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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Versatile use of ZnO interlayer in hybrid solar cells for self-powered near infra-red photo-detecting application | We investigate the possibility of shifting the absorption peak of the hybrid solar cell into the red to near infra-red (NIR) region using a ZnO optical spacer. Poly[2,6-(4,4-bis-(2-ethylhexyl)-4H-cyclopenta [2,1-b; 3,4-b']dithiophene)-alt-4,7(2,1,3-benzothiadiazole)] (PCPDTBT) exhibits a 700 nm wavelength peak absorption and is a low-bandgap polymer. Zinc oxide (ZnO) was used as an n-type semiconducting electron acceptor. The efficiency was enhanced by introducing a ZnO optical spacer layer. A finite-difference time-domain simulation was performed with the aim to extract the largest simulated short-circuit current density from the hybrid photovoltaic cell structure. Via the simulation, we also tuned the ZnO thickness to make the solar cell sensitive to the NIR wavelengths and thus obtained the optimal structures for various active layer thicknesses suitable for NIR absorption applications. This study aims to demonstrate the applicability of the PCPDTBT:ZnO hybrid solar cell as a multi-functional NIR absorber cum solar cell which has potential applications in energy harvesting window coating, NIR photodetector, and tandem solar subcell through the use of a ZnO optical layer to control the light-induced electric field distribution inside the device structure. (C )2019 Elsevier B.V. All rights reserved. | Kim, Jun Young; Vincent, Premkumar; Jang, Jaewon; Jang, Min Seok; Choi, Muhan; Bae, Jin-Hyuk; Lee, Changhee; Kim, Hyeok | Gyeongsang Natl Univ, ERI, Dept Semicond Engn, 501Jinjudaero, Jinju 52828, Gyeongnam, South Korea; Kyungpook Natl Univ, Sch Elect Engn, 80 Daehakro, Daegu 702701, South Korea; Korea Adv Inst Sci & Technol, Sch Elect Engn, 291 Daehak Ro, Daejeon 34131, South Korea; Seoul Natl Univ, Interuniv Semicond Res Ctr, Dept Elect & Comp Engn, 1 Gwanak Ro, Seoul 08826, South Korea; Univ Seoul, Dept Elect & Comp Engn, 163 Seoulsiripdaero, Seoul 02504, South Korea | Lee, Changhee/A-2471-2009; Vincent, Premkumar/C-3190-2019; Jang, Min Seok/A-2548-2016; Kim, Jung Kyu/C-3271-2012 | 57207790226; 57189221688; 57194107504; 55418264900; 7402093793; 35326180700; 36043031500; 57191718658 | jhbae@ee.knu.ac.kr;chlee7@snu.ac.kr;hyeok.kim@uos.ac.kr; | JOURNAL OF ALLOYS AND COMPOUNDS | J ALLOY COMPD | 0925-8388 | 1873-4669 | 813 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING | 2020 | 5.316 | 6.9 | 1.38 | 2025-06-25 | 20 | 20 | Hybrid solar cells; Optical spacer; Near-infrared organic-inorganic absorber; Optical modeling | ELECTRON-TRANSPORT; OXIDE NANOPARTICLES; SPECTRAL RESPONSE; HIGH-PERFORMANCE; POLYMER; LAYER; PHOTODETECTORS | Hybrid solar cells; Near-infrared organic-inorganic absorber; Optical modeling; Optical spacer | Electric fields; Energy harvesting; Finite difference time domain method; II-VI semiconductors; Infrared devices; Magnetic semiconductors; organic-inorganic materials; Oxide minerals; Photodetectors; Photoelectrochemical cells; Photovoltaic cells; Semiconducting zinc compounds; Shims; Solar absorbers; Structural optimization; Time domain analysis; Wide band gap semiconductors; Zinc oxide; 2 ,1 ,3-Benzothiadiazole; Finite difference time domain simulations; Hybrid photovoltaic cells; Hybrid solar cells; Optical modeling; Optical spacer; Organic-inorganic; Semiconducting electrons; Solar cells | English | 2020 | 2020-01-15 | 10.1016/j.jallcom.2019.152202 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | X-ray/proton and photoluminescence behaviors of Sm³⁺ doped high-density tungsten gadolinium borate scintillating glass | Sm-activated scintillating glasses with high WO3 concentration up to 42.5 mol% were studied in this work. The effects of Sm2O3 concentration on the density, absorption and various (photo-, X-ray induced-, proton- and temperature dependent-) luminescence properties have been monitored. The glasses possess a high density with maximum value around 6.18 g/cm(3). The glass samples show the several absorption peaks of visible light and near-infrared wavelength those confirm the Sm3+ ion existence in glass matrices. The Gd3+ -> Sm3+ energy transfer took place in glasses which resulted to the strongest emission around 600 nm ((4)G(5/2) -> H-6(7/2)) of Sm3+ in the photo-, X-ray induced- and proton luminescence spectra. The optimal doping concentration of Sm2O3 in WO3-Gd2O3-B2O3 glass is 1.0 mol% that performed the highest emission intensity in these three types of luminescence spectra. In 1.0 mol% doped glass, the decay time under pulse X-ray excitation was analyzed and found to be 0.27 ms. The temperature dependent luminescence in a range of 10 K-300 K of 1.0 mol% doped glass was measured via UV-laser excitation. The emission intensity of glass increased 3.76 times with the temperature decrease. In this work, the fabricated WO3-Gd2O3-B2O3 glasses doped with Sm2O3 show the strong visible luminescence under visible light, X-ray and proton excitation. The developed glass performs the potential for X-ray scintillator applications with integration mode using in the medical, industrial and security imaging inspection system. (C) 2020 Elsevier B.V. All rights reserved. | Wantana, N.; Kaewnuam, E.; Kim, H. J.; Kang, S. C.; Ruangtaweep, Y.; Kothan, S.; Kaewkhao, J. | Nakhon Pathom Rajabhat Univ, Fac Sci & Technol, Phys Program, Muang 73000, Nakhon Pathom, Thailand; Nakhon Pathom Rajabhat Univ, Ctr Excellence Glass Technol & Mat Sci CEGM, Muang 73000, Nakhon Pathom, Thailand; Muban Chombueng Rajabhat Univ, Fac Sci & Technol, Phys Program, Ratchaburi 70150, Thailand; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Chiang Mai Univ, Fac Associated Med Sci, Ctr Radiat Res & Med Imaging, Dept Radiol Technol, Chiang Mai 50200, Thailand | ; Kaewnaum, Eakgapon/JWO-6262-2024; Kim, Hong Joo/AAE-1178-2022 | 56267058700; 56267295300; 59051568100; 57191418531; 37108588700; 6507017165; 23974520300 | eakgapon_9@hotmail.com;jakrapong@webmail.npru.ac.th; | JOURNAL OF ALLOYS AND COMPOUNDS | J ALLOY COMPD | 0925-8388 | 1873-4669 | 849 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING | 2020 | 5.316 | 6.9 | 2.61 | 2025-06-25 | 46 | 48 | High-density glass; Glass scintillator; Luminescence | LUMINESCENT PROPERTIES; TRANSITION; DY3+; IONS; GD3+ | Glass scintillator; High-density glass; Luminescence | Energy transfer; Gadolinium compounds; Glass; Infrared devices; Laser excitation; Light; Medical imaging; Samarium compounds; Scintillation; Tungsten compounds; Luminescence properties; Luminescence spectrum; Near-infrared wavelength; Scintillating glass; Temperature decrease; Temperature dependent; UV laser excitation; Visible luminescence; X rays | English | 2020 | 2020-12-30 | 10.1016/j.jallcom.2020.156574 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A P3A-Type ATPase and an R2R3-MYB Transcription Factor Are Involved in Vacuolar Acidification and Flower Coloration in Soybean | The determination of flower color mainly depends on the anthocyanin biosynthesis pathway and vacuolar pH; however, unlike the former, the mechanism of vacuolar acidification in soybean remains uncharacterized at the molecular level. To investigate this mechanism, we isolated four recessive purple-blue EMS-induced flower mutants from the purple flower soybean cultivar, Pungsannamul. The petals of all the mutants had increased pH compared with those of wild Pungsannamul. One of the mutants had a single nucleotide substitution in GmPH4, a regulator gene encoding an MYB transcription factor, and the substitution resulted in a premature stop codon in its first exon. The other three mutants had nucleotide substitutions in GmPH5, a single new gene that we identified by physical mapping. It corresponds to Glyma.03G262600 in chromosome 3 and encodes a proton pump that belongs to the P-3A-ATPase family. The substitutions resulted in a premature stop codon, which may be a defect in the ATP-binding capacity of GmPH5 and possibly a catalytic inefficiency of GmPH5. The result is consistent with their genetic recessiveness as well as the high pH of mutant petals, suggesting that GmPH5 is directly involved in vacuolar acidification. We also found that the expression of GmPH5 and several putative "acidifying" genes in the gmph4 mutant was remarkably reduced, indicating that GmPH4 may regulate the genes involved in determining the vacuolar pH of soybean petals. | Sundaramoorthy, Jagadeesh; Park, Gyu Tae; Lee, Jeong-Dong; Kim, Jeong Hoe; Seo, Hak Soo; Song, Jong Tae | Kyungpook Natl Univ, Sch Appl Biosci, Daegu, South Korea; Kyungpook Natl Univ, Dept Biol, Daegu, South Korea; Seoul Natl Univ, Dept Plant Biosci, Seoul, South Korea | Sundaramoorthy, Jagadeesh/O-4027-2017; Kim, So-Young/JFS-7698-2023 | 56444549800; 56443287800; 40462075100; 7601377826; 26642769200; 57797134000 | jtsong68@knu.ac.kr; | FRONTIERS IN PLANT SCIENCE | FRONT PLANT SCI | 1664-462X | 11 | SCIE | PLANT SCIENCES | 2020 | 5.754 | 7.0 | 0.78 | 2025-06-25 | 14 | 12 | flower color; vacuolar acidification; H+ P-ATPase; GmPH5; GmPH4; soybean (Glycine max) | ANTHOCYANIN BIOSYNTHETIC-PATHWAY; PURPLE-BLUE FLOWER; P-ATPASE; PIGMENTATION; EVOLUTION; PETUNIA; GENETICS; BIOCHEMISTRY; FLAVONOIDS; PROTEINS | flower color; GmPH4; GmPH5; H<sup>+</sup> P-ATPase; soybean (Glycine max); vacuolar acidification | English | 2020 | 2020-11-30 | 10.3389/fpls.2020.580085 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | ASR Enhances Environmental Stress Tolerance and Improves Grain Yield by Modulating Stomatal Closure in Rice | Abscisic acid-, stress-, and ripening-induced (ASR) genes are involved in responding to abiotic stresses, but their precise roles in enhancing grain yield under stress conditions remain to be determined. We cloned a rice (Oryza sativa) ASR gene, OsASR1, and characterized its function in rice plants. OsASR1 expression was induced by abscisic acid (ABA), salt, and drought treatments. Transgenic rice plants overexpressing OsASR1 displayed improved water regulation under salt and drought stresses, which was associated with osmolyte accumulation, improved modulation of stomatal closure, and reduced transpiration rates. OsASR1-overexpressing plants were hypersensitive to exogenous ABA and accumulated higher endogenous ABA levels under salt and drought stresses, indicating that OsASR1 is a positive regulator of the ABA signaling pathway. The growth of OsASR1-overexpressing plants was superior to that of wild-type (WT) plants under paddy field conditions when irrigation was withheld, likely due to improved modulation of stomatal closure via modified ABA signaling. The transgenic plants had higher grain yields than WT plants for four consecutive generations. We conclude that OsASR1 has a crucial role in ABA-mediated regulation of stomatal closure to conserve water under salt- and drought-stress conditions, and OsASR1 overexpression can enhance salinity and drought tolerance, resulting in improved crop yields. | Park, Seong-Im; Kim, Jin-Ju; Shin, Sun-Young; Kim, Young-Saeng; Yoon, Ho-Sung | Kyungpook Natl Univ, Coll Nat Sci, Dept Biol, Daegu, South Korea; Kyungpook Natl Univ, BK21 Plus KNU Creat BioRes Grp, Sch Life Sci, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Dok Do & Ulleung Do, Daegu, South Korea; Kyungpook Natl Univ, Adv Bioresource Res Ctr, Daegu, South Korea | Shin, Sun-Young/AAH-9914-2019 | 56310974600; 57203324864; 54943706600; 35798433500; 7402990205 | kyslhh1228@hanmail.net;hsy@knu.ac.kr; | FRONTIERS IN PLANT SCIENCE | FRONT PLANT SCI | 1664-462X | 10 | SCIE | PLANT SCIENCES | 2020 | 5.754 | 7.0 | 2.73 | 2025-06-25 | 49 | 49 | abscisic acid; abscisic acid-; stress-; and ripening-induced genes; grain yield; salt and drought stress tolerance; stomatal closure; transgenic rice plant | ALFALFA MEDICAGO-SATIVA; ABSCISIC-ACID; SALT TOLERANCE; DROUGHT TOLERANCE; CONFERS DROUGHT; WATER-DEFICIT; HYDROGEN-PEROXIDE; MOLECULAR-CLONING; RESPONSIVE GENE; ABIOTIC STRESS | abscisic acid; abscisic acid-; and ripening-induced genes; grain yield; salt and drought stress tolerance; stomatal closure; stress-; transgenic rice plant | English | 2020 | 2020-02-14 | 10.3389/fpls.2019.01752 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Cathepsin K inhibition-induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x-mediated Bim protein stabilization | Cathepsin K (Cat K) is expressed in cancer cells, but the effect of Cat K on apoptosis is still elusive. Here, we showed that inhibition of Cat K sensitized the human carcinoma cells to anti-cancer drug through up-regulation of Bim. Inhibition of Cat K increased USP27x expression, and knock down of USP27x markedly blocked Cat K-induced up-regulation of Bim expression. Furthermore, inhibition of Cat K induced proteasome-dependent degradation of regulatory associated protein of mammalian target of rapamycin (Raptor). Down-regulation of Raptor expression increased mitochondrial ROS production, and mitochondria specific superoxide scavengers prevented USP27x-mediated stabilization of Bim by inhibition of Cat K. Moreover, combined treatment with Cat K inhibitor (odanacatib) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reduced tumor growth and induced cell death in a xenograft model. Our results demonstrate that Cat K inhibition enhances anticancer drug sensitivity through USP27x-mediated the up-regulation of Bim via the down-regulation of Raptor. | Seo, Seung Un; Woo, Seon Min; Kim, Min Wook; Lee, Hyun-Shik; Kim, Sang Hyun; Kang, Sun Chul; Lee, Eun-Woo; Min, Kyoung-jin; Kwon, Taeg Kyu | Keimyung Univ, Sch Med, Dept Immunol, 1095 Dalgubeoldaero, Daegu 42601, South Korea; KRIBB, Metab Regulat Res Ctr, Daejeon 34141, South Korea; Kyungpook Natl Univ, Coll Nat Sci, BK21 Plus KNU Creat BioRes Grp, Sch Life Sci,KNU Ctr Nonlinear Dynam, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Med, Det Pharmacol, Daegu 41566, South Korea; Daegu Univ, Dept Biotechnol, Gyongsan 38453, Gyeongbuk, South Korea; DGMIF, New Drug Dev Ctr, 80 Cheombokro, Daegu 41061, South Korea | Lee, Eun-Woo/AAP-9603-2020 | 57195411399; 57199873466; 57204766033; 16316010200; 57210450420; 8666884200; 7406966489; 7201466928; 7202206057 | kjmin@dgmif.re.kr;kwontk@dsmc.or.kr; | REDOX BIOLOGY | REDOX BIOL | 2213-2317 | 30 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2020 | 11.799 | 7.0 | 2.55 | 2025-06-25 | 38 | 38 | Apoptosis; Bim; Cathepsin K; USP27x; Mitochondria; Raptor | MAMMALIAN TARGET; CYSTEINE CATHEPSINS; MTOR; APOPTOSIS; KINASE; PHOSPHORYLATION; RESISTANCE; AUTOPHAGY; GROWTH; DEATH | Apoptosis; Bim; Cathepsin K; Mitochondria; Raptor; USP27x | Animals; Antineoplastic Agents; Bcl-2-Like Protein 11; Biphenyl Compounds; Cathepsin K; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Kidney Neoplasms; Male; Mice; Mitochondria; Protein Stability; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand; Ubiquitin-Specific Proteases; Xenograft Model Antitumor Assays; antineoplastic agent; BIM protein; cathepsin K; odanacatib; reactive oxygen metabolite; regulatory associated protein of mTOR; tumor necrosis factor related apoptosis inducing ligand; antineoplastic agent; BCL2L11 protein, human; BIM protein; biphenyl derivative; cathepsin K; CTSK protein, human; deubiquitinase; odanacatib; reactive oxygen metabolite; tumor necrosis factor related apoptosis inducing ligand; USP27X protein, human; animal cell; animal experiment; antineoplastic activity; Article; Caki cell; cancer cell; clinical evaluation; controlled study; down regulation; human; human cell; in vivo study; kidney carcinoma; male; mouse; nonhuman; priority journal; protein degradation; protein expression; protein function; protein stability; renal cell carcinoma cell line; signal transduction; tumor growth; upregulation; animal; cell proliferation; cell survival; chemistry; drug effect; drug potentiation; drug screening; gene expression regulation; HeLa cell line; kidney tumor; metabolism; mitochondrion; protein stability; tumor cell line | English | 2020 | 2020-02 | 10.1016/j.redox.2019.101422 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Clinical Course of Asymptomatic and Mildly Symptomatic Patients with Coronavirus Disease Admitted to Community Treatment Centers, South Korea | We evaluated the clinical course of asymptomatic and mildly symptomatic patients with laboratory-confirmed coronavirus disease (COVID-19) admitted to community treatment centers (CTCs) for isolation in South Korea. Of 632 patients, 75 (11.9%) had symptoms at admission, 186 (29.4%) were asymptomatic at admission but developed symptoms during their stay, and 371 (58.7%) remained asymptomatic during their entire clinical course. Nineteen (3.0%) patients were transferred to hospitals, but 94.3% (573/613) of the remaining patients were discharged from CTCs upon virologic remission. The mean virologic remission period was 20.1 days (SD +/- 7.7 days). Nearly 20% of patients remained in the CTCs for 4 weeks after diagnosis. The virologic remission period was longer in symptomatic patients than in asymptomatic patients. In mildly symptomatic patients, the mean duration from symptom onset to virologic remission was 11.7 days (SD +/- 8.2 days). These data could help in planning for isolation centers and formulating self-isolation guidelines. | Lee, Yong-Hoon; Hong, Chae Moon; Kim, Dae Hyun; Lee, Taek Hoo; Lee, Jaetae | Kyungpook Natl Univ Hosp, Daegu, South Korea; Kyungpook Natl Univ, Daegu, South Korea; Keimyung Univ, Dongsan Med Ctr, Daegu, South Korea | Lee, Jaetae/ABF-3980-2020 | 57199022948; 37050876700; 57203012896; 56122334300; 7601451907 | jaetae@knu.ac.kr; | EMERGING INFECTIOUS DISEASES | EMERG INFECT DIS | 1080-6040 | 1080-6059 | 26 | 10 | SCIE | IMMUNOLOGY;INFECTIOUS DISEASES | 2020 | 6.883 | 7.0 | 2.29 | 2025-06-25 | 43 | 42 | Adult; Asymptomatic Infections; Betacoronavirus; Community Health Centers; Comorbidity; Coronavirus Infections; Disease Progression; Female; Humans; Length of Stay; Male; Middle Aged; Pandemics; Patient Admission; Patient Transfer; Pneumonia, Viral; Real-Time Polymerase Chain Reaction; Republic of Korea; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Young Adult; adolescent; adult; aged; Article; asymptomatic disease; child; coronavirus disease 2019; disease course; electronic medical record; female; gastrointestinal symptom; headache; health center; hospital admission; human; major clinical study; male; middle aged; oxygen saturation; real time reverse transcription polymerase chain reaction; remission; respiratory tract disease; retrospective study; risk assessment; school child; Severe acute respiratory syndrome coronavirus 2; South Korea; thorax radiography; very elderly; asymptomatic infection; Betacoronavirus; comorbidity; complication; Coronavirus infection; disease exacerbation; length of stay; pandemic; patient transport; real time polymerase chain reaction; reverse transcription polymerase chain reaction; time factor; virus pneumonia; young adult | English | 2020 | 2020-10 | 10.3201/eid2610.201620 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942 | An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage. Dehydroascorbate reductase (DHAR, EC 1.8.5.1) catalyzes the glutathione-dependent reduction of oxidized ascorbate (dehydroascorbate) and contains a redox active site and glutathione binding-site. The DHAR gene is important in biological and abiotic stress responses involving reduction of the oxidative damage caused by ROS. In this study, transgenic Synechococcus elongatus PCC 7942 (TA) was constructed by cloning the Oryza sativa L. japonica DHAR (OsDHAR) gene controlled by an isopropyl beta-D-1-thiogalactopyranoside (IPTG)-inducible promoter (Ptrc) into the cyanobacterium to study the functional activities of OsDHAR under oxidative stress caused by hydrogen peroxide exposure. OsDHAR expression increased the growth of S. elongatus PCC 7942 under oxidative stress by reducing the levels of hydroperoxides and malondialdehyde (MDA) and mitigating the loss of chlorophyll. DHAR and glutathione S-transferase activity were higher than in the wild-type S. elongatus PCC 7942 (WT). Additionally, overexpression of OsDHAR in S. elongatus PCC 7942 greatly increased the glutathione (GSH)/glutathione disulfide (GSSG) ratio in the presence or absence of hydrogen peroxide. These results strongly suggest that DHAR attenuates deleterious oxidative effects via the glutathione (GSH)-dependent antioxidant system in cyanobacterial cells. The expression of heterologous OsDHAR in S. elongatus PCC 7942 protected cells from oxidative damage through a GSH-dependent antioxidant system via GSH-dependent reactions at the redox active site and GSH binding site residues during oxidative stress. | Kim, Young-Saeng; Park, Seong-Im; Kim, Jin-Ju; Boyd, Joseph S.; Beld, Joris; Taton, Arnaud; Lee, Kyoung-In; Kim, II-Sup; Golden, James W.; Yoon, Ho-Sung | Kyungpook Natl Univ, Res Inst Dok Do & Ulleung Do, Daegu, South Korea; Kyungpook Natl Univ, BK21 Plus KNU Creat BioRes Grp, Sch Life Sci, Daegu, South Korea; Kyungpook Natl Univ, Dept Biol, Daegu, South Korea; Univ Calif San Diego, Div Biol Sci, La Jolla, CA 92093 USA; Drexel Univ, Coll Med, Dept Microbiol & Immunol, Philadelphia, PA 19104 USA; Dongshin Univ, Biotechnol Ind Ctr, Naju, South Korea; Kyungpook Natl Univ, Adv Bio Resource Res Ctr, Daegu, South Korea | Beld, Joris/JMA-9778-2023 | 35798433500; 56310974600; 57203324864; 55832325900; 16303199600; 8738229700; 34872606600; 55477678200; 7201774677; 7402990205 | 92kis@hanmail.net;jwgolden@ucsd.edu;hsy@knu.ac.kr; | FRONTIERS IN PLANT SCIENCE | FRONT PLANT SCI | 1664-462X | 11 | SCIE | PLANT SCIENCES | 2020 | 5.754 | 7.0 | 0.39 | 2025-06-25 | 7 | 9 | antioxidants; antioxidant-related enzymes; cyanobacterium; dehydroascorbate reductase; oxidative stress | CONFERS ENHANCED TOLERANCE; DEHYDROASCORBATE REDUCTASE; S-TRANSFERASE; STRESS-TOLERANCE; MONODEHYDROASCORBATE REDUCTASE; FUNCTIONAL DIVERGENCE; OXIDATIVE STRESS; SUPEROXIDE-DISMUTASE; DEFENSE SYSTEM; ABSCISIC-ACID | antioxidant-related enzymes; antioxidants; cyanobacterium; dehydroascorbate reductase; oxidative stress | English | 2020 | 2020-03-03 | 10.3389/fpls.2020.00231 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Functional Insight of Nitric-Oxide Induced DUF Genes inArabidopsis thaliana | Advances in next-generation sequencing technologies facilitate the study of plant molecular functions in detail and with precision. Plant genome and proteome databases are continually being updated with large transcriptomic or genomic datasets. With the ever-increasing amount of sequencing data, several thousands of genes or proteins in public databases remain uncharacterized, and their domain functions are largely unknown. Such proteins contain domains of unknown function (DUF). In the present study, we identified 231 upregulated and 206 downregulated DUF genes from the available RNA-Seq-based transcriptome profiling datasets ofArabidopsisleaves exposed to a nitric oxide donor,S-nitroso-L-cysteine (CysNO). In addition, we performed extensivein silicoand biological experiments to determine the potential functions ofAtDUF569and to elucidate its role in plant growth, development, and defense. We validated the expression pattern of the most upregulated and the most downregulated DUF genes from the transcriptomic data. In addition, a loss-ofAtDUF569function mutant was evaluated for growth, development, and defense against biotic and abiotic stresses. According to the results of the study,AtDUF569negatively regulates biotic stress responses and differentially regulates plant growth under nitro-oxidative stress conditions. | Nabi, Rizwana Begum Syed; Tayade, Rupesh; Imran, Qari Muhammad; Hussain, Adil; Shahid, Muhammad; Yun, Byung-Wook | Kyungpook Natl Univ, Sch Appl Biosci, Lab Plant Funct Genom, Daegu, South Korea; Rural Dev Adm, Natl Inst Crop Sci, Dept Southern Area Crop Sci, Miryang, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Lab Plant Breeding, Daegu, South Korea; Abdul Wali Khan Univ, Dept Agr, Mardan, Pakistan | Hussain, Dr. Adil/K-6016-2018; Hussain, Adil/K-6016-2018; Shahid, Muhammad/AAE-9424-2020; Imran, Qari Muhammad/ABG-6074-2022; Tayade, Rupesh/AAM-9652-2021 | 57200232212; 57191753234; 55849263700; 41961162600; 59577718600; 8245123600 | bwyun@knu.ac.kr; | FRONTIERS IN PLANT SCIENCE | FRONT PLANT SCI | 1664-462X | 11 | SCIE | PLANT SCIENCES | 2020 | 5.754 | 7.0 | 2.05 | 2025-06-25 | 34 | 38 | Arabidopsis; transcriptome; DUF569; differentially expressed genes; nitro-oxidative stress | TYROSINE NITRATION; PSEUDOMONAS-SYRINGAE; ARABIDOPSIS-THALIANA; WIDE IDENTIFICATION; S-NITROSYLATION; CELL-DEATH; CYCLIC-GMP; TRANSCRIPTOME; SIGNAL; EXPRESSION | Arabidopsis; differentially expressed genes; DUF569; nitro-oxidative stress; transcriptome | English | 2020 | 2020-07-14 | 10.3389/fpls.2020.01041 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Letter | High Prevalence of Rickettsia raoultii and Associated Pathogens in Canine Ticks, South Korea | We studied the prevalence of tickborne pathogens in canine ticks, South Korea, during 2010-2015. Results revealed a high prevalence of the emerging pathogen Rickettsia raoultii. Dog ticks may be maintenance hosts for tickborne pathogens, suggesting the need to continually evaluate the potential public health threat posed by R. raoultii-infected ticks. | Seo, Min-Goo; Kwon, Oh-Deog; Kwak, Dongmi | Anim & Plant Quarantine Agcy, Gimcheon, South Korea; Kyungpook Natl Univ, Daegu, South Korea | ; Seo, Min-Goo/NQF-4335-2025 | 53982155300; 7402195886; 7007148758 | dmkwak@knu.ac.kr; | EMERGING INFECTIOUS DISEASES | EMERG INFECT DIS | 1080-6040 | 1080-6059 | 26 | 10 | SCIE | IMMUNOLOGY;INFECTIOUS DISEASES | 2020 | 6.883 | 7.0 | 0.66 | 2025-06-25 | 18 | 19 | Animals; Dogs; Prevalence; Republic of Korea; Rickettsia; Ticks; article; dog; infectious agent; nonhuman; prevalence; public health; Rickettsia raoultii; South Korea; tick; animal; epidemiology; genetics; prevalence; Rickettsia; South Korea | English | 2020 | 2020-10 | 10.3201/eid2610.191649 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Image-Based Machine Learning Characterizes Root Nodule in Soybean Exposed to Silicon | Silicon promotes nodule formation in legume roots which is crucial for nitrogen fixation. However, it is very time-consuming and laborious to count the number of nodules and to measure nodule size manually, which led nodule characterization not to be study as much as other agronomical characters. Thus, the current study incorporated various techniques including machine learning to determine the number and size of root nodules and identify various root phenotypes from root images that may be associated with nodule formation with and without silicon treatment. Among those techniques, the machine learning for characterizing nodule is the first attempt, which enabled us to find high correlations among root phenotypes including root length, number of forks, and average link angles, and nodule characters such as number of nodules and nodule size with silicon treatments. The methods here could greatly accelerate further investigation such as delineating the optimal concentration of silicon for nodule formation. | Chung, Yong Suk; Lee, Unseok; Heo, Seong; Silva, Renato Rodrigues; Na, Chae-In; Kim, Yoonha | Jeju Natl Univ, Dept Plant Resources & Environm, Jeju Si, South Korea; Korea Inst Sci & Technol, Smart Farm Res Ctr, Gangneung Si, South Korea; Kongju Natl Univ, Dept Hort, Yesan, South Korea; Univ Fed Goias, Inst Math & Stat, Goiania, Go, Brazil; Gyeongsang Natl Univ, Dept Agron, Jinju Si, South Korea; Kyungpook Natl Univ, Sch Appl Life Sci, Daegu, South Korea | Chung, Yong/V-6909-2019 | 36983850100; 57201773412; 35898345700; 59454592400; 56182390700; 57224866763 | kyh1229@knu.ac.kr; | FRONTIERS IN PLANT SCIENCE | FRONT PLANT SCI | 1664-462X | 11 | SCIE | PLANT SCIENCES | 2020 | 5.754 | 7.0 | 1.46 | 2025-06-25 | 19 | 20 | phenomics; root phenotype; nodule count; nodule size; legume; machine learning; image process; high-throughput phenotyping | FUNCTIONAL-CHARACTERIZATION; NITROGEN; TRAITS; GROWTH; SYSTEM; STRESS; SOIL; IDENTIFICATION; TRANSPORTERS; SEGMENTATION | high-throughput phenotyping; image process; legume; machine learning; nodule count; nodule size; phenomics; root phenotype | English | 2020 | 2020-10-28 | 10.3389/fpls.2020.520161 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension | The development of hypertension is associated with mitochondrial redox balance disruptions. NADP(+)-dependent isocitrate dehydrogenase 2 (IDH2) plays an important role in the maintenance of mitochondrial redox balance by producing mitochondrial NADPH, which is an essential cofactor in the reduction of glutathione (from GSSG to GSH) to reduced form of glutathione (GSH). We investigated the association of IDH2 between the development of prolonged high-fat diet (HFD)-induced hypertension. Idh2 gene-deleted (Idh2(-/-)) male mice and wild-type (Idh2(+/+)) littermates were fed either HFD or low-fat diet (LFD). Some mice were administrated with Mito-TEMPO, a mitochondria-specific antioxidant. HFD feeding increased blood pressure (BP) in both Idh2(-/-) mice and Idh2(+/+) mice. HFD-induced BP increase was greater in Idh2(-/-) than Idh2(+/+) mice. HFD intake decreased IDH2 activity, NADPH levels, and the GSH/(GSH + GSSG) ratio in the renal mitochondria. However, HFD intake increased mitochondrial ROS levels, along with the accompanying oxidative stress and damage. HFD intake increased angiotensin II receptor 1 type 1 mRNA levels in the kidneys and plasma renin and angiotensin II concentrations. These HFD-induced changes were more prominent in Idh2(-/-) mice than Idh2(+/+) mice. Mito-TEMPO mitigated the HFD-induced changes in both Idh2(-/-) and Idh2(+/+) mice, with greater effects in Idh2(-/-) mice than Idh2(+/+) mice. These results indicate that prolonged HFD intake disrupts the IDH2-NADPH-GSH-associated antioxidant system and activates the renin-angiotensin system in the kidney, leading to increased BP, suggesting that IDH2 is a critical enzyme in the development of hypertension and that the IDH2-associated antioxidant system could serve as a potential hypertension treatment target. | Noh, Mi Ra; Kong, Min Jung; Han, Sang Jun; Kim, Jee In; Park, Kwon Moo | Kyungpook Natl Univ, Cardiovasc Res Ctr, Sch Med, Dept Anat, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, BK21 Plus, Sch Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Keimyung Univ, Dept Mol Med, Sch Med, 1095 Dalgubeol Daero, Daegu 42601, South Korea | 14421357000; 57194730911; 57202122005; 36514766600; 8785448200 | kmpark@knu.ac.kr; | REDOX BIOLOGY | REDOX BIOL | 2213-2317 | 34 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2020 | 11.799 | 7.0 | 1.81 | 2025-06-25 | 33 | 32 | Isocitrate dehydrogenase 2; Hypertension; Mitochondria; Reactive oxygen species; Renin-angiotensin system | MITOCHONDRIAL OXIDATIVE STRESS; ANGIOTENSINOGEN GENE-EXPRESSION; REDOX BALANCE; DAMAGE; OBESITY; KIDNEY; INJURY; TRANSHYDROGENASE; PATHOPHYSIOLOGY; SENSITIVITY | Hypertension; Isocitrate dehydrogenase 2; Mitochondria; Reactive oxygen species; Renin-angiotensin system | Animals; Apoptosis; Diet, High-Fat; Hypertension; Isocitrate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; angiotensin II; angiotensin receptor; angiotensin receptor 1 type 1; glutathione disulfide; isocitrate dehydrogenase 2; messenger RNA; reactive oxygen metabolite; reduced nicotinamide adenine dinucleotide phosphate; renin; unclassified drug; isocitrate dehydrogenase; angiotensin blood level; animal cell; animal experiment; animal model; animal tissue; Article; controlled study; disease association; elevated blood pressure; enzyme deficiency; enzyme inhibition; gene deletion; gene expression; hypertension; isocitrate dehydrogenase 2 deficiency; kidney tissue; lipid diet; low fat diet; male; mitochondrion; mouse; nonhuman; oxidative stress; pathophysiology; plasma renin activity; priority journal; renin angiotensin aldosterone system; wild type mouse; adverse event; animal; apoptosis; C57BL mouse; genetics; hypertension; knockout mouse; lipid diet; metabolism | English | 2020 | 2020-07 | 10.1016/j.redox.2020.101548 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Peroxiredoxin 5 ameliorates obesity-induced non-alcoholic fatty liver disease through the regulation of oxidative stress and AMP-activated protein kinase signaling | Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease globally. NAFLD-which can develop into liver fibrosis, nonalcoholic steatohepatosis, cirrhosis, and hepatocellular carcinoma-is defined as an excess accumulation of fat caused by abnormal lipid metabolism and excessive reactive oxygen species (ROS) generation in hepatocytes. Recently, we reported that Peroxiredoxin 5 (Prx5) plays an essential role in regulating adipogenesis and suggested the need to further investigation on the potential curative effects of Prx5 on obesity-induced fatty liver disease. In the present study, we focused on the role of Prx5 in fatty liver disease. We found that Prx5 overexpression significantly suppressed cytosolic and mitochondrial ROS generation. Additionally, Prx5 regulated the AMP-activated protein kinase pathway and lipogenic gene (sterol regulatory element binding protein-1 and FAS) expression; it also inhibited lipid accumulation, resulting in the amelioration of free fatty acid-induced hepatic steatosis. Silence of Prx5 triggered de novo lipogenesis and abnormal lipid accumulation in HepG2 cells. Concordantly, Prx5 knockout mice exhibited a high susceptibility to obesity-induced hepatic steatosis. Liver sections of Prx5-deletion mice fed on a high-fat diet displayed Oil Red Ostained dots and small leaky shapes due to immoderate fat deposition. Collectively, our findings suggest that Prx5 functions as a protective regulator in fatty liver disease and that it may be a valuable therapeutic target for the management of obesity-related metabolic diseases. | Kim, Mi Hye; Seong, Jung Bae; Huh, Jae-Won; Bae, Yong Chul; Lee, Hyun-Shik; Lee, Dong-Seok | Kyungpook Natl Univ, Sch Life Sci, Plus KNU Creat BioRes Grp BK21, Daegu, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Sch Life Sci & Biotechnol, Daegu, South Korea; KRIBB, Natl Primate Res Ctr, Cheongju, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Anat & Neurobiol, Daegu, South Korea | 57193994930; 57202134219; 16645802900; 56377838800; 16316010200; 57210068061 | lee1@knu.ac.kr; | REDOX BIOLOGY | REDOX BIOL | 2213-2317 | 28 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2020 | 11.799 | 7.0 | 4.36 | 2025-06-25 | 67 | 69 | Peroxiredoxin 5; Hepatic steatosis; NAFLD; ROS; AMPK; SREBP-1 | HEPATIC STEATOSIS; PATHOGENESIS; ATHEROSCLEROSIS; MITOCHONDRIA; METABOLISM; MECHANISMS; MANAGEMENT; HEALTH; ROLES | AMPK; Hepatic steatosis; NAFLD; Peroxiredoxin 5; ROS; SREBP-1 | AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Disease Models, Animal; Gene Knockout Techniques; Hep G2 Cells; Humans; Lipid Metabolism; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peroxiredoxins; Signal Transduction; alanine aminotransferase; aspartate aminotransferase; cyclooxygenase 2; hydroxymethylglutaryl coenzyme A reductase kinase; inducible nitric oxide synthase; mitogen activated protein kinase; peroxiredoxin 5; reactive oxygen metabolite; sterol regulatory element binding protein 1; stress activated protein kinase; synaptophysin; tumor necrosis factor receptor superfamily member 6; hydroxymethylglutaryl coenzyme A reductase kinase; peroxiredoxin; PRDX5 protein, human; Prdx5 protein, mouse; alanine aminotransferase blood level; AMPK signaling; animal cell; animal experiment; animal model; animal tissue; Article; aspartate aminotransferase blood level; controlled study; disease predisposition; enzyme activity; Hep-G2 cell line; histopathology; human; human cell; immunohistochemistry; lipid diet; lipid metabolism; lipid storage; lipogenesis; male; mouse; nonalcoholic fatty liver; nonhuman; obesity; oxidative stress; priority journal; protein analysis; protein expression; regulatory mechanism; sequence analysis; staining; upregulation; Western blotting; adverse event; animal; complication; disease model; gene knockout; genetics; metabolism; nonalcoholic fatty liver; obesity; oxidative stress; signal transduction | English | 2020 | 2020-01 | 10.1016/j.redox.2019.101315 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Plastid Phylogenomics of Dendroseris (Cichorieae; Asteraceae): Insights Into Structural Organization and Molecular Evolution of an Endemic Lineage From the Juan Fernandez Islands | Dendroseris D. Don comprises 11 species endemic to the Juan Fernandez islands in Chile. They demonstrate spectacular and unusual growth forms of rosette trees with extremely variable morphology and occupy wide ecological ranges on the islands. These unique plants are now highly threatened with extinction with very small population sizes, typically consisting of 10 or fewer individuals in wild. Despite morphological and ecological divergence among species of Dendroseris, their monophyly has been supported in previous studies, but with little resolution among subgeneric groups. We assembled seven complete plastome sequences from seven species of Dendroseris, including representatives from three subgenera, and carried out comparative phylogenomic analyses. The plastomes are highly conserved in gene content and order, with size ranging from 152,199 to 152,619 bp and containing 130 genes (87 coding genes, 6 rRNA genes, and 37 tRNA genes). Plastid phylogenomic analyses based on both the complete plastome sequences and 81 concatenated coding genes only show Dendroseris nested within Sonchus sensu lato, and also that inter-subgeneric relationships are fully resolved. Subg. Phoenicoseris is resolved as sister to the remaining species of the genus and a sister relationship between the two subgenera Dendroseris and Rea. Ten mutation hotspots from LSC and SSC regions and variable SSRs are identified as potential chloroplast markers for future phylogenetic and phylogeographic studies of Sonchus and related groups. | Cho, Myong-Suk; Kim, Seon-Hee; Yang, JiYoung; Crawford, Daniel J.; Stuessy, Tod F.; Lopez-Sepulveda, Patricio; Kim, Seung-Chul | Sungkyunkwan Univ, Dept Biol Sci, Suwon, South Korea; Kyungpook Natl Univ, Res Inst Dok Do & Ulleung Do Isl, Daegu, South Korea; Univ Kansas, Dept Ecol & Evolutionary Biol, Lawrence, KS 66045 USA; Univ Kansas, Biodivers Inst, Lawrence, KS 66045 USA; Ohio State Univ, Dept Evolut Ecol & Organismal Biol, Columbus, OH 43210 USA; Univ Vienna, Dept Bot & Biodivers Res, Vienna, Austria; Univ Concepcion, Dept Bot, Concepcion, Chile | Kim, Seung-Chul/AAR-6157-2020 | 56326352700; 57196226213; 55193226000; 7403085620; 7003950083; 55588365400; 57214983739 | sonchus96@skku.edu; | FRONTIERS IN PLANT SCIENCE | FRONT PLANT SCI | 1664-462X | 11 | SCIE | PLANT SCIENCES | 2020 | 5.754 | 7.0 | 1.07 | 2025-06-25 | 19 | 19 | Asteraceae; adaptive radiation; plastome evolution; insular woodiness; Juan Ferná ndez Islands; critically endangered | SUBTRIBE SONCHINAE ASTERACEAE; CHLOROPLAST DNA; CHROMOSOME-NUMBERS; WOODY SONCHUS; LACTUCEAE; SEQUENCE; TOOLS; ANGIOSPERMS; POLLINATION; ANNOTATION | adaptive radiation; Asteraceae; critically endangered; insular woodiness; Juan Fernández Islands; plastome evolution | English | 2020 | 2020-11-05 | 10.3389/fpls.2020.594272 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Silicon Confers Soybean Resistance to Salinity Stress Through Regulation of Reactive Oxygen and Reactive Nitrogen Species | Salt stress is one of the major abiotic stressors that causes huge losses to the agricultural industry worldwide. Different strategies have been adopted over time to mitigate the negative impact of salt stress on plants and reclaim salt-affected lands. In the current study, we used silicon (Si) as a tool for salinity alleviation in soybean and investigated the influence of exogenous Si application on the regulation of reactive oxygen and reactive nitrogen species and other salt stress-related parameters of the treated plants. Our results revealed that the canopy temperature was much higher in sole NaCl-treated plants but declined in Si + NaCl-treated plants. Furthermore, the chlorophyll contents decreased with sole NaCl treatment, whereas Si + NaCl-treated plants showed improved chlorophyll contents. In addition, Si application normalized the photosynthetic responses, such as transpiration rate (E) and net photosynthesis rate (P-N) in salt-treated plants, and reduced the activity of ascorbate peroxidase and glutathione under salt stress. The expression levels of antioxidant-related genes GmCAT1, GmCAT2, and GmAPX1 started to decline at 12 h after addition of Si to NaCl-treated plants. Similarly, the S-nitrosothiol and nitric oxide (NO)-related genes were upregulated in the salt stress condition but reduced after Si supplementation. Si application downregulated genes associated with reactive oxygen species and reactive nitrogen species and reduced enzymatic and non-enzymatic antioxidants of the treated plants. Results of the current study conclude that Si mitigated the adverse effects of NaCl-induced stress by modulating the crosstalk between antioxidants and NO scavengers. It is suggested that Si may be used in agricultural systems for alleviating salt stress. | Chung, Yong Suk; Kim, Ki-Seung; Hamayun, Muhammad; Kim, Yoonha | Jeju Natl Univ, Dept Plant Resources & Environm, Jeju, South Korea; FarmHannong Ltd, Daejeon, South Korea; Abdul Wali Khan Univ, Dept Bot, Mardan, Pakistan; Kyungpook Natl Univ, Sch Appl Life Sci, Daegu, South Korea | Chung, Yong/V-6909-2019; Hamayun, Muhammad/B-1694-2010 | 36983850100; 24463202100; 59297330100; 57224866763 | kyh1229@knu.ac.kr; | FRONTIERS IN PLANT SCIENCE | FRONT PLANT SCI | 1664-462X | 10 | SCIE | PLANT SCIENCES | 2020 | 5.754 | 7.0 | 5.17 | 2025-06-25 | 65 | 72 | canopy temperature; chlorophyll content; carboxylation efficiency; water use efficiency; nitric oxide (NO) scavenger | SALT STRESS; OXIDATIVE STRESS; GROWTH-HORMONES; WATER-DEFICIT; RESPONSES; TOLERANCE; PLANTS; TRANSPORTER | canopy temperature; carboxylation efficiency; chlorophyll content; nitric oxide (NO) scavenger; water use efficiency | English | 2020 | 2020-02-13 | 10.3389/fpls.2019.01725 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | A Geostatistical Evolution Strategy for Subsurface Characterization: Theory and Validation Through Hypothetical Two-Dimensional Hydraulic Conductivity Fields | A novel approach that uses the covariance matrix adaptation evolution strategy in conjunction with geostatistical covariance functions and simultaneous ensemble Kalman filters is introduced to characterize the hydraulic conductivity fields of aquifers. To verify the performance, several similarity measures between the target and estimated fields are used, including the correlation coefficient, least absolute deviation, least squares, and cross-variance ratio. Three different cases are synthesized through validation with a small-scale domain (40 x 40), in which the hydraulic conductivity fields are stationary, nonstationary, and stationary with reduced prior information. According to these applications, the developed approach produces excellent estimations whether the field is stationary or nonstationary when the conditioning information is sufficient. With limited conditioning information, the performance of the estimation is slightly but not significantly lower. To validate the scalability, the developed approach is applied to larger domains (100 x 100, 150 x 150, and 200 x 200), and a modified approach based on principal components is used. According to this analysis, the developed approach requires low computational cost by making predictions with a limited number of forward-model runs and internal computations. Furthermore, the approach requires a small amount of prior information for the estimation. Based on these applications, this approach shows high potential to create cost-effective estimates that can be used as a reference for the current state-of-the-art geostatistical inversion approaches to improve subsurface characterization. | Park, Eungyu | Kyungpook Natl Univ, Dept Geol, Daegu, South Korea | 23995577700 | egpark@knu.ac.kr; | WATER RESOURCES RESEARCH | WATER RESOUR RES | 0043-1397 | 1944-7973 | 56 | 3 | SCIE | ENVIRONMENTAL SCIENCES;LIMNOLOGY;WATER RESOURCES | 2020 | 5.24 | 7.1 | 0.87 | 2025-06-25 | 12 | 12 | STEADY-STATE; INVERSE PROBLEM; ALGORITHM; TRANSMISSIVITY; HETEROGENEITY; TOMOGRAPHY; ADAPTATION; TRANSIENT; MODELS; SCALE | aquifer characterization; covariance matrix adaptation; ensemble Kalman filter; evolution strategy; geostatistical inversion approach; principal components | Aquifers; Computation theory; Cost effectiveness; Covariance matrix; Hydraulic conductivity; Hydrogeology; Optimization; Correlation coefficient; Covariance matrix adaptation evolution strategies; Ensemble Kalman Filter; Evolution strategies; Geostatistical inversion; Least absolute deviations; Principal Components; Subsurface characterizations; aquifer; geostatistics; hydraulic conductivity; Kalman filter; model validation; subsurface flow; two-dimensional modeling; Cost benefit analysis | English | 2020 | 2020-03 | 10.1029/2019wr026922 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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