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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Article | Content Analysis of the Photoelectric Effect Presented in Introductory Physics Textbooks | This study aimed to analyze the content of the photoelectric effect presented in introductory physics textbooks. Extracting the contents related to the photoelectric effect presented in six introductory physics textbooks widely used in Korea, the characteristics of the composition of the photoelectric effect contents were evaluated. Results show that the contents of the photoelectric effect in introductory physics textbooks differed depending on the textbook. In addition, based on the history of science related to the photoelectric effect, several textbooks did not include the history of science in the acceptance of the theory of the photoelectric effect. The photoelectric effect principle was primarily explained using the photon model, and the explanation based on the classical viewpoint, that is, the wave theory, was presented only in some textbooks. Moreover, several differences in the definition of photons and the quantum interpretation of experimental results were observed among textbooks. Furthermore, the implications for introductory physics education were discussed on the basis of the results of this study. © 2023 The Korean Physical Society. All rights reserved. | Lee, Bongwoo; Ha, Sangwoo; Jho, Hunkoog; Ji, Youngrae | Department of Science Education, Dankook University, Yongin, 16890, South Korea; Department of Physics Education, Kyungpook National University, Daegu, 41566, South Korea; Graduate School of Education, Dankook University, Yongin, 16890, South Korea; Department of Physics Education, Sunchon National University, Sunchon, 57922, South Korea | 57022535500; 55215468100; 56136159300; 55457190100 | yrji@scnu.ac.kr; | New Physics: Sae Mulli | 0374-4914 | 73 | 3 | 0.12 | 2025-06-25 | 1 | Configuration; Content analysis; History of science; Introductory physics textbook; Photoelectric effect | Korean | Final | 2023 | 10.3938/npsm.73.229 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Article | Contributing Factors to the Burden on Primary Family Caregivers of Stroke Survivors in South Korea | The purpose of this study is to identify the factors associated with the burden on primary family caregivers of stroke patients at home without care services. For this study, the Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) data were used. Of the total 8010 caregivers, 1133 family caregiver burden was assessed with the shortened Caregiver Burden Inventory (CBI) 3 months after stroke. Patient and caregiver-related factors affecting the heavier burden of caregivers were identified by comparing the heavier caregiver burden group and the lighter caregiver burden group, which divided according to the CBI scores. The 719 (63.5%) family caregiver cared for patients at home without care services. Logistic regression analysis showed that four or more comorbidities (p = 0.002), neurological impairment at early onset (p < 0.001), dependence on daily life (p < 0.001), aphasia (p = 0.024), and depression(p < 0.001) were associated with a heavier burden of care. According to the shortened CBI, caregivers tended to be concerned more about psychological stress than physical strain. The findings suggest the importance of proactively guiding the emotional support services to caregivers who are at high risk of the heavier burden of patient care. © 2023 by the authors. | Kwon, Bo Mi; Lee, Hyun Haeng; Sohn, Min Kyun; Kim, Deog Young; Shin, Yong-Il; Oh, Gyung-Jae; Lee, Yang-Soo; Joo, Min Cheol; Lee, So Young; Song, Min-Keun; Han, Junhee; Ahn, Jeonghoon; Chang, Won Hyuk; Lee, Jongmin; Kim, Yun-Hee | Department of Rehabilitation Medicine, Konkuk University School of Medicine, Seoul, 05030, South Korea; Department of Rehabilitation Medicine, Konkuk University School of Medicine, Seoul, 05030, South Korea; Department of Rehabilitation Medicine, College of Medicine, Chungnam National University, Daejeon, 35015, South Korea; Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, 03722, South Korea; Department of Rehabilitation Medicine, School of Medicine, Pusan National University Yangsan Hospital, Pusan National University, Yangsan-si, 50612, South Korea; Department of Preventive Medicine, School of Medicine, Wonkwang University, Iksan, 54538, South Korea; Department of Rehabilitation Medicine, Kyungpook National University School of Medicine, Kyungpook National University Hospital, Daegu, 41566, South Korea; Department of Rehabilitation Medicine, School of Medicine, Wonkwang University, Iksan, 54538, South Korea; Department of Rehabilitation Medicine, Jeju National University Hospital, Jeju National University College of Medicine l, Jeju-si, 63241, South Korea; Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwangju, 61469, South Korea; Department of Statistics, Hallym University, Chuncheon-si, 24252, South Korea; Department of Health Convergence, Ewha Womans University, Seoul, 03760, South Korea; Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Samsung Medical Center, Heart Vascular Stroke Institute, Sungkyunkwan University School of Medicine, Suwon, 06351, South Korea; Department of Rehabilitation Medicine, Konkuk University School of Medicine, Seoul, 05030, South Korea; Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Samsung Medical Center, Heart Vascular Stroke Institute, Sungkyunkwan University School of Medicine, Suwon, 06351, South Korea, Department of Health Science and Technology, Department of Medical Device Management and Research, Department of Digital Healthcare, SAIHST, Sungkyunkwan University, Suwon, 06351, South Korea | 57401993400; 57221571161; 7101840459; 55375583000; 55890990500; 7007056685; 57202952463; 56982599700; 57202327370; 55375416600; 57192890252; 8855402200; 35301717900; 57202882113; 57020121600 | leej@kuh.ac.kr;yun1225.kim@samsung.com; | International Journal of Environmental Research and Public Health | 1661-7827 | 20 | 3 | 0.45 | 2025-06-25 | 3 | caregiver burden; depression; functional dependence; intimacy; neurological impairment; primary caregiver | Caregivers; Emotions; Humans; Republic of Korea; Stroke; Survivors; South Korea; health care; health services; health worker; mental disorder; mental health; stroke; adult; aged; aphasia; Article; behavior assessment; caregiver; caregiver burden; caregiver burden inventory; cerebrovascular accident; cognitive defect; cohort analysis; comorbidity; controlled study; daily life activity; depression; emotional support; female; human; logistic regression analysis; major clinical study; male; mental stress; middle aged; onset age; patient care; physical stress; risk factor; South Korea; stroke survivor; cerebrovascular accident; emotion; psychology; South Korea; survivor | English | Final | 2023 | 10.3390/ijerph20032760 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | Conference paper | Cooperative Control Strategy of Shared Energy Storage System for Smart Grid: A Case Study of Campus Building Energy Management | With the advancement of technology in energy storage systems (ESS) coupled with photovoltaics (PV), research on energy management systems is actively being conducted. However, due to the high investment costs associated with ESS, shared ESS used by multiple consumers has emerged as a current solution. Additionally, the allocation of capacity in shared ESS must be carefully considered so that each consumer can maximize its utilization. Therefore, we propose a multi-agent deep reinforcement learning-based energy management system that considers cooperative sharing of ESS between consumers. Furthermore, we conducted two additional cases (fair capacity allocation and a single-agent case) to verify the cooperative agent's performance. Finally, from the result of the experiment, the proposed model has been shown to maximize cost reduction effectively compared with both other cases. © 2023 IBPSA.All rights reserved. | Pagri, Muhammad Ihza Febriyan; Hwang, Junhwa; Kim, Bowoo; Suh, Dongjun | Department of Convergence & Fusion System Engineering, Kyungpook National University, Sangju, 37224, South Korea; Department of Convergence & Fusion System Engineering, Kyungpook National University, Sangju, 37224, South Korea; Department of Convergence & Fusion System Engineering, Kyungpook National University, Sangju, 37224, South Korea; Department of Convergence & Fusion System Engineering, Kyungpook National University, Sangju, 37224, South Korea | 58041079000; 57223968394; 57219947521; 36613529600 | dongjunsuh@knu.ac.kr; | Building Simulation Conference Proceedings | 2522-2708 | 18 | 0 | 2025-06-25 | 0 | Cost reduction; Deep learning; Energy management; Energy management systems; Investments; Multi agent systems; Reinforcement learning; Smart power grids; 'current; Building energy managements; Campus buildings; Case-studies; Co-operative control; Control strategies; Investment costs; Photovoltaics; Smart grid; Storage systems; Energy storage | English | Final | 2023 | 10.26868/25222708.2023.1586 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | Article | Correlation between adolescents’ dietary safety management competency and value recognition, efficacy, and competency of convergence using dietary area: a descriptive study | Objectives: This study aimed to investigate the correlation between adolescents’ dietary safety management competency, value recognition, efficacy, and competency of convergence using the dietary area (CUDA). Methods: Data were collected from 480 middle and high school students in Daegu, Gyeongbuk and Seoul, Gyeonggi using a self-administered five-point Likert scale questionnaire from May to July 2021. A questionnaire was used to investigate dietary safety management competency, awareness of convergence, recognition of the benefits, efficacy, and competency of CUDA. Results: We conducted factor, reliability, correlation, and regression analyses using SPSS 25. The average scores for each factor were: dietary significance (3.68); dietary safety management knowledge (3.34); food selection and cooking (3.72); nutrition management (3.38); weight management (3.28); risk dietary management (3.13); CUDA interest (2.98); convergence necessity (3.50); benefits in specialized areas (3.31); benefits in everyday life (3.48); efficacy of science and technology convergence (3.35); convergence efficacy with humanities, social science, and arts (3.31); and CUDA competency (3.41). The score for interest in CUDA was lower than that for the recognition of CUDA benefits. Significant positive correlations were observed between all factors except between risk dietary management and both nutrition and weight management (P < 0.01). Interest in CUDA and recognition of the need for convergence exhibited a positive and significant effect on all factors of the perception of CUDA benefits and efficacy. The subgroup factors of dietary safety management competency and the recognition of CUDA had a positive effect on the CUDA competency (P < 0.001, R2 = 0.58). Conclusions: Strengthening dietary safety management competency and increasing the awareness of CUDA can enhance adolescents’ convergence competency. Therefore, CUDA and targeted education must be actively promoted among adolescents. © 2023 Korean Society of Community Nutrition. | Kim, Yunhwa; Lee, Yeon-Kyung | Center for Beautiful Aging, Kyungpook National University, Daegu, 41566, South Korea; Department of Food Science and Nutrition, Kyungpook National University, Daegu, 41566, South Korea | 56066693500; 16301462200 | yklee@knu.ac.kr; | Korean Journal of Community Nutrition | 2951-3146 | 28 | 4 | 0.21 | 2025-06-25 | 1 | adolescent; competency; convergence; dietary; recognition | Korean | Final | 2023 | 10.5720/kjcn.2023.28.4.317 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Article | Crataegus pinnatifida Bunge root extract induces apoptosis of murine lung carcinoma cells in vitro | This study sought to evaluate the anticancer effects of Crataegus pinnatifida Bunge root extract (CPE) on murine Lewis lung carcinoma cells (LLC1) in vitro. CPE treatment (2.5, 5, 10 μg/mL, 24 h) of LLC cells led to a dose-dependent decrease in cell viability, while CPE treatment did not have a cytotoxic effect on non-cancer cells (NIH/3T3). CPE affects LLC by flipping the plasma membrane and making the membrane more permeable; by flow cytometry, CPE-induced annexin V and propidium iodide positivity, indicating induction of apoptosis in LLC cells. In addition, CPE enhanced the expression of apoptotic proteins caspase-3 and poly (ADP-ribose) polymerase 1 (PARP-1). CPE upregulated the proapoptotic protein BCL-2-associated X while downregulating the anti-apoptotic protein B-cell lymphoma 2 (BCL-2), suggesting that CPE induces apoptosis via the mitochondrial pathway. Furthermore, CPE upregulated the phosphorylation of the mitogen activated protein kinase p38. In conclusion, the results suggest that CPE has an anticancer effect in LLC cells by inducing apoptosis via p38. © The Korean Society for Applied Biological Chemistry 2023. | Kwon, Minjeong; Chae, Jongbeom; Nam, Ju-Ock | Department of Food Science and Engineering, Kyungpook National University, Daegu, 41566, South Korea; Department of Food Science and Engineering, Kyungpook National University, Daegu, 41566, South Korea; Department of Food Science and Engineering, Kyungpook National University, Daegu, 41566, South Korea, Research institute of Tailored Food Technology, Kyungpook National University, Daegu, 41566, South Korea | 57547402100; 57204499421; 7201496105 | namjo@knu.ac.kr; | Journal of Applied Biological Chemistry | 1976-0442 | 66 | 0 | 2025-06-25 | 0 | Apoptosis; Caspase-3; Crataegus pinnatifida; Lung cancer; p38 | English | Final | 2023 | 10.3839/jabc.2023.041 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | Conference paper | Crowdsourced Wi-Fi Access Point Localization using Vertical Movement Detection | Precise indoor positioning requires building databases depending on applied location estimation techniques in general. This paper studies an automated framework to determine the locations of Wi-Fi access points (APs) using data from multiple mobile users. As mobile users only move vertically in certain points (e.g., stairs), the proposed framework detects vertical movements from air pressure measurements, extracts user trajectories on a target floor, and places the extracted trajectories between a pair of vertically movable points. In order to detect vertical movement, we assume the indoor trajectory starts on one floor and moves to another floor, resulting in more than 2 vertical movements. Finally, the AP locations are estimated using Wi-Fi signal strength measured along the placed user trajectories. The effectiveness of the proposed framework is verified under a practical indoor environment using an Android application. © 2023 IEEE. | An, Hyeonseon; Gu, Hayoung; Joo, Sumin; Choi, Jeongsik | Kyungpook National University, School of Electrical Engineering, Daegu, South Korea; Kyungpook National University, School of Electrical Engineering, Daegu, South Korea; Kyungpook National University, School of Electrical Engineering, Daegu, South Korea; Kyungpook National University, School of Electrical Engineering, Daegu, South Korea | 58783988000; 58783988100; 58783380600; 58534394200 | gustjs1882@knu.ac.kr; | Proceedings of the 2023 13th International Conference on Indoor Positioning and Indoor Navigation, IPIN 2023 | 2.27 | 2025-06-25 | 3 | AP localization; indoor positioning; pedestrian dead reckoning; received signal strength; site survey | Crowdsourcing; Indoor positioning systems; Location; Trajectories; Wireless local area networks (WLAN); Access point localization; Access points; Indoor positioning; Mobile users; Movement detection; Pedestrian dead reckonings; Point localization; Received signal strength; Site surveys; Vertical movement; Floors | English | Final | 2023 | 10.1109/ipin57070.2023.10332484 | 바로가기 | 바로가기 | ||||||||||||||||||
| ○ | Book chapter | Cubic-Regression and Likelihood Based Boosting GAM to Model Drug Sensitivity for Glioblastoma | Generalized additive models (GAM) being versatile and efficient do present some difficulties in model selection and inference based on context and fitting with linear smoothers. GAM is being extended to embed smooth functions of variables described by a parameter which governs curve smoothness or approximate forecast precision in a wide range of non-linear models. Boosted GAM offers smooth function estimates of covariate influence functions and estimated degrees of freedom. GAM boosting solves the problem of limiting explanatory elements to relatively few and choosing smoothing settings. The challenges of drug Sensitivity towards the Glioblastoma are modelled for tissue samples, using the proposed Cubic-Regression-based GAM, and further analyzed using boosted GAM approach. Various spline variations and smooth interaction functions have been used to examine the behavior of the GAM model. Similarly, different base-learners have been explored in boosted GAM, and a hyperparameter is tuned to analyze the model behavior. © 2023 Scrivener Publishing LLC. | Kumar, Satyawant; Biju, Vinai George; Lee, Ho-Kyoung; Mathew, Blessy Baby | Dept. of CSE, Kyungpook National University, Daegu, South Korea; Dept. of CSE, CHRIST, School of Engineering and Technology, Bangalore, India; Dept. of CSE, Kyungpook National University, Daegu, South Korea; Dept. of Biotechnology, Dayananda Sagar College of Engineering, Bangalore, India | 58029499800; 57190167356; 58647175100; 57190953919 | kumarsatyawant460@gmail.com; | Data Engineering and Data Science: Concepts and Applications | 0 | 2025-06-25 | 0 | boosted GAM; Cubic regression GAM; drug sensitivity; glioblastoma; selection of spline functions | English | Final | 2023 | 10.1002/9781119841999.ch8 | 바로가기 | 바로가기 | |||||||||||||||||||
| ○ | Article | Current-Voltage Characteristics and Photovoltaic Effect in VO2/GaN Heterostructures | Vanadium dioxide (VO2) films were prepared on the n-GaN layer at 600 ◦C and oxygen partial pressure of 10–20 mTorr using pulsed laser deposition. The VO2 films displayed flat surfaces with a roughness of 1.9–2.1 nm, and they were hetero-epitaxy ones with the (200) orientation on n-GaN (0002). With the increase of the temperature, the resistance of the samples exhibited metal-insulator transition behaviors with a resistance change of ∼104 times at TMI of ∼350 K. Current–voltage characteristics indicated that VO2/n-GaN heterojunctions correspond to semiconductor/semiconductor junctions displaying a rectification ratio of ∼100 below TMI, whereas they were metal/semiconductor junctions with a rectification ratio of 3–4 above TMI. When UV light was illuminated, VO2/n-GaN heterostructures clearly showed the photovoltaic effect and photocurrent switching behavior. The VO2/n-GaN heterostructure made at10 mTorr had a potential barrier of ∼1.07 eV, which was estimated from capacitance–voltage measurement. This study shows that the metal-insulator transition behavior can modify the interfacial properties of the VO2/n-GaN heterostructure. © 2023 The Korean Physical Society. All rights reserved. | Bae, Geungro; Han, Doohyuk; Dho, Joonghoe | Department of Physics, Kyungpook National University, Daegu, 41566, South Korea; Department of Physics, Kyungpook National University, Daegu, 41566, South Korea; Department of Physics, Kyungpook National University, Daegu, 41566, South Korea | 58250144000; 58248737800; 6602898623 | jhdho@knu.ac.kr; | New Physics: Sae Mulli | 0374-4914 | 73 | 3 | 0 | 2025-06-25 | 0 | I-V curve; Nitrides; Oxides; Photovoltaic; Schottky junction | Korean | Final | 2023 | 10.3938/npsm.73.203 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Conference paper | Cytogenetic comparison of Hibiscus syriacus with Hibiscus moscheutos by FISH and flow cytometry | Determination of chromosome number, nuclear DNA content, genome size, and ploidy level as well as information on cytogenetic characteristics are all prerequisite in modern plant breeding. The high number, small size, and similar morphology of mitotic chromosomes in Hibiscus species make it challenging to identify individual chromosomes. The goal of the study was to ascertain the chromosome number, number of 5S and 18S rDNA signals, as well as genome sizes, 2C-DNA content of H. syriacus and H. moscheutos. Two cultivars from each species ‘Shintaeyang’ and ‘Blue Bird’ for H. syriacus and ‘Luna White’ and ‘Luna Pink Swirl’ for H. moscheutos were selected for analyses. The root tip squash method was used to check the chromosomal numbers. The number of chromosomes we found were 84 for H. syriacus and 38 for H. moscheutos. 5S rDNA and 18S rDNA signals were detected by fluorescence in situ hybridization (FISH). H. syriacus and H. moscheutos had two 5S rDNA signals whereas four 18S rDNA were found in H. syriacus and six 18S signals were detected in H. moscheutos. The lengths of mitotic metaphase chromosomes ranged from 2.01 to 7.43 µm and 2.43 to 7.11 µm for H. syriacus ‘Shintaeyang’ and ‘Blue Bird’ respectively, and 2.91 to 5.23 µm and 2.21 to 5.47 µm for H. moscheutos ‘Luna White’ and ‘Luna Pink Swirl’ accordingly. The 2C-DNA content of H. syriacus was 4.02 and 4.18 pg, for ‘Blue Bird’ and ‘Shintaeyang’, respectively, whereas, H. moscheutos had nearly half and that amount was 2.06 and 2.04 pg for ‘Luna White’ and ‘Luna Pink Swirl’, respectively. These findings will contribute to the detailed cytogenetic assessment of Hibiscus and thus benefit plant breeding in this genus. © 2023 International Society for Horticultural Science. All rights reserved. | Deepo, D.M.; Lim, Ki Byung | Department of Horticultural Science, Kyungpook National University, Daegu, 41566, South Korea, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu, 41566, South Korea; Department of Horticultural Science, Kyungpook National University, Daegu, 41566, South Korea, Institute of Agricultural Science and Technology, Kyungpook National University, Daegu, 41566, South Korea | 57216909682; 7403175915 | Acta Horticulturae | 0567-7572 | 1383 | 3.3 | 2025-06-25 | 2 | 18S rDNA; 5S rDNA; cytogenetics; fluorescence in situ hybridization; Hibiscus; nuclear DNA content | English | Final | 2023 | 10.17660/actahortic.2023.1383.30 | 바로가기 | 바로가기 | ||||||||||||||||||
| ○ | ○ | Article | Cytogenetic Study and Pollen Viability of Phalaenopsis Queen Beer 'Mantefon' | Intergeneric and interspecific hybridization has been employed for the breeding of Phalaenopsis to transfer desirable traits between species, producing novel phenotypes with improved size, color, form, and flower-bearing ability. These characteristics are often enhanced; however, many of these hybrids are triploids and have reduced or complete sterility, for example, Phalaenopsis Queen Beer 'Mantefon', an important novelty-type cultivar in Asia, particularly in China, Japan, and Republic of Korea. Despite the increasing demand for the crop for ornamental purposes, little is known about its cytogenetics, which is essential for breeding and, consequently, crop improvement. In this study, karyotyping using fluorescence in situ hybridization, meiotic chromosome behavior analysis, pollen staining, and in vitro viability germination tests were performed to understand the cause of hybrid sterility and pollen abnormality in Phalaenopsis Queen Beer 'Mantefon' from a cytogenetic perspective. Viability tests revealed pollen infertility at all flower developmental stages, confirmed by the absence of pollen tube growth. Aberrant chromosomal behavior was observed in pollen mother cells (PMCs), frequently forming univalents, chromosomal bridges, and laggards during the entire meiotic process. PMCs were also divided irregularly into sporads with varying numbers of micronuclei, which may be responsible for pollen sterility in this cultivar. Altogether, the cytogenetic analyses provided insights into the pollen development of Phalaenopsis Queen Beer 'Mantefon' and the conceivable causes of its infertility. | Sevilleno, Samantha Serafin; An, Hye Ryun; Cabahug-Braza, Raisa Aone M.; Ahn, Yun-Jae; Hwang, Yoon-Jung | Sahmyook Univ, Dept Convergence Sci, Seoul 01795, South Korea; Rural Dev Adm, Natl Inst Hort & Herbal Sci, Floriculture Res Div, Wonju 55365, South Korea; Sahmyook Univ, Plant Genet & Breeding Inst, Seoul 01795, South Korea; Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea | park, jun yeon/GPX-5293-2022; Ahn, Yun-Jae/HII-3425-2022 | 57212649168; 55324789600; 58453620000; 57196473453; 50061210800 | samanthasevilleno20@gmail.com;hryun@korea.kr;raisaaone@gmail.com;yjahn0121@gmail.com;hyj@syu.ac.kr; | PLANTS-BASEL | 2223-7747 | 12 | 15 | 0.59 | 2025-06-25 | 3 | 3 | cytogenetics; FISH; micronucleus; orchid; pollen staining; sporads | MOLECULAR CYTOGENETICS; INTERSPECIFIC HYBRIDS; CHROMOSOME-NUMBERS; MEIOTIC BEHAVIOR; DISPERSAL UNITS; BRASSICA-NAPUS; MEADOW FESCUE; ORCHIDS; FERTILITY; HETEROCHROMATIN | cytogenetics; FISH; micronucleus; orchid; pollen staining; sporads | English | 2023 | 2023-08 | 10.3390/plants12152828 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | Article | Cytotoxic Activities on Human Ovarian Cancer Cell Lines by Neolignans and Diarylnonanoids from the Seed of Myristica fragrans Houtt. | Ovarian cancer is a primary global health concern, often diagnosed at advanced stages with limited treatment options and poor prognosis. Natural products have emerged as potential sources of safe and effective therapies. From the seeds of Myristica fragrans Houtt. (nutmeg), 24 compounds, including neolignans and diarylnonanoid derivatives, were isolated and structurally elucidated. The cytotoxic activities of these isolated metabolites against cisplatin-sensitive and resistant human ovarian cancer cell lines were evaluated. In particular, myrifragranone C (23) exhibited cytotoxicity against all test cancer cell lines A2780, TOV-112D, and SK-OV3 with IC50 values of 14.1, 16.9, and 33.4 µM, respectively. Furthermore, compound 23 induced the death of A2780 and SK-OV3 cancer cells via apoptosis. Western blotting revealed that compound 23 significantly increased the expression of cleaved caspase-3 and poly-ADP ribose polymerase and promoted apoptosis via the mitogenactivated protein kinase signaling pathway. Our findings may provide a preliminary understanding of the antiovarian cancer effect of the active compound myrifragranone C as a potential treatment using natural products. © 2023, Korean Society of Pharmacognosy. All rights reserved. | Phong, Nguyen Viet; Chae, Ha Yeong; Oanh, Vu Thi; Min, Byung Sun; Kwon, Mi Jeong; Kim, Jeong Ah | Vessel-Organ Interaction Research Center, VOICE (MRC), College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea, BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea; Vessel-Organ Interaction Research Center, VOICE (MRC), College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea, BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea; Vessel-Organ Interaction Research Center, VOICE (MRC), College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea, Biotechnology Department, Vietnam – Korea Institute of Science and Technology, Thach Hoa, Thach That, Hanoi, 10000, Viet Nam; College of Pharmacy, Drug Research and Development Center, Daegu Catholic University, Gyeongbuk, 38430, South Korea; Vessel-Organ Interaction Research Center, VOICE (MRC), College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea, BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea; Vessel-Organ Interaction Research Center, VOICE (MRC), College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea, BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea | 57205196739; 57344707400; 57218248175; 55663638200; 35278164800; 24722570900 | mjkwon94@knu.ac.kr;jkim6923@knu.ac.kr; | Natural Product Sciences | 1226-3907 | 29 | 3 | 0.65 | 2025-06-25 | 4 | Diarylnonanoid; Myristica fragrans; Neolignan; Nutmeg; Ovarian Cancer | caspase 3; Diarylnonanoid; natural product; neolignan; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; unclassified drug; apoptosis; apoptosis assay; Article; carbon nuclear magnetic resonance; chemical structure; cytotoxicity; flow cytometry; high performance liquid chromatography; human; human cell; IC50; MAPK signaling; medicinal plant; MTT assay; nuclear magnetic resonance; nutmeg; ovarian cancer cell line; ovary cancer; plant seed; Western blotting | English | Final | 2023 | 10.20307/nps.2023.29.3.171 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | Article | Cytotoxic compounds against adenocarcinoma alveolar epithelial A549 cells from Paeoniae Radix | It has been known that Paeoniae Radix (PR) contains monoterpene glycosides showing a variety of biological activities such as anti-spasmodic, anti-inflammatory, anti-viral, neuroprotectiveand sedative effects. This study aimed to find the cytotoxic compounds isolated from the dichloromethane (CH2Cl2)-and ethyl acetate-soluble fractions of PR. As results, thirteen compounds (1-13) were isolated and the chemical structures were identified. In addition, the human alveolar adenocarcinoma cell line (A549) was treated with isolated compounds to determine the cytotoxic effect via evaluation of cell viability. The reduction of A549 cell viability was shown as following order; gallic acid (8) > (2S)-naringenin (9) > methyl gallate (10) > 6'-O-benzoylpaeoniflorin (7) > palmitic acid (3). Especially, 7 did not show the cytotoxicity in the human lung fibroblast cell line (MRC-5). The effect of 7 on the cell viabilities in A549 and MRC-5 is firstly reported in this study. Further study is required to find out the cytotoxic mechanism and the selectivity for the cancer cells of 7 in detail. © 2023, Korean Society for Applied Biological Chemistry. All rights reserved. | Park, Ji Won; Shin, Sang-Eun; Park, Haewon; Kim, Jeong Ah; Yang, Eun-Ju; Song, Kyung-Sik | Research Institute of Pharmaceutical Science, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea; Research Institute of Pharmaceutical Science, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea; Research Institute of Pharmaceutical Science, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea; Research Institute of Pharmaceutical Science, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea; College of Pharmacy, Chung-Ang University, Seoul, 06974, South Korea; Research Institute of Pharmaceutical Science, College of Pharmacy, Kyungpook National University, Daegu, 41566, South Korea | 59871797200; 58493537100; 58494100900; 24722570900; 57191204368; 13310139000 | ejy125@cau.ac.kr;kssong@knu.ac.kr; | Journal of Applied Biological Chemistry | 1976-0442 | 66 | 1 | 0 | 2025-06-25 | 0 | 6'-O-Benzoylpaeoniflorin; A549; Cytotoxicity; Paeoniae Radix | Korean | Final | 2023 | 10.3839/jabc.2023.038 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Conference paper | D-MPQUIC: Optimizing Loss Detection in High RTT Variation Networks | With the development of the Internet, the number of users on mobile devices is increasing. However, mobile networks have a poor performance because of high round-trip time (RTT) variations. Much research has been conducted to overcome this, including active research on transport layer protocols. Google proposed a new transport protocol called QUIC and demonstrated that QUIC outperforms TCP in the real world. Furthermore, research on the multipath extension of QUIC (MPQUIC) is also being actively conducted. However, MPQUIC has poor performance in networks with high RTT variations caused by the weakness of the loss detection algorithm. In this paper, we improved the performance of MPQUIC by modifying MPQUIC's time-based loss detection algorithm. We confirmed that the download completion time decreased by 55.5% compared with the original MPQUIC. © 2023 IEEE. | Kim, Min-Ki; Cho, You-Ze | Kyungpook National University, School of Electronic and Electrical Engineering, Daegu, South Korea; Kyungpook National University, School of Electronic and Electrical Engineering, Daegu, South Korea | 58556690800; 7404469829 | yzcho@ee.knu.ac.kr; | International Conference on Ubiquitous and Future Networks, ICUFN | 2165-8528 | 2023-July | 0 | 2025-06-25 | 0 | Multipath QUIC; QUIC; RTT Variations; Transport Protocol | Mobile telecommunication systems; Detection algorithm; Loss detection; Multipath; Multipath QUIC; Poor performance; QUIC; Round-trip time variation; Round-trip-time; Time variations; Transport protocols; Signal detection | English | Final | 2023 | 10.1109/icufn57995.2023.10200515 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Article | Data-Driven Batch Processing for Parameter Calibration of a Sensor System | When modeling a sensor system mathematically, we assume that the sensor noise is Gaussian and white to simplify the model. If this assumption fails, the performance of the sensor model-based controller or estimator degrades due to incorrect modeling. In practice, non-Gaussian or non-white noise sources often arise in many digital sensor systems. Additionally, the noise parameters of the sensor model are not known in advance without additional noise statistical information. Moreover, disturbances or high nonlinearities often cause unknown sensor modeling errors. To estimate the uncertain noise and model parameters of a sensor system, this paper proposes an iterative batch calibration method using data-driven machine learning. Our simulation results validate the calibration performance of the proposed approach. © 2023, Korean Sensors Society. All rights reserved. | Lee, Kyuman | Department of Robot and Smart System Engineering, Kyungpook National University, School of Convergence 415, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu, 41566, South Korea | 57193932345 | klee400@knu.ac.kr; | Journal of Sensor Science and Technology | 1225-5475 | 32 | 6 | 0 | 2025-06-25 | 0 | Batch Processing; Data-Driven; Machine Learning; Parameter Calibration; Sensor System | Korean | Final | 2023 | 10.46670/jsst.2023.32.6.475 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Proceedings Paper | Declarative interfaces for HEP data analysis: FuncADL and ADL/CutLang | Analysis description languages are declarative interfaces for HEP data analysis that allow users to avoid writing event loops, simplify code, and enable performance improvements to be decoupled from analysis development. One example is FuncADL, inspired by functional programming and developed using Python as a host language. FuncADL borrows concepts from database query languages to isolate the interface from the underlying physical and logical schemas. The same query can be used to select data from different sources and formats and with different execution mechanisms. FuncADL is one of the tools being developed by IRIS-HEP for highly scalable physics analysis for the LHC and HL-LHC. FuncADL is demonstrated by implementing example analysis tasks designed by HSF and IRIS-HEP. Another language example is ADL, which expresses the physics content of an analysis in a standard and unambiguous way, independent of computing frameworks. In ADL, analyses are described in human-readable text files composed of blocks with a keyword-expression structure. Two infrastructures are available to render ADL executable: CutLang, a runtime interpreter written in C++; and adl2tnm, a transpiler converting ADL into C++ or Python code. ADL/CutLang are already used in several physics studies and educational projects, and are adapted for use with LHC Open Data. | Huh, C.; Proffitt, M.; Prosper, H. B.; Sekmen, S.; Sen, B.; Unel, G.; Watts, G. | Kyungpook Natl Univ, Daegu, South Korea; Univ Washington, Seattle, WA USA; Florida State Univ, Tallahassee, FL USA; Middle East Tech Univ, Ankara, Turkiye; Univ Calif Irvine, Irvine, CA USA | unel, gokhan/KFB-1065-2024; Sen, Beyzanur/KBB-2869-2024 | 58136665500; 57205755772; 59150153600; 24172042700; 57574189600; 6603681553; 57202558611 | 20TH INTERNATIONAL WORKSHOP ON ADVANCED COMPUTING AND ANALYSIS TECHNIQUES IN PHYSICS RESEARCH | 1742-6588 | 1742-6596 | 2438 | 0 | 2025-06-25 | 0 | 0 | Data handling; Functional programming; High energy physics; Python; Query languages; Query processing; C++ codes; Computing frameworks; Database query language; Description languages; Executables; Human-readable text; Performance; Physics analysis; Runtimes; Text file; C++ (programming language) | English | 2023 | 2023 | 10.1088/1742-6596/2438/1/012075 | 바로가기 | 바로가기 | 바로가기 |
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