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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Synergistic Effect of Venetoclax and Bendamustine in Early T-cell Precursor Acute Lymphoblastic Leukemia | Background/Aim: To date, therapeutic options for Tcell acute lymphoblastic leukemia (T -ALL) remain very limited. This study evaluated the efficacy of monotherapies and combination therapies including a selective BCL-2 inhibitor for T -ALL cell lines, namely Jurkat, CCRF-CEM, and Loucy. Materials and Methods: Loucy is an early T -precursor ALL (ETP-ALL) cell line characterized by an immature phenotype, whereas Jurkat and CCRF-CEM are late T -cell progenitor ALL (LTP-ALL) cell lines. Monotherapy was conducted with venetoclax, cytarabine, bendamustine, or azacytidine, whereas combination therapy was performed with venetoclax plus cytarabine, venetoclax plus bendamustine, or venetoclax plus azacytidine. Cell viability assay was conducted after 48 h using Trypan blue and the 3-(4, 5-dimethylthiazol-2-yl)-5-(3carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS). Statistical analysis for evaluating synergistic interactions between anticancer drugs was performed by using the SynergyFinder Plus and drc R package. Results: Adding venetoclax to cytarabine, bendamustine, or azacitidine achieved an additive effect, with Loewe synergic scores ranging from - 10 to 10 in Jurkat and CCRF-CEM. Conversely, the combination of venetoclax and cytarabine displayed an additive effect (Loewe synergic score: 8.45 and 5.82 with MTS and Trypan blue assays, respectively), whereas venetoclax plus bendamustine or azacitidine exhibited a synergistic effect (Loewe synergic score >10 with MTS assay) in Loucy. Remarkably, the Bliss/Loewe score revealed that the combination of venetoclax and bendamustine was the most synergistic, yielding a score of 13.832 +/- 0.55. Conclusion: The combination of venetoclax and bendamustine demonstrated the greatest synergistic effect in suppressing ETP-ALL cell proliferation. Further studies are warranted to determine the mechanisms for the synergism between venetoclax and bendamustine in high -risk T -ALL. | Nguyen, Hong Duc Thi; Le, Tan Minh; Lee, Donghyeon; Cho, Hee Jeong; Lee, Jungmin; Sohn, Sang Kyun; Kim, Jong Gwang; Ham, Ji Yeon; Moon, Joon Ho; Han, Hyung Soo; Kim, Juhyung; Baek, Dong Won | Kyungpook Natl Univ, Grad Sch, Dept Biomed Sci, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Four Program BK21, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Hematol Oncol, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Hematol Oncol, 807 Hoguk Ro, Daegu 41404, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Lab Med, Daegu, South Korea | ; Le, Tan/ITT-2150-2023 | 57870555300; 57870749600; 57870503500; 57216754907; 57211561890; 13310226800; 59501049300; 56464754800; 56568642700; 7401969388; 58739544500; 57191874272 | dnakim1@gmail.com;baekdw83@gmail.com; | IN VIVO | IN VIVO | 0258-851X | 1791-7549 | 38 | 4 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL | 2024 | 1.8 | 70.5 | 0.44 | 2025-05-07 | 3 | 2 | ETP-ALL; venetoclax; bendamustine; MTS assay; Bliss/Loewe consensus score | AZACITIDINE; MANAGEMENT; ADULTS; BCL-2; LINE | bendamustine; Bliss/Loewe consensus score; ETP-ALL; MTS assay; venetoclax | Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bendamustine Hydrochloride; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Humans; Jurkat Cells; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Sulfonamides; azacitidine; bendamustine; cytarabine; trypan blue; venetoclax; antineoplastic agent; bendamustine; fused heterocyclic rings; sulfonamide; venetoclax; additive effect; Article; cancer combination chemotherapy; CCRF-CEM cell line; cell proliferation; cell viability assay; comparative effectiveness; controlled study; dose response; drug efficacy; drug potentiation; drug sensitivity; early cancer; human; human cell; IC50; Jurkat cell line; Loewe synergic score; monotherapy; MTS assay; scoring system; T cell acute lymphoblastic leukemia; trypan blue assay; apoptosis; cell survival; drug effect; drug therapy; pathology; tumor cell line | English | 2024 | 2024 (JUL-AUG) | 10.21873/invivo.13624 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A Study on the Effectiveness of Helmet Therapy for Cranial Deformations According to Cranial Shape | Background:To investigate the effects of helmet therapy on plagiocephaly, according to head circumference, cephalic index (CI), and skull height. Plagiocephaly is a condition in which the skull is congenitally asymmetrical or affected by acquired factors such as compression in the womb or the habit of sleeping on one side. Although there are numerous studies on the effectiveness of helmet therapy for plagiocephaly, research on its effectiveness on skull shape is lacking.Methods:We conducted a prospective study on 400 patients who underwent helmet therapy. The infants were enrolled and the therapy was explained to the caregiver when the child had positional plagiocephaly and had a cranial vault asymmetry (CVA) exceeding 10 mm or a CVA index (CVAI) exceeding 3.5%. The CVA and CVAI changes were compared to investigate the effectiveness of helmet therapy according to head circumference, CI, and skull height.Results:A significant treatment effect was observed for CI values between 90 and 103. The treatment effect was found to increase with greater skull height. However, no significant difference was observed in the effectiveness of helmet therapy according to head circumference.Conclusions:According to the findings, the effectiveness of helmet therapy in children with positional plagiocephaly is greater for children with higher skulls and for those with CI values between 90 and 103; it is unrelated to head circumference. Based on these results, we can provide predictions of the effectiveness of helmet therapy to caregivers of children with positional plagiocephaly. | Cho, Hyun Geun; Ryu, Jeong Yeop; Lee, Joon Seok; Yang, Jung Dug; Chung, Ho Yun; Choi, Kang Young | Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, Daegu 41944, South Korea | Ryu, Jeong Yeop/GLQ-9419-2022; Yang, Jung/R-7806-2019 | 57211205767; 56366349400; 56496041000; 55171704700; 7404007181; 57203745682 | cg2448@naver.com;prsryu@knu.ac.kr;leejspo@knu.ac.kr;lambyang@knu.ac.kr;chunghoyun@gmail.com;prschoi@gmail.com;kychoi@knu.ac.kr; | JOURNAL OF CRANIOFACIAL SURGERY | J CRANIOFAC SURG | 1049-2275 | 1536-3732 | 35 | 3 | SCIE | SURGERY | 2024 | 1 | 70.7 | 0 | 2025-05-07 | 0 | 0 | Cephalic index; head circumference; positional plagiocephaly; skull height | INFANTS | Cephalic index; head circumference; positional plagiocephaly; skull height | English | 2024 | 2024-05 | 10.1097/scs.0000000000010018 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Bilateral Nostril Abrasion in Endoscopic Sinus Surgery with Micodebrider | The emergence of microdebrider technology has revolutionized endoscopic sinus surgery (ESS). Although widely used, it has been associated with complications such as cerebrospinal fluid leakage, ocular and brain injuries, and synechia formation. However, reports on cases of skin abrasion associated with the use of microdebriders in ESS are scarce. We herein present a unique observation of bilateral nostril abrasion after ESS using the microdebrider in a 53-year-old man. The patient underwent ESS and septoplasty for nasal obstruction and polyps. Bilateral nostril erythema and skin abrasion were observed after surgery, which resolved without scarring. Nostril abrasion is attributed to the lever-like use of the microdebrider against the medial aspect of the nostril during the procedure, particularly among inexperienced surgeons. This prompts the need for a cautious approach when using microdebriders in ESS to minimize complications. Increased awareness and precautionary measures can enhance the safety of microdebriders in ESS. | Oh, Eun Jung; Kim, Jung Soo; Heo, Sung Jae | Kyungpook Natl Univ, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Otorhinolaryngol Head & Neck Surg, 807 Hoguk Ro, Daegu 41404, South Korea | 허, 성재/AAU-3921-2020 | 57844473100; 55720132500; 55822906000 | entnose@kakao.com;profsookim@gmail.com;blueskyhsj@hanmail.net; | JOURNAL OF CRANIOFACIAL SURGERY | J CRANIOFAC SURG | 1049-2275 | 1536-3732 | 35 | 2 | SCIE | SURGERY | 2024 | 1 | 70.7 | 0 | 2025-05-07 | 0 | 0 | Complications; endoscopy; microdebrider; sinus | Complications; endoscopy; microdebrider; sinus | Debridement; Endoscopy; Erythema; Humans; Male; Middle Aged; Nasal Obstruction; Nasal Polyps; Nasal Septum; Nose; Postoperative Complications; case report; debridement; endoscopy; erythema; etiology; human; male; middle aged; nose; nose obstruction; nose septum; postoperative complication; procedures; sinonasal polyp; surgery | English | 2024 | 2024 (MAR-APR) | 10.1097/scs.0000000000009757 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Chemical Burn Injury on the Cornea Following Skin Preparation With Chlorhexidine in Tonsillectomy and Adenoidectomy | This article report discusses a pediatric patient who suffered a corneal chemical burn injury after tonsillectomy and adenoidectomy surgery due to skin preparation with chlorhexidine. In this case, inadequate sealing of the eye shield during skin preparation allowed the chlorhexidine-alcohol solution to accumulate at its edge and gradually penetrate, resulting in the corneal injury. Prompt ophthalmological intervention and appropriate eye care treatment led to a gradual improvement in the patient's symptoms. The authors aim to present the case, share the revisions made to our skin preparation policy, and emphasize the importance of cautious antiseptic use to minimize the risk of adverse events. Adverse effects of chlorhexidine, such as hypersensitivity reactions and burns, including corneal damage, are highlighted. Health care providers should exercise caution when selecting and applying antiseptics, considering patient-specific factors, and comprehensive training should be provided to promote adherence to safe antiseptic practices during surgical procedures. | Oh, Eun Jung; Kim, Jung Soo; Heo, Sung Jae | Kyungpook Natl Univ, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Otorhinolaryngol Head & Neck Surg, 807 Hoguk Ro, Daegu 41404, South Korea | 허, 성재/AAU-3921-2020 | 57844473100; 55720132500; 55822906000 | entnose@kakao.com;profsookim@gmail.com;blueskyhsj@hanmail.net; | JOURNAL OF CRANIOFACIAL SURGERY | J CRANIOFAC SURG | 1049-2275 | 1536-3732 | 35 | 2 | SCIE | SURGERY | 2024 | 1 | 70.7 | 0 | 2025-05-07 | 0 | 0 | Anti-infective agents; chemical burns; chlorhexidine; corneal injuries | POVIDONE-IODINE; ANTISEPSIS | Anti-infective agents; chemical burns; chlorhexidine; corneal injuries | Adenoidectomy; Anti-Infective Agents, Local; Burns, Chemical; Child; Chlorhexidine; Corneal Injuries; Female; Humans; Male; Preoperative Care; Tonsillectomy; chlorhexidine; topical antiinfective agent; adenoidectomy; adverse event; case report; chemical burn; child; cornea injury; etiology; female; human; male; preoperative care; surgery; tonsillectomy | English | 2024 | 2024 (MAR-APR) | 10.1097/scs.0000000000009755 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effectiveness of Atherectomy and Drug-Coated Balloon Angioplasty in Femoropopliteal Disease: A Comprehensive Outcome Study | Purpose: Atherectomy has been reintroduced for debulking calcified atheroma to enhance the efficacy of drug-coated balloons (DCBs); however, its efficacy in severe calcification and related outcomes have not been fully evaluated. This study aimed to evaluate the outcomes of atherectomy and DCB angioplasty for treating femoropopliteal occlusive disease (FPOD). Materials and Methods: From 2014 to July 2022, 85 limbs in 76 patients with FPOD underwent atherectomy with DCB angioplasty. We evaluated the efficacy of this procedure using primary patency (PP) and clinically driven target lesion revascularization (CD-TLR)-free survival. PP was defined as the duration of uninterrupted patency without occlusion or a peak systolic velocity ratio more than 2.5 at the target lesion. Lesion calcification was evaluated according to Peripheral Arterial Calcium Scoring System, and Grade 4 was classified as severe. Results: Seventy-one (84%) cases were male, and 56 limbs (66%) were treated for claudication. Rotational and directional atherectomies were performed in 62 (73%) and 23 limbs, respectively. The improvement in the median ankle-brachial index was 0.36 (interquartile range, 0.25-0.48). Median follow-up duration was 19.4 months. The overall PP and CD-TLR-free survival rates were 77% and 93% at 1 year and 64% and 83% at 2 years, respectively. On multivariable analysis, female sex (adjusted hazard ratio [aHR], 3.77; 95% confidence interval (CI), 1.30-10.87, P=0.014), dialysis (aHR, 4.35; 95% CI, 1.33-13.22, P=0.015), and severe calcification (aHR, 2.42; 95% CI, 1.07-5.46, P=0.033) were independent risk factors for poor PP. Dialysis (aHR, 11.07; 95% CI, 3.72-32.92, P<0.001) and severe calcification (aHR, 3.19; 95% CI, 1.15-8.84, P=0.026) were identified as independent risk factors for CD-TLR. Conclusion: Atherectomy with DCB angioplasty for FPOD did not work well in female patients, patients with lesions with severe calcification, and patients undergoing dialysis. Therefore, careful monitoring of these patients is crucial for patency loss and the requirement for revascularization. Additionally, for these patients requiring revascularization, surgical bypass may be appropriate for suitable candidates; whereas more proactive conservative management may be justified for claudicants. | Kim, Hyeon Ju; Nwang, Deokbi; Yun, Woo-Sung; Huh, Seung; Kim, Hyung-Kee | Kyungpook Natl Univ, Dept Surg, Div Vasc & Endovascular Surg, Chilgok Hosp, 807 Hoguk, Daegu 41404, South Korea; Kyungpook Natl Univ, Sch Med, Kyungpook Natl Univ Hosp, Div Vasc & Endovascular Surg,Dept Surg, Daegu, South Korea | SeungTaek, lim/C-8232-2015; Kim, Hyung-Kee/JBR-8125-2023 | 58202135200; 57194422879; 35070717000; 7101832929; 35169819900 | hkkim6260@knu.ac.kr; | VASCULAR SPECIALIST INTERNATIONAL | VASC SPEC INT | 2288-7970 | 2288-7989 | 40 | ESCI | PERIPHERAL VASCULAR DISEASE;SURGERY | 2024 | 1 | 70.7 | 0.8 | 2025-05-07 | 1 | 2 | Atherectomy; Drug-coated balloon; Peripheral arterial disease; Vascular patency; Revascularization | ARTERIAL CALCIFICATION; ENDOVASCULAR TREATMENT; SOCIETY | Atherectomy; Drug-coated balloon; Peripheral arterial disease; Revascularization; Vascular patency | acetylsalicylic acid; clopidogrel; heparin; hydroxymethylglutaryl coenzyme A reductase inhibitor; acute heart infarction; aged; ankle brachial index; artery calcification; Article; atherectomy; chronic total occlusion; claudication; clinical outcome; computer assisted tomography; congestive heart failure; controlled study; critical limb ischemia; diabetes mellitus; directional atherectomy; disease severity; echography; female; femoral artery; femoropopliteal occlusive disease; fluoroscopy; follow up; human; kidney failure; major clinical study; male; medical device complication; medical record review; peak systolic velocity; percutaneous transluminal angioplasty; peripheral arterial disease; popliteal artery; renal replacement therapy; retrospective study; risk factor; rotational atherectomy; scoring system; sex difference; subsartorial artery; survival rate; target lesion revascularization; thrombus aspiration; treatment free survival; vascular patency | English | 2024 | 2024-09 | 10.5758/vsi.240071 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Editorial Material | Historical Perspectives of the Korean Society for Thoracic and Cardiovascular Surgery: Sung Haing Lee (1919-2012), Who Performed the First Open Heart Surgery Using Hypothermia in Korea | Jung, Hanna; Park, Kook-Yang; Oh, Tae Yun; Kim, Wooshik | Korean Soc Thorac & Cardiovasc Surg, Hist Records Preservat Comm, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Thorac & Cardiovasc Surg, Daegu, South Korea; Gachon Univ, Gil Med Ctr, Incheon, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Seoul, South Korea; Natl Med Ctr, Dept Cardiothorac Surg, Seoul, South Korea | Jung, Hanna/Y-4165-2019 | 56467570700; 56796996800; 14523197200; 58591990000 | navybluesail@knu.ac.kr; | JOURNAL OF CHEST SURGERY | J CHEST SURG | 2765-1606 | 2765-1614 | 57 | 1 | ESCI | CARDIAC & CARDIOVASCULAR SYSTEMS;RESPIRATORY SYSTEM;SURGERY | 2024 | 1 | 70.7 | 0 | 2025-04-16 | 0 | 0 | English | 2024 | 2024-01 | 10.5090/jcs.23.089 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Outcomes of Surgical and Endovascular Treatment for Cephalic Arch Stenosis in Proximal Arteriovenous Fistula | Purpose: The cephalic arch is a significant site of stenosis in proximal arteriovenous fistulas (AVFs) that contributes to access dysfunction and thrombosis. This study aimed to evaluate the outcomes of surgical treatment (ST) and endovascular treatment (ET) for cephalic arch stenosis (CAS). Materials and Methods: A total of 62 patients with proximal AVF who underwent CAS revision using either ST or ET were enrolled between January 2018 and March 2023. In the ET group, only the initial ET following AVF formation was considered, to mitigate bias. In the ST group, central transposition of the native AVF (transposition group) or interposition of the prosthetic graft into the proximal basilic or axillary vein (interposition group) was performed. We evaluated primary and functional patency based on these groups and calculated the number of patency loss events after CAS treatment. Results: Of the 62 patients, 38 (61%) were male, with a mean age of 66.4 years. ST was performed in 26 (42%) patients, including transposition in 16 and interposition in 10, whereas ET was administered to 36 patients during the study period. Among the ST recipients, 42% had a history of ET for CAS. The incidence of AVF thrombosis was marginally higher in the ST group than in the ET group (39% vs. 19%, P=0.098). The primary patency rates at 6 months, 1 year, and 3 years were 87%, 87%, and 66% in the transposition group; 45%, 23%, and 11% in the interposition group; and 66%, 49%, and 17% in the ET group, respectively. Notably, the primary patency of the transposition group was significantly higher than that of the interposition (P=0.001) and ET groups (P=0.016). The frequency of patency loss events per person-year after the initial revision was 0.40, 0.52, and 1.42 in the transposition, interposition, and ET groups, respectively. Conclusion: Transposition exhibited the most favorable primary patency rate and the lowest number of subsequent patency loss events during follow-up despite the higher rates of AVF thrombosis and previous ET at presentation. Consequently, transposition should be actively considered in eligible patients with CAS. | Park, Young Ryul; Jung, Ji Hyun; Hwang, Deokbi; Yun, Woo-Sung; Huh, Seung; Kim, Hyung-Kee | Kyungpook Natl Univ Hosp, Dept Surg, Div Vasc & Endovasc Surg, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Surg,Div Vasc & Endovasc Surg, Daegu, South Korea | ; Kim, Hyung-Kee/JBR-8125-2023 | 59138965700; 57702330600; 57194422879; 35070717000; 7101832929; 35169819900 | hkkim6260@knu.ac.kr; | VASCULAR SPECIALIST INTERNATIONAL | VASC SPEC INT | 2288-7970 | 2288-7989 | 40 | ESCI | PERIPHERAL VASCULAR DISEASE;SURGERY | 2024 | 1 | 70.7 | 0 | 2025-05-07 | 1 | 0 | Cephalic arch; Hemodialysis; Treatment outcome; Surgical procedures; Endovascular procedures | HEMODIALYSIS FISTULAS; VASCULAR ACCESS; MANAGEMENT; GRAFTS; VEIN | Cephalic arch; Endovascular procedures; Hemodialysis; Surgical procedures; Treatment outcome | aged; arm swelling; arteriovenous fistula; Article; axillary vein; blood vessel graft; cephalic vein; clinical outcome; comparative study; endovascular surgery; female; follow up; graft recipient; hemodialysis; human; incidence; major clinical study; male; percutaneous transluminal angioplasty; poor general condition; practice guideline; retrospective study; stenosis; thrombosis; treatment indication; treatment outcome; vascular patency; venous pressure | English | 2024 | 2024-06 | 10.5758/vsi.240015 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Postrhinoplasty Nasal Radix Cyst Treated with Endoscopic Marsupialization | Postrhinoplasty nasal radix cyst is a rare late complication, with few cases being reported in the literature. The appropriate treatment for this cyst is surgical removal. To date, an open approach or intracartilagenous incision has been performed in most cases. Herein, we present a case of a 68-year-old man with a bulging mass of radix who visited our clinic. The patient underwent open surgery for the mass, but the mass recurred 2 years after surgery. Although removal using the open approach was planned as in the previous surgery, marsupialization was performed because a connection with the frontal recess was seen on a computed tomography scan. We report a rare case of nasal radix cyst successfully treated with marsupialization without an external scar. | Kwon, Ha Gyung; Kim, Jung Soo; Heo, Sung Jae | Kyungpook Natl Univ, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Otorhinolaryngol Head & Neck Surg, 807 Hoguk Ro, Daegu 41404, South Korea | 허, 성재/AAU-3921-2020 | 58785879200; 55720132500; 55822906000 | entnose@kakao.com;profsookim@gmail.com;blueskyhsj@hanmail.net; | JOURNAL OF CRANIOFACIAL SURGERY | J CRANIOFAC SURG | 1049-2275 | 1536-3732 | 35 | 2 | SCIE | SURGERY | 2024 | 1 | 70.7 | 0 | 2025-05-07 | 0 | 0 | Complication; cyst; rhinoplasty | Complication; cyst; rhinoplasty | Aged; Cysts; Endoscopy; Humans; Male; Nose Diseases; Postoperative Complications; Recurrence; Rhinoplasty; Tomography, X-Ray Computed; aged; case report; cyst; endoscopy; etiology; human; male; nose disease; postoperative complication; procedures; recurrent disease; rhinoplasty; surgery; x-ray computed tomography | English | 2024 | 2024 (MAR-APR) | 10.1097/scs.0000000000009821 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Raynaud's Phenomenon: A Current Update on Pathogenesis, Diagnostic Workup, and Treatment | Raynaud's phenomenon (RP) is a condition characterized by episodic, excessive vasoconstriction in the fingers and toes, triggered by cold or stress. This leads to a distinctive sequence of color changes in the digits. Pallor indicates reduced blood flow due to oxygen deprivation, while erythema appears as reperfusion. RP can be primary, with no identifiable underlying cause, or secondary, associated with other conditions. These conditions include autoimmune diseases, most commonly systemic sclerosis, vascular diseases; and neurological conditions. While the exact cause of RP remains unclear, genetic and hormonal (estrogen) factors are likely contributors. The pathogenesis of RP involves a complex interaction between the vascular wall, nerves, hormones, and humoral factors, disrupting the balance between vasoconstriction and vasodilation. In primary RP, the vascular abnormalities are primarily functional. However, in secondary RP, both functional and structural components occur in blood vessels. This explains why digital tissue damage frequently occurs in secondary RP but not primary RP. Diagnosis of RP is primarily clinical. Recent advancements in imaging techniques have aided in diagnosis and monitoring, but nail fold capillaroscopy remains the gold standard for distinguishing between primary and secondary RP. If there are signs of acute ischemic injury, vascular imaging, particularly preoperatively, is crucial to rule out other vasoocclusive conditions. Management of RP focuses on alleviating symptoms and preventing tissue damage. Vasodilator medications are the first-line treatment when general measures like warmth and stress management are not sufficient. Dihydropyridine calcium channel blockers (CCBs), such as nifedipine, are commonly used for vasodilation. Phosphodiesterase-5 inhibitors and prostaglandin analogs are alternative options for patients who do not respond to CCBs or have ischemic tissue damage. Bosentan, an endothelin-1 receptor antagonist, has shown effectiveness in treating and preventing digital ulcers, especially in patients with multiple ulcers. For severe cases, botulinum toxin injections or sympathectomy surgery can be used to control RP symptoms. However, botulinum toxin injections require repeated administration, and sympathectomy's long-term effectiveness is uncertain. Fat grafting is a promising surgical therapy for promoting healing and preventing tissue injury. | Ture, Hirut Yadeta; Lee, Nan Young; Kim, Na Ri; Nam, Eon Jeong | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Rheumatol, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Clin Pathol, Daegu, South Korea | 58112648500; 57209204358; 58113116000; 7005824293 | ejnam@knu.ac.kr; | VASCULAR SPECIALIST INTERNATIONAL | VASC SPEC INT | 2288-7970 | 2288-7989 | 40 | ESCI | PERIPHERAL VASCULAR DISEASE;SURGERY | 2024 | 1 | 70.7 | 1.87 | 2025-05-07 | 5 | 5 | Raynaud's phenomenon; Pathogenesis; Diagnosis; Imaging; Management | SYSTEMIC-SCLEROSIS; DIGITAL ULCERS; DOUBLE-BLIND; MICROVASCULAR DAMAGE; PHENOMENON SECONDARY; BOTULINUM TOXIN; ISCHEMIC ULCERS; BOSENTAN; THERAPY; HAND | Diagnosis; Imaging; Management; Pathogenesis; Raynaud’s phenomenon | bosentan; botulinum toxin; calcium channel blocking agent; endothelin; endothelin 1; humoral antibody; nifedipine; vasodilator agent; bleeding; blood flow; blood vessel injury; capillaroscopy; clinical article; controlled study; diagnosis; drug therapy; erythema; finger ulcer; first-line treatment; human; pallor; pathogenesis; Raynaud phenomenon; review; stress management; sympathectomy; systemic sclerosis; therapy; vasoconstriction; vasodilatation | English | 2024 | 2024-06 | 10.5758/vsi.240047 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Surgical Strategies and Long-Term Outcomes for Complex Coral Reef Aorta with Multisegmental Involvement: A Case Report | Coral reef aorta (CRA) is a rare condition characterized by the distribution of rock-hard calcifications in the visceral part of the aorta, leading to potentially life-threatening symptoms, such as hypertension, congestive heart failure, and limb and visceral ischemia. The patient was a 54-year-old female who presented with leg claudication and was diagnosed with CRA using computed tomography. CRA affected the descending thoracic and abdominal aortas, including the visceral portion, leading to reduced perfusion of both limbs and the left kidney. The surgical intervention involved bypass surgery from the descending thoracic aorta proximal to the CRA to the aortic bifurcation, including reimplantation of the left renal artery. Postoperative recovery was successful and the symptoms resolved. However, the patient experienced decreased right renal function due to CRA progression three years postoperatively. Given the uncertainty regarding the optimal surgical approach for CRA, long-term considerations are crucial for its management. | Kim, Hyung-Kee; Park, Suehyun; Hwang, Deokbi; Yun, Woo-Sung; Huh, Seung | Kyungpook Natl Univ, Div Vasc & Endovasc Surg, Dept Surg, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Div Vasc & Endovasc Surg,Dept Surg, Daegu, South Korea | ; Kim, Hyung-Kee/JBR-8125-2023 | 35169819900; 58081703400; 57194422879; 35070717000; 7101832929 | shuh@knu.ac.kr; | VASCULAR SPECIALIST INTERNATIONAL | VASC SPEC INT | 2288-7970 | 2288-7989 | 40 | ESCI | PERIPHERAL VASCULAR DISEASE;SURGERY | 2024 | 1 | 70.7 | 0 | 2025-05-07 | 0 | 0 | Coral reef aorta; Vascular calcification; Operative surgical procedure; Renal insufficiency; Intermittent claudication | TAKAYASU-ARTERITIS; ABDOMINAL-AORTA; CALCIFICATION; BYPASS | Coral reef aorta; Intermittent claudication; Operative surgical procedure; Renal insufficiency; Vascular calcification | creatinine; pentetic acid; abdominal aorta; adult; ankle brachial index; aortic arch syndrome; aortic bifurcation; aortic calcification; Article; bypass surgery; case report; celiac artery; clinical article; comorbidity; computed tomographic angiography; computer assisted tomography; coral reef aorta; creatinine blood level; current smoker; estimated glomerular filtration rate; female; follow up; glomerulus filtration rate; human; hyperlipidemia; hypertension; kidney function; middle aged; open surgery; physical examination; pleura effusion; positron emission tomography-computed tomography; surgical approach; thoracic aorta; treatment outcome | English | 2024 | 2024-03 | 10.5758/vsi.230112 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A sparse empirical Bayes approach to high-dimensional Gaussian process-based varying coefficient models | Despite the increasing importance of high-dimensional varying coefficient models, the study of their Bayesian versions is still in its infancy. This paper contributes to the literature by developing a sparse empirical Bayes formulation that addresses the problem of high-dimensional model selection in the framework of Bayesian varying coefficient modelling under Gaussian process (GP) priors. To break the computational bottleneck of GP-based varying coefficient modelling, we introduce the low-cost computation strategy that incorporates linear algebra techniques and the Laplace approximation into the evaluation of the high-dimensional posterior model distribution. A simulation study is conducted to demonstrate the superiority of the proposed Bayesian method compared to an existing high-dimensional varying coefficient modelling approach. In addition, its applicability to real data analysis is illustrated using yeast cell cycle data. | Kim, Myungjin; Goh, Gyuhyeong | Kyungpook Natl Univ, Dept Stat, Daegu 41566, South Korea; Kyungpook Natl Univ, KNU LAMP Res Ctr, Daegu, South Korea; Kyungpook Natl Univ, KNU Inst Basic Sci, Daegu, South Korea | 57216929620; 55964615700 | ggoh@knu.ac.kr; | STAT | STAT-US | 2049-1573 | 13 | 2 | SCIE | STATISTICS & PROBABILITY | 2024 | 0.8 | 71.6 | 0 | 2025-05-07 | 0 | 0 | Bayesian model selection; Gaussian process (GP) priors; high-dimensional data analysis; varying coefficient models | VARIABLE-SELECTION; REGRESSION | Bayesian model selection; Gaussian process (GP) priors; high-dimensional data analysis; varying coefficient models | English | 2024 | 2024-06 | 10.1002/sta4.678 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Application of objective priors for the multivariate Lomax distribution | For a model incorporating the effect of a common environment on several components of a system, a multivariate Lomax distribution (MLD) is generally considered by mixing exponential variables. Objective Bayesian has very good frequentist properties and provides a moderate solution for the prior elicitation which is one of important and difficult issues on Bayesian analysis. In this paper, we develop noninformative priors, such as the probability matching priors and reference priors, for the parameters of the MLD. We proved that a reference prior for the shape parameter is a first-order probability matching prior, but the reference priors for the scale parameters do not satisfy the first-order matching criterion. In addition, a second-order probability matching prior does not exist for all parameters. We also presented the conditions that make the posterior distributions for the general prior, including the probability matching prior and reference priors, to be proper. In particular, Jeffreys' prior and probability matching priors for all parameters give proper posteriors, whereas reference priors for scale parameters give improper posteriors. | Kang, Sang Gil; Lee, Woo Dong; Kim, Yongku | Sangji Univ, Dept Comp & Data Informat, Wonju, South Korea; Daegu Haany Univ, Premajor Cosmet & Pharmaceut, Gyongsan, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu 41566, South Korea | 56119861400; 8328822200; 47962102500 | kim.1252@knu.ac.kr; | COMMUNICATIONS IN STATISTICS-THEORY AND METHODS | COMMUN STAT-THEOR M | 0361-0926 | 1532-415X | 53 | 7 | SCIE | STATISTICS & PROBABILITY | 2024 | 0.8 | 71.6 | 0 | 2025-04-16 | 0 | 0 | Matching prior; multivariate Lomax distribution; objective Bayesian inference; reference prior | IMPROVED ESTIMATORS; SCALE PARAMETER; MIXTURE; MODEL | Matching prior; multivariate Lomax distribution; objective Bayesian inference; reference prior | Inference engines; Probability distributions; Bayesian inference; First order; Lomax distribution; Matching prior; Matchings; Multivariate lomax distribution; Objective bayesian inference; Probability matching; Reference prior; Scale parameter; Bayesian networks | English | 2024 | 2024-04-02 | 10.1080/03610926.2022.2126945 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Bootstrap confidence interval estimation in generalized nonlinear models | The excess relative risk (ERR) model is a statistical model commonly used in radiation epidemiology to estimate the increased risk of cancer associated with radiation exposure. Generally, the parameters of the ERR model are estimated using the maximum likelihood estimation in generalized nonlinear models (GNMs) with a log-linear link function. One of the key challenges in applying GNMs is the evaluation of model uncertainty. We investigated likelihood-based approaches (Wald and profile likelihood methods) and various bootstrap confidence interval estimation methods to evaluate the statistical uncertainty of the model parameter estimators. In addition, we compared nonparametric and parametric resampling techniques in a GNM setting. Numerical studies were conducted on the normal, Poisson, and Bernoulli random variables of the responses given covariates. We applied the proposed methods to the ERR models used in the Life Span Study at the Radiation Effects Research Foundation and the Korean diagnostic medical radiation workers cohort. © 2024 Taylor & Francis Group, LLC. | Jeong, Haesu; Kim, Young Min; Bang, Ye Jin; Seo, Songwon; Lee, Won Jin | Laboratory of Radiation Health Assessment, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea, Department of Public Health, Korea University Graduate School, Seoul, South Korea; Department of Statistics, Kyungpook National University, Daegu, South Korea; Department of Preventive Medicine, Korea University College of Medicine, Seoul, South Korea; Laboratory of Radiation Health Assessment, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea; Department of Preventive Medicine, Korea University College of Medicine, Seoul, South Korea | 58995213700; 56035273800; 56985424800; 36667300100; 55641918400 | kymmyself@knu.ac.kr; | Communications in Statistics: Simulation and Computation | COMMUN STAT-SIMUL C | 0361-0918 | 1532-4141 | SCIE | STATISTICS & PROBABILITY | 2024 | 0.8 | 71.6 | 0 | 2025-04-16 | 1 | Bootstrap; Confidence interval; Generalized nonlinear models; Nonparametric; Parametric | Diagnosis; Nonlinear analysis; Nonlinear systems; Parameter estimation; Radiation effects; Risk perception; Uncertainty analysis; Bootstrap; Bootstrap confidence interval; Confidence interval; Confidence interval estimation; Excess relative risk models; Generalised non-linear models; Nonparametrics; Parametric; Radiation Exposure; Statistic modeling; Maximum likelihood estimation | English | Article in press | 2024 | 10.1080/03610918.2024.2344708 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Objective Bayesian analysis of the ratio of bivariate lognormal means | In this study, we consider the objective Bayesian analysis for the ratio of means in the bivariate lognormal distribution, in which properly assigning priors for the ratio of means is challenging due to the presence of nuisance parameters. As a result, we create probability matching priors and reference priors for the ratio of means. Jeffreys' prior and the two group reference prior do not satisfy a first-order matching criterion. We also investigate the posterior distribution property for the general prior class, which includes Jeffreys' prior, the reference prior, and the matching prior. Through a simulation study, we check the frequentist coverage probabilities and compare them with the generalized confidence interval method. It demonstrated that the proposed probability matching priors match very well with the target coverage probabilities even when the sample sizes are small in a frequentist sense. Two real examples are also provided. | Kang, Sang Gil; Lee, Woo Dong; Kim, Yongku | Sangji Univ, Dept Comp & Data Informat, Wonju, South Korea; Daegu Haany Univ, Premajor Cosmet & Pharmaceut, Gyongsan, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea | 56119861400; 8328822200; 47962102500 | kim.1252@knu.ac.kr; | COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION | COMMUN STAT-SIMUL C | 0361-0918 | 1532-4141 | 53 | 10 | SCIE | STATISTICS & PROBABILITY | 2024 | 0.8 | 71.6 | 0 | 2025-04-16 | 0 | 0 | Bayesian inference; Bivariate lognormal distribution; Matching prior; Ratio of means; Reference prior | FREQUENTIST VALIDITY; SIZE DISTRIBUTIONS; PARAMETER; PRIORS | Bayesian inference; Bivariate lognormal distribution; Matching prior; Ratio of means; Reference prior | Bayesian networks; Codes (symbols); Bayesian Analysis; Bayesian inference; Bivariate; Bivariate lognormal distribution; Log-normal distribution; Matching prior; Matchings; Probability matching; Ratio of mean; Reference prior; Inference engines | English | 2024 | 2024-10-02 | 10.1080/03610918.2022.2155309 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Objective Bayesian multiple testing for k normal populations | This article proposes objective Bayesian multiple testing procedures for a normal model. The challenging task of considering all the configurations of true and false null hypotheses is addressed here by ordering the null hypotheses based on their Bayes factors. This approach reduces the size of the compared models for posterior search from 2(k) to k + 1 , for k null hypotheses. Furthermore, the consistency of the proposed multiple testing procedures is established and their behavior is analyzed with simulated and real examples. In addition, the proposed procedures are compared with classical and Bayesian multiple testing procedures in all the possible configurations of true and false ordered null hypotheses. | Kang, Sang Gil; Kim, Yongku | Sangji Univ, Dept Comp & Data Informat, Wonju 26339, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Basic Sci, KNU G LAMP Res Ctr, Daegu 41566, South Korea | 56119861400; 47962102500 | kim.1252@knu.ac.kr; | JOURNAL OF THE KOREAN STATISTICAL SOCIETY | J KOREAN STAT SOC | 1226-3192 | 2005-2863 | 53 | 4 | SCIE | STATISTICS & PROBABILITY | 2024 | 0.8 | 71.6 | 0 | 2025-05-07 | 0 | 0 | Bayes factor; Intrinsic prior; Model selection; Multiple hypothesis testing | FALSE DISCOVERY RATE; MODEL SELECTION; EMPIRICAL BAYES | Bayes factor; Intrinsic prior; Model selection; Multiple hypothesis testing | English | 2024 | 2024-12 | 10.1007/s42952-024-00281-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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