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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | High Performance Triboelectric Nanogenerator Based on Ultrastretchable Composite Electrode | Recently, stretchable triboelectric nanogenerators have attracted considerable attention as sustainable energy sources for emerging sensors and electronic applications. In this study, we fabricated a high-performance triboelectric nanogenerators (TENG) (SRC-TENG) with excellent stretchability based on a composite electrode composed of a silicone rubber and carbon nanotube (CNT). Our SRC-TENG is capable of 800% elongation and is structurally simple, robust, and easy to fabricate. Moreover, it exhibits excellent performance and delivers a maximum output of 3.52 W/m(2) at 100 M Omega, which is comparable to or even higher than those of most ultrastretchable TENGs reported. Furthermore, the output performance of the SRC-TENG is enhanced by optimizing the thickness of the composite in the range of 500-3000 mu m. This increase was due to the increase in the interfacial area between the dielectric material and CNTs and the enlargement of the contact area. The fabricated SRC-TENGs show relatively high output performance even in their stretched state (e.g. less than similar to 30% decrease at 200% elongation) and demonstrate excellent long-term stability under a continuous loading of 50,000 cycles. We believe that our design principle for developing a high-performance TENG based on a composite electrode can be further expanded to other combinations of tribomaterials for various applications. | Kim, Jinah; Park, Hyosik; Kim, Giyong; Lee, Ju-Hyuck; Park, Jinhyoung; Kim, Sung Yeol | Kyungpook Natl Univ, Dept Mech Engn, Daegu 41566, South Korea; Korea Univ Technol & Educ, Sch Mechatron Engn, Cheonan 31253, South Korea; Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept Energy Sci & Engn, Daegu 42988, South Korea | Kim, Sung Yeol/D-1412-2013; Hyuck, Lee/R-4926-2018; kim, sung/D-1412-2013 | 57224547387; 57218546343; 57354461700; 55280073900; 57225161884; 19337822900 | jhpark98@koreatech.ac.kr;sykim.knu@gmail.com; | INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING-GREEN TECHNOLOGY | INT J PR ENG MAN-GT | 2288-6206 | 2198-0810 | 10 | 6 | SCIE | ENGINEERING, MANUFACTURING;ENGINEERING, MECHANICAL;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2023 | 5.3 | 9.6 | 0.42 | 2025-06-25 | 4 | 4 | Carbon nanotubes; Nanocomposite; Stretchability; Silicon rubber; Thickness | ENERGY; TRANSPARENT | Carbon nanotubes; Nanocomposite; Silicon rubber; Stretchability; Thickness | Dielectric materials; Electrodes; Nanogenerators; Silicon; Silicone rubber; Triboelectricity; Composites electrodes; Electronics applications; Nanogenerators; Output performance; Performance; Sensor applications; Silicon rubbers; Stretchability; Sustainable energy sources; Thickness; Carbon nanotubes | English | 2023 | 2023-11 | 10.1007/s40684-023-00517-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Multi-faceted CRISPR-Cas9 strategy to reduce plant based food loss and waste for sustainable bio-economy-A review | Currently, international development requires innovative solutions to address imminent challenges like climate change, unsustainable food system, food waste, energy crisis, and environmental degradation. All the same, addressing these concerns with conventional technologies is time-consuming, causes harmful environmental impacts, and is not cost-effective. Thus, biotechnological tools become imperative for enhancing food and energy resilience through eco-friendly bio-based products by valorisation of plant and food waste to meet the goals of circular bioeconomy in conjunction with Sustainable Developmental Goals (SDGs). Genome editing can be accomplished using a revolutionary DNA modification tool, CRISPR-Cas9, through its uncomplicated guided mechanism, with great efficiency in various organisms targeting different traits. This review's main objective is to examine how the CRISPR-Cas system, which has positive features, could improve the bioeconomy by reducing food loss and waste with all-inclusive food supply chain both at on-farm and off-farm level; utilising food loss and waste by genome edited microorganisms through food valorisation; efficient microbial conversion of low-cost substrates as biofuel; valorisation of agro-industrial wastes; mitigating greenhouse gas emissions through forestry plantation crops; and protecting the ecosystem and environment. Finally, the ethical implications and regulatory issues that are related to CRISPR-Cas edited products in the international markets have also been taken into consideration. | Hemalatha, Palanivel; Abda, Ebrahim M.; Shah, Shipra; Prabhu, S. Venkatesa; Jayakumar, M.; Karmegam, N.; Kim, Woong; Govarthanan, M. | Addis Ababa Sci & Technol Univ, Coll Biol & Chem Engn, Ctr Excellence Biotechnol & Bioproc, Dept Biotechnol, POB 16417, Addis Ababa, Ethiopia; Fiji Natl Univ, Coll Agr Fisheries & Forestry, Dept Forestry, Box 1544,Kings Rd,Koronivia, Nausori, Fiji; Addis Ababa Sci & Technol Univ, Coll Biol & Chem Engn, Ctr Excellence Biotechnol & Bioproc, Dept Chem Engn, POB 16417, Addis Ababa, Ethiopia; Haramaya Univ, Haramaya Inst Technol, Dept Chem Engn, POB 138, Dire Dawa, Ethiopia; Govt Arts Coll Autonomous, PG & Res Dept Bot, Salem 636007, Tamil Nadu, India; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Saveetha Inst Med & Tech Sci, Saveetha Dent Coll & Hosp, Dept Biomat, Chennai 600077, India | ; S, Venkatesa/AAS-6778-2021; Govarthanan, Muthusamy/C-1491-2014; Natchimuthu, Karmegam/J-4745-2019; Muthusamy, Govarthanan/C-1491-2014; Karmegam, Natchimuthu/J-4745-2019 | 58771307800; 57056241700; 56266791900; 58043612900; 57196512530; 6506043230; 55581636400; 54881927600 | gova.muthu@gmail.com;drjkiothu@gmail.com; | JOURNAL OF ENVIRONMENTAL MANAGEMENT | J ENVIRON MANAGE | 0301-4797 | 1095-8630 | 332 | SCIE | ENVIRONMENTAL SCIENCES | 2023 | 8 | 9.6 | 0.73 | 2025-06-25 | 8 | 18 | Food loss; CRISPR; Genome editing; Tree genomics; Waste valorisation | ABIOTIC STRESSES; TARGETED MUTAGENESIS; GRAIN WEIGHT; CRISPR/CAS9; GENE; TOLERANCE; RICE; RESISTANCE; BACTERIAL; PATHWAY | CRISPR; Food loss; Genome editing; Tree genomics; Waste valorisation | CRISPR-Cas Systems; Crops, Agricultural; Ecosystem; Refuse Disposal; biofuel; food supply; genome; genomics; greenhouse gas; strategic approach; sustainability; waste treatment; agricultural parameters; agro-industrial waste; bioethics; biosafety; biotic stress; catering service; cereal; CRISPR-CAS9 system; crop production; ecosystem; environmental policy; environmental protection; food deprivation; food waste; forestry; genetic engineering; genetically modified food; greenhouse gas emission; human; nonhuman; phytoremediation; plant genetics; postharvest period; Review; sustainable development; tree; valorization; CRISPR Cas system; crop; waste disposal | English | 2023 | 2023-04-15 | 10.1016/j.jenvman.2023.117382 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Optimizing ethyl formate fumigation in greenhouse cucurbit crops for efficient control of major agricultural pests, Myzus persicae and Thrips palmi | Background Ethyl formate (EF) is naturally occurring volatile compound used as quarantine fumigant for pest control. Recently, conversion of uses of EF was tried from quarantine to agricultural field due to its promising efficacy. However, there is a lack of studies on the residue pattern on crops and soil and the phytotoxic mechanism of EF in greenhouse environment. This study aimed to evaluate the efficacy, residue analysis, and phytotoxicity of EF fumigation in controlling Myzus persicae and Thrips palmi, on cucurbit crops and establish an optimized fumigation strategy for use in greenhouses. Results The results showed that EF was more effective against M. persicae than against T. palmi. Residue analysis indicated that EF rapidly decomposed and was not retained after 30 min in leaves and 2 h in soil after fumigation, suggesting the potential for residue-free pest control. Phytotoxicity test revealed that watermelon was the most sensitive crop to EF, and H2O2 accumulation was observed above a concentration of 7.5 g/m(3). A strategy to reduce phytotoxicity with sodium bicarbonate during fumigation showed promising results in reducing phytotoxic effects on the crops. The optimized EF fumigation with 6 g/m(3) was applied in a greenhouse, resulting in 100% and 40% mortality of M. persicae and T. palmi, respectively, with no notable phytotoxicity and EF residue in the treated crops and soil. Conclusion This study demonstrates that optimized EF fumigation can be an environmentally sustainable method for controlling pests in greenhouses, paving the way for improved pest management practices and sustainable agriculture. Further research is needed to validate these findings and explore the potential of EF fumigation for other crops and pests. | Kim, Kyeongnam; Kim, Chaeeun; Kwon, Tae Hyung; Jeon, Hwang-Ju; Kim, Yurim; Cho, Yerin; Kim, Donghyeon; Lee, Yubin; Kim, Dongbin; Lee, Byung-Ho; Lee, Sung-Eun | Kyungpook Natl Univ, Inst Qual & Safety Evaluat Agr Prod, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Louisiana State Univ, Agr Ctr, Red River Res Stn, Bossier City, LA 71112 USA; Kyungpook Natl Univ, Dept Integrat Biol, Daegu 41566, South Korea | Jeon, Hwangju/JDW-9035-2023; Kim, Kyeongnam/KSM-2719-2024 | 57191364349; 57200245142; 57215832186; 56328792200; 57397370800; 58102413200; 57780824900; 58617076900; 57209617411; 57202841615; 55890041600 | selpest@knu.ac.kr; | CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE | CHEM BIOL TECHNOL AG | 2196-5641 | 10 | 1 | SCIE | AGRICULTURE, MULTIDISCIPLINARY | 2023 | 5.2 | 9.6 | 0.86 | 2025-06-25 | 6 | 7 | Fumigant; Ethyl formate; Residue analysis; Phytotoxicity mechanism; Sodium bicarbonate | METHYL-BROMIDE; COLD TREATMENT; PHOSPHINE; COMBINATION | Ethyl formate; Fumigant; Phytotoxicity mechanism; Residue analysis; Sodium bicarbonate | English | 2023 | 2023-10-13 | 10.1186/s40538-023-00486-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Meeting Abstract | Patterns of recurrence, treatment, and outcome of lymph node recurrence after SBRT for lung cancer | Lee, T. H.; Shin, H.; Ahn, Y. C.; Kang, M. K.; Song, C.; Kim, W. C.; Moon, S. H.; Kim, J. H.; Cho, J.; Park, H. J.; Lee, H. K.; Kim, B. H.; Kim, H. J. | Seoul Natl Univ Hosp, Dept Radiat Oncol, Seoul, South Korea; Samsung Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Kyungpook Natl Univ, Dept Radiat Oncol, Sch Med, Daegu, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Radiat Oncol, Seongnam, South Korea; Inha Univ Hosp, Dept Radiat Oncol, Incheon, South Korea; Natl Canc Ctr, Proton Therapy Ctr, Goyang, South Korea; Dongsan Med Ctr, Dept Radiat Oncol, Daegu, South Korea; Yonsei Canc Ctr, Dept Radiat Oncol, Seoul, South Korea; Hanyang Univ Hosp, Dept Radiat Oncol, Seoul, South Korea; Jeonju Jesus Hosp, Dept Radiat Oncol, Jeonju, South Korea; Seoul Natl Univ, Dept Radiat Oncol, Boramae Med Ctr, Seoul Metropolitan Govt, Seoul, South Korea | KIM, BYOUNG HYUCK/IRZ-5874-2023; Kim, Min/ACN-6827-2022; Lee, Heekwan/AAV-8373-2021; Kim, HakJae/MHP-9197-2025 | RADIOTHERAPY AND ONCOLOGY | RADIOTHER ONCOL | 0167-8140 | 1879-0887 | 182 | SCIE | ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2023 | 4.9 | 9.6 | 0 | English | 2023 | 2023-05 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Review | Producing Micro-Power with Microfluidic Enzymatic Biofuel Cells: A Comprehensive Review | Enzymatic biofuel cells (EBFCs) use enzymes as biocatalysts to produce clean energy. They have attracted much attention owing to several interesting features, such as the use of cheap and renewable biocatalysts, utilization of abundantly available high-energy-density biofuels, and their capability to operate under mild temperature and pH conditions. The integration of EBFCs into microfluidic architecture enables their application as small-scale power sources for portable, implantable, and wearable microelectronics. However, despite extensive research over the last two decades, this technology is still in the early stages of development owing to critical challenges, such as inefficient fuel oxidation, short lifetimes, and limited power density. This review paper broadly discusses various attributes of microfluidic EBFCs, focusing on the different microfabrication techniques employed to date because miniaturization is considered a promising approach for developing this technology. A short history and evolution of EBFCs are presented, after which fundamentals of the chemistry of EBFCs are briefly discussed to clarify the basic terms. In addition, various microfabrication techniques for manufacturing microfluidic EBFCs, which have been practiced over the last two decades, are reviewed thoroughly and compared according to resolution quality, fabrication convenience, and cost-effectiveness. Furthermore, potential applications of EBFCs and various obstacles to the realization of these applications are reviewed. Finally, the key challenges in producing practical and commercialized EBFCs and different approaches to overcome these challenges are discussed. This review article provides insight into the past, present, and future of this rapidly emerging microscale EBFC-based green technology. | Khan, Haroon; Tanveer, Muhammad; Park, Cheol Woo; Kim, Gyu Man | Kyungpook Natl Univ, Sch Mech Engn, 80 Daehakro, Daegu 41566, South Korea | ; Tanveer, MuhammadShahbaz/LUY-0421-2024 | 14521310700; 23486949200; 7408416474; 55664733000 | gyuman.kim@knu.ac.kr; | INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING-GREEN TECHNOLOGY | INT J PR ENG MAN-GT | 2288-6206 | 2198-0810 | 10 | 2 | SCIE | ENGINEERING, MANUFACTURING;ENGINEERING, MECHANICAL;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2023 | 5.3 | 9.6 | 0.16 | 2025-06-25 | 4 | 5 | Microfluidic; Enzymatic biofuel cell; Microfabrication; Enzyme immobilization; Electron transfer | DEPENDENT GLUCOSE-DEHYDROGENASE; FUEL-CELL; PERFORMANCE ANALYSIS; HUMAN BLOOD; PAPER; ELECTRODES; OXIDASE; ENERGY; CATHODE; LACCASE | Electron transfer; Enzymatic biofuel cell; Enzyme immobilization; Microfabrication; Microfluidic | Biofuels; Cost effectiveness; Enzymatic fuel cells; Enzyme immobilization; Microanalysis; Microelectronics; Microfluidics; Cell-be; Cell/B.E; Cell/BE; Clean energy; Electron transfer; Higher energy density; Micro Power; Micro-fabrication; Micro-fabrication techniques; Micropower; Microfabrication | English | 2023 | 2023-03 | 10.1007/s40684-022-00493-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Regional lymph node recurrence after stereotactic body radiation therapy for lung cancer: Patterns of recurrence, treatment approaches, and clinical outcomes (KROG 21-09) | Purpose: To present the multi-institutional data on patterns of recurrence, treatment approaches, and clinical outcomes for regional lymph node (LN) recurrence after stereotactic body radiation therapy (SBRT) for primary lung cancer.Materials and Methods: The medical records of 114 patients who experienced regional LN recurrence as the first recurrence after lung SBRT were retrospectively reviewed. Patterns of recurrence were classified as local recurrence, regional recurrence, and distant metastasis. Clinical outcomes including progression -free survival (PFS) and overall survival (OS) were analyzed.Results: Half of the patients had regional LN recurrence only. The most common simultaneous recurrence was distant metastasis (38.6 %). Common sites of regional recurrence were ipsilateral hilar (47.2 %), ipsi-lateral upper mediastinal (40.6 %), and subcarinal (42.5 %) LN stations. 24 (21.1 %) patients underwent salvage radiation therapy (RT), and 44 (38.6 %) patients underwent palliative treatment. Better OS was observed in the salvage RT group (p = 0.025). The 1-year PFS and OS rates were 27.7 % and 55.2 %, respec-tively, with salvage RT, 14.0 % and 39.9 %, respectively, with palliative treatment, and 22.8 % and 26.8 %, respectively, with no additional treatment. Multivariate analysis showed that salvage RT (PFS, HR 0.463, p = 0.050; OS, HR 0.312, p = 0.002), palliative treatment (PFS, HR 0.436, p = 0.013; OS, HR 0.553, p = 0.050), and simultaneous distant metastasis (PFS, HR 2.335, p = 0.005; OS, HR 1.726, p = 0.054) affected clinical outcomes.Conclusion: Many cases of regional LN recurrence are confined to the locoregional area of patients, and appropriate treatment can improve the prognosis of these patients.(c) 2023 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 183 (2023) 109572 | Lee, Tae Hoon; Shin, Hyunju; Ahn, Yong Chan; Kang, Min Kyu; Song, Changhoon; Kim, Woo Chul; Moon, Sung Ho; Kim, Jin Hee; Cho, Jaeho; Park, Hae Jin; Lee, Heui Kwan; Kim, Byoung Hyuck; Kim, Hak Jae | Seoul Natl Univ Hosp, Dept Radiat Oncol, Canc Res Inst, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Radiat Oncol, Sch Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Seoul Natl Univ, Dept Radiat Oncol, Bundang Hosp, Seongnam, South Korea; Inha Univ, Inha Univ Hosp, Dept Radiat Oncol, Sch Med, Incheon, South Korea; Natl Canc Ctr, Res Inst & Hosp, Proton Therapy Ctr, Goyang, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Radiat Oncol, Sch Med, Daegu, South Korea; Yonsei Univ, Yonsei Canc Ctr, Dept Radiat Oncol, Coll Med, Seoul, South Korea; Hanyang Univ, Dept Radiat Oncol, Coll Med, Seoul, South Korea; Presbyterian Med Ctr, Dept Radiat Oncol, Jeonju, South Korea; Seoul Natl Univ, Dept Radiat Oncol, Seoul Metropolitan Govt, Boramae Med Ctr, 20 Boramaero 5 Gil, Seoul 07061, South Korea; Seoul Natl Univ, Dept Radiat Oncol, Coll Med, Seoul, South Korea | CHO, JAEHO/JWO-2429-2024; Kim, Min/ACN-6827-2022; KANG, MIN KYU/ACI-8824-2022; Kim, HakJae/MHP-9197-2025; Lee, Tae Hoon/ABB-2997-2021; KIM, BYOUNG HYUCK/IRZ-5874-2023; Kim, Juhee/KFS-3069-2024 | 57216507584; 57222869397; 55666330600; 57201933342; 57218693367; 55730056400; 7401616549; 56441016600; 55231352500; 57201025307; 58125327400; 57205869570; 56593345800 | karlly71@snu.ac.kr;khjae@snu.ac.kr; | RADIOTHERAPY AND ONCOLOGY | RADIOTHER ONCOL | 0167-8140 | 1879-0887 | 183 | SCIE | ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2023 | 4.9 | 9.6 | 0.52 | 2025-06-25 | 3 | 3 | Lung cancer; Lymphatic metastasis; Stereotactic body radiotherapy; Salvage therapy | ABLATIVE RADIOTHERAPY; PROSPECTIVE TRIAL; DRAINAGE | Lung cancer; Lymphatic metastasis; Salvage therapy; Stereotactic body radiotherapy | Humans; Lung Neoplasms; Lymph Nodes; Neoplasm Recurrence, Local; Radiosurgery; Retrospective Studies; Treatment Outcome; durvalumab; adult; aged; aortopulmonary septal defect; Article; cancer palliative therapy; cancer prognosis; cancer recurrence; chemoradiotherapy; clinical outcome; diffusing capacity for carbon monoxide; disease exacerbation; distant metastasis; ECOG Performance Status; female; follow up; human; hypofractionated radiotherapy; lung adenocarcinoma; lung cancer; major clinical study; male; medical record review; non small cell lung cancer; overall survival; positron emission tomography-computed tomography; progression free survival; radiation dose; retrospective study; squamous cell carcinoma; stereotactic body radiation therapy; systemic therapy; lung tumor; lymph node; pathology; radiosurgery; treatment outcome; tumor recurrence | English | 2023 | 2023-06 | 10.1016/j.radonc.2023.109572 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Transcriptome and Micro-CT analysis unravels the cuticle modification in phosphine-resistant stored grain insect pest, Tribolium castaneum (Herbst) | BackgroundPhosphine (PH3) resistance in stored grain insect pests poses a significant challenge to effective pest control strategies worldwide. This study delved into understanding PH3-resistant mechanism, with the objective of informing robust and sustainable pest management strategies that could mitigate the impacts of PH3 resistance.ResultsIn this regard, the transcriptomic analysis identified 23 genes associated with chitin synthesis and cuticle formation, which showed significant expression in PH3-resistant (R) strains compared to susceptible strains. Micro-computed tomography (Micro-CT) revealed an extended and tighter cuticular structure in the PH3-R Tribolium castaneum than PH3-susceptible strains but with no changes in the cuticle thickness. This altered cuticle structure may reduce PH3 penetration through cuticles rather than completely closing spiracles during fumigation. It is also hypothesized to prevent water loss from the insect body, as water production decreased in PH3-R T. castaneum due to the down-regulation of the electron transport chain function. Validation of several chitin synthesis gene expression levels revealed consistent results with those of transcriptomic analysis.ConclusionOverall, integrating physical treatments using synthetic amorphous silicates, water absorbents, and cuticle-damaging materials during PH3 fumigation is recommended for its prolonged and controlled usage in the field. | Kim, Donghyeon; Kim, Kyeongnam; Lee, Yong Ho; Lee, Sung-Eun | Kyungpook Natl Univ, Dept Integrat Biol, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Qual & Safety Evaluat Agr Prod, Daegu 41566, South Korea; Hankyong Natl Univ, Inst Humanities & Ecol, Consensus Resilience Lab, Anseong 17579, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea | Kim, Kyeongnam/KSM-2719-2024 | 57780824900; 57191364349; 57201926028; 55890041600 | selpest@knu.ac.kr; | CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE | CHEM BIOL TECHNOL AG | 2196-5641 | 10 | 1 | SCIE | AGRICULTURE, MULTIDISCIPLINARY | 2023 | 5.2 | 9.6 | 0.86 | 2025-06-25 | 6 | 6 | Phosphine resistance mechanism; Transcriptomic analysis; Micro-CT; Stored grain insect; Chitin | STRAINS; PENETRATION; METABOLISM; MECHANISM; TOXICITY | Chitin; Micro-CT; Phosphine resistance mechanism; Stored grain insect; Transcriptomic analysis | English | 2023 | 2023-09-08 | 10.1186/s40538-023-00466-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Waterproof and Wear-Resistant Surface Treatment on Printed Parts of Polyamide 12 (PA12) by Selective Laser Sintering Using a Large Pulsed Electron Beam | Porosity is an unavoidable problem of products in powder bed fusion-based additive manufacturing. This hinders underwater applications of printed products due to water absorption by capillary force. This study reports the surface treatment of polyamide 12 (PA12) manufactured by selective laser sintering using large pulsed electron beam (LPEB) irradiations as an ecofriendly postprocessing technique. With the optimal conditions of LPEB, the surface roughness and porosity were reduced after the melting and resolidification of unmelted particles and pores without generating any dusts and using any chemicals. The surface roughness reduction increased static contact angle (CA) on the surface. From a chemical wettability investigation, the reduction of hydrophilicity after the LPEB irradiation was obtained and attributed to the elimination of hydrophilic functional groups on the surface. Due to the harmonic effects of roughness and hydrophilicity reduction, the CA on LPEB-treated surfaces was achieved around 95°. The pore-closing effect of LPEB irradiation and hydrophobic transition of PA12 protected the surface from water absorption, eliminating the capillary effect. The waterproof performance on the surface was demonstrated by releasing droplets on the surface and immersing them in ink-dispersed distilled water. The result showed potential applications of rapidly sintered PA12 in underwater. © 2022, Korean Society for Precision Engineering. | Kim, Jinsik; Chun, Doo-Man; Park, Hyung Wook; Kim, Jisoo | Graduate School of Industrial Technology, University of Ulsan, Ulsan, 44610, South Korea, UNIST Central Research Facilities, Ulsan National Institute of Science and Technology (UNIST), UNIST-gil 50, Eonyang-eup, Ulju-gun, Ulsan, 44919, South Korea; School of Mechanical Engineering, University of Ulsan, Ulsan, 44610, South Korea; School of Mechanical and Nuclear Engineering, Ulsan National Institute of Science and Technology (UNIST), UNIST-gil 50, Eonyang-eup, Ulju-gun, Ulsan, 44919, South Korea; Department of Precision Mechanical Engineering, Kyungpook National University (KNU), 2559, Gyeongsang-daero, Gyeongsangbuk-do, Sangju-si, 37224, South Korea, Department of Advanced Science and Technology Convergence, Kyungpook National University (KNU), 2559, Gyeongsang-daero, Gyeongsangbuk-do, Sangju-si, 37224, South Korea | 57225000207; 14618903800; 55537550000; 57192647685 | js.kim@knu.ac.kr; | International Journal of Precision Engineering and Manufacturing - Green Technology | INT J PR ENG MAN-GT | 2288-6206 | 2198-0810 | 10 | 1 | SCIE | ENGINEERING, MANUFACTURING;ENGINEERING, MECHANICAL;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2023 | 5.3 | 9.6 | 1.15 | 2025-06-25 | 11 | Eco-friendly manufacturing; Large pulsed electron beam; Posttreatment; Selective laser sintering; Waterproof | Contact angle; Electric conductivity; Electron beams; Hydrophilicity; Irradiation; Laser heating; Porosity; Pulsed lasers; Sintering; Surface roughness; Surface treatment; Thermal conductivity; Water treatment; Waterproofing; % reductions; Eco-friendly; Eco-friendly manufacturing; Large pulsed electron beam; Poly-amide 12; Post treatment; Pulsed electron beam irradiation; Pulsed electron beams; Waterproof; Wear-resistant; Water absorption | English | Final | 2023 | 10.1007/s40684-022-00420-4 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Review | A mechanism-based understanding of altered drug pharmacokinetics by gut microbiota | Background Pharmacomicrobiomics, which has recently emerged as a new strategy for personalized medicine, is the investigation of the influence of microbial variability on drug pharmacokinetics, efficacy, and safety. The roles of gut microbiota in drug pharmacokinetics should be thoroughly investigated, given the significant implications of gut microbiota in humans. Area covered In this paper, we provide a mechanism-based review of the impact of the gut microbiota on drug pharmacokinetics, primarily based on drug metabolism and transporters. The main mechanisms presented here are the direct metabolism of drugs by gut microbiota activity, modulation of relevant gene expression, and competitive inhibition using their metabolites. We also present the limitations of current research and provide perspectives for future investigations. Expert opinion Although prominent advances in research have paved the way to link gut microbiota and drug pharmacokinetics, there are still some limitations and restrictions to understand their intricate association. Particular attention should be paid to studies using germ-free or antibiotic-treated animals to determine associations between gut microbiota and drug pharmacokinetics. Technical limitations may also hamper advances in research on microbiota, and the expanded use of -omics techniques is expected to further improve the accuracy and efficiency of microbial investigations. More translational research that links clinical and in vitro/pre-clinical studies is warranted to facilitate microbiome-based personalized therapy. | Gulnaz, Aneela; Chang, Ji-Eun; Maeng, Han-Joo; Shin, Kwang-Hee; Lee, Kyeong-Ryoon; Chae, Yoon-Jee | Woosuk Univ, Coll Pharm, Wonju 55338, South Korea; Dongduk Womens Univ, Coll Pharm, Seoul 02748, South Korea; Gachon Univ, Coll Pharm, Incheon 21936, South Korea; Kyungpook Natl Univ, Coll Pharm, Res Inst Pharmaceut Sci, Daegu 41566, South Korea; Korea Res Inst Biosci & Biotechnol, Lab Anim Resource Ctr, Ochang 28116, South Korea; Univ Sci & Technol, Dept Biosci, Daejeon 34113, South Korea; Woosuk Univ, Res Inst Pharmaceut Sci, Wonju 55338, South Korea | 57223247232; 56143301100; 6603632250; 35216279300; 35409534300; 53463158200 | kyeongrlee@kribb.re.kr;yjchae@woosuk.ac.kr; | JOURNAL OF PHARMACEUTICAL INVESTIGATION | J PHARM INVEST | 2093-5552 | 2093-6214 | 53 | 1 | SCIE | PHARMACOLOGY & PHARMACY | 2023 | 5.3 | 9.7 | 0.72 | 2025-06-25 | 9 | 9 | Gut microbiota; Drug pharmacokinetics; Drug metabolizing enzymes; Drug transporters | INTESTINAL FLORA; IN-VITRO; METABOLIZING-ENZYMES; LITHOCHOLIC ACID; GERM-FREE; L-DOPA; CLINICAL PHARMACOKINETICS; BACTERIAL METABOLITES; HELICOBACTER-PYLORI; ELLAGIC ACID | Drug metabolizing enzymes; Drug pharmacokinetics; Drug transporters; Gut microbiota | antibiotic agent; atorvastatin; fluorouracil; glutathione; multidrug resistance associated protein 2; multidrug resistance protein 1; rosuvastatin; simvastatin; alcohol consumption; bacterial strain; Bacteroides; Bifidobacterium lactis; Caco-2 cell line; Clostridioides difficile; demethylation; dextran sulfate sodium-induced colitis; diet therapy; drug efficacy; drug interaction; drug metabolism; drug safety; drug transport; dysbiosis; Eggerthella lenta; environmental exposure; gene expression; genetic polymorphism; Ginkgo biloba; Helicobacter pylori; hydroxylation; immunocompetent cell; incubation time; intestine flora; Lactobacillus; Lactobacillus acidophilus; Lactobacillus rhamnosus; metabolite; non insulin dependent diabetes mellitus; nonhuman; personalized medicine; pharmacokinetics; protein expression; Review; systematic review; tight junction | English | 2023 | 2023-01 | 10.1007/s40005-022-00600-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | Comprehensive Analysis of Molecular Features Specific to High-grade Subtypes of Lung Adenocarcinoma Using Single-cell RNA Sequencing | Jeong, Ji Yun; Lee, Jusung; Kim, Jong Kyung; Hong, Mi Jeong; Choi, Jin Eun; Do, Young Woo; Lee, Eung Bae; Choi, Sunha; Yoo, Seung Soo; Park, Jae Yong; Lee, Shin Yup | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med, Daegu, South Korea | Lee, Ju/S-7682-2019 | LABORATORY INVESTIGATION | LAB INVEST | 0023-6837 | 1530-0307 | 103 | 3 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL;PATHOLOGY | 2023 | 5.1 | 9.7 | 0 | English | 2023 | 2023-03 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Review | Macrophage lncRNAs in cancer development: Long-awaited therapeutic targets | In the tumor microenvironment, the interplay among macrophages, cancer cells, and endothelial cells is multifaceted. Tumor-associated macrophages (TAMs), which often exhibit an M2 phenotype, contribute to tumor growth and angiogenesis, while cancer cells and endothelial cells reciprocally influence macrophage behavior. This complex interrelationship highlights the importance of targeting these interactions for the development of novel cancer therapies aimed at disrupting tumor progression and angiogenesis. Accumulating evidence underscores the indispensable involvement of lncRNAs in shaping macrophage functionality and contributing to the development of cancer. Animal studies have further validated the therapeutic potential of manipulating macrophage lncRNA activity to ameliorate disease severity and reduce morbidity rates. This review provides a survey of our current understanding of macrophage-associated lncRNAs, with a specific emphasis on their molecular targets and their regulatory impact on cancer progression. These lncRNAs predominantly govern macrophage polarization, favoring the dominance of M2 macrophages or TAMs. Exosomes or extracellular vesicles mediate lncRNA transfer between macrophages and cancer cells, affecting cellular functions of each other. Moreover, this review presents therapeutic strategies targeting cancer-associated lncRNAs. The insights and findings presented in this review pertaining to macrophage lncRNAs can offer valuable information for the development of treatments against cancer. | Arab, Imene; Park, Jeongkwang; Shin, Jae-Joon; Shin, Hyeung-Seob; Suk, Kyoungho; Lee, Won-Ha | Kyungpook Natl Univ, Sch Life Sci, BK21 Plus KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Pharmacol, Brain Sci & Engn Inst, BK21 Plus KNU Biomed Convergence Program,Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Life Sci & Biotechnol, Daegu 702701, South Korea | 58663912800; 58663723600; 58662949200; 58663723700; 7005114595; 57205609794 | whl@knu.ac.kr; | BIOCHEMICAL PHARMACOLOGY | BIOCHEM PHARMACOL | 0006-2952 | 1873-2968 | 218 | SCIE | PHARMACOLOGY & PHARMACY | 2023 | 5.3 | 9.7 | 0.65 | 2025-06-25 | 8 | 10 | Cancer; Exosome; lncRNA; Macrophage polarization; M2 macrophage; TAM; Therapeutic targets | SQUAMOUS-CELL CARCINOMA; ACUTE MYELOID-LEUKEMIA; M2 POLARIZATION; HEPATOCELLULAR-CARCINOMA; PROMOTES PROLIFERATION; TUMOR PROGRESSION; POOR-PROGNOSIS; IN-VIVO; METASTASIS; TRANSCRIPTION | Cancer; Exosome; lncRNA; M2 macrophage; Macrophage polarization; TAM; Therapeutic targets | Animals; Endothelial Cells; Macrophages; Neoplasms; RNA, Long Noncoding; Tumor Microenvironment; long untranslated RNA; long untranslated RNA; angiogenesis; cancer cell; cancer growth; carcinogenesis; cell function; endothelium cell; exosome; M2 macrophage; macrophage; morbidity; nonhuman; polarization; Review; tumor growth; tumor microenvironment; tumor-associated macrophage; animal; genetics; macrophage; neoplasm; pathology | English | 2023 | 2023-12 | 10.1016/j.bcp.2023.115890 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Numerical investigation of condensation-induced water hammer effects in horizontal and vertical cold reheat pipes | Condensation-induced water hammer (CIWH) is an unavoidable phenomenon in power generation facili-ties and must be properly adjusted for the thermal efficiency and safety of the system. This study simu-lated CIWH in a realistic steam pipe to analyze its characteristics in horizontal and vertical pipe sections. Additionally, CIWH intensities with respect to key parameter changes were explored for its mitigation. Numerical simulations for the CIWH were performed using an OpenFOAM solver, ICFMCondFOAM, which was validated for multiple phase change computational fluid dynamics (CFD) problems. The geometric and operating conditions of the cold reheat pipe of our partner company were used for CFD simulations. To assess the intensity of the water hammer effect, various inlet water flow rates and steam temperatures were employed and pressure over time was recorded at two measurement points: horizontal and vertical sections. Results of the CFD simulation show that the CIWH phenomenon behaves differently in horizon-tal and vertical pipes. CIWH strength was also evaluated using the Froude (Fr) and modified Jakob (Ja) numbers. Smaller Fr and larger Ja were found to be desirable for lowering the pressure increase ratios caused by the CIWH in both the horizontal and vertical pipe sections.(c) 2023 Elsevier Ltd. All rights reserved. | Kim, Munho; Choi, Sanghun | Kyungpook Natl Univ, Sch Mech Engn, 80 Daehak Ro, Daegu 41566, South Korea | Choi, Sanghun/AGS-7430-2022 | 57948529200; 55847101000 | s-choi@knu.ac.kr; | INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER | INT J HEAT MASS TRAN | 0017-9310 | 1879-2189 | 207 | SCIE | ENGINEERING, MECHANICAL;MECHANICS;THERMODYNAMICS | 2023 | 5 | 9.7 | 1.53 | 2025-06-25 | 12 | 11 | Reheat pipe; Phase change; Bubble collapse; Vertical shape steam pipe; Pressure increase ratio | STEAM | Bubble collapse; Phase change; Pressure increase ratio; Reheat pipe; Vertical shape steam pipe | Computational fluid dynamics; Flow of water; Steam condensers; Water hammer; Bubble collapse; Horizontal pipes; Phase Change; Pressure increase; Pressure increase ratio; Reheat pipe; Steam pipe; Vertical pipes; Vertical shape steam pipe; Water-hammer; Condensation | English | 2023 | 2023-06-15 | 10.1016/j.ijheatmasstransfer.2023.124030 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Pharmacokinetic modulation of substrate drugs via the inhibition of drug-metabolizing enzymes and transporters using pharmaceutical excipients | Background Pharmaceutical excipients are used for formulating drugs to suit their intended use and effect. These excipients influence drug solubility, manufacturability, and ability to control drug release in vitro and in vivo. They also affect intestinal permeability and metabolism by modulating drug-metabolizing enzymes and transporters.Area covered We have reviewed the effect of pharmaceutical excipients on cytochrome P450s (CYPs)-and uridine-5 '- diphospho-glucuronosyltransferases (UGTs)-mediated metabolic activities, and solute carrier transporters-and efflux transporters-mediated transport activities. We also reviewed the formulation strategies and pharmaceutical excipients that modulate drug metabolism and permeability to increase oral bioavailability (BA) by facilitating the required drug pharmacokinetics.Expert opinion The solubilization, permeation enhancement, and pharmacokinetic modulation with functional excipients are crucial for developing formulations ranging from intravenous to oral and enhancing the oral BA. Therefore, the selection of pharmaceutical excipients to formulate drugs with low solubility and permeability should be based on their safety, solubilizing capacity, interactions with intestinal metabolism, transport processes, and formulation stability. | Choi, Min-Koo; Lee, Jihoon; Song, Im-Sook | Dankook Univ, Coll Pharm, Cheonan 31116, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Coll Pharm, Vessel Organ Interact Res Ctr VOICE,BK21 FOUR Comm, Daegu 41566, South Korea | 8695781400; 57195979045; 7201564500 | isssong@knu.ac.kr; | JOURNAL OF PHARMACEUTICAL INVESTIGATION | J PHARM INVEST | 2093-5552 | 2093-6214 | 53 | 1 | SCIE | PHARMACOLOGY & PHARMACY | 2023 | 5.3 | 9.7 | 0.56 | 2025-06-25 | 7 | 7 | Pharmaceutical excipients; Drug metabolizing enzymes; Drug transporters; Pharmacokinetics; Oral bioavailability (BA) | P-GLYCOPROTEIN TRANSPORT; COMMONLY USED EXCIPIENTS; POLYETHYLENE-GLYCOL 400; CREMOPHOR-EL; IN-VITRO; INTESTINAL-ABSORPTION; GASTROINTESTINAL TRANSIT; ORAL BIOAVAILABILITY; CYCLOSPORINE PHARMACOKINETICS; CYTOCHROME-P450 ACTIVITY | Drug metabolizing enzymes; Drug transporters; Oral bioavailability (BA); Pharmaceutical excipients; Pharmacokinetics | cremophor; croscarmellose sodium; crospovidone; cytochrome P450; disodium hydrogen phosphate; drug metabolizing enzyme; excipient; glucuronosyltransferase; lactose; macrogol 400; macrogol stearate; magnesium stearate; mannitol; microcrystalline cellulose; phosphatidylcholine; poloxamer; povidone; silicon dioxide; solute carrier protein; sorbitol; starch; starch glycolate sodium; xylitol; drug bioavailability; drug formulation; drug metabolism; drug penetration; enzyme inhibition; human; IC50; in vitro study; in vivo study; metabolic activity assay; pharmacokinetics; Review; solubilization | English | 2023 | 2023-01 | 10.1007/s40005-022-00606-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | Prediction of TERT Promoter Mutational Status in Thyroid Cancer from Histologic Images using Deep Learning | Kim, Jinhee; Ko, Seokhwan; Kim, Moonsik; Park, Ji Young; Han, Hyungsoo; Cho, Junghwan; Park, Ji Young | Kyungpook Natl Univ, Chilgok Hosp, Daegu, South Korea; Tufts Univ, Medford, MA 02155 USA; Kyungpook Natl Univ, Sch Med, Daegu, South Korea | Cho, Junghwan/AAK-4752-2020 | LABORATORY INVESTIGATION | LAB INVEST | 0023-6837 | 1530-0307 | 103 | 3 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL;PATHOLOGY | 2023 | 5.1 | 9.7 | 0 | English | 2023 | 2023-03 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Article | Ultra-flexible graphene/nylon/PDMS coaxial fiber-shaped multifunctional sensor | The development of flexible and wearable devices is mainly required for tactile sensing; as such devices can adapt to complicated nonuniform surfaces, they can be applied to the human body. Nevertheless, it remains necessary to simultaneously achieve small-scale, portable, and stable developments in such devices. Thus, this work aims at fabricating a novel, lightweight, ultra-flexible, and fiber-shaped coaxial structure with a diameter of 0.51 mm using polydimethylsiloxane/graphene/nylon material, based on piezoresistive and triboelectric principles. The piezoresistive-based robotic-hand-controlled sensor thus realized exhibits a response time of 120 ms and a fast recovery time of 55 ms. Further, the piezoresistive-based sensors effectively feature whisker/joystick-guided behaviors and also sense the human finger contact. Owing to the triboelectric-based self-powered nanogenerator behavior, the resulting sensor can convert mechanical motion into electrical energy, without adversely affecting human organs. Moreover, this triboelectric-based human finger sensor can be operated under different bending modes at specific angles. Notably, this multifunctional sensor is cost-effective and suitable for various applications, including robotic-hand-controlled operations in medical surgery, whisker/joystick motions in lightweight drone technology, and navigation with high-sensitivity components. | Puneetha, Peddathimula; Mallem, Siva Pratap Reddy; Park, Sung Cheol; Kim, Seoha; Heo, Dong Hun; Kim, Cheol Min; Shim, Jaesool; An, Sung Jin; Lee, Dong-Yeon; Park, Kwi-Il | Yeungnam Univ, Coll Mech & IT Engn, Dept Robot & Intelligent Machine Engn, Gyongsan 38541, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Kumoh Natl Inst Technol, Adv Mat Res Ctr, Gumi 39177, South Korea; Yeungnam Univ, Sch Mech Engn, Gyongsan 38541, South Korea; Kumoh Natl Inst Technol, Dept Mat Sci & Engn, Gumi 39177, South Korea | An, Sung/A-2869-2009; Park, Kwiil/LKN-9445-2024; Lee, Dong-Yeon/I-7299-2019; Kim, So-Young/JFS-7698-2023; An, Sung Jin/A-2869-2009 | 56354594100; 55422639100; 57191670545; 57212495287; 57564646300; 59441985400; 16040548500; 58349582600; 55698936200; 35280874200 | sungjinan@kumoh.ac.kr;dylee@ynu.ac.kr;kipark@knu.ac.kr; | NANO RESEARCH | NANO RES | 1998-0124 | 1998-0000 | 16 | 4 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2023 | 9.6 | 9.8 | 2.39 | 2025-06-25 | 20 | 18 | extremely lightweight; ultra-flexible; piezoresistive; triboelectric sensor; human-machine; whisker | NYLON-6; NANOGENERATORS | extremely lightweight; human-machine; piezoresistive/triboelectric sensor; ultra-flexible; whisker | Cost effectiveness; Tactile sensors; Triboelectricity; Wearable sensors; Extremely lightweight; Flexible device; Human fingers; Human-machine; Multifunctional sensors; Piezo-resistive; Piezoresistive/triboelectric sensor; Ultra-flexible; Wearable devices; Whisker; Silicones | English | 2023 | 2023-04 | 10.1007/s12274-022-5235-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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