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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | FeS2-incorporated 3D PCL scaffold improves new bone formation and neovascularization in a rat calvarial defect model | Three-dimensional (3D) scaffolds composed of various biomaterials, including metals, ceramics, and synthetic polymers, have been widely used to regenerate bone defects. However, these materials possess clear downsides, which prevent bone regeneration. Therefore, composite scaffolds have been developed to compensate these disadvantages and achieve synergetic effects. In this study, a naturally occurring biomineral, FeS2, was incorporated in PCL scaffolds to enhance the mechanical properties, which would in turn influence the biological characteristics. The composite scaffolds consisting of different weight fractions of FeS2 were 3D printed and compared to pure PCL scaffold. The surface roughness (5.77-fold) and the compressive strength (3.38-fold) of the PCL scaffold was remarkably enhanced in a dose-dependent manner. The in vivo results showed that the group with PCL/ FeS2 scaffold implanted had increased neovascularization and bone formation (2.9-fold). These results demonstrated that the FeS2 incorporated PCL scaffold might be an effective bioimplant for bone tissue regeneration. | Kang, Donggu; Lee, Yoon Bum; Yang, Gi Hoon; Choi, Eunjeong; Nam, Yoonju; Lee, Jeong-Seok; Lee, KyoungHo; Kim, Kil Soo; Yeo, MyungGu; Yoon, Gil-Sang; An, SangHyun; Jeon, Hojun | Baobab Healthcare Inc, Res Inst Addit Mfg & Regenerat Med, Ansan 15588, Gyeonggi Do, South Korea; Daegu Gyeongbuk Med Innovat Fdn K MEDI Hub, Preclin Res Ctr, Daegu 41061, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Korea Inst Ind Technol KITECH, Molds & Dies Technol R&D Grp, Bucheon Si 14441, Gyeonggi Do, South Korea | Kim, Seung/N-5248-2019; Yeo, MyungGu/AAJ-3844-2021; Yang, Gi Hoon/AAX-9449-2021 | 57191167154; 57222355818; 56338767100; 57204876199; 57225111147; 57195407729; 57220105850; 35272034300; 57225831602; 7103257931; 57102583100; 26867777500 | ash4235@kmedihub.re.kr;hojun@baobabhcare.com; | INTERNATIONAL JOURNAL OF BIOPRINTING | INT J BIOPRINTING | 2424-7723 | 2424-8002 | 9 | 1 | SCIE | ENGINEERING, BIOMEDICAL;MATERIALS SCIENCE, BIOMATERIALS | 2023 | 6.8 | 13.4 | 0.89 | 2025-06-25 | 10 | 7 | FeS2; PCL; 3D printed; Mechanical properties; Bone formation | IN-VITRO; COMPOSITE SCAFFOLDS; TISSUE; DIFFERENTIATION; OSTEOGENESIS; CELLS; STEREOLITHOGRAPHY; RECONSTRUCTION; PROLIFERATION; ANGIOGENESIS | 3d printed; Bone formation; Fes2; Mechanical properties; Pcl | English | 2023 | 2023 | 10.18063/ijb.v9i1.636 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Incidence and prevalence of Spinal and bulbar muscular atrophy in South Korea: a nationwide population-based study | Spinal and bulbar muscular atrophy (SBMA), or Kennedy's disease, is a rare X-linked neuromuscular disorder predominantly affecting males and caused by a mutation in the androgen receptor gene. The epidemiology and comorbidities associated with SBMA in different ethnicities remain poorly understood. This study investigated the prevalence, incidence, and comorbidities associated with SBMA in the South Korean population using the Health Insurance Review and Assessment Service (HIRA) database. We retrospectively reviewed diagnosed cases of SBMA (G12.25 code of the Korean Classification of Diseases-7th edition) registered from January 1, 2016, to December 31, 2019, to calculate incidence and prevalence rates and concomitant comorbidities. Additionally, we surveyed SBMA patients (questionnaire group) visiting our clinic in 2022 to compare comorbidities with the HIRA data. The mean incidence rate of SBMA in the Korean population was 0.36/100,000 males from 2018 to 2019, while the prevalence rate was approximately 0.46/100,000 males from 2016 to 2019. The most common comorbidities identified in HIRA were gastritis and duodenitis (99.7%), gastroesophageal reflux (90.5%), hyperlipidemia (88.4%), and liver disorders (75.2%), which showed similar results in the questionnaire group. Additionally, gastric cancer was the most common type of cancer reported in SBMA in South Korea; although indeterminate, age-related factors may contribute to the development of cancer in these patients. Our findings provide valuable insights into the epidemiology and associated comorbidities of SBMA within the Korean population, which could inform clinical practice and future clinical research. | Park, Jin-Mo; Kang, Minsung; Park, Jin-Sung | Dongguk Univ, Coll Med, Gyeongju Hosp, Dept Neurol, Gyeongju, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Neurol, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurol, Hoguk Ro 807, Daegu, South Korea | 55569003000; 57719257600; 44061744500 | neurojspark@gmail.com; | JOURNAL OF NEUROLOGY | J NEUROL | 0340-5354 | 1432-1459 | 270 | 10 | SCIE | CLINICAL NEUROLOGY | 2023 | 4.8 | 13.4 | 0.38 | 2025-06-25 | 2 | 2 | Spinal and bulbar muscular atrophy; Epidemiology; Prevalence; South Korea; National health insurance service | KENNEDYS-DISEASE | Epidemiology; National health insurance service; Prevalence; South Korea; Spinal and bulbar muscular atrophy | Bulbo-Spinal Atrophy, X-Linked; Humans; Incidence; Male; Muscular Atrophy, Spinal; Prevalence; Receptors, Androgen; Republic of Korea; Retrospective Studies; androgen receptor; adult; Article; cancer patient; clinical practice; clinical research; comorbidity; controlled study; disease classification; duodenitis; female; gastritis; gastroesophageal reflux; health insurance; human; hyperlipidemia; incidence; Kennedy disease; liver disease; major clinical study; male; middle aged; national health insurance; prevalence; retrospective study; South Korea; stomach cancer; epidemiology; genetics; incidence; Kennedy disease; prevalence; South Korea; spinal muscular atrophy | English | 2023 | 2023-10 | 10.1007/s00415-023-11842-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | Myelin Oligodendrocyte Glycoprotein Associated Disorder presenting with longitudinally extensive transverse myelitis after BNT162b2-COVID-19 booster vaccination: a case report | Park, Jin Sung; Kang, Minsung | Kyungpook Natl Univ, Chilgok Hosp, Daegu, South Korea | MULTIPLE SCLEROSIS JOURNAL | MULT SCLER J | 1352-4585 | 1477-0970 | 29 | 7 | SCIE | CLINICAL NEUROLOGY;NEUROSCIENCES | 2023 | 4.8 | 13.4 | 0 | English | 2023 | 2023-06 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Article | Augmented reality-based surgical guidance for wrist arthroscopy with bone-shift compensation | Background and objectives: Intraoperative joint condition is different from preoperative CT/MR due to the motion applied during surgery, inducing an inaccurate approach to surgical targets. This study aims to provide real-time augmented reality (AR)-based surgical guidance for wrist arthroscopy based on a bone-shift model through an in vivo computed tomography (CT) study.Methods: To accurately visualize concealed wrist bones on the intra-articular arthroscopic image, we pro-pose a surgical guidance system with a novel bone-shift compensation method using noninvasive fiducial markers. First, to measure the effect of traction during surgery, two noninvasive fiducial markers were at-tached before surgery. In addition, two virtual link models connecting the wrist bones were implemented. When wrist traction occurs during the operation, the movement of the fiducial marker is measured, and bone-shift compensation is applied to move the virtual links in the direction of the traction. The pro-posed bone-shift compensation method was verified with the in vivo CT data of 10 participants. Finally, to introduce AR, camera calibration for the arthroscope parameters was performed, and a patient-specific template was used for registration between the patient and the wrist bone model. As a result, a vir-tual bone model with three-dimensional information could be accurately projected on a two-dimensional arthroscopic image plane.Results: The proposed method was possible to estimate the position of wrist bone in the traction state with an accuracy of 1.4 mm margin. After bone-shift compensation was applied, the target point error was reduced by 33.6% in lunate, 63.3% in capitate, 55.0% in scaphoid, and 74.8% in trapezoid than those in preoperative wrist CT. In addition, a phantom experiment was introduced simulating the real surgical environment. AR display allowed to expand the field of view (FOV) of the arthroscope and helped in visualizing the anatomical structures around the bones.Conclusions: This study demonstrated the successful handling of AR error caused by wrist traction using the proposed method. In addition, the method allowed accurate AR visualization of the concealed bones and expansion of the limited FOV of the arthroscope. The proposed bone-shift compensation can also be applied to other joints, such as the knees or shoulders, by representing their bone movements using corresponding virtual links. In addition, the movement of the joint skin during surgery can be measured using noninvasive fiducial markers in the same manner as that used for the wrist joint.(c) 2022 Elsevier B.V. All rights reserved. | Jeung, Deokgi; Jung, Kyunghwa; Lee, Hyun-Joo; Hong, Jaesung | DGIST, Dept Robot & Mechatron Engn, Daegu, South Korea; Korea Res Inst Stand & Sci, Daejeon, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthopaed Surg, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Orthopaed Surg, 130 Dongduk Ro, Daegu 41944, South Korea; DGIST, Dept Robot & Mechatron Engineer ing, 333 Techno Jungang Daero, Daegu 42988, South Korea | ; Jeung, Deokgi/KFA-7442-2024 | 58044843300; 57040348700; 58838750100; 55825553700 | lidmania@daum.net;jhong@dgist.ac.kr; | COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | COMPUT METH PROG BIO | 0169-2607 | 1872-7565 | 230 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;COMPUTER SCIENCE, THEORY & METHODS;ENGINEERING, BIOMEDICAL;MEDICAL INFORMATICS | 2023 | 4.9 | 13.5 | 0.68 | 2025-06-25 | 5 | 6 | Wrist arthroscopy; Augmented reality; Bone-shift compensation; In vivo computed tomography | HAND-EYE CALIBRATION; NAVIGATION SYSTEM; BRAIN-SHIFT; WIDE-ANGLE; REGISTRATION; MODEL; INSTABILITY; KINEMATICS; SURGERY; MOTION | Augmented reality; Bone-shift compensation; In vivo computed tomography; Wrist arthroscopy | Arthroscopy; Augmented Reality; Humans; Imaging, Three-Dimensional; Tomography, X-Ray Computed; Wrist; Wrist Joint; Bone; Computerized tomography; Endoscopy; Error compensation; Joints (anatomy); Surgery; Surgical equipment; Virtual reality; Arthroscopic images; Bone-shift compensation; Fiducial marker; In vivo computed tomography; In-vivo; Shift compensation; Surgical guidance; Virtual Link; Wrist arthroscopy; Wrist bones; anatomical concepts; Article; augmented reality; bone shift compensation; capitate bone; clinical article; computer assisted tomography; computer model; digital imaging and communications in medicine; female; human; image reconstruction; image registration; in vivo study; kinematics; lunate bone; male; musculoskeletal system parameters; non invasive procedure; preoperative period; radius; scaphoid bone; trapezoid bone; wrist; wrist arthroscopy; arthroscopy; diagnostic imaging; procedures; surgery; three-dimensional imaging; x-ray computed tomography; Augmented reality | English | 2023 | 2023-03 | 10.1016/j.cmpb.2022.107323 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Genetic characterization of avian polyomaviruses identified from psittacine birds in South Korea | Budgerigar fledgling disease (BFD) is a contagious disease caused by avian polyomavirus (APV) in psittacine birds and causes high mortality rates. Here, eight APV-positive cases were confirmed from dead parrots or parrot tissue samples by polymerase chain reaction (PCR). Full-length genome sequencing showed high nucleotide identity (98.84-100%) between the APV strains. Phylogenetic analysis revealed that two genogroups were cocirculating in South Korea. The nucleotide sequences of five strains, collected from different parrot species, were identical; however, pathological lesions were observed in only two parrots, both aged 2 months. Pathology included necrotic spots in the liver, subcutaneous haemorrhage, hepatomegaly, ascites, intranuclear inclusion bodies, hepatocyte karyomegaly, hepatic necrosis, and bile duct proliferation. This suggests that the pathogenicity of APV might be host age-dependent regardless of the host species. This study improves our understanding of APV pathogenicity and provides a more detailed genetic characterization of APV strains.RESEARCH HIGHLIGHTSEight APV strains were identified in South Korea from 2019 to 2021.By phylogenetic analysis, South Korean APV strains were classified into two clades. | Yun, Ye-Ji; Song, Hyesoon; Kwon, Yong-Kuk; Park, Choi-Kyu; Kim, Hye-Ryoung | Avian Dis Div, Anim & Plant Quarantine Agcy, Gimcheon, South Korea; Kyungpook Natl Univ, Coll Vet Med, Anim Dis Intervent Ctr, Daegu 41566, South Korea | Kim, HyeRyoung/KHV-3905-2024 | 59620531900; 57201093893; 55449326300; 24768064900; 23982368400 | dvmkim77@korea.kr; | AVIAN PATHOLOGY | AVIAN PATHOL | 0307-9457 | 1465-3338 | 52 | 6 | SCIE | VETERINARY SCIENCES | 2023 | 2.5 | 13.5 | 0 | 2025-06-25 | 0 | 0 | Budgerigar fledgling disease; avian polyomavirus; parrot; molecular characterization; phylogenetic analysis; South Korea | FEATHER DISEASE VIRUS; PROTEINS; REGION; BEAK | avian polyomavirus; Budgerigar fledgling disease; molecular characterization; parrot; phylogenetic analysis; South Korea | Amazona amazonica; animal tissue; Article; ascites; bile duct disease; Budgerigar fledgling disease; cell nucleus inclusion body; communicable disease; comparative study; controlled study; Eclectus parrot; genetic analysis; hepatocyte karyomegaly; hepatomegaly; histopathology; liver cell damage; liver necrosis; Myiopsitta monachus; nonhuman; nucleotide sequence; nucleotide sequence; parrot; pathogenicity; phylogeny; Pionites melanocephalus; Poicephlus senegalus; polymerase chain reaction; Polyomavirus; psittacine; Psittacus erithacus; South Korea; subcutaneous hemorrhage; virus infection; virus strain; whole genome sequencing | English | 2023 | 2023-11-02 | 10.1080/03079457.2023.2247347 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Orthognathic surgical planning using graph CNN with dual embedding module: External validations with multi-hospital datasets | Background and objective: Despite recent development of AI, prediction of the surgical movement in the maxilla and mandible by OGS might be more difficult than that of tooth movement by orthodontic treatment. To evaluate the prediction accuracy of the surgical movement using pairs of pre-(T0) and post-surgical (T1) lateral cephalograms (latceph) of orthognathic surgery (OGS) patients and dual embedding module-graph convolution neural network (DEM-GCNN) model.Methods: 599 pairs from 3 institutions were used as training, internal validation, and internal test sets and 201 pairs from other 6 institutions were used as external test set. DEM-GCNN model (IEM, learning the lat-ceph images; LTEM, learning the landmarks) was developed to predict the amount and direction of surgical movement of ANS and PNS in the maxilla and B-point and Md1crown in the mandible. The distance between T1 landmark coordinates actually moved by OGS (ground truth) and predicted by DEM-GCNN model and preexisted CNN-based Model-C (learning the lat-ceph images) was compared.Results: In both internal and external tests, DEM-GCNN did not exhibit significant difference from ground truth in all landmarks (ANS, PNS, B-point, Md1crown, all P > 0.05). When the accumulated successful detection rate for each landmark was compared, DEM-GCNN showed higher values than Model-C in both the internal and external tests. In violin plots exhibiting the error distribution of the prediction results, both internal and external tests showed that DEM-GCNN had significant performance improvement in PNS, ANS, B-point, Md1crown than Model-C. DEM-GCNN showed significantly lower prediction error values than Model-C (one-jaw surgery, B-point, Md1crown, all P < 0.005; two-jaw surgery, PNS, ANS, all P < 0.05; B point, Md1crown, all P < 0.005).Conclusion: We developed a robust OGS planning model with maximized generalizability despite diverse qualities of lat-cephs from 9 institutions. | Kim, In-Hwan; Kim, Jun-Sik; Jeong, Jiheon; Park, Jae-Woo; Park, Kanggil; Cho, Jin-Hyoung; Hong, Mihee; Kang, Kyung-Hwa; Kim, Minji; Kim, Su-Jung; Kim, Yoon-Ji; Sung, Sang-Jin; Kim, Young Ho; Lim, Sung-Hoon; Baek, Seung-Hak; Kim, Namkug | Univ Ulsan, Asan Med Inst Convergence Sci & Technol, Asan Med Ctr, Dept Biomed Engn,Coll Med, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Convergence Med, 88,Olymp Ro 43 Gil, Seoul 05505, South Korea; Chonnam Natl Univ, Sch Dent, Dept Orthodont, Gwangju, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Orthodont, Daegu, South Korea; Wonkwang Univ, Sch Dent, Dept Orthodont, Iksan Si, South Korea; Ewha Womans Univ, Coll Med, Dept Orthodont, Seoul, South Korea; Kyung Hee Univ, Sch Dent, Dept Orthodont, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Orthodont, Seoul, South Korea; Ajou Univ, Sch Med, Inst Oral Hlth Sci, Dept Orthodont, Suwon, Gyeonggi Do, South Korea; Chosun Univ, Coll Dent, Dept Orthodont, Gwangju, South Korea; Seoul Natl Univ, Dent Res Inst, Sch Dent, Dept Orthodont, Daehak Ro 101, Seoul 03080, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Radiol, Seoul, South Korea | kim, youngho/AAG-5029-2020; KIM, SUHWAN/GSE-0120-2022; Kim, Namkug/E-3843-2012; Kim, Jun/AAA-8565-2019; Baek, Seung-Hak/NOE-8444-2025; Sung, Sang Jin/KBQ-4217-2024 | 57222816092; 57837493800; 57843623300; 57206939484; 58686192400; 15764519700; 57190379016; 35285868600; 57201330607; 57039799500; 57221435554; 7202731963; 57207443980; 36793499100; 35090967400; 16550058300 | namkugkim@gmail.com; | COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | COMPUT METH PROG BIO | 0169-2607 | 1872-7565 | 242 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;COMPUTER SCIENCE, THEORY & METHODS;ENGINEERING, BIOMEDICAL;MEDICAL INFORMATICS | 2023 | 4.9 | 13.5 | 0.57 | 2025-06-25 | 5 | 5 | Cephalometry; Deep learning; Dual embedding module; Graph convolution neural network; Maxillofacial surgery; Multicenter study; Orthognathic surgery; Surgical prediction | NEURAL-NETWORK; ARTIFICIAL-INTELLIGENCE; SURGERY; DIAGNOSIS; ACCURACY; JAW | Cephalometry; Deep learning; Dual embedding module; Graph convolution neural network; Maxillofacial surgery; Multicenter study; Orthognathic surgery; Surgical prediction | Cephalometry; Humans; Mandible; Maxilla; Orthognathic Surgical Procedures; Convolution; Deep learning; Embeddings; Neural network models; Surgery; Cephalometry; Convolution neural network; Deep learning; Dual embedding module; Embeddings; Graph convolution neural network; Maxillofacial surgery; Multi-centre study; Orthognathic surgeries; Surgical prediction; article; controlled study; convolutional neural network; deep learning; embedding; human; learning; mandible; maxilla; maxillofacial surgery; orthognathic surgery; prediction error; cephalometry; diagnostic imaging; mandible; procedures; surgery; Forecasting | English | 2023 | 2023-12 | 10.1016/j.cmpb.2023.107853 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Pure uric acid stone prediction model using the variant coefficient of stone density measured by thresholding 3D segmentation-based methods: A multicenter study | Urinary stones are common urological diseases with increasing prevalence and incidence worldwide. Among the various types of stones, uric acid stones can be dissolved by oral chemolysis without any sur-gical procedure. Therefore, our study demonstrates that variant coefficient of stone density measured by thresholding a three-dimensional segmentation-based method from noncontrast computed tomography images can be used to identify pure uric acid stones from non-pure uric acid stones. This study provides a preoperative pure uric acid stone prediction model that could reduce invasive procedural treatments. The pure uric acid stone prediction model may offer optimized clinical decision-making for patients with urinary stones.Background and objectives: While most urinary stones are managed with interventional therapy, uric acid (UA) stones can be dissolved by oral chemolysis without invasive procedures. This study aimed to develop and validate a pure UA (pUA) stone prediction model using a variant coefficient of stone density (VCSD) measured by thresholding a three-dimensional (3D) segmentation-based method. Methods: Patients with urolithiasis treated at Keimyung University Dongsan Hospital between January 2017 and December 2020 were divided into training and internal validation sets, and patients from Kyungpook National University Hospital between January 2017 and December 2018 were used as an ex-ternal validation set. Each stone was segmented by a thresholding 3D segmentation-based method using an attenuation threshold of 130 Hounsfield units. VCSD was calculated as the stone heterogeneity index divided by the mean stone density.Results: A total of 1175 urinary stone cases in 1023 patients were enrolled in this study. Of these, 224 (19.1%) were pUA stone cases. Among the potential predictors, thresholding 3D segmentation-based VCSD, age, sex, radio-opacity, hypertension, diabetes, and urine pH were identified as independent pUA stone predictors, and VCSD was the most powerful indicator. The pUA stone prediction model showed good discrimination, yielding area under the receiver operating characteristic curve of 0.960 (95% confidence interval (CI): 0.940-0.979, P < 0.001), 0.931 (95% CI: 0.875-0.987, P < 0.001), and 0.938 (95% CI: 0.912- 0.965, P < 0.001) in the training, internal validation, and external validation sets, respectively.Conclusions: VCSD measured using 3D segmentation was a decisive independent predictive factor for pUA stones. Furthermore, the established prediction model with VCSD can serve as a noninvasive preoperative tool to identify pUA stones. | Song, Bong-Il; Lee, Jinny; Jung, Wonho; Kim, Bum Soo | Keimyung Univ, Dongsan Hosp, Sch Med, Dept Nucl Med, 1035 Dongdeok Ro, Daegu 41944, South Korea; Keimyung Univ, Dongsan Hosp, Dept Urol, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea | Song, Bong-il/LIC-9102-2024; Kim, Soo-Yeon/ADR-9663-2022 | 36164442800; 58477473500; 56150089500; 57202817150 | urokbs@knu.ac.kr; | COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | COMPUT METH PROG BIO | 0169-2607 | 1872-7565 | 240 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;COMPUTER SCIENCE, THEORY & METHODS;ENGINEERING, BIOMEDICAL;MEDICAL INFORMATICS | 2023 | 4.9 | 13.5 | 0.11 | 2025-06-25 | 1 | 1 | Pure uric acid stone; Variant coefficient of stone density; Noncontrast computed tomography; Segmentation; Prediction | COMPUTED-TOMOGRAPHY; URINARY CALCULI; HOUNSFIELD UNIT; KIDNEY; INDEX; SCAN; RISK; SIZE | Noncontrast computed tomography; Prediction; Pure uric acid stone; Segmentation; Variant coefficient of stone density | Humans; Retrospective Studies; ROC Curve; Tomography, X-Ray Computed; Uric Acid; Urinary Calculi; Computerized tomography; Decision making; Hospitals; Image segmentation; Organic acids; Patient treatment; uric acid; 3D segmentation; Noncontrast computed tomography; Prediction modelling; Pure uric acid stone; Segmentation; Thresholding; Uric acids; Urinary stones; Validation sets; Variant coefficient of stone density; adult; area under the curve; Article; bladder; clinical decision making; comparative study; computer assisted tomography; diabetes mellitus; diagnostic test accuracy study; discriminant validity; external validity; female; human; hypertension; image analysis; image segmentation; internal validity; major clinical study; male; mathematical analysis; multicenter study; multivariate analysis; nephrolithiasis; non invasive procedure; noncontrast computed tomography; predictive model; preoperative evaluation; receiver operating characteristic; retrospective study; three-dimensional imaging; two-dimensional imaging; univariate analysis; university hospital; ureter stone; urethra stone; uric acid stone; urine pH; urolithiasis; variant coefficient of stone density; clinical trial; diagnostic imaging; procedures; urolithiasis; x-ray computed tomography; Forecasting | English | 2023 | 2023-10 | 10.1016/j.cmpb.2023.107691 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Robot-patient registration for optical tracker-free robotic fracture reduction surgery | Background and objective: Image-guided robotic surgery for fracture reduction is a medical procedure in which surgeons control a surgical robot to align the fractured bones by using a navigation system that shows the rotation and distance of bone movement. In such robotic surgeries, it is necessary to estimate the relationship between the robot and patient (bone), a task known as robot-patient registration, to realize the navigation. Through the registration, a fracture state in real-world can be simulated in virtual space of the navigation system. Methods: This paper proposes an approach to realize robot-patient registration for an optical-tracker-free robotic fracture-reduction system. Instead of the optical tracker which is a three-dimensional position localizer, X-ray images are used to realize the robot-patient registration, combining the relationship of both the robot and patient with regards to C-arm. The proposed method consists of two steps of registration, where initial registration is followed by refined registration which adopts particle swarm optimization with the minimum cross-reprojection error based on bidirectional X-ray images. To address the unrecognizable features due to interference between the robot and bone, we also developed attachable robot features. The allocated robot features could be clearly extracted from the X-ray images, and precise registration could be realized through the particle swarm optimization. Results: The proposed method was evaluated in phantom and ex-vivo experiments involving a caprine cadaver. For the phantom experiments, the average translational and rotational errors were 1.88 mm and 2.45 degrees, respectively, and the corresponding errors in the ex vivo experiments were 2.64 mm and 3.32 degrees The results demonstrated the effectiveness of the proposed robot-patient registration. Conclusions: The proposed method enable to estimate the three-dimensional relationship between fractured bones in real-world by using only two-dimensional images, and the relationship is accurately simulated in virtual reality for the navigation. Therefore, a reduction procedure for successful treatment of bone fractures in image-guided robotic surgery can be expected with the aid of the proposed registration method. (C) 2022 Elsevier B.V. All rights reserved. | Ha, Ho-Gun; Han, Gukyeong; Lee, Seongpung; Nam, Kwonsun; Joung, Sanghyun; Park, Ilhyung; Hong, Jaesung | DGIST, Div Intelligent Robot, 333 Techno Jungang Daero, Daegu 42988, South Korea; Curexo Inc, R&D Ctr, 4-5,Yanghyeon Ro 405 Beon Gil, Seongnam Si 13438, Gyeonggi Do, South Korea; SAMICK THK Co Ltd, R&D Ctr, Jinwi2sandan Ro, Pyeongtaek Si 17708, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Med Device & Robot Inst Pk, Global Plaza 1006,80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ Hosp, Sch Med, Dept Orthopaed Surg, 130 Dongdeok Ro, Daegu 41944, South Korea; DGIST, Dept Robot & Mechatron Cs Engn, 333 Techno Jungang Daero, Daegu 42988, South Korea | 34872028500; 57976445000; 56493417900; 57457700400; 14628748500; 35076285100; 55825553700 | hogus@dgist.ac.kr; | COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | COMPUT METH PROG BIO | 0169-2607 | 1872-7565 | 228 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;COMPUTER SCIENCE, THEORY & METHODS;ENGINEERING, BIOMEDICAL;MEDICAL INFORMATICS | 2023 | 4.9 | 13.5 | 0.91 | 2025-06-25 | 9 | 9 | Fracture reduction; Image-guided robotic surgery; Robot-patient registration; Surgical navigation | IMAGE REGISTRATION; NAVIGATION; SYSTEM; FEMUR | Fracture reduction; Image-guided robotic surgery; Robot–patient registration; Surgical navigation | Animals; Fracture Fixation; Goats; Humans; Robotic Surgical Procedures; Robotics; Bone; Errors; Finite element method; Fracture; Medical imaging; Navigation systems; Particle swarm optimization (PSO); Phantoms; Surgical equipment; Transplantation (surgical); carbon fiber; polyetheretherketone; polymer; Fracture reduction; Fractured bones; Image-guided; Image-guided robotic surgery; Optical trackers; Patient registration; Robotics surgery; Robot–patient registration; Surgical navigation; X-ray image; algorithm; Article; bone; cadaver; ex vivo study; femur; fracture; fracture reduction; goat; human; image guided robotic surgery; nonhuman; particle swarm optimization; registration; robot assisted surgery; robot patient registraion; simulation; tibia; virtual reality; X ray; x-ray computed tomography; animal; fracture fixation; robotics; Robotic surgery | English | 2023 | 2023-01 | 10.1016/j.cmpb.2022.107239 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A machine learning model for predicting hepatocellular carcinoma risk in patients with chronic hepatitis B | Background Machine learning (ML) algorithms can be used to overcome the prognostic performance limitations of conventional hepatocellular carcinoma (HCC) risk models. We established and validated an ML-based HCC predictive model optimized for patients with chronic hepatitis B (CHB) infections receiving antiviral therapy (AVT).Methods Treatment-naive CHB patients who were started entecavir (ETV) or tenofovir disoproxil fumarate (TDF) were enrolled. We used a training cohort (n = 960) to develop a novel ML model that predicted HCC development within 5 years and validated the model using an independent external cohort (n = 1937). ML algorithms consider all potential interactions and do not use predefined hypotheses.Results The mean age of the patients in the training cohort was 48 years, and most patients (68.9%) were men. During the median 59.3 (interquartile range 45.8-72.3) months of follow-up, 69 (7.2%) patients developed HCC. Our ML-based HCC risk prediction model had an area under the receiver-operating characteristic curve (AUC) of 0.900, which was better than the AUCs of CAMD (0.778) and REAL B (0.772) (both p < .05). The better performance of our model was maintained (AUC = 0.872 vs. 0.788 for CAMD and 0.801 for REAL B) in the validation cohort. Using cut-off probabilities of 0.3 and 0.5, the cumulative incidence of HCC development differed significantly among the three risk groups (p < .001).Conclusions Our new ML model performed better than models in terms of predicting the risk of HCC development in CHB patients receiving AVT. | Lee, Hye Won; Kim, Hwiyoung; Park, Taeyun; Park, Soo Young; Chon, Young Eun; Seo, Yeon Seok; Lee, Jae Seung; Park, Jun Yong; Kim, Do Young; Ahn, Sang Hoon; Kim, Beom Kyung; Kim, Seung Up | Yonsei Univ, Coll Med, Dept Internal Med, 50-1 Yonsei Ro, Seoul 03722, South Korea; Yonsei Univ, Coll Med, Inst Gastroenterol, Seoul, South Korea; Severance Hosp, Yonsei Liver Ctr, Seoul, South Korea; Yonsei Univ, Ctr Clin Imaging Data Sci CCIDS, Dept Biomed Syst Informat, Coll Med, Seoul, South Korea; Yonsei Univ, Coll Comp, Dept Artificial Intelligence, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Internal Med, Bundang, South Korea; Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea | Kim, Kyung/I-5501-2015; Kim, Eun Young/JCE-3602-2023; Lee, Hye/D-9081-2016; Kim, Jung/L-9791-2019; Kim, Dong/F-4608-2014; Kim, Sun/L-4239-2013; LEE, JAE SEUNG/KHT-9575-2024; Park, Jun/HPH-3570-2023; SANG-HOON, AHN/AAV-2600-2020; Ahn, Sang Hoon/AFM-2603-2022 | 57200110315; 57203411277; 58486944100; 57191674344; 36089768300; 35234912400; 57204060462; 47861376300; 56119929100; 7401989551; 35302925200; 54933821200 | beomkkim@yuhs.ac;ksukorea@yuhs.ac; | LIVER INTERNATIONAL | LIVER INT | 1478-3223 | 1478-3231 | 43 | 8 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 6 | 13.6 | 0.54 | 2025-06-25 | 4 | 6 | antiviral therapy; chronic hepatitis B; entecavir; hepatocellular carcinoma; machine learning; performance; prediction; prognosis; risk prediction; tenofovir | ORAL ANTIVIRAL TREATMENT; NATURAL-HISTORY; SCORING SYSTEM; VIRUS | antiviral therapy; chronic hepatitis B; entecavir; hepatocellular carcinoma; machine learning; performance; prediction; prognosis; risk prediction; tenofovir | Antiviral Agents; Carcinoma, Hepatocellular; Female; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Tenofovir; alanine aminotransferase; albumin; alpha fetoprotein; aspartate aminotransferase; bilirubin; creatinine; entecavir; hepatitis B(e) antigen; tenofovir disoproxil; virus DNA; antivirus agent; tenofovir; adult; albumin blood level; alpha fetoprotein blood level; antiviral therapy; Article; cancer risk; chronic hepatitis B; cohort analysis; computer assisted tomography; controlled study; creatinine blood level; female; follow up; Hepatitis B virus; human; international normalized ratio; liver cell carcinoma; machine learning; major clinical study; male; nuclear magnetic resonance imaging; platelet count; practice guideline; prediction; prognosis; prothrombin time; chronic hepatitis B; complication; liver cell carcinoma; liver tumor; middle aged; retrospective study | English | 2023 | 2023-08 | 10.1111/liv.15597 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Electrocatalytic upcycling of plastic waste | Plastics, which are versatile and widely used materials, are being improperly disposed of in landfills or water bodies, leading to significant environmental damage. Traditional methods for plastic waste management, such as thermal decomposition and gasification, require high energy input. Recycling plastics back into their original form is a sustainable option, but demands high purity of recycled plastics and complex pre- and post-treatments. Electrochemical upcycling has recently emerged as a new alternative, which utilizes electrochemical reactions to transform plastic waste into valuable chemical compounds. Its advantages include the ability to operate under mild conditions, the use of eco-friendly energy sources, and increased energy efficiency. This review article provides an overview of electrochemical upcycling technologies for various types of waste plastics and explores their potential for generating value-added products. It also highlights the importance of understanding reaction mechanisms, electrochemical reaction systems, and catalyst development. We believe that the integration of electrochemical upcycling and chemical depolymerization has the potential to contribute to a circular economy and mitigate the environmental impact of plastic waste. The electrochemical upcycling of plastic waste offers a more efficient and safer means to produce value-added products under mild conditions. | Cho, Juhyun; Kim, Byeongyoon; Kwon, Taehyun; Lee, Kwangyeol; Choi, Sang-Il | Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, GreenNano Mat Res Ctr, Daegu 41566, South Korea; Korea Univ, Dept Chem & Res Inst Nat Sci, Seoul 02841, South Korea; Incheon Natl Univ INU, Dept Chem, Incheon 22012, South Korea | Choi, Sang-Il/N-7571-2013; Chung, Chan-Hwa/D-5194-2011; Kim, Byeongyoon/T-3659-2018; Kwon, Taehyun/AAH-9830-2021; Choi, Sangil/N-7571-2013 | 57198450723; 55532693200; 57190672792; 8510322900; 56167600800 | kylee1@korea.ac.kr;sichoi@knu.ac.kr; | GREEN CHEMISTRY | GREEN CHEM | 1463-9262 | 1463-9270 | 25 | 21 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2023 | 9.3 | 13.6 | 1.12 | 2025-06-25 | 33 | 34 | Decomposition; Elastomers; Energy efficiency; Environmental impact; Plastic products; Waste management; Electrocatalytic; Electrochemicals; Environmental damage; High purity; High-energy input; Landfill bodies; Plastics waste; Pre-treatments; Recycled plastics; Waterbodies; Plastic recycling | English | 2023 | 2023-10-30 | 10.1039/d3gc03337f | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Incidence and risk factors of tuberculosis in patients following gastrectomy or endoscopic submucosal dissection: a cohort analysis of country-level data | BackgroundGastric cancer adversely affects nutrition and immunity, while increasing the risk of tuberculosis (TB). This study investigated the incidence and risk factors for TB in gastric cancer patients who had undergone gastrectomy or endoscopic submucosal dissection (ESD).MethodsThis retrospective cohort study was conducted using Korean national insurance claims data. We defined three study groups (total gastrectomy, subtotal gastrectomy, and ESD) of patients diagnosed with gastric cancer plus a cancer-free control group. The latent TB infection (LTBI) screening status, TB incidence, and potential confounders in each cohort were analyzed, and the risk of TB was analyzed using a Cox proportional hazard model.ResultsLTBI tests were performed in less than 1% of all patients, and the TB incidence rates were 473.8, 287.4, 199.4, 111.1 events/100,000 person-years in the total gastrectomy, subtotal gastrectomy, ESD, and control cohorts, respectively. Compared to the control cohort, the total gastrectomy cohort showed the highest hazard ratio (HR) for TB incidence (HR: 2.896, 95% CI: 2.559-2.337), while the ESD cohort showed a significantly increased risk (HR: 1.578, 95% CI: 1.957-1.980). Age, body mass index, and lack of exercise were risk factors in all cohorts. Comorbidities were also considered risk factors, depending on the cohort type.ConclusionsPatients who underwent gastrectomy or ESD had an increased risk of TB, and this risk was correlated with the scope of gastrectomy. Considering the low rate of LTBI diagnostic tests and increased risk of TB in the study cohorts, more specific and practical guidelines for TB management are required for gastric cancer patients. | Park, Hae-Young; Choi, Sun Ha; Kim, Dohyang; Hwang, Jinseub; Kwon, Yeongkeun; Kwon, Jin-Won | Kyungpook Natl Univ, Coll Pharm, BK21 FOUR Community Based Intelligent Novel Drug D, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Daegu Univ, Dept Stat, Gyongsan 38453, South Korea; Korea Univ, Div Foregut Surg, Coll Med, Seoul, South Korea; Korea Univ, Ctr Obes & Metab Dis, Anam Hosp, Seoul, South Korea | Choi, Sun Ha/HPD-7234-2023 | 57203771734; 57199723585; 57218821860; 57189231296; 55970203000; 16202951700 | jwkwon@knu.ac.kr; | GASTRIC CANCER | GASTRIC CANCER | 1436-3291 | 1436-3305 | 26 | 3 | SCIE | GASTROENTEROLOGY & HEPATOLOGY;ONCOLOGY | 2023 | 6 | 13.6 | 0.5 | 2025-06-25 | 3 | 3 | Tuberculosis; Gastrectomy; Stomach neoplasms; Endoscopic mucosal resection | GASTRIC-CANCER; NUTRITIONAL CONSEQUENCES; INFECTION; MALNUTRITION; BURDEN | Endoscopic mucosal resection; Gastrectomy; Stomach neoplasms; Tuberculosis | Cohort Studies; Endoscopic Mucosal Resection; Gastrectomy; Gastric Mucosa; Humans; Incidence; Retrospective Studies; Risk Factors; Stomach Neoplasms; Treatment Outcome; Tuberculosis; capecitabine; cisplatin; docetaxel; doxorubicin; epirubicin; ethambutol; fluorouracil; irinotecan; isoniazid; methotrexate; oxaliplatin; paclitaxel; pyrazinamide; rifabutin; rifampicin; tegafur; adult; aged; Article; body mass; cancer free survival; chronic obstructive lung disease; cohort analysis; diabetes mellitus; endoscopic submucosal dissection; exercise; fasting blood glucose level; female; gastrectomy; human; hypertension; ICD-10; interferon gamma release assay; kidney failure; latent tuberculosis; liver disease; major clinical study; male; retrospective study; risk factor; skin manifestation; stomach cancer; systolic blood pressure; tuberculosis; adverse event; endoscopic mucosal resection; gastrectomy; incidence; risk factor; stomach mucosa; stomach tumor; treatment outcome; tuberculosis | English | 2023 | 2023-05 | 10.1007/s10120-023-01367-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Long-term outcomes of a phase II study of neoadjuvant imatinib in large gastrointestinal stromal tumors of the stomach | BackgroundNeoadjuvant treatment is recommended for large GISTs due to their friability and risk of extensive operations; however, studies on the indications and long-term results of this approach are lacking.MethodsPatients with large (& GE; 10 cm) gastric GISTs were enrolled from multiple centers in Korea and Japan after a pathologic confirmation of c-KIT ( +) GISTs. Imatinib (400 mg/d) was given for 6-9 months preoperatively, and R0 resection was intended. Postoperative imatinib was given for at least 12 months and recommended for 3 years.ResultsA total of 56 patients were enrolled in this study, with 53 patients receiving imatinib treatment at least once and 48 patients undergoing R0 resection. The 5-year overall survival and progression-free survival rates were 94.3% and 61.6%, respectively. Even patients with stable disease by RECIST criteria responded well to preoperative imatinib treatment and could undergo R0 resection, with most being evaluated as partial response by CHOI criteria. The optimal reduction in tumor size was achieved with preoperative imatinib treatment for 24 weeks or more. No resumption of imatinib treatment was identified as an independent prognostic factor for recurrence after R0 resection. No additional size criteria for a higher risk of recurrence were identified in this cohort with a size of 10 cm or more.ConclusionsNeoadjuvant imatinib treatment is an effective treatment option for gastric GISTs 10 cm or larger. Postoperative imatinib treatment is recommended even after R0 resection to minimize recurrence. | Kong, Seong-Ho; Kurokawa, Yukinori; Yook, Jeong-Hwan; Cho, Haruhiko; Kwon, Oh-Kyoung; Masuzawa, Toru; Lee, Kyung Hee; Matsumoto, Sohei; Park, Young Soo; Honda, Hiroshi; Ryu, Seung-Wan; Ishikawa, Takashi; Kang, Hye Jin; Nabeshima, Kazuhito; Im, Seock-Ah; Shimokawa, Toshio; Kang, Yoon-Koo; Hirota, Seiichi; Yang, Han-Kwang; Nishida, Toshirou | Seoul Natl Univ, Seoul Natl Univ Hosp, Canc Res Inst, Dept Surg,Coll Med, 101 Daehak Ro, Seoul 0380, South Korea; Osaka Univ, Dept Gastroenterol Surg, Grad Sch Med, Osaka, Japan; Univ Ulsan, Dept Surg, Coll Med, Asan Med Ctr, Seoul, South Korea; Kanagawa Canc Ctr, Dept Surg, Yokohama, Japan; Kyungpook Natl Univ, Chilgok Hosp, Dept Surg, Sch Med, Daegu, South Korea; Osaka Police Hosp, Dept Surg, Osaka, Japan; Yeungnam Univ, Dept Hematooncol, Coll Med, Daegu, South Korea; Nara Med Univ, Dept Surg, Nara, Japan; Univ Ulsan, Dept Pathol, Coll Med, Asan Med Ctr, Seoul, South Korea; Sendai Open Hosp, Dept Surg, Sendai, Japan; Keimyung Univ, Dept Surg, Dongsan Hosp, Daegu, South Korea; Niigata Univ, Dept Surg, Grad Sch Med & Dent Sci, Niigata, Japan; Korea Inst Radiol & Med Sci, Korea Canc Ctr Hosp, Dept Internal Med, Seoul, South Korea; Tokai Univ, Dept Surg, Hiratsuka, Kanagawa, Japan; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Coll Med, Canc Res Inst, Seoul, South Korea; Wakayama Med Univ Hosp, Clin Study Support Ctr, Wakayama, Japan; Univ Ulsan, Dept Oncol, Coll Med, Asan Med Ctr, Seoul, South Korea; Hyogo Med Univ, Dept Surg Pathol, Sch Med, Nishinomiya, Japan; Japan Community Hlth Care Org Osaka Hosp, Dept Surg, Osaka, Japan | Yang, Han-Kwang/J-2767-2012; Cho, Haruhiko/GPP-0808-2022; Kang, Yoon-Koo/ABL-4264-2022; Im, Seock-Ah/J-5620-2012 | 55641926600; 7202562410; 7006991559; 7403936699; 26536109900; 55237372700; 57196250869; 36179839900; 55540144700; 59825060000; 55420795900; 59090511000; 23497013500; 7006395760; 34570185300; 13009200300; 7402784198; 35391488400; 7406557280; 55535257500 | hkyang@snu.ac.kr; | GASTRIC CANCER | GASTRIC CANCER | 1436-3291 | 1436-3305 | 26 | 5 | SCIE | GASTROENTEROLOGY & HEPATOLOGY;ONCOLOGY | 2023 | 6 | 13.6 | 0.33 | 2025-06-25 | 2 | 2 | Gastrointestinal stromal tumor; Imatinib mesylate; Neoadjuvant; Stomach neoplasm | MESYLATE; RISK; RECURRENCE; SURGERY | Gastrointestinal stromal tumor; Imatinib mesylate; Neoadjuvant; Stomach neoplasm | Antineoplastic Agents; Benzamides; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Neoadjuvant Therapy; Piperazines; Pyrimidines; Stomach Neoplasms; alanine aminotransferase; aspartate aminotransferase; contrast medium; creatinine; imatinib; stem cell factor receptor; antineoplastic agent; benzamide derivative; imatinib; piperazine derivative; pyrimidine derivative; abdominal pain; abnormally high substrate concentration in blood; adult; aged; alanine aminotransferase blood level; anemia; Article; aspartate aminotransferase blood level; body weight loss; brain ischemia; cancer patient; cancer prognosis; cancer recurrence; central nervous system disease; clinical outcome; controlled study; creatinine blood level; decreased appetite; diarrhea; dizziness; drug dose reduction; drug eruption; drug fever; drug hypersensitivity; drug withdrawal; ear infection; eczema; edema; febrile neutropenia; female; gastrointestinal disease; gastrointestinal stromal tumor; hematologic disease; human; hypertransaminasemia; hypoxia; infection; infestation; Japan; Korea; leukopenia; lymphatic system disease; major clinical study; malaise; male; mediastinum disease; metabolic disorder; mucosa inflammation; nausea; neoadjuvant chemotherapy; neutropenia; nutritional disorder; overall survival; patient compliance; peripheral edema; phase 2 clinical trial; pneumonia; postoperative period; preoperative period; progression free survival; pruritus; recurrence free survival; recurrence risk; respiratory tract disease; response evaluation criteria in solid tumors; risk factor; side effect; skin disease; survival rate; thorax disease; treatment duration; treatment response; tumor volume; vomiting; clinical trial; gastrointestinal stromal tumor; neoadjuvant therapy; pathology; procedures; stomach tumor | English | 2023 | 2023-09 | 10.1007/s10120-023-01406-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Nanocellulose-based ammonia sensitive smart colorimetric hydrogels integrated with anthocyanins to monitor pork freshness | This study aims to develop green sustainable TEMPO-oxidized cellulose nanofibril (TOCNF)-based smart hydrogels triggered with different crosslinkers and anthocyanins (ACNs) from different sources for monitoring pork freshness. Al3+ was selected as an optimum crosslinker for TOCNF-based colorimetric freshness indicators (CFIs) and interestingly the resulting CFIs showed a critical color change in the neutral pH range; the pH range of the majority of animal-origin food. The response of the CFIs to ammonia was nonlinear and the limit of detection (LD) with naked eye inspection and instrumental color measurements was 150 and 50 ppm, 150 and 50 ppm, and 50 and 25 ppm for CFIs doped with Aronia, Liriope, and red cabbage ACNs, respectively. Based on the results of TVB-N, even very fresh pork comprises a considerable amount of ammonia, indicating CFIs with very low LD cannot be applicable for pork freshness evaluation. The cheap and environmentally friendly CFIs developed in this study could detect the pork warning stage and the medium fresh stages both qualitatively and quantitatively. The non-linear response of the CFIs to ammonia could indicate their potential to differentiate TVB-N mixtures contributing to the meat spoilage process. Based on these results, using a combination of resulting CFIs rather than using a single one could be a more effective tool for confrontation with complex cases like pork freshness evaluation. | Pirayesh, Hamidreza; Park, Byung-Dae; Khanjanzadeh, Hossein; Park, Hye-Jin; Cho, Young-Je | Kyungpook Natl Univ, Dept Wood & Paper Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea | Park, Byung-Dae/ABB-1934-2020; Khanjanzadeh, Hossein/B-7794-2018 | 37049319500; 7402834820; 37048874200; 7601567655; 55265396300 | byungdae@knu.ac.kr; | FOOD CONTROL | FOOD CONTROL | 0956-7135 | 1873-7129 | 147 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2023 | 5.6 | 13.6 | 5.1 | 2025-06-25 | 37 | 38 | TEMPO -oxidized cellulose nanofibril; Hydrogel; Anthocyanin; Colorimetric freshness indicator | INDICATOR FILM; RED CABBAGE; CELLULOSE | Anthocyanin; Colorimetric freshness indicator; Hydrogel; TEMPO-oxidized cellulose nanofibril | English | 2023 | 2023-05 | 10.1016/j.foodcont.2022.109595 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Turning Berlin green frameworks into cubic crystals for cathodes with high-rate capability | Prussian blue analogues (PBAs) have been considered as promising host frameworks for charge carriers because of their well-defined diffusion channel along the 100 direction. Among PBA families, Berlin green (BG) would be an ideal cathode platform because the empty carrier ion sites and two redox couples (Fe3+/2+-CN-Fe3+/2+) in the BG framework can deliver high specific capacity during battery operation. Nonetheless, in most solution-based precipitation processes, BG crystals are synthesized in irregular shapes rather than in well-defined cube shapes, thus limiting their capacities at high rate operations. In this work, given the aforementioned challenges, a simple two-step precipitation process to synthesize cubic BG without using any chelating agents and toxic acids was reported. Notably, an intermediate phase was identified as an important stage in converting irregularly shaped BG to cubic BG by releasing crystal water molecules from the framework. Utilizing well-aligned 100 channels in the cubic framework, cubic BG exhibits excellent electrochemical properties as a cathode for lithium-ion batteries, delivering a specific capacity of 107.2 mA h g(-1) at a high current density of 500 mA g(-1). A combined study of in situ X-ray diffraction and X-ray absorption fine structure analyses would provide a comprehensive structure-property relationship of BG cathodes. | Heo, Jeong Yeon; Lee, Ju-Hyeon; Bae, Jin-Gyu; Kim, Min Sung; Lee, Hyeon Jeong; Lee, Ji Hoon | Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, KNU Adv Mat Res Inst, Daegu 41566, South Korea; Ulsan Natl Inst Sci & Technol, Dept Mat Sci & Engn, Ulsan 44919, South Korea | ; Lee, Ju/M-8764-2019; Lee, Ji Hoon/T-4913-2017; Lee, Ji/AAU-7285-2021 | 58551045300; 57486987100; 57487313300; 58067058900; 56711412600; 55689885200 | hyeonjeong.lee@unist.ac.kr;jihoonlee@knu.ac.kr; | GREEN CHEMISTRY | GREEN CHEM | 1463-9262 | 1463-9270 | 25 | 17 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2023 | 9.3 | 13.6 | 0.45 | 2025-06-25 | 6 | 5 | PRUSSIAN BLUE ANALOGS; SODIUM-ION; HIGH-CAPACITY; LONG-LIFE; REDOX; HEXACYANOFERRATE; STABILITY; FE; INTERCALATION; ELECTROLYTE | Chelation; Lithium-ion batteries; Molecules; Precipitation (chemical); X ray absorption; Battery operation; Cubic crystal; Diffusion channels; Fe 3+; High rate capability; High specific capacity; Ion sites; Precipitation process; Prussian blue analogues; Redox couple; Cathodes | English | 2023 | 2023-08-29 | 10.1039/d3gc01797d | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Comparison of acid and alkaline pre-treatment on methane production from empty palm oil fruit bunches (OPEFB): Effect on characteristics, digester performance, and correlation of kinetic parameters | This paper focused on comparing the impact of two different chemical pretreatments on various characteristics of OPEFBs (i.e., physical, structural, and morphological properties), methane production, digestate characteristics, and kinetic modelling. The biochemical methane potential (BMP) test showed that alkaline-treated OPEFBs produced higher methane yields than acid-treated OPEFBs. Accordingly, the methane yields became far higher after NaOH pretreatment, showing 0.186-0.224 m3CH4/kg VSadded compared with 0.102 m3CH4/kg VSadded and 0.093-0.115 m3CH4/kg VSadded from untreated and acid-treated OPEFBs. The best treatment was alkaline pre-treatment of P2N3, which gave the highest methane yield increase (by 1.2-fold). The Scanning Electron Mi-croscopy and Energy Dispersive X-ray (SEM-EDX) results of acid-treated OPEFBs indicated disruption of cell wall and loss of some minerals. However, alkaline-treated OPEFBs have more pores due to silica and other chemicals releases (i.e., lignin, hemicellulose, etc.). The kinetic study showed that all models (i.e., modified Gompertz, logistic, and transference) were in good agreement with the experimental data. Both experimental data and models confirmed P2N3 (i.e., NaOH concentrations of 3.8%) as the best results, indicated by the highest lignin reduction and methane production. This study showed an excellent opportunity to digest alkaline-treated OPEFBS, yet more in-depth investigations with sustainability and circular economy perspectives are needed. | Suhartini, Sri; Rohma, Novita Ainur; Hidayat, Nur; Sunyoto, Nimas Mayang S.; Mardawati, Efri; Kasbawati; Mascruhin, Nanang; Idrus, Syazwani; Fitria; Jung, Young Hoon; Melville, Lynsey | Univ Brawijaya, Fac Agr Technol, Dept Agroind Technol, Malang, East Java, Indonesia; Univ Brawijaya, Sustainable Bioresources, Waste Technol & Bioecon SBistec Res Grp, Malang, East Java, Indonesia; Univ Padjadjaran, Fac Agroind Technol, Dept Agroind Technol, Sumedang, West Java, Indonesia; Hasanuddin Univ, Dept Math, Appl Math Lab, Makassar, Sulawesi, Indonesia; Natl Res & Innovat Agcy BRIN, Res Ctr Biomass & Bioprod, Cibinong, Jawa Barat, Indonesia; Univ Putra Malaysia, Fac Engn, Dept Civil Engn, Serdang 43400, Malaysia; Washington State Univ, Dept Biol Syst Engn, Richland, WA USA; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, 10, Daegu 41566, South Korea; Birmingham City Univ, Fac Comp Engn & Built Environm, Bioresource & Bioecon Res Grp, Birmingham, W Midlands, England; Univ Brawijaya, Fac Agr Technol, Dept Agroind Technol, Jl Vet, Malang 65145, Indonesia | Jung, Young/F-1703-2013; Kasbawati, Kasbawati/AAE-1656-2019; Sunyoto, Nimas Mayang Sabrina/JMB-4211-2023; melville, lynsey/AAZ-4090-2020; Suhartini, Sri/AAC-3161-2021; hidayat, nur/AAC-3550-2021 | 43462070300; 57349318300; 57205321638; 56524526800; 57190383504; 56419884100; 56426319000; 56586227800; 56480288300; 57218138516; 55550063700; 57209041504 | ssuhartini@ub.ac.id;ainurnovita0@gmail.com;nhidayat@ub.ac.id;nimas.sunyoto@ub.ac.id;kasbawati@unhas.ac.id;nana021@brin.go.id;wani@upm.edu.my;fnu.fitria@wsu.edu;younghoonjung@knu.ac.kr;Lynsey.Melville@bcu.ac.uk; | RENEWABLE ENERGY | RENEW ENERG | 0960-1481 | 1879-0682 | 215 | SCIE | ENERGY & FUELS;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2023 | 9 | 13.7 | 0.7 | 2025-06-25 | 6 | 9 | Anaerobic digestion; Chemical pretreatment; Delignification; Empty palm oil fruit bunches; Kinetic modelling | BIOGAS; BIOMASS | Anaerobic digestion; Chemical pretreatment; Delignification; Empty palm oil fruit bunches; Kinetic modelling | Alkalinity; Delignification; Fruits; Kinetics; Methane; Alkalinity; Anaerobic digestion; Delignification; Fruits; Kinetic theory; Kinetics; Lignin; Methane; Scanning electron microscopy; Silica; Sodium hydroxide; Acid treated; Alkalines; CH 4; Chemical pre-treatment; Empty palm oil fruit bunch; Kinetic models; Methane production; Methane Yield; Performance; Pre-treatments; alkalinity; anaerobic digestion; cell component; correlation; methane; performance assessment; reaction kinetics; Palm oil | English | 2023 | 2023-10 | 10.1016/j.renene.2023.119009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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