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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Effect of LiSbO3 and SrZrO3 doping on the piezoelectric properties and microstructural behavior of K0.5Na0.5NbO3 ceramics | The effect of LiSbO3 and SrZrO3 doping on the piezoelectric characteristics of K0.5Na0.5NbO3-based ceramics was studied. First, (1 - x)K0.5Na0.5NbO3-xLiSbO(3)-CuO (0.00 <= x <= 0.07) was synthesized and a single phase of perovskite was observed in the range of 0.00 <= x <= 0.05. As LiSbO3 content increased, the orthorhombic single phase changed to orthorhombic and tetragonal multiphase. TO-T decreased from 176 degrees C (x = 0.00) to 85 degree celsius (x = 0.05) and, the d(33) showed the highest value of 156 pC/N (x = 0.05). Next, (0.95K(0.5)Na(0.5)NbO(3)-0.05LiSbO(3))-xSrZrO(3)-CuO (0.00 <= x <= 0.05) was studied. All compositions were well synthesized as perovskite phases; orthorhombic and tetragonal mixed phases up to x = 0.02, rhombohedral, orthorhombic, and tetragonal mixed phases at x = 0.03 and 0.04; and rhombohedral and tetragonal phases at x = 0.05. TO-T decreased from 78 degree celsius (x = 0.00) to 32 degree celsius (x = 0.04), and TR-T was formed at 48 degree celsius (x = 0.05). The d(33) value at x = 0.04 was 288 pC/N and significantly reduced to 134 pC/N at x = 0.05. | Shin, Wooseop; Kim, Sumi; Kim, Eunji; Kim, Dokyum; Oh, Seong-Uk; Lee, Jung-A; Heo, Young-Woo; Lee, Joon-Hyung; Nahm, Sahn | Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Korea Univ, Dept Mat Sci & Engn, Seoul 02841, South Korea | ; Lee, Jung/AAP-7829-2021 | 58813528900; 58813647900; 57190963973; 57212308311; 57856319400; 55108410500; 7004298542; 57204923460; 57030636500 | joonlee@knu.ac.kr;snahm@korea.ac.kr; | JOURNAL OF THE KOREAN CERAMIC SOCIETY | J KOREAN CERAM SOC | 1229-7801 | 2234-0491 | 61 | 2 | SCIE | MATERIALS SCIENCE, CERAMICS | 2024 | 3.8 | 10.6 | 0.56 | 2025-05-07 | 2 | 2 | Lead-free piezoelectric ceramics; KNN-based; Doping; Phase transition; Piezoelectricity | FERROELECTRIC PROPERTIES; PHASE-TRANSITION; NIOBATE; TEMPERATURE; BOUNDARY | Doping; KNN-based; Lead-free piezoelectric ceramics; Phase transition; Piezoelectricity | Copper oxides; Crystallography; Lithium compounds; Niobium compounds; Perovskite; Piezoelectric ceramics; Potassium compounds; Sodium compounds; Strontium compounds; Zirconium compounds; D 33; KNN-based; Lead-free piezoelectric ceramic; Micro-structural; Mixed phase; Multiphases; Piezoelectric characteristics; Piezoelectric property; Single phasis; Synthesised; Piezoelectricity | English | 2024 | 2024-03 | 10.1007/s43207-023-00356-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Enhanced thermoelectric performance of TiS2 via large thermal conductivity reduction by solid solution alloying with TiSe2 | TiS2 is a transition metal dichalcogenide with semiconducting transport properties, and is considered a potential thermoelectric material owing to its relatively low lattice thermal conductivity originated from van der Waals stacking. In this study, the evolution of electrical and thermal transport properties of TiS2 by solid solution alloying with TiSe2 are investigated systematically regarding thermoelectric properties. A series of solid solution compositions of Ti(S1 - xSex)(2) (x = 0, 0.1, 0.2, 0.3, 0.4, and 0.5) polycrystalline samples was synthesized by a conventional solid-state reaction, wherein no secondary phase was formed. As x increased, the electrical conductivity and carrier concentration gradually increased, while the Seebeck coefficient decreased. Consequently, the power factor decreased. On the other hand, the lattice thermal conductivity is reduced largely to 0.96 W/mK for x = 0.5 at 300 K, compared to 2.3 W/mK for the pristine TiS2 sample. Consequently, the thermoelectric figure of merit zT of TiS2 was enhanced by solid solution allying with TiSe2, despite deterioration of the electrical transport properties. The maximum zT of 0.41 was observed for x = 0.4 (Ti(S0.6Se0.4)(2)) at 500 K. | Park, Sanghyun; Roh, Jong Wook; Park, Joontae; Cho, Hyungyu; Kang, Seung Min; Park, Okmin; Kim, Hyun-Sik; Kim, Sang-il | Univ Seoul, Dept Mat Sci & Engn, Seoul 02504, South Korea; Kyungpook Natl Univ, Sch Nano Mat Engn, Daegu 37224, Gyeongsangbug D, South Korea | 57191430853; 25638796100; 58686931000; 58182843700; 24765267300; 57609036600; 56526077500; 36171889900 | sang1.kim@uos.ac.kr; | JOURNAL OF THE KOREAN CERAMIC SOCIETY | J KOREAN CERAM SOC | 1229-7801 | 2234-0491 | 61 | 2 | SCIE | MATERIALS SCIENCE, CERAMICS | 2024 | 3.8 | 10.6 | 0.84 | 2025-05-07 | 3 | 3 | Thermoelectric; TiS2; Thermal conductivity reduction; Solid solution alloying | DICHALCOGENIDES; POWER | Solid solution alloying; Thermal conductivity reduction; Thermoelectric; TiS<sub>2</sub> | Alloying; Carrier concentration; Crystal lattices; Deterioration; Solid state reactions; Solidification; Thermoelectric equipment; Thermoelectricity; Transition metals; Electrical transport properties; Lattice thermal conductivity; Solid solution alloying; Thermal conductivity reductions; Thermo-Electric materials; Thermoelectric; Thermoelectric material; Thermoelectric performance; Transition metal dichalcogenides (TMD); Van der Waal; Solid solutions | English | 2024 | 2024-03 | 10.1007/s43207-024-00368-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Evaluation of electrical resistivity of cement-based materials using time domain reflectometry | Time domain reflectometry (TDR) is a widely used electromagnetic wave-based technique for evaluating the volumetric water content of soils, although its use for moisture measurement in cement-based materials is limited. This paper presents a comprehensive analysis of the electrical properties of cement pastes and cement paste-slime mixtures using TDR. Both TDR and electrical resistivity probes are used to estimate the electrical resistivities of various cement-based materials over their curing period. The study reveals that these properties are significantly influenced by curing time, water-cement ratio, and water-solid ratio. The experimental results demonstrate a consistent increase in electrical resistivity with curing time, underscoring the significant role of hydration-induced water evaporation and microstructural changes. Furthermore, the interpretation of characteristic voltages on the TDR waveform significantly influences resistivity estimates. Thus, this study highlights the potential of TDR in accurately evaluating the electrical resistivity of cement-based materials. | Lee, Dongsoo; Kim, Dong-Ju; Lee, Jong -Sub; Tutumluer, Erol; Byun, Yong-Hoon | Korea Univ, Sch Civil Environm & Architectural Engn, 145 Anam Ro, Seoul 02841, South Korea; Univ Illinois Urbana & Champaign, Dept Civil & Environm Engn, 205 North Mathews Ave, Urbana, IL 61801 USA; Kyungpook Natl Univ, Dept Agr Civil Engn, 80 Daehak Ro, Daegu 41566, South Korea | ; Tutumluer, Erol/O-2650-2019; Lee, Jong-Sub/G-2752-2012; Byun, Yong-Hoon/JKI-8441-2023 | 57483228200; 7409760881; 55690048400; 6603812780; 42761048000 | yhbyun@knu.ac.kr; | MEASUREMENT | MEASUREMENT | 0263-2241 | 1873-412X | 236 | SCIE | ENGINEERING, MULTIDISCIPLINARY;INSTRUMENTS & INSTRUMENTATION | 2024 | 5.6 | 10.6 | 2.14 | 2025-05-07 | 7 | 8 | Cement paste; Dielectric constant; Electrical resistivity; Slime; Time domain reflectometry | SOIL-WATER CONTENT; EARLY HYDRATION; CONDUCTIVITY; STRENGTH; MOISTURE; MORTAR; PROBE; PERIOD | Cement paste; Dielectric constant; Electrical resistivity; Slime; Time domain reflectometry | Cements; Curing; Dielectric materials; Electric conductivity; Permittivity measurement; Reflection; Reflectometers; Cement based material; Cement paste; Comprehensive analysis; Curing time; Electrical resistivity; Moisture Measurement; Slime; Time domain reflectometry; Volumetric water content; Wave based techniques; Time domain analysis | English | 2024 | 2024-08-15 | 10.1016/j.measurement.2024.115166 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Low-temperature sintered 0.5Pb(Ni1/3Nb2/3)O3-0.16PbZrO3-0.34PbTiO3 piezoelectric textured ceramics by Li2CO3 addition | BaTiO3(BT)-templated 0.5Pb(Ni1/3Nb2/3)O-3-0.16PbZrO(3)-0.34PbTiO(3) with 0.2 wt% Li2CO3 (PNN-PZT + LC) ceramics were successfully sintered at temperatures less than 1050 degrees C. Their structural, ferroelectric, and piezoelectric properties were systematically investigated as a function of amount of BT, which ranged from 2 to 10 vol%. The PNN-PZT + LC ceramics sintered at 1000 degrees C showed highly textured morphologies with preferred (0 0 1) orientation, having Lotgering factors (f(L)) of 85% and higher. When sintering temperature exceeded 1000 degrees C, the epitaxial grain growth of PNN-PZT + LC rhombohedral phase, driven by BT templates, was hindered by dramatically enlarged matrix grains. In situ X-ray diffractometry analyses are performed to identify phase transition behavior depending on temperature. Properties of d(33) (1180 pC/N) and k(p) (80.3%) were obtained for the 2 vol% BT-templated PNN-PZT + LC ceramic sintered at 1000 degrees C, along with ferroelectric properties of 2P(r) (56.1 mu C/cm(2)) and 2E(c) (1.26 kV/mm) at 3.5 kV/mm. High-resolution transmission electron microscopy and piezo-response force microscopy were utilized to investigate domain structure and epitaxial grain growth between templated BaTiO3 and matrix ceramics. The low-temperature sintered specimen showed an extremely large electrostrain characteristic (d(33)*) of 1215 pm/V at 1 kV/mm. Furthermore, textured multilayer piezoelectric actuators exhibited higher actuator performance and lower energy loss compared to untextured multilayer piezoelectric actuators, indicating their potential for use in piezoelectric actuator devices. | Cho, Seong Wook; Na, Yong-Hyeon; Baik, Jeong Min; Park, Hyeon Jun; Park, Kwi-Il; Jeong, Young Hun | Korea Inst Ceram Engn Technol, Elect Convergence Mat Ctr, Jinju Si 52851, Gyeongsangnam D, South Korea; Sungkyunkwan Univ, Sch Adv Mat Sci & Engn, Suwon, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu, Gyeongsangbuk D, South Korea | Baik, Jeong/E-9205-2010; Park, Kwiil/LKN-9445-2024 | 57223886823; 57215092980; 7006635116; 58859176900; 35280874200; 9043313100 | yhjeong@kicet.re.kr; | JOURNAL OF THE AMERICAN CERAMIC SOCIETY | J AM CERAM SOC | 0002-7820 | 1551-2916 | 107 | 6 | SCIE | MATERIALS SCIENCE, CERAMICS | 2024 | 3.8 | 10.6 | 0.94 | 2025-05-07 | 5 | 6 | low-temperature sintering; piezoelectric actuator; PNN-PZT; templated grain growth; textured piezoelectric ceramic | TEMPLATED GRAIN-GROWTH; RELAXATION BEHAVIOR; PERFORMANCE; SIZE; POINT; CUO | low-temperature sintering; piezoelectric actuator; PNN-PZT; templated grain growth; textured piezoelectric ceramic | Barium titanate; Energy dissipation; Ferroelectric ceramics; Ferroelectricity; High resolution transmission electron microscopy; Lead zirconate titanate; Lithium compounds; Multilayers; Niobium compounds; Piezoelectric actuators; Piezoelectricity; Sintering; Temperature; X ray diffraction analysis; BaTiO 3; D 33; Epitaxial grains; Low temperature sintered; Low-temperature sintering; Pnn-pzt; PNN/PZT; Templated; Templated grain growth; Textured piezoelectric ceramic; Grain growth | English | 2024 | 2024-06 | 10.1111/jace.19720 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Nanotechnology-powered innovations for agricultural and food waste valorization: A critical appraisal in the context of circular economy implementation in developing nations | Nanotechnology is revolutionizing agricultural and food waste in underdeveloped countries via sustainable agriculture and circular economy application. This review critically assesses nanotechnology-powered technologies' ability to solve agricultural waste management and resource utilization problems. With its nanoscale specific engineering, nanotechnology provides remarkable waste valorization efficiency improvements. Advanced sensors for real-time agricultural process monitoring, resource optimization, and waste reduction are possible using nanomaterials and nanodevices. Nanocatalysts also convert organic waste into biofuels and biobased compounds, supporting the circular economy. The study focuses nanotechnology-enabled precision farming, which boosts agricultural yields while reducing resource inputs. Targeted and regulated fertilizer and pesticide nanoscale delivery technologies reduce environmental impact and optimize nutrient use. Nanosensors in agricultural systems provide data-driven sustainable farming decisions. The critical evaluation emphasizes responsible and inclusive nanotechnology deployment in emerging countries and its socio-economic effects. Environmental and health problems must be addressed to successfully integrate nanotechnology into agriculture. The study suggests strategic nanotechnology integration in poor countries' agricultural sectors to revolutionize waste valorization, resource efficiency, and circular economy implementation. The report emphasizes the need for academics, policymakers, and stakeholders to work together to responsibly and ethically use nanotechnology for sustainable agricultural growth. | Preethi, Balakrishnan; Karmegam, Natchimuthu; Manikandan, Sivasubramanian; Vickram, Sundaram; Subbaiya, Ramasamy; Rajeshkumar, Shanmugam; Gomadurai, Chinnasamy; Govarthanan, Muthusamy | Saveetha Inst Med & Tech Sci SIMATS, Saveetha Sch Engn, Dept Biotechnol, Chennai 602105, Tamil Nadu, India; Govt Arts Coll, PG & Res Dept Bot, Salem 636007, Tamil Nadu, India; Copperbelt Univ, Sch Math & Nat Sci, Dept Biol Sci, Riverside,POB 21692,Jambo Dr, Kitwe, Zambia; Saveetha Inst Med & Tech Sci, Saveetha Med Coll & Hosp, Ctr Global Hlth Res, Nanobiomed Lab, Chennai 602105, Tamil Nadu, India; Kongu Engn Coll, Dept Chem Engn, Erode 638060, Tamil Nadu, India; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Saveetha Univ, Saveetha Inst Med & Tech Sci, Saveetha Dent Coll & Hosp, Dept Biomat, Chennai 600077, India | Karmegam, Natchimuthu/J-4745-2019; Chinnasamy, Gomadurai/AAL-6574-2020; S, Manikandan/GZM-7135-2022; Natchimuthu, Karmegam/J-4745-2019; Shanmugam, Rajeshkumar/IUQ-2179-2023; Muthusamy, Govarthanan/C-1491-2014; Subbaiya, R/AAR-2948-2021; S, Vickram/ABG-9459-2020 | 57233833500; 6506043230; 55213168500; 55257689800; 55263515700; 57195616808; 56380555100; 54881927600 | manikandans.research@gmail.com;gova.muthu@gmail.com; | PROCESS SAFETY AND ENVIRONMENTAL PROTECTION | PROCESS SAF ENVIRON | 0957-5820 | 1744-3598 | 184 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2024 | 7.8 | 10.6 | 2.77 | 2025-05-07 | 23 | 29 | Agricultural waste; Energy production; Nanotechnology; Sustainable development; Waste valorization | ENVIRONMENTAL BENEFITS; BY-PRODUCTS; CONVERSION; HEALTH | Agricultural waste; Energy production; Nanotechnology; Sustainable development; Waste valorization | English | 2024 | 2024-04 | 10.1016/j.psep.2024.01.100 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Strategic conversion of plastic containers with food waste into energy through thermochemical processes | Plastic valorization has received particular attention as an environmentally benign approach to achieve carbon neutrality and reduce greenhouse gas emissions. However, contaminated plastic and biomass waste mixtures suffer from single-stream recycling. Waste mixtures are currently discarded through landfilling and incineration. As a sustainable disposal and valorization method for converting plastic and biomass waste mixtures into energyintensive products, especially syngas (H2 and CO), this study utilizes catalytic pyrolysis and a CO2 flow gas. A plastic container contaminated with a food waste mixture (PFW) was used as the model waste. The major products of the pyrolysis of PFW were liquid hydrocarbons (HC) (C7-30) and wax-like HCs with negligible formation of oxygen-containing HCs. However, the high production of wax-like HCs becomes a problem. Catalytic pyrolysis was employed to convert HCs into simpler product streams such as syngas. Although syngas formation tripled with the Ni catalyst, catalyst deactivation was observed. To suppress catalyst deactivation and promote CO formation, CO2 was introduced instead of N2. During the CO2-assisted catalytic pyrolysis, the syngas yield from PFW increased to 95.5 % because the chemical reactions between CO2 and liquid/wax-like HCs produced additional H2 and CO. The catalytic reaction with CO2 suppressed carbon deposition because long-chain HCs were converted to CO rather than coke. | Kwon, Dohee; Choi, Dongho; Tsang, Yiu Fai; Chen, Wei-Hsin; Jung, Sungyup; Kwon, Eilhann | Hanyang Univ, Dept Earth Resources & Environm Engn, Seoul 04763, South Korea; Educ Univ Hong Kong, Dept Sci & Environm Studies, Hong Kong 999077, New Territories, Peoples R China; Natl Cheng Kung Univ, Dept Aeronaut & Astronaut, Tainan 701, Taiwan; Tunghai Univ, Res Ctr Smart Sustainable Circular Econ, Taichung 407, Taiwan; Natl Chin Yi Univ Technol, Dept Mech Engn, Taichung 411, Taiwan; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea | Kwon, Eilhann/A-1225-2012; Jung, Sungyup/GZG-6207-2022; Tsang, Yiu/AAJ-2524-2020; Choi, Dongho/LTY-8225-2024; Chen, Wei-Hsin/S-2033-2018 | 57208275497; 57200013497; 22954605700; 57200873137; 55073290800; 9240622100 | sjung001@knu.ac.kr;ek2148@hanyang.ac.kr; | PROCESS SAFETY AND ENVIRONMENTAL PROTECTION | PROCESS SAF ENVIRON | 0957-5820 | 1744-3598 | 192 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2024 | 7.8 | 10.6 | 0 | 2025-05-07 | 0 | 0 | Waste Valorization; Plastic Packaging Waste; Food Wastes; Co-Pyrolysis; Carbon dioxide | MIXED-PLASTICS; FAST PYROLYSIS; OIL; DEGRADATION; CATALYST; PAHS; FUEL | Carbon dioxide; Co-Pyrolysis; Food Wastes; Plastic Packaging Waste; Waste Valorization | Effluent treatment; Fluid catalytic cracking; Incineration; Land fill; Plastic recycling; Catalytic pyrolysis; Copyrolysis; Energy; Food waste; Packaging waste; Plastic packaging; Plastic packaging waste; Syn gas; Waste mixtures; Waste valorizations; Plastic containers | English | 2024 | 2024-12 | 10.1016/j.psep.2024.10.008 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Tailored spherical-sea urchin-like MnO2-AC/PTA nanocomposites for superior photocatalytic degradation of BPA and Orange II dye, along with bacteria Inactivation: Mechanistic insights | In this study, we present a pioneering approach introducing a novel spherical-sea urchin-like MnO2-KAFC/PTA (Manganese dioxide/KOH activated foam derived carbon/Phosphotugstic acid) nanocomposite photocatalyst for photocatalytic degradation of organic pollutants and bacteria inactivation. It is well-established that the reactivity in photocatalytic applications heavily relies on the shape and crystallographic orientation of the photocatalysts. Thus, we synthesized controllable MnO2-KAFC/PTA NCs with spherical-sea urchin-like morphologies using the in-situ precipitation method. Subsequently, the synthesized KAFC, MnO2 NPs, and spherical-sea urchinlike MnO2-KAFC/PTA NCs were systematically characterized in detail. Following characterization, they were employed as photocatalysts for photocatalytic degradation of Bisphenol A (BPA) and Orange II dye pollutants, as well as for the inactivation of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The spherical-sea urchin-like MnO2-KAFC/PTA NCs photocatalyst demonstrated outstanding photocatalytic degradation efficiency, achieving rates of 99.8% and 99.9% for BPA and Orange II dye, respectively, under sunlight irradiation. Notable, the spherical-sea urchin-like MnO2-KAFC/PTA NCs exhibited excellent degradation efficiency (99.8 and 99.9%) compared to MnO2 NPs (40 and 51%), and KAFC (26 and 21%), respectively. Furthermore, the optimized spherical-sea urchin-like MnO2-KAFC/PTA NCs photocatalysts were subjected to bactericidal testing against E. coli and S. aureus pathogens. The results revealed that the optimal antibacterial efficacy against E.coli and S. aureus microbes was zone inhibition up to 18 mm and 20 mm, respectively. Overall, the present study underscores the efficacy of spherical-sea urchin-like MnO2-KAFC/PTA NCs as potent antibacterial and degrading agents. | Manikandan, Velu; Ganesan, Sivarasan; Devanesan, Sandhanasamy; Kim, Woong; Mythili, R.; Song, Kwang Soup | Kumoh Natl Inst Technol, Dept Med IT Convergence Engn, Gumi, South Korea; Chaoyang Univ Technol, Dept Environm Engn & Management, Taichung, Taiwan; King Saud Univ, Coll Sci, Dept Phys & Astron, POB 2455, Riyadh 11451, Saudi Arabia; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Saveetha Inst Med & Tech Sci SIMATS, Saveetha Dent Coll, Ctr Transdisciplinary Res, Dept Pharmacol, Chennai 600077, Tamil Nadu, India | MANIKANDAN, VELU/HGC-1674-2022; Devanesan, Sandhanasamy/ABH-3378-2021; Devanesan, Dr. Sandhanasamy/ABH-3378-2021; Ganesan, Sivarasan/AAH-7822-2019 | 57191158258; 57209250526; 55279721800; 55581636400; 56765761500; 7401740642 | kssong10@kumoh.ac.kr; | PROCESS SAFETY AND ENVIRONMENTAL PROTECTION | PROCESS SAF ENVIRON | 0957-5820 | 1744-3598 | 184 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2024 | 7.8 | 10.6 | 2.37 | 2025-05-07 | 8 | 8 | Spherical-sea urchin-like morphology; MnO2-KAFC/PTA NCs; BPA and Orange II dye degradation; Bacteria inactivation; Degradation mechanism | CARBON SPHERE; MNO2 | Bacteria inactivation; BPA and Orange II dye degradation; Degradation mechanism; MnO<sub>2</sub>-KAFC/PTA NCs; Spherical-sea urchin-like morphology | Biodegradation; Citrus fruits; Degradation; Efficiency; Foams; Mammals; Manganese oxide; Morphology; Nanocomposites; Organic pollutants; Precipitation (chemical); Spheres; Bacteria inactivation; Bisphenol A; Bisphenol A and orange II dye degradation; Bisphenols-A; Degradation mechanism; Dye degradation; MnO2-KAFC/PTA NC; Orange II; Sea urchin-like; Spherical-sea urchin-like morphology; Escherichia coli | English | 2024 | 2024-04 | 10.1016/j.psep.2024.02.054 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A Military Audio Dataset for Situational Awareness and Surveillance | Audio classification related to military activities is a challenging task due to the high levels of background noise and the lack of suitable and publicly available datasets. To bridge this gap, this paper constructs and introduces a new military audio dataset, named MAD, which is suitable for training and evaluating audio classification systems. The proposed MAD dataset is extracted from various military videos and contains 8,075 sound samples from 7 classes corresponding to approximately 12 hours, exhibiting distinctive characteristics not presented in academic datasets typically used for machine learning research. We present a comprehensive description of the dataset, including its acoustic statistics and examples. We further conduct a comprehensive sound classification study of various deep learning algorithms on the MAD dataset. We are also releasing the source code to make it easy to build these systems. The presented dataset will be a valuable resource for evaluating the performance of existing algorithms and for advancing research in the field of acoustic-based hazardous situation surveillance systems. | Kim, June-Woo; Yoon, Chihyeon; Jung, Ho-Young | Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 41566, South Korea | 57219550643; 58719553700; 57198760619 | hoyjung@knu.ac.kr; | SCIENTIFIC DATA | SCI DATA | 2052-4463 | 11 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 6.9 | 10.7 | 3.15 | 2025-05-07 | 1 | 3 | ACOUSTIC SCENES; CLASSIFICATION; EVENTS; MODELS | Acoustics; Algorithms; Awareness; Deep Learning; Humans; Military Personnel; Sound; acoustics; algorithm; awareness; deep learning; human; military personnel; sound | English | 2024 | 2024-06-22 | 10.1038/s41597-024-03511-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Clinical characteristics and outcomes of COVID-19 in child-ren and adolescents with diabetes in Daegu, South Korea | Purpose: Children with comorbidities have a higher risk of severe, coronavirus disease 2019 (COVID-19). This study investigated the clinical features and outcomes of COVID-19 in children and adolescents with diabetes between January and March 2022. Methods: We retrospectively reviewed the medical records of 123 children and adolescents (73 with type 1 diabetes and 50 with type 2 diabetes, 59 males and 64 females) aged <18 years who had been diagnosed with diabetes. Data were collected from 7 academic medical centers in Daegu, South Korea. Results: Thirty-five children with diabetes were diagnosed with COVID-19 (18 with type 1 and 17 with type 2 diabetes). Eighteen of the 35 children with diabetes and COVID-19 and 50 of the 88 children with diabetes alone received a COVID-19 vaccination. No significant differences were observed between patients with diabetes and COVID-19 and patients with diabetes alone in the type of diabetes diagnosed, sex, age, body mass index, hemoglobin A1c, or vaccination status. All children with diabetes and COVID-19 had mild clinical features and were safely managed in their homes. Fourteen children had a fever of 38degree celsius or higher that lasted for more than 2 days, 11 of whom were not vaccinated (P=0.004). None experienced post-COVID-19 conditions. Conclusion: All children and adolescents with pre-existing diabetes had mild symptoms of COVID-19 due to low disease severity, high vaccination rates, uninterrupted access to medical care, and continuous glucose monitoring. Unvaccinated children with diabetes who experienced COVID-19 presented with higher and more frequent fevers compared to vaccinated children. | Lee, Na-Won; Kim, You-Min; Kim, Young-Hwan; Kang, Seok-Jin; Jang, Kyung-Mi; Kim, Hae- Sook; Moon, Jung-Eun; Kim, Jin-Kyung | Daegu Catholic Univ, Daegu Catholic Univ Hosp, Dept Pediat, Sch Med, Daegu, South Korea; Keimyung Univ, Keimyung Univ Hosp, Sch Med, Dept Pediat, Daegu, South Korea; Yeungnam Univ, Sch Med, Dept Pediat, Yeungnam Univ Hosp, Daegu, South Korea; Daegu Fatima Hosp, Dept Pediat, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Univ Hosp, Sch Med, Dept Pediat, 130 Dongdeok Ro, Daegu 41944, South Korea | Yul, Kim/AAA-8586-2021; Kang, Seok-jin/KHX-7614-2024; kim, yang hee/HKW-3475-2023 | 58790792200; 57210427802; 57196174192; 57226565920; 57203762745; 59224382900; 57205770947; 36012293800 | subuya@hanmail.net;kimjk@cu.ac.kr; | ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | ANN PEDIATR ENDOCRIN | 2287-1012 | 2287-1292 | 29 | 3 | ESCI | ENDOCRINOLOGY & METABOLISM;PEDIATRICS | 2024 | 3.3 | 10.7 | 0.81 | 2025-05-07 | 1 | 1 | COVID-19; SARS-CoV-2; Diabetes mellitus | COVID-19; Diabetes mellitus; SARS-CoV-2 | hemoglobin A1c; insulin; metformin; adolescent; Article; child; coronavirus disease 2019; coughing; diabetes mellitus; female; fever; glucose blood level; headache; hospitalization; human; insulin dependent diabetes mellitus; insulin treatment; male; mental health; myalgia; nasopharyngeal swab; non insulin dependent diabetes mellitus; obesity; outcome assessment; oxygen saturation; retrospective study; reverse transcription polymerase chain reaction; rhinorrhea; school child; sore throat; South Korea; vaccination | English | 2024 | 2024-06 | 10.6065/apem.2346124.062 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Cohort profile: Multicenter Networks for Ideal Outcomes of Rare Pediatric Endocrine and Metabolic Diseases in Korea (OUTSPREAD study) | Rare endocrine diseases are complex conditions that require lifelong specialized care due to their chronic nature and associated long-term complications. In Korea, a lack of nationwide data on clinical practice and outcomes has limited progress in patient care. Therefore, the Multicenter Networks for Ideal Outcomes of Pediatric Rare Endocrine and Metabolic Disease (OUTSPREAD) study was initiated. This study involves 30 centers across Korea. The study aims to improve the long-term prognosis of Korean patients with rare endocrine diseases by collecting comprehensive clinical data, biospecimens, and patient-reported outcomes to identify complications and unmet needs in patient care. Patients with childhood-onset pituitary, adrenal, or gonadal disorders, such as craniopharyngioma, congenital adrenal hyperplasia (CAH), and Turner syndrome were prioritized. The planned enrollment is 1,300 patients during the first study phase (2022-2024). Clinical, biochemical, and imaging data from diagnosis, treatment, and follow-up during 1980-2023 were retrospectively reviewed. For patients who agreed to participate in the prospective cohort, clinical data and biospecimens will be prospectively collected to discover ideal biomarkers that predict the effectiveness of disease control measures and prognosis. Patient-reported outcomes, including quality of life and depression scales, will be evaluated to assess psychosocial outcomes. Additionally, a substudy on CAH patients will develop a steroid hormone profiling method using liquid chromatography-tandem mass spectrometry to improve diagnosis and monitoring of treatment outcomes. This study will address unmet clinical needs by discovering ideal biomarkers, introducing evidence-based treatment guidelines, and ultimately improving long-term outcomes in the areas of rare endocrine and metabolic diseases. | Lee, Yun Jeong; Cheon, Chong Kun; Suh, Junghwan; Moon, Jung-Eun; Ahn, Moon Bae; Chang, Seong Hwan; Lee, Jieun; Choi, Jin Ho; Kim, Minsun; Lim, Han Hyuk; Kim, Jaehyun; Kim, Shin-Hye; Lee, Hae Sang; Lee, Yena; Kang, Eungu; Kim, Se Young; Hong, Yong Hee; Yang, Seung; Han, Heon-Seok; Chung, Sochung; Cho, Won Kyoung; Kim, Eun Young; Kim, Jin Kyung; Shim, Kye Shik; Yoo, Eun-Gyong; Kim, Hae Soon; Yang, Aram; Kim, Sejin; Nam, Hyo-Kyoung; Cho, Sung Yoon; Lee, Young Ah | Seoul Natl Univ, Childrens Hosp, Dept Pediat, Seoul, South Korea; Pusan Natl Univ, Childrens Hosp, Dept Pediat, Yangsan, South Korea; Pusan Natl Univ, Sch Med, Dept Pediat, Yangsan, South Korea; Yonsei Univ, Coll Med, Dept Pediat, Seoul, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Pediat, Daegu 41404, South Korea; Catholic Univ Korea, Coll Med, Dept Pediat, Seoul, South Korea; Chonnam Natl Univ Hosp, Dept Pediat, Gwangju, South Korea; Inha Univ Hosp, Inha Univ Coll Med, Dept Pediat, 27 Inhang Ro, Incheon 22332, South Korea; Univ Ulsan Coll Med, Dept Pediat, Asan Med Ctr Childrens Hosp, Seoul, South Korea; Jeonbuk Natl Univ, Med Sch, Dept Pediat, Jeonju, South Korea; Chungnam Natl Univ Hosp, Dept Pediat, Daejeon, South Korea; Chonbuk Natl Univ, Biomed Res Inst, Res Inst Clin Med, Chonbuk Natl Univ Hosp, Jeonju, South Korea; Chungnam Natl Univ, Coll Med, Dept Pediat, Daejeon, South Korea; Chungnam Natl Univ, Dept Pediat, Sch Med, Taejon, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Pediat, Seongnam, South Korea; Seoul Natl Univ, Coll Med, Dept Pediat, Seoul 03080, South Korea; Inje Univ, Sanggye Paik Hosp, Dept Pediat, Seoul, South Korea; Ajou Univ, Sch Med, Dept Pediat, Suwon, South Korea; Hallym Univ, Coll Med, Hallym Univ Sacred Heart Hosp, Dept Pediat, Anyang 431070, South Korea; Korea Univ, Ansan Hosp, Dept Pediat, Ansan 425707, Kyunggi, South Korea; Bundang Jesaeng Gen Hosp, Daejin Med Ctr, Dept Pediat, Seongnam 13590, South Korea; Soonchunhyang Univ, Coll Med, Soonchunhyang Univ Bucheon Hosp, Dept Ophthalmol, Bucheon, South Korea; Hanyang Univ, Hanyang Univ Hosp, Coll Med, Dept Pediat, Seoul 04763, South Korea; Chungbuk Natl Univ Hosp, Dept Pediat, Cheongju 28644, South Korea; Konkuk Univ, Med Ctr, Sch Med, Dept Pediat, Seoul, South Korea; Catholic Univ Korea, St Vincents Hosp, Coll Med, Dept Pediat, Seoul, South Korea; Chosun Univ, Chosun Univ Hosp, Coll Med, Dept Neuropsychiat, Gwangju, South Korea; Daegu Catholic Univ, Daegu Catholic Univ Sch Med, Dept Nucl Med, Med Ctr, Daegu 42472, South Korea; Kyung Hee Univ, Kyung Hee Univ Hosp, Sch Med, Dept Pediat, Seoul 02447, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Pediat, Seongnam, South Korea; Ewha Womans Univ, Coll Med, Dept Pediat, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Dept Pediat, Seoul, South Korea; Korea Univ, Guro Hosp, Dept Orthoped Surg, Coll Med, Seoul, South Korea; Korea Univ, Coll Med, Dept Pediat, Seoul, South Korea; Korea Univ, Guro Hosp, Dept Pediat, Seoul 152703, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, 81 Irwan Ro, Seoul 06351, South Korea; Seoul Natl Univ, Childrens Hosp, Dept Pediat, 101 Daehak Ro, Seoul 03080, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, 81 Irwon Ro, Seoul 135710, South Korea | ; Lim, Han Hyuk/AFT-1442-2022; Chung, Sochung/AAU-7950-2020; NAM, HYO-KYOUNG/JTV-1018-2023; Kim, Minsun/ACB-3423-2022; Yoo, Eun-Gyong/IWD-6071-2023; Kim, Shin-Hye/GLS-4405-2022; Kim, YoungHwan/B-2395-2013; Cho, Won-kyoung/AFX-8150-2022; Cheon, Chong Kun/GLU-0305-2022; Kim, Min Sun/K-5771-2013; lee, Hae Sang/AFL-6833-2022 | 57192818370; 26649396100; 57205770806; 57205770947; 56644068400; 59900962800; 56813210000; 56196966800; 57839441000; 36986990700; 56553981800; 36987845400; 56561306600; 57218133973; 57190730666; 55358574700; 36623527300; 54682612000; 35276984600; 8634405100; 54400882600; 57072097200; 36012293800; 36474205800; 7006609222; 55663596500; 57190754058; 57205745876; 56187221000; 57217829002; 35215266500 | nadri1217@naver.com;nina337@snu.ac.kr; | ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | ANN PEDIATR ENDOCRIN | 2287-1012 | 2287-1292 | 29 | 6 | ESCI | ENDOCRINOLOGY & METABOLISM;PEDIATRICS | 2024 | 3.3 | 10.7 | 0 | 2025-05-07 | 0 | 0 | Cohort studies; Treatment outcome; Child; Congenital; adrenal hyperplasia; Craniopharyngioma; Turner; syndrome | QUALITY-OF-LIFE; RELIABILITY; DEFICIENCY; TRANSITION; CARE | Child; Cohort studies; Congenital adrenal hyperplasia; Craniopharyngioma; Endocrine system diseases; Rare disease; Treatment outcome; Turner syndrome | adolescent; anthropometry; Article; Beck Depression Inventory; clinical outcome; cohort analysis; computer assisted tomography; congenital adrenal hyperplasia; craniopharyngioma; depression; echography; endocrine disease; female; follow up; genotype; gonadal disease; human; karyotype; Korea; liquid chromatography-mass spectrometry; major clinical study; metabolic disorder; nuclear magnetic resonance imaging; outcome assessment; patient-reported outcome; Perceived Stress Scale; prognosis; prospective study; quality of life; questionnaire; retrospective study; treatment outcome; Turner syndrome | English | 2024 | 2024-12 | 10.6065/apem.2448272.136 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Continuous and differential improvement in worldwide access to hematopoietic cell transplantation: activity has doubled in a decade with a notable increase in unrelated and non-identical related donors | Promoting access to and excellence in hematopoietic cell transplantation (HCT) by collecting and disseminating data on global HCT activities is one of the principal activities of the Worldwide Network for Blood and Marrow Transplantation, a non-governmental organization in working relations with the World Health Organization. HCT activities are recorded annually by member societies, national registries and individual centers including indication, donor type (allogeneic/autologous), donor match and stem cell source (bone marrow/peripheral blood stem cells/cord blood). In 2018, 1,768 HCT teams in 89 countries (6 World Health Organization regions) reported 93,105 (48,680 autologous and 44,425 allogeneic) HCT. Major indications were plasma cell disorders and lymphoma for autologous, and acute leukemias and MDS/MPN for allogeneic HCT. HCT numbers increased from 48,709 in 2007. Notable increases were seen for autoimmune diseases in autologous and hemoglobinopathies in allogeneic HCT. The number of allogeneic HCT more than doubled with significant changes in donor match. While HCT from HLA-identical siblings has seen only limited growth, HCT from non-identical related donors showed significant increase worldwide. Strongest correlation between economic growth indicator of gross national income/capita and HCT activity/10 million population was observed for autologous HCT (correlation coefficient [r]=0.79). HCT from unrelated donors showed strong correlation (r=0.68), but only moderate correlation was detected from related donors (r=0.48 for HLA-identical sibling; r=0.45 for other). The use of HCT doubled in about a decade worldwide at different speed and with significant changes regarding donor match as a sign of improved access to HCT worldwide. Although narrowing, significant gaps remain between developing and non-developing countries. | Atsuta, Yoshiko; Baldomero, Helen; Neumann, Daniel; Sureda, Anna; DeVos, Jakob D.; Iida, Minako; Karduss, Amado; Purtill, Duncan; Elhaddad, Alaa M.; Bazuaye, Nosa G.; Bonfim, Carmem; de la Camara, Rafael; Chaudhri, Naeem A.; Ciceri, Fabio; Correa, Cinthya; Frutos, Cristobal; Galeano, Sebastian; Garderet, Laurent; Gonzalez-Ramella, Oscar; Greco, Raffaella; Hamad, Nada; Hazenberg, Mette D.; Horowitz, Mary M.; Kalwak, Krzysztof; Ko, Bor-Sheng; Kodera, Yoshihisa; Koh, Mickey B. C.; Liu, Kaiyan; McLornan, Donal P.; Moon, Joon Ho; Neven, Benedicte; Okamoto, Shinichiro; Pasquini, Marcelo C.; Passweg, Jakob R.; Paulson, Kristjan; Rondelli, Damiano; Ruggeri, Annalisa; Seber, Adriana; Snowden, John A.; Srivastava, Alok; Szer, Jeff; Weisdorf, Daniel; Worel, Nina; Greinix, Hildegard; Saber, Wael; Aljurf, Mahmoud; Niederwieser, Dietger | Japanese Data Ctr Hematopoiet Cell Transplantat, Nagakute, Japan; Aichi Med Univ, Sch Med, Dept Registry Sci Transplant & Cellular Therapy, Nagakute, Japan; Univ Hosp, Worldwide Network Blood & Marrow Transplantat WBMT, Transplant Act Survey Off, Basel, Switzerland; Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany; Univ Barcelona, Inst Catala Oncol LHospitalet, Clin Hematol Dept, IDIBELL, Barcelona, Spain; Med Coll Wisconsin, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI USA; Aichi Med Univ, Sch Med, Dept Promot Blood & Marrow Transplantat, Nagakute, Japan; Inst Cancerol Clin Las Amer, Medellin, Colombia; Fiona Stanley Hosp, Hematol Dept, Perth, WA, Australia; Cairo Univ, Dept Pediat Oncol, Cairo, Egypt; Cairo Univ, Stem Cell Transplantat Unit, Cairo, Egypt; Univ Benin, Dept Hematol & Blood Transfus, Teaching Hosp, Benin, Edo State, Nigeria; Hosp Pequeno Principe, Pele Pequeno Principe Res Inst, Pediat Blood & Marrow Transplantat Program, Curitiba, Brazil; Hosp Princesa, Hematol Dept, Madrid, Spain; King Faisal Specialist Hosp & Res Ctr, Oncol Ctr, Riyadh, Saudi Arabia; Osped San Raffaele srl, Hematol & BMT, Milan, Italy; Hosp Israelita Albert Einstein, Sao Paulo, Brazil; Inst Previs Social, Asuncion, Paraguay; Hosp Britanico, Montevideo, Uruguay; Sorbonne Univ, Hop Pitie Salpetriere, AP HP, Serv Hematol & Therapie Cellulaire, Paris, France; Hosp Civil Guadalajara, Dr Juan I Menchaca, Guadalajara, Mexico; IRCCS San Raffaele Hosp, Unit Hematol & Bone Marrow Transplantat, Milan, Italy; Kinghorn Canc Ctr, Hematol Clin Res Unit, St Vincents Hlth Network, Sydney, NSW, Australia; Univ Amsterdam, Amsterdam Univ, Locat Acad Med Ctr, Dept Hematol,Med Ctr, Amsterdam, Netherlands; Wroclaw Med Univ, Dept Pediat Hematol Oncol & BMT, Wroclaw, Poland; Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan; Univ London, St Georges Hosp & Med Sch, Inst Infect & Immun, London, England; Peking Univ, Inst Hematol, Dept Hematol, Beijing, Peoples R China; Univ Coll Hosp, Dept Hematol, London, England; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Hematol Oncol, Daegu, South Korea; Hop Necker Enfants Malad, Assistance Publ Hop Paris, Serv Immunol Hematol & Rhumatol Pediat, INSERM, Paris, France; Keio Univ, Sch Med, Dept Med, Div Hematol, Tokyo, Japan; Univ Manitoba, Max Rady Coll Med, Dept Internal Med, Sect Hematol Oncol, Winnipeg, MB, Canada; Univ Illinois, Div Hematol Oncol, Chicago, IL USA; Ist Sci San Raffaele, Hematol & BMT Unit, Milan, Italy; Univ Fed Sao Paulo, Escola Paulista Med, Dept Med, Sao Paulo, Brazil; Sheffield Teaching Hosp NHS Fdn Trust, Dept Hematol, Sheffield, England; Christian Med Coll & Hosp, Dept Hematol, Vellore, India; Clin Hematol Peter MacCallum Canc Ctr, Melbourne, Vic, Australia; Royal Melbourne Hosp, Melbourne, Vic, Australia; Univ Minnesota, Dept Med, Div Hematol Oncol & Transplantat, Minneapolis, MN USA; Med Univ Vienna, Dept Transfus Med & Cell Therapy, Vienna, Austria; Med Univ Graz, Div Hematol, Graz, Austria; Univ Leipzig, Leipzig, Germany | ; CICERI, Fabio/LSJ-5748-2024; neven, benedicte/C-8676-2015; Neumann, Daniel/HRB-5022-2023; Greco, Raffaella/K-9499-2016; Ko, Bor-Sheng/AAC-6659-2021; passweg, jakob/AAG-3911-2020; Hamad, Nada/AAR-9461-2020; Gonzalez-Ramella, Oscar/ABF-2695-2020; Garderet, laurent/ADT-2311-2022; Seber, Adriana/AAG-7978-2020; de la Camara, Rafael/B-2106-2009; Neven, Benedicte/ADZ-2440-2022; Kalwak, Krzysztof/U-1724-2019 | 57993918500; 6603955293; 57893056500; 56148330700; 58544902600; 7402238077; 11241298800; 35750618000; 59227712400; 56152942600; 8504188600; 7003537558; 16229539800; 57219034470; 57201659728; 57216394993; 54931613400; 55967797700; 58925146100; 55340915800; 56048203200; 7007014812; 7401750010; 55916637100; 35210620900; 35378498800; 7103400013; 35322930900; 13907176100; 56568642700; 6508178857; 57216567098; 11939970800; 35243190200; 57185256400; 7003358830; 8603207300; 6506892615; 7005452706; 57211730392; 7006053620; 57220727831; 6701602820; 7005936353; 23976412000; 55863021500; 35374989800 | y-atsuta@jdchct.or.jp; | HAEMATOLOGICA | HAEMATOLOGICA | 0390-6078 | 1592-8721 | 109 | 10 | SCIE | HEMATOLOGY | 2024 | 7.9 | 10.7 | 1.86 | 2025-05-07 | 8 | 8 | MARROW-TRANSPLANTATION; POSTTRANSPLANT CYCLOPHOSPHAMIDE; HEMATOLOGIC MALIGNANCIES; BLOOD; OUTCOMES; MORTALITY; SURVIVAL; DISEASE; ADULTS | Global Health; Health Services Accessibility; Hematopoietic Stem Cell Transplantation; Humans; Registries; Tissue Donors; Unrelated Donors; acute leukemia; acute lymphoblastic leukemia; acute myeloid leukemia; Article; autoimmune disease; bone marrow depression; bone marrow transplantation; chronic lymphatic leukemia; chronic myeloid leukemia; cord blood stem cell transplantation; gross national income; hematopoietic stem cell transplantation; hemoglobinopathy; human; major clinical study; myelodysplastic syndrome; myeloproliferative neoplasm; observational study; peripheral blood stem cell; retrospective study; donor; global health; health care access; procedures; register; unrelated donor | English | 2024 | 2024-10 | 10.3324/haematol.2024.285002 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Effectiveness and Safety of Ustekinumab in Pediatric Ulcerative Colitis: A Multi-center Retrospective Study from the Pediatric IBD Porto Group of ESPGHAN | Background and Objectives Current data on ustekinumab therapy in children with ulcerative colitis (UC) or unclassified inflammatory bowel disease (IBDU) are limited. We aimed to evaluate the effectiveness and safety of ustekinumab in pediatric UC and IBDU. Methods This multicenter retrospective study included 16 centers affiliated with the IBD Interest and Porto groups of ESPGHAN. Children with UC or IBDU treated with ustekinumab were enrolled. Demographic, clinical, laboratory, endoscopic, and imaging data as well as adverse events were recorded. Analyses were all based on the intention-to-treat principle. Results Fifty-eight children (39 UC and 19 IBDU, median age 14.5 [IQR 11.5-16.5] years) were included. All had failed biologic therapies, and 38 (66%) had failed two or more biologics. Corticosteroid-free clinical remission (CFR) was observed in 27 (47%), 33 (57%), and 37 (64%) children at 16, 26, and 52 weeks, respectively. Normalization of C-reactive protein and calprotectin < 150 mu g/g were achieved in 60% and 52%, respectively, by 52 weeks. Endoscopic and radiologic remissions were reached in 8% and 23%, respectively. The main predictors of CFR were diagnosis of UC compared with IBDU (hazard ratio [HR] 2.2, 95% CI 1.03-4.85; p = 0.041) and no prior vedolizumab therapy (HR 2.1, 95% CI 1.11-4.27; p = 0.023). Ustekinumab serum levels were not associated with disease activity. Adverse events were recorded in six (10%) children, leading to discontinuation of the drug in three. Conclusion Based on these findings, ustekinumab appears as an effective therapy for pediatric refractory UC and IBDU. The potential efficacy should be weighed against the risks of serious adverse events. | Cohen, Shlomi; Rolandsdotter, Helena; Kolho, Kaija-Leena; Turner, Dan; Tzivinikos, Christos; Bramuzzo, Matteo; Pujol-Muncunill, Gemma; Scarallo, Luca; Urlep, Darja; Rinawi, Firas; Granot, Maya; Kang, Ben; Longueville, Ylva; Rodriguez-Belvis, Marta Velasco; Weintraub, Yael; Navas-Lopez, Victor Manuel; Yerushalmy-Feler, Anat | Tel Aviv Univ, Pediat Gastroenterol Inst, Dana Dwek Childrens Hosp, Tel Aviv Sourasky Med Ctr, 6 Weizmann St, IL-6423906 Tel Aviv, Israel; Tel Aviv Univ, Fac Med, 6 Weizmann St, IL-6423906 Tel Aviv, Israel; Sachs Children & Youth Hosp, Dept Clin Sci & Educ, Stockholm, Sweden; Sachs Children & Youth Hosp, Karolinska Inst, Dept Gastroenterol, Stockholm, Sweden; Sachs Children & Youth Hosp, Dept Gastroenterol, Stockholm, Sweden; Univ Helsinki, Childrens Hosp, Dept Paediat Gastroenterol, Helsinki, Finland; Univ Helsinki, Tampere Univ, HUS, Helsinki, Finland; Univ Helsinki, Helsinki, Finland; Tampere Univ, Tampere, Finland; Hebrew Univ Jerusalem, Shaare Zedek Med Ctr, Eisenberg R&D Author, Juliet Keiden Inst Pediat Gastroenterol & Nutr, Jerusalem, Israel; Mohammed Bin Rashid Univ Med & Hlth Sci, Al Jalila Childrens Specialty Hosp, Dept Pediat Gastroenterol, Dubai, U Arab Emirates; IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Gastroenterol Digest Endoscopy & Nutr Unit, Trieste, Italy; Hosp San Juan Dios, Dept Pediat Gastroenterol Hepatol & Nutr, Barcelona, Spain; Meyer Childrens Hosp, IRCCS, Gastroenterol & Nutr Unit, Florence, Italy; Univ Childrens Hosp Ljubljana, Dept Gastroenterol Hepatol & Nutr, Ljubljana 1000, Slovenia; Pediat Gastroenterol Unit, Afula, Israel; Emek Med Ctr, Fac Med Technion, Afula, Israel; Fac Med Technion, Haifa, Israel; Tel Aviv Univ, Pediat Gastroenterol & Nutr Unit, Edmond & Lily Safra Childrens Hosp, Ramat Gan, Israel; Tel Aviv Univ, Fac Med, Sheba Med Ctr, Ramat Gan, Israel; Tel Aviv Univ, Fac Med, Tel Aviv, Israel; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Karolinska Univ Hosp, Pediat Gastroenterol Unit, Stockholm, Sweden; Hosp Infantil Univ Nino Jesus, Paediat Gastroenterol Hepatol & Nutr, Madrid, Spain; Tel Aviv Univ, Schneider Childrens Med Ctr, Tel Aviv, Israel; Tel Aviv Univ, Inst Gastroenterol Nutr & Liver Dis, Fac Med, Tel Aviv, Israel; Hosp Reg Univ Malaga, Pediat Gastroenterol & Nutr Unit, Malaga, Spain | Rolandsdotter, Helena/J-5146-2019; Scarallo, Luca/AAQ-9438-2020; Bramuzzo, Matteo/K-2504-2018; 康, 奔/JMQ-0812-2023 | 36808812900; 57193544549; 6701638121; 57198448551; 56230811200; 33067537800; 55959633100; 57204424323; 8964706700; 56262375400; 57204356090; 57194823199; 59139222200; 7201355120; 55216325300; 6508256680; 56016081800 | shlomico@tlvmc.gov.il; | PEDIATRIC DRUGS | PEDIATR DRUGS | 1174-5878 | 1179-2019 | 26 | 5 | SCIE | PEDIATRICS;PHARMACOLOGY & PHARMACY | 2024 | 3.3 | 10.7 | 5.72 | 2025-05-07 | 7 | 7 | INFLAMMATORY-BOWEL-DISEASE; MAINTENANCE THERAPY; INDUCTION; CHILDREN; MODERATE | Adolescent; Child; Colitis, Ulcerative; Female; Humans; Male; Pediatric ulcerative colitis; Remission Induction; Retrospective Studies; Treatment Outcome; Ustekinumab; acetylsalicylic acid; adalimumab; aminosalicylic acid; antibiotic agent; azathioprine; biological product; C reactive protein; calgranulin; corticosteroid; cyclosporine; etrolizumab; golimumab; hemoglobin; infliximab; mercaptopurine; methotrexate; tacrolimus; thalidomide; tofacitinib; ustekinumab; vedolizumab; ustekinumab; acute diarrhea; adolescent; Article; breast abscess; child; cohort analysis; controlled study; cytomegalovirus infection; disease exacerbation; drug dose escalation; drug efficacy; drug safety; drug withdrawal; enteric feeding; erythrocyte sedimentation rate; female; follow up; hemoglobin blood level; human; human tissue; hypersensitivity; injection site reaction; intention to treat analysis; interstitial nephritis; longitudinal study; major clinical study; male; multicenter study (topic); outcome assessment; phenotype; remission; retrospective study; school child; ulcerative colitis; clinical trial; drug therapy; multicenter study; treatment outcome; ulcerative colitis | English | 2024 | 2024-09 | 10.1007/s40272-024-00631-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Glutamic-Alanine Rich Glycoprotein from Undaria pinnatifida: A Promising Natural Anti-Inflammatory Agent | This study aimed to assess the anti-inflammatory properties of a bioactive glutamic-alanine rich glycoprotein (GP) derived from Undaria pinnatifida on both LPS-stimulated RAW264.7 cells, peritoneal macrophages, and mouse models of carrageenan- and xylene-induced inflammation, investigating the underlying molecular mechanisms. In both in-vitro and in-vivo settings, GP was found to reduce the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) while also inhibiting the production of nitric oxide (NO) and prostaglandin E-2 (PGE(2)) in response to lipopolysaccharide (LPS) stimulation. GP treatment significantly impeded the nuclear translocation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappa B) pathway by blocking the phosphorylation of IKK alpha and I kappa B alpha, leading to a reduction in proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta), and interleukin-6 (IL-6). Additionally, GP effectively inhibited the activation of mitogen-activated protein kinases (MAPKs), with specific inhibitors of p38 and extra-cellular signal regulated kinase (ERK) enhancing GP's anti-inflammatory efficacy. Notably, GP administration at 10 mg/kg/day (p.o.) markedly reduced carrageenan-induced paw inflammation and xylene-induced ear edema by preventing the infiltration of inflammatory cells into targeted tissues. GP treatment also downregulated key inflammatory markers, including iNOS, COX-2, I kappa B alpha, and NF-kappa B, by suppressing the phosphorylation of p38 and ERK, thereby improving the inflammatory index in both carrageenan- and xylene-induced mouse models. These findings suggest that marine resources, particularly seaweeds like U. pinnatifida, could serve as valuable sources of natural anti-inflammatory proteins for the effective treatment of inflammation and related conditions. | Rahman, Md Saifur; Alam, Md Badrul; Naznin, Marufa; Madina, Mst Hur; Rafiquzzaman, S. M. | Laval Univ, Inst Nutr & Funct Foods INAF, Fac Agr & Food Sci, Quebec City, PQ G1V 0A6, Canada; Kyungpook Natl Univ, Food & Bioind Res Inst, Inner Beauty Antiaging Ctr, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Chem Educ, Daegu 41566, South Korea; Bangabandhu Sheikh Mujibur Rahman Agr Univ, Dept Fisheries Biol & Aquat Environm, Gazipur 1706, Bangladesh | Alam, Md Badrul/AFL-7668-2022; Rahman, Md Saifur/KBB-4577-2024 | 57192805985; 56706777100; 57195955389; 57203279223; 55915530200 | md-saifur.rahman.1@ulaval.ca;mbalam@knu.ac.kr;naznin@knu.ac.kr;mosammad-hur.madina.1@ulaval.ca;rafiquzzaman@bsmrau.edu.bd; | MARINE DRUGS | MAR DRUGS | 1660-3397 | 22 | 9 | SCIE | CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY | 2024 | 5.4 | 10.7 | 0.7 | 2025-05-07 | 1 | 1 | anti-inflammation; glycoprotein; NF-kappa B; Undaria pinnatifida; MAPK; NSAID | IN-VITRO; POLARIZATION; INFLAMMATION; ANTIOXIDANT; SEAWEED; PATHWAY | anti-inflammation; glycoprotein; MAPK; NF-κB; NSAID; Undaria pinnatifida | Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Edema; Edible Seaweeds; Glycoproteins; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Undaria; Undaria pinnatifida; Xylenes; alanine; antiinflammatory agent; beta actin; carrageenan; cyclooxygenase 2; glutamic acid; glycoprotein; immunoglobulin enhancer binding protein; inducible nitric oxide synthase; interleukin 1beta; interleukin 6; lipopolysaccharide; messenger RNA; mitogen activated protein kinase; nitric oxide synthase; synaptophysin; tumor necrosis factor; xylene; antiinflammatory agent; cyclooxygenase 2; cytokine; glycoprotein; immunoglobulin enhancer binding protein; inducible nitric oxide synthase; lipopolysaccharide; nitric oxide; prostaglandin E2; xylene; animal experiment; animal model; animal tissue; antiinflammatory activity; Article; cell viability; controlled study; cytokine release; cytotoxicity; ear edema; enzyme linked immunosorbent assay; histology; human; human cell; immune response; macrophage; male; MAPK signaling; mouse; MTT assay; nonhuman; paw edema; protein expression; protein phosphorylation; RAW 264.7 cell line; Undaria pinnatifida; Western blotting; animal; chemistry; disease model; drug effect; drug therapy; edema; edible seaweed; inflammation; metabolism; peritoneum macrophage; RAW 264.7 cell line; Undaria; Undaria pinnatifida | English | 2024 | 2024-09 | 10.3390/md22090383 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Inhibition of Soluble Epoxide Hydrolase by Cembranoid Diterpenes from Soft Coral Sinularia maxima: Enzyme Kinetics, Molecular Docking, and Molecular Dynamics | Soluble epoxide hydrolase (sEH) is essential for converting epoxy fatty acids, such as epoxyeicosatrienoic acids (EETs), into their dihydroxy forms. EETs play a crucial role in regulating blood pressure, mediating anti-inflammatory responses, and modulating pain, making sEH a key target for therapeutic interventions. Current research is increasingly focused on identifying sEH inhibitors from natural sources, particularly marine environments, which are rich in bioactive compounds due to their unique metabolic adaptations. In this study, the sEH inhibitory activities of ten cembranoid diterpenes (1-10) isolated from the soft coral Sinularia maxima were evaluated. Among them, compounds 3 and 9 exhibited considerable sEH inhibition, with IC50 values of 70.68 mu M and 78.83 mu M, respectively. Enzyme kinetics analysis revealed that these two active compounds inhibit sEH through a non-competitive mode. Additionally, in silico approaches, including molecular docking and molecular dynamics simulations, confirmed their stability and interactions with sEH, highlighting their potential as natural therapeutic agents for managing cardiovascular and inflammatory diseases. | Phong, Nguyen Viet; Thao, Nguyen Phuong; Vinh, Le Ba; Luyen, Bui Thi Thuy; Minh, Chau Van; Yang, Seo Young | Kyungpook Natl Univ, Teachers Coll, Dept Biol Educ, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Phylogen & Evolut, Daegu 41566, South Korea; Vietnam Acad Sci & Technol VAST, Inst Marine Biochem, 18 Hoang Quoc Viet, Hanoi 10072, Vietnam; Hanoi Univ Pharm, Fac Pharmaceut Chem & Technol, 13-15 Thanh Tong, Hanoi 11021, Vietnam | Nguyen, Viet Phong/AAQ-4207-2021; NGUYEN, Phan/HGU-2477-2022; Le, Vinh/AAK-7699-2021 | 57205196739; 35761744300; 57190582257; 54401548100; 6602070625; 57215036954 | ngvietphong@gmail.com;thaonp@imbc.vast.vn;vinhrooney@gmail.com;luyenbthoaduoc@gmail.com;cvminh@vast.vn;syy@knu.ac.kr; | MARINE DRUGS | MAR DRUGS | 1660-3397 | 22 | 8 | SCIE | CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY | 2024 | 5.4 | 10.7 | 2.09 | 2025-05-07 | 3 | 3 | Sinularia maxima; cembranoid diterpenes; soluble epoxide hydrolase; molecular docking; molecular dynamics | SEH INHIBITORS; EXPRESSION; DISCOVERY | cembranoid diterpenes; molecular docking; molecular dynamics; Sinularia maxima; soluble epoxide hydrolase | Animals; Anthozoa; Diterpenes; Enzyme Inhibitors; Epoxide Hydrolases; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; cembranoid; diterpenoid; enzyme inhibitor; epoxide hydrolase; epoxyicosatrienoic acid; hydrolase inhibitor; recombinant protein; diterpenoid; enzyme inhibitor; allosterism; amino acid sequence; antiinflammatory activity; Article; binding affinity; binding site; cardiovascular disease; chemical structure; computer model; coral; cytotoxicity; density functional theory; drug interaction; drug stability; drug structure; enzyme active site; enzyme inhibition; enzyme inhibition assay; enzyme kinetics; fluorescence; hydrogen bond; hydrophobicity; IC50; inflammation; marine environment; metabolism; molecular docking; molecular dynamics; nonhuman; protein structure; simulation; Sinularia maxima; animal; Anthozoa; chemistry; isolation and purification; kinetics | English | 2024 | 2024-08 | 10.3390/md22080373 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Introducing graupel density prediction in Weather Research and Forecasting (WRF) double-moment 6-class (WDM6) microphysics and evaluation of the modified scheme during the ICE-POP field campaign | The Weather Research and Forecasting (WRF) double-moment 6-class (WDM6) scheme was modified by incorporating predicted graupel density. Explicitly predicted graupel density, in turn, modifies graupel characteristics such as the fall velocity-diameter and mass-diameter relationships of graupel. The modified WDM6 has been evaluated based on a two-dimensional (2D) idealized squall line simulation and winter snowfall events that occurred during the International Collaborative Experiment for Pyeongchang Olympics and Paralympics (ICE-POP 2018) field campaign over the Korean Peninsula. From the 2D simulation, we confirmed that the modified WDM6 can simulate varying graupel densities, ranging from low values in an anvil cloud region to high values in the convective region at the mature stage of a squall line. Simulations with the modified WDM6 increased graupel amounts at the surface and decreased graupel aloft because of the faster sedimentation of graupel for two winter snowfall cases during the ICE-POP 2018 campaign, as simulated in the 2D idealized model. The altered graupel sedimentation in the modified WDM6 influenced the magnitude of the major microphysical processes of graupel and snow, subsequently reducing the surface snow amount and precipitation over the mountainous region. The reduced surface precipitation over the mountainous region mitigates the surface precipitation bias observed in the original WDM6, resulting in better statistical skill scores for the root mean square errors. Notably, the modified WDM6 reasonably captures the relationship between graupel density and its fall velocity, as retrieved from 2D video disdrometer measurements, thus emphasizing the necessity of including predicted graupel density to realistically represent the microphysical properties of graupel in models. | Park, Sun-Young; Lim, Kyo-Sun Sunny; Kim, Kwonil; Lee, Gyuwon; Milbrandt, Jason A. | Kyungpook Natl Univ, Ctr Atmospher Remote Sensing, Dept Atmospher Sci, Weather Extremes Educ & Res Team BK21, Daegu, South Korea; SUNY Stony Brook, Sch Marine & Atmospher Sci, Stony Brook, NY USA; Environm & Climate Change Canada, Atmospher Numer Weather Predict Res, Dorval, PQ, Canada | Lim, Kyo-Sun/I-3811-2012; Kim, Kwonil/HTN-0103-2023 | 58111297900; 57211926026; 57191964318; 7404852271; 9239331500 | kyosunlim@knu.ac.kr; | GEOSCIENTIFIC MODEL DEVELOPMENT | GEOSCI MODEL DEV | 1991-959X | 1991-9603 | 17 | 18 | SCIE | GEOSCIENCES, MULTIDISCIPLINARY | 2024 | 4.9 | 10.7 | 0 | 2025-05-07 | 1 | 1 | SIMULATED SQUALL LINE; CLOUD MICROPHYSICS; PART I; TERMINAL VELOCITIES; CONVECTIVE CLOUDS; WINTER STORMS; POWER LAWS; BULK; PARAMETERIZATION; PRECIPITATION | experimental study; mountain region; precipitation (climatology); prediction; snow cover; two-dimensional modeling; weather forecasting | English | 2024 | 2024-09-27 | 10.5194/gmd-17-7199-2024 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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