniques; Enhanced adhesions; Formaldehyde emission; Free formaldehydes; Oxidized starch; Plywood panels; Solids content; Wood adhesives; adhesion; formaldehyde; nanomaterial; polymer; starch; thermodynamic property; wood; Adhesives | English | 2021 | 2021-09 | 10.1007/s10924-021-02101-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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