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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Article | Red Ginseng Water Extract Aggravates Inflammation in Sebocytes and Outer Root Sheath Cells after Treatment with Lipopolysaccharide and Mice with Cutibacterium acnesinduced Inflammatory Nodules | Background: Ginseng, a well-known health-supportive herbal medicine in Korea, has various forms, including red ginseng (RG) produced through steaming and drying white ginseng. RG has been associated with numerous protective functions in various diseases. Objective: The objective of this study was to investigate whether RG water extract exacerbates inflammation in human sebocytes and outer root sheath (ORS) cells following treatment with lipopolysaccharide (LPS) and Cutibacterium acnes strain (ATCC 1182)-induced inflammatory nodules in mice. Methods: Sebocytes and ORS cells were isolated and cultured from the human scalp. Reverse transcription-polymerase chain reaction and enzyme-linked immunosorbent assay were used to measure the expression of inflammatory cytokine and sebum-related genes after treatment with RG and LPS. Mice with Cutibacterium acnesinduced inflammatory nodules were orally administered RG in water for two weeks, and immunofluorescence staining was performed to assess the inflammatory nodules. Results: RG enhanced LPS-mediated inflammation by increasing the mRNA and protein expression of interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor-α in sebocytes and ORS cells. RG also upregulated the expression of p-nuclear factor-kappa B (p-NFκB), p-c-Jun, and c-Jun N-terminal kinase (p-JNK) in LPS-treated sebocytes and ORS cells. Moreover, RG promoted LPS-induced sebum production in sebocytes. Additionally, RG hindered the improvement of inflammatory nodules in mice and increased the expression of inflammatory biomarkers, such as neutrophil, myeloperoxidase, and IL-1β, as well as tissue remodeling biomarkers, such as myeloperoxidase (MMP)-2, MMP-3, and MMP-9 in the inflammatory nodules. Conclusion: Our findings strongly suggest that RG exacerbates acne vulgaris. It is advisable to avoid using RG in patients with inflammatory acne. Copyright@2023 by The Korean Society for Medical Mycology. All right reserved. | Kwack, Mi Hee; Lee, Seung Soo; Lee, Weon Ju | Department of Immunology, School of Medicine, Kyungpook National University, Daegu, South Korea, BK21 FOUR KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea; Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea | 6507685557; 58509964900; 24474659000 | weonju@knu.ac.kr; | Journal of Mycology and Infection | 1226-4709 | 28 | 2 | 0 | 2025-06-25 | 0 | Cutibacterium acnes; Lipopolysaccharide; Outer root sheath cells; Red ginseng; Sebocytes | gelatinase A; gelatinase B; ginseng extract; immunoglobulin enhancer binding protein; interleukin 1beta; interleukin 6; interleukin 8; lipopolysaccharide; messenger RNA; myeloperoxidase; protein c jun; stress activated protein kinase; stromelysin; tumor necrosis factor; water; acne vulgaris; adult; animal experiment; animal model; animal tissue; Article; bacterial strain; cell culture; cell isolation; controlled study; dermatitis; enzyme linked immunosorbent assay; female; human; human cell; human tissue; immunofluorescence assay; in vitro study; in vivo study; mouse; mRNA expression level; neutrophil; nonhuman; outer root sheath cell; Propionibacterium acnes; protein expression level; protein phosphorylation; reverse transcription polymerase chain reaction; scalp; sebaceous cell; sebum; sebum secretion; skin cell; skin nodule; upregulation | English | Final | 2023 | 10.17966/jmi.2023.28.2.42 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | Article | Regenerative Injection Therapy on Tendon Healing: Dextrose Prolotherapy versus Platelet-Rich Plasma | The tendon is a dense connective tissue that connects muscle to bone and plays an essential role in joint motion. The injured tendon heals slowly ow-ing to its low cellularity and vascularity. This study aimed to evaluate and compare the effects of regenerative injection therapy (RIT), 20 % dextrose prolother-apy (DP), and platelet-rich plasma (PRP) injections that can promote tendon healing. Twenty-one New Zealand white rabbits were divided into the control, DP, and PRP treatment groups. The superficial digital flexor tendon (SDFT) of the right hindlimb of each rabbit was used. A round defect of 2 mm was induced. Approximately 0.2 mL of 20% dextrose and autologous PRP were injected into the proximal and distal ends of the SDFT mass. Radiographic and ultrasono-graphic examination and cross-sectional area (CSA) calculations were performed pre-operatively and at 2, 4, and 8 weeks. The SDFT of both limbs was transected for biomechanical and histomorphometric evaluations. The SDFT of the left limb was transected for intact control. Semi-quantitative analysis was performed to evaluate the histomorphometric properties. Additional analysis was performed using H&E, Masson’s trichrome, and immunohistochemical staining. The biomechanical evaluation showed that the treatment groups had higher tensile strength compared to the defect control group, while the PRP group had higher tensile strength than the DP group. On histological examination, the treatment groups appeared to be relatively closer to the remodeling phase of the healing process than the defect control group; the characteristics of the PRP group were closer to the remodeling phase than those of the DP group. The ultrasonograph-ic examination showed different tendencies. Increased values in the CSA were observed during the early period in the treatment groups. This study suggests that PRP and DP can promote the healing of tendon injury, and these effects were superior with PRP than that with DP. © The Korean Society of Veterinary Clinics. | Lim, Jungmin; Lee, Won-Jae; Seo, Min-Soo; Jeong, Seong Mok; Ku, Sae-Kwang; Kwon, Youngsam; Yun, Sungho | Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu, 41566, South Korea; Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu, 41566, South Korea; Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu, 41566, South Korea; Department of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon, 34134, South Korea; Department of Anatomy and Histology, College of Korean Medicine, Daegu Haany University, Gyeongsan, 38610, South Korea; Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu, 41566, South Korea; Department of Anatomy and Histology, College of Korean Medicine, Daegu Haany University, Gyeongsan, 38610, South Korea | 58549936200; 57205486455; 35254332100; 7402425314; 7006331005; 7403459426; 57201366734 | shyun@knu.ac.kr; | Journal of Veterinary Clinics | 1598-298X | 40 | 2 | 0 | 2025-06-25 | 0 | dextrose prolotherapy; platelet-rich plasma; superficial digital flexor tendon; tendon healing | English | Final | 2023 | 10.17555/jvc.2023.40.2.93 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Conference paper | Regulation and therapeutic applications of autophagy in cancer | Autophagy is a cell death mechanism that involves the destruction of substances within an organism's cells in response to several external stresses. A double-membrane structure of autophagosomes transports degradable components, including damaged organelles and misfolded proteins, to lysosomes for breakdown and recycling. With the development of technology, there is accumulating evidence that autophagy is associated with a variety of human disorders, including cancer. During the progression from benign to malignant cancer, autophagy suppresses cancer cells while boosting the growth and spread of cancerous tumor cells. In conclusion, the exploitation of autophagy as a prospective target for the treatment of cancer is becoming an increasingly popular avenue for researchers. This study has reviewed the regulatory processes of autophagy in cancer, the double role of autophagy in cancer, and the therapeutic applications of autophagy in cancer based on the underlying mechanisms of autophagy in cancer for pancreatic cancer, breast cancer, and how existing drugs can inhibit tumor progression. © 2023 SPIE. | Yingting, Jiang | The College of Natural Sciences, Kyungpook National University, Daegu, 610058, South Korea | 58624004400 | 13980610156@163.com; | Proceedings of SPIE - The International Society for Optical Engineering | 0277-786X | 12789 | 0 | 2025-06-25 | 0 | autophagy; breast cancer; drug resistance; inhibitors; pancreatic cancer | Cancer cells; Diseases; Photonics; Tumors; Autophagosome; Autophagy; Breast Cancer; Drug-resistance; External stress; Human disorders; Inhibitor; Misfolded proteins; Pancreatic cancers; Therapeutic Application; Cell death | English | Final | 2023 | 10.1117/12.2692769 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Book chapter | Regulatory impact analysis: The experience of policy analysis in the Korean central government | [No abstract available] | Kim, Song June; Ha, Sun Gwon | Kyungpook National University, South Korea, Korea Society for Regulatory Studies, South Korea; Biotechnology Policy Research Center, Korea Research Institute of Bioscience and Biotechnology, South Korea | 57218679608; 58165252700 | Policy Analysis in South Korea | 0 | 2025-06-25 | 0 | English | Final | 2023 | 10.1332/policypress/9781447362579.003.0005 | 바로가기 | 바로가기 | |||||||||||||||||||||
| ○ | Article | Relative Risks for Dementia among Individuals with Glaucoma: A Meta-Analysis of Observational Cohort Studies | Purpose: To investigate the relative risks (RRs) for dementia among individuals with glaucoma. Methods: We conducted a search of PubMed, Web of Science, Scopus, and Cochrane databases for observational cohort studies examining the association between glaucoma and dementia until March 2023. Two authors independently screened all titles and abstracts according to predefined inclusion and exclusion criteria. Pooled RR and 95% confidence intervals (CIs) were generated using random-effect models. Results: The meta-analysis included 18 cohort studies conducted in eight countries and involving 4,975,325 individuals. The pooled RR for the association between glaucoma and all-cause dementia was 1.314 (95% CI, 1.099–1.572; I2 = 95%). The pooled RRs for the associations of open-angle glaucoma with Alzheimer dementia and Parkinson disease were 1.287 (95% CI, 1.007–1.646; I2 = 96%) and 1.233 (95% CI, 0.677–2.243; I2 = 73%), respectively. The pooled RRs for the associations of angle-closure glaucoma with all-cause dementia and Alzheimer dementia were 0.978 (95% CI, 0.750–1.277; I2 = 17%) and 0.838 (95% CI, 0.421–1.669; I2 = 16%), respectively. No evidence of publication bias was detected in the Begg-Mazumdar adjusted rank correlation test (p = 0.47). Conclusions: Based on current observational cohort studies, there is evidence supporting that glaucoma is a risk factor for dementia in the adult population. © 2023 The Korean Ophthalmological Society. | Huh, Min Gu; Kim, Young Kook; Lee, Jaekyoung; Shin, Young In; Lee, Yun Jeong; Choe, Sooyeon; Kim, Dai Woo; Jeong, Yoon; Jeoung, Jin Wook; Park, Ki Ho | Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea, Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea, Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea, EyeLight Data Science Laboratory, Seoul National University College of Medicine, Seoul, South Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea, Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea, Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea, Department of Ophthalmology, Chungnam National University Hospital, Daejeon, South Korea; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea, Department of Ophthalmology, Chungnam National University Hospital, Daejeon, South Korea; Department of Ophthalmology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, South Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea, Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea, Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea, Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea | 58291747400; 55908959500; 57210579891; 57219467882; 57215833281; 57211978439; 57095192800; 57221403812; 9640226000; 56276582800 | eyedry@snu.ac.kr; | Korean Journal of Ophthalmology | 1011-8942 | 37 | 6 | 0.98 | 2025-06-25 | 3 | Alzheimer disease; Dementia; Glaucoma; Meta-analysis; Open-angle glaucoma | English | Final | 2023 | 10.3341/kjo.2023.0059 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Article | Removal Area of Deteriorated Concretes for Concrete Repairs | This work proposes the concrete removal area for the repairs of deteriorated concretes based on comparison between three types of concrete deterioration (water staining, cracks, delamination) and chloride content testing results. Since concrete deteriorates due to the chloride in deicing salts according to the mechanism of concrete deterioration, chloride content tests were conducted on pier cap, pier, and abutment. The values of the chloride content measured on water stained concrete surface were significantly higher than those on non-water stained concrete surface, which supposedly were led by deicing salts. The values of chloride content surrounding the steel reinforcements of deteriorated concrete elements such as cracks and delaminations were well above the critical value of 1.2 kg/m3. Comparing proposed removal areas in this study, which are ① water stain boundary+50 mm, ②delamination initiation+150 mm, and ③ crack end+150 mm, large sound areas are expected to be removed in the case of water stain boundary+50 mm. On the other hand, the advantages of delamination initiation+150 mm and crack end+150 mm are that they minimize the loss of sound areas when compared with cases of water staining. Consequently, the proposal of removal area is: “The removal area of the deteriorated concrete is the maximum value between delamination initiation+150 mm and crack end+150 mm”. © 2023 by Korea Concrete Institute. | Jeong, Yoseok; Lee, Ilkeun; Min, Geunhyeong; Kim, Kihwan; Kim, Wooseok | Department of Construction and Disaster Prevention Engineering, Kyungpook National University, Sangju, 37224, South Korea; Expressway & Transportation Research Institute, Construction & Environment Research Group, Hwaseong, 20896, South Korea; Department of Civil Engineering, Chungnam National University, Daejeon, 34134, South Korea; Department of Construction and Disaster Prevention Engineering, Kyungpook National University, Sangju, 37224, South Korea; Department of Civil Engineering, Chungnam National University, Daejeon, 34134, South Korea | 54980727300; 55455771300; 57211278402; 58142365300; 56286036900 | wooseok@cnu.ac.kr; | Journal of the Korea Concrete Institute | 1229-5515 | 35 | 1 | 0.12 | 2025-06-25 | 1 | chloride content; deterioration; maintenance; removal area; repairs | Korean | Final | 2023 | 10.4334/jkci.2023.35.1.059 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Review | Removal of heavy metals using Iris species: A potential approach for reclamation of heavy metal-polluted sites and environmental beautification | Globally, the number of heavy metal (HM)-polluted sites has increased rapidly in recent years, posing a serious threat to agricultural productivity, human health, and environmental safety. Hence, it is necessary to remediate HM-polluted sites to increase cultivatable lands for agricultural productivity, prevent hazardous effects to human health, and promote environmental safety. Removal of HMs using plants (phytoremediation) is a promising method as it is eco-friendly. Recently, ornamental plants have been widely used in phytoremediation programs as they can simultaneously eliminate HMs and are aesthetically pleasing. Among the ornamental plants, Iris species are frequently used; however, their role in HM remediation has not been reviewed yet. Here, the importance of Iris species in the ornamental industry and their different commercial aspects are briefly described. Additionally, the mechanisms of how the plant species absorb and transport the HMs to the above-ground tissues and tolerate HM stress are highlighted. The variation in HM remediation efficiency depending on the plant species, HM type and concentration, use of certain supplements, and experimental conditions are also discussed. Iris species are able to remove other hazards as well, such as pesticides, pharmaceutical compounds, and industrial wastes, from polluted soils or waste-water. Owing to the valuable information presented in this review, we expect more applications of the species in reclaiming polluted sites and beautifying the environment. | Naing, Aung Htay; Park, Da Young; Park, Hyeong Cheol; Kim, Chang Kil | Kyungpook Natl Univ, Dept Hort, Daegu 41566, South Korea; Natl Inst Ecol, Div Ecol Applicat Res, Ecol Technol Res Team, Seocheon 33657, South Korea | Naing, Aung Htay/AAF-4277-2019 | 37112768100; 57196010208; 35275668800; 7409880701 | hcpark@nie.re.kr;ckkim@knu.ac.kr; | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | ENVIRON SCI POLLUT R | 0944-1344 | 1614-7499 | 30 | 32 | SCIE | ENVIRONMENTAL SCIENCES | 2023 | N/A | 0.08 | 2025-06-25 | 3 | 2 | Environmental beautification; Heavy metals; Iris species; Phytoremediation efficiency; Phytoremediation strategy; Reclamation | CONTAMINATED SOILS; WASTE-WATER; EXOGENOUS GLUTATHIONE; CONSTRUCTED WETLAND; CADMIUM TOLERANCE; IRON PLAQUE; ACCUMULATION; PHYTOREMEDIATION; PLANTS; PSEUDACORUS | Environmental beautification; Heavy metals; Iris species; Phytoremediation efficiency; Phytoremediation strategy; Reclamation | Biodegradation, Environmental; Humans; Industrial Waste; Iris Plant; Metals, Heavy; Plants; Soil; Soil Pollutants; heavy metal; environmental quality; environmental risk; hazardous waste; heavy metal; land reclamation; phytoremediation; public health; soil pollution; soil remediation; bioremediation; human; industrial waste; Iris plant; plant; soil; soil pollutant | English | 2023 | 2023-07 | 10.1007/s11356-023-27732-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Research Article Monitoring of optimal conditions for producing fermented black soybeans rich in sulfur-containing amino acids | The optimal fermentation conditions for producing fermented black soybeans rich in sulfur-containing amino acids were investigated. Response surface methodology monitored fermentation conditions. A central composite design examined the effect of independent variables: enzyme concentration (X1) and fermentation time (X2) on yield and methionine content. Both factors significantly influenced these dependent variables. Enzyme concentration more profoundly affected amino nitrogen content than fermentation time. β-Glucan content and cystine level were primarily affected by fermentation time. We elicited each variable's regression formula and identified optimal fermentation conditions for functional compounds. The predicted optimum conditions were an enzyme concentration of 0.28-0.32% and a fermentation time of 58.0-62.0 min. Under these optimal conditions, each black soybean variety's sulfur amino acid content ranged from 818.62 to 922.62 mg/100 g, demonstrating significant variety differences. Copyright © 2023 The Korean Society of Food Preservation. | Yoon, Sung Ran; Lee, Jin Ju; Park, Jungmin; Ryu, Jung A.; Nam, Ju-Ock; Kang, Min Sook; Kim, Sun Hwa; Jeong, Yong Jin | Division of Agriculture Environment Research, Gyongsangbuk-do Agricultural Research and Extension Services, Daegu, 41404, South Korea; KMF Co., Ltd., Daegu, 41065, South Korea; Division of Agriculture Environment Research, Gyongsangbuk-do Agricultural Research and Extension Services, Daegu, 41404, South Korea; Division of Agriculture Environment Research, Gyongsangbuk-do Agricultural Research and Extension Services, Daegu, 41404, South Korea; School of Food Science and Technology, Kyungpook National University, Daegu, 41566, South Korea; Department of Agrofood Resources, National Academy of Agricultural Science, RDA, Wanju, 55365, South Korea; KMF Co., Ltd., Daegu, 41065, South Korea; KMF Co., Ltd., Daegu, 41065, South Korea, Department of Food Science and Technology, Keimyung University, Daegu, 42601, South Korea | 24400410500; 57210207134; 58859355400; 57216744726; 7201496105; 22634733100; 57200210310; 55558297500 | sryoon@korea.kr;yjjeong@kmu.ac.kr; | Korean Journal of Food Preservation | 1738-7248 | 30 | 6 | 0.14 | 2025-06-25 | 1 | black soybean; fermentation; response surface methodology; sulfur amino acid | English | Final | 2023 | 10.11002/kjfp.2023.30.6.905 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Article | Residue Monitoring and Dietary Risk Evaluation of Fungicide Propiconazole in Leafy Vegetables under Greenhouse Conditions | Residue monitoring of propiconazole (PCZ) in cabbage, shallot, and spinach was conducted under multi-trial greenhouse conditions. This study aimed to understand the fate of the applied fungicide in these vegetables. Furthermore, the associated health risk of PCZ in leafy vegetables was assessed through dietary risk assessment. Commercially available PCZ (22% suspension concentrate) was administered thrice according to the OECD fungicide application interval guideline. The plant samples were extracted using a slightly modified QuEChERS technique and analyzed using gas chromatography-tandem mass spectrometry. The average PCZ recovery was between 84.5% and 117.6%, with a <5% coefficient of variance. The dissipation of PCZ residue in cabbage, shallot, and spinach after 14 days was 96%, 90%, and 99%, respectively, with half-lives of <5 days. Meanwhile, dietary risk assessments of PCZ residues in the studied vegetables using the risk quotient (RQ) were significant < 100 (RQ < 100). Thus, the population groups considered in this study were not at substantial risk from consuming leafy vegetables sprayed with PCZ following critical, good agricultural practices. © 2023 The Korean Society of Environmental Agriculture. | Abdulkareem, Lawal; Oh, Ji-Eun; Kwak, Se-Yeon; Lee, Sang-Hyeob; Choi, Jae-Won; Sarker, Aniruddha; Kyung, Kee Sung; Kim, Tae Hwa; Kim, Jang-Eok | School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, South Korea; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, South Korea; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, South Korea; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, South Korea; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, South Korea; Department of Agro-Food Safety and Crop Protection, National Institute of Agricultural Sciences, Rural Development Administration, Wanju, 55365, South Korea; Department of Environmental and Biological Chemistry, College of Agriculture, Life and Environment Science, Chungbuk National University, Cheongju, 28644, South Korea; Analysis Technology and Tomorrow, Ltd, Daegu, 42703, South Korea; School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, South Korea | 58046579600; 58046469800; 57202752311; 57202747805; 59169559000; 57211874397; 7004203636; 57212609150; 7601387161 | jekim@knu.ac.kr; | Korean Journal of Environmental Agriculture | 1225-3537 | 42 | 3 | 0 | 2025-06-25 | 0 | Dietary risk assessment; Leafy vegetables; Maximum residue limits; Propiconazole; Residue monitoring | English | Final | 2023 | 10.5338/kjea.2023.42.3.23 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Book chapter | Response mechanism of plant stresses to secondary metabolites production | Secondary metabolites (SM) in plants are not only an essential source of natural compounds, but they also play an essential part in the plant's defense mechanism against infections and other environmental hazards. This is because SMs can encapsulate and transport natural compounds throughout the plant. The fields of medicine and cooking both make extensive use of plant-derived chemicals for a variety of reasons, including the production of pharmaceuticals and food additives. These substances have a wide range of applications in both of these fields. The formation and accumulation of SM can be influenced by a wide variety of factors, including but not limited to genetic, ontogenic, morphogenic, and environmental factors. Every one of the millions of secondary metabolites that plants create has the potential to perform a broad variety of tasks, including the ability to cause damage to eukaryotic organisms. Secondary metabolites are produced in large quantities by bacteria and other eukaryotic organisms, and these metabolites are consumed by the organisms themselves. Plants frequently utilize the apoplast or other specialized organelles such as the vacuole, in addition to a variety of self-tolerance mechanisms, to combat the poisons that they are exposed to. To produce these bioactive molecules successfully, it is necessary for the transport and self-tolerance mechanisms that are found in microbes and plants to collaborate closely with the biosynthetic enzymes that are involved. An extensive study has been conducted to identify and define the proteins that are responsible for transport and self-tolerance in a wide variety of viral illnesses. As a result of this discovery, several hypotheses concerning the physiological functions of various transporters have been developed. In addition to a summary of recent discoveries made in the fields of transport and self-tolerance research, this report features an up-to-date list of transporters that are categorized according to the substrates they move. If this information is utilized in the future, synthetic biology may one day be able to produce secondary metabolites that are of practical utility. © 2024 Elsevier Inc. All rights reserved. | Muhammad, Murad; Basit, Abdul; Wahab, Abdul; Li, Wen-Jun; Shah, Syed Tanveer; Mohamed, Heba I. | Phyto-Ecology Lab, Department of Botany, University of Peshawar, Khyber Pakhtunkhwa, Peshawar, Pakistan, Shanghai Centre for Plant Stress Biology, Centre of Excellence in Molecular Plant Science, Chinese Academy of Science, Shanghai, China; Department of Horticulture, Faculty of Crop Production Sciences, The University of Agriculture, Peshawar, Pakistan, Department of Horticultural Science, Kyungpook National University, Daegu, South Korea; State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, China; Shanghai Centre for Plant Stress Biology, Centre of Excellence in Molecular Plant Science, Chinese Academy of Science, Shanghai, China; Department of Horticulture, Faculty of Crop Production Sciences, The University of Agriculture, Peshawar, Pakistan; Department of Biological and Geological Sciences, Faculty of Education, Ain Shams University, Cairo, Egypt | 57223331609; 57218918852; 57225328914; 59882437000; 56089730700; 37102371200 | Fungal Secondary Metabolites: Synthesis and Applications in Agroecosystem | 6.81 | 2025-06-25 | 7 | Environmental challenges; Plant secondary metabolites; Response mechanism | English | Final | 2023 | 10.1016/b978-0-323-95241-5.00012-5 | 바로가기 | 바로가기 | ||||||||||||||||||||
| ○ | Article | Response of regulation of resistance genes, reactive oxygen species, and antioxidant enzymes to salicylic acid treatments in drought tolerant rice | Drought is one of the most important issues in crop production which may disrupt physiological processes and biochemical metabolism in rice plants, including the emergence of plant resistance gene expression such as OsAB13 and OsLEA, the formation of ROS (Reactive Oxygen Species), namely hydrogen peroxide (H2O2), as well as the emergence of gene expression related to antioxidant enzyme activity such as OsAPX1, OsCATA, Mn-SOD, Cu/Zn-SOD, and APX Cytosolic. Besides the emergence of plant resistance gene expression, ROS, and changes in gene expression related to antioxidant enzymes, rice plants also produce salicylic acid which acts as an endogenous signal to activate plant resistance gene responses and can encourage plant resistance responses such as antioxidant enzyme activity. The treatments in this study included: control, 15% PEG 6000, 15% PEG 6000 + SA 1 mM, and SA 1 mM. The results showed that the interaction between treatments and rice plant varieties significantly affected plant height, root length, total chlorophyll, and H2O2 content. The expression of the OsAPX1, OsCATA, Mn-SOD, and Cu/Zn-SOD genes increased in the 15% PEG 6000 treatment compared to the control. In the 15% PEG 6000 + SA 1 mM treatment, there was an increase in gene expression of APX Cytosolic, Cu/Zn-SOD, and OsCATA compared to the 15% PEG 6000 treatment. The OsLEA is expressed in Siakraya and Sertani 1 as an indicator of resistance to drought stress, and the OsAB13 is expressed in Indragiri, Sertani 1, and Siakraya varieties as an indicator of resistance to drought stress. © 2023, Eesti Pollumajandusulikool. All rights reserved. | Ubaidillah, M.; Oktaviani, F.; Mufadilah, M.A.; Avivi, S.; Thamrin, N.; Indrawati, A.; Puspito, A.N.; Kim, K.M.; Hartatik, S. | University of Jember, Faculty of Agriculture, Study Program of Agronomy, Jember Regency, East Java, 6812, Indonesia, University of Jember, Faculty of Agriculture, Study Program of Magister Biotechnology, Jember Regency, East Java, 6812, Indonesia; University of Jember, Faculty of Agriculture, Study Program of Magister Biotechnology, Jember Regency, East Java, 6812, Indonesia; University of Jember, Faculty of Agriculture, Study Program of Agronomy, Jember Regency, East Java, 6812, Indonesia; University of Jember, Faculty of Agriculture, Study Program of Agronomy, Jember Regency, East Java, 6812, Indonesia; University of Jember, Faculty of Agriculture, Study Program of Agronomy, Jember Regency, East Java, 6812, Indonesia; University of Jember, Faculty of Agriculture, Study Program of Agronomy, Jember Regency, East Java, 6812, Indonesia; University of Jember, Faculty of Agriculture, Study Program of Magister Biotechnology, Jember Regency, East Java, 6812, Indonesia; Division of Plant Biosciences, School of Applied BioSciences, College of Agriculture and Life Science, Kyungpook National University, Daegu, South Korea; University of Jember, Faculty of Agriculture, Study Program of Agronomy, Jember Regency, East Java, 6812, Indonesia | 56011434400; 58355315300; 58157593700; 57208834357; 58157762300; 58354002500; 55914230100; 34868260300; 58335263900 | srihartatik.faperta@unej.ac.id; | Agronomy Research | 1406-894X | 21 | Special Issue 1 | 0.7 | 2025-06-25 | 4 | and rice plants; antioxidant enzymes; drought stress; reactive oxygen species; resistance genes | English | Final | 2023 | 10.15159/ar.23.013 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Article | Response Prediction after Neoadjuvant Chemotherapy for Colon Cancer Using CT Tumor Regression Grade: A Preliminary Study | Purpose To investigate whether CT -based tumor regression grade (ctTRG) can be used to predict the response to neoadjuvant chemotherapy (NAC) in colon cancer. Materials and Methods A total of 53 patients were enrolled. Two radiologists independently assessed the ctTRG using the length, thickness, layer pattern, and luminal and extraluminal appearance of the tumor. Changes in tumor volume were also analyzed using the 3D Slicer software. We evaluated the association between pathologic TRG (pTRG) and ctTRG. Patients with R & ouml;del's TRG of 2, 3, or 4 were classified as responders. In terms of predicting responder and pathologic complete remission (pCR), receiver operating characteristic was compared between ctTRG and tumor volume change. Results There was a moderate correlation between ctTRG and pTRG (rho = -0.540, p < 0.001), and the interobserver agreement was substantial (weighted & kcy; = 0.672). In the prediction of responder, there was no significant difference between ctTRG and volumetry ( Az = 0.749, criterion: ctTRG <= 3 for ctTRG, Az = 0.794, criterion: <= -27.1% for volume, p = 0.53). Moreover, there was no significant difference between the two methods in predicting pCR ( p = 0.447). Conclusion might predict the response to NAC in colon cancer. The diagnostic performance of ctTRG was comparable to that of CT volumetry. | Je, Hwan Ju; Cho, Seung Hyun; Oh, Hyun Seok; Seo, An Na; Park, Byung Geon; Lee, So Mi; Kim, See Hyung; Kim, Gab Chul; Ryeom, Hunkyu; Choi, Gyu-Seog | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Radiol, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Kyungpook Natl Univ Hosp, Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Colorectal Canc Ctr, Daegu, South Korea; Kyungpook Natl Univ, Dept Radiol, Chilgok Hosp, 807 Hoguk Ro, Daegu 41404, South Korea | oh, hyunseok/V-5275-2017; Kim, Sang-Hyun/J-5402-2012 | 58714126300; 55686242700; 57216440602; 55804153700; 57211532915; 56824903400; 57216511386; 23004499400; 6505864513; 8058759100 | shcho2405@gmail.com; | JOURNAL OF THE KOREAN SOCIETY OF RADIOLOGY | 2951-0805 | 84 | 5 | 0.22 | 2025-06-25 | 1 | 1 | Colonic Neoplasm; Multidetector Computed Tomography; Neoadjuvant Therapy | RECTAL-CANCER; ADJUVANT CHEMOTHERAPY; STAGE-II; PREOPERATIVE CHEMORADIOTHERAPY; HISTOPATHOLOGICAL RESPONSE; CHEMORADIATION THERAPY; COLORECTAL-CANCER; SURVIVAL; OXALIPLATIN; FLUOROURACIL | Colonic Neoplasm; Multidetector Computed Tomography; Neoadjuvant Therapy | English | 2023 | 2023-09 | 10.3348/jksr.2022.0124 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | Article | Review of the Fabrication of SrFeO2.5 Thin Film and Its Functionalities | Brownmillerite transition metal oxides are materials with alternating layers of transition metal–oxygen octahedral (MO6) and transition metal–oxygen tetrahedral (MO4), which have attracted considerable attention because of their various physical properties, for example, ion conductors, catalysts, synaptic device properties, metal-insulator transition, and multiferroicity. In particular, we can easily control the structure of the SrFeO2.5 thin film through pulsed laser epitaxy conditions and heat treatment. In this paper, we will discuss the fabrication and properties of SrFeO2.5 thin films deposited using pulsed laser epitaxy. The developmental trend of SrFeO2.5 thin-film devices based on topotactic phase transition and the behavior of atoms will be examined to promote oxygen diffusion during the topotactic phase transition. Furthermore, the room-temperature ferroelectric and ferromagnetic phenomena utilizing the low-dimensional tetrahedral network within the brownmillerite structure will be discussed. © 2023 The Korean Physical Society. All rights reserved. | Kang, Kyeong Tae | Department of Physics, Kyungpook National University, Daegu, 41566, South Korea | 56002123900 | ktkang@knu.ac.kr; | New Physics: Sae Mulli | 0374-4914 | 73 | 3 | 0.12 | 2025-06-25 | 1 | Brownmillerite; Multiferroic; SrFeO2.5; Topotactic phase transition | Korean | Final | 2023 | 10.3938/npsm.73.210 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Review | Review of the Melting of West Antarctic Ice Shelves in the Amundsen Sea and Its Influence: Research Issues and Scientific Questions | The collapse of ice shelves is a process that can severely increase the rise of global sea-levels through the reduction of the buttressing effect of ice shelves and the consequent acceleration of the ice flow of ice sheets. In recent years, the West Antarctic ice shelves in the Amundsen Sea, whose buttressing effect is essential for a great part of the West Antarctic ice sheet, have been experiencing the most rapid melting and thinning in the world. The melting of the West Antarctic ice shelves is caused primarily by heat transported by Circumpolar Deep Water (CDW). For this reason, it is important to investigate ice-ocean interactions that could influence the melting of ice shelves and evaluate the stability of West Antarctic ice shelves. A lot of researchers have been actively investigating the West Antarctic ice shelves in the Amundsen Sea. High-impact journals have recognized the importance of and published studies on ice-ocean interactions occurring near and under the ice shelves as well as the connections among ice shelves. However, in situ observations are limited due to extreme weather and sea-ice conditions near the ice shelves; therefore, many scientific questions remain unanswered. This study introduces the characteristics of the Amundsen Sea and investigate the past and latest research issues in this region. This study also gives suggestions regarding important scientific questions and directions for future research that should help early-career scientists take the lead in future research on the melting dynamics of the West Antarctic ice shelves in the Amundsen Sea. © 2023 Ocean and Polar Research. | Yoon, Seung-Tae | School of Earth System Sciences, College of Natural Sciences, Kyungpook National University, Daegu, 41566, South Korea | 37015068400 | styoon@knu.ac.kr; | Ocean and Polar Research | 1598-141X | 45 | 3 | 0.07 | 2025-06-25 | 1 | Amundsen Sea; Circumpolar Deep Water; ice shelves melting; ocean-ice interaction | Amundsen Sea; Antarctic Ice Sheet; Antarctica; Southern Ocean; West Antarctic Ice Sheet; West Antarctica; glaciology; ice cover; ice shelf; ice thickness; ice-ocean interaction; melting; sea level change | Korean | Final | 2023 | 10.4217/opr.2023010 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Article | Revision and Duplication in Early Modern Plays: A Reevaluation of the "Minus" Hypothesis | In the printed texts of early modern plays, scholars have observed a number of lines bracketed by a set of duplicate lines. In 1918, J. Dover Wilson called this type of textual error a "repetition bracket" and argued that it is evidence for the insertion of additional text. In 1930, W. W. Greg adduced pieces of evidence in early modern playhouse manuscripts in support of Wilson's addition (or "plus") hypothesis, but he also proposed an omission (or "minus") hypothesis. However, Greg's footnoted reference to a single instance in The Second Maiden's Tragedy was his sole empirical evidence for the latter hypothesis. In this article, I examine Greg's evidence and review fifty-one extant early modern playhouse manuscripts to argue that Greg's omission hypothesis is untenable. Duplications in manuscripts are associated with false starts, marginal additions, or text on addition leaves. Based on thorough study of these manuscripts, I conclude that repetition brackets in early printings are a strong sign of revision and not omission. Included in an appendix is a list of all omission and addition markings in extant manuscripts. | Kim, Heejin | Kyungpook Natl Univ, Dept English, Daegu, South Korea | 57205485740 | PAPERS OF THE BIBLIOGRAPHICAL SOCIETY OF AMERICA | PAP BIBLIOGR SOC AM | 0006-128X | 2377-6528 | 117 | 3 | AHCI | HUMANITIES, MULTIDISCIPLINARY | 2023 | 0.4 | 0 | 2025-06-25 | 0 | 0 | English | 2023 | 2023-09-01 | 10.1086/726387 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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