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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Determination of Sufentanil in Human Plasma Using Ultra-high Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry (UPLC-MS/MS) Background Sufentanil, an opioid analgesic, is used as an induction agent for general anesthesia during surgery. Sufentanil is more active than other anesthetics and has a narrow therapeutic range. Therefore, a precise dosage regimen is necessary when administering sufentanil.Objective This study aimed to develop a bioanalytical method for the determination of sufentanil within the sensitive concentration range more than that in a previous study utilizing protein precipitation (PP) and determine the plasma concentration of sufentanil.Methods A method for quantitating sufentanil was developed using ultra-high performance liquid chromatography coupled with mass spectrometry (UPLC-MS/MS) and detection by electrospray ionization (ESI). The internal standard was sufentanil-d5. Chromatographic separation was performed using an Acquity UPLC HSS T3 column (50 x 2.1 mm, 1.8 mu m) from Waters (Milford, MA, USA). Protein precipitation (PP) was used for sample preparation, and gradient elution was conducted using a mobile phase consisting of 1 mL of 2M ammonium acetate in 99% formic acid in 1 L of water or in 1 L of acetonitrile. The total run time for the analysis was 5 min, and the flow rate was 0.4 mL/min.Results Standard curves were linear over ranges of 0.025-30 ng/mL for sufentanil with a correlation coefficient (r2) greater than 0.9998. The lower limit of quantification (LLOQ) was 0.025 ng/mL. The intra- and inter-day accuracies were 97.66%-108.8% and 101.25%-103.17%, respectively, and the precision did not exceed 15% for sufentanil.Conclusion This study developed a validated, simple, sensitive, and convenient UPLC-MS/MS method for quantifying sufentanil in human plasma. This method was applied to determine sufentanil concentration in the plasma of patients undergoing surgery. The bioanalytical method using PP showed a sufficiently sensitive concentration range. This method could be applied to various pharmacokinetic studies of sufentanil. Lee, Sang-Min; Kim, Suin; Shin, Dongseong; Shin, Kwang-Hee Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Coll Pharm, Daegu 41566, South Korea; Gachon Univ, Coll Med, Gil Med Ctr, Dept Clin Pharmacol & Therapeut, Seongnam, South Korea ; Lee, Sang-Jun/A-3892-2015 57213176293; 58772649700; 55384018800; 35216279300 kshin@knu.ac.kr; CURRENT ANALYTICAL CHEMISTRY CURR ANAL CHEM 1573-4110 1875-6727 19 7 SCIE CHEMISTRY, ANALYTICAL 2023 1.7 70.3 0.21 2025-06-25 1 2 Sufentanil; human plasma; bioanalysis; UPLC-MS/MS; protein precipitation (PP); MRM HUMAN SERUM; PHARMACOKINETICS bioanalysis; human plasma; MRM; protein precipitation (PP); Sufentanil; UPLC-MS/MS Electrospray ionization; High performance liquid chromatography; Mass spectrometry; Plasma (human); Proteins; Bioanalysis; Bioanalytical methods; Concentration ranges; Human plasmas; MRM; Protein precipitation; Sufentanil; Ultra-high performance liquid chromatographies; UPLC-MS/MS; Surgery English 2023 2023 10.2174/1573411019666230823094749 바로가기 바로가기 바로가기 바로가기
Article Illustrating the temperature and magnetic field effects on the magnetic hysteresis loops and specific absorption rate of superparamagnetic nanoparticles: new physical insights towards medical applications Starting from the magnetic Langevin equation and its associated Fokker-Planck equation, governing the reversal magnetization of single-domain ferromagnetic nanoparticles elucidated by Brown's model [W. F. Brown, Phys. Rev. 130 (1963) 1677; IEEE Trans. Mag. 15 (1979) 1196], the magnetic hysteresis loops and the specific absorption rate of nanoparticles with biaxial anisotropy are investigated. An illustration of the effect of the temperature and the applied magnetic field across a wide range of frequencies on both of the former quantities is revealed. Emerged new physical insights elucidated from the present study hold promise for realistic nanoscale medicinal applications and may pave the way for an accurate notable benefit of superparamagnetic nanoparticles having biaxial anisotropy in oncology. Rekik, Najeh; Ouari, Bachir; Lakshminarayana, G.; Alotaibi, Ahmed A.; Hussein, A. Wahab M. A.; Farooq, Umer; Nasri, Faouzi; Bentalha, Zine El-Abidine Univ Hail, Coll Sci, Phys Dept, Hail, Saudi Arabia; Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada; Univ Perpignan, Lab Math & Phys, Via Domitia, F-66860 Perpignan, France; Univ Tlemcen, Phys Dept, Rocade 2, Tilimsen 13000, Algeria; Kyungpook Natl Univ, Intelligent Construct Automat Ctr, 80 Daehak ro, Daegu 41566, South Korea; Univ Hail, Coll Sci, Dept Chem, Hail, Saudi Arabia; Ctr Energy, Lab Thermal Proc Res & Technol, Hammam Lif, Tunisia Farooq, Umer/AAY-8613-2021; Nasri, Faouzi/F-7409-2018; Rekik, Najeh/AAY-8625-2021; Faouzi, Nasri/F-7409-2018 22136167500; 8426899000; 57194637883; 57673638500; 57222516677; 58589294700; 55934171300; 56224374500 rekik@ualberta.ca;Bachir.Ouari@ac-montpellier.fr; EUROPEAN PHYSICAL JOURNAL B EUR PHYS J B 1434-6028 1434-6036 96 3 SCIE PHYSICS, CONDENSED MATTER 2023 1.6 70.3 0.13 2025-06-25 1 1 THERMAL FLUCTUATIONS Anisotropy; Fokker Planck equation; Hysteresis loops; Magnetic field effects; Magnetic materials; Medical applications; Nanomagnetics; Superparamagnetism; Biaxial anisotropy; Ferromagnetic nanoparticles; Fokker-Planck-equation; Langevin equation; Magnetic hysteresis loops; Magnetic-field effects; S models; Single domains; Specific absorption rate; Superparamagnetic nanoparticles; Magnetization reversal English 2023 2023-03 10.1140/epjb/s10051-023-00504-3 바로가기 바로가기 바로가기 바로가기
Article Selective inhibitory effects of suberosin on CYP1A2 in human liver microsomes Suberosin is a natural phytoconstituent isolated from Citropsis articulata, especially employed for its anticoagulant properties. Although metabolic studies assessing suberosin have been conducted, it is possible interactions with drugs and food have not yet been investigated. In the present study, we analyzed the selective inhibitory effects of suberosin on cytochrome P450 (CYP) enzymes using a cocktail probe assay. Various concentrations of suberosin (0-50 & mu;M) were incubated with isoform-specific CYP probes in human liver microsomes (HLMs). We found that suberosin significantly inhibited CYP1A2-catalyzed phenacetin O-deethylation, exhibiting IC50 values of 9.39 & PLUSMN; 2.05 and 3.07 & PLUSMN; 0.45 & mu;M with and without preincubation in the presence of & beta;-NADPH, respectively. Moreover, suberosin showed concentration-dependent, but not time-dependent, CYP1A2 inhibition in HLMs, indicating that suberosin acts as a substrate and reversible CYP1A2 inhibitor. Using a Lineweaver-Burk plot, we found that suberosin competitively inhibited CYP1A2-catalyzed phenacetin O-deethylation. Furthermore, suberosin showed similar inhibitory effects on recombinant human CYP1A1 and 1A2. In conclusion, suberosin may elicit herb-drug interactions by selectively inhibiting CYP1A2 during the concurrent administration of drugs that act as CYP1A2 substrates. Paudel, Sanjita; Jo, Hyoje; Lee, Taeho; Lee, Sangkyu Kyungpook Natl Univ, Coll Pharm, FOUR Community Based Intelligent Novel Drug Discov, Daegu, South Korea; Sungkyunkwan Univ, Sch Pharm, Suwon, South Korea; Sungkyunkwan Univ, Sch Pharm, Suwon 16419, South Korea; Kyungpook Natl Univy, Coll Pharm, FOUR Community Based Intelligent Novel Drug Discov, Daegu 41566, South Korea 57203320448; 58494527700; 57204032003; 57209046767 tlee@knu.ac.kr;sangkyu@skku.edu; BIOPHARMACEUTICS & DRUG DISPOSITION BIOPHARM DRUG DISPOS 0142-2782 1099-081X 44 5 SCIE PHARMACOLOGY & PHARMACY 2023 1.7 70.8 0 2025-06-25 0 0 competitive inhibition; human liver microsomes; reversible inhibitor; suberosin IN-VITRO; DRUG-INTERACTIONS; METABOLIC ENZYMES; PHARMACOKINETICS; MEDICINES; UTILITY; CYP2D6; PROBE competitive inhibition; CYP1A2; human liver microsomes; reversible inhibitor; suberosin Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; Phenacetin; cytochrome P450; cytochrome P450 1A; cytochrome P450 1A1; cytochrome P450 1A2; cytochrome P450 1A2 inhibitor; phenacetin; reduced nicotinamide adenine dinucleotide phosphate; CYP1A2 protein, human; cytochrome P450; cytochrome P450 1A2; cytochrome P450 inhibitor; phenacetin; suberosin; Article; catalysis; competitive inhibition; controlled study; herb drug interaction; human; IC50; liver microsome; metabolism English 2023 2023-10 10.1002/bdd.2370 바로가기 바로가기 바로가기 바로가기
Article Mitochondrial peroxiredoxin 5 overexpression suppresses insulin-induced adipogenesis by downregulating the phosphorylation of p38 Obesity is caused by the accumulation of excess lipids due to an energy imbalance. Differentiation of pre-adipocytes induces abnormal lipid accumulation, and reactive oxygen species (ROS) generated in this process promote the differentiation of pre-adipocytes through mitogen-activated protein kinase (MAPK) signaling. Peroxiredoxin (Prx) is a potent antioxidant enzyme, and peroxiredoxin 5 (Prx5), which is mainly expressed in cytosol and mitochondria, inhibits adipogenesis by regulating ROS levels. Based on previous findings, the present study was performed to investigate whether cytosolic Prx5 (CytPrx5) or mitochondrial Prx5 (MtPrx5) has a greater effect on the inhibition of adipogenesis. In this study, MtPrx5 decreased insulin-mediated ROS levels to reduce adipogenic gene expression and lipid accumulation more effectively than CytPrx5. In addition, we found that p38 MAPK mainly participates in adipogenesis. Furthermore, we verified that MtPrx5 overexpression suppressed the phosphorylation of p38 during adipogenesis. Thus, we suggest that MtPrx5 inhibits insulin-induced adipogenesis more effectively than CytPrx5. Shin, Hye Jin; Lee, Sung Woo; Kim, Mi Hye; Park, Young-Ho; Lee, Hong Jun; Lee, Dong-Seok Kyungpook Natl Univ, Sch Life Sci, KNU Creat Biores Grp BK21 4, Daegu, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Sch Life Sci & Biotechnol, Daegu, South Korea; Daegu Gyeongbuk Med Innovat Fdn DGMIF, New Drug Dev Ctr, Daegu, South Korea; Korea Res Inst Biosci & Biotechnol KRIBB, Futurist Anim Resource & Res Ctr FARRC, Cheongju, South Korea; Chungbuk Natl Univ, Coll Med, Cheongju, Chungbuk, South Korea; Chungbuk Natl Univ, Med Res Inst, Cheongju, Chungbuk, South Korea; HuMetaCELL Inc, Res Inst, Bucheon Si, Gyeonggi Do, South Korea lee, wj/JNR-4926-2023 58457027400; 57939888700; 57193994930; 56246852400; 35215736300; 57210068061 lee1@knu.ac.kr; BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY BIOSCI BIOTECH BIOCH 0916-8451 1347-6947 87 7 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY;CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY 2023 1.4 70.9 0.51 2025-06-25 2 2 3T3-L1 cells; adipogenesis; ROS; MAPK; peroxiredoxin 5 ACTIVATED PROTEIN-KINASE; ADIPOCYTE DIFFERENTIATION; OXIDATIVE STRESS; GLUCOSE-TRANSPORT; PPAR-GAMMA; OBESITY; DYSFUNCTION; EXPRESSION; INHIBITORS 3T3-L1 cells; adipogenesis; MAPK; peroxiredoxin 5; ROS 3T3-L1 Cells; Adipogenesis; Animals; Cell Differentiation; Insulin; Lipids; Mice; Mitochondria; Peroxiredoxins; Phosphorylation; Reactive Oxygen Species; Enzymes; Gene expression; Mitochondria; Phosphorylation; insulin; lipid; peroxiredoxin; reactive oxygen metabolite; 3t3-l1 cell; Adipocytes; Adipogenesis; Cytosolic; Energy imbalances; Lipid accumulations; Mitogen-activated protein kinase; Overexpressions; Peroxiredoxin 5; Reactive oxygen species; 3T3-L1 cell line; adipogenesis; animal; cell differentiation; genetics; metabolism; mitochondrion; mouse; phosphorylation; Insulin English 2023 2023-06-23 10.1093/bbb/zbad040 바로가기 바로가기 바로가기 바로가기
Article Morphological, phylogenetic and biogeographic characterizations of three heterotrophic nanoflagellates isolated from coastal areas of Korea Heterotrophic nanoflagellates (HNFs, 2-20 mu m in size) are important bacterivores in aquatic environments. We isolated and distinguished three HNF strains from Korean coastal samples: Ancyromonas kenti strain KM086, Cafeteria mylnikovii strain JS001 and Multimonas media strain JS004. Their 18S rDNA sequences aligned with previously known counterparts. Under light microscopy, all strains match their previous respective species descriptions. However, under scanning electron microscopy, strain JS004 shows some features at odds with prior observations of M. media, including different putative extrusomes, an 'unfrilled' skirt margin, and a putative 'tusk'. We also used the V4 region of 18S rDNA to study species distribution globally using Malaspina-2010 data from 122 surface stations and 13 various depth stations. Intriguingly, we found that A. kenti was most abundant in low-oxygen conditions of the bathypelagic zones (1000-4000 m deep) in the Pacific Ocean, suggesting a specialization for thriving in low-oxygen habitats. In contrast, we only found M. media represented at one surface site, and C. mylnikovii was not found at all. Thus, A. kenti may be one of the most important feeders on bacteria in the bathypelagic zones with low-oxygen concentrations, while the other two isolates appear to be rare species in marine systems. Jeong, Dong Hyuk; Lee, Hyeon Been; Heiss, Aaron A.; Cho, Byung Cheol; Park, Jong Soo Kyungpook Natl Univ, Dept Oceanog, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Inst Oceanog, Daegu, South Korea; Seoul Natl Univ, Sch Earth & Environm Sci, Seoul, South Korea; Kunsan Natl Univ, Saemangeum Environm Res Ctr, Kunsan, South Korea Heiss, Aaron/AAG-7269-2019; Park, Jong/AAJ-3576-2020 57338712200; 57337671100; 14068923500; 7401747485; 23486274100 jongsoopark@knu.ac.kr; MARINE BIOLOGY RESEARCH MAR BIOL RES 1745-1000 1745-1019 19 8-9 SCIE ECOLOGY;MARINE & FRESHWATER BIOLOGY 2023 1 71.0 0.22 2025-06-25 1 1 Classification; heterotrophic nanoflagellates; morphology; phylogenetic tree; global distribution pattern BICOSOECIDA; THECAMONAS; EVOLUTION; IDENTITY; WATERS; GENERA Classification; global distribution pattern; heterotrophic nanoflagellates; morphology; phylogenetic tree Korea; Pacific Ocean; biogeography; classification; coastal zone; flagellate; heterotrophy; isolated population; morphology; phylogenetics; rare species; specialization English 2023 2023-10-21 10.1080/17451000.2023.2271939 바로가기 바로가기 바로가기 바로가기
Article Effect of substitution of Dy³⁺ on dielectric constant and reliability of anti-ferroelectric PLZT The study aimed to investigate the impact of oxygen vacancies on the reliability of perovskite-structured ceramics. In particular, the focus was on anti-ferroelectric (PbLa)(ZrTi)O-3, commonly known as PLZT, which exhibits excellent DC-bias characteristics, making it a promising material for high-power capacitors. To address the issue of oxygen vacancies, Dy3+ was introduced as a donor by substituting it into (Pb0.82La0.12)(Zr0.86Ti0.14)O-3. As the substitution of Dy3+ increased, there was a decrease in the dielectric constant. However, this was accompanied by an increase in both breakdown voltage and reliability characteristics. Choi, Jeoung Sik; Kim, Dong Chul; Shin, Hyo Soon; Yeo, Dong Hun; Lee, Joon Hyung Korea Inst Ceram Engn & Technol, Nano Convergence Mat Ctr, 101 Sohoro, Jinju, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea 57478171200; 57226389154; 35273922400; 7006551146; 57204923460 hshin@kicet.re.kr; MRS COMMUNICATIONS MRS COMMUN 2159-6859 2159-6867 13 6 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY 2023 1.8 71.2 0 2025-06-25 0 0 Defects; Perovskites; Dy; Electrical properties DC ELECTRICAL DEGRADATION; PEROVSKITE-TYPE TITANATES; DEFECT CHEMISTRY; MICROSTRUCTURE; DYSPROSIUM; CERAMICS; MODEL Defects; Dy; Electrical properties; Perovskites Ferroelectricity; Oxygen vacancies; Reliability; Anti ferroelectrics; DC bias; Dy; Effect of substitution; High power capacitors; Reliability characteristics; Voltage characteristics; Perovskite English 2023 2023-12 10.1557/s43579-023-00443-1 바로가기 바로가기 바로가기 바로가기
Article Error bounds for ReLU networks with depth and width parameters Neural networks have shown high successful performance in a wide range of tasks, but further studies are needed to improve its performance. We construct the specific neural network architecture with a local connection which is universal approximator, and analyze its approximation error. This locally connected networks has higher application than one with the full connection because the locally connected network can be used to explain diverse neural networks such as CNNs. Our error estimate depends on two parameters: one controlling the depth of the hidden layer, and the other, the width of the hidden layers. Kang, Jae-Mo; Moon, Sunghwan Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea 56024930400; 56063426100 sunghwan.moon@knu.ac.kr; JAPAN JOURNAL OF INDUSTRIAL AND APPLIED MATHEMATICS JPN J IND APPL MATH 0916-7005 1868-937X 40 1 SCIE MATHEMATICS, APPLIED 2023 0.7 71.2 0 2025-06-25 0 0 Deep neural nets; ReLU network; Approximation theory; Cybenko DEEP; APPROXIMATION Approximation theory; Cybenko; Deep neural nets; ReLU network Error analysis; Network architecture; Connected networks; Cybenko; Deep neural nets; Error bound; Hidden layers; Local connections; Neural network architecture; Neural-networks; Performance; ReLU network; Deep neural networks English 2023 2023-01 10.1007/s13160-022-00515-0 바로가기 바로가기 바로가기 바로가기
Editorial Material Understanding of oral potentially malignant disorders and epithelial dysplasia among oral and maxillofacial surgeons Choi, So-Young Kyungpook Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, 2177 Dalgubeol Daero, Daegu 41940, South Korea 57202918688 dentalchoi@knu.ac.kr; JOURNAL OF THE KOREAN ASSOCIATION OF ORAL AND MAXILLOFACIAL SURGEONS J KOR ASSOC ORAL MAX 2234-7550 2234-5930 49 6 ESCI DENTISTRY, ORAL SURGERY & MEDICINE 2023 0.9 71.2 0.76 2025-06-25 1 1 actinic cheilitis; cancer susceptibility; cauterization; clinical outcome; cryosurgery; dental surgeon; Editorial; erythroleukoplakia; erythroplasia; follow up; human; intraepithelial neoplasia; laser surgery; medical society; nuclear size; oral leukoplakia; oral potentially malignant disorder; proliferative verrucous leukoplakia; smokeless tobacco; smoking English 2023 2023-12 10.5125/jkaoms.2023.49.6.309 바로가기 바로가기 바로가기 바로가기
Article 15-kV and 1.8-kJ/s High-Precision Capacitor Charging Power Supply Based on LCC Resonant Converter for Kicker Modulator System This article describes the development of a 15-kV and 1.8-kJ/s capacitor charging power supply (CCPS) for a kicker modulator system, which requires a high reproducibility of the charging voltage. The developed CCPS can achieve the high reproducibility by reducing a bucket size through the high-frequency operation of an LCC resonant converter. For the high-frequency switching, a gate driver circuit of silicon carbide (SiC) metal-oxide-semiconductor field effect transistors (MOSFETs) is proposed. To obtain a small parallel resonant capacitor, which is essential for the high-frequency operation, a resonant tank is implemented by applying multicore transformer structure. In addition, to reduce a voltage unbalance of the rectifier diodes, a complementary winding method is proposed. Furthermore, a burst mode control for flat-top voltage is presented. Experimental results of the developed CCPS are presented to verify the proposed works. © 1973-2012 IEEE. Kwon, Chang-Hyun; Bae, Jung-Soo; Kim, Tae-Hyun; Son, Seong-Ho; Jang, Sung-Roc; Yu, Chan-Hun; Ahn, Suk-Ho; Kim, Hyoung-Suk University of Science and Technology (UST), Department of Energy and Power Conversion Engineering, Daejeon, 34113, South Korea; Pohang Accelerator Laboratory (PAL), Pohang, 37673, South Korea; University of Science and Technology (UST), Department of Energy and Power Conversion Engineering, Daejeon, 34113, South Korea; University of Science and Technology (UST), Department of Energy and Power Conversion Engineering, Daejeon, 34113, South Korea; Korea Electrotechnology Research Institute (KERI), Electrophysics Research Center, Changwon, 51543, South Korea, University of Science and Technology (UST), Energy and Power Conversion Engineering, Daejeon, 34113, South Korea; Korea Electrotechnology Research Institute (KERI), Electrophysics Research Center, Changwon, 51543, South Korea, Kyungpook National University, School of Energy Engineering, Daegu, 41566, South Korea; Pohang Accelerator Laboratory (PAL), Pohang, 37673, South Korea; University of Science and Technology (UST), Department of Energy and Power Conversion Engineering, Daejeon, 34113, South Korea, Korea Electrotechnology Research Institute (KERI), Electrophysics Research Center, Changwon, 51543, South Korea 57825562900; 57195575347; 57219837559; 57219842388; 26422309700; 57190813654; 35788677400; 58740330300 khs@keri.re.kr; IEEE Transactions on Plasma Science IEEE T PLASMA SCI 0093-3813 1939-9375 51 10 SCIE PHYSICS, FLUIDS & PLASMAS 2023 1.3 71.3 0.72 2025-06-25 6 Capacitor charging power supply (CCPS); high precision; LCC resonant converter Electric rectifiers; MOSFET devices; Power quality; Rectifying circuits; Silicon carbide; Wide band gap semiconductors; Winding; Capacitor charging power supplies; Capacitor charging power supply; Charging voltage; High frequency operation; High reproducibility; High-precision; LCC resonant converter; Rectifier; Resonant converters; Transformer; Capacitance English Final 2023 10.1109/tps.2023.3290968 바로가기 바로가기 바로가기
Article Development of 120 kV and 60 kW Three Phase LCC Resonant Converter for Electron Beam Welding System This article describes the development of a 120 kV and 60 kW cathode power supply (CPS) for an electron beam welding (EBW) system. Since the developed CPS is based on a three phase LCC resonant converter, it shows many superior features such as parasitic component utilization and low output voltage ripple. In addition, by adopting a symmetrical bipolar voltage multiplier (SBVM) as the CPS rectifier, the voltage imbalance among SBVM stages can be reduced even at the high output current. Therefore, the CPS can effectively achieve the output voltage of 120 kV and output power of 60 kW with low voltage stress on SBVM components. Furthermore, by using phase shift modulation (PSM) for load regulation, the conduction and switching losses are reduced in the light load operation due to the fixed operating frequency and small circulating current compared with the conventional pulse frequency modulation (PFM). For the practical use of the three phase LCC resonant converter with SBVM, several issues about the implementations of the transformer and interleaved PSM controller are addressed. The developed CPS is installed on the 120 kV and 60 kW EBW systems and the experimental results are presented to verify the performance of the developed CPS. Son, Seong-Ho; Kwon, Chang-Hyun; Kim, Tae-Hyun; Yu, Chan-Hun; Jang, Sung-Roc; Han, Seong-Tae; Kim, Jong-Soo; Cho, Chu-Hyun; Kim, Hyoung-Suk Univ Sci & Technol UST, Dept Energy & Power Convers Engn, Daejeon 34113, South Korea; Korea Electrotechnol Res Inst KERI, Electrophys Res Ctr, Chang Won 51543, South Korea; Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea; Univ Sci & Technol UST, Dept Energy & Power Convers Engn, Daejeon 34113, South Korea Shon, Seongho/LOI-5826-2024; Kim, Tae/C-5935-2015; Kim, Tae/AAV-5521-2020 57219842388; 57825562900; 57219837559; 57190813654; 26422309700; 7405946474; 55985992500; 7403095598; 58740330300 shson95@keri.re.kr;kch5725@keri.re.kr;appleigig@keri.re.kr;chyu@keri.re.kr;scion10@keri.re.kr;saiph@keri.re.kr;jskim@keri.re.kr;cho@keri.re.kr;khs@keri.re.kr; IEEE TRANSACTIONS ON PLASMA SCIENCE IEEE T PLASMA SCI 0093-3813 1939-9375 51 10 SCIE PHYSICS, FLUIDS & PLASMAS 2023 1.3 71.3 1.01 2025-06-25 7 7 Electron beam applications; power supplies; voltage multipliers LCC RESONANT CONVERTER; BREAKDOWN CHARACTERISTICS; DESIGN Electron beam applications; power supplies; voltage multipliers Electric loads; Electric rectifiers; Electron beam welding; Power converters; Power quality; Bipolar voltages; Electron beam applications; Electron-beam welding; LCC resonant converter; Phase shift modulation; Power supply; Three phase; Three phasis; Voltage multipliers; Welding systems; Electron beams English 2023 2023-10 10.1109/tps.2023.3288116 바로가기 바로가기 바로가기 바로가기
Article The global financial crisis and protectionism: Substitution from tariffs to non-tariff measures This study empirically investigates the relationships between tariffs and non-tariff measures before and after the global financial crisis (GFC). The panel analysis is based on traded products of 70 countries from 1997 to 2015. For developed countries, we find that tariffs and non-tariff measures were complementary before the crisis, but they became substitutional afterward. We do not find such shift for developing countries. We also run the analysis by income levels and by types of products and observe differential effects of the GFC on the relationship between the two trade policies. Heo, Inae; Choi, Bo-Young Kyungpook Natl Univ, Dept Int Trade, Daegu, South Korea; Kyungpook Natl Univ, Sch Econ & Trade, Daegu, South Korea; Kyungpook Natl Univ, Sch Econ &Trade, 80 Daehak Ro, Daegu 41566, South Korea 58066196200; 57226503191 bychoi2@knu.ac.kr; BULLETIN OF ECONOMIC RESEARCH B ECON RES 0307-3378 1467-8586 75 4 SSCI ECONOMICS 2023 0.8 71.3 0.29 2025-06-25 1 2 global financial crisis; non-tariff measures; protectionism; tariffs PANEL-DATA; TRADE; RESTRICTIVENESS global financial crisis; non-tariff measures; protectionism; tariffs developing world; empirical analysis; financial crisis; global trade; protectionism; tariff structure; trade policy English 2023 2023-10 10.1111/boer.12386 바로가기 바로가기 바로가기 바로가기
Article Arrested Pneumatization of the Sphenoid Sinus The sphenoid bone is a complex structure in terms of its embryological origin. At birth, the sphenoid sinus is nonpneumatized. Arrested pneumatization of the sphenoid sinus is considered a normal anatomic variant but may be mistaken for disease in imaging studies. We report 2 cases of arrested pneumatization of the sphenoid sinus, a normal variant commonly misdiagnosed as a serious disease of the skull base. A 29-year-old man with a complaint of dizziness visited a local clinic for assessment. Computed tomography (CT) of the paranasal sinuses (PNS) showed a noneroding, nonexpansile, and nonhomogenous lesion in the sphenoid bone. Magnetic resonance imaging (MRI) of the brain revealed a high-signal lesion on both T1-weighted and T2-weighted images. Given these typical findings in the CT of PNS and MRI of the brain, the lesion was diagnosed as arrested pneumatization of the sphenoid sinus. In the second case, a 60-year-old woman with a complaint of headache visited a local clinic for assessment. CT of PNS showed a fibro-osseous lesion (with features of sclerosis and osteolysis) in the skull base. Brain MRI revealed a low-signal lesion on a T1-weighted image containing a high-signal intensity around the sphenoid bone, thereby suggesting internal fat contents. A precise interpretation of CT of PNS and brain MRI is essential to distinguish arrested pneumatization of the sphenoid sinus and to help establish a differential diagnosis and avoid needless biopsy. Cho, Hyung Joon; Hahm, Myong Hun; Kim, Jung Soo; Heo, Sung Jae Kyungpook Natl Univ, Dept Otorhinolaryngol Head & Neck Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Otorhinolaryngol Head & Neck Surg, 807 Hoguk Ro, Daegu 41404, South Korea 허, 성재/AAU-3921-2020 57219109483; 56015548700; 55720132500; 55822906000 hjjo0618@naver.com;entnose@kakao.com;profsookim@gmail.com;blueskyhsj@hanmail.net; JOURNAL OF CRANIOFACIAL SURGERY J CRANIOFAC SURG 1049-2275 1536-3732 34 3 SCIE SURGERY 2023 1 71.4 0 2025-06-25 1 0 sphenoid sinus; skull base; diagnosis diagnosis; skull base; sphenoid sinus Adult; Female; Heart Arrest; Humans; Infant, Newborn; Magnetic Resonance Imaging; Male; Middle Aged; Paranasal Sinuses; Skull Base; Sphenoid Bone; Sphenoid Sinus; Tomography, X-Ray Computed; adult; case report; diagnostic imaging; female; heart arrest; human; male; middle aged; newborn; nuclear magnetic resonance imaging; paranasal sinus; pathology; procedures; skull base; sphenoid; sphenoid sinus; x-ray computed tomography English 2023 2023-05 10.1097/scs.0000000000009097 바로가기 바로가기 바로가기 바로가기
Article Facial Asymmetry Phenotypes in Adult Patients With Unilateral Cleft Lip and Palate and Skeletal Class III Malocclusion Using Principal Component Analysis and Cluster Analysis The purpose of this study was to classify and characterize facial asymmetry (FA) phenotypes in adult patients with unilateral cleft lip and palate (UCLP) and skeletal class III malocclusion. The samples comprised 52 adult UCLP patients (36 men and 16 women; mean age, 22.43 y) who had undergone orthognathic surgery for correction of class III malocclusion. After measurement of 22 cephalometric parameters in posteroanterior cephalograms taken 1 month before orthognathic surgery, principal component analysis was performed to obtain 5 representative parameters [deviation (mm) of ANS (ANS-dev), maxillary central incisor contact point (Mx1-dev), and menton (Me-dev); cant (degree) of the maxillary anterior occlusal plane (MxAntOP-cant) and mandibular border (MnBorder-cant)]. K-means cluster analysis was conducted using these representative parameters. The differences in cephalometric parameters among the clusters were statistically analyzed. The FA phenotypes were classified into 4 types: No-cant-and-No-deviation type (cluster-4, n=16, 30.8%); MxMn-cant-MxMn-dev to the cleft-side type (cluster-3, n=4, 7.7%); Mx-cant-Mn-shift to the cleft-side type (cluster-2, n=15, 28.8%); and Mn-cant-Mn-dev to the noncleft-side type (cluster-1, n=17, 32.7%). Asymmetry in the maxilla and/or mandible were observed in 70% of patients. One third of patients (cluster-2 and cluster-3; sum, 36.5%) exhibited significant cant of MxAntOP induced by cleft and cant or shift of the mandible to the cleft side. Another one third of patients (cluster-1, 32.7%) demonstrated significant deviation and cant of the mandible to the noncleft-side despite cleft in the maxilla. This FA phenotype classification might be a basic guideline for diagnosis and treatment planning for UCLP patients. Hong, Mihee; Kim, Haeddeuri; Yang, Il-Hyung; Choi, Jin-Young; Lee, Jong-Ho; Kim, Myung-Jin; Chung, Jee Hyeok; Kim, Sukwha; Baek, Seung-Hak Kyungpook Natl Univ, Inst Translat Res Dent, Sch Dent, Dept Orthodont, Daegu, South Korea; Seoul Natl Univ Dent Hosp, Dept Orthodont, Seoul, South Korea; Seoul Natl Univ, Dent Res Inst, Sch Dent, Dept Orthodont, Seoul, South Korea; Seoul Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, Seoul, South Korea; Seoul Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, Seoul, South Korea; Angle Dent Clin, Seoul, South Korea; Seoul Natl Univ, Dept Plast & Reconstruct Surg, Childrens Hosp, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Plast Surg, Seongnam, South Korea; Seoul Natl Univ, Dent Res Inst, Sch Dent, Dept Orthodont, Daehak Ro 101, Seoul 03080, South Korea Choi, Jin-Young/AAF-5465-2019; Baek, Seung-Hak/NOE-8444-2025 57190379016; 58122183000; 23468146600; 58201805400; 56297700900; 56896224000; 55354194600; 57575007400; 35090967400 mhhong1208@gmail.com;totjt1@gmail.com;drortho@snu.ac.kr;jinychoi@snu.ac.kr;leejongh@snu.ac.kr;myungkim@snu.ac.kr;66012@snuh.org;kimsw55@cha.ac.kr;drwhite@unitel.co.kr; JOURNAL OF CRANIOFACIAL SURGERY J CRANIOFAC SURG 1049-2275 1536-3732 34 3 SCIE SURGERY 2023 1 71.4 1.41 2025-06-25 4 4 Class III malocclusion; cluster analysis; facial asymmetry; UCLP CHILDREN Class III malocclusion; cluster analysis; facial asymmetry; UCLP Cephalometry; Cleft Lip; Cleft Palate; Facial Asymmetry; Female; Humans; Malocclusion, Angle Class III; Maxilla; Principal Component Analysis; Retrospective Studies; angle class III malocclusion; cephalometry; cleft lip; cleft palate; diagnostic imaging; face asymmetry; female; human; maxilla; principal component analysis; retrospective study English 2023 2023-05 10.1097/scs.0000000000009284 바로가기 바로가기 바로가기 바로가기
Article Influence of Transforming Growth Factors beta 1 and beta 3 in the Scar Formation Process Background:Transforming growth factor-beta (TGF-& beta;) plays an instrumental role in forming scars and keloids. TGF-& beta; isoforms exhibit differential expression, indicating distinct wound healing and scar formation functions. However, the role of TGF-& beta;1 and TGF-& beta;3 in wound healing and scar formation remains unclear. This study aimed to compare the specific roles of TGF-& beta;1 and TGF-& beta;3 in wound healing and scar formation by biomolecular analysis. Materials and Methods:The study was conducted by cell isolation and culture cells from a total of 20 human samples. Normal human fibroblasts (NHF) were isolated from normal human samples and myofibroblasts from the different scar types, namely hypertrophic (HT) and keloid (K) scars. NHF and cells from the HT, and K scar, each of which were divided into 3 sample groups: the untreated control, TGF-& beta;1 (10 & mu;g/mL)-treated group, and TGF-& beta;3 (10 & mu;g/mL)-treated group. The results of confocal microscopy and fluorescence-activated cell sorting experiments were compared. Results:Both the HT and K groups had higher & alpha;-smooth muscle actin (& alpha;-SMA) expression than the NHF group in the untreated control group. In comparison with the untreated group, NHFs showed a significant increase in & alpha;-SMA expression in the TGF-& beta;1-treated group. HT showed a high & alpha;-SMA level, which was statistically significant compared with the normal fibroblasts. In the TGF-& beta;3-treated group, & alpha;-SMA expression was slightly increased in NHF as compared with the untreated group. TGF-& beta;3 treated HT exhibited a greater reduction in & alpha;-SMA expression than in the TGF-& beta;1 treated HT. K, on the other hand, had only a minimal effect on the treatment of TGF-& beta;1 and TGF-& beta;3. Conclusions:The findings suggest that TGF-& beta;3 may play a regulatory role in the wound repair process, which could be useful in the development of scar-reducing therapies for patients with scar-related cosmetic concerns. Lee, Joon Seok; Cho, Hyun Geun; Lee, Jeong Woo; Oh, Eun Jung; Kim, Hyun Mi; Ko, Ung Hyun; Kang, Minwoo; Shin, Jennifer H.; Chung, Ho Yun Kyungpook Natl Univ, Dept Plast & Reconstruct Surg, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, Daegu, South Korea; Korea Adv Inst Sci & Technol, Dept Mech Engn, Daejeon, South Korea; Kyungpook Natl Univ, Biomed Res Inst, Kyungpook Natl Univ Hosp, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, 130 Dongdeok Ro, Daegu 41944, South Korea ; LEE, JIN/Q-3108-2018; Kang, Min-woo/AAJ-5405-2020 56496041000; 57211205767; 55892173700; 35746789300; 57261065200; 55588876700; 58037994600; 7402724017; 7404007181 leejspo@knu.ac.kr;cg2448@naver.com;leejspo@naver.com;fullrest74@hanmail.net;sarang7939@naver.com;unghyunk@gmail.com;kangmw@kaist.ac.kr;j_shin@kaist.ac.kr;hy-chung@knu.ac.kr;chunghoyun@gmail.com; JOURNAL OF CRANIOFACIAL SURGERY J CRANIOFAC SURG 1049-2275 1536-3732 34 3 SCIE SURGERY 2023 1 71.4 2.12 2025-06-25 5 6 transforming growth factor beta 1; transforming growth factor beta3; fibroblast; myofibroblast; scar TGF-BETA; CONNECTIVE-TISSUE; GENE-EXPRESSION; TGF-BETA-3; KELOIDS; MYOFIBROBLAST; FIBROBLASTS; REPAIR fibroblast; myofibroblast; scar; transforming growth factor beta 1; transforming growth factor beta3 Cicatrix, Hypertrophic; Fibroblasts; Humans; Hypertrophy; Keloid; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta3; Transforming Growth Factors; transforming growth factor; transforming growth factor beta; transforming growth factor beta1; transforming growth factor beta3; fibroblast; human; hypertrophic scar; hypertrophy; keloid; metabolism English 2023 2023-05 10.1097/scs.0000000000009087 바로가기 바로가기 바로가기 바로가기
Review Is conservative management of partial zone II flexor tendon laceration possible? A systematic literature review and meta-analysis Background: There is still no consensus on managing zone II level partial flexor tendon lacerations, and the management of zone II partial flexor tendon injuries is controversial. No reliable large cohort studies or metaanalysis papers on partial flexor tendon laceration management are available in PubMed or Embase. Methods: We searched PubMed, Embase, Cochrane Library, Insight, Scopus, and Web of Science databases for primary research articles investigating outcomes of patients with partial flexor tendon injuries. The initial search was limited to human studies that were published from 1970-2021 and indexed as randomized controlled or clinical trials or observational, cross-sectional, or cohort studies. We used statistical package R version 4.1.2 for this meta-analysis. Results: The Standardised mean difference (SMD) of the common effects model was 2.020 (95% CI; 1.583-2.457; P < 0.0001), indicating that the results of conservative treatment without surgical intervention are similar to surgical intervention or better in some articles. The SMD of the random effect model was 7.093 (95% CI; 1.090-13.096; P < 0.0206), indicating the same result. Higgins' I2 value was 97.6%, indicating serious heterogeneity. Conclusions: In this first meta-analysis on flexor zone II conservative treatment, five papers with publication bias were analyzed. It is meaningful to verify the result of conservative treatment statistically. Even though this is a heterogeneous paper, conservative treatment seems to have a lot of benefits for the patient, including offering a fairly solid longterm prognosis with very few complications. Mo, Young Woong; Ryu, Da Hye; Cho, Gyo-Young; Hong, Jong Won Yonsei Univ, Severance Hosp, Dept Plast & Reconstruct Surg, Coll Med, 50-1 Yonsei Ro, Seoul 03722, South Korea; Yonsei Univ, Inst Human Tissue Restorat, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea 57215526629; 57934922200; 14043110800; 55503436100 hsaturn@hanmail.net; JOURNAL OF PLASTIC SURGERY AND HAND SURGERY J PLAST SURG HAND SU 2000-656X 2000-6764 57 1-6 SCIE ORTHOPEDICS;SURGERY 2023 1 71.4 0.39 2025-06-25 4 2 Partial; flexor tendon; tendon laceration; meta-analysis PERITENDINOUS ADHESIONS; REPAIR; 5-FLUOROURACIL flexor tendon; meta-analysis; Partial; tendon laceration Conservative Treatment; Cross-Sectional Studies; Humans; Lacerations; Tendon Injuries; Tendons; conservative treatment; cross-sectional study; human; laceration; meta analysis; tendon; tendon injury English 2023 2023-02-28 10.1080/2000656x.2022.2117704 바로가기 바로가기 바로가기 바로가기
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