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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Meeting Abstract | Clinical Characteristics of Steroid-Dependent Ulcerative Colitis Patients after Acute Severe Ulcerative Colitis Treatment in East Asia and Australia/New Zealand: AOCC and ANZIBDC collaboration study | Kim, D. H.; Park, S. H.; Kim, H. S.; Kim, S. J.; Kim, K. O.; Lee, Y. J.; Song, E. M.; Kim, E. S.; Lee, H. S.; An, Y. K.; Begun, J.; Ruddick-Collins, L.; Fernandes, R.; Liu, J.; Cao, Q.; Kobayashi, T.; Wei, S. C. | Chonnam Natl Univ Hosp, Dept Internal Med, Div Gastroenterol, Gwnagju, South Korea; Korean Assoc Study Intestinal Dis KASID, IBD Res Grp, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Gastroenterol, Seoul, South Korea; Inflammatory Bowel Dis Ctr, Seoul, South Korea; Chonnam Natl Univ Hosp, Dept Internal Med, Div Gastroenterol, Gwangju, South Korea; Chosun Univ Hosp, Dept Internal Med, Div Gastroenterol, Gwangju, South Korea; Yeungnam Univ Hosp, Dept Internal Med, Div Gastroenterol, Daegu, South Korea; Keimyung Univ Hosp, Dept Internal Med, Div Gastroenterol, Daegu, South Korea; Ewha Womans Univ, Div Gastroenterol, Seoul Hosp, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Gastroenterol, Daegu, South Korea; Mater Hosp, Dept Gastroenterol, Brisbane, Australia; ANZIBDC Australia New Zealand IBD Consortium, Brisbane, Australia; Univ Queensland, Mater Res Inst, Brisbane, Australia; Zhejiang Chinese Med Univ, Sch Life Sci, Hangzhou, Peoples R China; Kitasato Univ, Ctr Adv IBD Res & Treatment, Kitasato Inst Hosp, Tokyo, Japan; Natl Taiwan Univ, Dept Internal Med, Natl Taiwan Univ Hosp, Taipei, Taiwan | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | Meeting Abstract | Clinical efficacy and durability of subcutaneous infliximab in patients with inflammatory bowel disease after switching from intravenous in a Korean multicenter prospective cohort study | Kim, K.; Hong, S. N.; Kang, S. B.; Lee, K. M.; Koo, J. S.; Jung, Y.; Lee, B. J.; Yoon, H.; Kim, H. W.; Lim, Y. J.; Lee, H. S.; Lee, Y. J.; Lee, J.; Lee, C. K.; Shin, S. Y.; Moon, J. M.; Seo, J.; Choi, C. H. | Chung Ang Univ Hosp, Dept Gastroenterol, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Med, Sch Med, Seoul, South Korea; Catholic Univ Korea, Daejeon St Marys Hosp, Dept Internal Med, Div Gastroenterol, Daejeon, South Korea; Catholic Univ Korea, St Vincents Hosp, Dept Internal Med, Coll Med, Suwon, South Korea; Korea Univ, Coll Med, Ansan, South Korea; Soonchunhyang Univ, Dept Internal Med, Coll Med, Cheonan, South Korea; Korea Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Internal Med, Coll Med, Yangsan, South Korea; Dongguk Univ, Ilsan Hosp, Dept Internal Med, Goyang, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Keimyung Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Chosun Univ, Sch Med, Dept Internal Med, Gwangju, South Korea; Kyung Hee Univ, Sch Med, Dept Internal Med, Seoul, South Korea; Chung Ang Univ, Gwangmyeong Hosp, Dept Internal Med, Gwangmyeong, South Korea; Chung Ang Univ Hosp, Dept Internal Med, Seoul, South Korea | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | Meeting Abstract | Clinical efficacy and durability of subcutaneous infliximab in patients with moderate-to-severe inflammatory bowel disease : a real-world data from a Korean multicentre prospective cohort study | Kim, K.; Hong, S. N. H.; Kang, S. B. K.; Lee, K. M.; Koo, J. S. K.; Jung, Y.; Lee, B. J. L.; Yoon, H. Y.; Kim, H. W.; Lim, Y. J.; Lee, H. S.; Lee, Y. J.; Lee, J.; Lee, C. K.; Moon, J. M.; Shin, S. Y.; Seo, J.; Choi, C. H. | Chung Ang Univ Hosp, Dept Gastroenterol, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Med, Seoul, South Korea; Catholic Univ, Daejeon St Marys Hosp, Div Gastroenterol, Dept Internal Med, Daejeon, South Korea; Catholic Univ Korea, Dept Internal Med, Coll Med, St Vincents Hosp, Suwon, South Korea; Korea Univ, Coll Med, Dept Internal Med, Ansan, South Korea; Soonchunhyang Univ, Coll Med, Dept Internal Med, Cheonan, South Korea; Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea; Pusan Natl Univ, Yangsan Hosp, Coll Med, Dept Internal Med, Yangsan, South Korea; Dongguk Univ, Ilsan Hosp, Dept Internal Med, Goyang, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Keimyung Univ, Sch Medicine, Dept Internal Med, Daegu, South Korea; Chosun Univ, Coll Med, Dept Internal Med, Gwangju, South Korea; Kyung Hee Univ, Sch Med, Dept Internal Med, Seoul, South Korea; Chung Ang Univ, Gwangmyeong Hosp, Dept Internal Mediciine, Gwangmyeong, South Korea; Chung Ang Univ, Gwangmyeong Hosp, Internal Med, Gwangmyeong, South Korea; Chung Ang Univ Hosp, Internal Med, Seoul, South Korea | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | Meeting Abstract | Efficacy and safety of Adalimumab in Very Early-onset IBD- A Multicentre Study from the Paediatric IBD Porto Group of ESPGHAN | Weintraub, Y.; Veit, L. Collen; Hussey, S.; Mitrova, K.; Croft, N. M.; Kang, B.; Granot, M.; D'Arcangelo, G.; Spencer, E.; Kolho, K. L.; Yeh, P. J.; Sladek, M.; Scarallo, L.; Palomino Perez, L.; Afzal, N.; de laffolie, J.; Miele, E.; Bramuzzo, M.; Olen, O.; Russell, R.; Rohani, P.; Tzivinikos, C.; Urlep, D.; van Rheenen, P.; de Ridder, L.; Yogev, D.; Schneider, A. M.; Cohen, S.; Garcia Romero, R.; Dipasquale, V.; Uhlig, H.; Shouval, D. | Schneider Childrens Med, Inst Gastroenterol Nutr & Liver Dis, Petah Tiqwa, Israel; Tel Aviv Univ, Fac Med, Tel Aviv, Israel; Boston Childrens Hosp, Boston, MA USA; Harvard Med Sch, Dept Pediat, Div Gastroenterol Hepatol & Nutr, Boston, MA USA; Childrens Hlth Ireland UCD, Dublin, Ireland; RCSI Dublin Ireland, Pediat, Dublin, Ireland; Charles Univ Prague, Fac Med 2, Prague, Czech Republic; Univ Hosp Motol, Dept Paediat, Prague, Czech Republic; Charles Univ Prague, ISCARE, Prague, Czech Republic; Charles Univ Prague, Fac Med 1, Clin & Res Ctr Inflammatory Bowel Dis, Prague, Czech Republic; Queen Mary Univ London, Fac Med, Blizard Inst, London, England; Royal London Childrens Hosp Barts Hlth NHS Trust, Paediat Gastroenterol, London, England; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Edmond & Lily Safra Childrens Hosp, Sheba Med Ctr, Pediat Gastroenterol & Nutr Unit, Tel Hashomer, Israel; Sapienza Univ Rome, Dept Womens & Childrens Hlth, Umberto I Hosp, Pediat Gastroenterol & Liver Unit, Rome, Italy; Icahn Sch Med Mt Sinai, Dept Pediat, Div Pediat Gastroenterol & Nutr, New York, NY USA; Univ Helsinki, Childrens Hosp, Helsinki, Finland; HUS, Dept Pediat Gastroenterol, Helsinki, Finland; Univ Oxford, Translat Gastroenterol Unit, Oxford, England; Jagiellonian Univ, Krakow, Poland; Polish Amer Childrens Hosp, Krakow, Poland; Meyer Children Hosp IRCCS, Gastroenterol & Nutr Unit, Florence, Italy; Univ Florence, Dept NEUROFARBA, Florence, Italy; Hosp Infantil Univ Nino Jesus, Dept Gastroenterol & Nutr, Madrid, Spain; Southampton Childrens Hosp, Dept Paediat Gastroenterol, Southampton, Hants, England; Justus Liebig Univ Giessen, Gen Pediat & Pediat Gastroenterol, Giessen, Germany; Univ Naples Federico II, Sect Pediat, Dept Translat Med Sci, Naples, Italy; IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy; Karolinska Inst, Dept Med Sona, Div Clin Epidemiol, Stockholm, Sweden; Sachs Childrens Hosp, Pediat Gastroenterol & Nutr Unit, Stockholm, Sweden; Royal Hosp Children & Young People, Dept Paediat Gastroenterol Hepatol & Nutr, Edinburgh, Midlothian, Scotland; Univ Tehran Med Sci, Pediat Ctr Excellence, Childrens Med Ctr, Pediat Gastroenterol & Hepatol Res Ctr, Tehran, Iran; Mohammed Bin Rashid Univ, Al Jalila Childrens Specialty Hosp, Dubai Med Coll, Paediat Gastroenterol Dept, Dubai, U Arab Emirates; Univ Med Ctr Ljubljana, Childrens Hosp, Dept Gastroenterol Hepatol & Nutr, Ljubljana, Slovenia; Univ Groningen, Univ Med Ctr Groningen, Dept Pediat Gastroenterol, Groningen, Netherlands; Erasmus MC, Sophia Childrens Hosp, Dept Paediat Gastroenterol, Rotterdam, Netherlands; Shaare Zedek Med Ctr, Juliet Keidan Inst Pediat Gastroenterol & Nutr, Jerusalem, Israel; Hebrew Univ Jerusalem, Fac Med, Jerusalem, Israel; Paracelsus Med Univ, Dept Pediat, Salzburg, Austria; Tel Aviv Sourasky Med Ctr, Dana Dwek Childrens Hosp, Pediat Gastroenterol Inst, Tel Aviv, Israel; Miguel Servet Hosp, Pediat Gastroenterol & Nutr Unit, Zaragoza, Spain; Univ Hosp G Martino, Pediat Gastroenterol & Cyst Fibrosis Unit, Dept Human Pathol Adulthood & Childhood G Barresi, Messina, Italy; Univ Oxford, Biomed Res Ctr, Oxford, England; Univ Oxford, Dept Paediat, Oxford, England | DIPASQUALE, VALERIA/ABE-4607-2021 | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Article | Lung Cancer Staging Using Chest CT and FDG PET/CT Free-Text Reports: Comparison Among Three ChatGPT Large Language Models and Six Human Readers of Varying Experience | BACKGROUND. Although radiology reports are commonly used for lung cancer staging, this task can be challenging given radiologists' variable reporting styles as well as reports' potentially ambiguous and/or incomplete staging-related information. OBJECTIVE. The purpose of this study was to compare the performance of ChatGPT large language models (LLMs) and human readers of varying experience in lung cancer staging using chest CT and FDG PET/CTfree-text reports. METHODS. This retrospective study included 700 patients (mean age, 73.8 +/- 29.5 [SD] years; 509 men, 191 women) from four institutions in Korea who underwent chest CT or FDG PET/CT for non-small cell lung cancer initial staging from January 2020 to December 2023. Examinations' reports used a free-text format, written exclusively in English or in mixed English and Korean. Two thoracic radiologists in consensus determined the overall stage group (IA, IB, IIA, IIB, IIIA, IIIB, IIIC, IVA, or IVB) for each report using the 8th-edition AJCC Cancer Staging Manual to establish the reference standard. Three ChatGPT models (GPT-4o, GPT-4, GPT-3.5) determined an overall stage group for each report using a script-based application programming interface, zero-shot learning, and a prompt incorporating a staging system summary. The code for this web application was made publicly available through a GitHub repository ( https://github.com/elmidion/GPTIₙfₒᵣₘₐₜᵢₒₙEₓₜᵣₐcₜₒᵣ ). Six human readers (two fellowship-trained radiologists with less experience than the radiologists who determined the reference standard, two fellows, and two residents) also independently determined overall stage groups. GPT-4o's overall accuracy for determining the correct stage among the nine groups was compared with that of the other LLMs and human readers using McNemar tests. RESULTS. GPT-4o had an overall staging accuracy of 74.1%, significantly better than the accuracy of GPT-4 (70.1%, p = .02), GPT-3.5 (57.4%, p < .001), and resident 2 (65.7%, p < .001); significantly worse than the accuracy of fellowship-trained radiologist 1 (82.3%, p < .001) and fellowship-trained radiologist 2 (85.4%, p < .001); and not significantly different from the accuracy of fellow 1 (77.7%, p = .09), fellow 2 (75.6%, p = .53), and resident 1 (72.3%, p = .42). CONCLUSION. The best-performing model, GPT-4o, showed no significant difference in staging accuracy versus fellows but showed significantly worse performance versus fellowship-trained radiologists. The findings do not support use of LLMs for lung cancer staging in place of expert health care professionals. CLINICAL IMPACT. The findings indicate the importance of domain expertise for performing complex specialized tasks such as cancer staging. | Lee, Jong Eun; Park, Ki-Seong; Kim, Yun-Hyeon; Song, Ho-Chun; Park, Byunggeon; Jeong, Yeon Joo | Asan Med Ctr, Dept Radiol, Seoul, South Korea; Asan Med Ctr, Res Inst Radiol, Seoul, South Korea; Chonnam Natl Univ Hosp, Dept Nucl Med, Gwangju, South Korea; Chonnam Natl Univ Hosp, Dept Radiol, Gwangju, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Radiol, Daegu, South Korea; Pusan Natl Univ, Yangsan Hosp, Res Inst Convergence Biomed Sci & Technol, Sch Med,Dept Radiol, 20 Geumo Ro Mulgeum Eup, Yangsan 50612, South Korea | Lee, Jung-Seok/L-6826-2019 | 57196009389; 56461707800; 35313444300; 7404037329; 57211532915; 57706214000 | jeongyj0610@gmail.com; | AMERICAN JOURNAL OF ROENTGENOLOGY | AM J ROENTGENOL | 0361-803X | 1546-3141 | 223 | 6 | SCIE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2024 | 6.1 | 7.8 | 4.08 | 2025-05-07 | 12 | 12 | free-text report; generative pretrained transformer; large language model; lung cancer; natural language processing | free-text report; generative pretrained transformer; large language model; lung cancer; natural language processing | accuracy; aged; Article; cancer staging; ChatGPT; computer assisted tomography; female; health care personnel; histology; human; lung cancer; lung metastasis; lung nodule; lymph node; lymph node dissection; lymph node metastasis; major clinical study; male; metastasis; non small cell lung cancer; positron emission tomography-computed tomography; radiologist; resident; retrospective study | English | 2024 | 2024-12 | 10.2214/ajr.24.31696 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Modulation of warm temperature-sensitive growth using a phytochrome B dark reversion variant, phyB[G515E], in Arabidopsis and rice | Introduction: Ambient temperature-induced hypocotyl elongation in Arabidopsis seedlings is sensed by the epidermis-localized phytochrome B (phyB) and transduced into auxin biosynthesis via a basic helix-loop-helix transcription factor, phytochrome-interacting factor 4 (PIF4). Once synthesized, auxin travels down from the cotyledons to the hypocotyl, triggering hypocotyl cell elongation. Thus, the phyB-PIF4 module involved in thermosensing and signal transduction is a potential genetic target for engineering warm temperature-insensitive plants. Objectives: This study aims to manipulate warm temperature-induced elongation of plants at the post- translational level using phyB variants with dark reversion, the expression of which is subjected to heat stress. Methods: The thermosensitive growth response of Arabidopsis was manipulated by expressing the single amino acid substitution variant of phyB (phyB[G515E]), which exhibited a lower dark reversion rate than wild-type phyB. Other variants with slow (phyB[G564E]) or rapid (phyB[S584F]) dark reversion or light insensitivity (phyB[G767R]) were also included in this study for comparison. Warming-induced transient expression of phyB variants was achieved using heat shock-inducible promoters. Arabidopsis PHYB [G515E] and PHYB[G564E] were also constitutively expressed in rice in an attempt to manipulate the heat sensitivity of a monocotyledonous plant species. Results: At an elevated temperature, Arabidopsis seedlings transiently expressing PHYB[G515E] under the control of a heat shock-inducible promoter exhibited shorter hypocotyls than those expressing PHYB and other PHYB variant genes. This warm temperature-insensitive growth was related to the lowered PIF4 and auxin responses. In addition, transgenic rice seedlings expressing Arabidopsis PHYB[G515E] and PHYB[G564E] showed warm temperature-insensitive shoot growth. Conclusion: Transient expression of phyB variants with altered dark reversion rates could serve as an effective optogenetic technique for manipulating PIF4-auxin-mediated thermomorphogenic responses in plants. (c) 2024 The Authors. Published by Elsevier B.V. on behalf of Cairo University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | Jeon, Jin; Rahman, Md Mizanor; Yang, Hee Wook; Kim, Jaewook; Gam, Ho-Jun; Song, Ji Young; Jeong, Seok Won; Kim, Jeong-Il; Choi, Myoung-Goo; Shin, Dong-Ho; Choi, Giltsu; Shim, Donghwan; Jung, Jae-Hoon; Lee, In-Jung; Jeon, Jong-Seong; Park, Youn-Il | Chungnam Natl Univ, Dept Biol Sci, Daejeon 34134, South Korea; Kyung Hee Univ, Grad Sch Green Bio Sci, Yongin 17104, South Korea; Kyung Hee Univ, Crop Biotech Inst, Yongin 17104, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Chonnam Natl Univ, Dept Mol Biotechnol, Gwangju 61186, South Korea; Chonnam Natl Univ, Kumho Life Sci Lab, South Korea 61186, South Korea; Rural Dev Adm, Natl Inst Crop Sci, Wonju 55365, South Korea; Korea Adv Inst Sci & Technol, Dept Biol Sci, Daejeon 34141, South Korea; Sungkyunkwan Univ, Dept Biol Sci, Suwon 16419, South Korea | Lee, In-Jung/GLS-0432-2022; Choi, Giltsu/AFD-3805-2022; Kim, Joonghee/C-9811-2014; Park, Youn-Il/S-2997-2019; , Rahman Md Mizanor(유전생명공학과)/LPQ-1634-2024; Jeon, Jong-Seong/AAJ-2161-2020; Gam, Hojun/MXJ-6421-2025 | 57189260194; 57211095206; 57214116357; 57190177084; 57450591400; 56969965000; 55463311800; 7601379315; 57222092621; 57220889252; 55654809000; 7004320228; 57213220517; 16425830900; 7202411379; 7405372282 | jjeon@khu.ac.kr;yipark@cnu.ac.kr; | JOURNAL OF ADVANCED RESEARCH | J ADV RES | 2090-1232 | 2090-1224 | 63 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 13 | 7.8 | 0.41 | 2025-05-07 | 2 | 2 | Arabidopsis; Heat shock-inducible promoters; Phytochrome B dark reversion variants; PIF4; Rice; Thermomorphogenic response | RED/FAR-RED LIGHT; GENE-EXPRESSION; TERMINAL-DOMAIN; CELL-DIVISION; PROTEIN; RESPONSES; LEAF; TIME; PHOTORECEPTORS; TRANSFORMATION | Arabidopsis; Heat shock-inducible promoters; Phytochrome B dark reversion variants; PIF4; Rice; Thermomorphogenic response | Arabidopsis; Arabidopsis Proteins; Basic Helix-Loop-Helix Transcription Factors; Gene Expression Regulation, Plant; Hot Temperature; Hypocotyl; Indoleacetic Acids; Oryza; Phytochrome B; Plants, Genetically Modified; Seedlings; Signal Transduction; Temperature; Arabidopsis protein; basic helix loop helix transcription factor; indoleacetic acid derivative; PHYB protein, Arabidopsis; phytochrome B; PIF4 protein, Arabidopsis; Arabidopsis; gene expression regulation; genetics; growth, development and aging; high temperature; hypocotyl; metabolism; Oryza; seedling; signal transduction; temperature; transgenic plant | English | 2024 | 2024-09 | 10.1016/j.jare.2023.11.001 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | mQUIC: Use of QUIC for Handover Support with Connection Migration in Wireless/Mobile Networks | The QUIC (formerly known as quick UDP Internet connection) protocol offers many distinct advantages over TCP, such as low-latency connection establishment, multi-streaming, and connection migration, which can be used to maintain a connection even when the associated IP address is changed due to handover. This article presents an effective approach for using connection migration of QUIC to support seamless handover for mobile clients in wireless networks, referred to as mobile QUIC (mQUIC) handover. The handover event is detected by using an error event for data transmission or a handover detection timer. Upon detection, the mobile client obtains a new IP address from its underlying routing table and performs the path validation and connection migration operations with the remote server over the newly obtained IP address. mQUIC handover can be used to provide robust and seamless handover for mobile clients in the heterogenous wireless/mobile networks. Real testbed experiments with WiFi and commercial 5G cellular networks of SK Telecom in Korea demonstrate that the proposed mQUIC handover can provide significant performance gains over the normal QUIC handover with a new connection establishment. | Kim, So-Yong; Koh, Seok-Joo | Kyungpook Natl Univ, Daegu, South Korea | Kim, So-Yong/JJG-1016-2023 | 57218590446; 8958394800 | smalldragon024@gmail.com;sjkoh@knu.ac.kr; | IEEE COMMUNICATIONS MAGAZINE | IEEE COMMUN MAG | 0163-6804 | 1558-1896 | 62 | 4 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2024 | 8.2 | 7.8 | 0 | 2025-05-07 | 0 | 0 | Handover; IP networks; Servers; Routing; Delays; Table lookup; 5G mobile communication; Wireless networks; Wireless fidelity; Performance gain; Low latency communication | 5G mobile communication systems; Internet protocols; Wi-Fi; Wireless networks; 5g mobile communication; Connection migration; Delay; Hand over; Internet connection; IP-network; Mobile client; Mobile communications; Routings; Wireless/mobile networks; Table lookup | English | 2024 | 2024-04 | 10.1109/mcom.023.2300083 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Meeting Abstract | One-year clinical outcomes of switching to subcutaneous infliximab in patients with inflammatory bowel disease on maintenance of intravenous infliximab therapy with or without remission: A multicentre cohort study | Bae, J. H.; Park, J. B.; Baek, J. E.; Lee, Y. J.; Kim, K. O.; Kim, E. S.; Jo, H. H.; Hong, S. W.; Park, S. H.; Yang, D. H.; Ye, B. D.; Myung, S. J.; Yang, S. K.; Kim, E. Y.; Hwang, S. W. | Univ Ulsan, Coll Med, Asan Med Ctr, Dept Gastroenterol & Internal Med, Seoul, South Korea; Keimyung Univ, Sch Med, Dept Internal Med, Daegu, South Korea; CCAiD, Crohns & Colitis Assoc Daegu Gyeongbuk, Daegu, South Korea; Yeungnam Univ, Coll Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Daegu Catholic Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Inflammatory Bowel Dis Ctr, Seoul, South Korea | Myung, Sun-Jung/J-5464-2012 | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Meeting Abstract | One-year safety and effectiveness of ustekinumab in patients with Crohn's disease: The K-STAR study | Lee, C. K.; Moon, W.; Chun, J.; Kim, E. S.; Kim, H. W.; Yoon, H.; Kim, H. S.; Lee, Y. J.; Choi, C. H.; Jung, Y.; Park, S. C.; Song, G. A.; Lee, J. H.; Jung, E. S.; Kim, Y.; Jung, S. Y.; Choi, J. M.; Ye, B. D. | Kyung Hee Univ Hosp, Kyung Hee Univ Coll Med, Ctr Crohns & Colitis, Gastroenterol, Seoul, South Korea; Kosin Univ Coll Med, Internal Med, Busan, South Korea; Yonsei Univ Coll Med, Gangnam Severance Hosp, Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Internal Med, Daegu, South Korea; Pusan Natl Univ Yangsan Hosp, Internal Med, Busan, South Korea; Seoul Natl Univ Bundang Hosp, Internal Med, Seongnam, South Korea; Chonnam Univ Med Sch, Internal Med, Gwangju, South Korea; Keimyung Univ Sch Med, Internal Med, Daegu, South Korea; Chung Ang Univ, Internal Med, Coll Med, Seoul, South Korea; Soonchunhyang Univ Coll Med, Internal Med, Cheonan, South Korea; Kangwon Natl Univ, Sch Med, Gastroenterol & Hepatol Internal Med, Chunchon, South Korea; Pusan Natl Univ Coll Med, Internal Med, Busan, South Korea; Dong A Univ Med Ctr, Internal Med, Busan, South Korea; Janssen Korea Ltd, Med Affairs, Seoul, South Korea; Univ Ulsan Coll Med, Gastroenterol Inflammatory Bowel Dis Ctr, Asan Med Ctr, Seoul, South Korea | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 1 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | ○ | Article | Operator's Perspective on 6G: 6G Services, Vision, and Spectrum | 6G refers to the communication and services expected to emerge around 2030, coinciding with the convergence of service/terminal evolution and the evolution of mobile communication. Successful implementation of 6G necessitates collaborative efforts from all participants in emerging 6G ecosystems. This includes expanding the range of 6G usage scenarios, selecting appropriate candidate spectrum, and fostering open interfaces. Promising applications for 6G, such as artificial intelligence (AI), sensing, autonomous vehicles (AVs), urban air mobility (UAM), extended reality (XR), holograms, and digital twins, are under discussion. However, the identification of "killer services" unique to 6G and the development of innovative form factor devices are deemed crucial for delivering unprecedented customer experiences. This article reviews key lessons learned from the world's initial 5G commercialization, known as "5G Lessons Learned," and subsequently presents perspectives on 6G usage scenarios and services anticipated to be implemented by 2030. Notably, simultaneous exploration of new spectrum and refarming of underutilized spectrum in existing services are highlighted as imperative. As part of this initiative, we provide tangible measurement study results for high-frequency bands considered as potential 6G candidate spectrum. | Na, Minsoo; Lee, Jaehyun; Choi, Giwan; Yu, Takki; Choi, Jeongsik; Lee, Jinyoung; Bahk, Saewoong | SK Telecom Co Ltd, Seoul, South Korea; Kyungpook Natl Univ, Daegu, South Korea; Seoul Natl Univ, Seoul, South Korea | 56808918400; 56768488800; 35752864100; 9132768900; 58534394200; 59269755000; 55666882900 | IEEE COMMUNICATIONS MAGAZINE | IEEE COMMUN MAG | 0163-6804 | 1558-1896 | 62 | 8 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2024 | 8.2 | 7.8 | 4.14 | 2025-05-07 | 11 | 17 | 6G mobile communication; Wireless communication; Wireless sensor networks; 5G mobile communication; Extended reality; Standards organizations | Holograms; Unmanned aerial vehicles (UAV); Autonomous Vehicles; Commercialisation; Customer experience; Form factors; Mobile communications; Open Interface; Re-farming; Spectra's; Urban air; Usage scenarios; 5G mobile communication systems | English | 2024 | 2024-08 | 10.1109/mcom.001.2400060 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Post-symptomatic administration of hMSCs exerts therapeutic effects in SCA2 mice | BackgroundDefects in the ataxin-2 (ATXN-2) protein and CAG trinucleotide repeat expansion in its coding gene, Atxn-2, cause the neurodegenerative disorder spinocerebellar ataxia type 2 (SCA2). While clinical studies suggest potential benefits of human-derived mesenchymal stem cells (hMSCs) for treating various ataxias, the exact mechanisms underlying their therapeutic effects and interaction with host tissue to stimulate neurotrophin expression remain unclear specifically in the context of SCA2.MethodsHuman bone marrow-derived MSCs (hMSCs) were injected into the cisterna magna of 26-week-old wild-type and SCA2 mice. Mice were assessed for impaired motor coordination using the accelerating rotarod, open field test, and composite phenotype scoring. At 50 weeks, the cerebellum vermis was harvested for protein assessment and immunohistochemical analysis.ResultsSignificant loss of NeuN and calbindin was observed in 25-week-old SCA2 mice. However, after receiving multiple injections of hMSCs starting at 26 weeks of age, these mice exhibited a significant improvement in abnormal motor performance and a protective effect on Purkinje cells. This beneficial effect persisted until the mice reached 50 weeks of age, at which point they were sacrificed to study further mechanistic events triggered by the administration of hMSCs. Calbindin-positive cells in the Purkinje cell layer expressed bone-derived neurotrophic factor after hMSC administration, contributing to the protection of cerebellar neurons from cell death.ConclusionIn conclusion, repeated administration of hMSCs shows promise in alleviating SCA2 symptoms by preserving Purkinje cells, improving neurotrophic support, and reducing inflammation, ultimately leading to the preservation of locomotor function in SCA2 mice. | Kim, Sehwan; Sharma, Chanchal; Hong, Jungwan; Kim, Jong-Heon; Nam, Youngpyo; Kim, Min Sung; Lee, Tae Yong; Kim, Kyung-Suk; Suk, Kyoungho; Lee, Ho-Won; Kim, Sang Ryong | Kyungpook Natl Univ, Sch Life Sci & Biotechnol, BK21 FOUR KNU Creat Biores Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41566, South Korea; USF, Byrd Alzheimers Ctr & Res Inst, Tampa, FL 33620 USA; Corestemchemon Inc, Bioengn Inst, Seoul 13486, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol & Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Neurol, Daegu 41404, South Korea | 57193232250; 57193577728; 57196247899; 57203324811; 55143100300; 57218438989; 57205775062; 59082232900; 7005114595; 35337240700; 56486163800 | srk75@knu.ac.kr; | STEM CELL RESEARCH & THERAPY | STEM CELL RES THER | 1757-6512 | 15 | 1 | SCIE | CELL & TISSUE ENGINEERING;CELL BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL | 2024 | 7.3 | 7.8 | 0 | 2025-05-07 | 0 | 0 | Spinocerebellar ataxia type 2; Mesenchymal stem cells; Purkinje cells; Neurotrophic factor; Follistatin-like 1; Neuroinflammation | MESENCHYMAL STEM-CELLS; FOLLISTATIN-LIKE 1; NEUROTROPHIC FACTOR; SPINOCEREBELLAR ATAXIA; PURKINJE-CELLS; TRANSFORMING GROWTH-FACTOR-BETA-1; INFLAMMATORY RESPONSE; CEREBRAL-ISCHEMIA; STROMAL CELLS; MOUSE MODELS | Follistatin-like 1; Mesenchymal stem cells; Neuroinflammation; Neurotrophic factor; Purkinje cells; Spinocerebellar ataxia type 2 | Animals; Ataxin-2; Calbindins; Disease Models, Animal; DNA-Binding Proteins; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Purkinje Cells; Spinocerebellar Ataxias; apolipoprotein E; ataxin 2; brain derived neurotrophic factor; follistatin like 1; neurotrophin; peptides and proteins; unclassified drug; ataxin 2; calbindin; DNA binding protein; nerve protein; NeuN protein, mouse; animal cell; animal experiment; animal model; animal tissue; Article; cell death; cerebellum; cisterna magna; controlled study; exercise; female; flow cytometry; fluorescence microscopy; immunoblotting; immunofluorescence; male; mesenchymal stem cell; mouse; nerve cell; nervous system inflammation; nonhuman; open field test; polymerase chain reaction; protein expression; Purkinje cell; rotarod test; signal transduction; Western blotting; animal; cytology; disease model; genetics; human; mesenchymal stem cell; mesenchymal stem cell transplantation; metabolism; motor activity; pathology; procedures; spinocerebellar degeneration; therapy; transgenic mouse | English | 2024 | 2024-11-09 | 10.1186/s13287-024-04020-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Meeting Abstract | Predicted inflammatory status and Inflammatory Bowel Disease among Korean adults: a Multicentre case-control study | Kim, D. H.; Okekunle, A. P.; Kang, J.; Kim, H. S.; Kim, S. H.; Jung, M. K.; Park, J. H.; Na, S. Y.; Lee, J. E.; Lim, Y. J.; Chun, H. | Chonnam Natl Univ Hosp, Dept Internal Med, Div Gastroenterol, Gwangju, South Korea; Seoul Natl Univ, Dept Food & Nutr, Coll Human Ecol, Seoul, South Korea; Chung Ang Univ, Dept Internal Med, Gwangmyeong Hosp, Div Gastroenterol, Gwangmyeong, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Gastroenterol, Daegu, South Korea; Chungnam Natl Univ, Dept Internal Med, Sejong Hosp, Div Gastroenterol, Sejong, South Korea; Catholic Univ Korea, Dept Internal Med, Incheon St Marys Hosp, Div Gastroenterol,Coll Med, Incheon, South Korea; Dongguk Univ, Dept Internal Med, Div Gastroenterol, Ilsan Hosp,Coll Med, Goyang, South Korea; Korea Univ Hosp, Seoul, South Korea; Korea Univ, Dept Internal Med, Coll Med, Div Gastroenterol, Seoul, South Korea | Lee, Jung/AAC-5634-2020; Okekunle, Akinkunmi/AAC-9804-2020 | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Meeting Abstract | Real-life effectiveness and safety of ustekinumab treatment in patients with ulcerative colitis: An Asan-Crohn's and Colitis Association in Daegu-Gyeongbuk (CCAiD) multicenter cohort study | Baek, J. E.; Kim, E. S.; Kim, K. O.; Jo, H. H.; Hwang, S. W.; Park, S. H.; Jang, B. I.; Kim, E. Y.; Yang, S. K.; Kim, S. K.; Ye, B. D. | Univ Ulsan, Coll Med, Asan Med Ctr, Dept Gastroenterol, Seoul, South Korea; Kyungpook Natl Univ, Dept Internal Med, Sch Med, Daegu, South Korea; Yeungnam Univ, Coll Med, Dept Internal Med, Daegu, South Korea; Daegu Catholic Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Inflammatory Bowel Dis Ctr, Seoul, South Korea | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | Meeting Abstract | Risk of Infection After Acute Severe Ulcerative Colitis in East Asia and Australia/New Zealand: AOCC and ANZIBDC collaboration study | Kim, S. J.; Kim, D. H.; Park, S. H.; Kim, K. O.; Lee, Y. J.; Song, E. M.; Kim, E. S.; Lee, H. S.; An, Y. K.; Begun, J.; Ruddick-Collins, L.; Fernandes, R.; Liu, J.; Cao, Q.; Kobayashi, T.; Wei, S. C. | Chosun Univ Hosp, Div Gastroenterol, Dept Internal Med, Gwangju, South Korea; Chonnam Natl Univ, Div Gastroenterol, Dept Internal Med, Gwangju, South Korea; Korean Assoc Study Intestinal Dis, IBD Res Grp, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Gastroenterol, Seoul, South Korea; Ctr Inflammatory Bowel Dis, Seoul, South Korea; Yeungnam Univ Hosp, Div Gastroenterol, Dept Internal Med, Daegu, South Korea; Keimyung Univ Hosp, Div Gastroenterol, Dept Internal Med, Daegu, South Korea; Ewha Womans Univ, Div Gastroenterol, Seoul Hosp, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ Hosp, Div Gastroenterol, Dept Internal Med, Daegu, South Korea; Mater Hosp, Dept Gastroenterol, Brisbane, Qld, Australia; ANZIBDC, Australia New Zealand IBD Consortium, Brisbane, Qld, Australia; Univ Queensland, Mater Res Inst, Brisbane, Qld, Australia; Zhejiang Chinese Med Univ, Sch Life Sci, Hangzhou, Peoples R China; Kitasato Univ, Kitasato Inst Hosp, Ctr Adv IBD Res & Treatment, Tokyo, Japan; Natl Taiwan Univ, Dept Internal Med, Natl Taiwan Univ Hosp, Taipei, Taiwan | JOURNAL OF CROHNS & COLITIS | J CROHNS COLITIS | 1873-9946 | 1876-4479 | 18 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 8.7 | 7.8 | 0 | English | 2024 | 2024-01 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | ○ | Article | Simple modeling of familial Alzheimer's disease using human pluripotent stem cell-derived cerebral organoid technology | Background Cerebral organoids (COs) are the most advanced in vitro models that resemble the human brain. The use of COs as a model for Alzheimer's disease (AD), as well as other brain diseases, has recently gained attention. This study aimed to develop a human AD CO model using normal human pluripotent stem cells (hPSCs) that recapitulates the pathological phenotypes of AD and to determine the usefulness of this model for drug screening.Methods We established AD hPSC lines from normal hPSCs by introducing genes that harbor familial AD mutations, and the COs were generated using these hPSC lines. The pathological features of AD, including extensive amyloid-beta (A beta) accumulation, tauopathy, and neurodegeneration, were analyzed using enzyme-linked immunosorbent assay, Amylo-Glo staining, thioflavin-S staining, immunohistochemistry, Bielschowsky's staining, and western blot analysis.Results The AD COs exhibited extensive A beta accumulation. The levels of paired helical filament tau and neurofibrillary tangle-like silver deposits were highly increased in the AD COs. The number of cells immunoreactive for cleaved caspase-3 was significantly increased in the AD COs. In addition, treatment of AD COs with BACE1 inhibitor IV, a beta-secretase inhibitor, and compound E, a gamma-secretase inhibitor, significantly attenuated the AD pathological features.Conclusion Our model effectively recapitulates AD pathology. Hence, it is a valuable platform for understanding the mechanisms underlying AD pathogenesis and can be used to test the efficacy of anti-AD drugs. | Choe, Mu Seog; Yeo, Han Cheol; Kim, Joong Sun; Lee, Jean; Lee, Hae Jun; Kim, Hyung-Ryong; Baek, Kyung Min; Jung, Na-Yeon; Choi, Murim; Lee, Min Young | Kyungpook Natl Univ, Vessel Organ Interact Res Ctr VOICE, MRC, Dept Mol Physiol,Coll Pharm,Res Inst Pharmaceut Sc, Daegu 41566, South Korea; Chonnam Natl Univ, Coll Vet Med, Dept Vet Anat, Gwangju 61186, South Korea; Seoul Natl Univ, Coll Med, Dept Biochem & Biomed Sci, Seoul 03080, South Korea; Korea Inst Radiol & Med Sci KIRAMS, Div Radiat Biomed Res, Seoul 01812, South Korea; Jeonbuk Natl Univ, Coll Dent, Dept Pharmacol, Jeonju 54896, South Korea; Daegu Haany Univ, Coll Oriental Med, Dept Cardiovasc & Neurol Dis, Daegu 42158, South Korea; Pusan Natl Univ, Sch Med, Dept Neurol, Yangsan Hosp, Yangsan 50612, South Korea | ; Kim, Hyunggee/F-2673-2013; Choi, Murim/AAP-9120-2021 | 57202926165; 57202931191; 7601371367; 57214361751; 58641054400; 57223656110; 56421484100; 57210822123; 36929149400; 15119890400 | murimchoi@snu.ac.kr;vetmedic@knu.ac.kr; | STEM CELL RESEARCH & THERAPY | STEM CELL RES THER | 1757-6512 | 15 | 1 | SCIE | CELL & TISSUE ENGINEERING;CELL BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL | 2024 | 7.3 | 7.8 | 5.22 | 2025-05-07 | 13 | 14 | Cerebral organoids; Human pluripotent stem cells; Alzheimer's disease; Disease modeling; Drug screening | HELICAL FILAMENT-TAU; A-BETA; DIFFERENTIATION; NEURONS; PROTEIN | Alzheimer’s disease; Cerebral organoids; Disease modeling; Drug screening; Human pluripotent stem cells | Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Brain; Humans; Models, Biological; Organoids; Pluripotent Stem Cells; tau Proteins; amyloid beta protein; amyloid precursor protein; beta secretase 1; beta secretase inhibitor; caspase 3; fibroblast growth factor 2; gamma secretase inhibitor; presenilin 1; RNA; amyloid beta protein; aspartic proteinase; BACE1 protein, human; secretase; tau protein; adult; Alzheimer disease; Article; Bielschowsky staining; cerebral organoid; controlled study; environmental factor; enzyme linked immunosorbent assay; female; flow cytometry; gene mutation; heredity; human; immunocytochemistry; immunohistochemistry; immunoreactivity; mouse; nerve cell differentiation; nerve degeneration; neurofibrillary tangle; nonhuman; pathogenesis; phenotype; pluripotent stem cell; protein cleavage; protein phosphorylation; RNA sequencing; staining; tauopathy; thioflavin S staining; Western blotting; whole genome sequencing; Alzheimer disease; biological model; brain; genetics; metabolism; organoid; pathology | English | 2024 | 2024-04-24 | 10.1186/s13287-024-03732-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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