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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Enhancement of Birefringence in Reduced Graphene Oxide Doped Liquid Crystal | We investigated the effect of reduced graphene oxide (rGO) doping on the birefringence of 5CB liquid crystal (LC). The characteristics of the synthesized rGO and LC-rGO composite with different rGO concentrations were analyzed by atomic force microscopy, X-ray photoelectron spectroscopy, white light polarized microscopy, voltage-dependent transmission measurement, and differential scanning calorimetry. We found that doping LC with an appropriate concentration of rGO enhances the birefringence of the LC. This is mainly due to the improved anisotropy of polarizability, which stems from the high shape anisotropy of rGO. However, the aggregation of rGO reduces the birefringence by decreasing the anisotropy of polarizability as well as the order parameter. Our study shows the promising potential of LC-rGO for developing various electro-optic devices that offer improved electro-optic effects. | Kumar, Mareddi Bharath; Adeshina, Mohammad Awwal; Kang, Daekyung; Jee, Youngho; Kim, Taewan; Choi, Muhan; Park, Jonghoo | Kyungpook Natl Univ, Dept Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Cresin Co Ltd, Gyeongsangbuk Do 40040, South Korea; Jeonbuk Natl Univ, Dept Elect Engn, Jeonju 54896, South Korea; Jeonbuk Natl Univ, Smart Grid Res Ctr, Jeonju 54896, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | Mareddi, Bharathkumar/HSA-7535-2023 | 57190606826; 57216582237; 57211869035; 57216584129; 57199878285; 7402093793; 57196408322 | 1992mbkr@gmail.com;mohammadadeshina1@gmail.com;kyoung_528@naver.com;jyh@cresin.com;tw20027@gmail.com;mhchoi@ee.knu.ac.kr;jonghoopark@knu.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 5 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 0.68 | 2025-06-25 | 16 | 16 | reduced graphene oxide; liquid crystal; phase modulator; birefringence | ELECTROOPTIC PROPERTIES; PHASE MODULATOR; NANOPARTICLES; POLARIZATION; PERFORMANCE; DISPERSION; MONOLAYERS; EFFICIENCY; ALIGNMENT; THEORIE | Birefringence; Liquid crystal; Phase modulator; Reduced graphene oxide | English | 2020 | 2020-05 | 10.3390/nano10050842 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Graphene Templated DNA Arrays and Biotin-Streptavidin Sensitive Bio-Transistors Patterned by Dynamic Self-Assembly of Polymeric Films Confined within a Roll-on-Plate Geometry | Patterning of surfaces with a simple strategy provides insights into the functional interfaces by suitable modification of the surface by novel techniques. Especially, highly ordered structural topographies and chemical features from the wide range of interfaces have been considered as important characteristics to understand the complex relationship between the surface chemistries and biological systems. Here, we report a simple fabrication method to create patterned surfaces over large areas using evaporative self-assembly that is designed to produce a sacrificial template and lithographic etch masks of polymeric stripe patterns, ranging from micrometer to nanoscale. By facilitating a roll-on-plate geometry, the periodically patterned surface structures formed by repetitive slip-stick motions were thoroughly examined to be used for the deposition of the Au nanoparticles decorated graphene oxide (i.e., AuNPs, similar to 21 nm) and the formation of conductive graphene channels. The fluorescently labeled thiol-modified DNA was applied on the patterned arrays of graphene oxide (GO)/AuNPs, and biotin-streptavidin sensitive devices built with graphene-based transistors (GFETs, effective mobility of similar to 320 cm(2)V(-1)s(-1)) were demonstrated as examples of the platform for the next-generation biosensors with the high sensing response up to similar to 1 nM of target analyte (i.e., streptavidin). Our strategy suggests that the stripe patterned arrays of polymer films as sacrificial templates can be a simple route to creating highly sensitive biointerfaces and highlighting the development of new chemically patterned surfaces composed of graphene-based nanomaterials. | Jeon, Sangheon; Lee, Jihye; Park, Rowoon; Jeong, Jeonghwa; Shin, Min Chan; Eom, Seong Un; Park, Jinyoung; Hong, Suck Won | Pusan Natl Univ, Coll Nanosci & Nanotechnol, Dept Opt & Mechatron Engn, Dept Cognomechatron Engn, Busan 46241, South Korea; LG Innotek Co Ltd, Substrate & Mat Lab, Gumi 39419, South Korea; Kyungpook Natl Univ, Sch Appl Chem Engn, Daegu 41566, South Korea | PARK, JUN-YOUNG/P-5981-2015; Shin, Min/AAU-6206-2021 | 57202416639; 55689992200; 57202423243; 57197117040; 57218903537; 55909713500; 57286293400; 57252820400 | sangheon.jn@gmail.com;jihyelee970@gmail.com;rowoon.p153@gmail.com;2jeong.s.o@gmail.com;mch3024@gmail.com;sueom89@gmail.com;jinpark@knu.ac.kr;swhong@pusan.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 8 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 0.55 | 2025-06-25 | 10 | 11 | self-assembly; graphene; DNA; biosensor; field-effect transistor | OXIDE; GOLD; NANOMATERIALS; EVAPORATION; ELECTRODES; BIOSENSORS; PLATFORM; SENSORS; BINDING | Biosensor; DNA; Field-effect transistor; Graphene; Self-assembly | English | 2020 | 2020-08 | 10.3390/nano10081468 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Manganese and Graphene Included Titanium Dioxide Composite Nanowires: Fabrication, Characterization and Enhanced Photocatalytic Activities | We report the detailed microstructural, morphological, optical and photocatalytic studies of graphene (G) and manganese (Mn) co-doped titanium dioxide nanowires (TiO2(G-Mn) NWs) prepared through facile combined electrospinning-hydrothermal processes. The as-prepared samples were thoroughly characterized using X-ray diffraction (XRD), transmission electron microscopy, X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, and diffuse reflectance spectroscopy (DRS). XRD studies reveal the formation of mixed anatase-rutile phases or rutile phase depending on the dopant (Mn) precursor concentrations in the electrospinning dope and calcination temperature. The evaluation of lattice parameters revealed that the incorporation of Mn species and carbon atoms in to the lattice of anatase or rutile TiO2 could occur through substituting the sites of oxygen atoms. XPS results confirm the existence of Mn2+/Mn3+ within the TiO2 NW. Raman spectroscopy provides the evidence for structural modification because of the graphene inclusion in TiO2 NW. The optical band gap of G-Mn including TiO2 is much lower than pristine TiO2 as confirmed through UV-vis DRS. The photocatalytic activities were evaluated by nitric oxide (NOx) degradation tests under visible light irradiation. Superior catalytic activity was witnessed for rutile G-Mn-co-doped TiO2 NW over their anatase counterparts. The enhanced photocatalytic property was discussed based on the synergistic effects of doped G and Mn atoms and explained by plausible mechanisms. | Lee, Jun-Cheol; Gopalan, Anantha-Iyengar; Saianand, Gopalan; Lee, Kwang-Pill; Kim, Wha-Jung | Kyungpook Natl Univ, Daegyeong Reg Infrastruct Technol Dev Ctr, Daegu 41566, South Korea; Univ Newcastle, Fac Sci, Callaghan, NSW 2308, Australia | Gopalan, Saianand/J-6000-2019 | 55694062800; 57191999779; 38362265400; 8382891300; 57203533494 | uggenius@hanmail.net;algopal99@gmail.com;SaiAnand.Gopalan@newcastle.edu.au;kplee@knu.ac.kr;kimwj@knu.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 3 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 1.6 | 2025-06-25 | 31 | 29 | titanium dioxide nanowires; graphene and manganese inclusion; phase transformation; photocatalytic performance; synergistic effects | VISIBLE-LIGHT-RESPONSE; TIO2 NANOPARTICLES; RUTILE PHASE; SRTIO3 PHOTOCATALYSTS; CODOPED TIO2; DEGRADATION; ANATASE; OXIDE; TEMPERATURE; CARBON | Graphene and manganese inclusion; Phase transformation; Photocatalytic performance; Synergistic effects; Titanium dioxide nanowires | English | 2020 | 2020-03 | 10.3390/nano10030456 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Recent Progress in the Abatement of Hazardous Pollutants Using Photocatalytic TiO2-Based Building Materials | Titanium dioxide (TiO2) has been extensively investigated in interdisciplinary research (such as catalysis, energy, environment, health, etc.) owing to its attractive physico-chemical properties, abundant nature, chemical/environmental stability, low-cost manufacturing, low toxicity, etc. Over time, TiO2-incorporated building/construction materials have been utilized for mitigating potential problems related to the environment and human health issues. However, there are challenges with regards to photocatalytic efficiency improvements, lab to industrial scaling up, and commercial product production. Several innovative approaches/strategies have been evolved towards TiO2 modification with the focus of improving its photocatalytic efficiency. Taking these aspects into consideration, research has focused on the utilization of many of these advanced TiO2 materials towards the development of construction materials such as concrete, mortar, pavements, paints, etc. This topical review focuses explicitly on capturing and highlighting research advancements in the last five years (mainly) (2014-2019) on the utilization of various modified TiO2 materials for the development of practical photocatalytic building materials (PBM). We briefly summarize the prospective applications of TiO2-based building materials (cement, mortar, concretes, paints, coating, etc.) with relevance to the removal of outdoor/indoor NOx and volatile organic compounds, self-cleaning of the surfaces, etc. As a concluding remark, we outline the challenges and make recommendations for the future outlook of further investigations and developments in this prosperous area. | Gopalan, Anantha-Iyengar; Lee, Jun-Cheol; Saianand, Gopalan; Lee, Kwang-Pill; Sonar, Prashant; Dharmarajan, Rajarathnam; Hou, Yao-long; Ann, Ki-Yong; Kannan, Venkatramanan; Kim, Wha-Jung | Kyungpook Natl Univ, Daegyeong Reg Infrastruct Technol Dev Ctr, Daegu 41566, South Korea; Seowon Univ, Dept Architecture, Cheongju 28674, South Korea; Univ Newcastle, Fac Sci, Global Ctr Environm Remediat GCER, Callaghan, NSW 2308, Australia; Queensland Univ Technol, Sch Chem & Phys, 2 George St, Brisbane, Qld 4001, Australia; Queensland Univ Technol, Ctr Mat Sci, 2 George St, Brisbane, Qld 4001, Australia; Kyungpook Natl Univ, Dept Civil Engn, 80 Daehakro, Daegu 41566, South Korea; Hanyang Univ, Dept Civil & Environm Engn, Ansan 1588, South Korea; SCSVMV Deemed Univ, Dept Phys, Kanchipuram 631561, India | Hou, Yaolong/KRP-4300-2024; Dharmarajan, Raja/E-2781-2015; Gopalan, Saianand/J-6000-2019; kannan, venkatramanan/N-4628-2016; Sonar, Prashant/E-8827-2011; Dharmarajan, Rajarathnam/E-2781-2015 | 57191999779; 55694062800; 38362265400; 8382891300; 8523056200; 6507406276; 57210563078; 22978374800; 57218952492; 57203533494 | algopal99@gmail.com;uggenius@hanmail.net;SaiAnand.Gopalan@newcastle.edu.au;kplee@knu.ac.kr;Sonar.Prashant@qut.edu.au;Raja.Dharmarajan@newcastle.edu.au;hylmm8988@hotmail.com;kann@hanyang.ac.kr;kv@kanchiuniv.ac.in;kimwj@knu.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 9 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 0.9 | 2025-06-25 | 55 | 68 | building materials; photocatalytic; titanium dioxide; pollutant removal; self-cleaning | VOLATILE ORGANIC-COMPOUNDS; SELF-CLEANING PERFORMANCE; INDOOR AIR PURIFICATION; CEMENTITIOUS MATERIALS; MODIFIED TIO2; NITROGEN-OXIDES; NOX ABATEMENT; ANATASE TIO2; DOPED TIO2; COMPOSITE PHOTOCATALYSTS | Building materials; Photocatalytic; Pollutant removal; Self-cleaning; Titanium dioxide | English | 2020 | 2020-09 | 10.3390/nano10091854 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Self-Alignment of Bottom CZTSSe by Patterning of an Al2O3 Intermediate Layer | When CZTSSe is synthesized using a metal precursor, large voids of nonuniform size form at Mo back contact side. Herein, we demonstrate that the voids and CZTSSe in the lower part of the CZTSSe double layer can be controlled by using an Al2O3-patterned Mo substrate. The CZTSSe in the lower part self-aligns on the Mo-exposed area, while the voids self-align on the Al2O3-coated area. The origin of the self-alignment is expected to be the difference in bonding characteristics between liquid Sn and the metal or oxide surface, e.g., Al2O3. Good wettability generally forms between nonreactive liquid metals and metal surfaces due to the strong metallic bonding. By contrast, poor wettability generally forms between nonreactive liquid metals and oxide surfaces due to the weak van der Waals bonding between the liquid metal and the oxide layer. When the patterning was added, the device efficiency tended to decrease from 8.6% to 10.5%. | Hong, Sanghun; Kim, Se-Yun; Son, Dae-Ho; Kim, Seung-Hyun; Kim, Young-Ill; Yang, Kee-Jeong; Heo, Young-Woo; Kang, Jin-Kyu; Kim, Dae-Hwan | Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; DGIST, Res Ctr Thin Film Solar Cells, Daegu 42988, South Korea; DGIST, Div Energy Technol, Daegu 42988, South Korea | Kim, Seung/LWK-2647-2024; Jin-Kyu, Kang/AAR-9096-2021; Kim, Jihyun/F-6940-2013; Kim, Jonghwan/AAR-2815-2021 | 57209584605; 57191419632; 35786474400; 57190874876; 56066780100; 15763941100; 7004298542; 35096377300; 57778048600 | shhong@dgist.ac.kr;kimseyun@dgist.ac.kr;dhson@dgist.ac.kr;seunghyun@dgist.ac.kr;lynx012@dgist.ac.kr;kjyang@dgist.ac.kr;ywheo@knu.ac.kr;apollon@dgist.ac.kr;monolith@dgist.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 1 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 0.49 | 2025-06-25 | 9 | 9 | CZTSSe; intermediate layer; self-alignment; wettability; metal precursor; two-step | SOLAR-CELL | CZTSSe; Intermediate layer; Metal precursor; Self-alignment; Two-step; Wettability | English | 2020 | 2020-01 | 10.3390/nano10010043 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Self-Assembled Multi-Epitope Peptide Amphiphiles Enhance the Immune Response against Enterovirus 71 | Subunit vaccines consist of non-genetic material, such as peptides or proteins. They are considered safe because they have fewer side effects; however, they have low immunogenicity when used alone. We aimed to enhance the immune response of peptide-based vaccines by using self-assembled multimeric peptide amphiphiles (PAs). We designed two epitope PAs by conjugating epitope peptides from Enterovirus 71 (EV71) virus particle (VP) 1 and VP3 capsid proteins with different fatty acid chain lengths (VP1PA and VP3PA). These PAs self-assembled into supramolecular structures at a physiological pH, and the resulting structures were characterized using atomic force microscopy. Multi-epitope PAs (m-PAs) consisted of a 1:1 mixture of VP1PA and VP3PA solutions. To evaluate immunogenicity, m-PA constructs were injected with adjuvant subcutaneously into female Balb/c mice. Levels of antigen-specific immunoglobulin G (IgG) and IgG1 in m-PA-injected mice serum samples were analyzed using ELISA and Western blotting. Additionally, cytokine production stimulated by each antigen was measured in splenocytes cultured from immunized mice groups. We found that m-PA showed improved humoral and cellular immune responses compared to the control and peptide groups. The sera from m-PA immunized mice group could neutralize EV71 infection and protect host cells. Thus, self-assembled m-PAs can promote a protective immune response and can be developed as a potential platform technology to produce peptide vaccines against infectious viral diseases. | Kim, Yu-Gyeong; Lee, Yunsu; Kim, Joo Hee; Chang, Sun-Young; Jung, Jong-Wha; Chung, Woo-Jae; Jin, Hyo-Eon | Ajou Univ, Coll Pharm, Suwon 16499, South Korea; Kyungpook Natl Univ, Coll Pharm, Res Inst Pharmaceut Sci, Daegu 41566, South Korea; Sungkyunkwan Univ, Dept Integrat Biotechnol, Suwon 16419, South Korea; Ajou Univ, Res Inst Pharmaceut Sci & Technol, Suwon 16499, South Korea | kim, elise/AAB-7525-2022 | 57220069139; 57220073029; 57222724953; 55494237100; 26032128600; 36664394400; 55920163800 | yoog607@ajou.ac.kr;akbird1025@ajou.ac.kr;elisekim@ajou.ac.kr;sychang@ajou.ac.kr;jungj@knu.ac.kr;wjchung@skku.edu;hjin@ajou.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 12 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 0.25 | 2025-06-25 | 5 | 6 | peptide amphiphile; immune stimulator; vaccine; viral infectious disease; Enterovirus 71 | VIRUS-LIKE PARTICLES; VACCINE; PROTECTION; ADJUVANT; ANTIBODY; HISTORY; SIZE | Enterovirus 71; Immune stimulator; Peptide amphiphile; Vaccine; Viral infectious disease | English | 2020 | 2020-12 | 10.3390/nano10122342 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Simple Fabrication of Transparent, Colorless, and Self-Disinfecting Polyethylene Terephthalate Film via Cold Plasma Treatment | Cross-infection following cross-contamination is a serious social issue worldwide. Pathogens are normally spread by contact with germ-contaminated surfaces. Accordingly, antibacterial surface technologies are urgently needed and have consequently been actively developed in recent years. Among these technologies, biomimetic nanopatterned surfaces that physically kill adhering bacteria have attracted attraction as an effective technological solution to replace toxic chemical disinfectants (biocides). Herein, we introduce a transparent, colorless, and self-disinfecting polyethylene terephthalate (PET) film that mimics the surface structure of the Progomphus obscurus (sanddragon) wing physically killing the attached bacteria. The PET film was partially etched via a 4-min carbon tetrafluoride (CF4) plasma treatment. Compared to a flat bare PET film, the plasma-treated film surface exhibited a uniform array structure composed of nanopillars with a 30 nm diameter, 237 nm height, and 75 nm pitch. The plasma-treated PET film showed improvements in optical properties (transmittance and B*) and antibacterial effectiveness over the bare film; the transparency and colorlessness slightly increased, and the antibacterial activity increased from 53.8 to 100% for Staphylococcus aureus, and from 0 to 100% for Escherichia coli. These results demonstrated the feasibility of the CF4 plasma-treated PET film as a potential antibacterial overcoating with good optical properties. | Kim, Ji-Hyeon; Mun, ChaeWon; Ma, Junfei; Park, Sung-Gyu; Lee, Seunghun; Kim, Chang Su | Korea Inst Mat Sci, Adv Nanosurface Dept, Chang Won 51508, South Korea; Kyungpook Natl Univ, Sch Architectural Civil Environm & Energy Engn, Daegu 41566, South Korea | ; Lee, Seunghun/GYR-2414-2022; Park, Sung-Gyu/G-4466-2012 | 57210338058; 56046756500; 57207769424; 55154726900; 57203919907; 57201346735 | sangdu87@kims.re.kr;apple1025@kims.re.kr;ready@kims.re.kr;sgpark@kims.re.kr;seunghun@kims.re.kr;cskim1025@kims.re.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 5 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 0.62 | 2025-06-25 | 16 | 17 | polyethylene terephthalate; CF4 plasma treatment; dry etching; nanopillar structure; self-disinfecting | ANTIMICROBIAL SURFACES; ANTIBACTERIAL; STABILITY; COATINGS; TITANIUM | CF<sub>4</sub> plasma treatment; Dry etching; Nanopillar structure; Polyethylene terephthalate; Self-disinfecting | English | 2020 | 2020-05 | 10.3390/nano10050949 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Styrene-Based Elastomer Composites with Functionalized Graphene Oxide and Silica Nanofiber Fillers: Mechanical and Thermal Conductivity Properties | The mechanical and thermal conductivity properties of two composite elastomers were studied. Styrene-butadiene rubber (SBR) filled with functionalized graphene oxide (GO) and silica nanofibers, and styrene-butadiene-styrene (SBS) block copolymers filled with graphene oxide. For the SBR composites, GO fillers with two different surface functionalities were synthesized (cysteamine and dodecylamine) and dispersed in the SBR using mechanical and liquid mixing techniques. The hydrophilic cysteamine-based GO fillers were dispersed in the SBR by mechanical mixing, whereas the hydrophobic dodecylamine-based GO fillers were dispersed in the SBR by liquid mixing. Silica nanofibers (SnFs) were fabricated by electrospinning a sol-gel precursor solution. The surface chemistry of the functionalized fillers was studied in detail. The properties of the composites and the synergistic improvements between the GO and SnFs are presented. For the SBS composites, GO fillers were dispersed in the SBS elastomer at several weight percent loadings using liquid mixing. Characterization of the filler material and the composite elastomers was performed using x-ray photoelectron spectroscopy, x-ray diffraction, transmission electron microscopy, scanning electron microscopy, thermogravimetric analysis, dynamic mechanical analysis, tensile testing, nanoindentation, thermal conductivity and abrasion testing. | Park, Jaehyeung; Sharma, Jaswinder; Monaghan, Kyle W.; Meyer, Harry M., III; Cullen, David A.; Rossy, Andres M.; Keum, Jong K.; Wood, David L., III; Polizos, Georgios | Oak Ridge Natl Lab, Energy & Transportat Sci Div, Oak Ridge, TN 37831 USA; Kyungpook Natl Univ, Dept Biofibers & Mat Sci, Daegu 41566, South Korea; Oak Ridge Natl Lab, Mat Sci & Technol Div, Oak Ridge, TN 37831 USA; Oak Ridge Natl Lab, Ctr Nanophase Mat Sci, Oak Ridge, TN 37831 USA; Oak Ridge Natl Lab, Neutron Scattering Div, Oak Ridge, TN 37831 USA | ; Meyer, Harry/G-6949-2017; Keum, Jong/N-4412-2015; Wood, David/AAW-7459-2020; Cullen, David/A-2918-2015 | 55566554000; 57203232653; 57219110035; 35555450500; 24331224600; 57204267112; 26642999400; 48462221900; 6602247302 | parkj@knu.ac.kr;sharmajk@ornl.gov;kylewmonaghan@gmail.com;meyerhmiii@ornl.gov;cullenda@ornl.gov;marquezae@ornl.gov;keumjk@ornl.gov;wooddl@ornl.gov;polyzosg@ornl.gov; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 10 | 9 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2020 | 5.076 | 21.6 | 0.74 | 2025-06-25 | 15 | 17 | SBR composites; SBS composites; graphene oxide; silica nanofibers; mechanical properties; thermal conductivity | HYBRID COMPOSITES; CROSS-LINKING; CARBON-BLACK; NANOCOMPOSITES; NANOPARTICLES; MORPHOLOGY; REDUCTION; MEMBRANES; STRENGTH; COATINGS | Graphene oxide; Mechanical properties; SBR composites; SBS composites; Silica nanofibers; Thermal conductivity | English | 2020 | 2020-09 | 10.3390/nano10091682 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A Study of Cu Doping Effects in P2-Na0.75Mn0.6Fe0.2(CuxNi0.2-x)O2 Layered Cathodes for Sodium-Ion Batteries | Layered sodium metal oxide cathodes have much broader choice of transition metal elements than the Li counterparts. A reversible Cu2+/3+ redox couple has recently been introduced in such Na cathodes. To study the role of Cu, here P2-type layered Na0.75Mn0.6Fe0.2(CuxNi0.2-x)O-2 compounds have been designed, synthesized and investigated. It shows the high initial capacity of 206 mAh/g and good capacity retention. Reversible oxygen redox activity is observed in our experiments. Our DFT calculations suggest that Cu can stabilize the oxygen redox by modifying the electronic structure together with Fe at high voltages. In addition, the strong P ' 2 transition observed at low voltages is induced by Jahn-Teller active Cu2+ with two competing effects of enhanced Na ion diffusivity and reduced electronic conductivity. | Wang, Yichao; Kim, Sooran; Lu, Jingyu; Feng, Guangyuan; Li, Xin | Harvard Univ, John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA; Kyungpook Natl Univ, Dept Phys Educ, Daegu 41566, South Korea | Lu, Jingyu/JXL-5617-2024 | 57202648805; 55146733200; 57287310700; 57287659500; 57209057218 | lixin@seas.harvard.edu; | BATTERIES & SUPERCAPS | BATTERIES SUPERCAPS | 2566-6223 | 3 | 4 | SCIE | ELECTROCHEMISTRY;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2020 | 7.093 | 21.7 | 1.29 | 2025-06-25 | 30 | 32 | Cu doping; diffusion; Jahn-Teller distortion; sodium-ion battery; oxygen redox | TOTAL-ENERGY CALCULATIONS; HIGH-CAPACITY; ELECTROCHEMICAL PROPERTIES; P2-TYPE; OXIDE; PERFORMANCE; PHASE; NI; SUBSTITUTION; ELECTRODE | Cu doping; diffusion; Jahn-Teller distortion; oxygen redox; sodium-ion battery | Cathodes; Copper; Copper compounds; Diffusion; Electronic structure; Iron compounds; Jahn-Teller effect; Manganese compounds; Metal ions; Nickel compounds; Oxygen; Redox reactions; Sodium compounds; Sodium-ion batteries; Competing effects; Cu-doping; DFT calculation; Electronic conductivity; Good capacity retentions; Layered cathode; Metal oxide cathodes; Transition metal elements; Phosphorus compounds | English | 2020 | 2020-04 | 10.1002/batt.201900172 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | CT window trainable neural network for improving intracranial hemorrhage detection by combining multiple settings | Window settings to rescale and contrast stretch raw data from radiographic images such as Computed Tomography (CT), X-ray and Magnetic Resonance images is a crucial step as data pre-processing to examine abnormalities and diagnose diseases. We propose a distant-supervised method for determining automatically the best window settings by attaching a window estimator module (WEM) to a deep convolutional neural network (DCNN)-based lesion classifier and training them in conjunction. Aside from predicting a flexible window setting for each raw image, we statistically identify the top four window settings by calculating the mean and standard deviations for the entire dataset. Images are scaled on each of the top settings estimated by WEM and following lesion classifiers are subsequently trained. We study the effects of only using the flexible window, the single fixed window as either a known default window used by radiologists or an estimated mean value, and two different approaches to combine results from the top window settings to improve the detection of intracranial hemorrhage (ICH) from brain CT images. Experimental results showed that using the top four window settings identified from the window estimator module and combining the results had the best performance. | Karki, Manohar; Cho, Junghwan; Lee, Eunmi; Hahm, Myong-Hun; Yoon, Sang-Youl; Kim, Myungsoo; Ahn, Jae-Yun; Son, Jeongwoo; Park, Shin-Hyung; Kim, Ki-Hong; Park, Sinyoul | CAIDE Syst Inc, Lowell, MA USA; Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurosurg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Emergency Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Daegu Catholic Univ, Dept Neurosurg, Sch Med, Daegu, South Korea; Yeungnam Univ, Dept Emergency Med, Coll Med, Daegu, South Korea | ; Cho, Junghwan/AAK-4752-2020; Karki, Manohar/AAF-7065-2019; Ahn, Jae Yun/N-2652-2017; Park, Shinhyung/LNQ-6428-2024 | 56702840000; 57424663500; 59110473500; 56015548700; 57195615457; 57210943611; 56937505400; 57638226800; 57203275843; 57201886535; 56184913500 | mkarki@caidesystems.com;jcho@caidesystems.com;olive@caidesystems.com;hammh7@gmail.com;customplus@naver.com;aldtn85@naver.com;portnoy27@hanmail.net;invader87@naver.com;shinhyungpark@knu.ac.kr;gneuros@cu.ac.kr;dryuri@naver.com; | ARTIFICIAL INTELLIGENCE IN MEDICINE | ARTIF INTELL MED | 0933-3657 | 1873-2860 | 106 | SCIE | COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE;ENGINEERING, BIOMEDICAL;MEDICAL INFORMATICS | 2020 | 5.326 | 21.7 | 2.24 | 2025-06-25 | 33 | 36 | Cr window estimator; Lesion classification; Intracranial hemorrhage; Combination of multiple window settings; Convolutional neural network; End-to-end diagnostic radiology learning | ACUTE STROKE; TOMOGRAPHY | Combination of multiple window settings; Convolutional neural network; CT window estimator; End-to-end diagnostic radiology learning; Intracranial hemorrhage; Lesion classification | Humans; Intracranial Hemorrhages; Magnetic Resonance Imaging; Neural Networks, Computer; Tomography, X-Ray Computed; Convolutional neural networks; Data handling; Deep neural networks; Image enhancement; Magnetic resonance; Magnetic resonance imaging; X ray radiography; Data preprocessing; Diagnose disease; Flexible window; Intracranial hemorrhages; Mean and standard deviations; Radiographic images; Supervised methods; Window settings; Article; brain hemorrhage; computer assisted tomography; convolutional neural network; cross validation; diagnostic accuracy; feature extraction; human; ICD-10; machine learning; major clinical study; nuclear magnetic resonance imaging; prediction; priority journal; radiologist; retrospective study; window estimator module; X ray; brain hemorrhage; diagnostic imaging; x-ray computed tomography; Computerized tomography | English | 2020 | 2020-06 | 10.1016/j.artmed.2020.101850 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Fully waterproof two-axis galvanometer scanner for enhanced wide-field optics optical-resolution photoacoustic microscopy | A large field-of-view and fast scanning of photoacoustic microscopy (PAM) relatively have been difficult to obtain due to the water-drowned structure of the system for the transmission of ultrasonic signals. Researchers have widely studied the achievement of a waterproof scanner for dynamic biological applications with a high-resolution and high signal-to-noise ratio. This Letter reports a novel, to the best of our knowledge, waterproof galvanometer scanner-based PAM system with a successfully attainable 9.0 mm x 14.5 mm scan region, amplitude scan rate of 40 kHz, and spatial resolution of 4.9 mu m. The in vivo characterization of a mouse brain in intact-skull microvascular visualization demonstrated its capability in biomedical imaging and is anticipated to be an effective technique for various preclinical and clinical studies. (C) 2020 Optical Society of America | Lee, Jaeyul; Han, Sangyeob; Seong, Daewoon; Lee, Junsoo; Park, Sungjo; Wijesinghe, Ruchire Eranga; Jeon, Mansik; Kim, Jeehyun | Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Laser Applicat Ctr, Inst Adv Convergence Technol, Daegu 41061, South Korea; Kyungil Univ, Dept Biomed Engn, Gyongsan 38428, South Korea | Lee, Junsoo/IUO-9627-2023; Wijesinghe, Ruchire/K-3797-2016 | 57188689420; 57193695305; 57212512353; 57209986073; 7501826338; 56018152300; 24171094000; 7601373350 | msjeon@knu.ac.kr; | OPTICS LETTERS | OPT LETT | 0146-9592 | 1539-4794 | 45 | 4 | SCIE | OPTICS | 2020 | 3.776 | 21.7 | 1.91 | 2025-06-25 | 29 | 32 | MOUSE-BRAIN; ULTRASOUND; TOMOGRAPHY | Animals; Brain; Electric Conductivity; Mechanical Phenomena; Mice; Microscopy; Photoacoustic Techniques; Signal-To-Noise Ratio; Water; Medical imaging; Scanning; Signal to noise ratio; Ultrasonic applications; Waterproofing; water; Biological applications; Biomedical imaging; Galvanometer scanner; High signal-to-noise ratio; Large field of views; Optical resolution; Spatial resolution; Ultrasonic signals; animal; brain; devices; diagnostic imaging; electric conductivity; mechanics; microscopy; mouse; photoacoustics; signal noise ratio; Photoacoustic microscopy | English | 2020 | 2020-02-15 | 10.1364/ol.380032 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Sequence, structure and function-based classification of the broadly conserved FAH superfamily reveals two distinct fumarylpyruvate hydrolase subfamilies | Fumarylacetoacetate hydrolase (FAH) superfamily proteins are found ubiquitously in microbial pathways involved in the catabolism of aromatic substances. Although extensive bioinformatic data on these proteins have been acquired, confusion caused by problems with the annotation of these proteins hinders research into determining their physiological functions. Here we classify 606 FAH superfamily proteins using a maximum likelihood (ML) phylogenetic tree, comparative gene-neighbourhood patterns and in vitro enzyme assays. The FAH superfamily proteins used for the analyses are divided into five distinct subfamilies, and two of them, FPH-A and FPH-B, contain the majority of the proteins of undefined function. These subfamilies include clusters designated FPH-I and FPH-II, respectively, which include two distinct types of fumarylpyruvate hydrolase (FPH), an enzyme involved in the final step of the gentisate pathway. We determined the crystal structures of these FPH enzymes at 2.0 angstrom resolutions and investigate the substrate binding mode by which these types of enzymes can accommodate fumarylpyruvate as a substrate. Consequentially, we identify the molecular signatures of the two types of FPH enzymes among the broadly conserved FAH superfamily proteins. Our studies allowed us to predict the relationship of unknown FAH superfamily proteins using their sequence information. | Hong, Hwaseok; Seo, Hogyun; Park, Woojin; Kim, Kyung-Jin | Kyungpook Natl Univ, Struct & Mol Biol Lab, Sch Life Sci, KNU Creat BioRes Grp, Daegu 702701, South Korea; Kyungpook Natl Univ, KNU Inst Microorganisms, Daegu 702701, South Korea | ; Kim, Kyung-Jin/MVY-3405-2025 | 57208592877; 57189697998; 57211680374; 55510867400 | kkim@knu.ac.kr; | ENVIRONMENTAL MICROBIOLOGY | ENVIRON MICROBIOL | 1462-2912 | 1462-2920 | 22 | 1 | SCIE | MICROBIOLOGY | 2020 | 5.491 | 21.7 | 0.62 | 2025-06-25 | 10 | 10 | CONTAINING PROTEIN-1 FAHD1; CATABOLIC PATHWAY; GENTISATE PATHWAY; DEGRADATION PATHWAY; AROMATIC-COMPOUNDS; GENES; PURIFICATION; MECHANISM; BIODEGRADATION; MALEYLPYRUVATE | Amino Acid Sequence; Bacterial Proteins; Hydrolases; Phylogeny; bacterial protein; fumarylpyruvate hydrolase; hydrolase; amino acid sequence; chemistry; classification; genetics; metabolism; phylogeny | English | 2020 | 2020-01 | 10.1111/1462-2920.14844 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Structural insight into bi-functional malonyl-CoA reductase | The bi-functional malonyl-CoA reductase is a key enzyme of the 3-hydroxypropionate bi-cycle for bacterial CO2 fixation, catalysing the reduction of malonyl-CoA to malonate semialdehyde and further reduction to 3-hydroxypropionate. Here, we report the crystal structure and the full-length architecture of malonyl-CoA reductase from Porphyrobacter dokdonensis. The malonyl-CoA reductase monomer of 1230 amino acids consists of four tandemly arranged short-chain dehydrogenases/reductases, with two catalytic and two non-catalytic short-chain dehydrogenases/reductases, and forms a homodimer through paring contact of two malonyl-CoA reductase monomers. The complex structures with its cofactors and substrates revealed that the malonyl-CoA substrate site is formed by the cooperation of two short-chain dehydrogenases/reductases and one novel extra domain, while only one catalytic short-chain dehydrogenase/reductase contributes to the formation of the malonic semialdehyde-binding site. The phylogenetic and structural analyses also suggest that the bacterial bi-functional malonyl-CoA has a structural origin that is completely different from the archaeal mono-functional malonyl-CoA and malonic semialdehyde reductase, and thereby constitute an efficient enzyme. | Son, Hyeoncheol Francis; Kim, Sangwoo; Seo, Hogyun; Hong, Jiyeon; Lee, Donghoon; Jin, Kyeong Sik; Park, Sunghoon; Kim, Kyung-Jin | Kyungpook Natl Univ, Sch Life Sci, KNU Inst Microorganisms, KNU Creat BioRes Grp, Daegu, South Korea; Pohang Univ Sci & Technol, Pohang Accelerator Lab, Pohang, South Korea; Ulsan Natl Inst Sci & Technol, Sch Energy & Chem Engn, Ulsan, South Korea | ; Kim, Kyung-Jin/MVY-3405-2025 | 56015598000; 59237076700; 57189697998; 57205354591; 57207418964; 8407514600; 57203275835; 55510867400 | kkim@knu.ac.kr; | ENVIRONMENTAL MICROBIOLOGY | ENVIRON MICROBIOL | 1462-2912 | 1462-2920 | 22 | 2 | SCIE | MICROBIOLOGY | 2020 | 5.491 | 21.7 | 0.35 | 2025-06-25 | 12 | 12 | AUTOTROPHIC CARBON FIXATION; COENZYME-A REDUCTASE; 3-HYDROXYPROPIONATE CYCLE; CHLOROFLEXUS-AURANTIACUS; KEY ENZYME; PATHWAY; ACID; REPLACEMENT; TOXICITY | Alphaproteobacteria; Binding Sites; Lactic Acid; Malondialdehyde; Malonyl Coenzyme A; Oxidoreductases; Phylogeny; Protein Binding; Protein Conformation; hydracrylic acid; lactic acid; malonaldehyde; malonic semialdehyde; malonyl coenzyme A; malonyl-Coa reductase; oxidoreductase; protein binding; Alphaproteobacteria; binding site; enzymology; metabolism; phylogeny; physiology; protein conformation | English | 2020 | 2020-02 | 10.1111/1462-2920.14885 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Hybrid inhibitors of DNA and HDACs remarkably enhance cytotoxicity in leukaemia cells | Chlorambucil is a nitrogen mustard-based DNA alkylating drug, which is widely used as a front-line treatment of chronic lymphocytic leukaemia (CLL). Despite its widespread application and success for the initial treatment of leukaemia, a majority of patients eventually develop acquired resistance to chlorambucil. In this regard, we have designed and synthesised a novel hybrid molecule, chloram-HDi that simultaneously impairs DNA and HDAC enzymes. Chloram-HDi efficiently inhibits the proliferation of HL-60 and U937 leukaemia cells with GI(50) values of 1.24 mu M and 1.75 mu M, whereas chlorambucil exhibits GI(50) values of 21.1 mu M and 37.7 mu M against HL-60 and U937 leukaemia cells, respectively. The mechanism behind its remarkably enhanced cytotoxicity is that chloram-HDi not only causes a significant DNA damage of leukaemia cells but also downregulates DNA repair protein, Rad52, resulting in the escalation of its DNA-damaging effect. Furthermore, chloram-HDi inhibits HDAC enzymes to induce the acetylation of alpha-tubulin and histone H3. | Song, Yoojin; Park, Sun You; Wu, Zhexue; Liu, Kwang-Hyeon; Seo, Young Ho | Keimyung Univ, Coll Pharm, Daegu, South Korea; Kyungpook Natl Univ, Coll Pharm, BK21 Plus KNU Multiomics Based Creat Drug Res Tea, Daegu, South Korea; Kyungpook Natl Univ, Pharmaceut Sci Res Inst, Daegu, South Korea | 57202578927; 56115220100; 55523767300; 55768214700; 36956116000 | seoyho@kmu.ac.kr; | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | J ENZYM INHIB MED CH | 1475-6366 | 1475-6374 | 35 | 1 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL | 2020 | 5.051 | 21.8 | 0.63 | 2025-06-25 | 9 | 9 | DNA damage; histone deacetylases; cancer; leukaemia | HISTONE DEACETYLASE INHIBITORS; STRAND BREAK REPAIR; NITROGEN-MUSTARD; BIOLOGICAL EVALUATION; RATIONAL DESIGN; HYDROXAMIC ACID; DAMAGE; CANCER; ACTIVATION; RESISTANCE | cancer; DNA damage; histone deacetylases; leukaemia | Antineoplastic Agents; Cell Cycle Checkpoints; Cell Proliferation; Chlorambucil; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured; 4 (4 aminophenyl) n hydroxybutanamide; 4 [4 (diethylamino)phenyl] n hydroxybutanamide; 4 [4 (dipropylamino)phenyl] n hydroxybutanamide; 4 [4 [bis(2 chloroethyl)amino]phenyl] n hydroxybutanamide; alpha tubulin; beta actin; caspase 3; caspase 8; chlorambucil; cytochrome P450 1A2; cytochrome P450 2C19; cytochrome P450 2C9; cytochrome P450 2D6; cytochrome P450 3A; histone deacetylase; histone deacetylase 1; histone deacetylase 3; histone deacetylase 6; histone deacetylase 7; histone deacetylase inhibitor; histone H2AX; histone H3; methyl 4 (4 aminophenyl)butanoate; methyl 4 [4 (diethylamino)phenyl]butanoate; methyl 4 [4 (dipropylamino)phenyl]butanoate; Rad52 protein; unclassified drug; antineoplastic agent; chlorambucil; DNA; histone deacetylase; histone deacetylase inhibitor; A-549 cell line; A2780 cell line; antileukemic activity; antiproliferative activity; Article; catalysis; chronic lymphatic leukemia; comet assay; controlled study; cytotoxicity; DNA content; DNA damage; down regulation; drug efficacy; drug synthesis; enzyme inhibition; female; G2 phase cell cycle checkpoint; histone acetylation; HL-60 cell line; human; human cell; hydrogen bond; hydroxylation; IC50; in vitro study; M phase cell cycle checkpoint; MCF-7 cell line; MDA-MB-231 cell line; molecular docking; priority journal; protein acetylation; U-937 cell line; U266B1 cell line; Western blotting; cell cycle checkpoint; cell proliferation; chemical structure; chemistry; chronic lymphatic leukemia; dose response; drug design; drug effect; drug screening; metabolism; pathology; structure activity relation; synthesis; tumor cell culture | English | 2020 | 2020-01-01 | 10.1080/14756366.2020.1754812 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Hepatocellular Carcinoma Risk Steadily Persists over Time Despite Long-Term Antiviral Therapy for Hepatitis B:A Multicenter Study | Background: Long-term antiviral therapy (AVT) for chronic hepatitis B (CHB) reduces the risk of hepatocellular carcinoma (HCC). We assessed the temporal trends in the incidence of HCC over time during long-term AVT among Asian patients with CHB. Methods: Patients with CHB receiving entecavir/tenofovir (ETV/TDF) as a first-line antiviral were recruited from four academic hospitals in the Republic of Korea. We compared the incidence of HCC during and after the first 5 years of ETV/TDF treatment. Results: Among 3,156 patients, the median age was 49.6 years and males predominated (62.4%). During the follow-up, 9.0% developed HCC. The annual incidence of HCC per 100 person years during the first 5 years (n = 1,671) and after the first 5 years (n = 1,485) was statistically similar (1.93% vs. 2.27%, P = 0.347). When the study population was stratified according to HCC prediction model, that is, modified PAGE-B score, the annual incidence of HCC was 0.11% versus 0.39% in the low-risk group (= 13 points; all P > 0.05). A Poisson regression analysis indicated that the duration of AVT did not significantly affect the overall trend of the incidence of HCC (adjusted annual incidence rate ratio = 0.85; 95% confidence interval, 0.66-1.11; P = 0.232). Conclusions: Despite long-term AVT, the risk of HCC steadily persists over time among patients with CHB in the Republic of Korea, in whom HBV genotype C2 predominates. Impact: Careful HCC surveillance is still essential. | Kim, Seung Up; Seo, Yeon Seok; Lee, Han Ah; Kim, Mi Na; Lee, Eun Ju; Shin, Hye Jung; Lee, Yu Rim; Lee', Hye Won; Park, Jun Yong; Kim, Do Young; Ahn, Sang Hoon; Han, Kwang-Hyub; Um, Soon Ho; Tak, Won Young; Kweon, Young Oh; Kim, Beom Kyung; Park, Soo Young | Yonsei Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Yonsei Univ, Coll Med, Inst Gastroenterol, Seoul, South Korea; Severance Hosp, Yonsei Liver Ctr, Seoul, South Korea; Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Internal Med, Seongnam, South Korea; Yonsei Univ, Coll Med, Dept Biomed Syst Informat, Biostat Collaborat Unit, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea | Kim, Yoon/J-2746-2012; Lee, YuRim/ITU-1407-2023; Kim, Eun Young/JCE-3602-2023; KIM, JEONGSEON/AAA-4643-2022; SANG-HOON, AHN/AAV-2600-2020; Kim, Yoon/G-6633-2015; Ahn, Sang Hoon/AFM-2603-2022; Park, Jun/H-7127-2019; Kim, Sung-Won/J-5409-2012; Lee, Hye/D-9081-2016 | 54933821200; 35234912400; 57190980926; 57202910894; 59512296200; 57203549694; 57194094753; 57200110315; 47861376300; 56119929100; 7401989551; 7402963689; 7005044023; 7004074582; 7004694832; 35302925200; 57191674344 | beomkkim@yuhs.ac;psyoung0419@gmail.com; | CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION | CANCER EPIDEM BIOMAR | 1055-9965 | 1538-7755 | 29 | 4 | SCIE | ONCOLOGY;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 4.254 | 21.9 | 2.23 | 2025-06-25 | 29 | 30 | PRACTICE GUIDELINES MANAGEMENT; VIRUS-INFECTION; LIVER FIBROSIS; MARKERS | entecavir; tenofovir disoproxil; adult; antiviral therapy; Article; cancer risk; chronic hepatitis B; controlled study; digestive system disease assessment; female; follow up; high risk population; human; incidence; intermediate risk population; liver cell carcinoma; low risk population; major clinical study; male; middle aged; modified PAGE B score; priority journal; university hospital | English | 2020 | 2020-04 | 10.1158/1055-9965.epi-19-0614 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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