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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Antimicrobial and plant growth-promoting activities of bacterial endophytes isolated from Calotropis procera (Ait.) WT Aiton | Bacterial endophytes are beneficial to their hosts as they can fix nitrogen in the soil and make it available to the host. Endophytic bacteria also secrete plant growth-promoting hormones to support their host plants under normal as well as stress conditions. The current study aimed to isolate endophytic bacteria from different parts of Calotropis procera, i.e., roots, stem and leaves of Calotropis procera (Ait.) W.T. Aiton. Plants were collected from the Lundkhwar, district Mardan. A total of 12 bacterial strains, i.e., six from roots, three from the stem and three from the leaves were isolated. The strains were screened for their growth-promoting activity in rice plants because rice shows a quick and easy response to the bioactive compounds present in the culture filtrate (CF) of the potent endophytic strains. The rice plants were cultivated in pots containing 30 mL of 0.8% w/v water-agar medium. The pots were placed in a growth chamber, operated at 28 +/- 0.3 degrees C for 14 h (day); and 25 +/- 0.3 degrees C for 10 h (night), at 70% relative-humidity. Among the isolated strains, R1, S1, S3, L1, R5 and R6 showed visible growth promotion in rice plants. The biochemical analysis revealed that the strains were able to produce indole acetic acid (IAA) and flavonoids in higher quantities. Moreover, the strains also produced bioactive compounds that inhibited the growth of Escherichia coli and Aspergillus flavus using the well diffusion method. From the results, it was concluded that these strains can secrete potent compounds that can promote the host plant growth and inhibit the growth of pathogenic microorganisms and, therefore, can be used as bio-fertilizer and bio-control agents. | Hamayun, Muhammad; Khan, Nasir; Khan, Muhammad Nauman; Qadir, Muhammad; Hussain, Anwar; Iqbal, Amjad; Khan, Sumera Afzal; Rehman, Khushnood Ur; Lee, In-Jung | Abdul Wali Khan Univ Mardan, Dept Bot, Plant Microbe Interact Lab, Kp, Pakistan; Bacha Khan Univ Charsadda, Dept Bot, Charsadda 24420, Pakistan; Abdul Wali Khan Univ Mardan, Dept Food Sci & Technol, Mardan 23200, Pakistan; Univ Peshawar, Ctr Biotechnol & Microbiol, Peshawar 25000, Pakistan; Islamia Coll Univ, Dept Bot, Peshawar 25000, Pakistan; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea | Hamayun, Muhammad/B-1694-2010; Ur Rehman, Khushnood/AAZ-1451-2021; Hussain, Anwar/N-1605-2019; Iqbal, Amjad/E-2010-2014; Qadir, Muhammad/AFJ-3919-2022; Lee, In-Jung/GLS-0432-2022; Khan, Muhammad Nauman/Y-1981-2019; Khan, Abdul/H-5910-2011 | 59297330100; 57320375300; 57203813613; 57210988627; 35621772200; 10142205100; 9636646900; 57220007137; 16425830900 | hamayun@awkum.edu.pk;ijlee@knu.ac.kr; | BIOCELL | BIOCELL | 0327-9545 | 1667-5746 | 45 | 2 | SCIE | BIOLOGY | 2021 | 1.11 | 83.5 | 1.38 | 2025-07-30 | 25 | 24 | Endophytic bacteria; Growth promotion; Antimicrobial activity; Plant-microbe interaction | MEDICINAL-PLANT; RHIZOSPHERE; FUNGI | Antimicrobial activity; Endophytic bacteria; Growth promotion; Plant-microbe interaction | agar; fertilizer; flavonoid; indoleacetic acid; water; antimicrobial activity; Article; Aspergillus flavus; bacterial growth; bacterial strain; bacterium isolation; biochemical analysis; biological control agent; Calotropis procera; diffusion; endophyte; Escherichia coli; night; nonhuman; Pakistan; plant growth; plant growth-promoting bacterium; plant leaf; plant root; plant stem; relative humidity; rice; species cultivation | English | 2021 | 2021 | 10.32604/biocell.2021.013907 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effects of lead (Pb)-induced oxidative stress on morphological and physio-biochemical properties of rice | In rice, high concentration of lead (Pb) can cause phyto-toxicity affecting several physiological functions. Cultivation of rice varieties that are resistant to Pb-induced oxidative stress is an important management strategy in Pb-contaminated soils. In the current study, we evaluated four different rice cultivars for their response to Pb-induced stress. Three japonica type cultivars X-Jigna, Ediget, and Furat, and one Indica type cultivar Amber 33 were grown in soil containing different Pb concentrations (0 mM, 0.6 mM, and 1.2 mM). The soil was treated with 0 mM or 0.6 mM or 1.2 mM Pb solution one month prior to rice seedling transplantation. Thereafter, four-week-old rice seedlings were transplanted into the treated soil and their responses were observed until maturity. The data revealed that a highest concentration of Pb (1.2 mM) induced significant reduction in agronomic traits such as plant height, number of tillers per plant, number of panicles per plant, and number of spikelets per panicle in all the rice cultivars. However, least reduction in the agronomic traits was observed in X-Jigna, whereas the highest reduction in the agronomic traits was observed in Ediget. Antioxidant activity of catalase (CAT), peroxidase (POD), polyphenol oxidase (PPO), and superoxide dismutase (SOD), was evaluated along with the accumulation of superoxide ions (O-2(center dot-)), protein, proline, chlorophyll, sucrose, glucose, and fructose contents in all the rice cultivars. A significant increase in antioxidant activity and in the accumulation of proline and sucrose contents with the least reduction in the chlorophyll and protein contents was observed in X-Jigna suggesting that X-Jigna is the most tolerant among all the rice cultivars tested against Pb-stress. On the other hand, non-significant and slightly significant increase in the antioxidant activity, less accumulation of proline and sucrose contents, and higher reduction in the chlorophyll and protein contents was observed in Ediget, which further suggest that Ediget is the most susceptible rice cultivar to Pb-stress. In addition, the other rice cultivars Furat and Amber 33, were found to be moderately tolerant to Pb-induced oxidative stress. In summary, our results suggest that tolerance to Pb-induced oxidative stress would be a result of a synergetic action of both enzymatic and non-enzymatic antioxidant systems, leading to a balanced redox status in rice. | Khan, Murtaza; Al Azzawi, Tiba Nazar Ibrahim; Imran, Muhammad; Hussain, Adil; Mun, Bong-Gyu; Pande, Anjali; Yun, Byung-Wook | Kyungpook Natl Univ, Sch Appl Biosci, Lab Plant Funct Genom, Daegu 41566, South Korea; Minist Agr State Co Agr Supplies, Baghdad 10064, Iraq; Kyungpook Natl Univ, Sch Appl Biosci, Lab Crop Physiol, Daegu 41566, South Korea; Abdul Wali Khan Univ Mardan, Dept Entomol, Khyber Pakhtunkhwa 23200, Pakistan | Hussain, Dr. Adil/K-6016-2018; Imran, Muhammad/AFL-6590-2022; Pande, Anjali/ABH-2333-2021; Mun, BongGyu/GYD-6010-2022 | 57207990116; 57226564955; 58282433800; 41961162600; 57147241300; 57222624154; 8245123600 | murtazakhan.bio@gmail.com;bwyun@knu.ac.kr; | BIOCELL | BIOCELL | 0327-9545 | 1667-5746 | 45 | 5 | SCIE | BIOLOGY | 2021 | 1.11 | 83.5 | 1.38 | 2025-07-30 | 22 | 26 | Lead (Pb) toxicity; Oxidative stress; Morphological and physio-biochemical properties of rice | ANTIOXIDATIVE DEFENSE; OSMOTIC ADJUSTMENT; ENZYME-ACTIVITIES; SEED-GERMINATION; BRASSICA-NAPUS; METAL CONTENTS; NITRIC-OXIDE; TOXICITY; CADMIUM; GROWTH | Lead (Pb) toxicity; Morphological; Oxidative stress; Physio-biochemical properties of rice | English | 2021 | 2021 | 10.32604/biocell.2021.015954 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Rapid delivery of Cas9 gene into the tomato cv. 'Heinz 1706' through an optimized Agrobacterium-mediated transformation procedure | Solanum lycopersicum 'Heinz 1706' is a pioneer model cultivar for tomato research, whose whole genome sequence valuable for genomics studies is available. Nevertheless, a genetic transformation procedure for this cultivar has not yet been reported. Meanwhile, various genome editing technologies such as transfection of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) ribonucleoprotein complexes into cells are in the limelight. Utilizing the Cas9-expressing genotype possessing a reference genome can simplify the verification of an off-target effect, resolve the economic cost of Cas9 endonuclease preparation, and avoid the complex assembly process together with single-guide RNA (sgRNA) in the transfection approach. Thus, this study was designed to generate Cas9-expressing 'Heinz 1706' lines by establishing an Agrobacterium tumefaciens-mediated transformation (ATMT) procedure. Here, we report a rapid and reproducible transformation procedure for 'Heinz 1706' by fine-tuning various factors: A. tumefaciens strain, pre-culture and co-culture durations, a proper combination of phytohormones at each step, supplementation of acetosyringone, and shooting/rooting method. Particularly, through eluding subculture and simultaneously inducing shoot elongation and rooting from leaf cluster, we achieved a short duration of three months for recovering the transgenic plants expressing Cas9. The presence of the Cas9 gene and its stable expression were confirmed by PCR and qRT-PCR analyses, and the Cas9 gene integrated into the T-0 plant genome was stably transmitted to T-1 progeny. Therefore, we anticipate that our procedure appears to ease the conventional ATMT in 'Heinz 1706', and the created Cas9-expressing 'Heinz 1706' lines are ultimately useful in gene editing via unilateral transfection of sgRNA into the protoplasts. | Kassahun, Beemnet Mengesha; Kang, Beum-Chang; Bae, Su-Ji; Nam, Ye Jin; Mundo, Gretel Fonseca; Kang, Ga-Hui; Kim, Kyoungook; Han, Jeung-Sul | Kyungpook Natl Univ, Dept Hort, Daegu 41566, South Korea; Inst for Basic Sci Korea, Ctr Genome Engn, Daejeon 34047, South Korea; Cranfield Univ, Sch Water Energy & Environm, Cranfield MK43 0AL, Beds, England; Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu 41566, South Korea | 57222083376; 57188734085; 57195463630; 57222087121; 57222085030; 57222099284; 59082159300; 8277688900 | peterpan@knu.ac.kr; | BIOCELL | BIOCELL | 0327-9545 | 1667-5746 | 45 | 1 | SCIE | BIOLOGY | 2021 | 1.11 | 83.5 | 0.07 | 2025-07-30 | 2 | 2 | Transgenic plant; Phytohormone; Acetosyringone; Gene editing | MICRO-TOM; PLANT-REGENERATION; TRANSGENIC PLANTS; EFFICIENT; RESISTANCE; SELECTION; GENOTYPE; RECOVERY; GROWTH; VIRUS | Acetosyringone; Gene editing; Phytohormone; Transgenic plant | acetosyringone; guide RNA; single guide RNA; unclassified drug; Agrobacterium tumefaciens; Article; bacterial strain; bacterium culture; Cas9 gene; controlled study; CRISPR-CAS9 system; gene cluster; gene editing; gene expression; genotype; nonhuman; plant gene; plant leaf; plant root; ploidy; polymerase chain reaction; progeny; promoter region; protoplast; real time polymerase chain reaction; real time reverse transcription polymerase chain reaction; shoot; tomato | English | 2021 | 2021 | 10.32604/biocell.2021.012353 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Calculation of molecular weight distribution using extended Cole-Cole model and quadratic mixing rule | We suggest a numerical method to calculate molecular weight distribution from linear viscoelastic data. The calculation method consists of three components: (1) a viscoelastic model of a monodisperse polymer as a function of molecular weight; (2) the mixing rule connecting viscoelastic data of monodisperse and polydisperse polymers through molecular weight distribution; (3) an algorithm which calculates the molecular weight distribution from the chosen mixing rule. Since we cannot measure the relaxation modulus of all monodisperse samples, we need an accurate monodisperse model for any molecular weight. It is known that a dynamic test is more reliable than a relaxation test, while the mixing rule needs relaxation modulus. Hence, we should have a smart numerical method that can convert dynamic data to relaxation modulus with the minimum conversion error. If we use the numerical method, then we have to generate numerical data from the model. Then it takes quite a long time. On the other hand, if we have a monodisperse model with the analytical relaxation spectrum, then calculation time can be reduced dramatically. Since the conversion from relaxation modulus to dynamic modulus suffers from smaller errors than the reverse conversion because of ill-posedness of the interconversion, the analytical conversion can be implemented more quickly at an acceptable level of errors. This paper proposes a new method satisfying the requirements. | Lee, Junghaeng; Kim, Sangmo; Cho, Kwang Soo | Kyungpook Natl Univ, Dept Polymer Sci & Engn, Daegu, South Korea; S OIL, Seoul, South Korea | 57198781113; 57200994831; 56316379300 | polphy@knu.ac.kr; | KOREA-AUSTRALIA RHEOLOGY JOURNAL | KOREA-AUST RHEOL J | 1226-119X | 2093-7660 | 33 | 1 | SCIE | MECHANICS;POLYMER SCIENCE | 2021 | 1.404 | 83.7 | 0.21 | 2025-07-30 | 3 | 3 | molecular weight distribution; extended Cole-Cole model; quadratic mixing rule; fixed point iteration; continuous relaxation time distribution | RELAXATION-TIME SPECTRUM; VISCOELASTIC PROPERTIES; LINEAR VISCOELASTICITY; STRESS-RELAXATION; DYNAMIC MODULI; TUBE-RENEWAL; POLYMERS; REPTATION; DEPENDENCE | continuous relaxation time distribution; extended Cole-Cole model; fixed point iteration; molecular weight distribution; quadratic mixing rule | English | 2021 | 2021-02 | 10.1007/s13367-021-0006-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Direct conversion of creep data to dynamic moduli using point-wise method | We developed a new numerical method which converts creep data to dynamic moduli without relying on viscoelastic spectra of relaxation or retardation times. This algorithm is an improvement of the previous ones (Kwon et al., 2016) in the reduction of artificial waviness in the terminal regime as well as the noise due to measurement errors. The method is the application of the point-wise polynomial regression which reduces the polynomial order dramatically compared with previous method in order to suppress the waviness. | Kim, Sihyun; Lee, Junghaeng; Cho, Kwang Soo | Kyungpook Natl Univ, Dept Polymer Sci & Engn, Korea, South Korea | 57198779479; 57198781113; 56316379300 | polphy@knu.ac.kr; | KOREA-AUSTRALIA RHEOLOGY JOURNAL | KOREA-AUST RHEOL J | 1226-119X | 2093-7660 | 33 | 2 | SCIE | MECHANICS;POLYMER SCIENCE | 2021 | 1.404 | 83.7 | 0.14 | 2025-07-30 | 2 | 2 | creep test; dynamic modulus; direct conversion; relaxation spectrum; linear viscoelasticity | RELAXATION SPECTRUM | creep test; direct conversion; dynamic modulus; linear viscoelasticity; relaxation spectrum | English | 2021 | 2021-05 | 10.1007/s13367-021-0009-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Droplet-based microextraction - when to go with the flow? | Over the last few decades, droplets have been used for enrichment of target compounds from various types of samples including water, body fluids, soils, and food. Leveraging the high surface area-to-volume ratio, droplets are excellent means of rapidly concentrating the target compounds. The droplet-based microextraction technologies reported so far can be categorized as static and continuous. For a static method, droplets are exposed to a given amount of sample while for a continuous method the sample is continuously fed by a flow and the droplets can either remain static or move with the sample flow. Both the extraction performance and types of analyses that can be used depend on whether the method is static or continuous microextraction. This review classifies various droplet-based microextraction techniques as either a static or continuous method and discusses the advantages and drawbacks of each. | You, Jae Bem | Kyungpook Natl Univ, Dept Chem Engn, Daegu, South Korea | You, Jae/C-6211-2019 | 55619455300 | jb.you@knu.ac.kr; | KOREA-AUSTRALIA RHEOLOGY JOURNAL | KOREA-AUST RHEOL J | 1226-119X | 2093-7660 | 33 | 3 | SCIE | MECHANICS;POLYMER SCIENCE | 2021 | 1.404 | 83.7 | 0.02 | 2025-07-30 | 2 | 2 | droplet; liquid-liquid microextraction; interface | LIQUID-LIQUID-EXTRACTION; DEEP EUTECTIC SOLVENTS; SURFACE NANODROPLETS; PHASE MICROEXTRACTION; MICROFLUIDIC PLATFORM; PESTICIDES; ARRAY; SYSTEM; PROBE; SPECTROMETRY | droplet; interface; liquid-liquid microextraction | English | 2021 | 2021-08 | 10.1007/s13367-021-0016-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | In vitro modulatory effects of ginsenoside compound K, 20(S)-protopanaxadiol and 20(S)-protopanaxatriol on uridine 5′-diphospho-glucuronosyltransferase activity and expression | We explored the inhibitory effect of ginsenoside compound K (CK), 20(S)-protopanaxadiol (PPD), and 20(S)-protopanaxatriol (PPT) on six uridine 5 '-diphospho-glucuronosyltransferase (UGT) enzyme (UGT1A1, 1A3, 1A4, 1A6, 1A9, and 2B7) activities in human liver microsomes (HLMs) and 10 UGT enzyme (UGT1A1, 1A3, 1A4, 1A6, 1A9, 2B4, 2B7, 2B10, 2B15, and 2B17) activities in recombinant UGT isoforms. PPD was a potent inhibitor of UGT1A3 activity with half-maximal inhibitory concentration values of 5.62 and 3.38 mu M in HLMs and recombinant UGT1A3, respectively. UGT1A3 inhibition by CK and PPD was competitive with inhibitory constant (K-i) values of 17.4 and 1.21 mu M, respectively, and inhibition by PPT was non-competitive with a K-i value of 8.07 mu M in HLMs. PPD exhibited more than 3.4-fold selectivity for UGT1A3 inhibition compared with other UGT isoforms inhibition, while CK and PPT showed more than 2.16- and 2.21-fold selectivity, respectively. PPD did not significantly increase the mRNA expression of UGT1A1, 1A3, 1A4, 1A9, and 2B7 in hepatocytes. Given the low plasma concentrations of PPD in healthy human subjects and the absence of induction potential on UGT isoforms, we conclude that PPD cause no pharmacokinetic interactions with other co-administered drugs metabolised by UGT1A3. | Jang, Su-Nyeong; Park, So-Young; Lee, Hyunyoung; Jeong, Hyojin; Jeon, Ji-Hyeon; Song, Im-Sook; Kwon, Mi Jeong; Liu, Kwang-Hyeon | Kyungpook Natl Univ, BK21 FOUR KNU Community Based Intelligent Novel D, Coll Pharm, Daegu, South Korea; Kyungpook Natl Univ, Coll Pharm, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu, South Korea; Kyungpook Natl Univ, Mass Spectrometry Based Convergence Res Inst, Daegu, South Korea | 57211630666; 57211630074; 57199179239; 57226758743; 57204685946; 7201564500; 35278164800; 55768214700 | mjkwon94@knu.ac.kr;dstlkh@knu.ac.kr; | XENOBIOTICA | XENOBIOTICA | 0049-8254 | 1366-5928 | 51 | 10 | SCIE | PHARMACOLOGY & PHARMACY;TOXICOLOGY | 2021 | 1.997 | 83.7 | 0.23 | 2025-07-30 | 3 | 3 | 5'-Diphospho-glucuronosyltransferase; food-drug interactions; ginsenoside compound K; protopanaxadiol; protopanaxatriol | UDP-GLUCURONOSYLTRANSFERASES; PANAX-GINSENG; INHIBITION; GLUCURONIDATION; METABOLISM; ENZYME; VIVO; BIOTRANSFORMATION; PHARMACOKINETICS; SELECTIVITY | 5’-Diphospho-glucuronosyltransferase; food-drug interactions; ginsenoside compound K; protopanaxadiol; protopanaxatriol | Ginsenosides; Glucuronosyltransferase; Humans; Microsomes, Liver; Sapogenins; Uridine; 20 protopanaxadiol; 20 protopanaxatriol; androsterone; berberine; chenodeoxycholic acid; compound k; cotinine; firtecan; fluconazole; ginsenoside; ginsenoside Rc; glucuronosyltransferase; glucuronosyltransferase 1A1; glucuronosyltransferase 1A3; glucuronosyltransferase 1A4; glucuronosyltransferase 1A6; glucuronosyltransferase 1A9; glucuronosyltransferase 2B7; glyceraldehyde 3 phosphate dehydrogenase; glycosyltransferase inhibitor; hecogenin; isoprotein; messenger RNA; mycophenolic acid; n acetylserotonin; naloxone; nilotinib; recombinant enzyme; schisandrin a; testosterone; trifluoperazine; unclassified drug; ginsenoside; ginsenoside M1; glucuronosyltransferase; protopanaxadiol; protopanaxatriol; sapogenin; uridine; Article; comparative study; controlled study; cryopreservation; drug blood level; drug determination; drug effect; drug glucuronidation; drug potency; electrospray; enzyme activity; enzyme inhibition; human; human cell; IC50; in vitro study; inhibition constant; inhibition kinetics; kinetic parameters; liquid chromatography-mass spectrometry; liver cell; liver microsome; Michaelis constant; pharmacokinetic parameters; protein expression; reverse transcription polymerase chain reaction; liver microsome | English | 2021 | 2021-10-03 | 10.1080/00498254.2021.1963503 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | 20(S)-Ginsenoside Rh2 Suppresses Oral Cancer Cell Growth by Inhibiting the Src-Raf-ERK Signaling Pathway | Background: 20(S)-Ginsenoside Rh2 (G-Rh2) has demonstrated therapeutic effects in many types of cancers. We aimed to investigate the potential anticancer activity and underlying mechanisms of G-Rh2 in oral cancer cells. Materials and Methods: The antigrowth effect of G-Rh2 in oral cancer cells was stimulated by cell proliferation, soft agar colony formation, and migration and invasion assay. The cell cycle and apoptosis were detected by flow cytometry. The underlying mechanism of G-Rh2 in oral cancer cells was explored by immunoblotting . Results: G-Rh2 significantly inhibited oral cancer cell growth by inducing apoptosis and cell cycle G(0)/G(1)-phase arrest. G-Rh2 inhibited oral cancer cell migration and invasion through regulation of epithelial-mesenchymal transition (EMT)-related proteins. G-Rh2 inhibited the Src/Raf/ERK signaling pathway in YD10B and Ca9-22 cells. Conclusion: G-Rh2 exerted anticancer activity in vitro by inhibiting the Src/Raf/ERK signaling pathway in oral cancer. G-Rh2 is a potential therapeutic drug for oral cancer treatment. | Zhang, Haibo; Yi, Junkoo; Kim, Eungyung; Choo, Yeonsik; Hai, Huang; Kim, Kirim; Kim, Eun-Kyong; Ryoo, Zaeyoung; Kim, Myoungok | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju, South Korea; Gyeongsangbukdo Livestock Inst Res, Yeongju, South Korea; Kyungpook Natl Univ, Dept Biol, Coll Natl Sci, Daegu, South Korea; Kyungpook Natl Univ, Dept Dent Hyg, Sangju, South Korea; Kyungpook Natl Univ, Sch Life Sci, Daegu 41566, South Korea | Yi, Junkoo/JBR-8507-2023; Zhang, Haibo/HLP-9266-2023 | 57221648126; 56182537200; 57217871658; 26040458100; 57221647237; 35793746200; 55915892100; 16937104900; 8934745900 | jaewoong64@hanmail.net;ok4325@knu.ac.kr; | ANTICANCER RESEARCH | ANTICANCER RES | 0250-7005 | 1791-7530 | 41 | 1 | SCIE | ONCOLOGY | 2021 | 2.435 | 83.9 | 0.83 | 2025-07-30 | 15 | 17 | 20(S)-Ginsenoside Rh2; Src; ERK; oral cancer | EXERTS ANTICANCER ACTIVITY; GINSENOSIDE RH2; CARCINOMA-CELLS; BREAST-CANCER; PROLIFERATION; APOPTOSIS; RESISTANCE; KINASES; ROS | 20(S)-Ginsenoside Rh2; ERK; Oral cancer; Src | Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Ginsenosides; Humans; Mouth Neoplasms; raf Kinases; Signal Transduction; src-Family Kinases; cyclin D1; cyclin dependent kinase 4; cyclin dependent kinase 6; cyclin E; ginsenoside Rh 2; mitogen activated protein kinase; nerve cell adhesion molecule; protein tyrosine kinase; Raf protein; uvomorulin; vimentin; antineoplastic agent; ginsenoside; ginsenoside Rh 2; mitogen activated protein kinase; protein tyrosine kinase; Raf protein; antineoplastic activity; antiproliferative activity; apoptosis; Article; cancer growth; cancer inhibition; cell density; cell invasion; cell migration; cell proliferation; cell viability assay; colony formation; controlled study; epithelial mesenchymal transition; flow cytometry; G1 phase cell cycle checkpoint; human; human cell; metastasis; metastasis inhibition; migration inhibition; mouth cancer; oral cancer cell line; priority journal; signal transduction; Western blotting; cell cycle; cell motion; chemistry; drug effect; metabolism; mouth tumor; tumor cell line | English | 2021 | 2021-01 | 10.21873/anticanres.14769 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Applicability of the Histoculture Drug Response Assay to Predict Platinum Sensitivity and Prognosis in Ovarian Cancer | Background/Aim: To retrospectively analyze the results of histoculture drug response assays (HDRAs) to determine whether the results could predict platinum sensitivity and prognosis in ovarian cancer. Patients and Methods: One hundred thirty-nine patients with ovarian cancer were reviewed. HDRAs were conducted for platinum and taxane agents. Platinum resistance and sensitivity occurred in 21 and 118 patients, respectively. To analyze the relationship between the inhibition rates (IRs) of tumor growth caused by the platinum agent and clinical outcomes, Student's t-test and linear regression analysis were used. Results: We found that the average IRs of the platinum and taxane agent were not statistically significant between the platinum-sensitive and resistant groups. There was no statistical significance for overall survival, progression-free survival, or platinum-free interval. Conclusion: The HDRA is not useful for predicting platinum sensitivity and survival outcomes. | Lee, Juhun; Kim, Jong Mi; Lee, Yoon Hee; Chong, Gun Oh; Hong, Dae Gy | Kyungpook Natl Univ, Dept Obstet & Gynecol, Chilgok Hosp, 807 Hoguk Ro, Daegu 41404, South Korea | 57360628800; 57212764251; 37088851700; 23099068000; 26656670100 | dghong@knu.ac.kr; | ANTICANCER RESEARCH | ANTICANCER RES | 0250-7005 | 1791-7530 | 41 | 12 | SCIE | ONCOLOGY | 2021 | 2.435 | 83.9 | 0.14 | 2025-07-30 | 2 | 2 | Chemotherapy; histoculture drug response assay; in vitro tumor response assay; ovarian cancer; platinum resistance; platinum sensitivity | CHEMOTHERAPY; CRITERIA; TRIAL | Chemotherapy; Histoculture drug response assay; In vitro tumor response assay; Ovarian cancer; Platinum resistance; Platinum sensitivity | Antineoplastic Agents; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Ovarian Neoplasms; Platinum; Prognosis; Retrospective Studies; Survival Analysis; antineoplastic metal complex; belotecan; bevacizumab; carboplatin; cisplatin; docetaxel; doxorubicin; gemcitabine; irinotecan; paclitaxel; taxane derivative; topotecan; antineoplastic agent; platinum; adult; Article; assay; cancer combination chemotherapy; cancer patient; cancer prognosis; clinical outcome; drug sensitivity; female; histoculture drug response assay; human; Korean (people); major clinical study; medical record review; middle aged; multiple cycle treatment; oncological parameters; ovary cancer; overall survival; platinum free interval; progression free survival; retrospective study; tumor growth; drug effect; drug resistance; mortality; ovary tumor; prognosis; survival analysis | English | 2021 | 2021-12 | 10.21873/anticanres.15450 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical Impact of Postoperative Vitamin D Deficiency on the Recurrence of Colon Cancer After Curative Surgical Resection | Background/Aim: There are no clinically significant cutoff values of serum vitamin D levels and time points to predict the prognosis of colon cancer, particularly in patients who underwent curative surgical resection. Patients and Methods: We retrospectively analyzed serum vitamin D levels in 795 patients with stages I to III colon cancer who underwent curative surgical resection. Results: Patients with vitamin D levels below 12 ng/ml at one year after surgical resection demonstrated a significantly reduced disease-free survival (DFS) than those who did not have vitamin D deficiency (p=0.01). In the multivariate analysis, an age of 70 years or older [hazard ratio (HR)=1.992; p=0.001], pathologic stage (HR=3.739; p<0.001), and vitamin D deficiency (less than 12 ng/ml) at one year after surgery (HR=0.563; p=0.020) were factors unfavorably influencing DFS. Conclusion: In patients with stages I to III of colon cancer, vitamin D deficiency at one year after surgical resection was associated with increased disease relapse. | Kim, Juhyung; Baek, Dong Won; Baek, Jin Ho; Kang, Byung Woog; Song, Seung Ho; Kim, Hye Jin; Park, Soo Yeun; Park, Jun Seok; Choi, Gyu-Seog; Kim, Jong Gwang | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Canc Res Inst,Dept Oncol Hematol, 807 Hogukno, Daegu 41404, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Surg, Daegu, South Korea | Kim, Hye/W-1059-2019; Park, Joonhong/AAZ-9885-2020 | 58739544500; 57191874272; 57217075847; 28567838500; 57221771693; 57204567554; 40561578300; 35226761100; 8058759100; 59501049300 | kyuschoi@mail.knu.ac.kr;jkk21c@knu.ac.kr; | ANTICANCER RESEARCH | ANTICANCER RES | 0250-7005 | 1791-7530 | 41 | 7 | SCIE | ONCOLOGY | 2021 | 2.435 | 83.9 | 0.34 | 2025-07-30 | 5 | 6 | Key Words; Colon cancer; tumor resection; disease relapse; serum vitamin D; prognostic indicator | COLORECTAL-CANCER; 25-HYDROXYVITAMIN D; SURVIVAL; SUPPLEMENTATION; POLYMORPHISMS; PREVENTION; CELLS | Colon cancer; Disease relapse; Prognostic indicator; Serum vitamin D; Tumor resection | Adolescent; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Disease-Free Survival; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Postoperative Period; Prognosis; Retrospective Studies; Vitamin D; Vitamin D Deficiency; Young Adult; vitamin D; vitamin D; adolescent; adult; aged; Article; cancer patient; cancer recurrence; cancer staging; cancer surgery; clinical outcome; colon cancer; controlled study; disease free survival; female; hazard ratio; human; human tissue; major clinical study; male; retrospective study; vitamin blood level; vitamin D deficiency; colon tumor; metabolism; middle aged; pathology; postoperative period; procedures; prognosis; tumor recurrence; very elderly; vitamin D deficiency; young adult | English | 2021 | 2021-07 | 10.21873/anticanres.15159 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinically Applicable Serum Biomarkers Among 14 Candidates Associated With Recurrence of Stage II and III Colorectal Cancer | Background/Aim: We evaluated the predictive value of candidate serum biomarkers for recurrence in stage II and III colorectal cancer (CRC) after curative surgery. Patients and Methods: A total of 33 and 120 patients with CRC with or without recurrence at 5 years after curative surgery were included in the training set and the validation set, respectively. Possible serum biomarkers were examined for associations with CRC recurrence using receiver operating characteristics (ROC) curve analysis. Results: In the training set, the expression levels of the 14 biomarkers were compared according to recurrence. Among them, five biomarkers that had significantly different expression levels were validated in 60 patients with recurrence at 5 years after curative surgery and 60 patients without. Multivariate analysis showed that natural log-transformed values of carcinoembryonic antigen (CEA), cyclin-dependent kinase regulatory subunit 2 (CKS2), 2'-5'-oligoadenylate synthetase 2 (OAS2), and autophagy-related gene 5 (ATG5) in preoperative serum were significantly related to recurrence. ROC analysis showed that these biomarkers were able to discriminate patients with recurrence from those without (area under the curve=0.828, 95% confidence interval=0.755-0.990). Conclusion: Preoperative serum levels of CEA, CKS2, OAS2 and ATG5 were independent risk factors for recurrence. A combination of serum CEA, CKS2, OAS2 and ATG5 predicted tumor recurrence well in patients with stage II and III CRC. | Kim, Chan Wook; HA, Ye Jin; Tak, Ka Hee; Roh, Seon Ae; Kim, Seon-Kyu; Kim, Seon-Young; Kim, Yong Sung; Cho, Dong-Hyung; Kim, Jin Cheon | Univ Ulsan, Dept Surg, Asan Med Ctr, Coll Med, 88 Olymp Ro 43-gil, Seoul 05505, South Korea; Univ Ulsan, Asan Inst Life Sci, Asan Med Ctr, Coll Med, Seoul, South Korea; Korea Res Inst Biosci & Biotechnol, Personalized Genom Med Res Ctr, Daejeon, South Korea; Kyungpook Natl Univ, Sch Life Sci, Daegu, South Korea | Bin Kim, Hong/J-5452-2012; Kim, Seon-Kyu/KBA-0395-2024; Kim, Seon-Young/A-7193-2009; Choi, Hye Rin/JDV-9065-2023 | 55966571500; 38561431400; 55363346300; 35201933500; 13410554000; 55146733100; 56570975100; 35093684400; 55664401800 | jckim@amc.seoul.kr; | ANTICANCER RESEARCH | ANTICANCER RES | 0250-7005 | 1791-7530 | 41 | 9 | SCIE | ONCOLOGY | 2021 | 2.435 | 83.9 | 0 | 2025-07-30 | 0 | 0 | Colorectal cancer; biomarkers; recurrence; CEA; CKS2; OAS2; ATG5 | CARCINOEMBRYONIC ANTIGEN; UP-REGULATION; EXPRESSION; PROGNOSIS; GENES; IDENTIFICATION; CLASSIFIER; AUTOPHAGY; PREDICTS; MARKERS | Atg5; Biomarkers; Cea; Cks2; Colorectal cancer; Oas2; Recurrence | 2',5'-Oligoadenylate Synthetase; Aged; Autophagy-Related Protein 5; Biomarkers, Tumor; Carcinoembryonic Antigen; CDC2-CDC28 Kinases; Cell Cycle Proteins; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasm Staging; ROC Curve; 2',5' oligoadenylate synthetase; autophagy related protein 5; biological marker; carcinoembryonic antigen; cyclin dependent kinase; cyclin dependent kinase 2; 2',5' oligoadenylate synthetase; ATG5 protein, human; autophagy related protein 5; carcinoembryonic antigen; cell cycle protein; CKS2 protein, human; cyclin dependent kinase; OAS2 protein, human; tumor marker; adult; Article; cancer recurrence; cancer surgery; colorectal cancer; controlled study; female; human; human tissue; major clinical study; male; metastasis; predictive value; preoperative period; protein blood level; protein expression level; receiver operating characteristic; aged; blood; cancer staging; colorectal tumor; comparative study; diagnosis; middle aged; multivariate analysis; pathology; tumor recurrence | English | 2021 | 2021-09 | 10.21873/anticanres.15279 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Comparison of the Effect of Steroids on the Treatment of Phimosis according to the Steroid Potencies | Purpose: This study aimed to evaluate the outcomes of topical steroid therapy according to potency as the first-line treatment for boys with symptomatic phimosis. Materials and Methods: From April 2017 to March 2019, we retrospectively reviewed 45 boys with severe phimosis (Kikiros retractability grade 4 or 5) who presented with phimosis-related complications. During the first year of the study period, methylprednisolone aceponate (MPA, Advantan (R), potent topical steroid) was administered in 24 boys. Hydrocortisone butyrate (HCB, Bandel (R), moderately potent topical steroid) was administered in 21 boys in the subsequent period. Topical steroids were administered for 4-8 weeks in all patients. Success of the therapy was determined by two conditions at 3 months after therapy: achieving Kikiros grade 3 and less with disappearance of symptoms. Results: Of 45 boys, 35 (77.8%) achieved success of the therapy. Mean age was 46.64 +/- 22.42 months. Recurrence of phimosis with clinical complications was confirmed in three of 35 patients with initial success (8.6%) during the follow-up period. All boys with recurrence showed remission after additional topical steroid therapy. Success rate of the MPA group was higher than that of the HCB group (91.7% and 61.9% respectively, P = .029). Side effects associated with the topical steroid application were not observed in all children. Conclusion: Topical steroid application is an effective and safe procedure as first-line treatment in symptomatic boys with severe phimosis. Moreover, the potency of topical steroids for the treatment of phimosis is considered a factor affecting the success rate. | Chung, Jae-Wook; Kim, Hyun Tae; Jang, Se Won; Ha, Yun-Sok; Kim, Tae-Hwan; Kwon, Tae Gyun; Lee, Jun Nyung | Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ, Joint Inst Regenerat Med, Daegu, South Korea | Kim, Tae/B-9921-2013 | 35204798500; 55739531300; 57428381500; 35487226400; 57797823600; 15073765400; 16301364600 | ljnlover@gmail.com; | UROLOGY JOURNAL | UROL J | 1735-1308 | 1735-546X | 18 | 6 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 1.555 | 83.9 | 0.15 | 2025-07-30 | 1 | 1 | phimosis; steroid; potency | TOPICAL HYDROCORTISONE; BETAMETHASONE; FORESKIN | phimosis; potency; steroid | Administration, Topical; Child; Child, Preschool; Humans; Male; Phimosis; Retrospective Studies; Steroids; Treatment Outcome; steroid; child; human; male; phimosis; preschool child; retrospective study; topical drug administration; treatment outcome | English | 2021 | 2021 (NOV-DEC) | 10.22037/uj.v18i.6574 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Decrease of Preoperative Serum Albumin-to-Globulin Ratio as a Prognostic Indicator after Radical Cystectomy in Patients with Urothelial Bladder Cancer | Purpose: This study aims to evaluate whether preoperative serum albumin-to-globulin ratio (AGR) could predict the prognosis of patients with urothelial bladder cancer (UBC) after radical cystectomy (RC). Materials and Methods: A total of 176 patients with UBC who underwent RC in a tertiary hospital between 2008 and 2019 were retrospectively analyzed. The AGR was calculated as albumin/(total protein - albumin). In addition, the AGR was divided into two groups for the time-dependent receiver operating characteristic curve (ROC) analysis. Survival was estimated using the Kaplan-Meier analysis and compared using the log-rank test. Cox proportional-hazards models were used for multivariate survival analysis. Results: The best cutoff AGR value for metastasis prediction was 1.32 based on the ROC curve analysis. Patients who had lower pretreatment AGR (<1.32) values composed the low-AGR group (n = 57; 32.4%). On the other hand, the remaining patients (n = 119; 67.6%) composed the high-AGR group. The patients in the low-AGR group had more advanced stage tumors compared with the patients in the high-AGR group. The Kaplan-Meier curves revealed that the patients in the low-AGR group had significantly lower rates of metastasis-free survival (MFS) and cancer-specific survival (CSS). The multivariate Cox regression analysis showed that preoperative AGR was an independent prognostic factor for MFS and CSS. Conclusion: In this single-institution retrospective study, lower preoperative AGR values demonstrated a poor prognostic effect on MFS and CSS in patients with UBC who underwent RC. | Oh, Jeong Seock; Park, Dong Jin; Byeon, Kyeong-Hyeon; Ha, Yun-Sok; Kim, Tae-Hwan; Yoo, Eun Sang; Kwon, Tae Gyun; Kim, Hyun Tae | Kyungpook Natl Univ Hosp, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ, Dept Urol, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Dongguk Univ, Sch Med, Dept Urol, Gyeongju, South Korea | Kim, Tae/B-9921-2013 | 57688295200; 57220636322; 57204423048; 35487226400; 57797823600; 7006609239; 15073765400; 55739531300 | urologistk@knu.ac.kr; | UROLOGY JOURNAL | UROL J | 1735-1308 | 1735-546X | 18 | 1 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 1.555 | 83.9 | 1.18 | 2025-07-30 | 8 | 9 | cystectomy; prognosis; serum albumin; serum globulins; survival; urinary bladder neoplasms | SYSTEMIC INFLAMMATION; CARCINOMA; GUIDELINES; PATHOLOGY; MORTALITY; SURVIVAL | cystectomy; prognosis; serum albumin; serum globulins; survival; urinary bladder neoplasms | Aged; Carcinoma, Transitional Cell; Cystectomy; Female; Globulins; Humans; Male; Middle Aged; Preoperative Period; Prognosis; Retrospective Studies; Serum Albumin; Survival Rate; Urinary Bladder Neoplasms; globulin; serum albumin; aged; bladder tumor; blood; cystectomy; female; human; male; middle aged; mortality; preoperative period; procedures; prognosis; retrospective study; survival rate; transitional cell carcinoma | English | 2021 | 2021 (JAN-FEB) | 10.22037/uj.v16i7.6350 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Inter-institutional Variation in Intensity-modulated Radiotherapy for Breast Cancer in Korea (KROG 19-01) | Background/Aim: To present the variations in the target delineation and the planning results of intensity modulated radiation therapy (IMRT) for breast cancers. Patients and Methods: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation. Results: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heartdoses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case. Conclusion: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed. | Kim, Kyubo; Chun, Minsoo; Jin, Hyeongmin; Jung, Wonguen; Shin, Kyung Hwan; Shin, Seong Soo; Kim, Yeon Joo; Park, Shin-Hyung; Kim, Jin Hee; Kim, Yong Ho; Shin, Hyun Soo; Kim, Haeyoung; Kim, Su Ssan; Lee, Jong Hoon; Kim, Yong Bae; Lee, Sun Young; Choi, Jinhyun; Oh, Do Hoon; Kang, Ki Mun; Kwon, Jeanny; Kim, Mi Young; Koo, Taeryool; Park, Hae Jin; Ahn, Sung Ja | Ewha Womans Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Radiat Oncol, 101 Daehak Ro, Seoul 03080, South Korea; Univ Ulsan, GangNeung Asan Hosp, Coll Med, Dept Radiat Oncol, Kangnung, South Korea; Kangwon Natl Univ, Sch Med, Dept Radiat Oncol, Chunchon, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Keimyung Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Catholic Kwandong Univ, Dept Radiat Oncol, Incheon, South Korea; CHA Univ, Sch Med, Dept Radiat Oncol, Seongnam, South Korea; Sungkyunkwan Univ, Sch Med, Dept Radiat Oncol, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Radiat Oncol, Suwon, South Korea; Yonsei Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Jeonbuk Natl Univ, Sch Med, Dept Radiat Oncol, Jeonju, South Korea; Jeju Natl Univ, Sch Med, Dept Radiat Oncol, Jeju, South Korea; Chung Ang Univ, Coll Med, Dept Radiol, Seoul, South Korea; Gyeongsang Natl Univ, Sch Med, Dept Radiat Oncol, Chang Won, South Korea; Chungnam Natl Univ, Coll Med, Dept Radiat Oncol, Daejeon, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Hallym Univ, Coll Med, Dept Radiat Oncol, Anyang, South Korea; Hanyang Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Chonnam Natl Univ, Med Sch, Dept Radiat Oncol, Gwangju, South Korea | Park, Shinhyung/LNQ-6428-2024; Kim, Hye/AAF-7609-2020; Chun, Minsoo/C-4493-2014; Kim, Kyung-Min Kim/C-7007-2014; Kang, Kimun/AAA-3684-2022; KIM, JIN SU/U-2112-2019; Kim, Haeyoung/ABC-4815-2020; Shin, Kwang-Hee/C-5687-2012; Kim, Yong Sung/GMW-8652-2022; KIM, Yong/R-3111-2019 | 8213302900; 57192249342; 55443002100; 56714721300; 34873643900; 9434139100; 57311417000; 57203275843; 56441016600; 57059548400; 57225867754; 56007004100; 25627857300; 56558022100; 56080532600; 57203597345; 56714062800; 18537121600; 13003101000; 55888496100; 57204652164; 55598457600; 57201025307; 57211944596 | radiat@snu.ac.kr; | ANTICANCER RESEARCH | ANTICANCER RES | 0250-7005 | 1791-7530 | 41 | 6 | SCIE | ONCOLOGY | 2021 | 2.435 | 83.9 | 0.34 | 2025-07-30 | 5 | 5 | Key Words; Breast cancer; dose-volume constraint; intensity-modulated radiation therapy; target volume; variation | TARGET VOLUME DELINEATION; INTEROBSERVER VARIATION; ADJUVANT RADIOTHERAPY; VARIABILITY; RISK; IRRADIATION; ONCOLOGY; THERAPY; ORGANS; ATLAS | Breast cancer; Dose-volume constraint; Intensity-modulated radiation therapy; Target volume; Variation | Breast Neoplasms; Female; Humans; Interinstitutional Relations; Middle Aged; Organs at Risk; Radiotherapy, Intensity-Modulated; Republic of Korea; Article; breast cancer; cancer radiotherapy; clinical article; dose volume histogram; female; heart; human; intensity modulated radiation therapy; Korea; lung volume; mastectomy; organs at risk; partial mastectomy; planning target volume; radiation dose; radiation dose distribution; treatment planning; breast tumor; diagnostic imaging; intensity modulated radiation therapy; middle aged; procedures; public relations; South Korea | English | 2021 | 2021-06 | 10.21873/anticanres.15100 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | G-MGF based performance analysis of coherent FSO systems with multiple receivers | This letter investigates the performance of coherent free-space optical systems with multiple receivers especially through the generalised moment-generating function based approach. Specifically, we first derive a closed-form expression of the generalised moment-generating function of the signal-to-noise ratio for the coherent free-space optical systems. The derived generalised moment-generating function formula is further utilised to effectively analyse the several performance metrics such as amount of fading and ergodic capacity. The accuracy of our theoretical analyses are corroborated via some numerical results. | Jeong, Seongah; Kang, Jinkyu; Lee, Hoojin | Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea; Myongji Univ, Dept Informat & Commun Engn, Seoul, Gyeonggi Do, South Korea; Hansung Univ, Div IT Convergence Engn, Seoul, South Korea | Jeong, Seongah/I-2863-2017; Jeong, Seongah/ABW-7285-2022; Kang, Joonhyuk/C-1771-2011 | 55210226900; 56283062100; 57215913990 | hjlee@hansung.ac.kr; | ELECTRONICS LETTERS | ELECTRON LETT | 0013-5194 | 1350-911X | 57 | 7 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC | 2021 | 1.202 | 84.2 | 0.07 | 2025-07-30 | 2 | 2 | SPACE OPTICAL-SYSTEMS; GENERALIZED MGF | Free-space optical links; Optical communication equipment | Electronics engineering; Amount of fading; Closed-form expression; Ergodic capacity; Free space optical systems; Moment generating function; Multiple receivers; Performance analysis; Performance metrics; Signal to noise ratio | English | 2021 | 2021-03 | 10.1049/ell2.12038 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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