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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Review | Advances in Preventive and Therapeutic Strategies for Oral Cancer: A Short Review | Oral cancer is a major global health concern, with high incidence and mortality rates, especially in high-risk populations. Early diagnosis remains a challenge, and current treatments, such as surgery, radiation, and chemotherapy, have limited effectiveness, particularly in advanced stages. Recent advances in targeted therapies and immunotherapy offer promising alternatives, providing more precise and personalized treatment options. Targeted therapies, such as epidermal growth factor receptor inhibitors, aim to disrupt specific molecular pathways in tumor growth, while immunotherapies, including immune checkpoint inhibitors and chimeric antigen receptor-T cell therapy, enhance the body's immune response to fight cancer. Combination therapies, integrating both targeted and immune strategies, are being explored to overcome the limitations of single-agent treatments. This review highlights the current strategies in the prevention and treatment of oral cancer, discusses emerging therapies, explores future research directions, focusing on optimizing existing treatments, identifying new biomarkers, and developing innovative therapeutic approaches. The potential of personalized medicine and combination therapies offers new hope for improving survival rates and quality of life for oral cancer patients. | Ma, Lei; Kim, Myoung Ok | Kyungpook Natl Univ, Res Inst Innovat Anim Sci, Dept Anim Sci & Biotechnol, Sangju, South Korea | ok4325@knu.ac.kr; | JOURNAL OF CANCER PREVENTION | J CANCER PREV | 2288-3649 | 2288-3657 | 29 | 4 | ESCI | ONCOLOGY | 2024 | 1.8 | 77.1 | 0 | Oral cancer; Targeted therapy; Immunotherapy; Combination therapy; Prevention | RADIATION-THERAPY; IMMUNOTHERAPY; CETUXIMAB; HEAD | English | 2024 | 2024-12-30 | 10.15430/jcp.24.027 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | Review | Evolving Therapeutic Strategies in Esophageal Squamous Cell Carcinoma: Advances and Perspectives | Esophageal squamous cell carcinoma (ESCC) is among the most prevalent forms of esophageal cancer globally, with a particularly high incidence in developing countries. Notably, Asia accounts for approximately 80% of global esophageal cancer cases, with China alone contributing to 54% of this burden. The primary treatment modality for ESCC remains esophagectomy, primarily employed for locally advanced disease, often in combination with chemotherapy and radiotherapy for advanced-stage cases. Despite significant advancements in surgical techniques and the advent of precision medicine, which has facilitated the development of targeted and immune-based therapies, critical challenges persist, including suboptimal therapeutic efficacy and the emergence of drug resistance. A comprehensive understanding of the current treatment landscape for ESCC is essential to overcoming these barriers and improving patient outcomes. | Liu, Zhibin; Kim, Myoung Ok | Kyungpook Natl Univ, Res Inst Innovat Anim Sci, Dept Anim Sci & Biotechnol, Sangju, South Korea | ok4325@knu.ac.kr; | JOURNAL OF CANCER PREVENTION | J CANCER PREV | 2288-3649 | 2288-3657 | 29 | 4 | ESCI | ONCOLOGY | 2024 | 1.8 | 77.1 | 0 | Esophageal squamous cell carcinoma; General Surgery; Chemotherapy; Radiotherapy | INTENSITY-MODULATED RADIOTHERAPY; LYMPH-NODE DISSECTION; SURGICAL-TREATMENT; RADIATION-THERAPY; PREOPERATIVE CHEMORADIOTHERAPY; PROTON THERAPY; CANCER; RESECTION; ADENOCARCINOMA; OUTCOMES | English | 2024 | 2024-12-30 | 10.15430/jcp.24.026 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | INDOLE ACETIC ACID AND GIBBERELLIC ACID ENHANCE PHYSIOLOGICAL AND BIOCHEMICAL PERFORMANCE OF JATROPHA CURCAS L. UNDER WATERLOGGING AND DROUGHT STRESS | Jatropha curcas L. ( J. curcas ) is an emerging biodiesel plant attracting the interest of researcher around the globe. The current study was performed to enhance the growth of J. curcas under water logged and drought stress condition through application of phytohormones. We treated the plants with 100 mM and 250 mM Indole acetic acid (IAA) and Gibberellic acid (GA) exogenously. The study was performed in pots in summer and winter separately. The results showed that, all the plants died in the winter due to frost condition which showed that J. curcas was highly susceptible to low temperature and frost condition. Further experiment was carried out on the plants grown in summer. Both the hormones increased the plant height under both the stresses while the length of root was considerably increased by GA in the water logged and drought stress conditions compared to IAA. The root and shoot fresh and dry weight were enhanced significantly by GA 250 mM.. Leaves and branches number, and stem diameter were greatly affected by water logging and drought stress, however both the hormonal application increased these parameters. Further the results showed that, GA 250 mM highly increased the proximate compositions in both the stresses followed by IAA 250 mM. These results collectively demonstrate that the external administration of IAA and GA stimulates the growth and development of J. curcas under conditions of waterlogging and drought stress by modulating various morphological, physiological, and biochemical parameters. | Jan, Rahmatullah; Adnan, Muhammad; Hashem, Abeer; Abd Allah, Elsayed Fathi; Murad, Waheed; Kim, Kyung-Min | Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Kyungpook Natl Univ, Coastal Agr Res Inst, Daegu 41566, South Korea; Kohat Univ Sci & Technol, Dept Bot, Kohat 26000, Khyber Pakhtunk, Pakistan; King Saud Univ, Coll Sci, Bot & Microbiol Dept, POB 2460, Riyadh 11451, Saudi Arabia; King Saud Univ, Coll Food & Agr Sci, Plant Protect Dept, POB 2460, Riyadh 11451, Saudi Arabia; Abdul Wali Khan Univ, Dept Bot, Mardan 23200, Pakistan | Jan, Rahmatullah/LFU-1421-2024; Murad, Waheed/HGE-7090-2022; Abd_Allah, Elsayed Fathi/N-6846-2017; Adnan, Muhammad/AGI-4537-2022; Abd_Allah, Elsayed/N-6846-2017; Kim, Kyung-Min Kim/C-7007-2014; Hashem, Abeer/AAX-5952-2021 | 57201981969; 57214352598; 12800807100; 6603162841; 55394220500; 34868260300 | waheedmurad@awkum.edu.pk;kkm@knu.ac.kr; | PAKISTAN JOURNAL OF BOTANY | PAK J BOT | 0556-3321 | 2070-3368 | 56 | 5 | SCIE | PLANT SCIENCES | 2024 | 0.9 | 77.1 | 0 | 2025-05-07 | 1 | 1 | Drought; Gibberellic acid; Indole acetic acid; Jatropha curcas; Waterlogging | WATER-STRESS; CHLOROPHYLL FLUORESCENCE; GROWTH-RESPONSES; GAS-EXCHANGE; PLANT-GROWTH; SEEDLINGS; YIELD; AUXIN; PHOTOSYNTHESIS; ACCLIMATION | Drought; Gibberellic acid; Indole acetic acid; Jatropha curcas; Waterlogging | English | 2024 | 2024-10 | 10.30848/pjb2024-5(13) | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Lipid metabolism pathway genes and lung cancer: ACADSB rs12220683G>C is associated with better survival outcome in patients with non-small cell lung cancer | Altered lipid metabolism has been reported to be associated with prognosis in multiple cancers. This study aimed to investigate the association of polymorphisms in lipid metabolism pathway genes with survival outcomes in patients with surgically resected non-small cell lung cancer (NSCLC). In total, 744 patients with surgically resected NSCLC (380 in the discovery cohort and 364 in the validation cohort) were included in this study. Among the 176 investigated polymorphisms, ACADSB rs10902859G>A was associated with significantly better overall survival (OS) in the discovery, validation, and combined cohorts. ACADSB rs10902859G>A was located in the repressed region and had strong linkage disequilibrium (D & PRIME; = 1.00 and r2 = 0.94), with rs12220683G>C located in the H3K4me3 peak region, which indicates the presence of active promoters. ACADSB rs12220683G>C was also associated with better OS in the discovery, validation, and combined cohorts (in a dominant model; adjusted hazard ratio [aHR] = 0.53, 95% confidence interval [CI] = 0.30-0.94, P = 0.03; aHR = 0.37, 95% CI = 0.15-0.89, P = 0.03; and aHR = 0.47, 95% CI = 0.29-0.75, P = 0.002, respectively). In vitro luciferase assay demonstrated that the promoter activity of ACADSB was significantly increased in the rs12220683 variant C allele compared with that in the wild G allele (P = 3 x 10-5). These results suggest that ACADSB rs12220683G>C increases promoter activity and that increased ACADSB expression may result in better OS in patients with surgically resected NSCLC. | Yoo, Seung Soo; Do, Sook Kyung; Choi, Jin Eun; Kang, Hyo-Gyoung; Hong, Mi Jeong; Lee, Jang Hyuck; Lee, Won Kee; Do, Young Woo; Lee, Eung Bae; Park, Ji Eun; Choi, Sun Ha; Seo, Hyewon; Lee, Yong Hoon; Lee, Jaehee; Lee, Shin Yup; Cha, Seung Ick; Kim, Chang Ho; Park, Jae Yong | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biochem & Cell Biol, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Med Res Collaborat Ctr, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Thorac Surg, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, Daegu 680 gukchaeb, South Korea | Lee, Yoojin/AAB-9799-2022; JY, LEE/GRS-9767-2022; Lee, Jaehee/S-1697-2018 | 56479781600; 56333658000; 37107028100; 8573181300; 55613917100; 57161223200; 22953484700; 57189600352; 55664096100; 57195437358; 57199723585; 55612130200; 57199022948; 13805476000; 49863712700; 35227126400; 7409873555; 58360293800 | wkiki0928@naver.com;jaeyong@knu.ac.kr; | ONCOLOGY | ONCOLOGY-BASEL | 0030-2414 | 1423-0232 | 102 | 1 | SCIE | ONCOLOGY | 2024 | 1.8 | 77.1 | 0 | 2025-04-16 | 0 | 0 | FATTY-ACID-METABOLISM | Lipid metabolism; Non-small cell lung cancer; Polymorphism; Surgery; Survival | Carcinoma, Non-Small-Cell Lung; Genotype; Humans; Lipid Metabolism; Lung Neoplasms; Polymorphism, Single Nucleotide; Prognosis; histone H3; messenger RNA; acyl CoA dehydrogenase short branched chain gene; aged; Article; cancer patient; cancer surgery; cancer survival; clinical outcome; cohort analysis; controlled study; female; gender; gene linkage disequilibrium; genetic association; genetic variability; hazard ratio; histopathology; human; in vitro study; lipid metabolism; luciferase assay; major clinical study; male; mRNA expression level; non small cell lung cancer; observational study; overall survival; promoter region; retrospective study; single nucleotide polymorphism; smoking; survival rate; survival time; tumor gene; validation study; genetics; genotype; lipid metabolism; lung tumor; metabolism; prognosis; single nucleotide polymorphism | English | 2024 | 2024-01 | 10.1159/000533156 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | PHYSIOLOGICAL AND MOLECULAR ADAPTATION RESPONSE OF SOYBEAN SEEDLINGS UNDER OSMOTIC STRESS | Water is essential for plant growth and development; however, an excessive and lower amount of water negatively affects crop productivity and survival. In natural ecosystems, flash floods may cause the complete submergence of plants in water, which results in the induction of multiple stress tolerance mechanisms. The conditions underwater and the reaction of plants to these conditions are low oxygen, low light, and nutrient deficiency come under the former category of drought stress and are conditions that the plant faces underwater. Production of endogenous hormones and activation of signaling molecules of the glutamate family are the plant responses to the above stress conditions. A high risk of infection is a consequence of being immersed in water. In this study, we aimed to explore soybean's tolerance mechanisms and acclimatization responses to partial and complete submergence and drought at the physiological and molecular levels, which will provide insights into the regulatory networks eliciting tolerance during water stress. The results suggested that upon exposure to the osmotic stress, there is an increase in the concentration of histidine, arginine, proline, and glutamate contents in the complete submergence and drought stress group as compared to the control group. Moreover, the results also suggested that the SA level increases in its 12 hours and then decreases in the next 120 hours. Interestingly the regulation of ABA is the opposite. It increases as it increases with time. An increased width leaf was observed in all study groups except the control group. | Kang, Sang Mo; Shaffique, Shifa; Peter, Odongkara; Injamum-Ul-Hoqueand, Md; Lee, In-Jung | Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea | Kang, Sang-Mo/MBG-7823-2025; shaffique, shifa/KUC-7102-2024; Lee, In-Jung/GLS-0432-2022 | 56189696900; 57203898867; 58663785500; 58663974700; 16425830900 | ijlee@knu.ac.kr; | PAKISTAN JOURNAL OF BOTANY | PAK J BOT | 0556-3321 | 2070-3368 | 56 | 3 | SCIE | PLANT SCIENCES | 2024 | 0.9 | 77.1 | 1.34 | 2025-04-16 | 2 | 3 | Physio-molecular; ROS; Soybean; Water stress | WATER-STRESS; SHOOT ELONGATION; PHOTOSYNTHESIS; DROUGHT; PLANTS; TOLERANCE; GROWTH | Physio-molecular; ROS; Soybean; Water stress | English | 2024 | 2024-06 | 10.30848/pjb2024-3(34) | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Analysis of dietary behavior and intake related to glycemic control in patients with type 2 diabetes aged 30 years or older in Korea: Utilizing the 8th Korea National Health and Nutrition Examination Survey (2019-2021) | BACKGROUND/OBJECTIVES: Over the past 10 yrs, the prevalence of diabetes in Korea has continued to incline, and the importance of lifestyle modification to manage diabetes has been highlighted. For patients with diabetes, carbohydrate intake reduction is effective in improving glycemic control; thus, we aimed to analyze the effect of carbohydrate intake ratio and suggest an appropriate carbohydrate intake ratio. SUBJECTS/METHODS: Using the 8th Korea National Health and Nutrition Examination Survey (2019-2021), we analyzed the data including participants aged 30 yrs or older with diabetes, and they were stratified into good and poor glycemic control groups. To analyze the correlation between the dietary behavior characteristics of participants with diabetes and the carbohydrate intake ratio, sociodemographic characteristics, dietary behavior, and health behavior were adjusted, and multivariate logistic regression analysis was conducted to present the adjusted odds ratio and 95% confidence interval (CI). RESULTS: In the unadjusted crude model, when carbohydrate intake ratio in total energy intake increased by 1%, the likelihood of poor glycemic control increased by 1.007 -fold (95% CI, 0.998-1.016; P = 0.121). In model 1, which uses age and sex as adjustment variables, an increase of up to 1.011 -fold was possible (95% CI, 1.001-1.021; P = 0.008). In model 2, which added variables such as diabetes duration, frequency of fruit consumption, frequency of lunch and, frequency of dinner, the risk of poor glycemic control increased by 1.010 -fold as the carbohydrate intake ratio increased (95% CI, 0.998-1.022; P < 0.001). CONCLUSION: This study confirmed that as the ratio of carbohydrate intake to total energy intake increases the likelihood of poor glycemic control also increases in patients with diabetes. Therefore, to improve glycemic control in patients with diabetes, controlling the carbohydrate intake may be helpful. | Seok, Jin-Ah; Lee, Yeon-Kyung | Kyungpook Natl Univ, Dept Food Sci & Nutr, 80 Daehak Ro, Daegu 41566, South Korea | Lee, Yeon-Kyung/AAA-1916-2020 | 58994965100; 16301462200 | yklee@knu.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 18 | 2 | SCIE | NUTRITION & DIETETICS | 2024 | 1.5 | 77.2 | 0 | 2025-05-07 | 1 | 0 | Diabetes mellitus; glycemic control; carbohydrate; nutrition surveys; feeding behavior | CONSENSUS REPORT; MANAGEMENT; ADULTS; ASSOCIATIONS | carbohydrate; Diabetes mellitus; feeding behavior; glycemic control; nutrition surveys | English | 2024 | 2024-04 | 10.4162/nrp.2024.18.2.239 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Editorial Material | Analysis of dietary behavior and intake related to glycemic control in patients with type 2 diabetes aged 30 years or older in Korea: Utilizing the 8th Korea National Health and Nutrition Examination Survey (2019-2021) (vol 18, pg 239, 2024) | Seok, Jin-Ah; Lee, Yeon-Kyung | Kyungpook Natl Univ, Dept Food Sci & Nutr, Daegu 41566, South Korea | Lee, Yeon-Kyung/AAA-1916-2020 | 58994965100; 16301462200 | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 18 | 3 | SCIE | NUTRITION & DIETETICS | 2024 | 1.5 | 77.2 | 0 | 2025-05-07 | 0 | 0 | adult; aged; erratum; female; glycemic control; human; Korea; male; non insulin dependent diabetes mellitus; nutrition; public health | English | 2024 | 2024-06 | 10.4162/nrp.2024.18.3.446 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Animal protein hydrolysate reduces visceral fat and inhibits insulin resistance and hepatic steatosis in aged mice | BACKGROUND/OBJECTIVES: An increasing life expectancy in society has burdened healthcare systems substantially because of the rising prevalence of age -related metabolic diseases. This study compared the effects of animal protein hydrolysate (APH) and casein on metabolic diseases using aged mice. MATERIALS/METHODS: Eight -week-old and 50 -week-old C57BL/6J mice were used as the non -aged (YC group) and aged controls (NC group), respectively. The aged mice were divided randomly into 3 groups (NC, low-APH [LP], and high-APH [HP] and fed each experimental diet for 12 weeks. In the LP and HP groups, casein in the AIN-93G diet was substituted with 16 kcal% and 24 kcal% APH, respectively. The mice were sacrificed when they were 63 -weekold, and plasma and hepatic lipid, white adipose tissue weight, hepatic glucose, lipid, and antioxidant enzyme activities, immunohistochemistry staining, and mRNA expression related to the glucose metabolism on liver and muscle were analyzed. RESULTS: Supplementation of APH in aging mice resulted in a significant decrease in visceral fat (epididymal, perirenal, retroperitoneal, and mesenteric fat) compared to the negative control (NC) group. The intraperitoneal glucose tolerance test and area under the curve analysis revealed insulin resistance in the NC group, which was alleviated by APH supplementation. APH supplementation reduced hepatic gluconeogenesis and increased glucose utilization in the liver and muscle. Furthermore, APH supplementation improved hepatic steatosis by reducing the hepatic fatty acid and phosphatidate phosphatase activity while increasing the hepatic carnitine palmitoyltransferase activity. Furthermore, in the APH supplementation groups, the red blood cell (RBC) thiobarbituric acid reactive substances and hepatic H2O2 levels decreased, and the RBC glutathione, hepatic catalase, and glutathione peroxidase activities increased. CONCLUSIONS: APH supplementation reduced visceral fat accumulation and alleviated obesity -related metabolic diseases, including insulin resistance and hepatic steatosis, in aged mice. Therefore, high -quality animal protein APH that reduces the molecular weight and enhances the protein digestibility -corrected amino acid score has potential as a dietary supplement for healthy aging. | Shin, Su-Kyung; Lee, Ji-Yoon; Bae, Heekyong R.; Park, Hae-Jin; Kwon, Eun-Young | Kyungpook Natl Univ, Dept Food Sci & Nutr, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Ctr Food & Nutr Genom Res, Daegu 41566, South Korea; Daegu Haany Univ, Bio Convergence Testing Ctr, 1 Hanuidae Ro, Gyongsan 38610, South Korea; Kyungpook Natl Univ, Ctr Beautiful Aging, Daegu 41566, South Korea | 23988149900; 58631087000; 57191253762; 7601569369; 15765422500 | hjpark@dhu.ac.kr;eykwon@knu.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 18 | 1 | SCIE | NUTRITION & DIETETICS | 2024 | 1.5 | 77.2 | 0.52 | 2025-05-07 | 1 | 1 | Proteins; aging; visceral fat; insulin resistance; fatty liver; obesity | OXIDATIVE STRESS; LIVER; MUSCLE; ACID; BODY; METABOLISM; REMOVAL; OBESITY; TISSUE; MTOR | aging; fatty liver; insulin resistance; obesity; Proteins; visceral fat | English | 2024 | 2024-02 | 10.4162/nrp.2024.18.1.46 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Kaempferol ameliorates metabolic syndrome by inhibiting inflammation and oxidative stress in high-fat diet-induced obese mice | BACKGROUND/OBJECTIVES: Kaempferol (Ka) is one of the most widely occurring flavonoids found in large amounts in various plants. Ka has anti-obesity, antioxidant, and antiinflammatory effects. Despite the numerous papers documenting the efficacy of Ka, some controversy remains. Therefore, this study examined the impact of Ka using 3T3 -L1 and highfat diet-induced obese mice. MATERIALS/METHODS: 3T3 -L1 cells were treated with 50 mu M Ka from the initiation of 3T3 -L1 differentiation at D0 until the completion of differentiation on D8. Thirty male mice (C57BL/6J, 4 weeks old) were divided into 3 groups: normal diet (ND), high -fat diet (HFD), and HFD + 0.02% (w/w) Ka (Ka) group. All mice were fed their respective diets ad libitum for 16 weeks. The mice were sacrificed, and the plasma and hepatic lipid levels, white adipose tissue weight, hepatic glucose level, lipid level, and antioxidant enzyme activities were analyzed, and immunohistochemistry staining was performed. RESULTS: Ka suppressed the hypertrophy of 3T3 -L1 cells, and the Ka-supplemented mice showed a significant decrease in perirenal, retroperitoneal, mesenteric, and subcutaneous fat compared to the HFD group. Ka supplementation in high -fat diet-induced obese mice also improved the overall blood lipid concentration (total cholesterol, non-high-density lipoprotein-cholesterol, phospholipids, and apolipoprotein B). Ka supplementation in highfat-induced obesity mice reduced hepatic steatosis and insulin resistance by modulating the hepatic lipid (glucose-6-phosphate dehydrogenase, fatty acid synthase, malic enzyme, phosphatidate phosphohydrolase, and beta -oxidation) activities and glucose (glucokinase, phosphoenolpyruvate carboxykinase, and G6pase)-regulating enzymes. Ka supplementation ameliorated the erythrocyte and hepatic mitochondrial H 2 O 2 and inflammation levels (plasma tumor necrosis factor-alpha, monocyte chemoattractant protein -1, interleukin-6, and interferon -gamma and fibrosis of liver and epididymal fat). CONCLUSION: Ka may be beneficial for preventing diet-induced obesity, inflammation, oxidative stress, and diabetes. | Shin, Su-Kyung; Kwon, Eun-Young | Kyungpook Natl Univ, Dept Food Sci & Nutr, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Ctr Food & Nutr Genom Res, Daegu 41566, South Korea; Kyungpook Natl Univ, Ctr Beautiful Aging, Daegu 41566, South Korea | 23988149900; 15765422500 | eykwon@knu.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 18 | 3 | SCIE | NUTRITION & DIETETICS | 2024 | 1.5 | 77.2 | 1.55 | 2025-05-07 | 2 | 3 | Obesity; inflammation; oxidative stress; fatty liver; metabolic syndrome | INSULIN-RESISTANCE; ADIPOSE-TISSUE; LIVER; DYSFUNCTION; QUERCETIN; ASSAY; RISK; ACID | fatty liver; inflammation; metabolic syndrome; Obesity; oxidative stress | English | 2024 | 2024-06 | 10.4162/nrp.2024.18.3.325 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Current status of intestinal parasite infections in fecal samples of dogs in Korea | This study surveyed the current status of intestinal parasite infections in Korean dog fecal samples. A total of 367 fecal samples were collected from the northern (Seoul and Gyeonggi-do), central (Chungcheong-do), and southern (Gyeongsang-do) regions and analyzed using the saturated sodium nitrate flotation technique and the nucleotide sequences of 18S rRNA. Six species of intestinal parasites were detected using the flotation technique. Among them, helminth eggs detected included Toxocara canis (6.0%), Toxascaris leonina (1.1%), Trichuris vulpis (6.8%), Ancylostoma caninum (2.7%), and Spirometra sp. (1.1%). Additionally, Cystoisospora sp. (7.6%) oocysts were also detected. The prevalence of intestinal parasite infections was higher in shelter dogs than in pet dogs. Molecular genetic assays revealed the gdh and 18S rRNA genes of Giardia duodenalis (type D) in 4.9% of fecal samples. To the best of our knowledge, 18S rRNA genes of Cryptosporidium canis were identified in 1.9% of fecal samples for the first time in Korea. These findings provide an overview of the current status of intestinal parasite infections in fecal samples of dogs from Korea and can be helpful in the surveillance of zoonotic parasite infections related to dogs. | Lee, You-Jeong; Kim, Beoul; Kwak, Dongmi; Seo, Min-Goo | Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Vet Biomed Sci, Daegu 41566, South Korea | Seo, Min-Goo/NQF-4335-2025 | 59343760600; 59343608800; 7007148758; 53982155300 | koreasmg@knu.ac.kr; | PARASITES HOSTS AND DISEASES | PARASITE HOST DIS | 2982-5164 | 2982-6799 | 62 | 4 | SCIE | PARASITOLOGY | 2024 | 1.3 | 77.7 | 0.84 | 2025-05-07 | 1 | 1 | Dog; protozoa; helminths; fecal sample | MOLECULAR-DETECTION; CRYPTOSPORIDIUM; PREVALENCE; GIARDIA; CANIS | Dog; fecal sample; helminths; protozoa | Animals; Dog Diseases; Dogs; Feces; Intestinal Diseases, Parasitic; Prevalence; Republic of Korea; RNA, Ribosomal, 18S; Trichuris; RNA 18S; animal; dog; dog disease; epidemiology; feces; genetics; intestine infection; isolation and purification; parasitology; prevalence; South Korea; Trichuris; veterinary medicine | English | 2024 | 2024-11 | 10.3347/phd.24024 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Genotypic analysis of zoonotic Enterocytozoon bieneusi in wild deer in Korea | Enterocytozoon bieneusi is an important microsporidian protozoa that causes intestinal disorders in humans. We collected 191 fecal samples from roadkill deer carcasses, among which 13 (6.8%) showed positive reaction for E. bieneusi by polymerase chain reaction assay. Phylogenetic analysis revealed 6 distinct genotypes, 1 of which was novel. All genotypes belonged to Group 1, which has low host specificity, indicating possible transmission through sylvatic cycle. E. bieneusi infection was predominant in | Noh, Gyeonguk; Lee, Haeseung; Lee, Seung-Hun; Seo, Min-Goo; Kim, Kyoo-Tae; Lee, Junho; Nazim, Kaifa; Park, Sang Joon; Rhee, Man Hee; Kwak, Dongmi | Kyungpook Natl Univ, Coll Vet Med, Dept Vet Med, Daegu 41566, South Korea; Anim & Plant Quarantine Agcy, Vet Epidemiol Div, Gimcheon 39660, South Korea; Chungbuk Natl Univ, Coll Vet Med, Cheongju 28644, South Korea; Khalsa Coll Vet & Anim Sci, Dept Vet Parasitol, Amritsar 143002, Punjab, India; Kyungpook Natl Univ, Inst Vet Biomed Sci, Coll Vet Med, Daegu 41566, South Korea | nazim, kaifa/KYQ-6586-2024; Rhee, Man/O-5705-2016; Seo, Min-Goo/NQF-4335-2025 | 57220040287; 57202497862; 57203394416; 53982155300; 56680415000; 57219032336; 57205471525; 59331548900; 57211035357; 7007148758 | dmkwak@knu.ac.kr; | PARASITES HOSTS AND DISEASES | PARASITE HOST DIS | 2982-5164 | 2982-6799 | 62 | 4 | SCIE | PARASITOLOGY | 2024 | 1.3 | 77.7 | 0 | 2025-05-07 | 1 | 0 | Enterocytozoon bieneusi; deer; genotyping; zoonosis | deer; Enterocytozoon bieneusi; genotyping; zoonosis | Animals; Deer; DNA, Fungal; Enterocytozoon; Feces; Female; Genotype; Male; Microsporidiosis; Phylogeny; Polymerase Chain Reaction; Republic of Korea; Sequence Analysis, DNA; Zoonoses; fungal DNA; animal; deer; DNA sequencing; Enterocytozoon; epidemiology; feces; female; genetics; genotype; isolation and purification; male; microbiology; microsporidiosis; phylogeny; polymerase chain reaction; South Korea; veterinary medicine; zoonosis | English | 2024 | 2024-11 | 10.3347/phd.24072 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Molecular detection and characterization of Acanthamoeba infection in dogs and its association with keratitis in Korea | Acanthamoeba infection is associated with keratitis in humans; however, its association with keratitis in dogs remains unclear. To investigate this possibility, we collected 171 conjunctival swab samples from dogs with eye -related diseases (65 with keratitis and 106 without keratitis) at Chungbuk National University Veterinary Teaching Hospital, Korea, from August 2021 to September 2022. Polymerase chain reaction identified 9 samples (5.3%) as Acanthamoeba positive; of these, 3 were from dogs with keratitis (4.6%) and 6 were from dogs without keratitis (5.7%). Our results indicated no significant association between Acanthamoeba infection and keratitis, season, sex, or age. All Acanthamoeba organisms found in this study had the genotype T4, according to 18S ribosomal RNA analysis. Acanthamoeba infection in dogs might have only a limited association with keratitis. | Lee, Subin; Alkathiri, Badriah; Jung, Ji Seung; Kang, Nanyoung; Hwang, Jiyi; Park, Sang-Eun; Hong, Yeonchul; Park, Kyung-Mee; Lee, Seung-Hun | Chungbuk Natl Univ, Coll Vet Med, Cheongju 28644, South Korea; Kyungpook Natl Univ, Sch Med, Dept Parasitol & Trop Med, Daegu 41944, South Korea | 57776738900; 57190979864; 58536889100; 58536690600; 58536845700; 58536929800; 7403392847; 54585766300; 57203394416 | parkkm@chungbuk.ac.kr;dvmshlee@chungbuk.ac.kr; | PARASITES HOSTS AND DISEASES | PARASITE HOST DIS | 2982-5164 | 2982-6799 | 62 | 1 | SCIE | PARASITOLOGY | 2024 | 1.3 | 77.7 | 2.51 | 2025-05-07 | 3 | 3 | Acanthamoeba; Acanthamoeba keratitis; dog; genotype T4; clinical case | CANARY-ISLANDS; IDENTIFICATION; GENOTYPE; TENERIFE; GENUS; SPP. | Acanthamoeba; Acanthamoeba keratitis; clinical case; dog; genotype T4 | Acanthamoeba; Amebiasis; Animals; Dogs; Hospitals, Animal; Hospitals, Teaching; Humans; Keratitis; Republic of Korea; Acanthamoeba; amebiasis; animal; dog; epidemiology; genetics; human; keratitis; South Korea; teaching hospital; veterinary clinic | English | 2024 | 2024-02 | 10.3347/phd.23112 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Molecular survey of Toxoplasma gondii B1 gene in pigs from various localities in Korea | Toxoplasma gondii, , a common protozoan parasite, poses significant public health risks due to its potential to cause toxoplasmosis in humans and can be contracted from pigs, which are considered its critical intermediate host. The aim of this study is to evaluate the prevalence of T. gondii in slaughtered pigs for human consumption, emphasizing the zoonotic implications and the need for improved biosecurity and monitoring practices in pig farming. A total of 1,526 pig samples (1,051 whole blood samples and 384 lung tissue samples from the local slaughterhouse and 91 aborted fetus samples from local farms) were collected throughout the whole country of Korea in 2020. Among them, 6 (0.4%) were found to be infected with T. gondii by nested PCR. When compared by sample type, the prevalence of T. gondii was significantly higher in the aborted fetus samples (2.2%, 2/91) than in the blood (0.3%, 3/1,051) and lung tissue samples (0.3%, 1/384). The B1 gene sequence of T. gondii was similar (97.9-99.8%) to that of the other T. gondii isolates. This study represents the first molecular genotyping survey of T. gondii in the lung tissue of fattening pigs and aborted fetuses in Korea. Our findings indicated the importance of adopting preventive measures including the implementation of rigorous farm hygiene protocols and the promotion of public awareness about the risks of consuming undercooked pork. By addressing the gaps in current control strategies and encouraging the One Health approach, this study contributes to the development of more effective strategies to mitigate the transmission of T. gondii from pigs to humans, ultimately safeguarding public health. | Kwak, Dongmi; Seo, Min-Goo | Kyungpook Natl Univ, Coll Vet Med, Inst Vet Biomed Sci, Daegu 41566, South Korea | ; Seo, Min-Goo/NQF-4335-2025 | 7007148758; 53982155300 | koreasmg@knu.ac.kr; | PARASITES HOSTS AND DISEASES | PARASITE HOST DIS | 2982-5164 | 2982-6799 | 62 | 3 | SCIE | PARASITOLOGY | 2024 | 1.3 | 77.7 | 0.84 | 2025-05-07 | 1 | 1 | Toxoplasma gondii; pig; molecular epidemiology; genotyping; Korea | IDENTIFICATION; PORK | genotyping; Korea; molecular epidemiology; pig; Toxoplasma gondii | Abattoirs; Aborted Fetus; Animals; DNA, Protozoan; Genotype; Humans; Lung; Polymerase Chain Reaction; Prevalence; Republic of Korea; Swine; Swine Diseases; Toxoplasma; Toxoplasmosis, Animal; protozoal DNA; animal; animal toxoplasmosis; epidemiology; fetus death; genetics; genotype; human; isolation and purification; lung; parasitology; pig; polymerase chain reaction; prevalence; slaughterhouse; South Korea; swine disease; Toxoplasma | English | 2024 | 2024-08 | 10.3347/phd.24031 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Population genetic analysis of Plasmodium vivax vir genes in Pakistan | Plasmodium vivax variant interspersed repeats (vir) vir ) refer to the key protein used for escaping the host immune system. Knowledge in the genetic variation of vir genes can be used for the development of vaccines or diagnostic methods. Therefore, we evaluated the genetic diversity of the vir genes of P. vivax populations of several Asian countries, including Pakistan, which is a malaria-endemic country experiencing a significant rise in malaria cases in recent years. We analyzed the genetic diversity and population structure of 4 vir genes ( vir 4, vir 12, vir 21, and vir 27) in the Pakistan P. vivax population and compared these features to those of the corresponding vir genes in other Asian countries. In Pakistan, vir 4 (S= 198, H= 9, Hd = 0.889, Tajima's D value =1.12321) was the most genetically heterogenous, while the features of vir 21 (S= 8, H= 7, Hd=0.664, Tajima's D value=-0.63763) and vir 27 (S = 25, H = 11, Hd = 0.682, Tajima's D value=-2.10836) were relatively conserved. Additionally, vir 4 was the most genetically diverse among Asian P. vivax populations, although within population diversity was low. Meanwhile, vir 21 and vir 27 among all Asian populations were closely related genetically. Our findings on the genetic diversity of vir genes and its relationships between populations in diverse geographical locations contribute toward a better understanding of the genetic characteristics of vir. . The high level of genetic diversity of vir 4 suggests that this gene can be a useful genetic marker for understanding the P. vivax population structure. Longitudinal genetic diversity studies of vir genes in P. vivax isolates obtained from more diverse geographical areas are needed to better understand the function of vir genes and their use for the development of malaria control measures, such as vaccines. | Dinzouna-Boutamba, Sylvatrie-Danne; Moon, Zin; Lee, Sanghyun; Afridi, Sahib Gul; Hong, Yeonchul; Na, Byoung-Kuk; Goo, Youn-Kyoung | Kyungpook Natl Univ, Sch Med, Dept Parasitol & Trop Med, Daegu 700422, South Korea; Abdul Wali Khan Univ Mardan, Dept Biochem, Mardan, Pakistan; Gyeongsang Natl Univ, Coll Med, Dept Parasitol & Trop Med, Dept Convergence Med Sci, Jinju 52727, South Korea; Gyeongsang Natl Univ, Inst Hlth Sci, Coll Med, Jinju 52727, South Korea; Kyungpook Natl Univ, Inst Vet Biomed Sci, Coll Vet Med, Daegu 41566, South Korea | Afridi, Sahib/AGH-9949-2022 | 56299947300; 57223389298; 56272461500; 36607439500; 57200567418; 7403392847; 7005291099; 22937863200 | bkna@gnu.ac.kr;ykg.kuku1819@knu.ac.kr; | PARASITES HOSTS AND DISEASES | PARASITE HOST DIS | 2982-5164 | 2982-6799 | 62 | 3 | SCIE | PARASITOLOGY | 2024 | 1.3 | 77.7 | 0.84 | 2025-05-07 | 1 | 1 | Plasmodium vivax; Pakistan; vir; population structure; genetic diversity | DIVERSITY; SPLEEN; PFEMP1 | genetic diversity; Pakistan; Plasmodium vivax; population structure; vir | Genetic Variation; Genetics, Population; Humans; Malaria, Vivax; Pakistan; Plasmodium vivax; Protozoan Proteins; protozoal protein; epidemiology; genetic variation; genetics; human; Pakistan; parasitology; Plasmodium vivax; Plasmodium vivax malaria; population genetics | English | 2024 | 2024-08 | 10.3347/phd.24036 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | An Analysis Method of Heat and Light Detection with Scintillating Crystals | We present an analysis method for determining signal amplitudes using a least squares method in combination with an optimally selected bandpass filter. This method has been developed to process heat and light signals obtained in the AMoRE-I experiment. We apply Butterworth filters with various combinations of passbands and filter orders to both the heat and light signals. Subsequently, we employ the least squares method to calculate signal amplitudes by comparing each signal template for the heat and light channels. Optimal filter conditions are identified to achieve the best resolution value. In this paper, we provide a detailed description of the signal processing approach, comparing it with the optimal filter method. | Lim, H. S.; Chung, J. S.; Jo, H. S.; Kim, H. B.; Kim, H. L.; Kim, Y. H.; Kim, W. T.; Kwon, D. H.; Lee, D. Y.; Lee, Y. C.; Woo, K. R. | Kyungpook Natl Univ, Dept Phys, Daehakro 80, Daegu 41566, South Korea; Univ Sci & Technol, Inst Basic Sci Sch, Exporo 55, Daejeon 34126, South Korea; Seoul Natl Univ, Dept Phys, Gwanakro 1, Seoul 08826, South Korea; Inst for Basic Sci Korea, Ctr Underground Phys, Exporo 55, Daejeon 34126, South Korea | ; Kim, Hong Joo/AAE-1178-2022; Lee, Yong Jae/GLR-4153-2022; Jo, Hyon-Suk/HGC-7070-2022; Lee, You/T-6086-2019 | 57907833600; 58194129700; 35227429400; 55195026700; 57218825747; 57196171764; 57211502868; 57201795741; 58848262200; 57203244766; 57211276680 | hyonsuk@knu.ac.kr;hanbum7@snu.ac.kr;krwoo@ust.ac.kr; | JOURNAL OF LOW TEMPERATURE PHYSICS | J LOW TEMP PHYS | 0022-2291 | 1573-7357 | 217 | 3-4 | SCIE | PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2024 | 1.4 | 77.8 | 0.37 | 2025-05-07 | 1 | 1 | Signal processing; Optimal filter method; Least squares method; Neutrinoless double beta decay; Butterworth filter; Thermal calorimeter | CALORIMETERS | Butterworth filter; Least squares method; Neutrinoless double beta decay; Optimal filter method; Signal processing; Thermal calorimeter | Bandpass filters; Crystal filters; Crystals; Least squares approximations; Signal processing; Analysis method; Filter method; Least-squares- methods; Neutrinoless double-beta decays; Optimal filter; Optimal filter method; Signal amplitude; Signal-processing; Thermal; Thermal calorimeter; Butterworth filters | English | 2024 | 2024-11 | 10.1007/s10909-024-03191-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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