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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Endoscopic management of pseudo-lumen stapling following laparoscopic esophagojejunostomy: A case report | Introduction: Pseudo-lumen stapling can occur following an incidental submucosal introduction of a fork of the linear stapler into the esophageal side during esophagojejunostomy (EJS) after total gastrectomy. This leaves a mucosa-covered layer over the EJS site that can eventually cause an obstruction. If it is noticed intraoperatively, an immediate surgical take-down and repeat anastomosis might be chosen by most surgeons. However, these procedures might have side effects such as further dissection into the esophageal hiatus and unnecessary tension on the anastomosis. To our knowledge, no existing publication has presented a non-surgical management method for pseudo-lumen stapling. Presentation of case: A 64-year-old male underwent laparoscopic total gastrectomy with a pseudo-lumen stapling unnoticed during surgery. Upon its recognition on the third postoperative day, endoscopic release of the tissue covering the anastomosis was performed. The procedure was successful. Gastrographic examination on the sixth postoperative day confirmed a good passage of the contrast agent. Postoperative one-year endoscopic examination confirmed patent anastomosis without stenosis. Discussion: Although pseudo-lumen stapling is one of the most unwanted consequences of EJS using linear staplers, there is little information or documentation available as reference for cases encountered during clinical practice. This might be related to the tendency of surgeons to perform an immediate take-down, followed by repeat EJS when this is noticed during surgery. We were able to successfully overcome this problem without surgery following a series of early gastrographic and endoscopic procedures. Conclusion: Endoscopic release of the covering tissue should be considered a valid non-surgical solution to pseudo-lumen stapling. | Lee, Seung Soo | Kyungpook Natl Univ Hosp, Dept Surg, 130 Dongdeok Ro, Daegu 41944, South Korea | 54400392100 | peterleess@hanmail.net; | INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS | INT J SURG CASE REP | 2210-2612 | 111 | ESCI | SURGERY | 2023 | 0.6 | 82.7 | 0.33 | 2025-06-25 | 1 | 1 | Case report; Endoscopy; Gastrectomy; Stomach neoplasms; Surgical staplers | TOTAL GASTRECTOMY; RESECTION | Case report; Endoscopy; Gastrectomy; Stomach neoplasms; Surgical staplers | contrast medium; abdominal radiography; adult; anastomosis; Article; case report; clinical article; endoscopic surgery; endoscopy; esophagojejunostomy; histopathology; human; human tissue; laparoscopic surgery; laparoscopic total gastrectomy; lymph node dissection; male; middle aged; stomach cancer; surgical stapling | English | 2023 | 2023-10 | 10.1016/j.ijscr.2023.108830 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | GCSB-5 regulates inflammatory arthritis and pain by modulating the mitogen-activated protein kinase signaling pathway in a murine model of rheumatoid arthritis | Objectives: This study aimed to determine whether GCSB-5 has anti-inflammatory and antinociceptive effects in mice with collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis (RA), and investigate the influence of GCSB-5 on the mitogen-activated protein kinase (MAPK) pathway.Materials and methods: The experimental animal study was designed to include five groups: CIA mice treated with GCSB-5 (300 mg/kg), GCSB-5 (600 mg/kg), celecoxib (60 mg/kg), or saline for four weeks, and nontreated control mice. The clinical severity of arthritis was scored. Nociceptive thresholds were measured by using a von Frey dynamic plantar analgesimeter. The MAPK pathway was evaluated in mouse synovium. The expression of channels associated with pain signaling was assessed by western blot and immunohistochemical staining.Results: GCSB-5 treatment diminished the severity of clinical arthritis and increased the nociceptive threshold in mice with CIA. Celecoxib, a positive control drug, also showed comparable changes. Clinical arthritis scores were inversely related to mechanical thresholds. GCSB-5 administration decreased the levels of anti-type II collagen antibody and inflammatory cytokines in the sera of mice with CIA. Furthermore, ERK, p38 MAPK, and JNK phosphorylation were downregulated and TRPV1 and ASIC3 expression were decreased in the synovium of GCSB-5-treated mice compared to saline-treated mice. Interleukin-6-induced TRPV1 and ASIC3 upregulation were also inhibited by GCSB-5 in human RA fibroblast-like synoviocytes in vitro. Conclusion: GCSB-5 decreased inflammatory arthritis and pain in a murine model of RA. The results present evidence that GCSB-5 may be beneficial for relieving pain as well as decreasing inflammation in autoimmune arthritis, such as RA. | Bang, Jihye; Kim, Gyeonghwa; Park, Soo Young; Jung, Hye Ra; Kim, Sang-Hyon; Kim, Ji -Min | Korea Natl Inst Hlth, Dept Chron Dis Convergence Res, Div Allergy & Resp Dis Res, Korea Dis Control & Prevent Agcy, Cheongju, South Korea; Keimyung Univ, Sch Med, Dept Internal Med, Div Rheumatol, Daegu, South Korea; Keimyung Univ, Inst Med Sci, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Keimyung Univ, Dept Pathol, Sch Med, Daegu, South Korea; Keimyung Univ, Sch Med, Dept Internal Med, Div Rheumatol, Daegu 42601, South Korea; Keimyung Univ, Inst Med Sci, Daegu 42601, South Korea | ; Kim, Gyeonghwa/AAQ-6424-2021; Park, Mi-Kyung/J-9643-2017 | 55806266700; 57195957884; 57191674344; 36189810600; 36470282200; 56646674500 | okjimin@kmu.ac.kr; | ARCHIVES OF RHEUMATOLOGY | ARCH RHEUMATOL | 2618-6500 | 38 | 4 | SCIE | RHEUMATOLOGY | 2023 | 1.1 | 83.3 | 0.6 | 2025-06-25 | 2 | 3 | Anti-inflammatory agents; ASIC3; plant extracts; rheumatoid arthritis; TRPV1 | RECEPTOR POTENTIAL VANILLOID-1; OSTEOARTHRITIS; EFFICACY; CELECOXIB; SAFETY; TRPV1 | Anti-inflammatory agents; ASIC3; plant extracts; rheumatoid arthritis; TRPV1 | acid sensing ion channel; celecoxib; collagen type 2; Freund adjuvant; gcsb 5 extract; interleukin 17; interleukin 6; interleukin 7; mitogen activated protein kinase 1; mitogen activated protein kinase 3; plant extract; stress activated protein kinase; unclassified drug; vanilloid receptor 1; animal experiment; animal model; animal tissue; antiinflammatory activity; antinociception; arthralgia; Article; collagen-induced arthritis; controlled study; enzyme linked immunosorbent assay; fibroblast; histology; immunization; immunohistochemistry; male; mammography; MAPK signaling; mouse; nonhuman; polyacrylamide gel electrophoresis; protein expression; protein phosphorylation; quality control; radioimmunoprecipitation; receptor down regulation; rheumatoid arthritis; synoviocyte; von Frey test; Western blotting | English | 2023 | 2023-12 | 10.46497/archrheumatol.2023.9643 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Fed and fasted bioequivalence assessment of two formulations of extended-release fixed-dose combination dapagliflozin/metformin (10/1,000 mg) tablets in healthy subjects | Two open-label, randomized, two-period crossover studies were conducted to investigate the pharmacokinetic (PK) properties, safety, and bioequivalence of the test formulation (KD4004), a new fixed-dose combination (FDC) formulation of dapagliflozin and metformin extended release (XR) tablets, relative to the reference formulation (10 mg dapagliflozin/1,000 mg metformin XR FDC tablet) in healthy subjects under fasting (Part A) and fed (Part B) conditions. After giving the dose, serial blood samples were collected for a period of 48 hours. Primary PK parameters (AUC0-t and Cmax) were used to assess bioequivalence between two dapagliflozin/metformin XR (10/1,000 mg) FDC formulations under fed and fasting conditions. Safety and tolerability were also evaluated. Part A and Part B were completed by 32 and 37 subjects, respectively. Bioequivalence of the two FDC formulations of dapagliflozin and metformin XR tablets was established in both the fasted and the fed conditions as the 90% confidence interval of the ratios of adjusted geometric means for AUC0-t and Cmax were contained within the predefined range of 0.800-1.250 bioequivalence criteria. Single-dose administration of dapagliflozin and metformin XR was safe and well tolerated as the two FDC formulations. In conclusion, both FDC formulations of dapagliflozin and metformin XR tablets were bioequivalent in fed and fasted subjects. All treatments were well tolerated.Trial Registration: Clinical Research Information Service Identifier: KCT0004026 | Lee, Hae Won; Kang, Woo Youl; Park, Ji Seo; Lee, Jae Hwa; Gwon, Mi-Ri; Yang, Dong Heon; Kim, Eun Hee; Park, Soo-Jin; Yoon, Young-Ran; Seong, Sook Jin | Kyungpook Natl Univ, Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Clin Pharmacol, 130 Dongdeok Ro, Daegu 41944, South Korea; Natl Inst Food & Drug Safety Evaluat, Dept Innovat Prod Support, Clin Trial Dossier Evaluat Team, Cheongju 28159, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Cardiol, Daegu 41944, South Korea; Catholic Univ Daegu, Coll Nursing, Gyongsan 38430, South Korea; Daegu Haany Univ, Coll Korean Med, Daegu 38610, South Korea; Kyungpook Natl Univ, Sch Med, Dept Mol Med, 130 Dongdeok Ro, Daegu 41944, South Korea | Yoon, Young-Ran/GLT-0172-2022 | 57202973823; 56816263900; 58164580000; 58165025100; 56035800800; 35277423400; 57203519526; 56563264400; 14629744500; 57211130049 | yry@knu.ac.kr;wintersj@knu.ac.kr; | TRANSLATIONAL AND CLINICAL PHARMACOLOGY | TRANSL CLIN PHARMACO | 2289-0882 | 2383-5427 | 31 | 2 | ESCI | PHARMACOLOGY & PHARMACY | 2023 | 1.1 | 83.5 | 0.28 | 2025-06-25 | 1 | 1 | Bioequivalence; Fixed-Dose Combination; Dapagliflozin; Metformin Extended Release; Type 2 Diabetes | TYPE-2 DIABETES-MELLITUS; SINGLE-COMPONENT DAPAGLIFLOZIN; GLYCEMIC CONTROL; METFORMIN; INHIBITION; MANAGEMENT | Bioequivalence; Dapagliflozin; Fixed-Dose Combination; Metformin Extended Release; Type 2 Diabetes | alanine aminotransferase; ammonium acetate; ammonium formate; bilirubin; dapagliflozin plus metformin; metformin; triacylglycerol; adult; area under the curve; Article; bilirubin blood level; bioequivalence; blood sampling; body mass; controlled study; crossover procedure; drug formulation; drug stability; drug tolerability; fasting; human; mass spectrometry; maximum concentration; non insulin dependent diabetes mellitus; open study; randomized controlled trial; single drug dose; ultra performance liquid chromatography | English | 2023 | 2023-06 | 10.12793/tcp.2023.31.e10 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | Management of sucking insect pests of tomato (Solanum lycopersicum) with insecticides and their impact on beneficial arthropods | The present study was carried out at the research field of the Department of Entomology, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh, during the tomato (Solanum lycopersicum L.) growing seasons of 2021 and 2022 to evaluate the pest management benefit of 4 insecticides, viz. Karate 2.5 EC (& lambda;-cyhalothrin), Ripcord 10 EC (cypermethrin), Marshal 20 EC (carbosulfan), and Shobicron 425 EC (profenofos Q + cypermethrin) against sucking insect pests (aphids, jassids, whiteflies and thrips) of tomato. The abundance of the sucking pests was significantly lower in the insecticide treated plots compared with the untreated control. During both the years, carbosulfan was the most effective insecticide against aphids (3.1 and 0.8 aphids/3 leaves, respectively), jassids (0.1 and 0.7 jassid/3 leaves, respectively), and thrips (1.9 and 1.1 thrips/3 leaves, respectively), whereas the profenofos Q cypermethrin decreased the abundance of whiteflies (1.4 and 2.0 whiteflies/3 leaves, respectively). However, these insecticides had negative effects on the pollinator insect and natural enemies of sucking pests in tomato fields. The insecticide-treated plots showed a significantly lower number of predators and pollinator than the untreated control plots. In the 1st and 2nd years, plots treated with cypermethrin (1.1 predators/plant) and & lambda;-cyhalothrin (1.2 predators/ plant), respectively, showed the highest abundance of predators. Among the insecticide-treated plots, profenofos Q cypermethrin treated plots showed the highest abundance of pollinator in both years (1st year: 0.7/ plot and 2nd year: 0.9/ plot). Carbosulfan treated plot showed the highest mean yield (58.7 tonnes/ha) with the highest marginal benefit-cost ratio (5.1). | Mondal, Ambika Rani; Miah, Ramiz Uddin; Miah, Yunus; Afroz, Mansura; Mazed, Khairul; Suh, Sang Jae; Amin, Ruhul | Bangabandhu Sheikh Mujibur Rahman Agr Univ, Gazipur, Bangladesh; Kyungpook Natl Univ, Daegu, South Korea | Amin, Md. Ruhul/KRP-9631-2024 | mramin@bsmrau.edu.bd; | INDIAN JOURNAL OF AGRICULTURAL SCIENCES | INDIAN J AGR SCI | 0019-5022 | 2394-3319 | 93 | 6 | SCIE | AGRICULTURE, MULTIDISCIPLINARY | 2023 | 0.3 | 83.7 | 2 | Marginal benefit-cost ratio; Pollinator; Predator; Sucking insects | BEMISIA-TABACI | English | 2023 | 2023-06 | 10.56093/ijas.v93i6.134069 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | Article | Characterization of complement C3 as a marker of alpha-amanitin toxicity by comparative secretome profiling | In the human body, proteins secreted into peripheral blood vessels are known as the secretome, and they represent the physiological or pathological status of cells. The unique response of cells to toxin exposure can be confirmed via secretome analysis, which can be used to discover toxic mechanisms or exposure markers. Alpha-amanitin (α-AMA) is the most widely studied amatoxin and inhibits transcription and protein synthesis by directly interacting with RNA polymerase II. However, secretory proteins released during hepatic failure caused by α-AMA have not been fully characterized. In this study, we analyzed the secretome of α-AMA-treated Huh-7 cells and mice using a comparative proteomics technique. Overall, 1440 and 208 proteins were quantified in cell media and mouse serum, respectively. Based on the bioinformatics results for the commonly downregulated proteins in cell media and mouse serum, we identified complement component 3 (C3) as a marker for α-AMA-induced hepatotoxicity. Through western blot in cell secretome and C3 ELISA assays in mouse serum, we validated α-AMA-induced downregulation of C3. In conclusion, using comparative proteomics and molecular biology techniques, we found that α-AMA-induced hepatotoxicity reduced C3 levels in the secretome. We expect that this study will aid in identifying new toxic mechanisms, therapeutic targets, and exposure markers of α-AMA-induced hepatotoxicity. © 2022, The Author(s) under exclusive licence to Korean Society of Toxicology. | Kim, Doeun; Lee, Min Seo; Sim, Hyunchae; Lee, Sangkyu; Lee, Hye Suk | BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea; BK21 Four-sponsored Advanced Program for SmartPharma Leaders, College of Pharmacy, The Catholic University of Korea, Bucheon, 14662, South Korea; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, South Korea; BK21 Four-sponsored Advanced Program for SmartPharma Leaders, College of Pharmacy, The Catholic University of Korea, Bucheon, 14662, South Korea | 57219650718; 57225079010; 57219098739; 57209046767; 35316111800 | sangkyu@knu.ac.kr;sianalee@catholic.ac.kr; | Toxicological Research | TOXICOL RES-GER | 1976-8257 | 2234-2753 | 39 | 2 | SCIE | TOXICOLOGY | 2023 | 1.6 | 84.4 | 0.42 | 2025-06-25 | 3 | Alpha-amanitin; Complement component 3; Exposure marker; Secretomes; Toxic mushroom | English | Final | 2023 | 10.1007/s43188-022-00163-z | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | Immunodysregulatory potentials of polyethylene or polytetrafluorethylene microplastics to mice subacutely exposed via intragastric intubation | Microplastics (MPs) have been recently recognized as posing a risk to human health. The adverse health effects of MP exposure have been recently reported, especially via the oral exposure route. The present study investigated whether subacute (4 week) exposure to polyethylene (PE) or polytetrafluorethylene (PTFE) MPs via gastric intubation caused immunotoxicity. Two different sizes of PE MPs (6.2 or 27.2 mu m) and PTFE MPs (6.0 or 30.5 mu m) were administered to 6-week-old mice of both sexes at 0 (corn oil vehicle control), 500, 1000, or 2000 mg/kg/day (n = 4/group). No significant differences were observed between groups in the major thymic or splenic immune cell populations, including thymic CD4(+), CD8(+), CD4(+)/CD8(+) T lymphocytes, and splenic helper T cells, cytotoxic T cells, and B cells. The ratio of interferon-gamma (IFN gamma) to interleukin-4 (IL-4) in culture supernatants from polyclonally activated splenic mononuclear cells ex vivo (48 h) was dose-dependently decreased in female mice that received small- and large-size PTFE MPs. The IFN gamma/IL-4 ratio was also decreased in the female mice dosed with large-size PE MPs. The serum IgG2a/IgG1 ratio was dose-dependently increased in male and female animals dosed with small-size PE MPs, in female animals dosed with large-size PTFE MPs, and in male animals dosed with small-size PTFE MPs. The present study implies that immune functions could be affected in animals exposed to MPs via gastric intubation. These effects are dependent on MP size, MP dose, MP polymer type, and mouse sex. Further investigations with longer exposure periods could be necessary to more clearly define the immunotoxic effects of MPs. | Jo, JiHun; Acharya, Manju; Bahadur, K. C. Pramod; Maharjan, Anju; Lee, DaEun; Gautam, Ravi; Kwon, Jung-Taek; Kim, KilSoo; Kim, ChangYul; Heo, Yong; Kim, HyoungAh | Daegu Catholic Univ, Coll Bio & Med Sci, Dept Occupat Hlth, Gyongsan, South Korea; Daegu Catholic Univ, Dept Toxicol, Grad Sch, Gyongsan, South Korea; Natl Inst Environm Res, Environm Hlth Res Dept, Incheon, South Korea; Daegu Gyeongbuk Med Innovat Fdn, Preclin Res Ctr, Daegu, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu, South Korea; Catholic Univ Korea, Coll Med, Dept Prevent Med, 222 Banpo Daero, Seoul 06591, South Korea | KC, Remant/AAT-8069-2020; Gautam, Ravi/AHA-0753-2022 | 57212005375; 57207357125; 58397322500; 57210824805; 57241720300; 57193066897; 57699585700; 35272034300; 56590694800; 36087239900; 56507727300 | kimha@catholic.ac.kr; | TOXICOLOGICAL RESEARCH | TOXICOL RES-GER | 1976-8257 | 2234-2753 | 39 | 3 | SCIE | TOXICOLOGY | 2023 | 1.6 | 84.4 | 0.7 | 2025-06-25 | 5 | 5 | Polyethylene; Polytetrafluorethylene; Microplastic toxicity; Immunotoxicity; Subacute intragastric administration | GUT MICROBIOTA | Immunotoxicity; Microplastic toxicity; Polyethylene; Polytetrafluorethylene; Subacute intragastric administration | English | 2023 | 2023-07 | 10.1007/s43188-023-00172-6 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Immunocytochemical localization of calbindin-D28K, calretinin, and parvalbumin in the Mongolian gerbil (Meriones unguiculatus) visual cortex | Introduction. While most animals of the Muridae family are nocturnal, the gerbil displays diurnal activity and provides a useful model for visual system research. The purpose of this study was to investigate the localization of calcium-binding proteins (CBPs) in the visual cortex of the Mongolian gerbil (Meriones unguiculatus). We also compared the labeling of CBPs to those of gamma-aminobutyric acid (GABA)- and nitric oxide synthase (NOS)-containing neurons. Material and methods. The study was conducted on twelve adult Mongolian gerbils (3-4 months old). We used horseradish peroxidase immunocytochemistry and two-color fluorescence immunocytochemistry with conventional and confocal microscopy to assess CBPs localization in the visual cortex. Results. The highest density of calbindin-D28K (CB)- (34.18%) and parvalbumin (PV)-IR (37.51%) neurons was found in layer V, while the highest density of calretinin (CR)-IR (33.85%) neurons was found in layer II. The CB- (46.99%), CR- (44.88%), and PV-IR (50.17%) neurons mainly displayed a multipolar round/oval morphology. Two-color immunofluorescence revealed that only 16.67%, 14.16%, and 39.91% of the CB-, CR-, and PV-IR neurons, respectively, contained GABA. In addition, none of the CB-, CR-, and PV-IR neurons contained NOS. Conclusions. Our findings indicate that CB-, CR-, and PV-containing neurons in the Mongolian gerbil visual cortex are distributed abundantly and distinctively in specific layers and in a small population of GABAergic neurons but are limited to subpopulations that do not express NOS. These data provide a basis for the potential roles of CBP-containing neurons in the gerbil visual cortex. | Son, Jae-Rim; Kuai, Xin-Yu; Jeon, Chang-Jin | Kyungpook Natl Univ, Dept Biol, Sch Life Sci, FOUR KNU Creat BioRes Grp BK21,Coll Nat Sci, Daegu, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Dok Do & Ulleungdo Isl, Daegu, South Korea | 58297007700; 58481008000; 7006894339 | cjjeon@knu.ac.kr; | FOLIA HISTOCHEMICA ET CYTOBIOLOGICA | FOLIA HISTOCHEM CYTO | 0239-8508 | 1897-5631 | 61 | 2 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CELL BIOLOGY | 2023 | 1.7 | 84.8 | 0.57 | 2025-06-25 | 3 | 2 | Mongolian gerbil; visual cortex; calcium-binding proteins; gamma-aminobutyric acid; NOS immunocytochemistry | NITRIC-OXIDE SYNTHASE; CALCIUM-BINDING PROTEINS; RETINAL GANGLION-CELLS; CENTRAL-NERVOUS-SYSTEM; IMMUNOREACTIVE NEURONS; EXPRESSING INTERNEURONS; SUPERIOR COLLICULUS; GLUTAMATE-RECEPTOR; SUPERFICIAL LAYERS; GABAERGIC NEURONS | calcium-binding proteins; gamma-aminobutyric acid; Mongolian gerbil; NOS immunocytochemistry; visual cortex | Animals; Calbindin 1; Calbindin 2; gamma-Aminobutyric Acid; Gerbillinae; Parvalbumins; Visual Cortex; 4 aminobutyric acid; calbindin 1; calretinin; nitric oxide synthase; parvalbumin; 4 aminobutyric acid; calbindin 1; calretinin; parvalbumin; animal cell; animal tissue; Article; cell structure; cell subpopulation; comparative study; confocal microscopy; controlled study; GABAergic transmission; horseradish peroxidase immunocytochemistry; immunocytochemistry; Meriones unguiculatus; nerve cell; nonhuman; protein localization; two color fluorescence immunocytochemistry; visual cortex; animal; gerbil | English | 2023 | 2023 | 10.5603/fhc.a2023.0010 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Insomnia during coronavirus disease 2019 pandemic in Korea: a National sleep survey | Coronavirus disease 2019 (COVID-19) pandemic has caused widespread increase in stress and affected sleep quality and quantity, with up to 30% prevalence of sleep disorders being reported after the declaration of the pandemic. This study aimed to assess perceived changes due to the pandemic in the prevalence of insomnia and excessive daytime sleepiness (EDS) in Korea, and identify the associated factors. An online survey was conducted among 4000 participants (2035 men and 1965 women) aged 20-69 years enrolled using stratified multistage random sampling according to age, sex, and residential area, between January, 2021 and February, 2022. The questionnaire included various items, such as socio-demographics, Insomnia Severity Index, and Epworth Sleepiness Scale (ESS). Insomnia was defined as difficulty falling asleep and difficulty maintaining sleep more than twice a week. EDS was classified as an ESS score >= 11. Insomnia was reported by 32.9% (n = 1316) of the participants (37.3% among women and 28.6% among men). Multivariate logistic regression revealed that insomnia was associated with female sex [odds ratio (OR) = 1.526, 95% confidence interval (CI) = 1.297-1.796], night workers (OR 1.561, 95% CI 1.160-2.101), and being unmarried (OR 1.256, 95% CI 1.007-1.566). EDS was reported by 12.8% (n = 510) of the participants (14.7% among men and 10.7% among women). EDS was associated with male sex (OR 1.333, 95% CI 1.062-1.674), and being employed (OR 1.292, 95% CI 1.017-1.641). During the COVID-19 pandemic, the prevalence of insomnia increased in Korea, while there was no significant change in EDS compared with pre-pandemic evidence. | Jeon, Ji-Ye; Kim, Keun Tae; Lee, Seo-Yong; Cho, Yong Won; Korean Sleep Res Soc | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurol, Daegu, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Neurol, Daegu, South Korea; Kangwon Natl Univ, Sch Med, Dept Neurol, Chunchon, South Korea; Kangwon Natl Univ, Interdisciplinary Grad Program Med Bigdata Converg, Chunchon, South Korea | ; LEE, SEJUE/KMX-1267-2024; Kim, Keun-Tae/AAV-5619-2021 | 57194943660; 57204465615; 58280501100; 55080335000 | neurocho@gmail.com; | SLEEP AND BIOLOGICAL RHYTHMS | SLEEP BIOL RHYTHMS | 1446-9235 | 1479-8425 | 21 | 4 | SCIE | CLINICAL NEUROLOGY;NEUROSCIENCES | 2023 | 1 | 84.8 | 1.18 | 2025-06-25 | 7 | 6 | COVID-19; Daytime sleepiness; Epidemiology; Insomnia; Sleep disturbance | EXCESSIVE DAYTIME SLEEPINESS; GENERAL-POPULATION; PREVALENCE; EPIDEMIOLOGY; DISORDERS; ANXIETY; STRESS | COVID-19; Daytime sleepiness; Epidemiology; Insomnia; Sleep disturbance | adult; aged; alcohol consumption; Article; awareness; coronavirus disease 2019; daytime somnolence; employment; Epworth sleepiness scale; excessive daytime sleepiness; female; health status; health survey; human; insomnia; Insomnia Severity Index; Korea; logistic regression analysis; major clinical study; male; marriage; modified insomnia severity index; multivariate analysis; multivariate logistic regression analysis; national sleep survey; night shift worker; pandemic; prevalence; questionnaire; residential area; satisfaction; single (marital status); sleep disorder; sleep latency; sleep pattern; sleep time; social media; sociodemographics; structured questionnaire; young adult | English | 2023 | 2023-10 | 10.1007/s41105-023-00464-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Titius-Bode's Relation in Exoplanetary Systems | The Titius-Bode's relation has been historically successful in predicting the location of Ceres in the solar system, while its physical basis remains hidden. In this study, we attempt to answer the question of whether the Titius-Bode's relation is universally valid for exoplanetary systems with plural exoplanets. For this purpose, we statistically study the distribution of the ratio of the orbiting periods of two planets in 32 exoplanetary systems hosted by a single star. We only consider the period ratios derived from exoplanets orbiting a single star since celestial objects under investigation are kept as simple as possible and free from uncertainties such as the mass of the host star. We find that the distribution of period ratios of two exoplanets appears inconsistent with that derived from the Titius-Bode's relation using the & chi;2 test. We also found that the distance distribution in exoplanetary systems unlikely follows the uniform distribution or the Poisson's distribution. It is noted, however, that more rigorous statistical tests should be carried out to reach a more certain conclusion. | Chang, Heon-Young | Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 41566, South Korea | 7407524806 | hyc@knu.ac.kr; | JOURNAL OF ASTRONOMY AND SPACE SCIENCES | J ASTRON SPACE SCI | 2093-5587 | 2093-1409 | 40 | 2 | ESCI | ASTRONOMY & ASTROPHYSICS | 2023 | 0.6 | 85.1 | 0 | 2025-06-25 | 0 | 0 | solar system; celestial mechanics; general | PLANETARY; LAW; COLLAPSE | celestial mechanics; general; solar system | English | 2023 | 2023-06 | 10.5140/jass.2023.40.2.67 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A preliminary study on the genesis of high-silica granite by incomplete separationof felsic cumulate-melt: leucocratic granites along the eastern contacts of theMiddle Yangsan Fault, South Korea | Granitic crystal mush consists of felsic cumulate and interstitial melt. Thus, the whole-rockcompositions of fully crystallized granite depend on the proportions of cumulus felsic minerals and interstitialmelt. Here, we (1) report the petrographic and whole-rock major and trace element elements characteristics of theMoa, Bomun and Dongcheon Granite occurring at the eastern contacts of the Middle Yangsan Fault, South Koreaand (2) provide a case that the geochemical proxies used in tectonic discrimination may reflect felsic cumulate-meltseparation rather than tectonic setting where the granites formed. Granitic rocks in the study area are subdividedinto biotite granite (Moa and Bomun Granite) and alkali-feldspar granite (Dongcheon Granite). They are leucocraticmonzogranite-syenogranite-alkali-feldspar granite on the basis of modal compositions. Feldspars and biotite inthe alkali-feldspar granite have more evolved composition than those in the biotite granite. These leucocraticgranites have extremely high silica contents (74-78 wt.%), showing a continuous calc-alkalic trend evolving fromthe magnesian metaluminous to ferroan peraluminous fields. The major and trace element elements characteristics suggest that the leucocratic high-silica granites are a product of granitic crystal mush in the shallow volcanic-arccrust. Our fractional crystallization models indicate that the biotite granite is felsic cumulate-dominant part whereasthe alkali-feldspar granite is frozen melt extracted from the crystallizing mush. | Park, Jongkyu; Jang, Yun-Deuk | Kyungpook Natl Univ, Dept Geol, Daegu 41566, South Korea; Korea Inst Geosci & Mineral Resources, Adv Geomat Res Dept, Daejeon 34132, South Korea; Kyungpook Natl Univ, Res Inst Dok Do & Ulleung Do Isl, Daegu 41566, South Korea | 57201402980; 7201869003 | jangyd@knu.ac.kr; | JOURNAL OF THE GEOLOGICAL SOCIETY OF KOREA | J GEOL SOC KOREA | 0435-4036 | 2288-7377 | 59 | 4 | ESCI | GEOSCIENCES, MULTIDISCIPLINARY | 2023 | 0.7 | 86.0 | 0 | 2025-06-25 | 0 | 0 | granite; crystal mush; felsic cumulate; melt extraction | U-PB AGES; TRACE-ELEMENTS; DEPOSITIONAL AGE; SE KOREA; ZIRCON; FLUORINE; DIFFERENTIATION; TERMINOLOGY; TEMPERATURE; RHYOLITES | crystal mush; felsic cumulate; granite; melt extraction | South Korea; biotite; crystal structure; crystallization; fractional crystallization; granite; tectonic setting; trace element | English | 2023 | 2023-12 | 10.14770/jgsk.2023.039 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Geomorphological process and the Quaternary fault displacement of alluvial fan terraces in the Eonyang area, Ulsan | The alluvial fans that formed continuously at the bottom of the Yangsan fault valley have experienced dissection over time, transforming into an alluvial fan terraces. By evaluating the formative age and displacement of Quaternary alluvial topographic surfaces such as fan terraces, the cumulative slip rate of the land surface influenced by fault movement after landform formation can be calculated. This study identified the geomorphological processes of the fan terrace in the Eonyang area of Ulsan and calculated the displacement and cumulative slip rate due to fault movement. Based on OSL age dating from sedimentary layers at four different fan terrace, it was suggested that the thrid and fourth fan terrace surfaces correspond to approximately 115 ka and 155 ka, respectively. This period is estimated to be highly related to the increased in the intensity of the East Asian summer monsoon. At the three alluvial terraces outcrops intersected by the fault line, the observed displacements of the topographic surfaces were consistently identified as characteristics of dextral strike-slip reverse faults. And after the formation of the fan terraces, the averaged horizontal and vertical cumulative slip rate was 0.087 m/ka and 0.006 m/ka, respectively. | Lee, Gwang-Ryul; Kim, Ju-Yeon; Lee, Haebin; Jeong, Ji Yun | Kyungpook Natl Univ, Dept Geog Educ, Teachers Coll, Daegu 41566, South Korea; Seoul Natl Univ, Teachers Coll, Dept Geog Educ, Seoul 08826, South Korea | 57288764300; 58764791700; 58764791800; 58764208200 | georiver@knu.ac.kr; | JOURNAL OF THE GEOLOGICAL SOCIETY OF KOREA | J GEOL SOC KOREA | 0435-4036 | 2288-7377 | 59 | 4 | ESCI | GEOSCIENCES, MULTIDISCIPLINARY | 2023 | 0.7 | 86.0 | 0.19 | 2025-06-25 | 1 | 1 | Yangsan fault; alluvial fan; fan terrace; fault valley; summer monsoon; slip rate | SOUTHERN YANGSAN FAULT; VARIABILITY; PLATEAU; PART; SEA | alluvial fan; fan terrace; fault valley; slip rate; summer monsoon; Yangsan fault | Ulsan; alluvial fan; fault displacement; geomorphology; land surface; landform; monsoon; Quaternary; slip rate; summer; terrace | English | 2023 | 2023-12 | 10.14770/jgsk.2023.044 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Process of fluvial terraces and evolution of stream during the late quaternary in the downstream of the Namhangang river | This study estimated the stream evolution process during the Late Quaternary in the downstream of the Namhangang River by analyzing the geomorphogical distribution, formation age and process of the fluvial terraces. Since the upper part of the downstream of the Namhangang River was mainly affected by ground uplifting adjacent to uplift axis of the central Korean Peninsula, stream incision has steadily occurred in the Late Quaternary. Therefore, fluvial terrace T2 formed in MIS 5 or 4 and fluvial terrace T2-r formed by reworking of deposits in MIS 3, have a high altitude above riverbed and are continuously distributed in the upper part. On the other hand, since the lower part of the downstream of the Namhangang River has a low altitude above sea level and is adjacent to coast, stream aggradation occurred in river valley during the periods of form MIS 5 to 4 and form MIS 3 to 2, when sea level had fallen. For this reason, it is estimated that the fluvial terrace T2 is buried under floodplain in the lower part. | Lee, Gwang-Ryul | Kyungpook Natl Univ, Dept Geog Educ, Teachers Coll, Daegu 41566, South Korea | 57288764300 | georiver@knu.ac.kr; | JOURNAL OF THE GEOLOGICAL SOCIETY OF KOREA | J GEOL SOC KOREA | 0435-4036 | 2288-7377 | 59 | 2 | ESCI | GEOSCIENCES, MULTIDISCIPLINARY | 2023 | 0.7 | 86.0 | 0 | 2025-06-25 | 0 | 0 | fluvial terrace; incision; valley fill; sea level change; uplift | INCISION RATES; BLACK-SEA; HOLOCENE; PLEISTOCENE; UPLIFT; PLAIN; GEOMORPHOLOGY; EXAMPLE; SYSTEM | fluvial terrace; incision; sea level change; uplift; valley fill | Korea; altitude; floodplain; Quaternary; reworking; sea level change; terrace; uplift; valley | English | 2023 | 2023-06 | 10.14770/jgsk.2023.014 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Relationship between maternal Group B Streptococcal colonization and gestational vaginal microbiome composition: A pilot study | Purpose: Group B Streptococcus (GBS) colonization and vaginal microbiome (VMB) dysbiosis are associated with adverse perinatal outcomes. However, the role of GBS colonization in maternal VMB remains unclear. Herein, we aimed to investigate this relationship and identify additional pathogens associated with GBS colonization for potential implications in understanding their clinical significance. Materials and methods: Vaginal swab samples were obtained before delivery from nine women with normal pregnancies for GBS detection and 16S rRNA gene sequencing. The diversity analysis and community state types clustering were used to compare the GBS-positive vs. GBS-negative groups. ANCOM-BC was implemented to identify differentially abundant microbes (DAMs) associated with GBS colonization. The correlation and receiver operating characteristic analysis were used to evaluate the relationship between DMAs and clinical parameters. Results: There were 6/9 (66,7%) GBS-negative pregnant women. The & alpha;-diversity index (p 1/4 0.71 for observed operational taxonomic units and p 1/4 0.90 for Shannon diversity), & beta;-diversity index (p 1/4 0.583), and community state types clustering (p 1/4 0.23) were not significantly different between the GBS-positive and-negative groups. Four DAMs, namely, Actinomyces, Shigella, Fenollaria, and Gemella, were significantly associated with GBS coloni-zation, reflecting the dynamicity of the gestational VMB. Their abundances were negatively correlated with birth weight and had acceptable discriminating ability in premature membrane rupture (area under the curve, 0.9). Conclusions: Despite the absence of significant effects on overall VMB composition, our preliminary results investigated that maternal GBS colonization related to high abundance of four pathogens with potential clinical utility as microbial signatures. | Le, Tan Minh; Choi, Yeseul; Nguyen, Hong Duc Thi; Lee, Donghyeon; Lee, Olive EM.; Chong, Gun Oh; Seong, Won Joon; Cha, Hyun-Hwa; Han, Hyung Soo | Kyungpook Natl Univ, Grad Sch, Dept Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, BK21 Four Program, Daegu 41944, South Korea; Kyungpook Natl Univ, Clin Om Inst, Daegu 41405, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Obstet & Gynecol, Daegu 41404, South Korea; Kyungpook Natl Univ, Sch Med, Dept Physiol, Daegu 41944, South Korea | ; Le, Tan/ITT-2150-2023 | 57870749600; 57226123444; 57870555300; 57870503500; 58029901300; 23099068000; 26656946000; 37033517800; 7401969388 | drleminhtan@knu.ac.kr;yeseul.choi830@knu.ac.kr;hongduc2307@knu.ac.kr;lowellkids24@knu.ac.kr;gochong@knu.ac.kr;wjseong@knu.ac.kr;chh9861@knu.ac.kr;hshan@knu.ac.kr; | INDIAN JOURNAL OF MEDICAL MICROBIOLOGY | INDIAN J MED MICROBI | 0255-0857 | 1998-3646 | 46 | SCIE | IMMUNOLOGY | 2023 | 1.4 | 86.5 | 0.39 | 2025-06-25 | 2 | 2 | Group B Streptococcus; Pregnant women; Vaginal microbiome; 16S rRNA | SILVA | 16S rRNA; Group B Streptococcus; Pregnant women; Vaginal microbiome | Female; Humans; Microbiota; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; RNA, Ribosomal, 16S; Streptococcal Infections; Streptococcus agalactiae; RNA 16S; Actinomyces; adult; Apgar score; area under the curve; Article; birth weight; clinical feature; clinical outcome; clinical significance; correlation analysis; diversity index; DNA extraction; female; Gemella; gestational age; human; human experiment; maternal age; metagenomics; microbial diversity; microbiome; nonhuman; normal human; obstetric delivery; operational taxonomic unit; outpatient department; pilot study; prediction; pregnancy; pregnant woman; preliminary data; premature rupture of membranes; quality control; receiver operating characteristic; RNA sequence; RNA sequencing; sensitivity and specificity; Shigella; vagina; vagina smear; genetics; microflora; pregnancy; pregnancy complication; Streptococcus agalactiae; Streptococcus infection | English | 2023 | 2023 (NOV-DEC) | 10.1016/j.ijmmb.2023.100426 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Topographical Analysis of Pacinian Corpuscle in the Pulp of Human Cadaver Finger Tip Pulp: A Pilot Cadaver Study | Background: The human hand is a specialised organ for fine motion and sensation and has a relatively large representation in the homunculus. The pathway of sensation starts from information sent by mechanoreceptors in the hand. This study reports the topography of the Pacinian corpuscle in the fingertips of a human cadaver.Methods: All 10 digits from both hands of a fresh-frozen cadaver were examined. Glabrous skin distal to the distal interphalangeal joint was harvested superficial to the periosteum including fat and subcutaneous tissue. The glabrous skin were divided into 10 sections that included five distal and five proximal sections. Modified gold chloride staining was performed. Sectioned specimens were observed under a light microscope and the density of Pacinian corpuscles was determined in each segment. The density of the corpuscles was compared between the radial/ulnar and proximal/distal segments and also between digits from the right hand versus those from the left hand.Results: Pacinian corpuscles were observed only in the subcutaneous tissue. There was no significant difference in density of the corpuscles between the distal and proximal segments or between the right and left hands. There was a statistically significant greater density of Pacinian corpuscles on the radial segments of all digits except the thumb.Conclusions: There is a greater density of Pacinian corpuscles on the radial side of the human fingertip in all digits except the thumb. | Lee, Hyun-Joo; Deslivia, Maria Florencia; Kholinne, Erica; Rhyu, Im Joo; Lee, Suk-Joong; Jeon, In-Ho | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthoped Surg, Daegu, South Korea; Kyungpook Natl Univ, Med Device & Robot Inst, Daegu, South Korea; Udayana Univ, Sanglah Hosp, Orthopaed & Traumatol Dept, Denpasar, Bali, Indonesia; Univ Trisakti, St Carolus Hosp, Fac Med, Dept Orthopaed Surg, Jakarta, Indonesia; Univ Ulsan, Asan Med Ctr, Dept Orthoped Surg, Seoul, South Korea; Korea Univ, Dept Anat, Coll Med, Seoul, South Korea; Gyeongsang Natl Univ, Sch Med, Dept Orthoped Surg, Chang Won, South Korea; Gyeongsang Natl Univ, Changwon Hosp, Chang Won, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Orthopaed Surg, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea | Deslivia, Maria Florencia/IAQ-9858-2023; Kholinne, Erica/AAI-7093-2020 | 58838750100; 56306551400; 57112598600; 55666938800; 57078230800; 7006505004 | jeonchoi@gmail.com; | JOURNAL OF HAND SURGERY-ASIAN-PACIFIC VOLUME | J HAND SURG-ASIAN-PA | 2424-8355 | 2424-8363 | 28 | 03 | ESCI | SURGERY | 2023 | 0.5 | 87.2 | 0.29 | 2025-06-25 | 1 | 1 | Finger; Pulp; Mechanoreceptor; Density; Pacinian corpuscle | RESPONSES; HAND | Density; Finger; Mechanoreceptor; Pacinian corpuscle; Pulp | Cadaver; Fingers; Hand; Humans; Pacinian Corpuscles; Thumb; gold chloride; adipose tissue; Article; finger; glabrous skin; human; interphalangeal joint; Pacini corpuscle; periosteum; pilot study; receptor density; staining; subcutaneous tissue; cadaver; hand; metabolism; thumb | English | 2023 | 2023-06 | 10.1142/s2424835523500455 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A new sawfly Cephalcia koreana (Hymenoptera: Pamphiliidae), the pest of Manchurian fir Abies holophylla in Korea | The genus Cephalcia Panzer in the sawfly family of Pamphiliidae Cameron is widely distributed in the Holarctic. However, very little is known about the Korean species. Here, we describe Cephalcia koreana Park & Jung, sp. nov. in Korea. Its larvae seriously defoliated leaves of Abies holophylla plantations in Hwacheon-gun, Gangwon Province during 2020-2022. It is newly recognized as an important forest insect pest. We provide taxonomic information including a new key for identifying and separating five Korean species and photographs of diagnostic characters with biological notes and genetic data of the new species. (c) 2023 National Science Museum of Korea (NSMK) and Korea National Arboretum (KNA), Publishing Services by Elsevier. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/). | Park, Bia; Nam, Youngwoo; Lee, Cha Young; Oh, Seungho; Jung, Jong-Kook | Kyungpook Natl Univ, Inst Phylogen & Evolut, Daegu 41566, South Korea; Natl Inst Forest Sci, Forest Entomol & Pathol Div, Seoul 02455, South Korea; Sahmyook Univ, Inst Environm & Ecol, Seoul 01795, South Korea; Yeungnam Univ, Environm Res Inst, Gyongsan 38541, South Korea; Kangwon Natl Univ, Dept Forest Environm Protect, Gangwon 24341, South Korea | ; Jung, Jongkook/MTE-0576-2025 | 57191834404; 7102722391; 55976314500; 55926922400; 55237828500 | jkjung@kangwon.ac.kr; | JOURNAL OF ASIA-PACIFIC BIODIVERSITY | J ASIA-PAC BIODIVERS | 2287-9544 | 16 | 4 | ESCI | BIODIVERSITY CONSERVATION | 2023 | 0.6 | 87.3 | 0 | 2025-06-25 | 0 | 0 | Cephalciinae; key; new pest; new species; Symphyta; web-spinning sawfly | Cephalciinae; key; new pest; new species; Symphyta; web-spinning sawfly | English | 2023 | 2023-12-01 | 10.1016/j.japb.2023.07.007 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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