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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Meeting Abstract Dual biologic or small molecules therapy in refractory paediatric inflammatory bowel disease (DOUBLE-PIBD): A multi-center study from the paediatric IBD Porto group of ESPGHAN Cohen, S.; Olbjorn, C.; Kolho, K. L.; Aloi, M.; Musto, F.; de-Carpi, J. M.; Lozano-Ruf, A.; Yogev, D.; Matar, M.; Scarallo, L.; Bramuzzo, M.; de Ridder, L.; Kang, B.; Norden, C.; Wilson, D. C.; Tzivinikos, C.; Turner, D.; Yerushalmy-Feler, A. Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Pediat Gastroenterol Inst, Tel Aviv, Israel; Tel Aviv Univ, Pediat Gastroenterol Inst, Sackler Fac Med, Tel Aviv, Israel; Akershus Univ Hosp, Dept Paediat & Adolescent Med, Lorenskog, Norway; Childrens Hosp, Helsinki, Finland; Univ Helsinki, Helsinki, Finland; Tampere Univ, Dept Paediat Gastroenterol, Helsinki, Finland; Sapienza Univ Rome, Dept Maternal & Child Health, Pediat Gastroenterol & Liver Unit, Umberto I Hosp, Rome, Italy; Hosp St Joan Deu, Dept Pediat Gastroenterol Hepatol & Nutr, Barcelona, Spain; Hebrew Univ Jerusalem, Juliet Keiden Inst Pediat Gastroenterol & Nutr, Shaare Zedek Med Ctr, Jerusalem, Israel; Schneider Childrens Med Ctr, Tel Aviv, Israel; Tel Aviv Univ, Inst Gastroenterol Nutr & Liver Dis, Sackler Fac Med, Tel Aviv, Israel; Meyer Childrens Hosp, Gastroenterol & Nutr Unit, I-50139 Florence, Italy; IRCCS Burlo Garofolo, Gastroenterol Digest Endoscopy & Nutr Unit, Inst Maternal & Child Hlth, Trieste, Italy; Erasmus MC, Sophia Childrens Hosp, Dept Paediat Gastroenterol, Rotterdam, Netherlands; Kyungpook Natl Univ, Sch Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Copenhagen Univ Hosp, Paediat Dept, Hvidovre, Denmark; Royal Hosp Sick Children, Dept Paediat Gastroenterol & Nutr, Edinburgh, Scotland; Jalila Childrens Specialty Hosp, Pediat Gastroenterol, Dubai, U Arab Emirates 康, 奔/JMQ-0812-2023; Scarallo, Luca/AAQ-9438-2020 JOURNAL OF CROHNS & COLITIS J CROHNS COLITIS 1873-9946 1876-4479 17 SCIE GASTROENTEROLOGY & HEPATOLOGY 2023 8.3 9.4 0 English 2023 2023-02 바로가기 바로가기
Meeting Abstract Frequency and risk factors of advanced neoplasia in Korean IBD patients with Low Grade Dysplasia in previous surveillance Park, Y. E.; Kim, D. H.; Park, S. K.; Lee, Y. J.; Lee, C. K.; Kim, E. S.; Kim, K. O. Inje Univ, Div Gastroenterol, Sch Med, Haeundae Paik Hosp,Dept Internal Med, Busan, South Korea; Chonnam Natl Univ, Chonnam Natl Univ Hosp, Div Gastroenterol, Dept Internal Med,Med Sch, Gwangju, South Korea; Sungkyunkwan Univ, Div Gastroenterol, Kangbuk Samsung Hosp, Sch Med,Dept Internal Med & Gastrointes,Canc Ctr, Seoul, South Korea; Keimyung Univ, Div Gastroenterol & Hepatol, Dongsan Med Ctr, Sch Med,Dept Internal Med, Daegu, South Korea; Kyung Hee Univ, Dept Internal Med, Sch Med, Seoul, South Korea; Kyungpook Natl Univ, Div Gastroenterol, Dept Internal Med, Sch Med, Daegu, South Korea; Yeungnam Univ, Div Gastroenterol & Hepatol, Coll Med, Dept Internal Med, Daegu, South Korea Lee, Yoojin/AAB-9799-2022 JOURNAL OF CROHNS & COLITIS J CROHNS COLITIS 1873-9946 1876-4479 17 SCIE GASTROENTEROLOGY & HEPATOLOGY 2023 8.3 9.4 0 English 2023 2023-02 바로가기 바로가기
Meeting Abstract Identification of features associated with poor outcomes in pediatric patients with ulcerative proctitis: A Multicentre Study From the Paediatric IBD Porto Group of ESPGHAN Tal-Shifman, N.; Tzivinikos, C.; Gasparetto, M.; Serban, D. E.; Zifman, E.; Hojsak, I.; Ledder, O.; Feler, A. Yerushalmy; Rolandsdotter, H.; Aloi, M.; Bramuzzo, M.; Buderus, S.; Lionetti, P.; Norsa, L.; Norden, C.; Urlep, D.; Romano, C.; Shaoul, R.; Martinez-Vinson, C.; Karoliny, A.; Veereman, G.; Kang, B.; Vlckova, E.; Alvisi, P.; Kori, M.; Tavares, M.; Weiss, B.; Hussey, S.; Qamhawi, M. Essen; Palomino Perez, L. M.; Henderson, P.; Parmar, R.; Miele, E.; Rinawi, F. Firas; Lonzano-Ruf, A.; Zamvar, V.; Kolho, K. L.; Shouval, D. Schneider Childrens Med Ctr Israel, Inst Gastroenterol Nutr & Liver Dis, Petah Tiqwa, Israel; Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel; Mohammed Bin Rashid Univ, Dubai Med Coll, Al Jalila Childrens Specialty Hosp, Dept Pediat Gastroenterol, Dubai, U Arab Emirates; Barts Hlth NHS Trust, Dept Paediat Gastroenterol, Royal London Childrens Hosp, London, England; Iuliu Hatieganu Univ Med & Pharm, Emergency Clin Hosp Children, Pediat Clin 2, Cluj Napoca, Romania; Meir Med Ctr, Pediat Gastroenterol Unit, Kfar Saba, Romania; Childrens Hosp Zagreb, Referral Ctr Pediat Gastroenterol & Nutr, Zagreb, Croatia; Hebrew Univ Jerusalem, Juliet Keidan Inst Pediat Gastroenterol & Nutr, Shaare Zedek Med Ctr, Jerusalem, Israel; Tel Aviv Sourasky Med Ctr, Pediat Gastroenterol Inst, Dana Dwek Childrens Hosp, Tel Aviv, Israel; Soder Sjukhuset, Sachs Children & Youth Hosp, Dept Gastroenterol, Stockholm, Sweden; Sapienza Univ Rome, Pediat Gastroenterol Hepatol & Nutr Inst, Rome, Italy; IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy; St Marien Hosp, Dept Pediat, Bonn, Germany; Univ Florence, Meyer Childrens Hosp, Dept Neurofarba, Florence, Italy; ASST Papa Giovanni XXIII, Pediat Hepatol Gastroenterol & Transplantat Unit, Bergamo, Italy; Hvidovre Univ Hosp, Dept Pediat, Copenhagen, Denmark; Univ Med Ctr Ljubljana, Univ Childrens Hosp, Pediat Gastroenterol & Liver Unit, Ljubljana, Slovenia; G Barresi Univ Messina, Pediat Gastroenterol & Cyst Fibrosis Unit 8, Dept Human Pathol Adulthood & Childhood, Messina, Italy; Rambam Med Ctr, Pediat Gastroenterol & Nutr Inst, Ruth Childrens Hosp Haifa, Haifa, Israel; Hop Robert Debre, Assistance Publ Hop Paris, Dept Pediat Gastroenterol & Nutr, Paris, France; Heim Pal Natl Pediat Inst, Inst Gastroenterol Nutr & Liver Dis, Budapest, Hungary; Free Univ Brussels, Kidz Hlth Castle UZ Brussels, Dept Paediat Gastroenterol & Nutr, Brussels, Belgium; Kyungpook Natl Univ, Dept Pediat, Sch Med, Daegu, South Korea; Charles Univ Prague, Fac Med 2, Prague, Czech Republic; Univ Hosp Moto, Dept Pediat, Prague, Czech Republic; Maggiore Hosp, Pediat Gastroenterol Unit, Bologna, Italy; Hebrew Univ Jerusalem, Pediat Gastroenterol, Kaplan Med Ctr Rehovot, Jerusalem, Israel; Hebrew Univ Jerusalem, Fac Med, Kaplan Med Ctr Rehovot, Jerusalem, Israel; Ctr Hosp & Univ Porto, Ctr Materno Infantil Norte, Dept Pediat Gastroenterol, Porto, Portugal; Edmond & Lily Safra Childrens Hosp, Div Pediat Gastroenterol & Nutr, Tel Hashomer, Israel; Childrens Hlth Ireland UCD, Dublin, Ireland; RCSI, Dept Gastroenterol Nutr & Liver Dis, Dublin, Ireland; Karolinska Univ Hosp, Astrid Lindgren Childrens Hosp, Dept Gastroenterol Hepatol & Nutr, Stockholm, Sweden; Hosp Infantil Univ Nino Jesus, Dept Gastroenterol & Nutr, Madrid, Spain; Royal Hosp Children & Young People, Dept Paediat Gastroenterol & Nutr, Edinburgh, Midlothian, Scotland; Great North Childrens Hosp, Dept Pediat Gastroenterol, Newcastle Upon Tyne, Tyne & Wear, England; Univ Naples Federico II, Dept Translat Med Sci, Sect Pediat, Naples, Italy; Emek Med Ctr, Pediat Gastroenterol Unit, Afula, Israel; Hosp St Joan Deu, Dept Pediat Gastroenterol Hepatol & Nutr, Barcelona, Spain; Leeds Teaching Hosp NHS Trust, Leeds Childrens Hosp, Dept Paediat Gastroenterol, Leeds, W Yorkshire, England; Tampere Univ Hosp, Tampere, Finland; Univ Tampere, Tampere, Finland; Univ Helsinki, Childrens Hosp, Dept Paediat Gastroenterol, Helsinki, Finland 康, 奔/JMQ-0812-2023; Serban, Daniela Elena/V-4326-2017; Vlčková, Eva/JJE-7628-2023; Hussey, Séamus/F-8810-2015; Henderson, Paul/AAK-7867-2021; Mata Lopez, Laura/GSI-6751-2022 JOURNAL OF CROHNS & COLITIS J CROHNS COLITIS 1873-9946 1876-4479 17 SCIE GASTROENTEROLOGY & HEPATOLOGY 2023 8.3 9.4 0 English 2023 2023-02 바로가기 바로가기
Article Novel Asian-Specific Visceral Adiposity Indices Are Associated with Chronic Kidney Disease in Korean Adults Background: The Chinese visceral adiposity index (CVAI) and new visceral adiposity index (NVAI) are novel indices of visceral adiposity used to predict metabolic and cardiovascular diseases in Asian populations. However, the relationships of CVAI and NVAI with chronic kidney disease (CKD) have not been investigated. We aimed to characterize the relationships of CVAI and NVAI with the prevalence of CKD in Korean adults.Methods: A total of 14,068 participants in the 7th Korea National Health and Nutrition Examination Survey (6,182 men and 7,886 women) were included. Receiver operating characteristic (ROC) analyses were employed to compare the associations be-tween indices of adiposity and CKD, and a logistic regression model was used to characterize the relationships of CVAI and NVAI with CKD prevalence.Results: The areas under the ROC curves for CVAI and NVAI were significantly larger than for the other indices, including the visceral adiposity index and lipid accumulation product, in both men and women (all P< 0.001). In addition, high CVAI or NVAI was significantly associated with a high CKD prevalence in both men (odds ratio [OR], 2.14; 95% confidence interval [CI], 1.31 to 3.48 in CVAI and OR, 6.47; 95% CI, 2.91 to 14.38 in NVAI, P< 0.05) and women (OR, 4.87; 95% CI, 1.85 to 12.79 in CVAI and OR, 3.03; 95% CI, 1.35 to 6.82 in NVAI, P< 0.05); this association remained significant after adjustment for multiple confounding factors in men and women. Conclusion: CVAI and NVAI are positively associated with CKD prevalence in a Korean population. CVAI and NVAI may be useful for the identification of CKD in Asian populations, including in Korea. Jin, Jonghwa; Woo, Hyein; Jang, Youngeun; Lee, Won-Ki; Kim, Jung-Guk; Lee, In-Kyu; Park, Keun-Gyu; Choi, Yeon-Kyung Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Ctr Biostat, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med, 807 Hoguk Ro, Daegu 41404, South Korea Lee, In-Kyu/AAR-6374-2021 57223246243; 57214147876; 59272513400; 57207141046; 16506485900; 36071537600; 57202558343; 35335932600 kpark@knu.ac.kr;ykchoi@knu.ac.kr; DIABETES & METABOLISM JOURNAL DIABETES METAB J 2233-6079 2233-6087 47 3 SCIE ENDOCRINOLOGY & METABOLISM 2023 6.8 9.4 1.24 2025-06-25 9 7 Body fat distribution; Intra-abdominal fat; Obesity; Renal insufficiency; chronic OBESITY; POPULATION; ALBUMINURIA; LEPTIN; RISK Body fat distribution; Intra-abdominal fat; Obesity; Renal insufficiency, chronic Adiposity; Adult; Asian People; Female; Humans; Male; Nutrition Surveys; Obesity, Abdominal; Renal Insufficiency, Chronic; Republic of Korea; antidiabetic agent; antihypertensive agent; insulin; abdominal obesity; adult; aged; anemia; Article; Asian; body fat distribution; body mass; chronic kidney failure; clinical feature; confounding variable; controlled study; diabetes mellitus; dyslipidemia; estimated glomerular filtration rate; female; human; hypertension; intra-abdominal fat; intraperitoneal fat; Korea; Korean (people); lipid accumulation product index; major clinical study; male; middle aged; nutrition; prevalence; public health; questionnaire; sensitivity and specificity; visceral adiposity index; Youden index; abdominal obesity; adipose tissue inflammation; Asian; chronic kidney failure; complication; South Korea English 2023 2023-05 10.4093/dmj.2022.0099 바로가기 바로가기 바로가기 바로가기
Meeting Abstract Proactive dosing is superior to clinically based dosing in terms of endoscopic healing in paediatric patients with Crohn's disease receiving maintenance infliximab: A randomized controlled trial Kang, B.; Moon, J. S.; Lee, Y. J.; Kim, M. J.; Choe, B. H.; Ko, J. S.; Park, J. H.; Choe, Y. H. Kyungpook Natl Univ, Dept Pediat, Sch Med, Daegu, South Korea; Seoul Natl Univ, Dept Pediat, Coll Med, Seoul, South Korea; Pusan Natl Univ, Dept Pediat, Coll Med, Yangsan, South Korea; Sungkyunkwan Univ, Dept Pediat, Sch Med, Seoul, South Korea Lee, Yoojin/AAB-9799-2022; Choe, Byung-Ho/KSM-6251-2024; Ko, Jae/ABD-2701-2021; 康, 奔/JMQ-0812-2023 JOURNAL OF CROHNS & COLITIS J CROHNS COLITIS 1873-9946 1876-4479 17 SCIE GASTROENTEROLOGY & HEPATOLOGY 2023 8.3 9.4 5 English 2023 2023-02 바로가기 바로가기
Article The Efficacy and Safety of Moderate-Intensity Rosuvastatin with Ezetimibe versus High-Intensity Rosuvastatin in High Atherosclerotic Cardiovascular Disease Risk Patients with Type 2 Diabetes Mellitus: A Randomized, Multicenter, Open, Parallel, Phase 4 Study Background: To investigate the efficacy and safety of moderate-intensity rosuvastatin/ezetimibe combination compared to high -intensity rosuvastatin in high atherosclerotic cardiovascular disease (ASCVD) risk patients with type 2 diabetes mellitus (T2DM).Methods: This study was a randomized, multicenter, open, parallel phase 4 study, and enrolled T2DM subjects with an estimated 10-year ASCVD risk >= 7.5%. The primary endpoint was the low-density lipoprotein cholesterol (LDL-C) change rate after 24 -week rosuvastatin 10 mg/ezetimibe 10 mg treatment was non-inferior to that of rosuvastatin 20 mg. The achievement proportion of 10-year ASCVD risk <7.5% or comprehensive lipid target (LDL-C <70 mg/dL, non-high-density lipoprotein cholesterol <100 mg/dL, and apolipoprotein B <80 mg/dL) without discontinuation, and several metabolic parameters were explored as secondary endpoints.Results: A hundred and six participants were assigned to each group. Both groups showed significant reduction in % change of LDL-C from baseline at week 24 (-63.90 +/- 6.89 vs. -55.44 +/- 6.85, combination vs. monotherapy, P= 0.0378; respectively), but the combination treatment was superior to high-intensity monotherapy in LDL-C change (%) from baseline (least square [LS] mean difference, -8.47; 95% confidence interval, -16.44 to -0.49; P= 0.0378). The combination treatment showed a higher proportion of achieved comprehensive lipid targets rather than monotherapy (85.36% vs. 62.22% in monotherapy, P= 0.015). The ezetimibe combination significantly improved homeostasis model assessment of beta-cell function even without A1c changes (LS mean differ-ence, 17.13; P= 0.0185).Conclusion: In high ASCVD risk patients with T2DM, the combination of moderate-intensity rosuvastatin and ezetimibe was not only non-inferior but also superior to improving dyslipidemia with additional benefits compared to high-intensity rosuvas-tatin monotherapy. Moon, Jun Sung; Park, Il Rae; Kim, Sang Soo; Kim, Hye Soon; Kim, Nam Hoon; Kim, Sin Gon; Ko, Seung Hyun; Lee, Ji Hyun; Lee, Inkyu; Lee, Bo Kyeong; Won, Kyu Chang Yeungnam Univ, Coll Med, Dept Internal Med, Daegu 42415, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Dept Internal Med, Busan, South Korea; Keimyung Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Korea Univ, Coll Med, Dept Internal Med, Div Endocrinol & Metab, Seoul, South Korea; Catholic Univ Korea, St Vincents Hosp, Coll Med, Div Endocrinol & Metab,Dept Internal Med, Suwon, South Korea; Daegu Catholic Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Yuhan Corp, Clin Operat Team, Seoul, South Korea; Yeungnam Univ, Yeungnam Med Ctr, Dept Internal Med, Coll Med, 170 Hyeonchung Ro, Daegu 42415, South Korea Kim, Nam/U-1356-2019; Lee, Inkyu/F-1656-2019; Kim, Sang Soo/A-4448-2018; Kim, Hyungduk/CAH-5630-2022; Kim, Hyun/AAT-6695-2021; Kim, Sin Gon/KQU-7757-2024 55261990400; 57189328461; 56963431800; 8248249500; 56984891100; 7601582173; 7403325370; 58374693900; 59060573600; 58746300600; 57206373141 kcwon@med.yu.ac.kr; DIABETES & METABOLISM JOURNAL DIABETES METAB J 2233-6079 2233-6087 47 6 SCIE ENDOCRINOLOGY & METABOLISM 2023 6.8 9.4 1.06 2025-06-25 7 6 Cardiovascular diseases; Diabetes mellitus; type 2; Drug therapy; combination; Ezetimibe; Rosuvastatin calcium STATIN THERAPY; ATORVASTATIN Cardiovascular diseases; Diabetes mellitus, type 2; Drug therapy, combination; Ezetimibe; Rosuvastatin calcium Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Humans; Hypercholesterolemia; Rosuvastatin Calcium; apolipoprotein B; ezetimibe plus rosuvastatin; hemoglobin A1c; high density lipoprotein cholesterol; low density lipoprotein cholesterol; rosuvastatin; ezetimibe; hypocholesterolemic agent; low density lipoprotein cholesterol; rosuvastatin; adult; Article; cardiovascular risk; cell function; controlled study; coronary atherosclerosis; drug efficacy; drug safety; drug withdrawal; female; homeostasis model assessment; human; major clinical study; male; middle aged; monotherapy; multicenter study; non insulin dependent diabetes mellitus; open study; pancreas islet beta cell; phase 4 clinical trial; randomized controlled trial; unspecified side effect; atherosclerosis; cardiovascular disease; clinical trial; combination drug therapy; complication; hypercholesterolemia; non insulin dependent diabetes mellitus English 2023 2023-11 10.4093/dmj.2023.0171 바로가기 바로가기 바로가기 바로가기
Review The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4 Sarcopenia, defined as a progressive loss of muscle mass and function, is typified by mitochondrial dysfunction and loss of mito-chondrial resilience. Sarcopenia is associated not only with aging, but also with various metabolic diseases characterized by mito-chondrial dyshomeostasis. Pyruvate dehydrogenase kinases (PDKs) are mitochondrial enzymes that inhibit the pyruvate dehy-drogenase complex, which controls pyruvate entry into the tricarboxylic acid cycle and the subsequent adenosine triphosphate production required for normal cellular activities. PDK4 is upregulated in mitochondrial dysfunction-related metabolic diseases, especially pathologic muscle conditions associated with enhanced muscle proteolysis and aberrant myogenesis. Increases in PDK4 are associated with perturbation of mitochondria-associated membranes and mitochondrial quality control, which are emerging as a central mechanism in the pathogenesis of metabolic disease-associated muscle atrophy. Here, we review how mito-chondrial dysfunction affects sarcopenia, focusing on the role of PDK4 in mitochondrial homeostasis. We discuss the molecular mechanisms underlying the effects of PDK4 on mitochondrial dysfunction in sarcopenia and show that targeting mitochondria could be a therapeutic target for treating sarcopenia. Kim, Min-Ji; Sinam, Ibotombi Singh; Siddique, Zerwa; Jeon, Jae-Han; Lee, In-Kyu Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Biomed Res Inst, Daegu, South Korea; Kyungpook Natl Univ, Grad Sch, Dept Biomed Sci, Daegu, South Korea; Kyungpook Natl Univ, BK21 Plus KNU Biomed Convergence Program, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, 130 Dongdeok Ro, Daegu 41944, South Korea Kim, Min-Ji/Z-5205-2019; Lee, In-Kyu/AAR-6374-2021 57206189095; 57846985600; 58154800600; 36910340400; 59060573600 leei@knu.ac.kr; DIABETES & METABOLISM JOURNAL DIABETES METAB J 2233-6079 2233-6087 47 2 SCIE ENDOCRINOLOGY & METABOLISM 2023 6.8 9.4 2 2025-06-25 25 27 Metabolic diseases; Mitochondria; Muscular atrophy; Pyruvate dehydrogenase acetyl-transferring kinase; Pyruvate dehydrogenase complex; Sarcopenia PDK4 GENE-EXPRESSION; MUSCLE PROTEIN LOSS; SKELETAL-MUSCLE; UBIQUITIN LIGASES; INSULIN-RESISTANCE; DOWN-REGULATION; QUALITY-CONTROL; ACTIVATION; MITOPHAGY; AUTOPHAGY Metabolic diseases; Mitochondria; Muscular atrophy; Pyruvate dehydrogenase acetyl-transferring kinase; Pyruvate dehydrogenase complex; Sarcopenia Humans; Mitochondria; Protein Serine-Threonine Kinases; Pyruvates; Sarcopenia; muscle protein; proteasome; pyruvate dehydrogenase kinase 4; ubiquitin; pyruvate dehydrogenase kinase 4; pyruvic acid; disorders of mitochondrial functions; gene expression; homeostasis; human; membrane formation; mitochondrial dynamics; mitochondrial energy transfer; mitochondrion; muscle; muscle development; nonhuman; protein degradation; quality control; regulatory mechanism; Review; sarcopenia; metabolism; sarcopenia English 2023 2023-03 10.4093/dmj.2022.0305 바로가기 바로가기 바로가기 바로가기
Article Incorporating rapidly developing thunderstorm data into a deep convection scheme for improving short-term prediction of heavy rainfall over South Korea In this study, we examined the potential of the Korea Rapid-Development Thunderstorm (K-RDT) product obtained from a geostationary meteorological satellite to improve the short-term prediction of heavy rainfall caused by a mesoscale convective system over South Korea. Specifically, we utilized a simple nudging technique to integrate K-RDT data into the Simplified Arakawa Schubert (SAS) deep convection scheme of the Global/Regional Integrated Model System (GRIMs) Regional Model program (RMP). Our analysis focuses on selected cases of heavy rainfall. The nudging experiments outperformed the control experiments in terms of precipitation forecasts. Notably, the experiment that used longer nudging times produced the best results. Our results also demonstrate that the K-RDT, with its resolution of 1 km, can detect small-scale convective cells that have clear impacts on large-scale atmospheric fields. This suggests that incorporating such small-scale information into numerical weather prediction (NWP) models can significantly improve forecasting skill, especially when the model cannot represent subgrid-scale convection. Yeo, Namgu; Chang, Eun-Chul; Min, Ki-Hong Kongju Natl Univ, Dept Atmospher Sci, Gongju, South Korea; Kongju Natl Univ, Earth Environm Res Ctr, Gongju, South Korea; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 41566, South Korea ; Yeo, Namgu/KBD-2293-2024 57200341634; 55626446400; 37089364100 echang@kongju.ac.kr; WEATHER AND CLIMATE EXTREMES WEATHER CLIM EXTREME 2212-0947 42 SCIE METEOROLOGY & ATMOSPHERIC SCIENCES 2023 6.1 9.5 0 2025-06-25 0 0 LIGHTNING DATA ASSIMILATION; PRECIPITATION; PARAMETERIZATION; MODEL; PENINSULA; FORECAST; SYSTEM; IMPACT; IMPLEMENTATION; FLUX South Korea; atmospheric modeling; convective system; precipitation intensity; prediction; satellite altimetry; thunderstorm; weather forecasting English 2023 2023-12 10.1016/j.wace.2023.100624 바로가기 바로가기 바로가기 바로가기
Article Rainfall strength and area from landfalling tropical cyclones over the North Indian and western North Pacific oceans under increased CO2 conditions Climate change due to greenhouse gases has fueled more intense tropical cyclones (TCs) globally. However, the characteristics rainfall strength (RS) and rainfall area (RA) of TCs and their future changes in regional scales are not yet fully understood. Here, using ultra-high-resolution coupled model simulations, we investigate the dominant factors which control rainfall characteristics of landfalling TCs in the North Indian Ocean (NIO) and western-North Pacific (WNP) and their future change in responses to doubling and quadrupling of atmospheric CO2 concentrations. In the NIO, RS increases more than RA when CO2 rises, but the WNP shows the opposite behavior. We demonstrate that RS is highly related to the lifetime maximum intensity, landfall intensity, and latent heat flux (LHFLX), while RA depends mainly on LHFLX, relative humidity at 600 hPa, and vertical wind shear over the WNP. Our results suggest the need to establish regional-scale adaptation strategies for future changes in landfalling TCs rainfall. Moon, Mincheol; Ha, Kyung-Ja; Kim, Dasol; Ho, Chang-Hoi; Park, Doo-Sun R.; Chu, Jung-Eun; Lee, Sun-Seon; Chan, Johnny C. L. Inst Basic Sci, Ctr Climate Phys, Busan, South Korea; Pusan Natl Univ, Dept Climate Syst, Busan, South Korea; Pusan Natl Univ, BK21 Sch Earth & Environm Syst, Busan, South Korea; Univ Florida, Dept Geog, Gainesville, FL USA; Seoul Natl Univ, Sch Earth & Environm Sci, Seoul, South Korea; Kyungpook Natl Univ, Dept Earth Sci Educ, Daegu, South Korea; City Univ Hong Kong, Sch Energy & Environm, Hong Kong, Peoples R China; Pusan Natl Univ, Busan, South Korea Kim, Dasol/GWR-1499-2022; Chu, Jung-Eun/JXN-5141-2024; Park, Doo-Sun/U-9448-2019; CHAN, Johnny Chung Leung/ABI-5241-2020; Ho, Chang-Hoi/H-8354-2015; Chan, Johnny/D-8008-2013 57212007813; 8839231800; 56420697800; 7404653593; 37117659000; 55418587000; 8591161400; 55640225400 kjha@pusan.ac.kr;jungeun.chu@cityu.edu.hk; WEATHER AND CLIMATE EXTREMES WEATHER CLIM EXTREME 2212-0947 41 SCIE METEOROLOGY & ATMOSPHERIC SCIENCES 2023 6.1 9.5 0.37 2025-06-25 6 6 Tropical cyclone; Rainfall strength; Rainfall area; Climate change; CO 2 increase; CESM high -Resolution modeling TYPHOON COMMITTEE REGION; CLIMATE-CHANGE; FUTURE CHANGES; 3RD ASSESSMENT; MODEL; SIMULATION; IMPACTS; INTENSITY; FLUX CESM high-Resolution modeling; Climate change; CO<sub>2</sub> increase; Rainfall area; Rainfall strength; Tropical cyclone Indian Ocean; Indian Ocean (North); Pacific Ocean; Pacific Ocean (North); carbon dioxide; climate change; climate modeling; latent heat flux; rainfall; relative humidity; tropical cyclone; wind shear English 2023 2023-09 10.1016/j.wace.2023.100581 바로가기 바로가기 바로가기 바로가기
Meeting Abstract Albumin-Bilirubin (ALBI) score predicts hepatotoxicity after stereotactic ablative radiation therapy Joo, J. H.; Kim, W.; Nam, J.; Ki, Y.; Kim, D.; Park, D.; Jeon, H.; Kim, D. W.; Park, J. Pusan Natl Univ, Dept Radiat Oncol, Sch Med, Yangsan, South Korea; Pusan Natl Univ Hosp, Dept Radiat Oncol, Busan, South Korea; Pusan Natl Univ, Dept Radiat Oncol, Yangsan Hosp, Yangsan, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea Kim, Wiedae/JVZ-1961-2024 RADIOTHERAPY AND ONCOLOGY RADIOTHER ONCOL 0167-8140 1879-0887 182 SCIE ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2023 4.9 9.6 0 English 2023 2023-05 바로가기 바로가기
Article Assessing the impact of food trade centric on land, water, and food security in South Korea The observed and predicted changes in climate, as well as the growth in urban population, are creating severe stress on existing water resources in South Korea. By the importation of agricultural products from more waterrich countries through the virtual water concept, a country could save local water resources for other important uses. However, these imports from other countries could lead to certain vulnerabilities in the importing country derived from climate change. Therefore, through the application of the virtual water concept and the climate vulnerability index ((CVI) - measure of a country's vulnerability to indirect climate impacts), this study assessed the implication of virtual water imports and climate change through food trade, on the water, land and food security status of South Korea over the period of 2000-2017. The results showed that significant amounts of national water and land was saved through the importation of major upland crops. Virtual water imports increased significantly over time, rising from 16.2 Bm3 in 2000 to 16.5, 17.4, and 20.7 Bm3 in 2005, 2011, and 2017 respectively, with the USA, China, Australia, Brazil and Canada being the major exporters to South Korea. The study also revealed high CVI values for the oils and grains category of imported food, implying the high vulnerability of South Korea to climate change effects resulting from the import of these crops. The quantitative impacts and structural changes in virtual water trade, as well as the link between climate change, food security, international trade, and domestic water consumption could be evaluated for the sustainable management and allocation of resources. This study successfully identified and quantified the status of food trade and its environmental implications in the study area, providing insight into a better allocation of locally available resources. Odey, Golden; Adelodun, Bashir; Lee, Seulgi; Adeyemi, Khalid Adeola; Choi, Kyung Sook Kyungpook Natl Univ, Dept Agr Civil Engn, Daegu 41566, South Korea; Univ Ilorin, Dept Agr & Biosyst Engn, PMB 1515, Ilorin 240103, Nigeria; Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu, South Korea ; Adelodun, Bashir/O-2941-2018; Odey, Golden/MVV-6310-2025 57211444984; 57193774482; 57191698515; 57487234500; 54392662900 goldenodey@knu.ac.kr;adelodun.b@unilorin.edu.ng;leesg91@knu.ac.kr;khaleediadeola@gmail.com;ks.choi@knu.ac.kr; JOURNAL OF ENVIRONMENTAL MANAGEMENT J ENVIRON MANAGE 0301-4797 1095-8630 332 SCIE ENVIRONMENTAL SCIENCES 2023 8 9.6 0.87 2025-06-25 8 9 Virtual water trade; Food security; Climate vulnerability; Food trade flows; Water saving; Korea FOOTPRINT; NEXUS; CLIMATE; FLOWS; BLUE Climate vulnerability; Food security; Food trade flows; Korea; Virtual water trade; Water saving Agriculture; Commerce; Crops, Agricultural; Food Security; Food Supply; Internationality; Republic of Korea; Water; Water Supply; Australia; Brazil; Canada; China; South Korea; United States; Agricultural products; Crops; Food supply; International trade; Oils and fats; Population statistics; Sustainable development; Urban growth; Water conservation; Water resources; water; Climate vulnerability; Food security; Food trade flow; Korea; South Korea; Virtual water; Virtual water trade; Water security; Water-saving; Waters resources; climate change; food security; spatiotemporal analysis; vulnerability; water management; water resource; Article; Australia; Brazil; Canada; China; climate change; climate change vulnerability; crop; fluid intake; food; food security; land security; resource allocation; security; South Korea; sustainable development; trade (economics); United States; virtual reality; water security; water structure; agriculture; catering service; commercial phenomena; food security; international cooperation; water supply; Climate change English 2023 2023-04-15 10.1016/j.jenvman.2023.117319 바로가기 바로가기 바로가기 바로가기
Meeting Abstract Comparison of short-course with long-course palliative radiotherapy for superior vena cava syndrome Park, J.; Joo, J. H.; Lee, J. E. Kyungpook Natl Univ, Sch Med, Radiat Oncol, Daegu, South Korea; Pusan Natl Univ, Sch Med, Radiat Oncol, Yangsan Hosp, Yangsan, South Korea RADIOTHERAPY AND ONCOLOGY RADIOTHER ONCOL 0167-8140 1879-0887 182 SCIE ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2023 4.9 9.6 0 English 2023 2023-05 바로가기 바로가기
Article Definitive radiotherapy in patients with clinical T1N0M0 esophageal squamous cell carcinoma: A multicenter retrospective study (KROG 21-10) Purpose: To assess the failure pattern and analyze the treatment scheme of definitive radiation therapy (RT) for T1N0M0 esophageal squamous cell carcinoma (ESCC). Methods: We performed a multi-institutional retrospective analysis in T1N0M0 ESCC patients who underwent definitive RT from 2010 to 2019. Patterns of failure were demonstrated as in-, and out-field locoregional, and distant metastasis. In the analysis, freedom-from locoregional recurrence (FFLRR) and their association with clinicopathologic factors were evaluated. Propensity score matching in cT1b patients was done. Results: 168 patients were included with a median follow-up of 34.0 months, and 26 cT1a, 116 cT1b disease. The rates of 3-year all and locoregional recurrence for cT1a were 30.5% and 24.1% and those for cT1b were 27.1% and 25.9%, respectively. Among 116 cT1b patients, 69 patients received elective nodal irradiation (ENI) and 47 received involved field irradiation (IFI). After propensity score matching, the 3-year FFLRR rate was 84.5%. There was no difference between ENI and IFI in FFLRR (P = 0.831) and OS (P = 0.525). The 3-year FFLRR was 83.8% (95% Confidence interval (CI), 61.8-93.8%) in IFI group and 85.3% (95% CI, 65.1-94.3%) in ENI group. In multivariate analysis, concurrent chemotherapy use was marginally associated with FFLRR (Hazard ratio, 0.16; P = 0.064). Conclusion: cT1a patients who cannot receive endoscopic resection showed similar failure rates as cT1b patients, questioning the staging accuracy and raised the need for thorough treatment like chemoradiotherapy. In cT1b patients, IFI with 50 to 60 Gy and concurrent chemotherapy could be reasonable. Song, Jun Yeong; Moon, Sung Ho; Suh, Yang-Gun; Kim, Jong-Hoon; Oh, Dongryul; Noh, Jae Myoung; Jeong, Jae-Uk; Cho, Ick Joon; Kang, Min Kyu; Kim, Jin Hee; Kimi, Young Suk; Kimj, Hun Jung; Park, Woo-Yoon; Kim, Byoung Hyuck; Kim, Hak Jae Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Natl Canc Ctr, Proton Therapy Ctr, Goyang, South Korea; Asan Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Chonnam Natl Univ, Hwasun Hosp, Dept Radiat Oncol, Hwasun, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Radiat Oncol, Daegu, South Korea; Jeju Natl Univ, Sch Med, Dept Radiat Oncol, Jeju, South Korea; Inha Univ Med, Inha Univ Hosp, Dept Radiat Oncol, Inchon, South Korea; Chungbuk Natl Univ, Coll Med, Dept Radiat Oncol, Cheongju, South Korea; Seoul Natl Univ, Boramae Med Ctr, Dept Radiat Oncol, Seoul Metropolitan Govt, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Radiat Oncol, 101 Daehak Ro, Seoul, South Korea Kim, Juhee/KFS-3069-2024; Oh, Dongryul/ABB-2406-2020; Kim, HakJae/MHP-9197-2025; Kim, Jong-Hoon/F-2504-2013; KIM, BYOUNG HYUCK/IRZ-5874-2023 58035638200; 7401616549; 13408035200; 57214338837; 15839830700; 23111121800; 55449687400; 57210987659; 57201933342; 56441016600; 57203809514; 24721692800; 23020112400; 57205869570; 56593345800 ab940121@naver.com;shmoon@ncc.re.kr;karlly71@snu.ac.kr;khjae@snu.ac.kr; RADIOTHERAPY AND ONCOLOGY RADIOTHER ONCOL 0167-8140 1879-0887 189 SCIE ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2023 4.9 9.6 0.35 2025-06-25 2 2 Esophageal cancer; Radiotherapy; Failure pattern; Radiation field LYMPH-NODE METASTASIS; RADIATION-THERAPY; CHEMORADIOTHERAPY; SURGERY; CANCER; TRIAL Esophageal cancer; Failure pattern; Radiation field; Radiotherapy Carcinoma, Squamous Cell; Chemoradiotherapy; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Neoplasm Recurrence, Local; Retrospective Studies; capecitabine; cisplatin; fluorodeoxyglucose f 18; fluorouracil; adult; aged; Article; cancer chemotherapy; cancer patient; cancer radiotherapy; cancer recurrence; clinical outcome; distant metastasis; esophageal squamous cell carcinoma; female; follow up; human; lymph node irradiation; major clinical study; male; retrospective study; treatment failure; chemoradiotherapy; clinical trial; esophageal squamous cell carcinoma; esophagus tumor; multicenter study; pathology; squamous cell carcinoma; tumor recurrence English 2023 2023-12 10.1016/j.radonc.2023.109936 바로가기 바로가기 바로가기 바로가기
Meeting Abstract Definitive radiotherapy in T1N0M0 esophageal cancer: a multicenter retrospective study (KROG 21-10) Song, J. Y.; Kim, B. H.; Kang, M. K.; Chung, J. W.; Kim, J.; Moon, S. H.; Suh, Y.; Kim, J. H.; Kim, H. J.; Kim, Y. S.; Park, W. Seoul Natl Univ Hosp, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Dept Radiat Oncol, Seoul Metropolitan Govt, Boramae Med Ctr, Seoul, South Korea; Kyungpook Natl Univ, Dept Radiat Oncol, Daegu, South Korea; Chonnam Natl Univ, Dept Radiat Oncol, Hwasun Hosp, Hwasun, South Korea; Asan Med Ctr, Dept Radiat Oncol, Seoul, South Korea; Natl Canc Ctr Korea, Dept Radiat Oncol, Proton Therapy Ctr, Goyang, South Korea; Keimyung Univ, Dept Radiat Oncol, Dongsan Med Ctr, Daegu, South Korea; Inha Univ Hosp, Dept Radiat Oncol, Incheon, South Korea; Jeju Natl Univ Hosp, Dept Radiat Oncol, Jeju, South Korea; Chungbuk Natl Univ Hosp, Dept Radiat Oncol, Cheongju, South Korea KIM, BYOUNG HYUCK/IRZ-5874-2023; Kim, Suhnggwon/J-5407-2012 RADIOTHERAPY AND ONCOLOGY RADIOTHER ONCOL 0167-8140 1879-0887 182 SCIE ONCOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2023 4.9 9.6 0 English 2023 2023-05 바로가기 바로가기
Article Flashlight-Induced Explosive Chemical Reaction for Fabrication of Flameproof Nickel Electrode In this study, a unique method is proposed for the fabrication of a high-temperature-operable nickel electrode from nickel hydrazine nitrate (NHN), an explosive substance, using flashlight irradiation. NHN was synthesized by a simple mixing of nickel nitrate and hydrazine in an aqueous solution. When NHN was illuminated by a flashlight (energy density: 6 J/cm2, wavelength: 350–1000 nm, exposure time: 6 ms), it absorbed the light energy and decomposed partially, initiating an explosive chemical reaction with the gas. The temperature of NHN increased instantaneously, causing a local explosive reaction on the surface of the NHN film. The explosion reaction induced a continuous conversion of the NHN film to metallic nickel, resulting in the fabrication of a conductive nickel electrode. The fabricated nickel electrode showed an excellent conductivity (5.1 Ω, 1.2177 Ω/□ and 0.0244 Ω∙cm) and a higher thermal-oxidation resistance (13.7 Ω after the reaction at 400 °C for 30 min) than the conventional copper nanoparticle-based electrode (5 MΩ after the reaction at 250 °C for 30 min). Further, the nickel electrode, as a Joule heater, exhibited a temperature increment of 200 °C at 2.0 V. The applicability of nickel electrodes as a flameproof electrode was simply demonstrated by illuminating a LED bulb at 450 °C. Nickel-based high-temperature electronics was demonstrated by lighting an LED bulb for 60 min. This study demonstrates an advanced technique, that is, the use of the intensive pulse light (IPL) or flashlight to control explosive chemical reactions, which is a significant improvement over the conventional sintering process. © 2023, The Author(s), under exclusive licence to Korean Society for Precision Engineering. Yun, Tae Ho; Velhal, Ninad B.; Ahn, Junhyuck; Lee, Donghyun; Kim, Taeyong; Kim, Jisoo; Yim, Changyong Department of Precision Mechanical Engineering, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea; Department of Energy Chemical Engineering, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea; Department of Advanced Science and Technology Convergence, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea; Department of Energy Chemical Engineering, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea; Department of Advanced Science and Technology Convergence, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea; Department of Precision Mechanical Engineering, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea, Department of Advanced Science and Technology Convergence, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea; Department of Energy Chemical Engineering, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea, Department of Advanced Science and Technology Convergence, Kyungpook National University (KNU), 2559, Gyeongsang-Daero, Gyeongsangbuk-Do, Sangju-Si, 37224, South Korea 55383561400; 56116686900; 57925320400; 58114562700; 57934043800; 57192647685; 36877182000 js.kim@knu.ac.kr;cy.yim@knu.ac.kr; International Journal of Precision Engineering and Manufacturing - Green Technology INT J PR ENG MAN-GT 2288-6206 2198-0810 10 6 SCIE ENGINEERING, MANUFACTURING;ENGINEERING, MECHANICAL;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY 2023 5.3 9.6 0.1 2025-06-25 1 Explosive reaction; Flameproof electrode; Flashlight irradiation; High-temperature electronics; Intensive pulse light; Nickel electrode; Nickel hydrazine nitrate Electrodes; Explosives; Fabrication; Irradiation; Light emitting diodes; Nickel compounds; Nitrates; Oxidation resistance; Sintering; Surface reactions; Thermooxidation; Explosive chemicals; Explosive reaction; Flameproof electrode; Flashlight irradiation; High-temperature electronics; Intensive pulse light; Nickel electrode; Nickel hydrazine nitrates; Nitrate film; Pulse lights; Flashlights English Final 2023 10.1007/s40684-023-00503-w 바로가기 바로가기 바로가기
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