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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Selective recovery of caprolactam from the thermo-catalytic conversion of textile waste over γ-Al2O3 supported metal catalysts | The massive generation of synthetic textile waste has drawn considerable attention. Landfilling/incineration of textile waste has been widely made. To abate the environmental burdensome from the conventional management processes, a thermo-catalytic conversion was used for rapid volume reduction of textile waste and simultaneous valorization by recovering textile monomer in this study. Stockings were chosen as a model feedstock. Because stockings consisted of nylon with other contents, different products (caprolactam (nylon monomer), imines, cyclic dimers, and azepines) were recovered. The yield of caprolactam from the thermal conversion at 500 degrees C was 53.6 wt%. To selectively enhance the caprolactam yield, catalytic pyrolysis was done using gamma-Al2O3 supported metal catalysts (Ni, Cu, Fe, or Co). gamma-Al2O3 itself increased the caprolactam yield up to 69.0 wt% via a based -catalyzed reaction of nylon depolymerization and intramolecular cyclization. Under the presence of metal cat-alysts, the caprolactam yield increased up to 73.3 wt%. To offer desired feature of green chemistry, CO2 was adopted as reactive gas. Under the CO2-mediated catalytic pyrolysis, caprolactam yield was enhanced up to 77.1 wt% over Cu/Al2O3 (basis: stocking mass). Based on the net content of nylon in the stockings, the yield of caprolactam was deemed 95.3 wt%. This study proves that textile waste (stocking) and CO2 are useful resources for recovery of nylon monomer, which can reduce the waste generation with simultaneous recovery of value-added product. | Yang, Wooyoung; Jung, Sungyup; Lee, Jechan; Lee, Sung Woo; Kim, Yong Tae; Kwon, Eilhann E. | Sungkyunkwan Univ, Dept Global Smart City, 2066 Seobu Ro, Suwon 16419, South Korea; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Sungkyunkwan Univ, Sch Civil Architectural Engn & Landscape Architect, 2066 Seobu Ro, Suwon 16419, South Korea; Korea Res Inst Chem Technol, Chem & Proc Technol Div, 141 Gajeong Ro, Daejeon 34114, South Korea; Hanyang Univ, Dept Earth Resources & Environm Engn, 222 Wangsimni Ro, Seoul 04763, South Korea | Jung, Sungyup/ABE-1493-2021; Kim, Yong Tae/CKE-7709-2022; Kwon, Eilhann/AGY-3339-2022; Lee, Jechan/J-1229-2016 | 57863490200; 55073290800; 57188712886; 57208718846; 57214231910; 9240622100 | ek2148@hanyang.ac.kr; | ENVIRONMENTAL POLLUTION | ENVIRON POLLUT | 0269-7491 | 1873-6424 | 329 | SCIE | ENVIRONMENTAL SCIENCES | 2023 | 7.6 | 10.2 | 2.42 | 2025-06-25 | 19 | 20 | Circular economy; Waste valorization; Synthetic textile; Nylon; Caprolactam; Pyrolysis | STOCKINGS; PLASTICS; WATER | Caprolactam; Circular economy; Nylon; Pyrolysis; Synthetic textile; Waste valorization | Caprolactam; Carbon Dioxide; Catalysis; Metals; Nylons; Textiles; Alumina; Aluminum oxide; Carbon dioxide; Catalyst supports; Copper compounds; Cyclization; Polyamides; Pyrolysis; Rayon; Recycling; Textiles; Wastes; aluminum oxide; azepine derivative; caprolactam; copper; gamma alumina; imine; iron; monomer; nickel; nylon; unclassified drug; caprolactam; carbon dioxide; metal; nylon; Caprolactam; Catalytic conversion; Catalytic pyrolysis; Circular economy; Landfilling; Management process; Nylon; Selective recovery; Supported-metal catalysts; Waste valorizations; catalyst; pyrolysis; textile industry; valorization; waste treatment; Article; catalysis; catalyst; chemical structure; cyclization; depolymerization; flame ionization detection; gas chromatography; gasification; green chemistry; industrial waste; mass fragmentography; melting point; metal recovery; nonhuman; pyrolysis; textile industry; thermogravimetry; valorization; waste valorization; catalysis; Synthetic textile fibers | English | 2023 | 2023-07-15 | 10.1016/j.envpol.2023.121684 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Transformational leadership, integration and supply chain risk management in Vietnam's manufacturing firms | Purpose Due to an increase in vulnerability, supply chain risk management (SCRM) has gained the attention of both researchers and practitioners. Although different approaches have been widely used to discuss the implementation of risk management, the impacts of leadership factors on SCRM have received little attention. To fill this gap in the literature, this study aims to examine whether transformational leadership and integration facilitate SCRM and enhance performance. Design/methodology/approach Using 261 Vietnamese manufacturing companies as sample, this study applies partial least squares based structural equation modeling (SEM) to test the proposed hypotheses. Findings This study demonstrates three contributions for exist leadership and supply chain literature. First, the characteristics of transformational leadership effectively facilitate the internal and external integration in supply chain with higher responsiveness, visibility and integration. Second, transformational leadership has indirectly effect to supply chain risk management practice (SCRMP) throughout supply chain integration (SCI). Additionally, three dimensions of integration enable SCRM and partially mediate the relationship between transformational leadership and SCRM. Furthermore, SCRM not only plays a partially mediating role in the relationship between internal integration, customer integration and supply chain performance but also fully mediates the relationship between supplier integration and supply chain performance. Practical implications This study addresses that the paper extends the content of the relationship between transformational leadership and SCI by three integration dimensions among of exist literature. Transformational leadership should be literarily included into part of leadership strategy on SCRMPs since it is shown to have an indirectly positive improvement effect on SCRM. In addition, the paper is targeted the supply chain downstream performance (SCDP) with integration and risk management with the concept of considering downstream performance is a key section to confront the external stakeholder and customers, Finally, the authors emphasized companies should be aware of the importance about how to include transformational leadership, SCI and SCRMP into its supply chain management. Originality/value This study contributes to the SCRM literature by empirically examining the effect of transformational leadership and SCI on SCRM and performance in Vietnam, which is few and far better than that of developed countries. | Phung, Thi Bich Phuong; Kim, Sungsu; Chu, Chia Chia | Kyungpook Natl Univ, Sch Business Adm, Daegu, South Korea | 57680041300; 57835384100; 57678215900 | sungsukim@knu.ac.kr; | INTERNATIONAL JOURNAL OF LOGISTICS MANAGEMENT | INT J LOGIST MANAG | 0957-4093 | 1758-6550 | 34 | 1 | SSCI | MANAGEMENT | 2023 | 7.2 | 10.2 | 1.45 | 2025-06-25 | 12 | 13 | Transformational leadership; Supply chain integration; Supply chain risk management; Supply chain performance; Vietnam | PERFORMANCE; IMPACT; IMPLEMENTATION; CAPABILITIES; DISRUPTIONS; FRAMEWORK; QUALITY; BIASES | Supply chain integration; Supply chain risk management; Supply chain performance; Transformational leadership; Vietnam | English | 2023 | 2023-01-18 | 10.1108/ijlm-06-2021-0317 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | A review of membrane-based dewatering technology for the concentration of liquid foods | The imperative to establish environmentally friendly and sustainable food processing techniques has compelled the food industry to explore alternative approaches that uphold food quality, ensure nutritional integrity, and minimize energy consumption. Extensive research conducted in the past decade has substantiated the superiority of membrane-based dewatering technology over conventional methods, owing to its ability to retain nutrients effectively while minimizing energy requirements. Notably, forward osmosis (FO) and membrane distillation (MD) have emerged as viable membrane technologies for food processing in the industry. However, recent reviews have underscored the prominence of FO in the enrichment of liquid food, positioning it as a preferred choice among other membrane-based processes. This review paper aims to elucidate the advancements and contributions of FO and MD in the realm of food processing while evaluating their maturity and technology readiness level for food concentration. Moreover, it endeavors to delineate specific parameters, including pretreatment techniques, membrane cleaning strategies, and membrane configurations/modules tailored to liquid food sources' distinct dewatering requirements. Although most FO and MD studies have focused on lab-scale fruit juice and whey concentration, future investigations should encompass pilot-scale process development alongside comprehensive techno-economic analyses to facilitate the smooth transition of these technologies to an industrial scale. | Gulied, Mona; Logade, Khulood; Mutahir, Hafsa; Shaftah, Sadiyah; Salauddin, Sayma; Hameed, Areeba; Zavahir, Sifani; Elmakki, Tasneem; Shon, Ho Kyong; Hong, Seungkwan; Park, Hyunwoong; Han, Dong Suk | Qatar Univ, Ctr Adv Mat, POB 2713, Doha, Qatar; Qatar Univ, Dept Chem Engn, POB 2713, Doha, Qatar; Qatar Univ, Coll Arts & Sci, Mat Sci & Technol Master Program, POB 2713, Doha, Qatar; Univ Technol Sydney, Ctr Technol Water & Wastewater, Sch Civil & Environm Engn, Sydney, NSW 2007, Australia; Korea Univ, Sch Civil Environm & Architectural Engn, Seoul 02841, South Korea; Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea | Han, Dong SuK/AAX-9333-2021; Shon, Ho Kyong/P-7057-2015; Kim, Jungbin/Y-6640-2018; Shon, Ho/P-7057-2015 | 57204041429; 57389216900; 57218205427; 58509810000; 57389716400; 57389882900; 56493120500; 57221280532; 6701629946; 10144928600; 7601565583; 36139213900 | dhan@qu.edu.qa; | JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING | J ENVIRON CHEM ENG | 2213-2929 | 2213-3437 | 11 | 5 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2023 | 7.4 | 10.3 | 0.35 | 2025-06-25 | 10 | 12 | Food processing; Food security; Forward osmosis; Membrane distillation; Technology readiness level | BLACK-CURRANT JUICE; SUGARCANE JUICE; FOULING CONTROL; WATER RECOVERY; HYBRID SYSTEM; FRUIT JUICE; OSMOSIS; WHEY; DISTILLATION; ENERGY | Food processing; Food security; Forward osmosis; Membrane distillation; Technology readiness level | Dewatering; Distillation; Economic analysis; Energy utilization; Food supply; Fruit juices; Membrane technology; Osmosis; Processed foods; Concentration of liquid food; Food industries; Food quality; Food security; Forward osmosis; Liquid food; Membrane distillation; Membrane-based; Processing technique; Technology readiness levels; Food processing | English | 2023 | 2023-10 | 10.1016/j.jece.2023.110583 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Electrochemical system design for CO2 conversion: A comprehensive review | This paper reviews the electrochemical reduction of CO2 and the design of CO2 electrolyzer cells using advanced materials and novel configurations to improve efficiency and reduce costs. It examines various system types based on geometry and components, analyzing key performance parameters to offer valuable insights into effective and selective CO2 conversion. Techno-economic analysis is employed to assess the commercial viability of electrochemical CO2 reduction (eCO2R) products. Additionally, the paper discusses the design of eCO2R re-actors, addressing challenges, benefits, and developments associated with reactant supply in liquid and gas phases. It also explores knowledge gaps and areas for improvement to facilitate the development of more effi-cient eCO2R systems. To compete with gas-fed electrolyzers, the paper presents various approaches to enhance the performance of liquid-fed electrolyzers, leveraging their operation simplicity, scalability, low costs, high selectivity, and reasonable energy requirements. Furthermore, recent reports summarizing the performance parameters of reliable and effective electrocatalysts under ideal operating conditions, in conjunction with different electrolyzer configurations, are highlighted. This overview provides insights into the current state of the field and suggests future research directions for producing valuable chemicals with high energy efficiency (low overpotential). Ultimately, this review equips readers with fundamental knowledge and understanding necessary to improve and optimize eCO2R beyond lab-scale applications, fostering advancements in the promising field. | Sajna, M. S.; Zavahir, Sifani; Popelka, Anton; Kasak, Peter; Al-Sharshani, Ali; Onwusogh, Udeogu; Wang, Miao; Park, Hyunwoong; Han, Dong Suk | Qatar Univ, Ctr Adv Mat, Doha, Qatar; Qatar Mobil Innovat Ctr QMIC, Qatar Sci & Technol Pk QSTP, Doha, Qatar; Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea; Qatar Univ, Coll Engn, Dept Chem Engn, Doha, Qatar; Kyungpook Natl Univ, Daegu, South Korea | Han, Dong SuK/AAX-9333-2021; Kasak, peter/ABB-7974-2021 | 56019426600; 56493120500; 26432246000; 6506767573; 55340581000; 57212216330; 57212492803; 7601565583; 36139213900 | hwp@knu.ac.kr;dhan@qu.edu.qa; | JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING | J ENVIRON CHEM ENG | 2213-2929 | 2213-3437 | 11 | 5 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2023 | 7.4 | 10.3 | 3.62 | 2025-06-25 | 30 | 32 | Carbon dioxide; Electrochemical conversion; Electrolyzer; Electrocatalyst; Circular economy | HIGH-CURRENT DENSITY; GAS-DIFFUSION ELECTRODES; CARBON-DIOXIDE REDUCTION; PLUS METHANOL MEDIUM; HIGH-PRESSURE CO2; FORMIC-ACID; HIGHLY EFFICIENT; ELECTROCATALYTIC REDUCTION; COPPER ELECTRODE; SELECTIVE CONVERSION | Carbon dioxide; Circular economy; Electrocatalyst; Electrochemical conversion; Electrolyzer | Economic analysis; Electrocatalysts; Electrolysis; Electrolytic cells; Electrolytic reduction; Energy efficiency; Advanced materials; Circular economy; CO 2 reduction; Electrochemical conversion; Electrochemical reductions; Electrochemical systems; Electrochemicals; Electrolyzers; Key performance parameters; Reduce costs; Carbon dioxide | English | 2023 | 2023-10 | 10.1016/j.jece.2023.110467 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Integrated photoelectrochemical (PEC)-forward osmosis (FO) system for hydrogen production and fertigation application | This study proposes an integrated system that combines a photoelectrochemical (PEC) system and forward osmosis (FO) system in tandem operation to address water, energy, and food (WEF) scarcity. The system utilizes a combination of ammonium sulfite and ammonium sulfate solution to represent wet flue gas desulfurization products from the ammonia scrubbing process commonly used in oil and gas producing countries. Under simulated sunlight, the sulfurous solution in the PEC system is oxidized at a reduced titania nanotube array (TNA) working electrode to produce hydrogen, a clean energy source (Energy). The oxidized sulfurous solution entering the draw solution (DS) compartment of the FO unit was then diluted when the FO system operates against simulated brackish water as the feed solution (FS, Water). The DS effluent is recirculated to ensure continuous operation of both PEC and FO systems. At a certain point in time, the DS effluent is also used as a cultivation solution for basil plants, the growth is visually more favorable compared to those supplied with tap water (Food). A concentrated DS (0.8:0.2 ratio of (NH4)2SO3:(NH4)2SO4) showed excellent water desalination performance. It had a high water flux of 17 LMH with 11.8 % water recovery, highest salt rejection (98.6 % for Na+ and 98.3 for Cl-), and lowest reverse solute flux (RSF) (3.5 g & BULL;m- 2 & BULL;h-1 for SO42- , 5.25 g & BULL;m- 2 & BULL;h-1 for SO32- , 3.1 g & BULL;m- 2 & BULL;h-1 for NH4+) against 5 g & BULL;L-1 NaCl FS for 5 h, with a cathodic current density of 0.15 A & BULL;cm- 2. Overall, this study demonstrates the successful implementation of a bench-scale integrated system that produces tangible outcomes for water, energy, and food. | Zavahir, Sifani; Elmakki, Tasneem; Gulied, Mona; Shon, Ho Kyong; Park, Hyunwoong; Kakosimos, Konstantinos E.; Han, Dong Suk | Qatar Univ, Ctr Adv Mat, POB 2713, Doha, Qatar; Qatar Univ, Coll Arts & Sci, Mat Sci & Technol Master Program, POB 2713, Doha, Qatar; Univ Technol Sydney, Ctr Technol Water & Wastewater, Sch Civil & Environm Engn, Sydney, NSW 2007, Australia; Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea; Texas A&M Univ Qatar, Chem Engn Program, Doha, Qatar; Qatar Univ, Dept Chem Engn, POB 2713, Doha, Qatar | Han, Dong SuK/AAX-9333-2021; Shon, Ho/P-7057-2015; Kakosimos, Konstantinos/A-5586-2008 | 56493120500; 57221280532; 57204041429; 6701629946; 7601565583; 57201286258; 36139213900 | dhan@qu.edu.qa; | JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING | J ENVIRON CHEM ENG | 2213-2929 | 2213-3437 | 11 | 5 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2023 | 7.4 | 10.3 | 0.12 | 2025-06-25 | 1 | 1 | Forward osmosis (FO); Photoelectrochemical (PEC) system; Water-energy-food nexus; Hydrogen; Fertigation | FLUE-GAS DESULFURIZATION; NANOTUBE ARRAYS; ELECTRODES; BEHAVIOR; CAPTURE | Fertigation; Forward osmosis (FO); Hydrogen; Photoelectrochemical (PEC) system; Water-energy-food nexus | Ammonia; Desalination; Hydrogen production; Oils and fats; Osmosis membranes; Reverse osmosis; Sodium chloride; Sulfur compounds; Titanium dioxide; Draw solutions; Fertigations; Forward osmose; Forward osmosis; Integrated systems; Photoelectrochemical system; Photoelectrochemicals; Tandem operations; Water energy; Water-energy-food nexus; Effluents | English | 2023 | 2023-10 | 10.1016/j.jece.2023.110525 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Magnetic rice-straw-derived biochar for adsorptive removal of Hg(II) from aqueous solution: Optimization using response surface methodology | Magnetic rice-straw-derived biochar (MRBC) composites were synthesized by binding magnetite to the surface of the biochar for the highly efficient removal of Hg(II) from an aqueous solution. The maximum adsorption capacity of the adsorbent was 85.8 mg/g, which is much higher than those of other previously reported adsorbents for Hg(II) removal. The experimental data exhibited a good fit with a pseudo-second-order kinetic model, and the adsorption behavior followed the Langmuir isotherm. A thermodynamic study indicated that Hg(II) adsorption was spontaneous and endothermic. The individual effects and interactions of three key parameters such as initial Hg(II) concentration, adsorbent dosage, and pH were investigated by the Box-Behnken design of response surface methodology. The maximum removal efficiency of Hg(II) was 94.91% under an optimal condition of pH 3.9, an initial Hg(II) concentration of 14.3 mg/L, and an adsorbent dosage of 4.5 g/L. In the adsorption-desorption investigation, the MRBC was reusable for five adsorption-desorption cycles. The synthesized MRBC is a simple and inexpensive absorbent that can be readily isolated from a solution using a magnet after Hg(II) remediation. | Lim, Youngsu; Kim, Bolam; Jang, Jiseon; Lee, Dae Sung | Kyungpook Natl Univ, Dept Environm Engn, 80 Daehak Ro, Daegu 41566, South Korea; Korea Radioact Waste Agcy, Decommissioning Waste R&D Team, 174 Gajeong Ro, Daejeon 34129, South Korea | 57207112603; 57208922438; 56611137400; 55568524907 | pocambel@naver.com;daesung@knu.ac.kr; | JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING | J ENVIRON CHEM ENG | 2213-2929 | 2213-3437 | 11 | 3 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2023 | 7.4 | 10.3 | 1.75 | 2025-06-25 | 16 | 15 | Rice-straw-derived biochar; Mercury remediation; Adsorption; Response surface methodology; Optimization | ENHANCED HYDROGEN-PRODUCTION; KEY PROCESS VARIABLES; ACTIVATED CARBON; ADSORPTION/DESORPTION BEHAVIOR; MALACHITE GREEN; MERCURY II; MONTMORILLONITE; NANOPARTICLES; DEGRADATION; MECHANISMS | Adsorption; Mercury remediation; Optimization; Response surface methodology; Rice-straw-derived biochar | Desorption; Isotherms; Magnetite; Mercury compounds; Surface properties; Adsorbent dosage; Adsorptive removal; Biochar; Hg concentrations; Mercury remediations; Optimisations; Response-surface methodology; Rice straws; Rice-straw-derived biochar; Synthesised; Adsorption | English | 2023 | 2023-06 | 10.1016/j.jece.2023.110048 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Sulfide-occluded zeolites: Cooperative adsorption-precipitation system for near perfect decontamination of aqueous Hg species | Sulfide-occluded zeolites could allow both adsorption reaction of zeolites and precipitation reaction of sulfides to operate within one system, which leads to synergic effects on removal of toxic cationic heavy metals from aqueous systems. Here we proved that near complete decontamination of aqueous Hg cations bellow WHO guideline level of 1 ppb could be accomplished with sulfide-occluded zeolites. Interestingly, adsorption of cationic Hg species resulted in the formation of discrete HgS crusts on the surfaces of the zeolite crystals. TEM and Hg removal isotherms strongly indicated that the HgS crust played a crucial role not only in preventing the back-release of adsorbed Hg species but also in scavenging residual aqueous Hg species. Therefore, in-situ cooperation of adsorption and precipitation reactions performed by sulfide-occluded zeolites could be applied to reliable and safe Hg decontamination of aqueous systems. | Jang, Jeong-Hun; Seo, Jae-Deok; Paek, Seung-Min; Park, Man | Kyungpook Natl Univ, Sch Appl Biosci, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Chem, 80 Daehak Ro, Daegu 41566, South Korea | ; Paek, Seung-Min/E-4667-2011 | 57198251792; 57216441278; 7102686289; 36871192900 | manpark@knu.ac.kr; | JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING | J ENVIRON CHEM ENG | 2213-2929 | 2213-3437 | 11 | 5 | SCIE | ENGINEERING, CHEMICAL;ENGINEERING, ENVIRONMENTAL | 2023 | 7.4 | 10.3 | 1.75 | 2025-06-25 | 15 | 15 | Zeolites; Encapsulation; Sulfur cluster; Hg removal; HgS crust | MERCURY REMOVAL; FRAMEWORK; SULFUR; ADSORBENTS; OCCLUSION; SORBENTS; NH4NO3 | Encapsulation; Hg removal; HgS crust; Sulfur cluster; Zeolites | Adsorption; Decontamination; Heavy metals; Mercury compounds; Zeolites; Adsorption reaction; Aqueous system; Cationics; Hg removals; Hg species; HgS crust; Precipitation reaction; Precipitation systems; Sulfur clusters; Synergic effects; Sulfur compounds | English | 2023 | 2023-10 | 10.1016/j.jece.2023.110783 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Antioxidant Potential-Rich Betel Leaves (Piper betle L.) Exert Depigmenting Action by Triggering Autophagy and Downregulating MITF/Tyrosinase In Vitro and In Vivo | Each individual has a unique skin tone based on the types and quantities of melanin pigment, and oxidative stress is a key element in melanogenesis regulation. This research sought to understand the in vitro and in vivo antioxidant and depigmenting properties of betel leaves (Piper betle L.) extract (PBL) and the underlying mechanism. Ethyl acetate fractions of PBL (PBLA) demonstrated excellent phenolic content (342 +/- 4.02 mgGAE/g) and strong DPPH, ABTS radicals, and nitric oxide (NO) scavenging activity with an IC50 value of 41.52 +/- 1.02 mu g/mL, 45.60 +/- 0.56 mu g/mL, and 51.42 +/- 1.25 mu g/mL, respectively. Contrarily, ethanolic extract of PBL (PBLE) showed potent mushroom, mice, and human tyrosinase inhibition activity (IC50 = 7.72 +/- 0.98 mu g/mL, 20.59 +/- 0.83 mu g/mL and 24.78 +/- 0.56 mu g/mL, respectively). According to gas chromatography-mass spectrometry, PBL is abundant in caryophyllene, eugenol, O-eugenol, 3-Allyl-6-methoxyphenyl acetate, and chavicol. An in vitro and in vivo investigation showed that PBLE suppressed tyrosinase (Tyr), tyrosinase-related protein-1 and -2 (Trp-1 and Trp-2), and microphthalmia-associated transcription factors (MITF), decreasing the formation of melanin in contrast to the untreated control. PBLE reduced the cyclic adenosine monophosphate (cAMP) response to an element-binding protein (CREB) phosphorylation by preventing the synthesis of cAMP. Additionally, it activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases (p38), destroying Tyr and MITF and avoiding melanin production. Higher levels of microtubule-associated protein-light chain 3 (LC3-II), autophagy-related protein 5 (Atg5), Beclin 1, and lower levels of p62 demonstrate that PBLE exhibits significant anti-melanogenic effects via an autophagy-induction mechanism, both in vitro and in vivo. Additionally, PBLE significantly reduced the amount of lipid peroxidation while increasing the activity of several antioxidant enzymes in vivo, such as catalase, glutathione, superoxide dismutase, and thioredoxin. PBLE can therefore be employed in topical formulations as a potent skin-whitening agent. | Alam, Md Badrul; Park, Na Hyun; Song, Bo-Rim; Lee, Sang-Han | Kyungpook Natl Univ, Grad Sch, Dept Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Food & Bioind Res Inst, Inner Beauty Antiaging Ctr, Daegu 41566, South Korea | Lee, Seung Eun/ABG-1607-2021; Alam, Md Badrul/AFL-7668-2022 | 56706777100; 57539539700; 57223138662; 57221453703 | sang@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 12 | 2 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2023 | 6 | 10.4 | 2.08 | 2025-06-25 | 12 | 15 | antioxidant; autophagy; cAMP; melanogenesis; Piper betle | POSSIBLE INVOLVEMENT; SKIN PIGMENTATION; OXIDATIVE STRESS; MELANOGENESIS; DEGRADATION; APOPTOSIS; EXTRACT; PATHWAY; MODELS; CELLS | antioxidant; autophagy; cAMP; melanogenesis; Piper betle | English | 2023 | 2023-02 | 10.3390/antiox12020374 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Comparison of margin assessment between intraoperative digital and conventional specimen mammography in breast cancer: A preliminary study | Background: Although breast surgeons can request frozen section biopsies to evaluate margin status in breast-conserving surgery (BCS), specimen imaging is also a useful assessment tool. Intraoperative digital specimen mammography (IDSM) has recently been introduced in Korea. To estimate the clinical role of IDSM, this study compared the clinicopathologic factors of patients whose specimen was assessed with IDSM with those assessed using conventional specimen mammography (CSM).Methods: From October to December 2021, 78 breast cancer patients who underwent BCS were included in this study. The obtained specimens were assessed using IDSM (n = 44) and CSM (n = 34). Clinico-pathologic factors included margin involvement status in specimen mammography and the results of frozen section biopsies. The radiation dose emitted from the specimen after mammography was measured using a portable device.Results: There were no significant differences in clinicopathological factors between the two groups, except the type of surgery for axillary lymph nodes. The closest distance from the margin to tumor was longer in the CSM group than in the IDSM group, although the difference was not statistically significant (p = 0.894). Margin involvement was accurately detected using IDSM due to the absence of compression (p < 0.001). In addition, the sensitivity and accuracy of IDSM were higher, and the false-negative rate was lower.Conclusion: Both specimen mammography methods were highly accurate in evaluating the margin involvement status. However, the margin status could be examined more precisely using IDSM because the specimen was not compressed to perform the examination. Because the IDSM system was installed in the operating room, it not only shortened performing routes but also reduced the operating time by providing immediate results.(c) 2023 Asian Surgical Association and Taiwan Robotic Surgery Association. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/). | Keum, Heejung; Park, Ho Yong; Kang, Byeongju; Jung, Jin Hyang; Kim, Wan Wook; Lee, Jeeyeon | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Breast & Thyroid Surg, Hoguk Ro 807, Daegu 41404, South Korea | PARK, JUN-YOUNG/P-5981-2015 | 57221998716; 56564377200; 57279815300; 57209310173; 26023273400; 37079213100 | j.lee@knu.ac.kr; | ASIAN JOURNAL OF SURGERY | ASIAN J SURG | 1015-9584 | 0219-3108 | 46 | 5 | SCIE | SURGERY | 2023 | 3.5 | 10.4 | 0.33 | 2025-06-25 | 1 | 2 | Breast neoplasms; Mammography; Margins of excision; Specimen | FROZEN-SECTION ANALYSIS; CARCINOMA-IN-SITU; RADIOGRAPHY; EXCISION; RATES | Breast neoplasms; Mammography; Margins of excision; Specimen | Biopsy; Breast Neoplasms; Female; Humans; Intraoperative Care; Mammography; Mastectomy, Segmental; Retrospective Studies; biopsy; breast tumor; diagnostic imaging; female; human; mammography; partial mastectomy; pathology; peroperative care; procedures; retrospective study | English | 2023 | 2023-05 | 10.1016/j.asjsur.2022.09.094 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Development and Characterization of Inula britannica Extract-Loaded Liposomes: Potential as Anti-Inflammatory Functional Food Ingredients | We investigated the potential of Inula britannica extract encapsulated in liposomes as a functional food ingredient with enhanced bioavailability and stability. Inula britannica, known for its anti-inflammatory properties and various health benefits, was encapsulated using a liposome mass production manufacturing method, and the physical properties of liposomes were evaluated. The liposomes exhibited improved anti-inflammatory effects in lipopolysaccharide-activated RAW 264.7 macrophages, suppressing the production of pro-inflammatory mediators such as nitric oxide and prostaglandin E2 and downregulating the expression of iNOS and COX-2 transcription factors. Additionally, we observed reduced production of pro-inflammatory cytokines TNF-alpha, IL-6, and IL-1 beta, and modulation of the NF-kappa B and mitogen-activated protein kinase signaling pathways. These findings suggest that Inula britannica extract encapsulated in liposomes could serve as a valuable functional food ingredient for managing and preventing inflammation-related disorders, making it a promising candidate for incorporation into various functional food products. The enhanced absorption and stability provided by liposomal encapsulation can enable better utilization of the extract's beneficial properties, promoting overall health and well-being. | Hong, Chi Rac; Lee, Eun Ha; Jung, Young Hoon; Lee, Ju-Hoon; Paik, Hyun-Dong; Hong, Sung-Chul; Choi, Seung Jun | Seoul Natl Univ Sci & Technol, Dept Food Sci & Technol, Seoul 01811, South Korea; Korea Inst Sci & Technol, Smart Farm Res Ctr, Kangnung 25451, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Seoul Natl Univ, Res Inst Agr & Life Sci, Dept Food & Anim Biotechnol, Seoul 08826, South Korea; Konkuk Univ, Dept Food Sci & Biotechnol Anim Resources, Seoul 05029, South Korea; Kunsan Natl Univ, Dept Food Sci & Biotechnol, Gunsan 54150, South Korea; Seoul Natl Univ Sci & Technol, Ctr Funct Biomat, Seoul 01811, South Korea | Paik, Hyun-Dong/D-5226-2011; Lee, Ju-Hoon/AAK-7256-2020; Hong, Sung-Chul/ABA-5643-2021; Choi, Seung/D-2101-2010; Jung, Young Hoon/F-1703-2013 | 56391558700; 55647163955; 55550063700; 54975259000; 7005380455; 58612005000; 7408121011 | hongcr@seoultech.ac.kr;ehlee@kist.re.kr;younghoonjung@knu.ac.kr;juhlee@snu.ac.kr;hdpaik@konkuk.ac.kr;schong@ksnu.ac.kr;choisj@seoultech.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 12 | 8 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2023 | 6 | 10.4 | 1.04 | 2025-06-25 | 7 | 7 | liposomes; Inula britannica; nanocarrier; anti-inflammation; RAW 264.7 macrophage cell | NF-KAPPA-B; OXIDATIVE STRESS; NITRIC-OXIDE; INDUCED INFLAMMATION; MAPK; ACTIVATION; LIPOPOLYSACCHARIDE; ANTIOXIDANTS; MECHANISMS; FLAVONOIDS | anti-inflammation; Inula britannica; liposomes; nanocarrier; RAW 264.7 macrophage cell | English | 2023 | 2023-08 | 10.3390/antiox12081636 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Differential Effects of Histidine and Histidinamide versus Cysteine and Cysteinamide on Copper Ion-Induced Oxidative Stress and Cytotoxicity in HaCaT Keratinocytes | Metal chelators are used for various industrial and medical purposes based on their physicochemical properties and biological activities. In biological systems, copper ions bind to certain enzymes as cofactors to confer catalytic activity or bind to specific proteins for safe storage and transport. However, unbound free copper ions can catalyze the production of reactive oxygen species (ROS), causing oxidative stress and cell death. The present study aims to identify amino acids with copper chelation activities that might mitigate oxidative stress and toxicity in skin cells exposed to copper ions. A total of 20 free amino acids and 20 amidated amino acids were compared for their copper chelation activities in vitro and the cytoprotective effects in cultured HaCaT keratinocytes exposed to CuSO4. Among the free amino acids, cysteine showed the highest copper chelation activity, followed by histidine and glutamic acid. Among the amidated amino acids, cysteinamide showed the highest copper chelation activity, followed by histidinamide and aspartic acid. CuSO4 (0.4-1.0 mM) caused cell death in a concentration-dependent manner. Among the free and amidated amino acids (1.0 mM), only histidine and histidinamide prevented the HaCaT cell death induced by CuSO4 (1.0 mM). Cysteine and cysteinamide had no cytoprotective effects despite their potent copper-chelating activities. EDTA and GHK-Cu, which were used as reference compounds, had no cytoprotective effects either. Histidine and histidinamide suppressed the CuSO4-induced ROS production, glutathione oxidation, lipid peroxidation, and protein carbonylation in HaCaT cells, whereas cysteine and cysteinamide had no such effects. Bovine serum albumin (BSA) showed copper-chelating activity at 0.5-1.0 mM (34-68 mg mL(-1)). Histidine, histidinamide, and BSA at 0.5-1.0 mM enhanced the viability of cells exposed to CuCl2 or CuSO4 (0.5 mM or 1.0 mM) whereas cysteine and cysteinamide had no such effects. The results of this study suggest that histidine and histidinamide have more advantageous properties than cysteine and cysteinamide in terms of alleviating copper ion-induced toxic effects in the skin. | Ha, Jae Won; Choi, Joon Yong; Boo, Yong Chool | Kyungpook Natl Univ, Grad Sch, Dept Biomed Sci, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, BK21 Plus KNU Biomed Convergence Program, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Mol Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, 680 Gukchaebosang Ro, Daegu 41944, South Korea | 57210154932; 57576409100; 6602899130 | jaewon1226@knu.ac.kr;halo134679@knu.ac.kr;ycboo@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 12 | 4 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2023 | 6 | 10.4 | 0.74 | 2025-06-25 | 5 | 5 | copper ion; CuSO4; chelator; amino acid; histidine; histidinamide; cysteine; cysteinamide; HaCaT cells; viability; oxidative stress | CHELATING-AGENTS; ACID; TOXICITY; SALTS | amino acid; chelator; copper ion; CuSO<sub>4</sub>; cysteinamide; cysteine; HaCaT cells; histidinamide; histidine; oxidative stress; viability | English | 2023 | 2023-04 | 10.3390/antiox12040801 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Ellagic Acid Prevented Dextran-Sodium-Sulfate-Induced Colitis, Liver, and Brain Injury through Gut Microbiome Changes | Inflammatory bowel disease (IBD) affects millions of people worldwide and is considered a significant risk factor for colorectal cancer. Recent in vivo and in vitro studies reported that ellagic acid (EA) exhibits important antioxidant and anti-inflammatory properties. In this study, we investigated the preventive effects of EA against dextran sulfate sodium (DSS)-induced acute colitis, liver, and brain injury in mice through the gut-liver-brain axis. Acute colitis, liver, and brain injury were induced by treatment with 5% (w/v) DSS in the drinking water for 7 days. Freshly prepared EA (60 mg/kg/day) was orally administered, while control (CON) group mice were treated similarly by daily oral administrations with a vehicle (water). All the mice were euthanized 24 h after the final treatment with EA. The blood, liver, colon, and brain samples were collected for further histological and biochemical analyses. Co-treatment with a physiologically relevant dose (60 mg/kg/day) of EA for 7 days significantly reduced the DSS-induced gut barrier dysfunction; endotoxemia; and inflammatory gut, liver, and brain injury in mice by modulating gut microbiota composition and inhibiting the elevated oxidative and nitrative stress marker proteins. Our results further demonstrated that the preventive effect of EA on the DSS-induced IBD mouse model was mediated by blocking the NF-kappa B and mitogen-activated protein kinase (MAPK) pathway. Therefore, EA co-treatment significantly attenuated the pro-inflammatory and oxidative stress markers by suppressing the activation of NF-kappa B/MAPK pathways in gut, liver, and brain injury. These results suggest that EA, effective in attenuating IBD in a mouse model, deserves further consideration as a potential therapeutic for the treatment of inflammatory diseases. | Kim, Dong-ha; Kim, Ji-Su; Kwon, Jae-Hee; Kwun, In-Sook; Baek, Moon-Chang; Kwon, Gi-Seok; Rungratanawanich, Wiramon; Song, Byoung-Joon; Kim, Do-Kyun; Kwon, Hyo-Jung; Cho, Young-Eun | Kyungpook Natl Univ, Sch Med, Cell & Matrix Res Inst, Dept Mol Med, Daegu 41566, South Korea; Andong Natl Univ, Dept Food & Nutr, Andong 1375, South Korea; Andong Natl Univ, Dept Hort & Med Plant, Andong 1375, South Korea; NIAAA, Sect Mol Pharmacol & Toxicol, Lab Membrane Biochem & Biophys, NIH, Bethesda, MD 20892 USA; Jeonbuk Natl Univ, Korea Zoonosis Res Inst, Iksan 54596, South Korea; Chungnam Natl Univ, Coll Vet Med, Dept Vet Pathol, Daejeon 34134, South Korea | ; Kim, Dongha/HNO-9659-2023 | 57219014701; 59116401000; 58022958600; 6602312720; 7006013097; 16947529800; 57193089128; 7402560465; 57442742600; 56658978200; 56390104900 | a960112@knu.ac.kr;20235028@student.anu.ac.kr;20235243@anu.ac.kr;iskwun@anu.ac.kr;mcbaek@knu.ac.kr;gskwon@anu.ac.kr;wiramon.rungratanawanich@nih.gov;bj.song@nih.gov;dkkim714@jbnu.ac.kr;hyojung@cnu.ac.kr;yecho@anu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 12 | 10 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2023 | 6 | 10.4 | 1.48 | 2025-06-25 | 8 | 10 | inflammatory bowel disease; dextran sulfate sodium; ellagic acid; NF-kappa B/MAPK activation; anti-inflammation; antioxidant | INFLAMMATORY-BOWEL-DISEASE; KAPPA-B ACTIVATION; IN-VIVO; COLONIC INFLAMMATION; HEPATIC INFLAMMATION; DIETARY POLYPHENOLS; EXTRACT; RESVERATROL; EXPRESSION; INDUCTION | anti-inflammation; antioxidant; dextran sulfate sodium; ellagic acid; inflammatory bowel disease; NF-κB/MAPK activation | English | 2023 | 2023-10 | 10.3390/antiox12101886 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Enhanced Resistance of atnigr1 against Pseudomonas syringae pv. tomato Suggests Negative Regulation of Plant Basal Defense and Systemic Acquired Resistance by AtNIGR1 Encoding NAD(P)-Binding Rossmann-Fold in Arabidopsis thaliana | Nitric oxide (NO) regulates several biological and physiological processes in plants. This study investigated the role of Arabidopsis thaliana Negative Immune and Growth Regulator 1 (AtNIGR1), encoding an NAD(P)-binding Rossmann-fold superfamily, in the growth and immunity of Arabidopsis thaliana. AtNIGR1 was pooled from the CySNO transcriptome as a NO-responsive gene. Seeds of the knockout (atnigr1) and overexpression plants were evaluated for their response to oxidative [(hydrogen peroxide (H2O2) and methyl viologen (MV)] or nitro-oxidative [(S-nitroso-L-cysteine (CySNO) and S-nitroso glutathione (GSNO)] stress. Results showed that the root and shoot growth of atnigr1 (KO) and AtNIGR1 (OE) exhibited differential phenotypic responses under oxidative and nitro-oxidative stress and normal growth conditions. To investigate the role of the target gene in plant immunity, the biotrophic bacterial pathogen Pseudomonas syringae pv. tomato DC3000 virulent (Pst DC3000 vir) was used to assess the basal defense, while the Pst DC3000 avirulent (avrB) strain was used to investigate R-gene-mediated resistance and systemic acquired resistance (SAR). Data revealed that AtNIGR1 negatively regulated basal defense, R-gene-mediated resistance, and SAR. Furthermore, the Arabidopsis eFP browser indicated that the expression of AtNIGR1 is detected in several plant organs, with the highest expression observed in germinating seeds. All results put together suggest that AtNIGR1 could be involved in plant growth, as well as basal defense and SAR, in response to bacterial pathogens in Arabidopsis. | Al Azzawi, Tiba Nazar; Khan, Murtaza; Mun, Bong-Gyu; Lee, Sang-Uk; Imran, Muhammad; Hussain, Adil; Rolly, Nkulu Kabange; Lee, Da-Sol; Ali, Sajid; Lee, In-Jung; Yun, Byung-Wook | Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Yeungnam Univ, Dept Hort & Life Sci, Gyongsan 38541, South Korea; Natl Inst Agr Sci, Rural Dev Adm, Biosafety Div, Jeonju 55365, South Korea; Abdul Wali Khan Univ Mardan, Dept Entomol, Mardan 23200, Pakistan; Natl Inst Crop Sci, Dept Southern Area Crop Sci, RDA, Miryang 50424, South Korea | Hussain, Dr. Adil/K-6016-2018; Ali, Sajid/GLS-7322-2022; Mun, BongGyu/GYD-6010-2022; KABANGE, NKULU/AAQ-9425-2020; Imran, Muhammad/AEK-4305-2022; Lee, In-Jung/GLS-0432-2022; Hussain, Adil/K-6016-2018 | 57224980187; 57207990116; 57147241300; 57203597131; 58282433800; 41961162600; 57202031236; 57222624235; 57214290889; 16425830900; 8245123600 | bwyun@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 12 | 5 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2023 | 6 | 10.4 | 0.15 | 2025-06-25 | 0 | 2 | nitric oxide; plant growth and defense; pathogenic bacteria; NAD(P)-binding Rossmann-fold superfamily gene; Arabidopsis thaliana | NITRIC-OXIDE; TRANSCRIPTION FACTORS | Arabidopsis thaliana; NAD(P)-binding Rossmann-fold superfamily gene; nitric oxide; pathogenic bacteria; plant growth and defense | English | 2023 | 2023-04-24 | 10.3390/antiox12050989 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Epigallocatechin-3-Gallate Attenuates Myocardial Dysfunction via Inhibition of Endothelial-to-Mesenchymal Transition | Cardiac tissue damage following ischemia leads to cardiomyocyte apoptosis and myocardial fibrosis. Epigallocatechin-3-gallate (EGCG), an active polyphenol flavonoid or catechin, exerts bioactivity in tissues with various diseases and protects ischemic myocardium; however, its association with the endothelial-to-mesenchymal transition (EndMT) is unknown. Human umbilical vein endothelial cells (HUVECs) pretreated with transforming growth factor beta 2 (TGF-beta 2) and interleukin 1 beta (IL-1 beta) were treated with EGCG to verify cellular function. In addition, EGCG is involved in RhoA GTPase transmission, resulting in reduced cell mobility, oxidative stress, and inflammation-related factors. A mouse myocardial infarction (MI) model was used to confirm the association between EGCG and EndMT in vivo. In the EGCG-treated group, ischemic tissue was regenerated by regulating proteins involved in the EndMT process, and cardioprotection was induced by positively regulating apoptosis and fibrosis of cardiomyocytes. Furthermore, EGCG can reactivate myocardial function due to EndMT inhibition. In summary, our findings confirm that EGCG is an impact activator controlling the cardiac EndMT process derived from ischemic conditions and suggest that supplementation with EGCG may be beneficial in the prevention of cardiovascular disease. | Kim, Sejin; Lee, Hyunjae; Moon, Hanbyeol; Kim, Ran; Kim, Minsuk; Jeong, Seongtae; Kim, Hojin; Kim, Sang Hyeon; Hwang, Soo Seok; Lee, Min Young; Kim, Jongmin; Song, Byeong-Wook; Chang, Woochul | Pusan Natl Univ, Coll Educ, Dept Biol Educ, Pusan 46241, South Korea; Catholic Kwandong Univ, Int St Marys Hosp, Inst Biomed Convergence, Incheon 22711, South Korea; Yonsei Univ, Severance Biomed Sci Inst, Grad Sch Med Sci, Coll Med,Dept Biochem & Mol Biol, Seoul 03722, South Korea; Yonsei Univ, Inst Genet Sci, Coll Med, Chron Intractable Dis Syst Med Res Ctr, Seoul 03722, South Korea; Kyungpook Natl Univ, Coll Pharm, Dept Mol Physiol, Daegu 41566, South Korea; Sookmyung Womens Univ, Dept Life Syst, Seoul 04310, South Korea | ; Kim, Jong-Min/J-5435-2012; Song, Byeong-Wook/R-1077-2019; Hwang, Soo/AAL-3292-2020; Kim, Hyung/J-5451-2012 | 57896283200; 58294591100; 57201312637; 55859511600; 58293813800; 57258106400; 57896283300; 57870721800; 36087441100; 15119890400; 37112415400; 24345452200; 12797539700 | kimsejin1002@naver.com;jjksd@naver.com;moonstar3636@naver.com;kimran2448@naver.com;huytw01@naver.com;91seongtae@gmail.com;blue_expanse@naver.com;ksang203@yonsei.ac.kr;hwangss@yuhs.ac;vetmedic@knu.ac.kr;jkim@sookmyung.ac.kr;songbw@cku.ac.kr;wchang1975@pusan.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 12 | 5 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2023 | 6 | 10.4 | 1.93 | 2025-06-25 | 12 | 13 | EGCG; myocardial infarction; EndMT; cardioprotection; oxidative stress; inflammation; fibrosis | GREEN TEA POLYPHENOL; ACTIVATION; INFLAMMATION; MICRORNAS; FIBROSIS; CELLS | cardioprotection; EGCG; EndMT; fibrosis; inflammation; myocardial infarction; oxidative stress | English | 2023 | 2023-05-07 | 10.3390/antiox12051059 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Isolation and Identification of Limosilactobacillus reuteri PSC102 and Evaluation of Its Potential Probiotic, Antioxidant, and Antibacterial Properties | We isolated and characterized Limosilactobacillus reuteri PSC102 and evaluated its probiotic, antioxidant, and antibacterial properties. We preliminarily isolated 154 candidates from pig feces and analyzed their Gram nature, morphology, and lactic acid production ability. Based on the results, we selected eight isolates and tested their ability to produce digestive enzymes. Finally, we identified one isolate using 16S rRNA gene sequencing, namely, L. reuteri PSC102. We tested its probiotic properties in vitro, including extracellular enzyme activities, low pH and bile salt tolerance, autoaggregation and coaggregation abilities, adhesion to Caco-2 cells, antibiotic susceptibility, and hemolytic and gelatinase activities. Antioxidant activity was determined using 1-diphenyl-2-picrylhydrazyl and 2-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt radical scavenging and reducing power assays. The antibacterial activity of this strain and its culture supernatant against enterotoxigenic Escherichia coli were evaluated using a time-kill assay and disk diffusion method, respectively. L. reuteri PSC102 exhibited tolerance toward low pH and bile salt and did not produce harmful enzymes or possess hemolytic and gelatinase activities. Its intact cells and cell-free extract exhibited potential antioxidant activities, and significantly inhibited the growth of enterotoxigenic E. coli. Our results demonstrate that L. reuteri PSC102 is a potential probiotic candidate for developing functional feed. | Ali, Md. Sekendar; Lee, Eon-Bee; Lim, Suk-Kyung; Suk, Kyoungho; Park, Seung-Chun | Kyungpook Natl Univ, Brain Sci & Engn Inst, Dept Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Sch Med, Dept Pharmacol, Daegu 41944, South Korea; Kyungpook Natl Univ, Coll Vet Med, Lab Vet Pharmacokinet & Pharmacodynam, Daegu 41566, South Korea; Int Islamic Univ Chittagong, Dept Pharm, Kumira 4318, Chittagong, Bangladesh; Bacterial Dis Div, Anim & Plant Quarantine Agcy, 177 Hyeksin 8-ro, Gimcheon 39660, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, Daegu 41566, South Korea | ; Lee, Jung Bok/HHZ-3200-2022; Park, Seung-Chun/AAV-3388-2021 | 57219661221; 57216526135; 35086548900; 7005114595; 7501832396 | parksch@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 12 | 2 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2023 | 6 | 10.4 | 3.56 | 2025-06-25 | 25 | 24 | Limosilactobacillus reuteri PSC102; probiotic properties; antioxidant activity; antibacterial activity | LACTIC-ACID BACTERIA; IN-VITRO EVALUATION; LACTOBACILLUS-PLANTARUM; OXIDATIVE STRESS; SELECTION; BIFIDOBACTERIUM; TOLERANCE; VIRULENCE; IMMUNITY; GROWTH | antibacterial activity; antioxidant activity; Limosilactobacillus reuteri PSC102; probiotic properties | English | 2023 | 2023-02 | 10.3390/antiox12020238 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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