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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Lemon Balm and Corn Silk Extracts Mitigate High-Fat Diet-Induced Obesity in Mice | Lemon balm and corn silk are valuable medicinal herbs, which exhibit variety of beneficial effects for human health. The present study explored the anti-obesity effects of a mixture of lemon balm and corn silk extracts (M-LB/CS) by comparison with the effects of single herbal extracts in high-fat diet (HFD)-induced obesity in mice. HFD supplementation for 84 days increased the body weight, the fat mass density, the mean diameter of adipocytes, and the thickness of fat pads. However, oral administration of M-LB/CS significantly alleviated the HFD-mediated weight gain and adipocyte hypertrophy without affecting food consumption. Of the various combination ratios of M-LB/CS tested, the magnitude of the decreases in weight gain and adipocyte hypertrophy by administration of 1:1, 1:2, 2:1, and 4:1 (w/w) M-LB/CS was more potent than that by single herbal extracts alone. In addition, M-LB/CS reduced the HFD-mediated increases in serum cholesterol, triglyceride, and low-density lipoprotein, prevented the reduction in serum high-density lipoprotein, and facilitated fecal excretion of cholesterol and triglyceride. Moreover, M-LB/CS mitigated the abnormal changes in specific mRNAs associated with lipogenesis and lipolysis in the adipose tissue. Furthermore, M-LB/CS reduced lipid peroxidation by inhibiting the HFD-mediated reduction in glutathione, catalase, and superoxide dismutase. Therefore, M-LB/CS is a promising herbal mixture for preventing obesity. | Cho, Il-Je; Kim, Sung-Eon; Choi, Beom-Rak; Park, Hye-Rim; Park, Jeong-Eun; Hong, Seong-Hwa; Kwon, Young-Sam; Oh, Won-Seok; Ku, Sae-Kwang | Daegu Haany Univ, Dept Herbal Prescript, Coll Korean Med, Gyongsan 38610, South Korea; Kyungpook Natl Univ, Dept Vet Surg, Coll Vet Med, Daegu 41566, South Korea; Nutracore Co Ltd, Gwanggyo SK Viewlake A-3206,Beobjo Ro 25, Suwon 16514, South Korea; Kyungpook Natl Univ, Dept Vet Internal Med, Coll Vet Med, Daegu 41566, South Korea; Daegu Haany Univ, Dept Anat & Histol, Coll Korean Med, Gyongsan 38610, South Korea | 36241202500; 57375231300; 56595969400; 56595786600; 57374589500; 57375011800; 7403459426; 35208796100; 7006331005 | skek023@dhu.ac.kr;owsvcs@hanmail.net;gucci200@hanmail.net; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 12 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 0.85 | 2025-07-30 | 10 | 11 | corn silk (stigma of Zea mays L; ); high-fat diet (HFD); lemon balm (Melisa officinalis L; mixture of lemon balm and corn silk extracts (M-LB; CS); obesity | ROSMARINIC ACID; METABOLIC HOMEOSTASIS; INSULIN-RESISTANCE; HEPATIC STEATOSIS; ADIPOSE-TISSUE; ALLANTOIN; LIVER; OFFICINALIS; MODEL; INFLAMMATION | Corn silk (stigma of Zea mays L.); High‐fat diet (HFD); Lemon balm (Melisa officinalis L.); Mixture of lemon balm and corn silk extracts (M‐LB/CS); Obesity | English | 2021 | 2021-12 | 10.3390/antiox10122015 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Review | Linking Oxidative Stress and Proteinopathy in Alzheimer's Disease | Proteinopathy and excessive production of reactive oxygen species (ROS), which are the principal features observed in the Alzheimer's disease (AD) brain, contribute to neuronal toxicity. beta-amyloid and tau are the primary proteins responsible for the proteinopathy (amyloidopathy and tauopathy, respectively) in AD, which depends on ROS production; these aggregates can also generate ROS. These mechanisms work in concert and reinforce each other to drive the pathology observed in the aging brain, which primarily involves oxidative stress (OS). This, in turn, triggers neurodegeneration due to the subsequent loss of synapses and neurons. Understanding these interactions may thus aid in the identification of potential neuroprotective therapies that could be clinically useful. Here, we review the role of beta-amyloid and tau in the activation of ROS production. We then further discuss how free radicals can influence structural changes in key toxic intermediates and describe the putative mechanisms by which OS and oligomers cause neuronal death. | Sharma, Chanchal; Kim, Sang Ryong | Kyungpook Natl Univ, Sch Life Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41944, South Korea | 57193577728; 56486163800 | chanchalmrt@gmail.com;srk75@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 8 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 2.74 | 2025-07-30 | 95 | 97 | proteinopathy; reactive oxygen species; Alzheimer's disease; amyloidopathy; tauopathy; oxidative stress | TRANSGENIC MOUSE MODEL; MILD COGNITIVE IMPAIRMENT; AMYLOID PRECURSOR PROTEIN; GLYCATION END-PRODUCTS; AMYOTROPHIC-LATERAL-SCLEROSIS; GUT-BRAIN AXIS; MITOCHONDRIAL DYSFUNCTION; LIPID-PEROXIDATION; PHOSPHORYLATED TAU; A-BETA | Alzheimer’s disease; Amyloidopathy; Oxidative stress; Proteinopathy; Reactive oxygen species; Tauopathy | English | 2021 | 2021-08 | 10.3390/antiox10081231 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Review | Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation | Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which leads to dermatitis, diarrhea, dementia, and possibly death depending on its severity and duration. Vitamin B3 is used in the synthesis of the NAD(+) family of coenzymes, contributing to cellular energy metabolism and defense systems. Although nicotinamide (niacinamide) is primarily used as a nutritional supplement for vitamin B3, its pharmaceutical and cosmeceutical uses have been extensively explored. In this review, we discuss the biological activities and cosmeceutical properties of nicotinamide in consideration of its metabolic pathways. Supplementation of nicotinamide restores cellular NAD(+) pool and mitochondrial energetics, attenuates oxidative stress and inflammatory response, enhances extracellular matrix and skin barrier, and inhibits the pigmentation process in the skin. Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials. Topically applied nicotinamide is well tolerated by the skin. Currently, there is no convincing evidence that nicotinamide has specific molecular targets for controlling skin aging and pigmentation. This substance is presumed to contribute to maintaining skin homeostasis by regulating the redox status of cells along with various metabolites produced from it. Thus, it is suggested that nicotinamide will be useful as a cosmeceutical ingredient to attenuate skin aging and hyperpigmentation, especially in the elderly or patients with reduced NAD(+) pool in the skin due to internal or external stressors. | Boo, Yong Chool | Kyungpook Natl Univ, Cell & Matrix Res Inst, BK21 Plus KNU Biomed Convergence Program, Dept Mol Med,Sch Med, Daegu 41944, South Korea | 6602899130 | ycboo@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 8 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 2.97 | 2025-07-30 | 109 | 115 | nicotinamide; niacinamide; vitamin B3; skin aging; pigmentation; cosmetic; cosmeceutical; metabolism; antioxidant; senescence; inflammation | REPLICATIVE LIFE-SPAN; PROTEASE-ACTIVATED RECEPTOR-2; MELANOSOME TRANSFER; TOPICAL NIACINAMIDE; OXIDATIVE STRESS; DOUBLE-BLIND; FACIAL HYPERPIGMENTATION; TRANEXAMIC ACID; EXTRACELLULAR-MATRIX; GENE-EXPRESSION | Antioxidant; Cosmeceu-tical; Cosmetic; Inflammation; Metabolism; Niacinamide; Nicotinamide; Pigmentation; Senescence; Skin aging; Vitamin B3 | English | 2021 | 2021-08 | 10.3390/antiox10081315 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Review | Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health | Oats (Avena sativa L.) are rich in protein, fiber, calcium, vitamins (B, C, E, and K), amino acids, and antioxidants (beta-carotene, polyphenols, chlorophyll, and flavonoids). beta-glucan and avenanthramides improve the immune system, eliminate harmful substances from the body, reduce blood cholesterol, and help with dietary weight loss by enhancing the lipid profile and breaking down fat in the body. beta-glucan regulates insulin secretion, preventing diabetes. Progladins also lower cholesterol levels, suppress the accumulation of triglycerides, reduce blood sugar levels, suppress inflammation, and improve skin health. Saponin-based avanacosidase and functional substances of flavone glycoside improve the immune function, control inflammation, and prevent infiltration in the skin. Moreover, lignin and phytoestrogen prevent hormone-related cancer and improve the quality of life of postmenopausal women. Sprouted oats are rich in saponarin in detoxifying the liver. The literatures have been reviewed and the recent concepts and prospects have been summarized with figures and tables. This review discusses recent trends in research on the functionality of oats rather than their nutritional value with individual immunity for self-medication. The oat and its acting components have been revisited for the future prospect and development of human healthy and functional sources. | Kim, Il-Sup; Hwang, Cher-Won; Yang, Woong-Suk; Kim, Cheorl-Ho | Kyungpook Natl Univ, Adv Bioresource Res Ctr, Daegu 41566, South Korea; Handong Global Univ, Global Leadership Sch, Pohang 37554, Gyeongsangbuk, South Korea; Nodaji Co Ltd, Pohang 37927, Gyeongsangbuk D, South Korea; SungKyunKwan Univ, Dept Biol Sci, Suwon 16419, Gyunggi, South Korea; Sungkyunkwan Univ, Samsung Adv Inst Hlth Sci & Technol SAIHST, Seoul 06351, South Korea | ; Kim, Cheorl-Ho/T-6753-2019 | 55477678200; 36787652900; 57069270500; 7409877266 | 92kis@hanmail.net;chowon@handong.edu;yangws91@naver.com;chkimbio@skku.edu; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 9 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 1.3 | 2025-07-30 | 41 | 55 | oat; Avena sativa L.; beta-glucan; avenanthramide; functionality; health benefit | BETA-GLUCAN; FAECALIBACTERIUM-PRAUSNITZII; NUTRITIONAL-VALUE; VITAMIN-E; FERMENTATION; FOOD; AVENANTHRAMIDES; GERMINATION; BARLEY; CONSUMPTION | Avena sativa L; Avenanthramide; Functionality; Health benefit; Oat; β-glucan | English | 2021 | 2021-09 | 10.3390/antiox10091454 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | NADPH Oxidase and Epidermal Growth Factor Receptor Are Promising Targets of Phytochemicals for Ultraviolet-Induced Skin Carcinogenesis | The skin acts as the primary defense organ that protects the body from the external environment. Skin cancer is one of the most common cancers in the world. Skin carcinogenesis is usually caused by cell degeneration due to exposure to ultraviolet (UV) radiation, which causes changes in various signaling networks, disrupting the homeostasis of single skin cells. In this review, we summarize the roles of nicotinamide adenine dinucleotide phosphate oxidase (NOX) and epidermal growth factor receptor (EGFR) in UV-induced skin carcinogenesis. Furthermore, we describe the crosstalk that exists between NOX, EGFR, and protein tyrosine phosphatase kappa and its oncogenic downstream signaling pathways. Chemoprevention is the use of chemical compounds to recover the healthy status of the skin or delay cancer development. Current evidence from in vitro and in vivo studies on chemopreventive phytochemicals that target NOX, EGFR, or both, as major regulators of skin carcinogenesis will also be discussed. | Kim, Min Jeong; Ha, Su Jeong; So, Bo Ram; Kim, Chang-Kil; Kim, Kyung-Min; Jung, Sung Keun | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Seoul Natl Univ, Dept Agr Biotechnol, Seoul 08826, South Korea; Kyungpook Natl Univ, Dept Hort Sci, Daegu KOREA;, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Div Plant Biosci, Coll Agr & Life Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu 41566, South Korea | Jung, SUNG KEUN/AGR-2623-2022; Kim, Kyung-Min Kim/C-7007-2014 | 57215818497; 56338753000; 57218122440; 7409880701; 34868260300; 35310491400 | minjeongkim@knu.ac.kr;igiihsj@snu.ac.kr;boram26@knu.ac.kr;ckkim@knu.ac.kr;kkm@knu.ac.kr;kjung04@knu.ac.kr;skjung04@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 12 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 0.39 | 2025-07-30 | 9 | 10 | nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase); epidermal growth factor receptor (EGFR); protein tyrosine phosphatase kappa (PTP kappa); reactive oxygen species (ROS) | INDUCED OXIDATIVE STRESS; REDOX REGULATION; CANCER-PATIENTS; EGFR; ACTIVATION; INFLAMMATION; FIBROBLASTS; INHIBITION; EXPRESSION; RADIATION | Epidermal growth factor receptor (EGFR); Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase); Protein tyrosine phosphatase κ (PTPκ); Reactive oxygen species (ROS) | English | 2021 | 2021-12 | 10.3390/antiox10121909 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Necrostatin-1 prevents ferroptosis in a ripk1-and ido-independent manner in hepatocellular carcinoma | Ferroptosis is caused by the iron-mediated accumulation of lipid peroxidation, which is distinct from apoptosis and necroptosis. Necrostatin-1 inhibits receptor-interacting serine/threonine-protein kinase 1 (RIPK1) to initiate necroptosis; it also inhibits indoleamine 2,3-dioxygenase (IDO) to regulate tumor immunity. However, few studies have examined the off-target effect of necrostatin-1 on the ferroptosis pathway. The present study examined whether necrostatin-1 could interrupt ferroptosis induced by system xc-inhibitors (sulfasalazine and erastin) and a glutathione peroxidase 4 inhibitor (RSL3) in Huh7 and SK-HEP-1 cells. Necrostatin-1 completely prevented decreases in cell viability induced by sulfasalazine and erastin; it partially blunted decreases in cell viability induced by RSL3. Necrostatin-1, ferrostatin-1, and deferoxamine repressed sulfasalazine-provoked membrane permeabilization, as detected by 7-aminoactinomycin D staining and lipid peroxidation measured using a C11-BODIPY probe. However, other RIPK1 inhibitors (necrostatin-1s and GSK2982772) and an IDO inhibitor (1-methyl-D-tryptophan) did not recover the decrease in cell viability induced by sulfasalazine. Necrostatin-1 potentiated sulfasalazine-induced expression of xCT, a catalytic subunit of system xc-in these cells. These results demonstrated that necrostatin-1 blocked ferroptosis through a mechanism independent from RIPK1 and IDO inhibition in Huh7 and SK-HEP-1 cells, indicating that its antioxidant activity should be considered when using necrostatin-1 as a RIPK1 inhibitor. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. | Yuk, Hanna; Abdullah, Md; Kim, Do-Hyung; Lee, Haeseung; Lee, Seung-Jin | College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34134, South Korea, Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu, 41566, South Korea; College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34134, South Korea; College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34134, South Korea; College of Pharmacy, Pusan National and University, Busan, 46241, South Korea; College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 34134, South Korea | 57221800203; 57220109439; 57194348591; 55706759800; 57192521570 | s.j.lee@cnu.ac.kr; | Antioxidants | ANTIOXIDANTS-BASEL | N/A | 2076-3921 | 10 | 9 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 3.02 | 2025-07-30 | 44 | Bioinformatics; Ferroptosis; Lipid peroxi-dation; Necroptosis; Necrostatin-1; Oxidative stress; RIPK1; SLC7A11; System x<sub>c</sub><sup>−</sup> | English | Final | 2021 | 10.3390/antiox10091347 | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | Over-Expression of Chorismate Mutase Enhances the Accumulation of Salicylic Acid, Lignin, and Antioxidants in Response to the White-Backed Planthopper in Rice Plants | The white-backed planthopper (WBPH) is a serious pest of rice crop and causes sever yield loss each year, especially in Asian countries. In this study, we used chorismate mutase (CM) transgenic line to examine the defense mechanism of rice plants against WBPH. The survival rate of WBPHs, infestation rate of plants, lignin biosynthesis, transcriptional regulation of related genes, salicylic acid (SA) accumulation and signaling and antioxidants regulation were investigated. The WBPH population decreased by 67% in OxCM-t, and the plant infestation rate was 3.5-fold higher in wild-type plants compared with transgenic plants. A substantial increase in lignin was found in the transgenic line (742%) and wild-type (417%) plants. Additionally, CM, phenylalanine ammonia lyase (PAL), chalcone synthase (CHS), and chalcone isomerase (CHI) showed significant increases in their relative expression level in the transgenic line. Salicylic acid was significantly enhanced in the transgenic line compared with WBPH infestation. SA can activate pathogenesis related proteins-1 (PR1), PR2, antioxidants, and the expression of their related genes: superoxide dismutase (SOD) and catalase (CAT). WBPH infestation reduced the chlorophyll contents of both transgenic and wild-type plants, but the reduction was great in wild-type than transgenic plants. The sugar content was only significantly increased in the transgenic line, indicating that sugars are not heavily involved in WBPH stress. Phenylalanine, proline, aspartic acid, and total amino acids were increased in the transgenic line and reduced in the wild-type plants. Taken together, all the results suggest that overexpression of CM gene regulates the defense mechanisms and enhances the rice toward WBPH stress. | Jan, Rahmatullah; Khan, Muhammad Aaqil; Asaf, Sajjad; Lubna; Lee, In-Jung; Kim, Kyung-Min | Kyungpook Natl Univ, Sch Appl Biosci, Div Plant Biosci, Coll Agr & Life Sci, 80 Dahak ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Costal Agr Res Inst, 80 Dahak Ro, Daegu 41566, South Korea; Univ Nizwa, Nat & Med Sci Res Ctr, Nizwa 616, Oman; Abdul Wali Khan Univ, Dept Bot, Garden Campus, Mardan 23200, Pakistan | Kim, Kyung-Min Kim/C-7007-2014; Asaf, Sajjad/ABA-3647-2021; Khan, Muhammad/ABB-9797-2021; Jan, Rahmatullah/AIC-3439-2022; Lee, In-Jung/GLS-0432-2022 | 57201981969; 57188585606; 56595059900; 57200621537; 16425830900; 34868260300 | rahmat2021@knu.ac.kr;aqil_bacha@knu.ac.kr;sajjadasaf@unizwa.edu.om;lubnabilal68@gmail.com;ijlee@knu.ac.kr;kkm@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 11 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 1.01 | 2025-07-30 | 18 | 19 | lignin; antioxidant; signaling; relative expression; phenylalanine; proline | INDUCED DEFENSE RESPONSES; BROWN PLANTHOPPER; SOGATELLA-FURCIFERA; WHITEBACKED PLANTHOPPER; RESISTANCE; ARABIDOPSIS; GENE; PROTEIN; DROUGHT; CLONING | Antioxidant; Lignin; Phenylalanine; Proline; Relative expression; Signaling | English | 2021 | 2021-11 | 10.3390/antiox10111680 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Paeonia lactiflora Root Extract and Its Components Reduce Biomarkers of Early Atherosclerosis via Anti-Inflammatory and Antioxidant Effects In Vitro and In Vivo | Although various physiological activities of compounds obtained from Paeonia lactiflora have been reported, the effects of P. lactiflora extract (PLE) on early atherosclerosis remain unclear. Therefore, in this study, we investigated the in vitro and in vivo antiatherosclerosis and in vitro antioxidant effects of PLE and its compounds. PLE suppresses the tumor necrosis factor (TNF)-alpha-induced capacity of THP-1 cells to adhere to human umbilical vein endothelial cells (HUVECs), vascular cell adhesion molecule (VCAM)-1 expression, and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappa B) signaling in HUVECs. PLE also suppresses TNF-alpha-induced nuclear translocation of NF-kappa B p65 from cytosol as well as the enhanced TNFA and C-C motif chemokine ligand 2 (CCL2) mRNA expression in HUVECs. We identified and quantified the following PLE compounds using high-performance liquid chromatography with diode array detection: methyl gallate, oxypaeoniflorin, catechin, albiflorin, paeoniflorin, benzoic acid, benzoylpaeoniflorin, and paeonol. Among these, methyl gallate had the strongest inhibitory effect on monocyte adherence to TNF-alpha-induced HUVECs and the VCAM-1 expression. Reverse transcriptase real-time quantitative polymerase chain reaction showed that PLE compounds had a dissimilar inhibition effect on TNF-alpha-induced mRNA expression levels of CCL2, TNFA, and IL6 in HUVECs. Except for paeonol, the compounds inhibited lipopolysaccharide (LPS)-induced reactive oxygen species production in RAW264.7 cells. In vivo, oral administration of PLE improved TNF-alpha-induced macrophage infiltration to the vascular endothelium and expression of VCAM-1, as well as IL6 and TNFA gene expression in the main artery of mice. PLE could be useful as a nutraceutical material against early atherosclerosis via the combined effects of its components. | Kim, Min Jeong; Kang, Hyun-Hee; Seo, Yeung Jin; Kim, Kyung-Min; Kim, Young-Jun; Jung, Sung Keun | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Seoul Natl Univ Sci & Technol, Dept Food Sci & Technol, Seoul 01811, South Korea; Gyeongsangbuk Do Prov Agr Res & Extens Serv, Div Crop Res, Daegu 41404, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu 41566, South Korea | ; Kim, Kyung-Min Kim/C-7007-2014; Kim, Joo/X-7562-2019; Jung, SUNG KEUN/AGR-2623-2022 | 57215818497; 57218542184; 57266828500; 34868260300; 57211016047; 35310491400 | minjung8128@gmail.com;khh266900@seoultech.ac.kr;francisc@korea.kr;kkm@knu.ac.kr;kimyj@seoultech.ac.kr;skjung04@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 10 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 1.55 | 2025-07-30 | 24 | 27 | Paeonia lactiflora; atherosclerosis; monocyte adhesion; vascular inflammation; VCAM-1; NF-kappa B | NF-KAPPA-B; ENDOTHELIAL-CELLS; VASCULAR INFLAMMATION; MONOCYTE ADHESION; CONSTITUENTS; SUPPRESSES; EXPRESSION; INDUCTION; MICE | Atherosclerosis; Monocyte adhesion; NF-κB; Paeonia lactiflora; Vascular inflammation; VCAM-1 | English | 2021 | 2021-10 | 10.3390/antiox10101507 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development | Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have been studied for their antioxidant functions and roles in cancers. However, the physiological significance of Gpx1 and Prdx2 during vertebrate embryogenesis are lacking. Currently, we investigated the functional roles of Gpx1 and Prdx2 during vertebrate embryogenesis using Xenopus laevis as a vertebrate model. Our investigations revealed the zygotic nature of gpx1 having its localization in the eye region of developing embryos, whereas prdx2 exhibited a maternal nature and were localized in embryonic ventral blood islands. Furthermore, the gpx1-morphants exhibited malformed eyes with incompletely detached lenses. However, the depletion of prdx2 has not established its involvement with embryogenesis. A molecular analysis of gpx1-depleted embryos revealed the perturbed expression of a cryba1-lens-specific marker and also exhibited reactive oxygen species (ROS) accumulation in the eye regions of gpx1-morphants. Additionally, transcriptomics analysis of gpx1-knockout embryos demonstrated the involvement of Wnt, cadherin, and integrin signaling pathways in the development of malformed eyes. Conclusively, our findings indicate the association of gpx1 with a complex network of embryonic developmental pathways and ROS responses, but detailed investigation is a prerequisite in order to pinpoint the mechanistic details of these interactions. | Lee, Hongchan; Lee, Na Young; Kim, Youni; Choi, Hong-Seok; Ismail, Tayaba; Ryu, Hong-Yeoul; Cho, Dong-Hyung; Ryoo, Zae Young; Lee, Dong-Seok; Kwon, Taeg Kyu; Park, Tae Joo; Kwon, Taejoon; Lee, Hyun-Shik | Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea; Keimyung Univ, Sch Med, Dept Immunol, Daegu 41566, South Korea; Ulsan Natl Inst Sci & Technol, Coll Informat Bio Convergence, Dept Biol Sci, Ulsan 44919, South Korea; Ulsan Natl Inst Sci & Technol UNIST, Dept Biomed Engn, Coll Informat Bio Convergence, Ulsan 44919, South Korea | ; Park, Tae Joo/G-1460-2011; RYOO, ZAEYOUNG/AAQ-1573-2020; Ismail, Tayaba/LPQ-9181-2024; Kwon, Taejoon/S-3835-2016; Choi, Hye Rin/JDV-9065-2023; Choi, Eun Hwa/HTN-1610-2023 | 57210948333; 57344191000; 57204943696; 57296419700; 57190277495; 55889917800; 35093684400; 16937104900; 57210068061; 7202206057; 58254025900; 35484365800; 16316010200 | leehongchan@hanmail.net;ny0726@knu.ac.kr;poloqq@knu.ac.kr;hschoi9784@knu.ac.kr;tayaba@knu.ac.kr;rhr4757@knu.ac.kr;dhcho@knu.ac.kr;jaewoong64@knu.ac.kr;lee1@knu.ac.kr;kwontk@dsmc.or.kr;parktj@unist.ac.kr;tkwon@unist.ac.kr;leeh@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 10 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 0.08 | 2025-07-30 | 1 | 1 | Gpx1; Prdx2; embryogenesis; eye development; lens detachment; morpholinos; VBI | OXIDATIVE STRESS; PEROXIREDOXIN-II; EXPRESSION; CANCER; PROMOTES; RISK | Embryogenesis; Eye development; Gpx1; Lens detachment; Morpholinos; Prdx2; VBI | English | 2021 | 2021-10 | 10.3390/antiox10101636 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Phytohormones Producing Acinetobacter bouvetii P1 Mitigates Chromate Stress in Sunflower by Provoking Host Antioxidant Response | Different physical and chemical techniques are used for the decontamination of Cr+6 contaminated sites. The techniques are expensive, laborious, and time-consuming. However, remediation of Cr+6 by microbes is viable, efficient, and cost-effective. In this context, plant growth-promoting rhizobacteria Acinetobacter bouvetii P1 isolated from the industrial zone was tested for its role in relieving Cr+6 induced oxidative stress in sunflower. At the elevated Cr+6 levels and in the absence of P1, the growth of the sunflower plants was inhibited. In contrast, the selected strain P1 restored the sunflower growth under Cr+6 through plant growth-promoting interactions. Specifically, P1 biotransformed the Cr+6 into a stable and less toxic Cr+3 form, thus avoiding the possibility of phytotoxicity. On the one hand, the P1 strengthened the host antioxidant system by triggering higher production of enzymatic antioxidants, including catalases, ascorbate peroxidase, superoxide dismutase, and peroxidase. Similarly, P1 also promoted higher production of nonenzymatic antioxidants, such as flavonoids, phenolics, proline, and glutathione. Apart from the bioremediation, P1 solubilized phosphate and produced indole acetic acid, gibberellic acid, and salicylic acid. The production of phytohormones not only helped the host plant growth but also mitigated the harsh condition posed by the elevated levels of Cr+6. The findings mentioned above suggest that P1 may serve as an excellent phyto-stimulant and bio-remediator in a heavy metal-contaminated environment. | Qadir, Muhammad; Hussain, Anwar; Hamayun, Muhammad; Shah, Mohib; Iqbal, Amjad; Irshad, Muhammad; Ahmad, Ayaz; Lodhi, Muhammad Arif; Lee, In-Jung | Abdul Wali Khan Univ Mardan, Dept Bot, Garden Campus, Mardan 23200, Pakistan; Abdul Wali Khan Univ Mardan, Dept Food Sci & Technol, Garden Campus, Mardan 23200, Pakistan; Abdul Wali Khan Univ Mardan, Dept Biotechnol, Garden Campus, Mardan 23200, Pakistan; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea | Ayaz, Ahmad/GVT-1025-2022; Hussain, Anwar/N-1605-2019; Lee, In-Jung/GLS-0432-2022; Lodhi, Muhammad/I-8039-2015; Irshad, Muhammad/JQW-6402-2023; Shah, Mohib/AEK-5703-2022; Hamayun, Muhammad/B-1694-2010; Iqbal, Amjad/E-2010-2014; Qadir, Muhammad/AFJ-3919-2022; Ahmad, Ayaz/GVT-1025-2022 | 22980624600; 35621772200; 59297330100; 56433799400; 10142205100; 57206301341; 55420263200; 7003444928; 16425830900 | muhammad_qadir@awkum.edu.pk;drhussain@awkum.edu.pk;hamayun@awkum.edu.pk;mohibshah@awkum.edu.pk;amjadiqbal@awkum.edu.pk;muhammad.irshad@awkum.edu.pk;arif.lodhi@awkum.edu.pk;ijlee@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 12 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 2.17 | 2025-07-30 | 24 | 31 | Cr+6 bioremediation; improved antioxidant activity; plant growth promotion; rhizobacteria | GROWTH-PROMOTING TRAITS; HEAVY-METAL; GLUTATHIONE-REDUCTASE; CHROMIUM; PLANTS; WATER; TOXICITY; RHIZOBACTERIA; PURIFICATION; RHIZOSPHERE | Cr<sup>+6</sup> bioremediation; Improved antioxidant activity; Plant growth promotion; Rhizobacteria | English | 2021 | 2021-12 | 10.3390/antiox10121868 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Protective Effect of Pyrus ussuriensis Maxim. Extract against Ethanol-Induced Gastritis in Rats | Pyrus ussuriensis Maxim (Korean pear) has been used for hundreds of years as a traditional herbal medicine for asthma, cough, and atopic dermatitis in Korea and China. Although it was originally shown to possess anti-inflammatory, antioxidant, and antiatopic properties, its gastroprotective effects have not been investigated. In the present study, we evaluated the protective effects of Pyrus ussuriensis Maxim extract (PUE) against ethanol-induced gastritis in rats. The bioactive compound profile of PUE was determined by gas chromatography mass spectroscopy (GC-MS) and high-performance liquid chromatography (HPLC). The gastroprotection of PUE at different doses (250 and 500 mg/kg body weight) prior to ethanol ingestion was evaluated using an in vivo gastritis rat model. Several endpoints were evaluated, including gastric mucosal lesions, cellular degeneration, intracellular damage, and immunohistochemical localization of leucocyte common antigen. The gastric mucosal injury and ulcer score were determined by evaluating the inflamed gastric mucosa and by histological examination. To identify the mechanisms of gastroprotection by PUE, antisecretory action and plasma prostaglandin E-2 (PGE(2)), gastric mucosal cyclic adenosine monophosphate (cAMP), and histamine levels were measured. PUE exhibited significant antioxidant effects with IC50 values of 56.18 and 22.49 mu g/mL for 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2 '- azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) inhibition (%), respectively. In addition, GC/MS and HPLC analyses revealed several bioactive compounds of PUE. Pretreatment with PUE significantly (p < 0.05) decreased the ulcer index by preventing gastric mucosal lesions, erosion, and cellular degeneration. An immunohistochemical analysis revealed that PUE markedly attenuated leucocyte infiltration in a dose-dependent manner. The enhancement of PGE(2) levels and attenuation of cAMP levels along with the inhibition of histamine release following PUE pretreatment was associated with the cytoprotective and healing effects of PUE. In contrast, the downregulation of the H+/K+ ATPase pathway as well as muscarinic receptor (M3R) and histamine receptor (H2R) inhibition was also involved in the gastroprotective effects of PUE; however, the expression of cholecystokinin-2 receptors (CCK2R) was unchanged. Finally, no signs of toxicity were observed following PUE treatment. Based on our results, we conclude that PUE represents an effective therapeutic option to reduce the risk of gastritis and warrants further study. | Boby, Naila; Abbas, Muhammad Aleem; Lee, Eon-Bee; Im, Zi-Eum; Hsu, Walter H.; Park, Seung-Chun | Kyungpook Natl Univ, Coll Vet Med, Lab Vet Pharmacokinet & Pharmacodynam, Daegu 41566, South Korea; Inst Forest Resources Dev, Andong 36605, Gyeongsangbuk D, South Korea; Iowa State Univ, Coll Vet Med, Dept Biomed Sci, Ames, IA 50011 USA | Park, Seung-Chun/AAV-3388-2021; Abbas, Muhammad Aleem/GLT-8362-2022; Lee, Jung Bok/HHZ-3200-2022; Boby, Naila/GRE-8096-2022 | 57197787296; 57216531374; 57216526135; 57205463137; 7402002883; 7501832396 | nailaboby@knu.ac.kr;syedaleemabbas77@knu.ac.kr;eonbee@knu.ac.kr;zium78@korea.kr;whsu@iastate.edu;parksch@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 3 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 1.24 | 2025-07-30 | 18 | 20 | Pyrus ussuriensis Maxim; GC-MS; HPLC analysis; antioxidant; IC50; gastritis; ulcer scoring; leucocytes common antigen; prostaglandin E-2; H+; K+ ATPase | NF-KAPPA-B; CHLOROGENIC ACID; ANTIOXIDANT PROPERTIES; CHEMICAL-COMPOSITION; PHENOLIC-COMPOUNDS; SPONDIAS-MOMBIN; MUCOSAL DEFENSE; INHIBITION; ULCER; PEAR | Antioxidant; Gastritis; GC‐MS; H<sup>+</sup>/K<sup>+</sup> ATPase; HPLC analysis; IC50; Leucocytes common antigen; Prostaglandin E2; Pyrus ussuriensis Maxim; Ulcer scoring | English | 2021 | 2021-03 | 10.3390/antiox10030439 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Recent Molecular Mechanisms and Beneficial Effects of Phytochemicals and Plant-Based Whole Foods in Reducing LDL-C and Preventing Cardiovascular Disease | Abnormal lipid metabolism leads to the development of hyperlipidemia, a common cause of multiple chronic disorders, including cardiovascular disease (CVD), obesity, diabetes, and cerebrovascular disease. Low-density lipoprotein cholesterol (LDL-C) currently remains the primary target for treatment of hyperlipidemia. Despite the advancement of treatment and prevention of hyperlipidemia, medications used to manage hyperlipidemia are limited to allopathic drugs, which present certain limitations and adverse effects. Increasing evidence indicates that utilization of phytochemicals and plant-based whole foods is an alternative and promising strategy to prevent hyperlipidemia and CVD. The current review focuses on phytochemicals and their pharmacological mode of actions for the regulation of LDL-C and prevention of CVD. The important molecular mechanisms illustrated in detail in this review include elevation of reverse cholesterol transport, inhibition of intestinal cholesterol absorption, acceleration of cholesterol excretion in the liver, and reduction of cholesterol synthesis. Moreover, the beneficial effects of plant-based whole foods, such as fresh fruits, vegetables, dried nuts, flax seeds, whole grains, peas, beans, vegan diets, and dietary fibers in LDL-C reduction and cardiovascular health are summarized. This review concludes that phytochemicals and plant-based whole foods can reduce LDL-C levels and lower the risk for CVD. | Islam, Salman Ul; Ahmed, Muhammad Bilal; Ahsan, Haseeb; Lee, Young-Sup | Kyungpook Natl Univ, BK21 4 KNU Creat BioRes Grp, Sch Life Sci, Daegu 41566, South Korea; Univ Peshawar, Fac Life & Environm Sci, Dept Pharm, Peshawar 25120, Pakistan | ; Ahsan, Haseeb/Y-2866-2018 | 56985186700; 58689879600; 57531232400; 36013628200 | salman2013@knu.ac.kr;muhammad786@knu.ac.kr;haseeb2020@knu.ac.kr;yselee@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 5 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 2 | 2025-07-30 | 58 | 73 | plant-based foods; LDL; CVD; lipid oxidation; dietary fiber; cholesterol; hyperlipidemia | CORONARY-HEART-DISEASE; GENE-EXPRESSION; NUT CONSUMPTION; CHOLESTEROL; RISK; METAANALYSIS; TRIGLYCERIDES; SECRETION; PROTEIN; FIBER | Cholesterol; CVD; Dietary fiber; Hyperlipidemia; LDL; Lipid oxidation; Plant-based foods | English | 2021 | 2021-05 | 10.3390/antiox10050784 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Siegesbeckiae Herba Extract and Chlorogenic Acid Ameliorate the Death of HaCaT Keratinocytes Exposed to Airborne Particulate Matter by Mitigating Oxidative Stress | Airborne particulate matter with a size of 10 mu m or less (PM10) can cause oxidative damages and inflammatory reactions in the skin. This study was conducted to discover natural products that are potentially useful in protecting the skin from PM10. Among the hot water extracts of a total of 23 medicinal plants, Siegesbeckiae Herba extract (SHE), which showed the strongest protective effect against PM10 cytotoxicity, was selected, and its mechanism of action and active constituents were explored. SHE ameliorated PM10-induced cell death, lactate dehydrogenase (LDH) release, lipid peroxidation, and reactive oxygen species (ROS) production in HaCaT cells. SHE decreased the expression of KEAP1, a negative regulator of NRF2, and increased the expression of NRF2 target genes, such as HMOX1 and NQO1. SHE selectively induced the enzymes involved in the synthesis of GSH (GCL-c and GCL-m), the regeneration of GSH (GSR and G6PDH), and GSH conjugation of xenobiotics (GST kappa 1), rather than the enzymes that directly scavenge ROS (SOD1, CAT, and GPX1). SHE increased the cellular content of GSH and mitigated the oxidation of GSH to GSSG caused by PM10 exposure. Of the solvent fractions of SHE, the n-butyl alcohol (BA) fraction ameliorated cell death in both the absence and presence of PM10. The BA fraction contained a high amount of chlorogenic acid. Chlorogenic acid reduced PM10-induced cell death, LDH release, and ROS production. This study suggests that SHE protects cells from PM10 toxicity by increasing the cellular antioxidant capacity and that chlorogenic acid may be an active phytochemical of SHE. | Ha, Jae Won; Boo, Yong Chool | Kyungpook Natl Univ, Cell & Matrix Res Inst, BK21 Plus KNU Biomed Convergence Program, Dept Mol Med,Sch Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea | 57210154932; 6602899130 | jaewon1226@knu.ac.kr;ycboo@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 11 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 1.71 | 2025-07-30 | 28 | 28 | Siegesbeckiae Herba; Siegesbeckia pubescens Makino; airborne particulate matter; PM10; glutamate-cysteine ligase; nuclear factor erythroid 2-related factor 2; glutathione; chlorogenic acid; caffeic acid | CELL VIABILITY; EXPRESSION; SURVIVAL; MTT; ANTIOXIDANTS; GLUTATHIONE; POLLUTANTS; PARTICLES; RESPONSES; PATHWAY | Airborne particulate matter; Caffeic acid; Chlorogenic acid; Glutamate-cysteine ligase; Glutathione; Nuclear factor erythroid 2-related factor 2; PM<sub>10</sub>; Siegesbeckia pubescens makino; Siegesbeckiae herba | English | 2021 | 2021-11 | 10.3390/antiox10111762 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | The Quantitative Trait Loci Mapping of Rice Plant and the Components of Its Extract Confirmed the Anti-Inflammatory and Platelet Aggregation Effects In Vitro and In Vivo | Unpredictable climate change might cause serious lack of food in the world. Therefore, in the present world, it is urgent to prepare countermeasures to solve problems in terms of human survival. In this research, quantitative trait loci (QTLs) were analyzed when rice attacked by white backed planthopper (WBPH) were analyzed using 120 Cheongcheong/Nagdong double haploid lines. Moreover, from the detected QTLs, WBPH resistance-related genes were screened in large candidate genes. Among them, OsCM, a major gene in the synthesis of Cochlioquinone-9 (cq-9), was screened. OsCM has high homology with the sequence of chorismate mutase, and exists in various functional and structural forms in plants that produce aromatic amino acids. It also induces resistance to biotic stress through the synthesis of secondary metabolites in plants. The WBPH resistance was improved in rice overexpressed through map-based cloning of the WBPH resistance-related gene OsCM, which was finally detected by QTL mapping. In addition, cq-9 increased the survival rate of caecal ligation puncture (CLP)-surgery mice by 60%. Moreover, the aorta of rat treated with cq-9 was effective in vasodilation response and significantly reduced the aggregation of rat platelets induced by collagen treatment. A cq-9, which is strongly associated with resistance to WBPH in rice, is also associated with positive effect of CLP surgery mice survival rate, vasodilation, and significantly reduced rat platelet aggregation induced by collagen treatment. Therefore, cq-9 presents research possibilities as a substance in a new paradigm that can act on both Plant-Insect in response to the present unpredictable future. | Park, Jae-Ryoung; Jan, Rahmatullah; Park, Seul-Gi; Handoyo, Tri; Lee, Gang-Seob; Yun, Sopheap; Jang, Yoon-Hee; Du, Xiao-Xuan; Lee, Taeho; Kwon, Yong-Sham; Kim, Doh Hoon; Seok, Young-Mi; Bae, Jong-Sup; Kim, Kyung-Min | Kyungpook Natl Univ, Sch Appl Biosci, Div Plant Biosci, Coll Agr & Life Sci, 80 Dahak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Costal Agr Res Inst, 80 Dahak Ro, Daegu 41566, South Korea; Natl Inst Crop Sci, Rural Dev Adm, Jeonju 54874, South Korea; Jember Univ, Dept Agron, Fac Agr, Jl Kalimantan 37, Jember 68121, Indonesia; Natl Acad Agr Sci, Biosafety Div, Rural Dev Adm, Jeonju 54874, South Korea; Royal Univ Phnom Penh, Grad Sch Sci, Sangkat Teuk Laak 1,Russian Federat Blvd, Toul Kork 12101, Phnom Penh, Cambodia; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Coll Pharm, 80 Dahak Ro, Daegu 41566, South Korea; Dong A Univ, Dept Genet Engn, Coll Nat Resources & Life Sci, Busan 49315, South Korea; Natl Inst Korean Med Dev, Dept Korean Med Dev, 94 Hwarang Ro, Gyongsan 38540, Gyeongsangbuk D, South Korea | Kim, Kyung-Min Kim/C-7007-2014; Du, Xiaoxuan/AGZ-8638-2022; Bae, Jong-Sup/AAU-9724-2020; Jan, Rahmatullah/AIC-3439-2022; Handoyo, Tri/AGX-6311-2022 | 57211205505; 57201981969; 57212010761; 12775151000; 25927158200; 57190670675; 57219901992; 57209098077; 57204032003; 57211722852; 7409766359; 16069799100; 16021543200; 34868260300 | icd92@knu.ac.kr;rahmat2021@knu.ac.kr;ahsia1004@korea.com;trihandoyo.faperta@unej.ac;kangslee@korea.kr;yun.sopheap@rupp.edu.kr;uni@knu.ac.kr;duxiaoxuan@korea.kr;tlee@knu.ac.kr;kkmkim@hanmail.net;imaria@nikom.or.kr;baejs@knu.ac.kr;kkm@knu.ac.kr; | ANTIOXIDANTS | ANTIOXIDANTS-BASEL | 2076-3921 | 10 | 11 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY | 2021 | 7.675 | 5.6 | 0.15 | 2025-07-30 | 3 | 2 | cochlioquinone; defense; platelet aggregation; QTL; rice | SECONDARY METABOLITES; EPI-COCHLIOQUINONES; GENE DISRUPTION; QTL ANALYSIS; BIOSYNTHESIS; TRANSFORMATION; PURIFICATION; ACTIVATION; EXPRESSION; SYNTHASE | Cochlioquinone; Defense; Platelet aggregation; QTL; Rice | English | 2021 | 2021-11 | 10.3390/antiox10111691 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A novel blue-emitting phosphors (CsBaYB6O12:Ce³⁺): Potential applications in w-LEDs and X-ray phosphors | We have synthesized powder samples of pure and Ce3+ doped cesium barium yttrium hexaborate (CsBaYB6O12) using a standard solid-state reaction technique. The prepared samples were characterized by different techniques. Powder X-ray diffraction (PXRD) was used to identify the phase purity of the prepared phosphors. The field emission scanning electron microscopy (FE-SEM) technique was used to examine the size and shape of the synthesized powder samples. The energy-dispersive spectral analysis (EDS) was used to identify the elements present in the synthesized compounds. X-ray-induced luminescence spectra, photoluminescence (PL), and thermoluminescence (TL) analysis were used to investigate the luminescence properties of the prepared compound. The rare earth ion of Ce3+ improves the intrinsic luminescence of CsBaYB6O12 and 4 mol% was found to be the optimal concentration. The dopants found to have two different excitation PL bands at 340 nm and 360 nm which yields the same emission bands of 385 and 417 nm which are well-matched with that found in the X-ray emission bands. The kinetic parameters of the measured experimental TL glow curve has been studied by various standard methods such as deconvolution, Variable heating rate and initial rise method. In this manuscript we report the luminescence properties of the prepared phosphors in a detailed manner for the first time. (C) 2021 Elsevier B.V. All rights reserved. | Ntarisa, Amos Vincent; Daniel, D. Joseph; Balaji, D.; Raja, Arumugam; Kim, H. J.; Quang, Nguyen Duy | Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Sri Vidya Mandir Arts & Sci Coll, Dept Phys, Uthangarai 636902, Tamil Nadu, India; Sri Sivasubramaniya Nadar Coll Engn, SSN Res Ctr, Kalavakkam 603110, Tamil Nadu, India | Raja, Arumugam/Q-1781-2019; Ntarisa, Amos/JWO-6086-2024; Ntarisa, Amos Vincent/JWO-6086-2024; Kim, Hong Joo/AAE-1178-2022 | 57160289700; 35319662800; 57195567330; 57189505213; 59051568100; 57223004024 | hongjoo@knu.ac.kr; | JOURNAL OF ALLOYS AND COMPOUNDS | J ALLOY COMPD | 0925-8388 | 1873-4669 | 873 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING | 2021 | 6.371 | 5.7 | 1.34 | 2025-07-30 | 21 | 23 | Borate; Phosphors; Solid-state reaction; Luminescence | ENERGY-TRANSFER; OPTICAL-PROPERTIES; PHOTOLUMINESCENCE; LUMINESCENCE; PARAMETERS; EMISSION; SERIES; CE3+ | A. Borate; B. Phosphors; C. Solid-state reaction; D. Luminescence | Barium compounds; Cerium compounds; Emission spectroscopy; Enamels; Field emission microscopes; Light emitting diodes; Luminescence of inorganic solids; Metal ions; Phosphors; Rare earths; Scanning electron microscopy; Spectrum analysis; Thermoluminescence; Yttrium compounds; A borate; B phosphor; Blue-emitting phosphor; C solid-state reaction; Ce$+3+$; D luminescence; Emission bands; Luminescence properties; Powder samples; Synthesized powder; Solid state reactions | English | 2021 | 2021-08-25 | 10.1016/j.jallcom.2021.159676 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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