연구성과로 돌아가기
2023 연구성과 (224 / 285)
※ 컨트롤 + 클릭으로 열별 다중 정렬 가능합니다.
Excel 다운로드
| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ○ | ○ | Article | Vaginal Infections during Pregnancy Increase Breast Milk Microbiome Alpha Diversity and Alter Taxonomic Composition | We previously reported that breast milk from women with (W) or without (WO) vaginal yeast infection during pregnancy differs in its immunological and antimicrobial properties, especially against pathogenic vaginal Candida sp.. Here, we investigated the differences in microbiota profiles of breast milk from these groups. Seventy-two breast milk samples were collected from lactating mothers (W, n=37; WO, n=35). The DNA of bacteria was extracted from each breast milk sample for microbiota profiling by 16S rRNA gene sequencing. Breast milk from the W-group exhibited higher alpha diversity than that from the WO-group across different taxonomic levels of class (P=0.015), order (P=0.011), family (P=0.020), and genus (P=0.030). Compositional differences between groups as determined via beta diversity showed marginal differences at taxonomic levels of phylum (P=0.087), family (P=0.064), and genus (P=0.067). The W-group showed higher abundances of families Moraxellaceae (P=0.010) and Xanthomonadaceae (P=0.008), and their genera Acinetobacter (P=0.015), Enhydrobacter (P=0.015), and Stenotrophomonas (P=0.007). Meanwhile, the WO-group showed higher abundances of genus Staphylococcus (P=0.046) and species Streptococcus infantis (P=0.025). This study shows that, although breast milk composition is affected by vaginal infection during pregnancy, this may not pose a threat to infant growth and development. | Nisaa, Azka Ainun; Oon, Chern-Ein; Sreenivasan, Sasidharan; Balakrishnan, Venugopal; Rajendran, Deepa; Tan, Jun-Jie; Roslan, Fatin Fazrina; Todorov, Svetoslav Dimitrov; Jeong, Woo-Sik; Zhao, Feiyan; Nasir, Nur Syafiqah Mohamad; Deris, Zakuan Zainy; Zhang, Heping; Park, Yong-Ha; Liu, Guoxia; Liong, Min-Tze | Univ Sains Malaysia, Bioproc Technol Div, Sch Ind Technol, Gelugor 11800, Penang, Malaysia; Univ Sains Malaysia, Inst Res Mol Med INFORMM, Gelugor 11800, Penang, Malaysia; Univ Sains Malaysia, Adv Med & Dent Inst, Gelugor 13200, Penang, Malaysia; Univ Sao Paulo, Fac Pharmaceut Sci, Dept Food Sci & Expt Nutr, ProBacLab, BR-05508090 Sao Paulo, Brazil; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Funct Food Chem Lab, Daegu 37224, South Korea; Inner Mongolia Agr Univ, Key Lab Dairy Biotechnol & Engn, Minist Educ, Hohhot 010018, Inner Mongolia, Peoples R China; Hosp Univ Sains Malaysia, Sch Med Sci, Dept Clin Microbiol, Med Microbiol Lab, Kota Baharu 16150, Kelantan, Malaysia; Probionic Corp, Gyongsan 54576, Jeonbuk, South Korea; Chinese Acad Sci, Inst Microbiol, CAS Key Lab Microbial Physiol & Metab Engn, State Key Lab Microbial Resources, Beijing 100864, Peoples R China; CAS TWAS Ctr Excellence Biotechnol, Beijing 100101, Peoples R China; Univ Sains Malaysia, Sch Ind Technol, Renewable Biomass Transformat Cluster, Gelugor, Penang 11800, Malaysia | Jeong, Woo-Sik/AAN-6885-2020; Zhao, Fei-yan/AAP-7791-2020; Dimitrov Todorov, Svetoslav/JVO-6224-2024; TAN, JUN JIE/D-9864-2012; Liong, Min-Tze/GVT-7267-2022; Balakrishnan, Venugopal/E-4774-2012; Oon, Chern/B-3684-2013; Tan, Jun/D-9864-2012; Deris, Zakuan/F-1264-2013; Sasidharan, Sreenivasan/A-6913-2011 | 57699913100; 36604977400; 15822788800; 55147166500; 58283859400; 51261516300; 57206257748; 7005217476; 10440750200; 57194507766; 57224368659; 23979654900; 57192488467; 59847092200; 23389647900; 22035883200 | liuguoxia@im.ac.cn;mintze.liong@usm.my; | PREVENTIVE NUTRITION AND FOOD SCIENCE | PREV NUTR FOOD SCI | 2287-1098 | 2287-8602 | 28 | 1 | ESCI | FOOD SCIENCE & TECHNOLOGY;NUTRITION & DIETETICS | 2023 | 1.6 | 72.5 | 0.83 | 2025-06-25 | 5 | 5 | breast milk; microbial community composition; microbiota; vaginal yeast infection | breast milk; microbial community composition; microbiota; vaginal yeast infection | English | 2023 | 2023-03 | 10.3746/pnf.2023.28.1.1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Genome editing (CRISPR/Cas9) in plant disease management: challenges and future prospects | The field of plant pathology has adopted targeted genome editing technology as one of its most crucial and effective genetic tools. Due to its simplicity, effectiveness, versatility, CRISPR together with CRISPR-associated proteins found in an adaptive immune system of prokaryotes have recently attracted the interest of the scientific world. Plant disease re-sistance must be genetically improved for sustainable agriculture. Plant biology and bio-technology have been transformed by genome editing, which makes it possible to perform precise and targeted genome modifications. Editing offers a fresh approach by genetically enhancing plant disease resistance and quickening resistance through breeding. It is sim-pler to plan and implement, has a greater success rate, is more adaptable and less expensive than other genome editing methods. Importantly CRISPR/Cas9 has recently surpassed plant science as well as plant disease. After years of research, scientists are currently modi-fying and rewriting genomes to create crop plants which are immune to particular pests and diseases. The main topics of this review are current developments in plant protection using CRISPR/Cas9 technology in model plants and commodities in response to viral, fun-gal, and bacterial infections, as well as potential applications and difficulties of numerous promising CRISPR/Cas9-adapted approaches. | Das, Kallol; Ayim, Benjamin Yaw; Borodynko-Filas, Natasza; Das, Srijan Chandra; Aminuzzaman, F. M. | Kyungpook Natl Univ, Coll Agr & Life Sci, Daegu 41566, South Korea; Plant Protect & Regulatory Serv Directorate, Minist Food & Agr, Ashanti, Ghana; Natl Res Inst, Inst Plant Protect, Plant Dis Clin & Bank Pathogens, Poznan, Poland; Bangladesh Rice Res Inst, Rice Farming Syst Div, Reg Stn, Gopalganj, Bangladesh; Sher Ebangla Agr Univ, Dept Plant Pathol, Sher Ebangla Nagar, Dhaka 1207, Bangladesh | Natasza, Borodynko-Filas/AAP-3321-2021; Das, Kallol/AAR-6707-2020 | 57203751520; 57210220749; 57216886719; 58597527700; 16232251100 | kalloldas91@gmail.com; | JOURNAL OF PLANT PROTECTION RESEARCH | J PLANT PROTECT RES | 1427-4345 | 1899-007X | 63 | 2 | ESCI | AGRONOMY;PLANT SCIENCES | 2023 | 0.7 | 72.6 | 0.33 | 2025-06-25 | 6 | 6 | CRISPR; Cas9; genome editing; plant disease management; plant-pathogen interaction | GUIDED SURVEILLANCE COMPLEX; SUSCEPTIBILITY GENE; CRYSTAL-STRUCTURE; RNA; RESISTANCE; SYSTEM; RICE; CLASSIFICATION; REPLICATION; RECOGNITION | CRISPR/Cas9; genome editing; plant disease management; plant-pathogen interaction | biotechnology; disease resistance; future prospect; genetic engineering; genome; host-pathogen interaction; immune system; pathology | English | 2023 | 2023 | 10.24425/jppr.2023.145761 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Harnessing the future: cutting-edge technologies for plant disease control | The world population is projected to reach 9.8 billion in 2050, and 11.2 billion in 2100 (United Nations) and people will need food, and decrease the farming land. Thus, the importance of Internet of Things (IoT) and Computer Science (CS) in plant disease management are increasing now-a-days. Mobile apps, remote sensing, spectral signature analysis, artificial neural networks (ANN), and deep learning monitors are commonly used in plant disease and pest management. IoT improves crop yield by fostering new farming methods along with the improvement of monitoring and management through cloud computing. In the quest for effective plant disease control, the future lies in cutting-edge technologies. The integration of IoT, artificial intelligence, and data analytics revolutionizes monitoring and diagnosis, enabling timely and precise interventions. Cloud computing facilitates real-time data sharing and analysis empower farmers to combat diseases with unprecedented efficiency. By harnessing these innovations, agriculture can embrace sustainable practices and safeguard crop health, ensuring a bountiful and secure future for the global food supply. | Rani, Suborna; Das, Kallol; Aminuzzaman, F. M.; Ayim, Benjamin Yaw; Borodynko-Filas, Natasza | Patuakhali Sci & Technol Univ, Fac Comp Sci & Engn, Patuakhali, Bangladesh; Kyungpook Natl Univ, Coll Agr & Life Sci, Daegu, South Korea; Sher E Bangla Agr Univ, Dept Plant Pathol, Dhaka, Bangladesh; Minist Food & Agr, Plant Protect & Regulatory Serv Directorate, Ashanti 23321, Ghana; Natl Res Inst, Inst Plant Protect, Plant Dis Clin, Poznan, Poland; Natl Res Inst, Inst Plant Protect, Bank Pathogens, Poznan, Poland | Das, Kallol/AAR-6707-2020; Natasza, Borodynko-Filas/AAP-3321-2021 | 57827333800; 57203751520; 16232251100; 57210220749; 57216886719 | kalloldas91@gmail.com; | JOURNAL OF PLANT PROTECTION RESEARCH | J PLANT PROTECT RES | 1427-4345 | 1899-007X | 63 | 4 | ESCI | AGRONOMY;PLANT SCIENCES | 2023 | 0.7 | 72.6 | 0.5 | 2025-06-25 | 5 | 9 | agriculture; computer science; crop protection; IoT; plant diseases | WHEAT; CLASSIFICATION; IDENTIFICATION; AGRICULTURE; ALGORITHMS; MANAGEMENT; SENSORS; IMAGERY; SYSTEM; RUST | agriculture; computer science; crop protection; IoT; plant diseases | agricultural land; artificial intelligence; computer simulation; crop yield; disease control; future prospect; Internet; precision | English | 2023 | 2023 | 10.24425/jppr.2023.147829 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical evaluation of a fluoroscopic image-based laser guidance system in bone tumor surgery: A technical note | This study presents a laser guidance system developed to enhance surgical accuracy and reduce radiation exposure in orthopedic surgeries. The system can project the actual position corresponding to the appointed position selected by the surgeon on a fluoroscopic image using a line laser and has laser projection ability to mark the corresponding point using a line laser. The surgeon does not have to perform anatomical marker placement for calibration. Three patients with bone tumors underwent surgeries using the laser guidance system, and the projection accuracy was evaluated by measuring the distance error between the appointed and laser-marking positions. The installation time, including calibration, was also assessed for clinical usability. The average projection accuracy in bone tumor surgery was 2.86 mm, and the average installation time was 7 min. These results demonstrate that the laser guidance system, with a projection error of <3 mm, could be useful in bone tumor surgeries. | Bang, Hyunhee; Park, Chul Woo; Joung, Sanghyun; Lee, Hyun-Joo; Park, Il-Hyung | Kyungpook Natl Univ, Med Device & Robot Inst Pk, 1006 Global Pl, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthoped Surg, Dongduk Ro 130, Daegu 41944, South Korea | 57216785452; 23995581000; 14628748500; 58838750100; 35076285100 | lidmania@daum.net;ihpark@knu.ac.kr; | MEDICAL ENGINEERING & PHYSICS | MED ENG PHYS | 1350-4533 | 1873-4030 | 120 | SCIE | ENGINEERING, BIOMEDICAL | 2023 | 1.7 | 72.8 | 0 | 2025-06-25 | 0 | 0 | Laser guidance system; Fluoroscopic image; Bone tumor surgery; Tumor resection; Surgical navigation | NAVIGATION; RESECTION | Bone tumor surgery; Fluoroscopic image; Laser guidance system; Surgical navigation; Tumor resection | Bone Neoplasms; Bone Screws; Fluoroscopy; Humans; Lasers; Orthopedic Procedures; Surgery, Computer-Assisted; Laser surgery; Remote control; Transplantation (surgical); Tumors; Bone tumor; Bone tumor surgery; Clinical evaluation; Fluoroscopic images; Image-based; Installation time; Laser guidance systems; Surgical navigation; Technical notes; Tumor resection; accuracy; adult; Article; bone tumor; calibration; cancer surgery; child; clinical article; clinical evaluation; fluoroscopy; human; male; middle aged; orthopedic surgery; radiation exposure; school child; surgeon; usability; x-ray computed tomography; computer assisted surgery; diagnostic imaging; fluoroscopy; orthopedic surgery; procedures; Calibration | English | 2023 | 2023-10 | 10.1016/j.medengphy.2023.104056 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Cryogenic Temperatures Characterization of an MAPbBr3 Perovskite and a Silicon Photomultiplier for Radiation Detector Applications | Methylammonium lead bromide (MAPbBr(3)) perovskites are strong candidates for application as radiation detectors with both semiconducting and scintillating properties. The crystalline phase transition of MAPbBr(3) at cryogenic temperatures changes its electrical and optical properties. Herein, the optical and electrical properties of MAPbBr(3) are studied as a function of the decreasing temperature for cryogenic radiation detector applications. The optical properties are investigated by measuring the photoluminescence spectra excited using 310 and 410 nm light-emitting device, while the electrical properties are assessed by measuring the dark current and photocurrent. Furthermore, the premature breakdown voltage and gain of a silicon photomultiplier coupled with MAPbBr(3) as a photosensor are measured in relation to the temperature. | Jegal, Jin; Kim, Hongjoo; Park, HyeoungWoo | Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea | Kim, Hong Joo/AAE-1178-2022 | 57192238874; 59051568100; 58950744700 | hyeoung87@gmail.com; | PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS | PHYS STATUS SOLIDI B | 0370-1972 | 1521-3951 | 260 | 5 | SCIE | PHYSICS, CONDENSED MATTER | 2023 | 1.5 | 72.8 | 0.13 | 2025-06-25 | 0 | 1 | cryogenic temperatures; electrical characterization; optical characterization; perovskites; silicon photomultiplier | AVALANCHE PHOTODIODE; ROOM-TEMPERATURE; CSPBBR3 | cryogenic temperatures; electrical characterization; optical characterization; perovskites; silicon photomultiplier | Cryogenics; Lead compounds; Optical properties; Photoluminescence; Radiation detectors; Silicon; Cryogenic temperatures; Crystalline phase transition; Electrical and optical properties; Electrical characterization; Optical characterization; Scintillating properties; Semi-conducting property; Silicon photo multipliers (SiPM); Temperature changes; Temperature characterization; Perovskite | English | 2023 | 2023-05 | 10.1002/pssb.202200313 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Characterization of a conjugated polysuccinimide-carboplatin compound | Carboplatin, an advanced anticancer drug with excellent efficacy against ovarian cancer, was developed to alleviate the side effects that often occur with cisplatin and other platinum-based compounds. Our study reports the in vitro characteristics, viability, and activity of cells expressing the inducible nitric oxide synthase (iNOS) gene after carboplatin was conjugated with polysuccinimide (PSI) and administered in combination with other widely used anticancer drugs. PSI, which has promising properties as a drug delivery material, could provide a platform for prolonging carboplatin release, regulating its dosage, and improving its side effects. The iNOS gene has been shown to play an important role in both cancer cell survival and inhibition. Herein, we synthesized a PSI-carboplatin conjugate to create a modified anticancer agent and confirmed its successful conjugation. To ensure its solubility in water, we further modified the structure of the PSI-carboplatin conjugate with 2-aminoethanol groups. To validate its biological characteristics, the ovarian cancer cell line SKOV-3 and normal ovarian Chinese hamster ovary cells were treated with the PSI-carboplatin conjugate alone and in combination with paclitaxel and topotecan, both of which are used in conventional chemotherapy. Notably, PSI-carboplatin conjugation can be used to predict changes in the genes involved in cancer growth and inhibition. In conclusion, combination treatment with the newly synthesized polymer-carboplatin conjugate and paclitaxel displayed anticancer activity against ovarian cancer cells but was not toxic to normal ovarian cancer cells, resulting in the development of an effective candidate anticancer drug without severe side effects. | Lee, Sun Young; Chae, Chang Hoon; Zrinyi, Miklos; Che, Xiangguo; Choi, Je Yong; Cho, Dong-Hyu | Jeonbuk Natl Univ, Med Sch, Dept Radiat Oncol, Jeonju 54907, South Korea; Jeonbuk Natl Univ, Res Inst Clin Med, Biomed Res Inst, Jeonbuk Natl Univ Hosp, Jeonju 54907, South Korea; CELLDI Co Ltd, Cheongju 28160, South Korea; Semmelweis Univ, Dept Biophys & Radiat Biol, Lab Nanochem, H-1089 Budapest, Hungary; Kyungpook Natl Univ, Sch Med, Dept Biochem & Cell Biol, Daegu 41940, South Korea; Jeonbuk Natl Univ, Med Sch, Dept Obstet & Gynecol, Jeonju 54907, South Korea | Choi, Je-Yong/AAR-7334-2021 | 57203597345; 57202776427; 56223106600; 54792660600; 7501391068; 57194444220 | obgyn2001@jbnu.ac.kr; | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | KOREAN J PHYSIOL PHA | 1226-4512 | 2093-3827 | 27 | 1 | SCIE | PHARMACOLOGY & PHARMACY;PHYSIOLOGY | 2023 | 1.6 | 73.0 | 0 | 2025-06-25 | 0 | 0 | Carboplatin; Conjugation; Conjugation iNOS; Ovarian cancer; Polysuccinimide | ADVANCED OVARIAN-CANCER; NITRIC-OXIDE; DELIVERY-SYSTEMS; PACLITAXEL; APOPTOSIS; TOPOTECAN; CISPLATIN; POLYMERS; P53 | Carboplatin; Conjugation; iNOS; Ovarian cancer; Polysuccinimide | antineoplastic agent; carboplatin; inducible nitric oxide synthase; paclitaxel; polymer; polysuccinimide; topotecan; unclassified drug; animal cell; antineoplastic activity; Article; cancer growth; cell survival; CHO cell line; controlled study; drug conjugation; drug delivery system; drug solubility; drug synthesis; in vitro study; nonhuman; SK-OV-3 cell line; water solubility | English | 2023 | 2023-01 | 10.4196/kjpp.2023.27.1.31 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Curculigo konkanensis (Hypoxidaceae), a new species from the lateritic plateaus of Konkan region of Western Ghats based on morphological and molecular evidence | A new species Curculigo konkanensis, is described from the lateritic plateaus of the Konkan region of Maharashtra, India. The new species is allied with C. brevifolia and C. orchioides but differs in the characters of rootstock, height of plant, leaves, bracts, capsules and seeds. Cytological parameters, Karyotype formula, total haploid chromosome length (THCL), Value of CVCL and MCA also supported the distinctness of C. konkanensis, C. brevifolia and C. orchioides. Based on plastid DNA data, the new species is placed in Curculigo orchoides subclade and shows phylogenetic affinity with Curculigo brevifolia. | Borude, Devidas Bhausaheb; Tamboli, Asif Shabodin; Bhalekar, Paresh Pandharinath; Mane, Rohit Nivas; Choo, Yeon-Sik; Park, Jae Hong; Chandore, Arun Nivrutti | Sci Coll, Dept Bot, Abasaheb Marathe Arts & New Commerce, Rajapur 416702, Maharashtra, India; Kyungpook Natl Univ, Res Inst Dok Do & Ulleung Do Isl, Sch Life Sci, Dept Biol, 80 Daehak Ro, Daegu 41566, South Korea; Balawant Coll, Dept Bot, Vita 415311, Maharashtra, India; Kyungpook Natl Univ, Sch Life Sci, Dept Biol, 80 Daehak Ro, Daegu 41566, South Korea; Sci & Commerce Coll, Dept Bot Arts, Mokhada 401604, Maharashtra, India | Tamboli, Asif/HJB-2803-2022 | 57163574200; 56974034100; 58037814800; 57194283918; 26040458100; 7102232932; 34879363900 | devidasborude30@gmail.com;asift456@gmail.com;pareshbhalekar23@gmail.com;manerohit.suk@gmail.com;yschoo@knu.ac.kr;jhpak@knu.ac.kr;arunchandore@gmail.com; | PHYTOTAXA | PHYTOTAXA | 1179-3155 | 1179-3163 | 587 | 1 | SCIE | PLANT SCIENCES | 2023 | 1 | 73.0 | 0.2 | 2025-06-25 | 1 | 1 | Curculigo; cytology; lateritic plateaus; phylogeny; rbcL; Taxonomy; trnL-F; trnS-G | JANARTHANAMII HYPOXIDACEAE; MAHARASHTRA | Curculigo; cytology; lateritic plateaus; phylogeny; rbcL; Taxonomy; trnL-F; trnS-G | English | 2023 | 2023-03-09 | 10.11646/phytotaxa.587.1.1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Peptides derived from high voltage-gated calcium channel βsubunit reduce blood pressure in rats | The ss subunits of high voltage-gated calcium channels (HGCCs) are essential for optimal channel functions such as channel gating, activation-inactivation kinetics, and trafficking to the membrane. In this study, we report for the first time the potent blood pressure-reducing effects of peptide fragments derived from the ss subunits in anesthetized and non-anesthetized rats. Intravenous administration of 16- mer peptide fragments derived from the interacting regions of the ss 1 [cacb1(344-359)], ss 2 [ cacb2( 392- 407)], ss 3 [cacb3(292-307)], and ss 4 [cacb4( 333348)] subunits with the main a-subunit of HGCC decreased arterial blood pressure in a dose-dependent manner for 5-8 min in anesthetized rats. In contrast, the peptides had no effect on the peak amplitudes of voltage-activated Ca2+ current upon their intracellular application into the acutely isolated trigeminal ganglion neurons. Further, a single mutated peptide of cacb1(344-359)- cacb1(344-359)(K357R)-showed consistent and potent effects and was crippled by a two-amino acid-truncation at the Nterminal or C-terminal end. By conjugating palmitic acid with the second amino acid (lysine) of cacb1(344-359) K-357R (named K2-palm), we extended the blood pressure reduction to several hours without losing potency. This prolonged effect on the arterial blood pressure was also observed in non-anesthetized rats. On the other hand, the intrathecal administration of acetylated and amidated cacb1(344-359) K-357R peptide did not change acute nociceptive responses induced by the intradermal formalin injection in the plantar surface of rat hindpaw. Overall, these findings will be useful for developing antihypertensives. | Kim, Hyung Kyu; Jun, Jiyeon; Kim, Tae Wan; Youn, Dong-ho | Kyungpook Natl Univ, Sch Dent, Dept Oral Anat, Daegu 41940, South Korea; Kyungpook Natl Univ, Adv Dent Device Dev Inst, Sch Dent, Daegu 41940, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Physiol, Daegu 41566, South Korea | Kim, Hyung/J-5451-2012; Kim, Hyongbum/D-5804-2019 | 57208751988; 57219856577; 57202769925; 7005252239 | dyoun@knu.ac.kr; | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | KOREAN J PHYSIOL PHA | 1226-4512 | 2093-3827 | 27 | 5 | SCIE | PHARMACOLOGY & PHARMACY;PHYSIOLOGY | 2023 | 1.6 | 73.0 | 0 | 2025-06-25 | 0 | 0 | beta subunit; Blood pressure; High voltage-gated calcium channel; Pain; Trigeminal ganglion neurons | DELIVERY; COMPLEX; CASEIN | Blood pressure; High voltage-gated calcium channel; Pain; Trigeminal ganglion neurons; β subunit | amino acid; antihypertensive agent; calcium ion; formaldehyde; lysine; palmitic acid; peptide fragment; voltage gated calcium channel; alpha chain; amidation; amino terminal sequence; animal experiment; antihypertensive therapy; arterial pressure; Article; beta chain; blood pressure; blood pressure monitoring; carboxy terminal sequence; controlled study; hind paw; intravenous drug administration; male; nerve cell; nonhuman; pain; rat; trigeminus ganglion | English | 2023 | 2023-09 | 10.4196/kjpp.2023.27.5.481 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Rac1 inhibition protects the kidney against kidney ischemia/reperfusion through the inhibition of macrophage migration | Kidney ischemia/reper fusion (I/R) injury, a common cause of acute kidney injury (AKI), is associated with the migration of inflammatory cells into the kidney. Ras-related C3 botulinum toxin substrate 1 (Rac1), a member of the Rho family of small GTPase, plays an important role in inflammatory cell migration by cytoskeleton rearrangement. Here, we investigated the role of Rac1 on kidney I/R injury and macrophage migration. Male mice were subjected to either 25 min of bi-lateral ischemia followed by reperfusion (I/R) or a sham operation. Some mice were administrated with either NSC23766, an inhibitor of Rac1, or 0.9% NaCl (vehicle). Kidney damage and Rac1 activity and expression were measured. The migration and lamellipodia formation of RAW264.7 cells, mouse monocyte/macrophage, induced by monocyte chemoattractant protein-1 (MCP-1, a chemokine) were determined us-ing transwell migration assay and phalloidin staining, respectively. In sham-operated kidneys, Rac1 was expressed in tubular cells and interstitial cells. In I/R-injured kid-neys, Rac1 expression was decreased in tubule cells in correlation with the damage of tubular cells, whereas Rac1 expression increased in the interstitium in correlation with an increased population of F4/80 cells, monocytes/macrophages. I/R increased Rac1 activity without changing total Rac1 expression in the whole kidney lysates. NSC23766 administration blocked Rac1 activation and protected the kidney against I/R-induced kidney damage and interstitial F4/80 cell increase. NSC23766 suppressed monocyte MCP-1-induced lamellipodia and filopodia formation and migration of RAW 264.7 cells. These results indicate Rac1 inhibition protects the kidney against I/R via inhibition of monocytes/macrophages migration into the kidney. | Park, You Ri; Kong, Min Jung; Noh, Mi Ra; Park, Kwon Moo | Kyungpook Natl Univ, Grad Sch, Dept Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ, Grad Sch, BK21 Plus, Daegu 41944, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Anat, Daegu 41944, South Korea | 58251827200; 57194730911; 14421357000; 8785448200 | kmpark@knu.ac.kr; | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | KOREAN J PHYSIOL PHA | 1226-4512 | 2093-3827 | 27 | 3 | SCIE | PHARMACOLOGY & PHARMACY;PHYSIOLOGY | 2023 | 1.6 | 73.0 | 0.17 | 2025-06-25 | 1 | 1 | Acute kidney injury; Ischemia; Macrophages; Macrophage migration; Rac1-GTPase | RHO-GTPASES; INJURY; ACTIVATION; SUSCEPTIBILITY; PROLIFERATION; INFILTRATION; APOPTOSIS; ISCHEMIA; STRESS; CELLS | Acute kidney injury; Ischemia; Macrophage migration; Macrophages; Rac1-GTPase | 4 amino 6 [2 [[4 (diethylamino) 1 methylbutyl]amino] 6 methyl 4 pyrimidinyl] 2 methylquinoline; monocyte chemotactic protein 1; pentobarbital; phalloidin; Rac1 protein; sodium chloride; adult; animal cell; animal experiment; animal model; Article; cell lysate; cell migration; controlled study; correlational study; enzyme activity; filopodium; kidney injury; kidney interstitium; lamellipodium; Leydig cell; macrophage; macrophage migration inhibition; male; monocyte; mouse; nonhuman; protein expression; RAW 264.7 cell line; renal ischemia reperfusion injury; renal protection; sham procedure; staining; transwell assay | English | 2023 | 2023-05 | 10.4196/kjpp.2023.27.3.257 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A case of Fahr disease with transient slurred speech and abnormal movement of the left arm | Fahr disease is a rare neurological condition characterized by abnormal basal ganglia calcification. Some patients with Fahr disease have been reported to present to the emergency department (ED) with stroke-like symptoms. Here, we present a case of Fahr disease with transient focal neurological signs. A 63-year-old man came to the ED with complaints of slurred speech and abnormal movement of his left arm. His symptoms lasted only 5 minutes before he recovered. He had no focal neurological deficits when he arrived at the ED, had no previous medical history and had never taken any medication. A physical examination revealed that the patient was healthy, and the initial results of laboratory tests were all within normal range. A brain computed tomography (CT) without contrast enhancement revealed symmetric calcification of the basal ganglia, thalamus and dentate nucleus of the cerebellum. Magnetic resonance imaging of the brain and neck CT angiography revealed no evidence of acute cerebral infarction, intracranial large-vessel occlusion, or stenosis. Based on his clinical presentation and examination results, the patient was diagnosed with Fahr disease in the ED. He was recommended to be admitted for differential diagnosis of seizures and additional tests, such as electroencephalography, but opted for discharge against medical advice. Emergency physicians should consider the possibility of Fahr disease if patients have focal neurological signs with characteristic symmetric calcification on brain CT. A detailed history and examination should be performed to detect other secondary causes associated with Fahr syndrome. | Jung, Haewon; Ahn, Jae Yun; Cho, Jae Wan; Moon, Sungbae; Ryoo, Hyun Wook | Kyungpook Natl Univ, Sch Med, Dept Emergency Med, Daegu 41944, South Korea | Ahn, Jae Yun/N-2652-2017 | 57221554827; 56937505400; 7403536065; 57191584601; 55350557500 | jyahn@knu.ac.kr; | SIGNA VITAE | SIGNA VITAE | 1334-5605 | 1845-206X | 19 | 4 | SCIE | EMERGENCY MEDICINE | 2023 | 1 | 73.1 | 0 | 2025-06-25 | 0 | 0 | Fahr disease; Basal ganglia calcification; Computed tomography | CEREBRAL-BLOOD-FLOW | Basal ganglia calcification; Computed tomography; Fahr disease | ammonia; cholesterol; creatine kinase; lactic acid; myoglobin; potassium; sodium; adult; apparent diffusion coefficient; arm; Article; autonomic nervous system; basal ganglion; brain calcification; brain infarction; case report; cerebellum; clinical article; computed tomographic angiography; computer assisted tomography; dentate nucleus; differential diagnosis; diffusion weighted imaging; dysarthria; electrocardiogram; electroencephalography; emergency physician; emergency ward; Fahr disease; heart rate; hospital discharge; human; involuntary rhythmic movement; leukocyte count; male; middle aged; neuroimaging; neurologic disease; neurologic examination; neutrophil count; nuclear magnetic resonance imaging; platelet count; seizure; slurred speech; stenosis; thalamus; thalamus nucleus | English | 2023 | 2023-07 | 10.22514/sv.2023.066 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Multiple sinus pauses during suspension laryngoscopy with external laryngeal manipulation in hyperextended neck position in a patient with enlarged cervical lymph nodes: a case report | Suspension laryngoscopy is a commonly performed procedure for effective laryngeal microsurgery (LMS). Although it is associated with few adverse events, cardiac complications such as severe arrhythmia induced by exaggerated vagal tone may arise during this procedure. Here, I present the case of a 52-year-old female patient who presented with a suspected thyroid follicular neoplasm and enlarged cervical lymph nodes. LMS was planned to remove a vocal fold polyp before the thyroid surgery. The patient was placed in a Boyce-Jackson position, and suspension laryngoscopy was performed. However, several sinus pauses were detected whenever external laryngeal manipulation (ELM) was performed to improve surgical field exposure, which was presumed to be attributed to vagal stimulation or reflex induced by numerous external and internal factors during laryngeal manipulation. The suspected mechanism was the direct stimulation of the vagus nerve termed the laryngo-cardiac reflex, or carotid sinus reflex, a type of baroreceptor reflex. When the first episode of sinus pause occurred, the effect-site target concentration of propofol was unadjusted after checking the bispectral index level indicating an adequate anesthetic depth, but ELM was discontinued. When the second episode occurred, ELM could not be stopped until good laryngeal visualization was achieved. Then, the patient received 0.2 mg of intravenous glycopyrrolate. Her heart rate returned within the normal range whenever ELM was not applied. When performing suspension laryngoscopy, the head and neck positioning, the procedure itself and laryngeal manipulation may act as external factors that could induce an exaggerated vagal response. Further, patients with head and neck tumors have various internal factors, such as tumor itself, cervical lymphadenopathy or postirradiation fibrosis, which can affect the carotid sinus and deteriorate the vagal response. Therefore, careful preoperative evaluation is required to identify these internal factors in advance and take proper care to minimize the additional influence of external factors. | Byun, Sung-Hye | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Anesthesiol & Pain Med, Daegu 41404, South Korea | Byun, Sung Hye/AEK-1234-2022 | 56921446300 | stone0311@naver.com; | SIGNA VITAE | SIGNA VITAE | 1334-5605 | 1845-206X | 19 | 4 | SCIE | EMERGENCY MEDICINE | 2023 | 1 | 73.1 | 0.28 | 2025-06-25 | 3 | 1 | Suspension laryngoscopy; Head and neck cancer; Vagal stimulation; Vagal reflex; Sinus pause | HEAD; HYPERSENSITIVITY; MICROSURGERY | Head and neck cancer; Sinus pause; Suspension laryngoscopy; Vagal reflex; Vagal stimulation | C reactive protein; glycopyrronium; propofol; remifentanil; rocuronium; thyrotropin; thyroxine; adult; Article; bispectral index; blood pressure; bradycardia; carotid sinus pressoreceptor reflex; case report; cervical lymph node; cervical lymphadenopathy; clinical article; endotracheal intubation; female; fine needle aspiration biopsy; heart rate; human; laryngoscopy; lobectomy; lymphadenopathy; microsurgery; middle aged; multiple sinus; musculoskeletal system; neck; neck position; oxygen saturation; pressoreceptor reflex; pulse oximetry; thyroid function; thyroid surgery; thyroidectomy; vagus nerve | English | 2023 | 2023-07 | 10.22514/sv.2023.004 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | COMPARATIVE ASSESSMENT OF NUMERICAL TECHNIQUES FOR WEIBULL PARAMETERS’ ESTIMATION AND THE PERFORMANCE OF WIND ENERGY CONVERSION SYSTEMS IN NIGERIA | The wind speed of a location is a critical parameter for analyzing wind energy conversion systems. Background knowledge has revealed that the two-parameter Weibull distribution is commonly used for fitting wind speed data because of its simplicity, flexibility and suitability. This research study examines wind speed data from five locations in Nigeria (Kano, Maiduguri, Jos, Abuja and Akure). It employs five numerical techniques, namely the maximum likelihood method, method of moment, power density method, empirical method and the logarithmic moment method, to estimate the Weibull parameters based on the locations’ data. The goodness of fit test is used to determine which numerical method best fits the distribution. The paper also considers the techno-economic design of wind electricity of five 25 kW pitch-controlled wind turbines with dissimilar characteristics. The test result presents the method of moment and empirical method as the best methods for calculating the Weibull parameters. Results also show that wind turbine-3 has the least cost of energy and wind turbine-5 has the highest cost of energy. © 2023,IIUM Engineering Journal. All Rights Reserved. | Okakwu, Ignatius K.; Akinyele, Daniel O.; Olabode, Olakunle E.; Ajewole, Tituso.; Oluwasogo, Emmanuel S.; Oyedeji, Ajibola O. | Department of Electrical and Electronics Engineering, Olabisi Onabanjo University, Ago-Iwoye, Nigeria; Department of Electrical and Electronics Engineering, Olabisi Onabanjo University, Ago-Iwoye, Nigeria; Department of Electrical and Electronics Engineering, Osun State University, Osogbo, Nigeria; Department of Electrical and Electronics Engineering, Osun State University, Osogbo, Nigeria; School of Energy Engineering, Kyungpook National University, Daegu, South Korea; Department of Computer Engineering, Olabisi Onabanjo University, Ago-Iwoye, Nigeria | 57213353379; 56258883100; 57216846973; 56495605300; 57221907765; 57222746494 | oyedeji.ajibola@oouagoiwoye.edu.ng; | IIUM Engineering Journal | IIUM ENG J | 1511-788X | 2289-7860 | 24 | 1 | ESCI | ENGINEERING, MULTIDISCIPLINARY | 2023 | 0.6 | 73.2 | 1.2 | 2025-06-25 | 8 | Energy Cost 138; Numerical Method; Weibull Distribution; Wind Speed | English | Final | 2023 | 10.31436/iiumej.v24i1.2611 | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | Analysis of suicide statistics and trends between 2011 and 2021 among Korean women | Purpose: This study aims to analyze the number of suicide deaths in women, trends in suicide mortality, characteristics of suicide by age, and outcomes of suicide means over the past decade (2011-2021) in South Korea. Methods: Using cause of death data from Statistics Korea, an in-depth analysis of Korean women's suicide trends was conducted for the period of 2011-2021. Results: In 2021, women's suicide death in Korea was 4,159, a rate of 16.2 per 100,000 population. The rate increased by 1.4% from the previous year. Since 2011, women's suicide rate has been on a steady downward trend, but since 2018, it has been on the rise again. Suicide rates among women in their 20s and 30s have increased, especially since the coronavirus disease 2019 pandemic, and suicide rates among women over 70 years remain high. As compared to 2011, pesticide poisoning and hanging among the means of suicide have decreased significantly, while drug and carbon monoxide continue to increase. Conclusion: Suicide rates for Korean women in their 20s and 30s have increased significantly in recent years, and those for women over 70 years remain high. Therefore, it is necessary to investigate the causes and establish national policies for targeted management of these age groups, which contributes significantly to the rising suicide rate among Korean women. | Jang, Hyunjung; Lee, Seokmin; Park, Sanghee; Kang, Bobae; Choi, Hyunkyung | Catholic Kkottongnae Univ, Dept Nursing, Cheongju, South Korea; Stat Korea, Stat Res Inst, Daejeon, South Korea; Stat Korea, Vital Stat Div, Daejeon, South Korea; Kyungpook Natl Univ, Coll Nursing, 680 Gukchaebosangro, Daegu 41944, South Korea; Kyungpook Natl Univ, Res Inst Nursing Innovat, Daegu, South Korea | 57221038272; 57188690516; 57218675505; 57418672600; 55619940700 | hchoi@knu.ac.kr; | KOREAN JOURNAL OF WOMEN HEALTH NURSING | KOREAN J WOMEN HEALT | 2287-1640 | 2093-7695 | 29 | 4 | ESCI | NURSING | 2023 | 1 | 73.3 | 1.21 | 2025-06-25 | 3 | 4 | Mortality; Suicide; Women | Mortality; Suicide; Women | English | 2023 | 2023-12 | 10.4069/kjwhn.2023.12.14.1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Factors influencing maternal-fetal attachment in pregnant women during the COVID-19 pandemic: a cross-sectional study | Purpose: Coronavirus disease 2019 (COVID-19) has spread widely throughout the world, causing psychological problems such as fear, anxiety, and stress. During the COVID-19 pandemic, pregnant women have been concerned about both their own health and the health of their fetuses, and these concerns could negatively affect maternal-fetal attachment. Thus, this study aimed to explore the level of COVID-19 stress, resilience, and maternal-fetal attachment among pregnant women during the COVID-19 pandemic, and to identify factors influencing maternal-fetal attachment. Methods: In total, 118 pregnant women past 20 weeks gestation were recruited from two maternity clinics in Daegu, Korea, to participate in this descriptive correlational study during COVID-19. The factors influencing maternal-fetal attachment were analyzed using hierarchical multiple regression analysis. Results: The mean scores for COVID-19 stress, resilience, and maternal-fetal attachment were 57.18 +/- 10.32 out of 84, 67.32 +/- 15.09 out of 100, and 77.23 +/- 9.00 out of 96, respectively. Nulliparous pregnant women reported greater maternal-fetal attachment than multiparous pregnant women (p=.003). Religious pregnant women also reported greater maternal-fetal attachment than non-religious pregnant women (p=.039). Resilience (ss=.29, p=.002), COVID-19 stress (ss=.20, p=.030) and parity (ss=-.17, p=.047) were factors influencing maternal-fetal attachment, and these factors explained 26.4% of the variance in maternal-fetal attachment (F=10.12, p<.001). Conclusion: Converse to common sense, COVID-19 stress exerted a positive influence on maternal-fetal attachment in pregnant women during the COVID-19 pandemic. Healthcare providers need to recognize the positive influence of COVID-19 stress and implement intervention strategies to strengthen resilience in pregnant women to improve maternal-fetal attachment. | Yoon, Hyeryeong; Choi, Hyunkyung | Kyungpook Natl Univ, Coll Nursing, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Res Inst Nursing Sci, Daegu, South Korea | 58220444000; 55619940700 | hchoi@knu.ac.kr; | KOREAN JOURNAL OF WOMEN HEALTH NURSING | KOREAN J WOMEN HEALT | 2287-1640 | 2093-7695 | 29 | 1 | ESCI | NURSING | 2023 | 1 | 73.3 | 0.61 | 2025-06-25 | 2 | 2 | COVID-19; COVID-19 stress syndrome; Maternal-fetal relations; Pregnant women; Psychological resilience | PRENATAL STRESS | COVID-19; COVID-19 stress syndrome; Maternal-fetal relations; Pregnant women; Psychological resilience | Chinese | 2023 | 2023-03 | 10.4069/kjwhn.2023.02.21.3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Precise channel temperature prediction in AlGaN/GaN HEMTs via closed-form empirical expression | In this study, we introduced a closed-form empirical expression for estimating the channel temperature in AlGaN/GaN HEMTs. This model incorporates parameters such as substrate thickness, gate length, gate width, and temperature-dependent thermal conductivity. The model's validity was rigorously established through comprehensive comparisons involving the channel temperature measurement procedure (DC) and TCAD device simulations. The outcomes exhibited a noteworthy alignment with the observed model data, reinforcing its credibility. The model yields a notably improved accuracy in channel temperature estimation compared to assumptions based on constant thermal conductivity. This observation holds particular significance for GaN/ Sapphire HEMTs. The utilization of the closed-form expression enables the simultaneous optimization of both electrical and thermal properties, utilizing conventional computer-aided design tools. | Chakraborty, Surajit; Shin, Ju-Won; Amir, Walid; Shin, Ki-Yong; Hoshi, Takuya; Tsutsumi, Takuya; Sugiyama, Hiroki; Kim, Dae-Hyun; Kim, Tae-Woo | Univ Ulsan, Dept Elect Elect & Comp Engn, Ulsan, South Korea; NTT Corp, NTT Device Technol Labs, Kanagawa 2430198, Japan; Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea; Texas Tech Univ, Dept Elect & Comp Engn, Lubbock, TX 79409 USA | Kim, Junghwan/AAQ-9204-2021; Hoshi, Takuya/JRZ-1293-2023; Kim, Yong/H-6157-2013; Chakraborty, Surajit/IXD-2458-2023 | 57363002700; 57344071200; 57220184861; 57221120602; 36442190000; 37007126500; 35417698400; 57212363794; 57203495132 | dae-hyun.kim@ee.knu.ac.kr;twkim78@ulsan.ac.kr; | SOLID-STATE ELECTRONICS | SOLID STATE ELECTRON | 0038-1101 | 1879-2405 | 210 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED;PHYSICS, CONDENSED MATTER | 2023 | 1.4 | 73.5 | 0.13 | 2025-06-25 | 1 | 1 | AlGaN/GaN; Sapphire; Channel temperature; Modeling; TCAD simulation | THERMAL-RESISTANCE; MODEL | AlGaN/GaN; Channel temperature; Modeling; Sapphire; TCAD simulation | Aluminum gallium nitride; Electronic design automation; Gallium nitride; High electron mobility transistors; III-V semiconductors; Temperature measurement; Thermal conductivity; AlGaN/GaN; AlGaN/GaN HEMTs; AlGaN/GaN-HEMT; Channel temperature; Closed form; Empirical expression; Modeling; Substrate thickness; TCAD simulation; Temperature prediction; Sapphire | English | 2023 | 2023-12 | 10.1016/j.sse.2023.108788 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
페이지 이동: