연구성과로 돌아가기
2024 연구성과 (34 / 286)
※ 컨트롤 + 클릭으로 열별 다중 정렬 가능합니다.
Excel 다운로드
| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ○ | Article | Evaluating the potential of chemically modified bamboo for sustainable and green construction | The purpose of the paper is to investigate the effectiveness of using acid-based chemical treatment to the durability, physiochemical, structural, and thermal properties that characterize bamboo as a sustainable building material. The study explicitly compares the effectiveness of acetic acid and zinc chloride as chemical modifiers with reference samples. The findings indicate that the chemical treatment of acetic acid yields optimized results by reducing water absorption to 9 % and swelling to 56 %, 21 %, and 12 % in terms of length, width, and thickness respectively. Furthermore, the flexure, tensile, and shear strengths of the acetic acid treated samples show significant improvement by 22 %–53 %, 9 %–35 %, and 36 %–42 % respectively for varying sections of bamboo, while the compressive strength compromises by 11 % except for the top section where it enhances by 41 %. Zinc chloride treated samples show improved mechanical strengths as well. To determine the mechanism behind these improvements, the effect of esterification on the carbonyl/hydroxyl absorbance ratio is analyzed using FTIR, which shows an increase in cellulose crystallinity as determined by XRD. Thermal degradation is also analyzed by TG/DSC tests, revealing the decrease in weight loss and exothermic thermal flow. However, the study finds limited effectiveness of zinc chloride as a chemical treatment on bamboo due to the dissolution of lignin by free zinc ions. These findings resonate globally, holding significant implications for eco-friendly construction. They highlight the potential of acid-based chemical treatment to improve bamboo as a sustainable building material, aligning with worldwide sustainability goals as SDGs 9, 13, and 11. © 2024 | Tariq, Maryam; Khushnood, Rao Arsalan; Babar, Zaeem Bin; Basit, Muhammad Abdul | Institute of Environmental Sciences and Engineering (IESE), School of Civil and Environmental Engineering (SCEE), National University of Sciences and Technology (NUST), Sector H-12, Islamabad, 44000, Pakistan; Department of Structural, Geotechnical and Building Engineering, Politecnico di Torino, Corso Duca degli Abruzzi 24, Turin, 10129, Italy, Tunneling Institute of Pakistan, Garden Ave Shakar Parian, Islamabad, 44000, Pakistan; Institute of Energy and Environmental Engineering, University of the Punjab, Lahore, 54590, Pakistan, Department of Environmental, Materials Science and Engineering, Kyungpook National University (KNU) - Daegu Campus, South Korea; Institute of Environmental Sciences and Engineering (IESE), School of Civil and Environmental Engineering (SCEE), National University of Sciences and Technology (NUST), Sector H-12, Islamabad, 44000, Pakistan | 58900382000; 56386027800; 56106569100; 57210068754 | rao.khushnood@polito.it; | Journal of Building Engineering | J BUILD ENG | N/A | 2352-7102 | 86 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENGINEERING, CIVIL | 2024 | 7.4 | 5.2 | 2.28 | 2025-05-07 | 6 | Acetic acid; Bamboo; Chemical treatment; Physio-chemical properties; Sustainable construction material | Bamboo; Chlorine Compounds; Compression Strength; Crystallinity; Degradation; Ph; Bamboo; Chlorine compounds; Compressive strength; Crystallinity; Degradation; Intelligent buildings; pH; Sustainable development; Swelling; Water absorption; Zinc chloride; Acid yields; Chemical modifiers; Chemical treatments; Chemically modified; Green constructions; Physio-chemical; Physio-chemical properties; Sustainable building materials; Sustainable construction; Sustainable construction material; Acetic acid | English | Final | 2024 | 10.1016/j.jobe.2024.108634 | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | Generic Quantum Blockchain-Envisioned Security Framework for IoT Environment: Architecture, Security Benefits and Future Research | Quantum cryptography has the potential to secure the infrastructures that are vulnerable to various attacks, like classical attacks, including quantum-related attacks. Therefore, quantum cryptography seems to be a promising technology for the future secure online infrastructures and applications, like blockchain-based frameworks. In this article, we propose a generic quantum blockchain-envisioned security framework for an Internet of Things (IoT) environment. We then discuss some potential applications of the proposed framework. We also highlight the security advantages of quantum cryptography-based systems. We explain the working of blockchain, applications of blockchain, types of blockchain, the structure of blockchain, the structure of blockchain in a classical blockchain, and the structure of a block in a quantum blockchain context. Next, the adverse effects of quantum computing on the security of blockchain-based frameworks are highlighted. Furthermore, the comparisons of quantum cryptography-based security schemes, like quantum key distribution, quantum digital signature, and quantum hashing schemes, are provided. Finally, some future research directions related to the designed generic quantum blockchain-envisioned security framework for IoT are provided. | Wazid, Mohammad; Das, Ashok Kumar; Park, Youngho | Graph Era Deemed Univ, Dept Comp Sci & Engn, Dehra Dun, India; Int Inst Informat Technol, Ctr Secur Theory & Algorithm Res, Hyderabad, India; Old Dominion Univ, Virginia Modeling Anal & Simulat Ctr, Suffolk, VA 23435 USA; Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea | wazid, mohammad/X-4211-2018; Das, Ashok Kumar/U-2790-2019; WAZID, MOHAMMAD/X-4211-2018 | 55480987400; 55450732800; 56962990300 | wazidkec2005@gmail.com;iitkgp.akdas@gmail.com;parkyh@knu.ac.kr; | IEEE OPEN JOURNAL OF THE COMPUTER SOCIETY | IEEE OPEN J COMP SOC | 2644-1268 | 5 | ESCI | COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;COMPUTER SCIENCE, THEORY & METHODS;ENGINEERING, ELECTRICAL & ELECTRONIC;COMPUTER SCIENCE, INFORMATION SYSTEMS | 2024 | 8.2 | 5.2 | 3.19 | 2025-04-16 | 5 | 10 | Blockchains; Security; Quantum computing; Quantum cryptography; Internet of Things; Quantum mechanics; Quantum key distribution; quantum blockchain; quantum key distribution; quantum digital signature; quantum hashing; security | BIG DATA ANALYTICS; KEY DISTRIBUTION; ENABLED INTERNET; SCHEME; SIGNATURE; CRYPTOGRAPHY; PROTOCOL | Internet of Things; quantum blockchain; Quantum cryptography; quantum digital signature; quantum hashing; quantum key distribution; security | Authentication; Blockchain; Internet of things; Quantum computers; Quantum theory; Block-chain; Environment architectures; Quantum blockchain; Quantum Computing; Quantum digital signatures; Quantum hashing; Security; Security frameworks; Quantum cryptography | English | 2024 | 2024 | 10.1109/ojcs.2024.3397307 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Mapping top-two-floor corner coordinates to building strains in deep latent space | Structural health monitoring is vital for ensuring building safety but faces numerous challenges, such as sensor durability, maintenance costs, and data loss. To address these issues, this study introduces a deep learning framework designed to obviate the need for ongoing maintenance of strain gauges. The framework aims to map the top-two-floor corner coordinates of a building to its strains in deep latent space. The framework comprises four steps: grouping coordinates, standardizing coordinates, generating a coordinate map, and learning the deep latent space. Here, learning the deep latent space refers to compressing high-dimensional input space features into low-dimensional deep latent space features to address the mapping problem while reducing overfitting and improving the explainability of a deep neural network for practical engineering applications. Once the deep latent space is learned, building strains can be predicted by observing only the top part of the building, eliminating the need for continuous maintenance of strain gauges in structural health monitoring. The proposed framework is evaluated on a four-story scaled building and demonstrates exceptional mapping performance in the learned deep latent space. | Park, Jun Su; Jang, Seung Kyu; Hong, Taehoon; Lee, Dong-Eun; Park, Hyo Seon | Yonsei Univ, Dept Architecture & Architectural Engn, Seoul 03722, South Korea; Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, Daegu, South Korea | ; Park, Jun Su/HTR-3899-2023 | 57161433100; 58766582900; 57969349700; 56605563300; 55669886900 | hspark@yonsei.ac.kr; | JOURNAL OF BUILDING ENGINEERING | J BUILD ENG | 2352-7102 | 82 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENGINEERING, CIVIL | 2024 | 7.4 | 5.2 | 0 | 2025-05-07 | 0 | 0 | Structural health monitoring; Strain prediction; Deep learning; Deep latent space; Computer vision | SYSTEM-IDENTIFICATION; MONITORING-SYSTEM; MODEL | Computer vision; Deep latent space; Deep learning; Strain prediction; Structural health monitoring | Buildings; Deep neural networks; Floors; Maintenance; Mapping; Strain; Strain gages; Structural health monitoring; Building safety; Coordinate maps; Data loss; Deep latent space; Deep learning; High-dimensional; Learning frameworks; Maintenance cost; Strain prediction; Strain-gages; Computer vision | English | 2024 | 2024-04-01 | 10.1016/j.jobe.2023.108279 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Mimicking chronic alcohol effects through a controlled and sustained ethanol release device | Alcohol consumption, a pervasive societal issue, poses considerable health risks and socioeconomic consequences. Alcohol-induced hepatic disorders, such as fatty liver disease, alcoholic hepatitis, chronic hepatitis, liver fibrosis, and cirrhosis, underscore the need for comprehensive research. Existing challenges in mimicking chronic alcohol exposure in cellular systems, attributed to ethanol evaporation, necessitate innovative approaches. In this study, we developed a simple, reusable, and controllable device for examining the physiological reactions of hepatocytes to long-term alcohol exposure. Our approach involved a novel device designed to continuously release ethanol into the culture medium, maintaining a consistent ethanol concentration over several days. We evaluated device performance by examining gene expression patterns and cytokine secretion alterations during long-term exposure to ethanol. These patterns were correlated with those observed in patients with alcoholic hepatitis. Our results suggest that our ethanol-releasing device can be used as a valuable tool to study the mechanisms of chronic alcohol-mediated hepatic diseases at the cellular level. Our device offers a practical solution for studying chronic alcohol exposure, providing a reliable platform for cellular research. This innovative tool holds promise for advancing our understanding of the molecular processes involved in chronic alcohol-mediated hepatic diseases. Future research avenues should explore broader applications and potential implications for predicting and treating alcohol-related illnesses. | Kim, Wanil; Chu, Jin-Ok; Kim, Do-Yeon; Lee, Soo-Hyeon; Choi, Chang-Hyung; Lee, Kyung-Ha | Gyeongsang Natl Univ, Sch Med, Dept Biochem, Jinju 52727, South Korea; Gyeongsang Natl Univ, Inst Med Sci, Sch Med, Jinju 52727, South Korea; Daegu Haany Univ, Dept Cosmet Sci & Technol, Gyongsan 38610, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Pharmacol, Daegu 41940, South Korea; Pusan Natl Univ, Dept Mol Biol, Busan 46241, South Korea; Yeungnam Univ, Sch Chem Engn, Gyongsan 38541, South Korea; Pusan Natl Univ, Inst Syst Biol, Busan 46241, South Korea | Kim, Do-Yeon/AET-3021-2022; Choi, Chang-Hyung/M-7053-2017 | 7405813437; 57409175800; 57203012542; 57219300478; 22949722800; 54967786000 | chchoi@yu.ac.kr;khlee@pusan.ac.kr; | JOURNAL OF BIOLOGICAL ENGINEERING | J BIOL ENG | 1754-1611 | 18 | 1 | SCIE | BIOCHEMICAL RESEARCH METHODS;BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2024 | 6.5 | 5.2 | 0 | 2025-05-07 | 0 | 0 | Ethanol; Ethanol-releasing device; Polydimethylsiloxane; Alcohol | LIVER-DISEASE; CC-CHEMOKINE; IN-VITRO; RECEPTOR; ANGIOGENESIS; PATHOGENESIS; ACTIVATION; EXPRESSION; CYTOKINES; BURDEN | Alcohol; Ethanol; Ethanol-releasing device; Polydimethylsiloxane | alanine aminotransferase; alcohol; aspartate aminotransferase; dimeticone; alcoholic hepatitis; alcoholism; Article; concentration (parameter); controlled study; correlational study; cytokine release; enzyme blood level; gene expression; Hep-G2 cell line; human; human cell; liver toxicity; long term exposure | English | 2024 | 2024-05-07 | 10.1186/s13036-024-00428-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | National variability in soil organic carbon stock predictions: Impact of bulk density pedotransfer functions | Accurate soil organic carbon storage (SOCS) estimation is crucial for sustaining ecosystem health and mitigating climate change impacts. This study investigated the accuracy and variability of SOCS predictions, focusing on the role of pedotransfer functions (PTFs) in estimating soil bulk density (BD). Utilizing a comprehensive dataset from the Korean Rural Development Administration (RDA database), which includes 516 soil horizons, we evaluated 36 widely-used BD PTFs, well-established formulas that estimate BD by considering soil properties, including soil organic carbon (SOC), soil organic matter (OM), sand, gravel, silt, and clay. These PTFs demonstrated varying levels of precision, with root mean squared errors (RMSE) ranging from 0.177 to 0.377 Mg m(-3) and coefficients of determination (R-2) from 0.176 to 0.658; hence, the PTFs have been classified into excellent, moderate, and poor-performing groups for predicting BD. Further, a novel PTF based on an exponential function of SOC was developed, showing superior predictive power (R-2 = 0.73) compared to existing PTFs, using an independent validation dataset. Our findings reveal significant differences in SOCS predictions and observations among the PTFs, with a p-value <0.05. The highest concentrations of SOCS were noted in forest soils, considerably above the national average, highlighting the importance of tailored soil management practices to enhance carbon sequestration. These findings are crucial for refining PTF precision to improve the accuracy of national SOCS estimates, supporting effective land management and climate change mitigation strategies. (c) 2024 International Research and Training Center on Erosion and Sedimentation, China Water and Power Press, and China Institute of Water Resources and Hydropower Research. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | Do, May-Thi Tuyet; Van, Linh Nguyen; Le, Xuan-Hien; Nguyen, Giang, V; Yeon, Minho; Lee, Giha | Kyungpook Natl Univ, Dept Adv Sci & Technol Convergence, 2559 Gyeongsangdaero, Sangju Si 37224, South Korea; Kyungpook Natl Univ, Disaster Prevent Emergency Management Inst, 2559 Gyeongsang Daero, Sangu Si 37224, South Korea; Thuyloi Univ, 175 Tay Son, Hanoi 10000, Vietnam | Nguyen, Giang/GQZ-4595-2022; Le, Xuan-Hien/AAZ-9166-2021 | 58059176800; 57297359100; 57209735659; 57297771000; 57223436971; 35069799400 | tuyetmay@knu.ac.kr;linhnguyen@knu.ac.kr;hienlx@knu.ac.kr;alsgh2620@knu.ac.kr;leegiha@knu.ac.kr; | INTERNATIONAL SOIL AND WATER CONSERVATION RESEARCH | INT SOIL WATER CONSE | 2095-6339 | 2589-059X | 12 | 4 | SCIE | ENVIRONMENTAL SCIENCES;SOIL SCIENCE;WATER RESOURCES | 2024 | 7.3 | 5.2 | 0 | 2025-05-07 | 1 | 1 | RDA database; Soil organic carbon stock prediction; Pedotransfer function; Bayesian model average; Regression method | IGNITION LOSS; FOREST SOILS; NITROGEN; TOPSOIL; MATTER | Bayesian model average; Pedotransfer function; RDA database; Regression method; Soil organic carbon stock prediction | English | 2024 | 2024-12 | 10.1016/j.iswcr.2024.04.002 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | PERSON-CENTERED PRACTICE OF NURSES IN LONG-TERM CARE HOSPITALS | Kim, Su Hyun; Choi, Yoon Saeng | Kyungpook Natl Univ, Daegu, South Korea | INNOVATION IN AGING | INNOV AGING | 2399-5300 | 8 | SCIE;SSCI | GERIATRICS & GERONTOLOGY;GERONTOLOGY | 2024 | 4.3 | 5.2 | 0 | English | 2024 | 2024-12-31 | 10.1093/geroni/igae098.3462 | 바로가기 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Article | Research Note: Comparative evaluation of pathogenicity in SPF chicken between different subgroups of H5N6 high pathogenicity avian influenza viruses | Since 2014, periodic outbreaks of high pathogenicity avian influenza (HPAI) caused by clade 2.3.4.4 H5 HPAI virus (HPAIV) have resulted in huge economic losses in the Korean poultry industry. During the winter season of 2016-2017, clade 2.3.4.4e H5N6 HPAIVs classified into 5 subgroups (C1-5) were introduced into South Korea. Interestingly, it was revealed that the subgroup C2 and C4 viruses were predominantly distributed throughout the country, whereas detection of the subgroup C3 viruses was confined in a specific local region. In the present study, we conducted comparative evaluation of the pathogenicity of viruses belonging to subgroups C2 and C3 (H15 and HN1 strains) in specific pathogen-free (SPF) chickens, and further compared them with previously determined pathogenicity of subgroup C4 (ES2 strain) virus. The HN1 strain showed lower viral replication in tissues, less transmissibility, and higher mean chicken lethal dose than the H15 and ES2 strains in SPF chickens. Considering that the HN1 strain has a different NS gene segment from the H15 and ES2 strains, the reassortment of the NS gene segment likely affects their infectivity and transmissibility in chickens. These findings emphasize the importance of monitoring the genetic characteristics and pathogenic features of HPAIVs to effectively control their outbreaks in the field. | Baek, Yoon-Gi; Lee, Yu-Na; Cha, Ra Mi; Park, Min-Ji; Lee, Youn-Jeong; Park, Choi-Kyu; Lee, Eun-Kyoung | Anim & Plant Quarantine Agcy, Avian Influenza Res & Diagnost Div, Gimcheon Si 39660, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Vet Biomed Sci, Daegu 41566, South Korea | 57211667015; 59858247700; 57194199657; 57202785813; 55533095600; 24768064900; 25938359000 | parkck@knu.ac.kr;ensenble@korea.kr; | POULTRY SCIENCE | POULTRY SCI | 0032-5791 | 1525-3171 | 103 | 2 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | 2024 | 4.2 | 5.2 | 0.92 | 2025-05-07 | 1 | 1 | high pathogenicity avian influenza virus; pathogenicity; South Korea | VIRULENCE; EVOLUTION | H5N6; high pathogenicity avian influenza virus; pathogenicity; South Korea | Animals; Chickens; Disease Outbreaks; Influenza A Virus, H5N6 Subtype; Influenza in Birds; Phylogeny; Virulence; animal; avian influenza; epidemic; Gallus gallus; phylogeny; veterinary medicine; virulence | English | 2024 | 2024-02 | 10.1016/j.psj.2023.103289 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Research Note: Muscle hypertrophy is associated with reversed sexual dimorphism in body size of quail | Sexual dimorphism is phenotypic differences between males and females in the same species. In general, males in most animals are larger than females at the same age, however, in quail, females have a larger body size with greater muscle mass than males. To understand what characteristics in muscle growth play roles in reversed sexual dimorphism in quail, the weights and the characteristics of the pectoralis major and gastrocnemius muscles (PM and GM, respectively) of male and female quail were compared in the current study. The data showed that 15-wk old female quail have significantly heavier bodies, and PM and GM weights compared to male quail (1.27-folds, 1.29 folds, and 1.16-folds, respectively). To compare muscle characteristics such as hypertrophy (increased size) and hyperplasia (increased cell number), the PM and GM were stained using hematoxylin and eosin, and then histological characteristics such as total cross-sectional area (CSA), number and size of myofibers, and muscle bundle of the muscles were measured and analyzed. In both PM and GM, there were no differences in total numbers of myofibers and muscle bundles as well as the average numbers of myofibers per bundle between sexes. However, the sizes of myofiber and the bundle were significantly increased in female compared to male (1.33-folds and 1.28-folds in PM, and both 1.23-folds in GM, respectively). The findings of the current study suggest that muscle hypertrophy in female quail, not hyperplasia, can be attributed to the sexual dimorphism in quail size. | Kim, Dong-Hwan; Lee, Joonbum; Lee, Boin; Lee, Kichoon | Ohio State Univ, Dept Anim Sci, Columbus, OH 43210 USA; Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, South Korea | Lee, Kichoon/G-2234-2012; Kim, Donghwan/LRC-0840-2024 | 56621562800; 57194466213; 57218130871; 14123395400 | lee.2626@osu.edu; | POULTRY SCIENCE | POULTRY SCI | 0032-5791 | 1525-3171 | 103 | 1 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | 2024 | 4.2 | 5.2 | 2.04 | 2025-04-16 | 2 | 2 | sexual dimorphism; hypertrophy; myofiber; muscle bundle; quail | hypertrophy; muscle bundle; myofiber; quail; sexual dimorphism | Animals; Body Size; Chickens; Female; Hypertrophy; Male; Pectoralis Muscles; Quail; Sex Characteristics; animal; body size; female; Gallus gallus; hypertrophy; male; pectoral muscle; quail; sexual characteristics; veterinary medicine | English | 2024 | 2024-01 | 10.1016/j.psj.2023.103263 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Rule-based automation algorithm for generating 2D deliverables from BIM | Efficient generation of two-dimensional (2D) deliverables from building information models (BIM) entails remarkable challenges, impacting project productivity. To address this issue, BIMDrawGEN, a rule-based algorithm, was developed in this study to streamline the creation of essential 2D deliverables during the design development phase. This approach involves an analysis of the BIM design process, resulting in the derivation of 76 automation rule sets for generating logically defined 2D deliverables from BIM data. A prototype add-in interfacing with BIM authoring tools was developed to validate the model, demonstrating significant reductions in work nodes and time by 94.54 % and 93.26 %, respectively, for BIM-based drawing creation. Significant reduction in working hours, from nearly a week to under half a day, using BIMDrawGEN enhances both industrial and academic outcomes. This efficiency enables designers to focus more on design rather than documentation. This study identifies and addresses inefficient processes in BIM, demonstrating that targeted automation could significantly improve design quality and productivity. | Kim, Yije; Chin, Sangyoon; Choo, Seungyeon | Sungkyunkwan Univ, Dept Convergence Engn Future City, Suwon 16419, South Korea; Sungkyunkwan Univ, Sch Civil Architectural Engn & Landscape Architect, Suwon 16419, South Korea; Kyungpook Natl Univ, Sch Architecture, Daegu 41566, South Korea | ; Choo, Seungyeon/JFB-0390-2023 | 57357791000; 7202600955; 36835366900 | dlwpek@skku.edu;schin@skku.edu;choo@knu.ac.kr; | JOURNAL OF BUILDING ENGINEERING | J BUILD ENG | 2352-7102 | 97 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENGINEERING, CIVIL | 2024 | 7.4 | 5.2 | 0.38 | 2025-05-07 | 2 | 3 | Building information modeling (BIM); Design development stage; BIM design; BIM-Based drawing; 2D deliverable; 2D extract; Automation; Rule-based algorithm | 2D deliverable; 2D extract; Automation; BIM design; BIM-Based drawing; Building information modeling (BIM); Design development stage; Rule-based algorithm | Building information modeling; Building information modeling design; Building information modeling-based drawing; Building Information Modelling; Design development; Design development stage; Development stages; Model-based OPC; Modeling designs; Rule based algorithms; Two-dimensional; Two-dimensional deliverable; Two-dimensional extract; Building Information Model | English | 2024 | 2024-11-15 | 10.1016/j.jobe.2024.111033 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Shaking table tests and numerical simulations on RC frames retrofitted with friction-damped brace | In this study, the dynamic response of double-story reinforced concrete (RC) space frames retrofitted with diagonally arranged friction damped-brace system was evaluated through shaking table tests. A simplified friction damper was proposed and tested under cyclic loading, later used to retrofit an RC frame. The splice of a conventional steel brace was converted into a friction damper, which requires limited technical expertise on site. Commercially available brake-pads were used as a friction material between the splice plates and bracing elements. An artificial ground motion characterized by a short period, similar to the Korean earthquake histories, was generated and used for the shaking table tests. The tested RC frame half-scaled of existing old structures in Korea. The shaking table tests results demonstrated that the dynamic response of the retrofitted RC frame was improved with reduced drift demands. Additionally, a numerical modelling method for friction damped-brace system was developed, and the dynamic responses of retrofitted RC frame with the proposed friction damper was numerically investigated using OpenSees. The numerical simulation results agreed well with the experimental observations. | Woo, Jonghun; Haroon, Muhammad; Lee, Junseop; Shin, Kyungjae; Lee, Heedu | Kyungpook Natl Univ, Dept Architectural Civil Environm & Energy Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Reg Ctr Land Infrastruct & Transport Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Architecture, Daegu 41566, South Korea | ; Haroon, Muhammad/E-6370-2018 | 57210344487; 57211005074; 57221623386; 14039501000; 53865180300 | lhdza@knu.ac.kr; | JOURNAL OF BUILDING ENGINEERING | J BUILD ENG | 2352-7102 | 82 | SCIE | CONSTRUCTION & BUILDING TECHNOLOGY;ENGINEERING, CIVIL | 2024 | 7.4 | 5.2 | 1.14 | 2025-05-07 | 7 | 7 | friction damped-brace; shaking table tests; retrofitting; openseas model | SEISMIC PROTECTION; PRECAST STRUCTURES; CABLE SYSTEM; DESIGN; STEEL | Friction damped-brace; OpenSees model; Retrofitting; Shaking table tests | Dynamic response; Earthquakes; Numerical methods; Numerical models; Reinforced concrete; Retrofitting; Seismic response; Conventional steel; Friction damped-brace; Friction damper; Opensee model; Opensees; Reinforced concrete frames; Shaking table tests; Space frames; Steel braces; Technical expertise; Friction | English | 2024 | 2024-04-01 | 10.1016/j.jobe.2023.108277 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Meeting Abstract | SUPPORTIVE CARE NEEDS AND INTERVENTIONS IN PANCREATIC CANCER PATIENTS AND THEIR CAREGIVERS: A SCOPING REVIEW | Fu, Liang; Kim, Su Hyun; Hayward, Matt; Vieira, Candice; Parikh, Alexander; Song, Lixin | Univ Texas Hlth Sci Ctr San Antonio, San Antonio, TX USA; Kyungpook Natl Univ, Daegu, South Korea | Hayward, Matt/F-3569-2010; Song, Lixin/GXZ-9894-2022 | INNOVATION IN AGING | INNOV AGING | 2399-5300 | 8 | SCIE;SSCI | GERIATRICS & GERONTOLOGY;GERONTOLOGY | 2024 | 4.3 | 5.2 | 0 | English | 2024 | 2024-12-31 | 10.1093/geroni/igae098.4324 | 바로가기 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Article | Treatment Outcomes of Olfactory Neuroblastoma: A Multicenter Study by the Korean Sinonasal Tumor and Skull Base Surgery Study Group | Objectives. Due to the rarity of olfactory neuroblastoma (ONB), there is ongoing debate about optimal treatment strategies, especially for early-stage or locally advanced cases. Therefore, our study aimed to explore experiences from multiple centers to identify factors that influence the oncological outcomes of ONB. Methods. We retrospectively analyzed 195 ONB patients treated at nine tertiary hospitals in South Korea between December 1992 and December 2019. Kaplan-Meier survival analysis was used to evaluate oncological outcomes, and a Cox proportional hazards regression model was employed to analyze prognostic factors for survival outcomes. Furthermore, we conducted 1:1 nearest-neighbor matching to investigate differences in clinical outcomes according to the use of neoadjuvant chemotherapy. Results. In our cohort, the 5-year overall survival (OS) rate was 78.6%, and the 5-year disease-free survival (DFS) rate was 62.4%. The Cox proportional hazards model revealed that the modified Kadish (mKadish) stage and Dulguerov T status were significantly associated with DFS, while the mKadish stage and Hyams grade were identified as prognostic factors for OS. The subgroup analyses indicated a trend toward improved 5-year DFS with dural resection in mKadish A and B cases, even though the result was statistically insignificant. Induction chemotherapy did not provide a survival benefit in this study after matching for the mKadish stage and nodal status. Conclusion. Clinical staging and pathologic grading are important prognostic factors in ONB. Dural resection in mKadish A and B did not show a significant survival benefit. Similarly, induction chemotherapy also did not show a survival benefit, even after stage matching. | Hong, Sang Duk; Park, Song, I; Kim, Ji Heui; Heo, Sung Jae; Cho, Sung-Woo; Won, Tae-Bin; Cho, Hyun-Jin; Lee, Dong Hoon; Mun, Sue Jean; Park, Soo Kyoung; Kim, Yong-Wan; Kim, Dong-Young | Sungkyunkwan Univ, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Samsung Med Ctr, Seoul, South Korea; Inje Univ, Coll Med, Ilsan Paik Hosp, Dept Otolaryngol Head & Neck Surg, Goyang, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Seoul, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Daegu, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Otorhinolaryngol Head & Neck Surg, Coll Med, Seongnam, South Korea; Gyeongsang Natl Univ Hosp, Dept Otorhinolaryngol, Jinju, South Korea; Chonnam Natl Univ, Sch Med, Hwasun Hosp, Dept Otolaryngol Head & Neck Surg, Hwasun, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Otorhinolaryngol Head & Neck Surg, Yangsan, South Korea; Chungnam Natl Univ, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Daejeon, South Korea; Inje Univ, Haeundae Paik Hosp, Dept Otorhinolaryngol Head & Neck Surg, Busan, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Otorhinolaryngol Head & Neck Surg, 101 Daehak Ro, Seoul 03080, South Korea | ; 허, 성재/AAU-3921-2020; Hyun-Jin, Cho/K-1544-2019 | 24072844200; 57202418734; 27168153600; 55822906000; 57194716579; 21935553000; 57205203680; 55568531298; 56487096100; 57203275869; 57196171184; 56493287200 | dongkim@snu.ac.kr; | CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY | CLIN EXP OTORHINOLAR | 1976-8710 | 2005-0720 | 17 | 2 | SCIE | OTORHINOLARYNGOLOGY | 2024 | 3.4 | 5.2 | 1.04 | 2025-05-07 | 3 | 2 | Esthesioneuroblastoma; NeoadjuvantTherapy; Prognosis; Treatment Outcome | FOLLOW-UP; ESTHESIONEUROBLASTOMA; EXPERIENCE; CHEMOTHERAPY; RESECTION; SURVIVAL | Esthesioneuroblastoma; Neoadjuvant Therapy; Prognosis; Treatment Outcome | English | 2024 | 2024-05 | 10.21053/ceo.2023.00089 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Comparative metabolism of aschantin in human and animal hepatocytes | Aschantin, a tetrahydrofurofuran lignan with a 1,3-benzodioxole group derived from Flos Magnoliae, exhibits antioxidant, anti-inflammatory, cytotoxic, and antimicrobial activities. This study compared the metabolic profiles of aschantin in human, dog, mouse, and rat hepatocytes using liquid chromatography-high-resolution mass spectrometry. The hepatic extraction ratio of aschantin among the four species was 0.46-0.77, suggesting that it undergoes a moderate-to-extensive degree of hepatic metabolism. Hepatocyte incubation of aschantin produced 4 phase 1 metabolites, including aschantin catechol (M1), O-desmethylaschantin (M2 and M3), and hydroxyaschantin (M4), and 14 phase 2 metabolites, including O-methyl-M1 (M5 and M6) via catechol O-methyltransferase (COMT), six glucuronides of M1, M2, M3, M5, and M6, and six sulfates of M1, M2, M3, M5, and M6. Enzyme kinetic studies using aschantin revealed that the production of M1, a major metabolite, via O-demethylenation is catalyzed by cytochrome 2C8 (CYP2C8), CYP2C9, CYP2C19, CYP3A4, and CYP3A5 enzymes; the formation of M2 (O-desmethylaschantin) is catalyzed by CYP2C9 and CYP2C19; and the formation of M4 is catalyzed by CYP3A4 enzyme. Two glutathione (GSH) conjugates of M1 were identified after incubation of aschantin with human and animal liver microsomes in the presence of nicotinamide adenine dinucleotide phosphate and GSH, but they were not detected in the hepatocytes of all species. In conclusion, aschantin is extensively metabolized, producing 18 metabolites in human and animal hepatocytes catalyzed by CYP, COMT, UDP-glucuronosyltransferase, and sulfotransferase. These results can help in clarifying the involvement of metabolizing enzymes in the pharmacokinetics and drug interactions of aschantin and in elucidating GSH conjugation associated with the reactive intermediate formed from M1 (aschantin catechol). | Lee, Min Seo; Shim, Hyun Joo; Cho, Yong-Yeon; Lee, Joo Young; Kang, Han Chang; Song, Im-Sook; Lee, Hye Suk | Catholic Univ Korea, Coll Pharm, Bucheon 14662, South Korea; Catholic Univ Korea, BK21 Four Sponsored Adv Program SmartPharma Leader, Bucheon 14662, South Korea; Jeonbuk Natl Univ, Coll Pharm, Jeonju 54896, South Korea; Kyungpook Natl Univ, BK21 FOUR Community Based Intelligent Novel Drug D, Vessel Organ Interact Res Ctr VOICE, Res Inst Pharmaceut Sci,Coll Pharm, Daegu 41566, South Korea | Cho, Yong-Yeon/AAD-4263-2020; Kang, Han/I-5999-2019 | 57225079010; 57835859200; 55472207900; 57215684977; 36150873700; 7201564500; 35316111800 | sianalee@catholic.ac.kr; | ARCHIVES OF PHARMACAL RESEARCH | ARCH PHARM RES | 0253-6269 | 1976-3786 | 47 | 2 | SCIE | CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY | 2024 | 7.5 | 5.3 | 2.28 | 2025-05-07 | 5 | 8 | Aschantin; Metabolite identification; Cytochrome P450; 1,3-benzodioxole; GSH adduct | LIQUID-CHROMATOGRAPHY; FURFURAN LIGNANS; MAGNOLIAE-FLOS; HUMAN LIVER; PHARMACOKINETICS; CYTOCHROME-P450; MECHANISM; CONSTITUENTS | 1,3-benzodioxole; Aschantin; Cytochrome P450; GSH adduct; Metabolite identification | Animals; Benzodioxoles; Catechols; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dogs; Hepatocytes; Humans; Kinetics; Lignans; Mice; Microsomes, Liver; Rats; 1,3 benzodioxole derivative; aschantin; aschantin catechol; catechol methyltransferase; cytochrome P450 2C19; cytochrome P450 2C8; cytochrome P450 2C9; cytochrome P450 3A4; cytochrome P450 3A5; drug metabolite; glucuronide; glucuronosyltransferase; glutathione; hydroxyaschantin; lignan derivative; nicotinamide adenine dinucleotide phosphate; o desmethylaschantin; sulfate; sulfotransferase; unclassified drug; 1,3 benzodioxole derivative; aschantin; catechol derivative; cytochrome P450; cytochrome P450 2C19; cytochrome P450 2C9; cytochrome P450 3A; lignan; animal cell; Article; catalysis; controlled study; drug conjugation; drug metabolism; enzyme kinetics; hepatic extraction ratio; human; human cell; human versus animal comparison; liquid chromatography-mass spectrometry; liver cell; liver metabolism; liver microsome; mouse; nonhuman; rat; animal; dog; kinetics; liver cell; metabolism | English | 2024 | 2024-02 | 10.1007/s12272-023-01483-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Exploiting mechanoregulation via FAK/YAP to overcome platinum resistance in ovarian cancer | Cancer cells mechanically interact with the tumor microenvironment during cancer development. Mechanoreciprocity has emerged as a crucial factor affecting anti-cancer drug resistance during adjuvant therapy. Here, we investigated the focal adhesion kinase (FAK)/Yes-associated protein (YAP) signaling axis as a prospective strategy for circumventing cisplatin resistance in ovarian cancer (OC). The Cancer Genome Atlas (TCGA) data analysis revealed that FAK overexpression significantly correlated with unfavorable clinical outcomes in patients with ovarian cancer. AFM indentation experiments showed that cell elasticity depends on FAK activity. Notably, the combination of FAK inhibition and cisplatin treatment led to a 69 % reduction in the IC50 50 of cisplatin. This combined treatment also increased apoptosis compared to the individual treatments, along with the upregulation of the pro-apoptotic factor BAX and cleaved PARP. Suppressing FAK expression sequestered YAP in the cytosol, potentially reducing cellular proliferation and promoting apoptosis. Moreover, reduced FAK expression sensitized drug-resistant OC cells to cisplatin treatment owing to a decrease in nuclear tension, allowing the relocation of YAP to the cytosol. In a mouse model, the co-administration of an FAK inhibitor and cisplatin significantly suppressed tumor growth and increased apoptotic events and DNA fragmentation. . Our findings suggest that drug resistance can be attributed to the perturbation of mechanosensing signaling pathways, which drive the mechanical reinforcement of cancer cells. OC cells can restore their sensitivity to cisplatin treatment by strategically reducing YAP localization in the nucleus through FAK downregulation. | Dang, Loi Nguyen; Choi, Jinsol; Lee, Eunhee; Lim, Yeonju; Kwon, Jin-Won; Park, Soyeun | Keimyung Univ, Coll Pharm, Daegu 42601, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Pharm, BK21 FOUR Community Based Intelligent Novel Drug D, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu 41566, South Korea | 58564330400; 57667145200; 57444079000; 59299145900; 16202951700; 7501830233 | sypark20@kmu.ac.kr; | BIOMEDICINE & PHARMACOTHERAPY | BIOMED PHARMACOTHER | 0753-3322 | 1950-6007 | 179 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2024 | 7.5 | 5.3 | 0 | 2025-05-07 | 0 | 0 | AFM; Platinum resistance; Mechanotransduction; TCGA; Ovarian cancer; FAK/YAP | FOCAL ADHESION KINASE; FAK; CELLS; MECHANOTRANSDUCTION; YAP; CHEMOTHERAPY; ACTIVATION; MECHANISMS; CISPLATIN; MIGRATION | AFM; FAK/YAP; Mechanotransduction; Ovarian cancer; Platinum resistance; TCGA | Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Female; Focal Adhesion Kinase 1; Humans; Mechanotransduction, Cellular; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Signal Transduction; Transcription Factors; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; cisplatin; defactinib; DNA; focal adhesion kinase; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; protein Bax; YAP signaling protein; antineoplastic agent; cisplatin; focal adhesion kinase 1; PTK2 protein, human; signal transducing adaptor protein; transcription factor; YAP signaling protein; YAP1 protein, human; animal experiment; animal model; animal tissue; apoptosis; Article; cancer growth; cancer resistance; cancer tissue; cell proliferation; clinical outcome; controlled study; DNA fragmentation; down regulation; elasticity; enzyme activity; female; gene knockdown; human; human cell; IC50; mechanotransduction; mouse; mouse model; nonhuman; ovary cancer; pancreas cancer; protein localization; reinforcement (psychology); signal transduction; tension; animal; apoptosis; Bagg albino mouse; drug effect; drug resistance; drug screening; drug therapy; mechanotransduction; metabolism; nude mouse; ovary tumor; pathology; tumor cell line | English | 2024 | 2024-10 | 10.1016/j.biopha.2024.117335 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Higher integrability for weak solutions to parabolic multi-phase equations | In this paper, we establish a local higher integrability result for the gradient of a weak solution to a parabolic multi-phase equation. To achieve this, we prove parabolic Poincar & eacute; type inequalities and reverse H & ouml;lder type inequalities for the gradient of a weak solution in each of difference types of intrinsic cylinders. In particular, we formulate a delicate plan of alternatives and stopping time arguments to address the presence of two different transitions. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies. | Kim, Bogi; Oh, Jehan | Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea | 58904201600; 56673305300 | rlaqhrl4@knu.ac.kr;jehan.oh@knu.ac.kr; | JOURNAL OF DIFFERENTIAL EQUATIONS | J DIFFER EQUATIONS | 0022-0396 | 1090-2732 | 409 | SCIE | MATHEMATICS | 2024 | 2.3 | 5.3 | 1.52 | 2025-05-07 | 2 | 2 | Degenerate parabolic equations; Multi-phase problems; Weak solution; Higher integrability; Intrinsic cylinders | OMEGA-MINIMIZERS; REGULARITY; FUNCTIONALS; SYSTEMS | Degenerate parabolic equations; Higher integrability; Intrinsic cylinders; Multi-phase problems; Weak solution | English | 2024 | 2024-11-15 | 10.1016/j.jde.2024.07.012 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
페이지 이동: