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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Sustainable bio-based dialdehyde cellulose for transforming crystalline urea-formaldehyde resins into amorphous ones to improve their performance | Sustainable bio-based dialdehyde cellulose (DAC) was employed to transform crystalline urea-formaldehyde (UF) resins into amorphous ones for simultaneouly improving their adhesion strength and formaldehyde emission. Serial samples of the UF resins modified with DAC during the resin synthesis were extracted to understand the chemical reactions between the DAC and UF species. Fourier transform infrared, 1H-nuclear magnetic resonance (NMR), and 13C NMR spectroscopies confirmed the occurrence of reactions between the DAC and UF species. As the synthesis proceeded, the crystallinity of the modified UF resins decreased from 51.7% to 17.4%, transforming the crystalline domains into amorphous ones. Thermograms showed that the DAC in the modified UF resins was decomposed at temperatures over 200 degrees C as degraded form, resulting in a lower cross-linking density than that of the neat UF resins. The adhesion strength of the modified UF resins was statistically similar to that of the neat UF resins, and the formaldehyde emission of the modified UF resins dramatically decreased to ti 64.6%. These results evidence the significant application potential of bio-based DAC in improving the sustainability and performance of UF resins. (c) 2022 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved. | Park, Seongsu; Park, Byung-Dae | Kyungpook Natl Univ, Dept Wood & Paper Sci, Daegu 41566, South Korea | Park, Byung-Dae/ABB-1934-2020 | 57220771754; 7402834820 | byungdae@knu.ac.kr; | JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY | J IND ENG CHEM | 1226-086X | 1876-794X | 113 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;ENGINEERING, CHEMICAL | 2022 | 6.1 | 15.8 | 0.93 | 2025-06-25 | 11 | 12 | Bio-based dialdehyde cellulose; UF resins; Crystallinity; Adhesion; Formaldehyde emission | CURE KINETICS; MOLECULAR-WEIGHT; MOLE RATIO; WOOD; ADHESIVES; STARCH; EMISSION; BEHAVIOR; POLYSACCHARIDES; NANOCRYSTALS | Adhesion; Bio-based dialdehyde cellulose; Crystallinity; Formaldehyde emission; UF resins | Cellulose; Crystallinity; Formaldehyde; Metabolism; Polyureas; Bond strength (materials); Cellulose; Crystallinity; Formaldehyde; Metabolism; Nuclear magnetic resonance spectroscopy; Urea; Urea formaldehyde resins; Bio-based; Bio-based dialdehyde cellulose; Cristallinity; Crystalline urea; Dialdehyde cellulose; Formaldehyde emission; Fourier transform infrared; Performance; Urea formaldehyde; Urea-formaldehyde resin; Adhesion | English | 2022 | 2022-09-25 | 10.1016/j.jiec.2022.05.012 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Synthesis and photodynamic effect of 3-substituted methyl pyropheophorbide-a derivatives as novel photodynamic therapeutic agents for cancer treatment | The unique ability of chlorophyll derivatives to accumulate in tumor tissues and cause a photodynamic effect under laser radiation has been successfully used in photodynamic therapy (PDT). Previous research on modified peripheral substituents in chlorophyll showed that the presence and position of substituents in chlorin derivatives remarkably affect biological activities. Herein, we synthesized methyl pyropheophorbide-a (MPPa) derivatives, which are chlorophyll-a derivatives with heterocyclic aromatic substituents or pyrazole moieties on the peripheral positions. Then, we examined the PDT effects of these new derivatives in vitro and in vivo. (c) 2021 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved. | Lee, Tae Heon; Kim, Hye Jeong; Lee, Bo-Ra; Lee, Sang Bong; Lee, Da-Sol; Han, Ye Ri; Kim, Kil Soo; Song, Young Kyu; Shim, Young Key; Park, Su-Jin; Kim, Dong-Won; Jeon, Yong Hyun | Res Ctr Dr i&B Co, Daejeon, South Korea; Daegu Gyeongbuk Med Innovat Fdn, Lab Anim Ctr, 80 Cheombok Ro, Daegu, South Korea; Daegu Gyeongbuk Med Innovat Fdn, New Drug Dev Ctr, 80 Chembok Ro, Daegu, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Vaccine Commercializat Ctr, Gyeongbuk Inst Bioind, 88 Saneodanjigil, Andong Si 36618, Gyeongbuk, South Korea; Woogene B&G Co LTD, 230 Jeongmunsongsan Ro, Hwasung Si, Gyonggi Do, South Korea; OSP Co LTD, 11,Saneopdanji Ro 2 Gil, Nonsan Si, Chungcheongnam, South Korea | Jeon, Yong/N-6910-2019; Kim, Seung/N-5248-2019; Kim, Dong/B-5639-2008; Han, Ye/ABB-5644-2020 | 57327387400; 57226604747; 59604892400; 57190304501; 57226045679; 57327672500; 35272034300; 57327672600; 55663939100; 57327108700; 57327672700; 16042453400 | ygsong@drinb.co.kr;jeon9014@dgmif.re.kr; | JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY | J IND ENG CHEM | 1226-086X | 1876-794X | 105 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;ENGINEERING, CHEMICAL | 2022 | 6.1 | 15.8 | 0.31 | 2025-06-25 | 4 | 4 | Methyl pyropheophorbide-a (MPPa); Fluorescence dye; Photodynamic therapy (PDT); Tumor targeted imaging; Theranostics | PHOTOSENSITIZING EFFICACY; PORPHYRIN; SERIES | Fluorescence dye; Methyl pyropheophorbide-a (MPPa); Photodynamic therapy (PDT); Theranostics; Tumor targeted imaging | Chlorophyll; Synthesis (chemical); Tumors; Fluorescence dyes; Methyl pyropheophorbide-a; Photodynamic effect; Photodynamic therapy; Pyropheophorbide a; Synthesis effects; Targeted imaging; Theranostics; Therapeutic agents; Tumor targeted imaging; Photodynamic therapy | English | 2022 | 2022-01-25 | 10.1016/j.jiec.2021.10.009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells | Cathepsin D (Cat D) is well known for its roles in metastasis, angiogenesis, proliferation, and carcinogenesis in cancer. Despite Cat D being a promising target in cancer cells, effects and underlying mechanism of its inhibition remain unclear. Here, we investigated the plausibility of using Cat D inhibition as an adjuvant or sensitizer for enhancing anticancer drug-induced apoptosis. Inhibition of Cat D markedly enhanced anticancer drug-induced apoptosis in human carcinoma cell lines and xenograft models. The inhibition destabilized Bcl-xL through upregulation of the expression of RNF183, an E3 ligase of Bcl-xL, via NF-kappa B activation. Furthermore, Cat D inhibition increased the proteasome activity, which is another important factor in the degradation of proteins. Cat D inhibition resulted in p62-dependent activation of Nrf2, which increased the expression of proteasome subunits (PSMA5 and PSMB5), and thereby, the proteasome activity. Overall, Cat D inhibition sensitized cancer cells to anticancer drugs through the destabilization of Bcl-xL. Furthermore, human renal clear carcinoma (RCC) tissues revealed a positive correlation between Cat D and Bcl-xL expression, whereas RNF183 and Bcl-xL expression indicated inverse correlation. Our results suggest that inhibition of Cat D is promising as an adjuvant or sensitizer for enhancing anticancer drug-induced apoptosis in cancer cells. | Seo, Seung Un; Woo, Seon Min; Im, Seung-Soon; Jang, Younghoon; Han, Eugene; Kim, Sang Hyun; Lee, Hongchan; Lee, Hyun-Shik; Nam, Ju-Ock; Gabrielson, Edward; Min, Kyoung-Jin; Kwon, Taeg Kyu | Keimyung Univ, Sch Med, Dept Immunol, Daegu 42601, South Korea; Keimyung Univ, Sch Med, Dept Physiol, Daegu 42601, South Korea; Changwon Natl Univ, Dept Biol & Chem, Chang Won 51140, South Korea; Keimyung Univ, Sch Med, Dept Internal Med, Daegu 42601, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Life Sci, BK21 Four KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Food Sci & Biotechnol, Daegu 41566, South Korea; Johns Hopkins Univ, Dept Pathol, Sch Med, Baltimore, MD 21231 USA; Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD 21231 USA; Daegu Gyeongbuk Med Innovat Fdn DGMIF, New Drug Dev Ctr, Daegu 41061, South Korea; Keimyung Univ, Ctr Forens Pharmaceut Sci, Daegu 42601, South Korea | 57195411399; 57199873466; 57211749547; 57192873452; 56942969800; 57210450420; 57210948333; 16316010200; 7201496105; 7005987375; 7201466928; 7202206057 | kjmin@dgmif.re.kr;kwontk@dsmc.or.kr; | CELL DEATH & DISEASE | CELL DEATH DIS | 2041-4889 | 13 | 2 | SCIE | CELL BIOLOGY | 2022 | 9 | 16.0 | 2.72 | 2025-06-25 | 32 | 32 | BREAST-CANCER; MOLECULAR-MECHANISMS; PROTEASOME ACTIVITY; PROTEIN EXPRESSION; BAX ACTIVATION; DEATH; AUTOPHAGY; PROLIFERATION; PROGRESSION; INHIBITION | Antineoplastic Agents; Apoptosis; bcl-X Protein; Carcinoma; Cathepsin D; Cell Line, Tumor; Humans; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; antineoplastic agent; cathepsin D; cytochrome c; etoposide; parkin; pepstatin; proteasome; protein bcl xl; reactive oxygen metabolite; rnf183 protein; sequestosome 1; small interfering RNA; sorafenib; trail; transcription factor Nrf2; ubiquitin protein ligase E3; unclassified drug; antineoplastic agent; cathepsin D; proteasome; protein bcl 2; protein bcl x; animal experiment; animal model; animal tissue; antineoplastic activity; apoptosis; Article; cell viability; chemosensitization; clinical article; controlled study; DNA fragmentation assay; drug potentiation; ectopic expression; gene knockout; human; human cell; human tissue; immunoprecipitation; kidney tissue; lysosome; male; mouse; nonhuman; protein expression; real time polymerase chain reaction; renal cell carcinoma; retrospective study; reverse transcription polymerase chain reaction; synergistic effect; tumor spheroid; tumor xenograft; apoptosis; carcinoma; metabolism; tumor cell line | English | 2022 | 2022-02-04 | 10.1038/s41419-022-04581-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5 | Ubiquitin-specific protease 1 (USP1) is a deubiquitinase involved in DNA damage repair by modulating the ubiquitination of major regulators, such as PCNA and FANCD2. Because USP1 is highly expressed in many cancers, dysregulation of USP1 contributes to cancer therapy. However, the role of USP1 and the mechanisms underlying chemotherapy remain unclear. In this study, we found high USP1 expression in tumor tissues and that it correlated with poor prognosis in RCC. Mechanistically, USP1 enhanced survivin stabilization by removing ubiquitin. Pharmacological inhibitors (ML23 and pimozide) and siRNA targeting USP1 induced downregulation of survivin expression. In addition, ML323 upregulated DR5 expression by decreasing miR-216a-5p expression at the post-transcriptional level, and miR-216a-5p mimics suppressed the upregulation of DR5 by ML323. Inhibition of USP1 sensitized cancer cells. Overexpression of survivin or knockdown of DR5 markedly prevented the co-treatment with ML323 and TRAIL-induced apoptosis. These results of in vitro were proved in a mouse xenograft model, in which combined treatment significantly reduced tumor size and induced survivin downregulation and DR5 upregulation. Furthermore, USP1 and survivin protein expression showed a positive correlation, whereas miR-216a-5p and DR5 were inversely correlated in RCC tumor tissues. Taken together, our results suggest two target substrates of USP1 and demonstrate the involvement of survivin and DR5 in USP1-targeted chemotherapy. | Woo, Seon Min; Kim, Seok; Seo, Seung Un; Kim, Shin; Park, Jong-Wook; Kim, Gyeonghwa; Choi, Yu-Ra; Hur, Keun; Kwon, Taeg Kyu | Keimyung Univ, Sch Med, Dept Immunol, Daegu 42601, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biochem & Cell Biol, Daegu 41944, South Korea; Keimyung Univ, Ctr Forens Pharmaceut Sci, Daegu 42601, South Korea | ; Hur, Keun/G-9513-2011; Park, Jung Hwan/AAA-1951-2022; Kim, Gyeonghwa/AAQ-6424-2021; Kim, Shin/D-1669-2013 | 57199873466; 57202820734; 57195411399; 57210866288; 55717085400; 57195957884; 57899145300; 8861888000; 7202206057 | kwontk@dsmc.or.kr; | CELL DEATH & DISEASE | CELL DEATH DIS | 2041-4889 | 13 | 9 | SCIE | CELL BIOLOGY | 2022 | 9 | 16.0 | 2.38 | 2025-06-25 | 26 | 28 | TRAIL-INDUCED APOPTOSIS; UBIQUITIN; MICRORNAS; PATHWAY | Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Renal Cell; Cell Line, Tumor; Deubiquitinating Enzymes; Down-Regulation; Humans; Kidney Neoplasms; Mice; MicroRNAs; Pimozide; Proliferating Cell Nuclear Antigen; RNA, Small Interfering; Survivin; Ubiquitin-Specific Proteases; Ubiquitins; Up-Regulation; antineoplastic agent; baculoviral IAP repeat containing protein 5; carboplatin; cisplatin; cycloheximide; death receptor 5; deubiquitinase; doxorubicin; etoposide; microRNA; microRNA 216a 5p; ml 323; n (2,4 dinitrophenyl) 5 methoxytryptamine; pimozide; proteinase inhibitor; small interfering RNA; tumor necrosis factor related apoptosis inducing ligand; ubiquitin; ubiquitin specific protease 1; unclassified drug; antineoplastic agent; baculoviral IAP repeat containing protein 5; cycline; deubiquitinase; microRNA; pimozide; small interfering RNA; ubiquitin; USP1 protein, human; A-549 cell line; ACHN cell line; animal experiment; animal model; antineoplastic activity; apoptosis; Article; Caki-1 cell line; cancer chemotherapy; cancer prognosis; cancer tissue; cell death; controlled study; down regulation; gene knockdown; gene overexpression; HCT 116 cell line; human; human cell; human tissue; in vitro study; major clinical study; male; molecularly targeted therapy; mouse; nonhuman; protein expression; renal cell carcinoma; SK-HEP-1 cell line; tumor volume; tumor xenograft; upregulation; animal; genetics; kidney tumor; metabolism; renal cell carcinoma; tumor cell line | English | 2022 | 2022-09-24 | 10.1038/s41419-022-05271-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Comparative Neural Network Based on Template Cluster for Automated Abnormal Beat Detection in Electrocardiogram Signals | Automatic abnormal beat detection reduces the time and cost for signal analysis by a cardiologist because abnormal beats rarely occur in an electrocardiogram (ECG) signal. However, the characteristics of normal and abnormal beats vary by individuals, which leads to misdetection. In this study, instead of directly training the input beats, we combine the input beats with corresponding reference normal beats and train the difference within combined beats. We can classify normal and abnormal beats through this approach, even if various types of individual normal and abnormal beats are mixed. The proposed comparative learning has the advantage of being able to classify multiple records using only one neural network. In experiments with learning five records, including premature ventricular contraction beats, we achieved 99.47% sensitivity and 99.28% accuracy for 30 records, with only one comparatively trained neural network. In addition, we confirmed that real-time processing is possible with an average processing time of 20.87 ms per beat. | Lee, Seungmin; Park, Daejin | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu, South Korea | 57200005388; 55463943600 | boltanut@knu.ac.kr; | HUMAN-CENTRIC COMPUTING AND INFORMATION SCIENCES | HUM-CENT COMPUT INFO | 2192-1962 | 12 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS | 2022 | 6.6 | 16.1 | 0.18 | 2025-06-25 | 2 | 2 | Electrocardiogram; Abnormal Beat Detection; Convolutional Neural Network (CNN); Comparative Learning; Binary Classifier; Template Cluster | GENERATION | Abnormal beat detection; Binary classifier; Comparative learning; Convolutional neural network (cnn); Electrocardiogram; Template cluster | Convolutional neural networks; Abnormal beat detection; Beat detection; Binary classifiers; Comparative learning; Convolutional neural network; Electrocardiogram signal; Network-based; Neural-networks; Template cluster; Electrocardiograms | English | 2022 | 2022-11-15 | 10.22967/hcis.2022.12.051 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Face Detection Using Haar Cascade Classifiers Based on Vertical Component Calibration | The growing significance of the security and human management fields attracts active research related to face detection and recognition systems. Among these face detection techniques based on machine learning, Haar cascade classifiers are widely used because of their high accuracy for human frontal faces. However, the Haar cascade classifiers have a limitation in that the processing time increases as the number of false positives increases because they detect human faces based on the sub-window operation. Therefore, in this paper, a preprocessing method based on a 2D Haar discrete wavelet transform is proposed for face detection. The proposed method improves the processing speed by reducing the number of false positives through a vertical component calibration process using the vertical and horizontal components. The results of the face detection experiments that use a public test dataset comprising 2,845 images showed that the proposed method improved the processing speed by 32.05% and reduced the number of false positives by 25.46%, compared with those of the histogram equalization that shows the best performance case among conventional filter-based pre-processing methods. In addition, the performance of the proposed method is similar to those of conventional image contraction-based methods. In an experiment using a private dataset, the proposed method showed a 53.85% reduction in the total number of false positives compared with that of the Gaussian filter while maintaining the total number of true positives. The F-1 score of the proposed method shows a 1.39% improvement compared with those of Lanczos-3 that shows the best performance case. | Choi, Cheol-Ho; Kim, Junghwan; Hyun, Jongkil; Kim, Younghyeon; Moon, Byungin | Kyungpook Natl Univ, Grad Sch Elect & Elect Engn, Daegu, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea | Choi, Cheol-Ho/GLQ-8365-2022; Moon, Byungin/ACE-5308-2022 | 57208281649; 57222321332; 56911778100; 57219317399; 55419717700 | bihmoon@knu.ac.kr; | HUMAN-CENTRIC COMPUTING AND INFORMATION SCIENCES | HUM-CENT COMPUT INFO | 2192-1962 | 12 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS | 2022 | 6.6 | 16.1 | 2.12 | 2025-06-25 | 8 | 23 | 2D Haar Wavelet Transform; Haar Cascade Classifiers; Face Detection; Vertical Component Calibration | 2D Haar Wavelet Transform; Face Detection; Haar Cascade Classifiers; Vertical Component Calibration | Classification (of information); Discrete wavelet transforms; Face recognition; Image enhancement; Processing; Statistical tests; 2d haar wavelet transform; Faces detection; False positive; Haar cascade classifiers; Haar wavelet transform; Performance; Pre-processing method; Processing speed; Vertical component; Vertical component calibration; Calibration | English | 2022 | 2022-03-15 | 10.22967/hcis.2022.12.011 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Serum biomarker-based osteoporosis risk prediction and the systemic effects of Trifolium pratense ethanolic extract in a postmenopausal model | Background Recent years, a soaring number of marketed Trifolium pratense (red clover) extract products have denoted that a rising number of consumers are turning to natural alternatives to manage postmenopausal symptoms. T. pratense ethanolic extract (TPEE) showed immense potential for their uses in the treatment of menopause complications including osteoporosis and hormone dependent diseases. Early diagnosis of osteoporosis can increase the chance of efficient treatment and reduce fracture risks. Currently, the most common diagnosis of osteoporosis is performed by using dual-energy x-ray absorptiometry (DXA). However, the major limitation of DXA is that it is inaccessible and expensive in rural areas to be used for primary care inspection. Hence, serum biomarkers can serve as a meaningful and accessible data for osteoporosis diagnosis. Methods The present study systematically elucidated the anti-osteoporosis and estrogenic activities of TPEE in ovariectomized (OVX) rats by evaluating the bone microstructure, uterus index, serum and bone biomarkers, and osteoblastic and osteoclastic gene expression. Leverage on a pool of serum biomarkers obtained from this study, recursive feature elimination with a cross-validation method (RFECV) was used to select useful biomarkers for osteoporosis prediction. Then, using the key features extracted, we employed five classification algorithms: extreme gradient boosting (XGBoost), random forest, support vector machine, artificial neural network, and decision tree to predict the bone quality in terms of T-score. Results TPEE treatments down-regulated nuclear factor kappa-B ligand, alkaline phosphatase, and up-regulated estrogen receptor beta gene expression. Additionally, reduced serum C-terminal telopeptides of type 1 collagen level and improvement in the estrogen dependent characteristics of the uterus on the lining of the lumen were observed in the TPEE intervention group. Among the tested classifiers, XGBoost stood out as the best performing classification model with the highest F1-score and lowest standard deviation. Conclusions The present study demonstrates that TPEE treatment showed therapeutic benefits in the prevention of osteoporosis at the transcriptional level and maintained the estrogen dependent characteristics of the uterus. Our study revealed that, in the case of limited number of features, RFECV paired with XGBoost model could serve as a powerful tool to readily evaluate and diagnose postmenopausal osteoporosis. | Quah, Yixian; Yi-Le, Jireh Chan; Park, Na-Hye; Lee, Yuan Yee; Lee, Eon-Bee; Jang, Seung-Hee; Kim, Min-Jeong; Rhee, Man Hee; Lee, Seung-Jin; Park, Seung-Chun | Kyungpook Natl Univ, Coll Vet Med, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, 80 Daehak Ro, Daegu 41566, South Korea; Univ Tunku Abdul Rahman, Ctr IoT & Big Data, Kampar 31900, Perak, Malaysia; Daegu Gyeongbuk Med Innovat Fdn, Lab Anim Ctr, Daegu, South Korea; Korea Inst Toxicol, Reprod & Dev Toxicol Res Grp, Daejeon, South Korea; Teazen Co Ltd, Jeollanam Do 59017, South Korea | Yixian, Quah/ABE-7629-2021; Park, Seung-Chun/AAV-3388-2021; Rhee, Man/O-5705-2016; Lee, Jun Young/CAI-2335-2022; Lee, Jung Bok/HHZ-3200-2022; Yuan Yee, Lee/ABH-8956-2022 | 55886933200; 57397100600; 57192425603; 57203798815; 57216526135; 39561084700; 59809844300; 57211035357; 58689440900; 7501832396 | lee.seungjin@kitox.re.kr;parksch@knu.ac.kr; | CHINESE MEDICINE | CHIN MED-UK | 1749-8546 | 17 | 1 | SCIE | INTEGRATIVE & COMPLEMENTARY MEDICINE;PHARMACOLOGY & PHARMACY | 2022 | 4.9 | 16.1 | 0.6 | 2025-06-25 | 5 | 4 | Machine learning; Osteoporosis; Postmenopause; Red clover; Trifolium pretense; XGBoost | OVARIECTOMIZED RATS; BONE METABOLISM; GENE-EXPRESSION; WOMEN; ISOFLAVONES; ESTROGEN; CLASSIFICATION; SELECTION; OBESITY; PROFILE | Machine learning; Osteoporosis; Postmenopause; Red clover; Trifolium pretense; XGBoost | alkaline phosphatase; carboxy terminal telopeptide; collagen type 1; estradiol; estrogen receptor beta; osteocalcin; osteoclast differentiation factor; osteoprotegerin; pomegranate extract; red clover extract; animal experiment; animal model; animal tissue; Article; artificial neural network; bone density; bone quality; bone volume fraction; chemical composition; classification algorithm; controlled study; cortical thickness (bone); cross validation; decision tree; drug dose comparison; extreme gradient boosting; female; gene expression; machine learning; nonhuman; ovariectomy-induced osteoporosis; postmenopause osteoporosis; random forest; rat; recursive feature elimination; support vector machine; trabecular number; trabecular separation; trabecular thickness; uterus index | English | 2022 | 2022-06-14 | 10.1186/s13020-022-00622-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Editorial Material | ASO Author Reflections: Prediction of Implant Size Based on Breast Volumetry Using Mammography and Breast MRI in DTI Breast Reconstruction | Kim, Young Seon; Cho, Hyun Geun; Kim, Jaeil; Park, Sung Joon; Kim, Hye Jung; Lee, Seung Eun; Yang, Jung Dug; Kim, Won Hwa; Lee, Joon Seok | Yeungnam Univ, Yeungnam Univ Hosp, Dept Radiol, Coll Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Radiol, Daegu, South Korea | Yang, Jung/R-7806-2019; LEE, JIN/Q-3108-2018 | 57192908764; 57211205767; 57211615348; 57749001100; 57203506201; 58983964200; 55171704700; 36081886500; 56496041000 | greenoaktree9@gmail.com;leejspo@knu.ac.kr; | ANNALS OF SURGICAL ONCOLOGY | ANN SURG ONCOL | 1068-9265 | 1534-4681 | 29 | 12 | SCIE | ONCOLOGY;SURGERY | 2022 | 3.7 | 16.2 | 0 | 2025-06-25 | 0 | 0 | Breast; Breast Neoplasms; Female; Humans; Magnetic Resonance Imaging; Mammaplasty; Mammography; Article; breast cancer; breast magnetic resonance imaging; breast reconstruction; female; human; mammography; prediction; preoperative evaluation; simple mastectomy; volumetry; breast; breast tumor; diagnostic imaging; mammography; nuclear magnetic resonance imaging | English | 2022 | 2022-11 | 10.1245/s10434-022-12025-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Editorial Material | ASO Author Reflections: Toward the Prediction of Peritoneal Recurrence After Curative Resection for Colon Cancer | Pedrazzani, Corrado; Turri, Giulia; Choi, Gyu Seog | Univ Verona, Div Gen & Hepatobiliary Surg, Verona Univ Hosp, Dept Surg Sci Dent Gynecol & Pediat, Verona, Italy; Kyungpook Natl Univ, Kyungpook Natl Univ Med Ctr, Colorectal Canc Ctr, Sch Med, Daegu, South Korea | Turri, Giulia/AAA-8971-2021 | 6602542489; 57203867916; 8058759100 | corrado.pedrazzani@univr.it; | ANNALS OF SURGICAL ONCOLOGY | ANN SURG ONCOL | 1068-9265 | 1534-4681 | 29 | 12 | SCIE | ONCOLOGY;SURGERY | 2022 | 3.7 | 16.2 | 0 | 2025-06-25 | 0 | 0 | METASTASES; SURGERY | Colonic Neoplasms; Humans; Peritoneal Neoplasms; Peritoneum; antineoplastic agent; cancer incidence; cancer recurrence; cancer screening; cancer surgery; colon cancer; colorectal cancer; high risk patient; human; hyperthermic intraperitoneal chemotherapy; lymph node metastasis; lymph vessel metastasis; Note; peritoneum metastasis; predictive value; second look surgery; tumor microenvironment; colon tumor; peritoneum; peritoneum tumor | English | 2022 | 2022-11 | 10.1245/s10434-022-12180-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | Editorial Material | ASO Visual Abstract: Prediction of Implant Size Based on Breast Volume Using Mammography with Fully Automated Measurement and Breast MRI | Kim, Young Seon; Cho, Hyun Geun; Kim, Jaeil; Park, Sung Joon; Kim, Hye Jung; Lee, Seung Eun; Yang, Jung Dug; Kim, Won Hwa; Lee, Joon Seok | Yeungnam Univ, Yeungnam Univ Hosp, Dept Radiol, Coll Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Radiol, Daegu, South Korea | Yang, Jung/R-7806-2019; LEE, JIN/Q-3108-2018 | greenoaktree9@gmail.com;leejspo@knu.ac.kr; | ANNALS OF SURGICAL ONCOLOGY | ANN SURG ONCOL | 1068-9265 | 1534-4681 | 29 | 12 | SCIE | ONCOLOGY;SURGERY | 2022 | 3.7 | 16.2 | 0 | English | 2022 | 2022-11 | 10.1245/s10434-022-12019-9 | 바로가기 | 바로가기 | 바로가기 | ||||||||||||
| ○ | Editorial Material | ASO Visual Abstract: Prediction of Metachronous Peritoneal Metastases After Radical Surgery for Colon Cancer: A Scoring System Obtained from an International Multicenter Cohort | Pedrazzani, Corrado; Turri, Giulia; Marrelli, Daniele; Kim, Hye Jin; Park, Eun Jung; Spolverato, Gaya; Foppa, Caterina; Spinelli, Antonino; Pucciarelli, Salvatore; Baik, Seung Hyuk; Choi, Gyu Seog | Univ Verona, Verona Univ Hosp, Dept Surg Sci Dent Gynecol & Pediat, Div Gen & Hepatobiliary Surg, Verona, Italy; Univ Siena, Policlin Scotte, Dept Surg, Siena, Italy; Kyungpook Natl Univ, Sch Med, Med Ctr, Colorectal Canc Ctr, Daegu, South Korea; Yonsei Univ, Gangnam Severance Hosp, Coll Med, Div Colon & Rectal Surg,Dept Surg, Seoul, South Korea; Univ Padua, Dept Surg Oncol & Gastroenterol, Gen Surg 3, Padua, Italy; Humanitas Univ, Dept Biomed Sci, Milan, Italy; IRCCS Humanitas Res Hosp, Div Colon & Rectal Surg, Milan, Italy | ; Park, Eun/W-1340-2019; Spinelli, Antonino/ABI-1441-2020; Turri, Giulia/AAA-8971-2021; Pucciarelli, Salvatore/J-5050-2018; Spolverato, Gaya/M-1965-2017; MARRELLI, DANIELE/K-5669-2016; Kim, Hye/W-1059-2019; PUCCIARELLI, SALVATORE/J-5050-2018; Foppa, Caterina/AAC-2327-2020 | corrado.pedrazzani@univr.it; | ANNALS OF SURGICAL ONCOLOGY | ANN SURG ONCOL | 1068-9265 | 1534-4681 | 29 | 12 | SCIE | ONCOLOGY;SURGERY | 2022 | 3.7 | 16.2 | 0 | English | 2022 | 2022-11 | 10.1245/s10434-022-12473-5 | 바로가기 | 바로가기 | 바로가기 | ||||||||||||
| ○ | ○ | Article | Emotional impact, task performance and task load of green walls exposure in a virtual environment | As the time spent indoors increases significantly due to the Coronavirus Disease 2019 (COVID-19) pandemic, creating an indoor environment to promote the health of occupants has become critical. Although green walls efficiently realize a healthy indoor environment, few studies have analyzed their impact on occupants based on the visual element of green walls. This study measures the emotional impact, task performance, and task load of the subjects according to four virtual experiments (a non-green wall, a freestanding green wall, two freestanding green walls, and a full-sized green wall). The results of the four experiments are as follows: (i) The visual elements of the green wall had an emotional impact on the occupants, which was verified through the Friedman test; (ii) the effect of the visual elements of the green wall on the task performance of the occupants was not verified by the one-way repeated measures analysis of variance (ANOVA); and (iii) the task load of the occupants influenced their task performance, which was verified by the repeated-measures ANOVA. This study can help determine the optimal type and area of green walls by considering their impact on the occupants as well as on the economic and constructional aspects of the indoor space. | Yeom, Seungkeun; Kim, Hakpyeong; Hong, Taehoon; Ji, Changyoon; Lee, Dong-Eun | Yonsei Univ, Dept Architecture & Architectural Engn, 50 Yonsei Ro, Seoul 03722, South Korea; Korea Real Estate Board, Green Bldg Res Inst, Seoul, South Korea; Kyungpook Natl Univ, Sch Architecture & Civil Engn, Daegu, South Korea | ; Hong, Taehoon/E-9169-2012 | 57211071902; 57199153903; 57969349700; 36537402100; 56605563300 | hong7@yonsei.ac.kr; | INDOOR AIR | INDOOR AIR | 0905-6947 | 1600-0668 | 32 | 1 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENGINEERING, ENVIRONMENTAL;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2022 | 5.8 | 16.2 | 2.34 | 2025-06-25 | 25 | 28 | emotional impact; freestanding green wall; green walls; task load; task performance; virtual reality | OFFICE BUILDINGS; INDOOR PLANTS; BENEFITS; HEALTH | Air Pollution, Indoor; COVID-19; Emotions; Humans; SARS-CoV-2; Task Performance and Analysis; Analysis of variance (ANOVA); Virtual reality; Friedman test; Healthy indoor environments; Indoor environment; Indoor space; Repeated measures; Task performance; Time-spent; Virtual experiments; Visual elements; emotion; human; indoor air pollution; task performance; COVID-19 | English | 2022 | 2022-01 | 10.1111/ina.12936 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Prediction of Implant Size Based on Breast Volume Using Mammography with Fully Automated Measurements and Breast MRI | Background Determination of implant size is crucial for patients with breast cancer undergoing one-stage breast reconstruction. The purpose of this study is to predict the implant size based on the breast volume measured by mammography (MG) with a fully automated method, and by breast magnetic resonance imaging (MRI) with a semi-automated method, in breast cancer patients with direct-to-implant reconstruction. Patients and Methods This retrospective study included 84 patients with breast cancer who underwent direct-to-implant reconstruction after nipple-sparing or skin-sparing mastectomy and preoperative MG and MRI between April 2015 and April 2019. Breast volume was measured using (a) MG with a fully automated commercial software and (b) MRI with an in-house semi-automated software program. Multivariable regression analyses including breast volume and patient weight (P < 0.05 in univariable analysis) were conducted to predict implant size. Results MG and MRI breast volume was highly correlated with both implant size (correlation coefficient 0.862 and 0.867, respectively; P values < 0.001) and specimen weight (correlation coefficient 0.802 and 0.852, respectively; P values < 0.001). Mean absolute difference between the MR breast volume and implant size was 160 cc, which was significantly higher than that between the MG breast volume and implant size of 118 cc (P < 0.001). On multivariable analyses, only breast volume measured by both MG and MRI was significantly associated with implant size in any implant type (all P values < 0.001). Conclusion Breast volume measured by MG and MRI can be used to predict appropriate implant size in breast cancer patients undergoing direct-to-implant reconstruction in an efficient and objective manner. | Kim, Young Seon; Cho, Hyun Geun; Kim, Jaeil; Park, Sung Joon; Kim, Hye Jung; Lee, Seung Eun; Yang, Jung Dug; Kim, Won Hwa; Lee, Joon Seok | Yeungnam Univ, Yeungnam Univ Hosp, Dept Radiol, Coll Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Radiol, Daegu, South Korea | LEE, JIN/Q-3108-2018; Yang, Jung/R-7806-2019 | 57192908764; 57211205767; 57211615348; 57749001100; 57203506201; 58983964200; 55171704700; 36081886500; 56496041000 | greenoaktree9@gmail.com;leejspo@knu.ac.kr; | ANNALS OF SURGICAL ONCOLOGY | ANN SURG ONCOL | 1068-9265 | 1534-4681 | 29 | 12 | SCIE | ONCOLOGY;SURGERY | 2022 | 3.7 | 16.2 | 0.61 | 2025-06-25 | 4 | 4 | RECONSTRUCTION; DENSITY | Breast Implants; Breast Neoplasms; Female; Humans; Magnetic Resonance Imaging; Mammaplasty; Mammography; Mastectomy; Nipples; Retrospective Studies; contrast medium; adult; aged; Article; automation; breast cancer; breast magnetic resonance imaging; cancer patient; controlled study; female; human; major clinical study; mammography; preoperative evaluation; retrospective study; size; skin-sparing mastectomy; volume; breast endoprosthesis; breast reconstruction; breast tumor; diagnostic imaging; mammography; mastectomy; nipple; nuclear magnetic resonance imaging; procedures | English | 2022 | 2022-11 | 10.1245/s10434-022-11972-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Prediction of Metachronous Peritoneal Metastases After Radical Surgery for Colon Cancer: A Scoring System Obtained from an International Multicenter Cohort | Background Since novel strategies for prevention and treatment of metachronous peritoneal metastases (mPM) are under study, it appears crucial to identify their risk factors. Our aim is to establish the incidence of mPM after surgery for colon cancer (CC) and to build a statistical model to predict the risk of recurrence. Patients and Methods Retrospective analysis of consecutive pT3-4 CC operated at five referral centers (2014-2018). Patients who developed mPM were compared with patients who were PM-free at follow-up. A scoring system was built on the basis of a logistic regression model. Results Of the 1423 included patients, 74 (5.2%) developed mPM. Patients in the PM group presented higher preoperative carcinoembryonic antigen (CEA) [median (IQR): 4.5 (2.5-13.0) vs. 2.7 (1.5-5.9), P = 0.001] and CA 19-9 [median (IQR): 17.7 (12.0-37.0) vs. 10.8 (5.0-21.0), P = 0.001], advanced disease (pT4a 42.6% vs. 13.5%; pT4b 16.2% vs. 3.2%; P < 0.001), and negative pathological characteristics. Multivariate logistic regression identified CA 19-9, pT stage, pN stage, extent of lymphadenectomy, and lymphovascular invasion as significant predictors, and individual risk scores were calculated for each patient. The risk of recurrence increased remarkably with score values, and the model demonstrated a high negative predictive value (98.8%) and accuracy (83.9%) for scores below five. Conclusions Besides confirming incidence and risk factors for mPM, our study developed a useful clinical tool for prediction of mPM risk. After external validation, this scoring system may guide personalized decision-making for patients with locally advanced CC. | Pedrazzani, Corrado; Turri, Giulia; Marrelli, Daniele; Kim, Hye Jin; Park, Eun Jung; Spolverato, Gaya; Foppa, Caterina; Spinelli, Antonino; Pucciarelli, Salvatore; Baik, Seung Hyuk; Choi, Gyu Seog | Univ Verona, Verona Univ Hosp, Dept Surg Sci Dent Gynecol & Pediat, Div Gen & Hepatobiliary Surg, Verona, Italy; Univ Siena, Dept Surg, Policlin Scotte, Siena, Italy; Kyungpook Natl Univ, Med Ctr, Colorectal Canc Ctr, Sch Med, Daegu, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Surg, Div Colon & Rectal Surg,Coll Med, Seoul, South Korea; Univ Padua, Dept Surg Oncol & Gastroenterol, Gen Surg 3, Padua, Italy; Humanitas Univ, Dept Biomed Sci, Milan, Italy; IRCCS Humanitas Res Hosp, Div Colon & Rectal Surg, Milan, Italy | Turri, Giulia/AAA-8971-2021; Park, Eun/W-1340-2019; Foppa, Caterina/AAC-2327-2020; MARRELLI, DANIELE/K-5669-2016; Spinelli, Antonino/ABI-1441-2020; PUCCIARELLI, SALVATORE/J-5050-2018; Pucciarelli, Salvatore/J-5050-2018; Kim, Hye/W-1059-2019; Spolverato, Gaya/M-1965-2017 | 6602542489; 57203867916; 6604017305; 57204567554; 56072952500; 41862392700; 56034434600; 7102473373; 7004411561; 57293077900; 8058759100 | corrado.pedrazzani@univr.it; | ANNALS OF SURGICAL ONCOLOGY | ANN SURG ONCOL | 1068-9265 | 1534-4681 | 29 | 12 | SCIE | ONCOLOGY;SURGERY | 2022 | 3.7 | 16.2 | 0.92 | 2025-06-25 | 6 | 6 | HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY; ADVANCED COLORECTAL-CANCER; HIGH-RISK; CYTOREDUCTIVE SURGERY; PLUS HIPEC; CARCINOMATOSIS; RECURRENCE; SURVIVAL; BENEFIT; INDEX | Carcinoembryonic Antigen; Colonic Neoplasms; Humans; Neoplasm Staging; Peritoneal Neoplasms; Prognosis; Retrospective Studies; antineoplastic agent; CA 19-9 antigen; capecitabine; capecitabine plus oxaliplatin; carcinoembryonic antigen; fluorouracil; carcinoembryonic antigen; adjuvant chemotherapy; aged; anastomosis leakage; Article; cancer staging; cancer surgery; cancer survival; colloid carcinoma; colon cancer; controlled study; diagnostic test accuracy study; female; follow up; human; length of stay; long term survival; lymph node dissection; lymph node metastasis; lymph vessel metastasis; major clinical study; male; maximum likelihood method; operation duration; overall survival; perineural invasion; peritoneum metastasis; postoperative complication; prediction; predictive value; preoperative evaluation; retrospective study; scoring system; surgical approach; surgical infection; tumor depth; clinical trial; colon tumor; multicenter study; peritoneum tumor; prognosis | English | 2022 | 2022-11 | 10.1245/s10434-022-12097-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Development of a three-dimensional macroporous sponge biocathode coated with carbon nanotube-MXene composite for high-performance microbial electrosynthesis systems | Microbial electrosynthesis (MES) is a renewable energy platform capable of reducing the carbon footprint by converting carbon dioxide/bicarbonate to useful chemical commodities. However, the development of feasible electrode structures, inefficient current densities, and the production of unfavorable electrosynthesis products remain a major challenge. To this end, a three-dimensional (3D) macroporous sponge coated with a carbon nanotube/MXene composite (CNT-MXene@Sponge) was evaluated as an MES cathode. The macroporous scaffold, together with intrinsic electrical conductivity, enhanced the charge transfer efficiency and selective microbial enrichment characteristics of the CNT-MXene@Sponge cathode resulted in an average current density of -324 mA m(-2), which was substantially higher than that of the uncoated (-100 mA m(-2)), CNT (-141 mA m(-2)), and MXene (-214 mA m(-2)) coated sponge electrode. The uniform 3D structure and abundant active sites of the coated material facilitated mass diffusion and microbial growth, which produced 1.5 orders of magnitude higher butyrate than the uncoated sponge. The high-throughput sequencing results showed the selective enrichment of electrogenic and butyrate-producing phylum, Firmicutes. These results suggest that the MES performance could be enhanced using the collective features of large-pore network structure, such as better conductivity, improved capacitance, and selective microbial enrichment. | Tahir, Khurram; Maile, Nagesh; Ghani, Ahsan Abdul; Kim, Bolam; Jang, Jiseon; Lee, Dae Sung | Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak ro, Daegu 41566, South Korea; Korea Radioact Waste Agcy, R&D Inst Radioact Wastes, 174 Gajeong ro, Daejeon 34129, South Korea | Maile, Nagesh/AFD-8838-2022; Tahir, Khurram/KFS-5321-2024 | 57207114377; 57193804539; 57218294089; 57208922438; 56611137400; 55568524907 | jsjang@korad.or.kr;daesung@knu.ac.kr; | BIOELECTROCHEMISTRY | BIOELECTROCHEMISTRY | 1567-5394 | 1878-562X | 146 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;BIOLOGY;BIOPHYSICS;ELECTROCHEMISTRY | 2022 | 5 | 16.4 | 2.67 | 2025-06-25 | 27 | 28 | MXene; Carbon nanotube; Biocathode; Microbial electrosynthesis; Butyrate | FUEL-CELL; ELECTRODE; GRAPHENE; ANODE; ACETATE; DEGRADATION; REDUCTION; TI3C2 | Biocathode; Butyrate; Carbon nanotube; Microbial electrosynthesis; MXene | Butyrates; Carbon Dioxide; Electric Conductivity; Electrodes; Nanotubes, Carbon; Carbon dioxide; Carbon footprint; Cathodes; Charge transfer; Coated materials; Scaffolds; butyric acid; carbon nanotube; titanium derivative; butyric acid derivative; carbon dioxide; Biocathodes; Butyrate; Chemical commodities; Electrode structure; Macroporous; Microbial electrosynthesis; Mxene; Performance; Renewable energies; Useful chemicals; Article; chemical structure; controlled study; current density; diffusion; electric conductivity; electrosynthesis; Firmicutes; high throughput sequencing; microbial growth; nonhuman; chemistry; electrode; Carbon nanotubes | English | 2022 | 2022-08 | 10.1016/j.bioelechem.2022.108140 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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