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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Enhanced thermochemical valorization of coconut husk through carbon dioxide integration: A sustainable approach to agricultural residue utilization | In this study, we aimed to develop a sustainable valorization platform for agricultural residues, mainly focusing on harnessing these residues as a renewable energy source. We conducted a case study involving the pyrolysis of coconut husk to create a sustainable pathway for its valorization. To enhance environmental compatibility, carbon dioxide (CO2) was employed as the reaction medium. CO2 acted as a partial oxidant, leading to the oxidation of carbons in the bio-oil and the formation of carbon monoxide (CO). In detail, this study experimentally proved the mechanistic contribution of CO2 to shifting carbon in pyrogenic oil into gases, particularly CO. To enhance the reactivity of CO2, the catalytic pyrolysis of coconut husk was conducted using a nickel-based egg-shell-type (Ni-ES) catalyst. Catalyst introduction resulted in the increased concentration of syngas compared with conditions without a catalyst in the presence of CO2. In particular, syngas production from catalytic pyrolysis under CO2 conditions was enhanced by >6.5-fold compared with that from single-stage pyrolysis under N-2 conditions. Simultaneously, the evolution of pyrogenic oil was significantly reduced under CO2 condition in the presence of the Ni-ES catalyst. This confirms the catalytic potential in further optimizing the valorization of agricultural residues for sustainable energy production. | Kwon, Dohee; Kim, Youngju; Choi, Dongho; Jung, Sungyup; Tsang, Yiu Fai; Kwon, Eilhann E. | Hanyang Univ, Dept Earth Resources & Environm Engn, Seoul 04763, South Korea; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Educ Univ Hong Kong, Dept Sci & Environm Studies, Tai Po, Hong Kong 999077, Peoples R China | ; Jung, Sungyup/GZG-6207-2022; Kwon, Eilhann/AGY-3339-2022; Tsang, Yiu/AAJ-2524-2020; Choi, Dongho/LTY-8225-2024 | 57208275497; 58662374200; 57200013497; 55073290800; 22954605700; 9240622100 | ek2148@hanyang.ac.kr; | APPLIED ENERGY | APPL ENERG | 0306-2619 | 1872-9118 | 369 | SCIE | ENERGY & FUELS;ENGINEERING, CHEMICAL | 2024 | 11 | 6.6 | 1.18 | 2025-05-07 | 5 | 5 | Waste-to-energy; Waste valorization; Circular economy; Agricultural waste; Thermo-chemical process; CO2 utilization | RENEWABLE ENERGY; FAST PYROLYSIS; BIO-FUELS; BIOMASS; WASTE; CO2; BIOCHAR; CONVERSION; BIOFUELS; CATALYST | Agricultural waste; Circular economy; CO<sub>2</sub> utilization; Thermo-chemical process; Waste valorization; Waste-to-energy | Agricultural wastes; Agriculture; Carbon dioxide; Catalysts; Pyrolysis; Renewable energy; Syngas production; Synthesis gas; Carbon monoxide2 utilization; Catalytic pyrolysis; Circular economy; Coconut husk; Condition; Egg shells; Thermo chemical process; Valorisation; Waste to energy; Waste valorizations; alternative energy; biofuel; carbon dioxide; carbon monoxide; chemical process; crop residue; economic system; oxidation; pyrolysis; valorization; Carbon monoxide | English | 2024 | 2024-09-01 | 10.1016/j.apenergy.2024.123576 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Generative artificial intelligence and building design: early photorealistic render visualization of façades using local identity-trained models | This paper elucidates an approach that utilizes generative artificial intelligence (AI) to develop alternative architectural design options based on local identity. The advancement of AI technologies has increasingly piqued the interest of the architecture, engineering, construction, and facility management industry. Notably, the topic of "visualization" has gained prominence as a means for enhancing communication related to a project, especially in the early phases of design. This study aims to enhance the ease of obtaining design images during initial phases of design by drawing from multiple texts and images. It develops an additional training model to generate various design alternatives that resonate with the identity of the locale through the application of generative AI to the facade design of buildings. The identity of a locality in cities and regions is the capacity for the cities and regions to be identified and recognized as a specific area. Among the various visual elements of urban and regional landscapes, the front face of buildings may play a significant role in people's aesthetic perception and overall impression of the local environment. The research proposes an approach that transcends the conventional employment of three-dimensional modeling and rendering tools by readily deriving design alternatives that consider this local identity in commercial building remodeling. This approach allows for financial and temporal efficiency in the design communication phase of the initial architectural design process. The implementation and utilization of the proposed approach's supplementary training model in this study proceeds as follows: (i) image data are collected from the target area using open-source street-view resources and preprocessed for conversion to a trainable format; (ii) textual data are prepared for pairing with preprocessed image data; (iii) additional training and outcome testing are performed using varied text prompts and images; and (iv) the ability to generate building facade images that reflect the identity of the collected locale by using the additional trained model is determined, as evidenced by the findings of the proposed application method study. This enables the generation of design alternatives that integrate regional styles and diverse design requirements for buildings. The training model implemented in this study can be leveraged through weight adjustments and prompt engineering to generate a greater number of design reference images, among other diverse approaches. Graphical Abstract | Jo, Hayoung; Lee, Jin-Kook; Lee, Yong-Cheol; Choo, Seungyeon | Yonsei Univ, Dept Interior Architecture & Built Environm, Seoul 03722, South Korea; Louisiana State Univ, Baton Rouge, LA 70803 USA; Kyungpook Natl Univ, Daegu 41566, South Korea | ; Choo, Seungyeon/JFB-0390-2023 | 59079439400; 57201264374; 56402166700; 36835366900 | leejinkook@yonsei.ac.kr; | JOURNAL OF COMPUTATIONAL DESIGN AND ENGINEERING | J COMPUT DES ENG | 2288-5048 | 11 | 2 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, MULTIDISCIPLINARY | 2024 | 6.1 | 6.6 | 9.23 | 2025-05-07 | 22 | 25 | architectural design; design visualization; generative artificial intelligence; additional training model; diffusion model; image generation; facade design | REPRESENTATION; ARCHITECTURE; REALITY; CAD; BIM | additional training model; architectural design; design visualization; diffusion model; façade design; generative artificial intelligence; image generation | Artificial intelligence; Office buildings; Rendering (computer graphics); Three dimensional computer graphics; Visualization; Additional training model; Building design; Design alternatives; Design visualization; Diffusion model; Facade design; Generative artificial intelligence; Image data; Image generations; Training model; architectural design; artificial intelligence; building construction; data set; employment; image analysis; perception; three-dimensional modeling; visualization; Architectural design | English | 2024 | 2024-03-06 | 10.1093/jcde/qwae017 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Industrial defective chips detection using deep convolutional neural network with inverse feature matching mechanism | The growing demand for high-quality industrial products has led to a significant emphasis on image anomaly detection (AD). AD in industrial goods presents a formidable research challenge that demands the application of sophisticated techniques to identify and address deviations from the expected norm accurately. Manufacturers increasingly recognize the significance of employing intelligent systems to detect flaws and defects in product parts. However, industrial settings pose several challenges: diverse categories, limited abnormal samples and vagueness. Hence, there is a growing demand for advanced image AD techniques within industrial product manufacturing. In this paper, an intelligent industrial defective chips detection framework is proposed which mainly consists of three core components. First, the convolutional features of the efficient backbone model is effectively utilized to balance the computational complexity and performance of industrial resource-constrained devices. Secondly, a novel inverse feature matching followed by masking method is proposed to enhance the explanability that localizes the abnormal regions of the abnormal chips. Finally, to evaluate our proposed method a comprehensive ablation study is conducted, where different machine learning and deep learning algorithms are analysed to claim the superiority of our method. Furthermore, to help the research community, a benchmark dataset is collected from real-world industry manufacturing for defective chip detection. The empirical results from the dataset demonstrate the strength and effectiveness of the proposed model compared to the other models. Graphical Abstract The framework processes images to highlight defects using thresholding, improving visualization, and thereby enhancing product quality, cost efficiency, and customer satisfaction in manufacturing. | Ullah, Waseem; Khan, Samee Ullah; Kim, Min Je; Hussain, Altaf; Munsif, Muhammad; Lee, Mi Young; Seo, Daeho; Baik, Sung Wook | Sejong Univ, Seoul 143747, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Chung Ang Univ, 84 Heukseok Ro, Seoul 06974, South Korea; Dagyeom Co, Seoul, South Korea | ; Lee, Mi-Young/AAE-9946-2020; Baik, Sung/ABC-3969-2022; Khan, Samee/AAA-3302-2019; HUSSAIN, ALTAF/JCN-7515-2023; ULLAH, Waseem/ABE-6599-2021; Munsif, Muhammad/GOG-7862-2022 | 57218579944; 59045429700; 58024667500; 57212425772; 57223915612; 55902262800; 59175516400; 7102833923 | sbaik@sejong.ac.kr; | JOURNAL OF COMPUTATIONAL DESIGN AND ENGINEERING | J COMPUT DES ENG | 2288-5048 | 11 | 3 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, MULTIDISCIPLINARY | 2024 | 6.1 | 6.6 | 1.94 | 2025-05-07 | 7 | 8 | industrial anomaly detection; image processing; features engineering; deep learning; convolutional neural network | ANOMALY DETECTION; FAULT | convolutional neural network; deep learning; features engineering; image processing; industrial anomaly detection | Anomaly detection; Convolution; Convolutional neural networks; Deep neural networks; Feature extraction; Image processing; Industrial research; Inverse problems; Learning algorithms; Learning systems; Anomaly detection; Convolutional neural network; Deep learning; Defective chips; Feature engineerings; Features matching; Growing demand; Images processing; Industrial anomaly detection; Industrial product; artificial neural network; detection method; image processing; machine learning; Intelligent systems | English | 2024 | 2024-06-14 | 10.1093/jcde/qwae019 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Korean clinical practice guidelines for diagnostic and procedural sedation | Safe and effective sedation depends on various factors, such as the choice of sedatives, sedation techniques used, experience of the sedation provider, degree of sedation -related education and training, equipment and healthcare worker availability, the patient's underlying diseases, and the procedure being performed. The purpose of these evidence -based multidisciplinary clinical practice guidelines is to ensure the safety and efficacy of sedation, thereby contributing to patient safety and ultimately improving public health. These clinical practice guidelines comprise 15 key questions covering various topics related to the following: the sedation providers; medications and equipment available; appropriate patient selection; anesthesiologist referrals for high -risk patients; pre -sedation fasting; comparison of representative drugs used in adult and pediatric patients; respiratory system, cardiovascular system, and sedation depth monitoring during sedation; management of respiratory complications during pediatric sedation; and discharge criteria. The recommendations in these clinical practice guidelines were systematically developed to assist providers and patients in sedation -related decision making for diagnostic and therapeutic examinations or procedures. Depending on the characteristics of primary, secondary, and tertiary care institutions as well as the clinical needs and limitations, sedation providers at each medical institution may choose to apply the recommendations as they are, modify them appropriately, or reject them completely. | Kim, Sang-Hyun; Moon, Young-Jin; Chae, Min Suk; Lee, Yea-Ji; Karm, Myong-Hwan; Joo, Eun-Young; Min, Jeong-Jin; Koo, Bon-Nyeo; Choi, Jeong-Hyun; Hwang, Jin-Young; Yang, Yeonmi; Kwon, Min A.; Koh, Hyun Jung; Kim, Jong Yeop; Park, Sun Young; Kim, Hyunjee; Chung, Yang-Hoon; Kim, Na Young; Choi, Sung Uk | Soonchunhyang Univ, Coll Med, Dept Anesthesiol & Pain Med, Bucheon Hosp, Bucheon, South Korea; Univ Ulsan, Asan Med Ctr, Coll Med, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Seoul, South Korea; Konkuk Univ, Med Ctr, Seoul, South Korea; Seoul Natl Univ, Sch Dent, Dept Dent Anesthesiol, Seoul, South Korea; Seoul Natl Univ, Dent Res Inst, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Anesthesiol & Pain Med, Sch Med, Seoul, South Korea; Yonsei Univ, Anesthesia & Pain Res Inst, Coll Med, Seoul, South Korea; Kyung Hee Univ, Coll Med, Seoul, South Korea; Seoul Natl Univ, Coll Med, SMG SNU Boramae Med Ctr, Seoul, South Korea; Jeonbuk Natl Univ, Dept Pediat Dent, Sch Dent, Jeonju, South Korea; Dankook Univ Hosp, Dept Anesthesiol & Pain Med, Cheonan, South Korea; Ajou Univ, Sch Med, Suwon, South Korea; Soonchunhyang Univ, Seoul Hosp, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Korea Univ, Coll Med, Seoul, South Korea; Kyung Hee Univ Hosp, Dept Anesthesiol & Pain Med, 23 Kyungheedae Ro, Seoul 02447, South Korea | Choi, Jeong-Hyun/AAI-1864-2020; Choi, Sung-Uk/G-8547-2012; Chung, Yang Hoon/HII-9418-2022; Karm, Myong-Hwan/M-1994-2016; Kim, Na/A-8115-2008; Kim, Dong/F-4608-2014; koo, bonnyeo/AAW-1415-2021 | 57204708870; 55992739900; 57191608099; 56972766700; 55585044300; 37861540100; 36627464200; 7101737664; 56923889600; 7403896985; 36053902200; 26637745100; 9745877300; 57214362661; 57194242586; 57208674365; 57204056364; 56692998000; 55808351600 | cjh@khu.ac.kr; | KOREAN JOURNAL OF ANESTHESIOLOGY | KOREAN J ANESTHESIOL | 2005-6419 | 2005-7563 | 77 | 1 | SCIE | ANESTHESIOLOGY | 2024 | 6.3 | 6.6 | 2.3 | 2025-05-07 | 6 | 5 | Anesthesiologist; Capnography; Clinical practice guideline; Fasting; Patient monitoring; Procedural sedation; Recovery | ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; PROPOFOL SEDATION; EMERGENCY-DEPARTMENT; CONSCIOUS SEDATION; OXYGEN DESATURATION; CHLORAL HYDRATE; ADVERSE EVENTS; ORAL MIDAZOLAM; DOUBLE-BLIND; PEDIATRIC SEDATION/ANESTHESIA | Anesthesiologist; Capnography; Clinical practice guideline; Fasting; Patient monitoring; Procedural sedation; Recovery | Adult; Anesthesia; Child; Conscious Sedation; Humans; Hypnotics and Sedatives; Patient Safety; Republic of Korea; chloral hydrate; dexmedetomidine; ketamine; midazolam; propofol; hypnotic sedative agent; anesthesiologist; capnometry; cardiovascular system; clinical practice; decision making; dyspnea; education; electrocardiography; fasting; health care personnel; high risk patient; human; hypoxemia; Korean (people); oxygen saturation; patient monitoring; patient safety; pediatric patient; practice guideline; public health; Review; sedation; adult; anesthesia; child; conscious sedation; South Korea | English | 2024 | 2024-02 | 10.4097/kja.23745 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Micro(nano)plastics from synthetic oligomers persisting in Mediterranean seawater: Comprehensive NMR analysis, concerns and origins | The presence in seawater of low-molecular-weight polyethylene (PE) and polydimethylsiloxane (PDMS), synthetic polymers with high chemical resistance, has been demonstrated in this study for the first time by developing a novel methodology for their recovery and quantification from surface seawater. These synthetic polymer debris (SPD) with very low molecular weights and sizes in the nano- and micro-metre range have escaped conventional analytical methods. SPD have been easily recovered from water samples (2 L) through filtration with a nitrocellulose membrane filter with a pore size of 0.45 mu m. Dissolving the filter in acetone allowed the isolation of the particulates by centrifugation followed by drying. The isolated SPD were analysed by 1H nuclear magnetic resonance spectroscopy (1H NMR), identifying PE and PDMS. These polymers are thus persisting on seawater because of their low density and the ponderal concentrations were quantified in mg/m3. This method was used in an actual case study in which 120 surface seawater samples were collected during two sampling campaigns in the Mediterranean Sea (from the Gulf of Salerno to the Gulf of Policastro in South Italy). The developed analytical protocol allowed achieving unprecedented simplicity, rapidity and sensitivity. The 1H and 13C NMR structural analysis of the PE debris indicates the presence of oxidised polymer chains with very low molecular weights. Additionally, the origin of those low molecular weight polymers was investigated by analysing influents and effluents from a wastewater treatment plant (WWTP) in Salerno as a hot spot for the release of SPD: the analysis indicates the presence of low molecular weight polymers compatible with wax-PE, widely used for coating applications, food industry, cosmetics and detergents. Moreover, the origin of PDMS debris found in surface seawater can be ascribed to silicone-based antifoamers and emulsifiers. | Giannattasio, Alessia; Iuliano, Veronica; Oliva, Giuseppina; Giaquinto, Domenico; Capacchione, Carmine; Cuomo, Maria Teresa; Hasan, Shadi W.; Choo, Kwang-Ho; Korshin, Gregory V.; Barcelo, Damia; Belgiorno, Vincenzo; Grassi, Alfonso; Naddeo, Vincenzo; Buonerba, Antonio | Univ Salerno, Dept Chem & Biol Adolfo Zambelli, Via Giovanni Paolo 2, I-84084 Fisciano, SA, Italy; Univ Salerno, Sanit Environm Engn Div SEED, Dept Civil Engn, Via Giovanni Paolo 2, I-84084 Fisciano, SA, Italy; Univ Salerno, Dept Econ & Stat, Via Giovanni Paolo 2, I-84084 Fisciano, Italy; Khalifa Univ Sci & Technol, Ctr Membranes & Adv Water Technol CMAT, Dept Chem & Petr Engn, POB 127788, Abu Dhabi, U Arab Emirates; Kyungpook Natl Univ, Dept Environm Engn, 80 Daehakro, Daegu 41566, South Korea; Univ Washington, Dept Civil & Environm Engn, Box 352700, Seattle, WA 98105 USA; Univ Almeria, Chem & Phys Dept, Ctra Sacramento S-N, Almeria 04120, Spain | Choo, Kwang-Ho/A-3456-2016; Cuomo, Maria T/C-2513-2013; Oliva, Giuseppina/ABR-8569-2022; Capacchione, Carmine/AAC-5916-2020; Naddeo, Vincenzo/C-4057-2008; BARCELO, DAMIA/O-4558-2016; Buonerba, Antonio/C-3112-2013 | 57223920485; 57192115998; 20735093300; 59967143000; 6603437257; 16024021300; 35738779100; 7102083272; 7003696629; 36013249500; 6508019638; 7102772375; 57225215311; 36670901300 | vnaddeo@unisa.it;abuonerba@unisa.it; | ENVIRONMENT INTERNATIONAL | ENVIRON INT | 0160-4120 | 1873-6750 | 190 | SCIE | ENVIRONMENTAL SCIENCES | 2024 | 9.7 | 6.6 | 2.41 | 2025-05-07 | 9 | 9 | Microplastics; Nanoplastics; Recovery; Seawater; Marine; Quantification; Microfiltration; NMR spectroscopy; Standard method | NUCLEAR-MAGNETIC-RESONANCE; QUANTITATIVE H-1-NMR SPECTROSCOPY; MARINE ORGANISMS; MICROPLASTICS; IDENTIFICATION; PARTICLES; WATER; COPOLYMERIZATION; QUANTIFICATION; SULFONATION | Marine; Microfiltration; Microplastics; Nanoplastics; NMR spectroscopy; Quantification; Recovery; Seawater; Standard method | Dimethylpolysiloxanes; Environmental Monitoring; Magnetic Resonance Spectroscopy; Mediterranean Sea; Plastics; Polyethylene; Polymers; Seawater; Water Pollutants, Chemical; Gulf of Salerno; Italy; Mediterranean Sea; Tyrrhenian Sea; Acetone; Debris; Effluent treatment; Effluents; Microchannels; Microfiltration; Molecular weight; Polydimethylsiloxane; Pore size; Recovery; Seawater; Silicones; Soaps (detergents); Wastewater treatment; Water filtration; dimeticone; microplastic; nanoplastic; oligomer; polyethylene; polymer; silicone; plastic; polyethylene; polymer; sea water; Low molecular weight; Low-molecular-weight polymers; Marine; Microplastics; Nanoplastics; NMR-spectroscopy; Quantification; Standard method; Surface seawater; Synthetic polymers; filtration; nanoparticle; nuclear magnetic resonance; plastic waste; polymer; spectroscopy; wastewater treatment plant; analytic method; Article; Fourier transform infrared spectroscopy; Mediterranean Sea; microfiltration; nuclear magnetic resonance spectroscopy; proton nuclear magnetic resonance; waste water treatment plant; chemistry; environmental monitoring; Mediterranean Sea; procedures; water pollutant; Nuclear magnetic resonance spectroscopy | English | 2024 | 2024-08 | 10.1016/j.envint.2024.108839 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Multi-Objective Evolutionary Hybrid Deep Learning for energy theft detection | Electricity theft has emerged as a notable concern for smart grids, as fraudulent users illicitly access electricity from utilities without a contractual agreement or manipulate meter readings to evade bill payments. Consequently, the importance of electricity theft detection (ETD) in preserving the cost-effectiveness of smart grids has increased. In recent years, the utilization of deep learning models in electricity theft detection has surged in popularity, owing to their capacity to capture the periodic patterns within time -series data on electricity consumption. Nonetheless, deep learning techniques for electricity theft detection encounter several challenges, such as data imbalance, higher false positive rates, and the determination of periodic cycle timings. In this paper, we present an innovative approach to tackle these challenges: the Multi-Objective Evolutionary Hybrid Deep Learning (MOE-HDL) architecture, specifically designed to identify electricity theft. In MOEHDL techniques, first, a novel multi-objective evolutionary algorithm based on ranking scheme (RMOE) is proposed to optimize architectural model parameters and the detection window size, with precision and recall as conflicting objectives. Next, an optimized dynamic detection window is generated to effectively capture the periodic patterns in consumption data and convert the one -dimensional data into a grid structure. Finally, a hybrid deep learning model is designed with the help of optimized model parameters to identify abnormal patterns in electricity consumption data. We conducted a comprehensive set of experiments, comparing our approach with eight baseline methods for electricity theft detection. The experimental results demonstrate that the proposed MOE-HDL approach outperforms these alternatives in terms of performance. | Tursunboev, Jamshid; Palakonda, Vikas; Kang, Jae-Mo | Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu, South Korea | 57410135900; 57193028485; 56024930400 | jamshid@knu.ac.kr;vikas.11475@gmail.com;jmkang@knu.ac.kr; | APPLIED ENERGY | APPL ENERG | 0306-2619 | 1872-9118 | 363 | SCIE | ENERGY & FUELS;ENGINEERING, CHEMICAL | 2024 | 11 | 6.6 | 1.18 | 2025-05-07 | 3 | 5 | Electricity theft detection; Smart grid; Multi-objective optimization; Evolutionary deep learning | ELECTRICITY THEFT; STATE ESTIMATION; LOSSES; NETWORKS | Electricity theft detection; Evolutionary deep learning; Multi-objective optimization; Smart grid | Crime; Data handling; Deep learning; Electric power utilization; Evolutionary algorithms; Learning systems; Multiobjective optimization; Smart power grids; Electricity theft; Electricity theft detection; Electricity-consumption; Evolutionary deep learning; Learning models; Learning techniques; Multi-objective evolutionary; Multi-objectives optimization; Periodic pattern; Smart grid; algorithm; detection method; experimental study; fuel consumption; machine learning; optimization; performance assessment; precision; smart grid; Cost effectiveness | English | 2024 | 2024-06-01 | 10.1016/j.apenergy.2024.122847 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Poracle: Testing Patches under Preservation Conditions to Combat the Overfitting Problem of Program Repair | To date, the users of test-driven program repair tools suffer from the overfitting problem; a generated patch may pass all available tests without being correct. In the existing work, users are treated as merely passive consumers of the tests. However, what if they are willing to modify the test to better assess the patches obtained from a repair tool? In this work, we propose a novel semi-automatic patch-classification methodology named Poracle. Our key contributions are three-fold. First, we design a novel lightweight specification method that reuses the existing test. Specifically, the users extend the existing failing test with a preservation condition-the condition under which the patched and pre-patched versions should produce the same output. Second, we develop a fuzzer that performs differential fuzzing with a test containing a preservation condition. Once we find an input that satisfies a specified preservation condition but produces different outputs between the patched and pre-patched versions, we classify the patch as incorrect with high confidence. We show that our approach is more effective than the four state-of-the-art patch classification approaches. Last, we show through a user study that the users find our semi-automatic patch assessment method more effective and preferable than the manual assessment. | Ismayilzada, Elkhan; Rahman, Md Mazba Ur; Kim, Dongsun; Yi, Jooyong | UNIST, Dept Comp Sci, 50 UNIST Gil, Ulsan 44919, South Korea; Kyungpook Natl Univ, Daegu, South Korea | Rahman, Md Motiur/E-2419-2019; Kim, Dongsun/B-4856-2015 | elkhan@unist.ac.kr;mazbaur@unist.ac.kr;darkrsw@knu.ac.kr;jooyong@unist.ac.kr; | ACM TRANSACTIONS ON SOFTWARE ENGINEERING AND METHODOLOGY | ACM T SOFTW ENG METH | 1049-331X | 1557-7392 | 33 | 2 | SCIE | COMPUTER SCIENCE, SOFTWARE ENGINEERING | 2024 | 6.2 | 6.6 | 4 | Automated program repair; overfitting problem; patch validation; patch classification; preservation condition | GENERATION | English | 2024 | 2024-02 | 10.1145/3625293 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Targeting the Hippo pathway in Schwann cells ameliorates peripheral nerve degeneration via a polypharmacological mechanism | Peripheral neuropathies (PNs) are common diseases in elderly individuals characterized by Schwann cell (SC) dysfunction and irreversible Wallerian degeneration (WD). Although the molecular mechanisms of PN onset and progression have been widely studied, therapeutic opportunities remain limited. In this study, we investigated the pharmacological inhibition of Mammalian Ste20-like kinase 1/2 (MST1/2) by using its chemical inhibitor, XMUMP-1 (XMU), against WD. XMU treatment suppressed the proliferation, dedifferentiation, and demyelination of SCs in models of WD in vitro, in vivo, and ex vivo. As a downstream mediator of canonical and noncanonical Hippo/ MST1 pathway activation, the mature microRNA (miRNA) let-7b and its binding partners quaking homolog (QKI)/nucleolin (NCL) modulated miRNA-mediated silencing of genes involved in protein transport. Hence, direct phosphorylation of QKI and NCL by MST1 might be critical for WD onset and pathogenesis. Moreover, p38 alpha/ mitogen-activated protein kinase 14 (p38 alpha) showed a strong affinity for XMU, and therefore, it may be an alternative XMU target for controlling WD in SCs. Taken together, our findings provide new insights into the Hippo/MST pathway function in PNs and suggest that XMU is a novel multitargeted therapeutic for elderly individuals with PNs. | Chung, Hyung-Joo; Nguyen, Thy N. C.; Lee, Ji Won; Huh, Youngbuhm; Ko, Seungbeom; Lim, Heejin; Seo, Hyewon; Ha, Young-Geun; Chang, Jeong Ho; Woo, Jae-Sung; Song, Ji-Joon; Kim, So-Woon; Lee, Jin San; Mo, Jung-Soon; Park, Boyoun; Min, Kyung-Won; Yoon, Je-Hyun; Kim, Min-Sik; Jung, Junyang; Jeong, Na Young | Kosin Univ, Coll Med, Dept Anesthesiol & Pain Med, Busan 49267, South Korea; Daegu Gyeongbuk Inst Sci & Technol DGIST, Dept New Biol, Daegu 42988, South Korea; Gangneung Wonju Natl Univ, Coll Nat Sci, Dept Biol, Kangnung 25457, South Korea; Kyung Hee Univ, Coll Med, Dept Anat & Neurobiol, Seoul 02447, South Korea; Med Univ South Carolina, Dept Biochem & Mol Biol, Charleston, SC 29425 USA; Korea Basic Sci Inst KBSI, Ctr Sci Instrumentat, Cheongju 28119, South Korea; Daegu Gyeongbuk Med Innovat Fdn K MEDI hub, New Drug Dev Ctr NDDC, Daegu 41061, South Korea; Kyonggi Univ, Coll Convergence & Integrated Sci, Dept Chem, Suwon 16227, South Korea; Kyungpook Natl Univ, Dept Biol Educ, Daegu 41566, South Korea; Korea Univ, Dept Life Sci, Seoul 02841, South Korea; Korea Adv Inst Sci & Technol KAIST, Dept Biol Sci, Daejeon 34141, South Korea; Kyung Hee Univ, Kyung Hee Univ Hosp, Coll Med, Dept Pathol, Seoul 02447, South Korea; Kyung Hee Univ, Kyung Hee Univ Hosp, Coll Med, Dept Neurol, Seoul 02447, South Korea; Ajou Univ, Inst Med Sci, Sch Med, Suwon 16499, South Korea; Yonsei Univ, Coll Life Sci & Biotechnol, Dept Syst Biol, Seoul 03722, South Korea; Univ Oklahoma, Coll Med, Dept Surg, Oklahoma City, OK 73104 USA; Dong A Univ, Coll Med, Dept Anat & Cell Biol, Busan 49201, South Korea | ; Song, Ji-Joon/C-1721-2011; Woo, Jae-Sung/J-4531-2017; Kim, So-Woon/GQR-1282-2022; Kim, Min-Sik/KFS-9148-2024 | 55929681900; 57552826900; 57221527784; 7102963490; 57212308322; 57200994073; 59358914800; 23469151400; 57203598905; 59510334400; 7404786865; 57061327700; 57215648932; 56542578700; 7402834733; 54417697400; 55318967100; 57192905667; 55335086500; 35292205600 | jehyun-yoon@ouhsc.edu;mkim@dgist.ac.kr;jjung@khu.ac.kr;jnyjjy@dau.ac.kr; | NEUROTHERAPEUTICS | NEUROTHERAPEUTICS | 1933-7213 | 1878-7479 | 21 | 6 | SCIE | CLINICAL NEUROLOGY;NEUROSCIENCES;PHARMACOLOGY & PHARMACY | 2024 | 6.9 | 6.7 | 0.67 | 2025-05-07 | 1 | 1 | Schwann cells; Hippo/MST pathway; RNA-binding protein; let-7b; p38 alpha/MAPK14 | NEGATIVE REGULATOR; PROTEIN; PHOSPHORYLATION; BIOGENESIS; MICRORNAS; PROMOTES; COMPLEX; BINDING; MICROPROCESSOR; PROLIFERATION | Hippo/MST pathway; let-7b; p38α/MAPK14; RNA-binding protein; Schwann cells | Animals; Cells, Cultured; Hippo Signaling Pathway; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Nerve Degeneration; Peripheral Nervous System Diseases; Protein Serine-Threonine Kinases; Schwann Cells; Signal Transduction; baculoviral IAP repeat containing protein 2; baculoviral IAP repeat containing protein 3; benzenesulfonamide derivative; bmp8b protein; bone morphogenetic protein receptor 2; cyclin D1; dishevelled 1; frmd6 protein; fzd8 protein; Ki 67 antigen; large tumor suppressor protein; lysosome associated membrane protein 1; mammalian ste20 like kinase 1; messenger RNA; microRNA; microRNA let 7b; mitogen activated protein kinase 14; myelin; myelin basic protein; neuroprotective agent; neurotrophin receptor p75; nucleolin; peptides and proteins; protein c jun; protein serine threonine kinase; protein serine threonine kinase inhibitor; quaking protein; RNA binding protein; serine threonine protein kinase 3; Smad4 protein; Smad7 protein; unclassified drug; Wnt5a protein; wwc1 protein; xmu mp 1; YAP signaling protein; microRNA; protein serine threonine kinase; adult; animal experiment; animal model; animal tissue; Article; binding affinity; bioinformatics; cell dedifferentiation; cell proliferation; cheminformatics; controlled study; demyelination; drug efficacy; drug mechanism; drug protein binding; drug targeting; ex vivo study; gene expression regulation; gene silencing; hippo signaling; in vitro study; in vivo study; male; mouse; mRNA expression level; neuropathology; neuroprotection; nonhuman; peripheral nerve; peripheral neuropathy; polypharmacology; protein phosphorylation; protein transport; Schwann cell; Wallerian degeneration; animal; C57BL mouse; cell culture; drug effect; drug therapy; genetics; metabolism; nerve degeneration; peripheral neuropathy; physiology; signal transduction | English | 2024 | 2024-10 | 10.1016/j.neurot.2024.e00458 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Conception rate according to the size and location of corpus luteum and coexistent follicle before embryo transfer in Hanwoo | The size and location of the corpus luteum and the presence of coexistent follicles are crucial factors in synchronizing recipients and determining the suitability for embryo transfer. However, there has been a recent decline in conception rates after embryo transfer, which is attributed to environmental pollution, uterine inflammation, ovarian cysts, and other factors. Therefore, we conducted experiments to establish a novel criterion for successful embryo transfer assessment. To assess the suitability for embryo transfer one day before transfer, we conducted ultrasound examinations equipped with a vaginal probe to evaluate the corpus luteum and coexistent follicle. We found that instances with corpus luteum and coexistent follicles (diameter: > 10 mm) constituted the majority (69.7%) of cases. When comparing the fertility rates of cases in which the corpus luteum and coexistent follicle (diameter: > 10 mm) were located on the same ovary and cases in which they were not, higher fertility rates were observed when the corpus luteum and coexistent follicle (diameter: > 10 mm) were on different ovaries. Our study revealed a high incidence of corpus luteum and coexistent follicles with a diameter exceeding 10 mm. Therefore, our findings suggest that the co-occurrence of the corpus luteum and a large follicle can serve as a new standard for the evaluation of embryo transfer suitability. | Lim, Su-Geun; Yi, Junkoo; Ha, Jaejung; Park, Jinyeon; Kwon, Woo-Sung; Yu, Daejung; Ryoo, Zaeyoung; Kim, Daehyun | Kyungpook Natl Univ, Inst Life Sci & Biotechnol, Sch Life Sci, Daegu 41566, South Korea; Hankyong Natl Univ, Sch Anim Life Convergence Sci, Ansung 17579, South Korea; Gyeongsangbuk Do Livestock Res Inst, Yeongju 36052, South Korea; Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, South Korea; Livestock Inst, Chonnam Agr Res & Extens Serv, Gangjin 59213, South Korea; Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat Biores Grp, Daegu 41566, South Korea; Chonnam Natl Univ, Dept Anim Sci, Gwangju 61186, South Korea | ; Kwon, Woo-Sung/J-4391-2014; Yi, Junkoo/JBR-8507-2023; Kwon, Woo-Sung/J-6731-2019 | 56044587400; 56182537200; 55848402300; 58762853300; 54383715800; 58762647300; 16937104900; 57211228843 | jaewoong64@knu.ac.kr;kimdhbio@jnu.ac.kr; | JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY | J ANIM SCI TECHNOL | 2672-0191 | 2055-0391 | 66 | 6 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE;VETERINARY SCIENCES | 2024 | 3.2 | 6.8 | 0 | 2025-05-07 | 0 | 0 | Corpus luteum; Coexistent follicle; Embryo transfer; Conception rate; Hanwoo | PREGNANCY; PROGESTERONE; PROGRAMS | Coexistent follicle; Conception rate; Corpus luteum; Embryo transfer; Hanwoo | English | 2024 | 2024 | 10.5187/jast.2024.e31 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Editorial Material | Decreased CD19⁺CD24hⁱCD38hⁱ Regulatory B Cells in Alopecia Areata | Lee, Jong Yeong; Lim, Hyo Jung; Kim, sang-Hyun; Lee, Geon-Jong; Nam, Kyung-Hwa; Park, Jin; Choi, jin Kyeong | Jeonbuk Natl Univ, Med Sch, Dept Immunol, Jeonju, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, Dept Pharmacol, Daegu, South Korea; Jeonbuk Natl Univ, Med Sch, Dept Dermatol, Jeonju, South Korea; Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Res Inst Clin Med, Biomed Res Inst, Jeonju, South Korea | ; Kim, Sang-Hyun/KQU-4555-2024 | 58556824300; 58556904700; 57210450420; 58352722500; 7203003225; 35076360600; 50261279600 | airmd@jbnu.ac.kr;jkchoi@jbnu.ac.kr; | JOURNAL OF INVESTIGATIVE DERMATOLOGY | J INVEST DERMATOL | 0022-202X | 1523-1747 | 144 | 9 | SCIE | DERMATOLOGY | 2024 | 5.7 | 6.8 | 0.53 | 2025-05-07 | 2 | 2 | Alopecia areata; Autoimmune disease; IL-10; Regulatory B cells; STAT Transcription Factors | ADP-ribosyl Cyclase 1; Adult; Alopecia Areata; Antigens, CD19; B-Lymphocytes, Regulatory; CD24 Antigen; Female; Humans; Male; Membrane Glycoproteins; Middle Aged; ADP ribosyl cyclase/cyclic ADP ribose hydrolase 1; CD19 antigen; CD24 antigen; gamma interferon; interleukin 10; ADP ribosyl cyclase/cyclic ADP ribose hydrolase 1; CD19 antigen; CD24 antigen; CD38 protein, human; membrane protein; alopecia areata; Article; CD8+ T lymphocyte; flow cytometry; frequency; hair follicle; human; pre B lymphocyte; regulatory B lymphocyte; adult; female; immunology; male; metabolism; middle aged | English | 2024 | 2024-09 | 10.1016/j.jid.2024.02.004 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | Article | Effects of supplemental bacteriophage on the gut microbiota and nutrient digestibility of ileal-cannulated pigs | This study measured the potential changes of the microbiota in the gastrointestinal tract and energy and nutrient digestibility by supplemental bacteriophages in pigs. Twelve castrated male pigs (initial mean body weight = 29.5 +/- 2.3 kg) were surgically cannulated using T-cannula. The animals were housed individually in pens equipped with a feeder and a nipple waterer. The pigs were allotted to 1 of 3 experimental diets in a quadruplicated 3 x 2 Latin square design with 3 experimental diets, 2 periods, and 12 pigs resulting in 8 replicates per diet. The 3 diets were a control mainly based on corn and soybean meal with no antibiotics or bacteriophages, a diet containing 0.1% antibiotics, and a diet containing 0.2% bacteriophages. On day 5 of the experimental period, feces were collected and on days 6 and 7, ileal digesta were collected. Genomic DNA for bacteria were extracted from the ileal digesta and feces and the V4 region of the 16S rRNA gene was amplified. The ileal and fecal digestibility of energy, dry matter, organic matter, crude protein, and fiber was unaffected by dietary antibiotics or bacteriophages. At the phylum level, the supplemental antibiotic or bacteriophage tended to result in a higher proportion of Firmicutes ( p = 0.059) and a lower proportion of Bacteroidetes ( p = 0.099) in the ileal digesta samples compared with the control group with no difference between the antibiotic and bacteriophage groups. At the genus level, the supplemental antibiotic or bacteriophage tended to result in a higher proportion of Lactobaci l us ( p = 0.062) and a lower proportion of Bacteroides ( p = 0.074) and Streptococcus ( p = 0.088) in the ileal digesta compared with the control group with no difference between the antibiotic and bacteriophage groups. In the feces, supplemental antibiotics or bacteriophages reduced the proportion of Bifidobacterium compared with the control group ( p = 0.029) with no difference between the antibiotic and bacteriophage groups. Overall, supplemental antibiotics and bacteriophages showed positive effect on the microbiota of in the ileal digesta without largely affecting energy or nutrient digestibility, with no differences between the antibiotic and bacteriophage groups in growing pigs. | Jo, Hyunwoong; Han, Geongoo; Kim, Eun Bae; Kong, Changsu; Kim, Beob Gyun | Konkuk Univ, Monogastnc Anim Feed Res Inst, Seoul 05029, South Korea; Brown Univ, Mol Microbiol & Immunol, Providence, RI 02912 USA; Kangwon Natl Univ, Dept Appl Anim Sci, Chunchon 24341, South Korea; Kyungpook Natl Univ, Dept Anim Sci, Sangju 37224, South Korea; Konkuk Univ, Dept Anim Sci & Technol, Seoul 05029, South Korea | Kim, Beob/B-5634-2009 | bgkim@konkuk.ac.kr; | JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY | J ANIM SCI TECHNOL | 2672-0191 | 2055-0391 | 66 | 2 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE;VETERINARY SCIENCES | 2024 | 3.2 | 6.8 | 8 | Additive; Antibiotic; Digestibility; Probiotic; Pig; Lactobacillus | GROWTH-PERFORMANCE; DIETARY SUPPLEMENTATION; FEED ANTIBIOTICS; WEANLING PIGS; PROBIOTICS; AVILAMYCIN; SYMBIOSIS; MICROFLORA; ADDITIVES; RESPONSES | English | 2024 | 2024 | 10.5187/jast.2023.e96 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Evaluation of zinc oxide and copper oxide nanoparticles as potential alternatives to antibiotics for managing fowl typhoid in broilers | Antimicrobial resistance poses challenges to humans and animals, especially to the poultry sector in control of fowl typhoid with antibiotics, leading to increased mortality and food insecurity. Therefore, it is essential to develop more effective medications as alternatives to antibiotics. Currently, zinc oxide and copper oxide nanoparticles are of such significant interest due to their antibacterial properties. This study aimed to evaluate antimicrobial activity of zinc oxide and copper oxide nanoparticles against fowl typhoid in broilers. Ninety broiler chicks were raised under suitable management conditions. On day 10 of age, chicks were divided into six groups: control negative, control positive, T-1, T-2, T-3, and T-4. On day 19 of age, chicks in all groups except control negative were infected with Salmonella gallinarum (0.2 mL, 10(8) CFU/mL). After appearance of clinical signs, the treatments (Florfenicol; 50 mg/L drinking water [T-1], and zinc oxide + copper oxide nanoparticles; 25 + 10 mg/kg/d [T-2], 37.5 + 15 mg/kg/d [T-3], and 50 + 20 mg/kg/d [T-4]) were administered to chicks. Chicks were sacrificed on 26th and 30th day of age, and samples of blood and tissue were obtained. Hematological analysis with gross and histopathological examination of spleen, thymus and bursa of Fabricius was performed. Results revealed that there was no visible congestion in spleen and thymus of T-3 and T-4 at 11th day post infection. Antibody level against new castle's disease and lymphoproliferative response showed no significant difference in all groups. However, phagocytic response in nanoparticles treated groups exhibited a notable (p < 0.01) distinction compared to control positive. Notably, T-3 demonstrated the highest level of phagocytic activity. Hematological parameters, including lymphocytes, heterophils, eosinophils, and heterophils/lymphocytes ratio in groups T-2, T-3, and T-4, indicated significant (p < 0.01) difference compared to control positive. However, lymphocytes, heterophils, and heterophils/lymphocytes ratio in groups T-2, T-3, and T-4 showed no significant difference when compared to T-1. Nanoparticle treated groups showed decreased (p < 0.01) congestion of spleen and thymus as compared to control positive. Overall, zinc oxide and copper oxide nanoparticles have potential to serve as an alternative to florfenicol in treatment of fowl typhoid. | Raza, Muhammad Atif; Kim, Eungyung; Shakeel, Muhammad; Fiaz, Muhammad; Ma, Lei; Kim, Hyeonjin; Kim, Chae Yeon; Liu, Zhibin; Huang, Ke; Park, Kanghyun; Javed, Muhammad Tariq; Kim, Myoung Ok | Kyungpook Natl Univ, Res Ctr Horse Ind, Dept Anim Sci & Biotechnol, Sangju 37224, South Korea; Pir Mehr Ali Shah Arid Agr Univ, Fac Vet & Anim Sci, Rawalpindi 44000, Pakistan; Univ Agr Faisalabad, Fac Vet Sci, Dept Pathol, Faisalabad 38000, Pakistan | ; Shakeel, Muhammad/GLV-4501-2022; Javed, Muhammad/A-3808-2013 | 58291484800; 57217871658; 57209179360; 59378992500; 57217867673; 57343180400; 57966906800; 58640210100; 58639636600; 58530860300; 7006578045; 8934745900 | ok4325@knu.ac.kr; | JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY | J ANIM SCI TECHNOL | 2672-0191 | 2055-0391 | 66 | 5 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE;VETERINARY SCIENCES | 2024 | 3.2 | 6.8 | 2.27 | 2025-04-16 | 3 | 3 | Antimicrobial resistance; Salmonella gallinarum; Infection; Poultry health; Immunology | SALMONELLA-GALLINARUM INFECTION; HEMATOLOGICAL PARAMETERS; PATHOLOGICAL-CHANGES; GROWTH-PERFORMANCE; CUO NANOPARTICLES; POULTRY; SUPPLEMENTATION; RESISTANCE; CHICKEN; NANOTECHNOLOGY | Antimicrobial resistance; Immunology; Infection; Poultry health; Salmonella gallinarum | English | 2024 | 2024 | 10.5187/jast.2023.e91 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Generation of induced pluripotent stem cells from the Asian bats | Preservation of native Korean bats is crucial for maintaining ecological balance, as they play a vital role in insect control, pollination, and seed dispersal within their ecosystems. The present study details the establishment of bat induced pluripotent stem cells (BatiPSCs) from two Asian and Korean bats (Hypsugo alaschanicus and Pipistrellus abramus) using the Sendai Reprogramming Kit. Colonies of BatiPSCs, exhibiting distinctive features, were manually selected and expanded following successful transfection. Characterization of BatiPSCs revealed the expression of pluripotency markers, such as Octamer-binding transcription factor 4 (Oct4), SRY (sex-determining region Y)-box 2 and Nanog, with notably increased Oct4 levels and reduced Myc proto-oncogene expression compared with those noted in other induced pluripotent stem cell sources. BatiPSCs displayed positive staining for alkaline phosphatase and demonstrated the ability to form embryoid bodies, while also inducing teratomas in non-immune nude mice. Additionally, green fluorescent protein (GFP)-expressing BatiPSCs were generated and used for chimeric mouse production, with slight GFP signals detected in the neck region of the resulting mouse foetuses. These findings demonstrate the successful generation and characterization of BatiPSCs, emphasizing their potential applications in chimeric animal models, and the protection of endangered bat species. | Lee, Younsu; Koo, Okjae; Saadeldin, Islam M. | RedGene Inc, Div R&D, Seoul, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu, South Korea; nSAGE Inc, Incheon 21999, South Korea; King Faisal Specialist Hosp & Res Ctr, Comparat Med Dept, Riyadh, Saudi Arabia; Res Ctr, Riyadh, Saudi Arabia | Saadeldin, Islam/J-6729-2013; Saadeldin, Islam M./J-6729-2013 | 58196320800; 57197017299; 37862173300 | okjae.koo@n-sage.com;imohamed@kfshrc.edu.sa; | INTERNATIONAL JOURNAL OF VETERINARY SCIENCE AND MEDICINE | INT J VET SCI MED | 2314-4580 | 2314-4599 | 12 | 1 | ESCI | VETERINARY SCIENCES | 2024 | 3.2 | 6.8 | 0 | 2025-05-07 | 2 | 2 | Native bats; induced pluripotent stem cells; reprogramming; chimera | IN-VIVO; DIFFERENTIATION; DERIVATION | chimera; induced pluripotent stem cells; Native bats; reprogramming | alkaline phosphatase; amino acid; green fluorescent protein; messenger RNA; Myc protein; octamer transcription factor 4; transcription factor NANOG; transcription factor Sox2; animal cell; animal experiment; animal tissue; Article; Asia; bat; blastocyst; chimera; controlled study; cytoplasm; embryo; embryoid body; endoderm; extracellular matrix; female; fetus; fibroblast cell line; genetic transfection; Hypsugo alaschanicus; immunofluorescence assay; induced pluripotent stem cell; Korea; male; Masson staining; mouse; mRNA expression level; nonhuman; nuclear reprogramming; periodic acid Schiff stain; Pipistrellus; Pipistrellus abramus; real time polymerase chain reaction; stem cell culture; teratoma | English | 2024 | 2024-12-31 | 10.1080/23144599.2024.2384835 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Growth performance and nitrogen excretion of broiler chickens fed low protein diets supplemented with crystalline amino acids | This study was conducted to determine the effects of amino acid (AA) supplementation in low-protein (LP) diets on growth performance and nitrogen (N) excretion. A total of 175 7 -dayold Ross 308 male broilers, with a mean body weight (BW) of 165 g (standard deviation = 11.2 g), were grouped into five blocks by BW and allocated to seven treatments according to a randomized complete block design with five replicate cages at five birds per cage. Dietary treatments comprised a control diet containing 20.0% crude protein (CP) and six LP diets containing either 18.5% or 17.0% CP. These LP diets were supplemented with either no AA supplementation, indispensable AA, or both indispensable and dispensable AA (glutamic acid and glycine). Birds were fed experimental grower diets from day 7 to 21 and then commercial finisher diets until day 28. During the grower period (day 7 to 21), birds fed LP diets supplemented with indispensable AA exhibited greater (p < 0.05) BW, body weight gain (BWG), feed intake (FI), and gain-to-feed ratio (G:F) than birds fed LP diets without crystalline AA and were comparable to birds fed the control diet. During the finisher period (day 21 to 28), birds fed LP diets supplemented with indispensable AA showed greater (p < 0.05) BW than birds fed LP diets without crystalline AA, and their growth performance was comparable to birds fed the control diet. Throughout the overall period, supplementing indispensable AA in LP diets resulted in elevated (p < 0.05) BWG, FI, and G:F more than those of LP diets without crystalline AA and were comparable to those of the control diet. Supplementing indispensable AA in LP diets decreased amount and coefficient of N excretion as much as the control diet. Dispensable AA supplementation in LP diets did not influence growth performance and N excretion. In conclusion, supplementing indispensable AA in LP diets maintains growth performance and N excretion until the dietary CP lowers from 20.0% to 17.0% during the grower period. As long as dietary CP is above 17.0%, dispensable AA may not be deficient in LP diets during the grower period. | Cho, Inho; An, Su Hyun; Yoon, June Hyeok; Namgung, Nyun; Kong, Changsu | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, South Korea; Kyungpook Natl Univ, Res Inst Innovat Anim Sci, Sangju 37224, South Korea; Easy Holdings Co Ltd, Livestock Sci R&D Ctr, Seoul 06253, South Korea; Kyungpook Natl Univ, Dept Anim Sci, Sangju 37224, South Korea | 안, 수현/JFK-5079-2023 | 58509432600; 57216974969; 57995779900; 36195934000; 36027521600 | changsukong@knu.ac.kr; | JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY | J ANIM SCI TECHNOL | 2672-0191 | 2055-0391 | 66 | 1 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE;VETERINARY SCIENCES | 2024 | 3.2 | 6.8 | 0.76 | 2025-04-16 | 0 | 1 | Amino acid; Broiler; Growth performance; Low protein diet; Nitrogen excretion | BODY-COMPOSITION; GLUTAMIC-ACID; GLYCINE; QUALITY; LEVEL; FEED; MEAL | Amino acid; Broiler; Growth performance; Low protein diet; Nitrogen excretion | English | 2024 | 2024 | 10.5187/jast.2023.e131 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Lauric acid reduces apoptosis by inhibiting FOXO3a-signaling in deoxynivalenol-treated IPEC-J2 cells | Deoxynivalenol (DON) is the most common mycotoxin contaminant of food or feed worldwide and causes disease in animals. Lauric acid (LA) is a medium-chain fatty acid useful for barrier functions such as antimicrobial activity in the intestine of monogastric animals. However, the molecular mechanisms by which lauric acid exerts its effects on the deoxynivalenolexposed small intestine have not been studied. We used an intestinal porcine epithelial cell line (IPEC-J2) as an in vitro model to explore the molecular mechanism of lauric acid in alleviating deoxynivalenol-induced damage. We found that lauric acid reversed deoxynivalenol-induced reduction in cell viability. Our quantitative real-time polymerase chain reaction results indicated that lauric acid alleviated deoxynivalenol-induced apoptosis through Annexin-V. Additionally, immunofluorescence and Western blotting showed that lauric acid attenuated deoxynivalenol-induced forkhead box O3 (FOXO3a) translocation into the nucleus. These results suggest that lauric acid attenuates forkhead box O3 translocation in the small intestine damaged by deoxynivalenol, thereby reducing apoptosis. In conclusion, this study found that lauric acid alleviates deoxynivalenol-induced damage in intestinal porcine epithelial cell line through various molecular mechanisms. | Kim, Na Yeon; Lee, Sang In | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, South Korea; Kyungpook Natl Univ, Res Inst Innovat Anim Sci, Sangju 37224, South Korea | silee78@knu.ac.kr; | JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY | J ANIM SCI TECHNOL | 2672-0191 | 2055-0391 | 66 | 5 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE;VETERINARY SCIENCES | 2024 | 3.2 | 6.8 | 0 | Intestinal porcine epithelial cell line (IPEC-J2 cells); Deoxynivalenol; Lauric acid; Apoptosis; Foxo3a | CASPASE-ACTIVATED DNASE; PROLIFERATION; TOXICITY; DEFENSE | English | 2024 | 2024 | 10.5187/jast.2023.e92 | 바로가기 | 바로가기 | 바로가기 |
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