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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Permeable Reactive Barriers with Zero-Valent Iron and Pumice for Remediation of Groundwater Contaminated with Multiple Heavy Metals In this study, we present an optimized method for remediating multiple metals and metalloids using pumice permeable reactive barrier with zero-valent iron (ZVI) and with a modified reactor packing bed. The objective was to determine the effect of the contaminant breakthrough capacity of the modified bed, volumetric discharge of treated water, and the reactive material. Arsenic, manganese, iron, and zinc species with the initial concentrations of 0.001, 275.31, 0.61, and 0.063 mmol/L were used as the reference contaminants, respectively. ZVI and pumice were studied to remove the contaminants from synthetic groundwater. Contaminant breakthrough capacity (removal efficiency of 1) was not observed in the ZVI reactor bed with pumice for the 90-day period. The application of irregular reactive bed packing enhanced gas and water transport and removal of heavy metal(loid) for ZVI and pumice column reactor. Although contaminant breakthrough capacity (removal efficiency of 1) was not observed in the ZVI column reactor, clogging phenomena was characteristic. The column with only pumice exhibited zinc and manganese breakthrough capacity after 8 days owing to poor adsorption characteristics because the dominant remediation mechanism was cation exchange. Reactive material characteristics, and the remediation mechanism and for each reactive system, are described in this study. This study showed that the asymmetrical bed geometry could aid in the remediation process and venting of gas buildup. Njaramba, Lewis Kamande; Park, Jung-Bo; Lee, Chang-Soo; Nzioka, Antony Mutua; Kim, Young-Ju Kyungpook Natl Univ, Dept Environm & Energy Engn, Daegu, South Korea; En Tec One Co Ltd, Daegu, South Korea; Uiduk Univ, Dept Architecture & Fire Protect, Gyeongju Si, South Korea; Silla Entech Co Ltd, R&D Inst, Daegu, South Korea Park, Jung Hoon/CZZ-0090-2022; Kamande, Lewis/JLL-5435-2023; Nzioka, Antony Mutua/Y-4112-2018 57223183206; 57223193499; 57195304504; 57191056730; 55699531200 yjukim@knu.ac.kr; ENVIRONMENTAL ENGINEERING SCIENCE ENVIRON ENG SCI 1092-8758 1557-9018 38 4 SCIE ENGINEERING, ENVIRONMENTAL;ENVIRONMENTAL SCIENCES 2021 2.172 78.0 0.45 2025-07-30 10 12 groundwater; heavy metals; permeable reactive barrier; pumice; remediation; zero-valent iron ARSENIC REMOVAL; IRON/LAPILLUS MIXTURES; WATER; ADSORPTION; MANGANESE; DRAINAGE; GAS; PERFORMANCE; SPECIATION; CORROSION groundwater; heavy metals; permeable reactive barrier; pumice; remediation; zero-valent iron Contamination; Efficiency; Groundwater; Groundwater pollution; Heavy metals; Iron; Manganese; Remediation; Zinc; aluminum; arsenic; ground water; heavy metal; iron; iron nanoparticle; manganese; potassium; pumice; silicon; sodium; zinc chloride; Adsorption characteristic; Breakthrough capacity; Initial concentration; Permeable reactive barriers; Reactive materials; Removal efficiencies; Synthetic groundwater; Zero-valent iron; acid mine drainage; adsorption; Article; cation exchange; ecosystem restoration; gas transport; heavy metal removal; hydraulic conductivity; precipitation; water contamination; water sampling; water transport; X ray diffraction; Chemicals removal (water treatment) English 2021 2021-04-01 10.1089/ees.2020.0109 바로가기 바로가기 바로가기 바로가기
Meeting Abstract The Sirtuin 2 inhibitor suppresses allergic airway inflammation in mast cell-mediated asthma Kim, Y.; Kim, S.; Lee, S. Korea Res Inst Biosci & Biotechnol, Immunoregulatory Mat Res Ctr, Jeongeup, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Daegu, South Korea FEBS OPEN BIO FEBS OPEN BIO 2211-5463 11 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY 2021 2.792 78.0 0 English 2021 2021-07 바로가기 바로가기
Article Repair technique for a rare partial anomalous pulmonary venous return associated with retroaortic innominate vein Background Retroaortic innominate vein (RIV) is a rare vascular abnormality. Although RIV itself is asymptomatic, its presence in patients with partial anomalous pulmonary venous return (PAPVR) to the superior vena cava (SVC) is surgically challenging because a simple Warden procedure is impossible. Case presentation A 16-year-old girl was diagnosed with tetralogy of Fallot, secundum, and sinus venosus atrial septal defect (ASD) at birth. She underwent total correction of tetralogy of Fallot and ASD closure at the age of 14-months. However, the diagnosis of PAPVR was missed. At the age of 16, she developed dyspnea on exercise. Echocardiography demonstrated severe pulmonary regurgitation, mild tricuspid regurgitation, and D-shaped left ventricle with paradoxical septal motion along with RIV and sinus venous ASD. Computed tomography confirmed RIV and PAPVR. Systemic and pulmonary venous blood pathways were separated by bovine pericardial patch, and pulmonary valve replacement was performed. Postoperative echocardiography demonstrated improvement of D-shaped left ventricle and laminar flow through the SVC and pulmonary veins. Postoperative computed tomography showed a well-reconstructed SVC and pulmonary venous pathway without stenosis. After an uneventful postoperative course, patient was discharged. Conclusions PAPVR in patients with RIV may be surgically challenging to repair. We report the first case of successfully repaired PAPVR associated with RIV. Jung, Hanna; Cho, Joon Yong; Lee, Youngok Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Thorac & Cardiovasc Surg, 130 Dongdeok Ro, Daegu 41944, South Korea Jung, Hanna/Y-4165-2019 56467570700; 57195637434; 36461117600 yolee1210@knu.ac.kr; JOURNAL OF CARDIOTHORACIC SURGERY J CARDIOTHORAC SURG 1749-8090 16 1 SCIE CARDIAC & CARDIOVASCULAR SYSTEMS;SURGERY 2021 1.522 78.2 0 2025-07-30 0 0 Congenital heart disease; Partial anomalous pulmonary venous return; Retroaortic innominate vein Congenital heart disease; Partial anomalous pulmonary venous return; Retroaortic innominate vein Adolescent; Animals; Aorta; Brachiocephalic Veins; Cardiac Surgical Procedures; Cattle; Dyspnea; Echocardiography; Female; Heart Defects, Congenital; Heart Septal Defects, Atrial; Humans; Missed Diagnosis; Pulmonary Veins; Reoperation; Scimitar Syndrome; Tomography, X-Ray Computed; Vena Cava, Superior; adolescent; adverse event; animal; aorta; bovine; brachiocephalic vein; case report; congenital heart malformation; diagnostic imaging; dyspnea; echocardiography; female; heart septum defect; heart surgery; human; procedures; pulmonary vein; reoperation; scimitar syndrome; superior cava vein; x-ray computed tomography English 2021 2021-04-15 10.1186/s13019-021-01457-3 바로가기 바로가기 바로가기 바로가기
Article Open-wedge high tibial osteotomy in patients with discoid lateral meniscus Background: There are concerns about the progression of the lateral osteoarthritis (OA) should be taken into account when high tibial osteotomy (HTO) is performed in patients with discoid lateral meniscus (LM). This study evaluated the clinical results of HTO in patients with discoid LM and elucidated factors affecting the results. Methods: This study evaluated 32 female patients with varus deformity and medial OA. Patients with discoid LM (8 patients) or without discoid LM (24 patients) underwent open-wedge HTO. The mean age was 53.5 years and the mean follow-up period was 35 months. Clinical results, including the Hospital for Special Surgery (HSS) score, Knee Society knee score (KS) and function score (FS), were evaluated. The progression of OA in the lateral compartment was also evaluated. Finally, we evaluated the factors affecting the clinical results and OA progression in the lateral compartment. Results: Between two groups, all clinical scores were not different (p = 0.964, 0.963, and 0.559, respectively). Three of eight patients (37.5%) in the discoid group developed OA in the lateral compartment, whereas 2 of 24 patients (8.3%) in the control group developed such; however, this was not significantly different (p = 0.085). In discoid group, patients with undercorrection has higher KS relative to patients with acceptable correction (p = 0.044). Other clinical results and OA change in the lateral compartment were not affected by evaluated factors. Conclusions: Patients who underwent open-wedge HTO showed the satisfactory clinical results and lateral OA progression regardless of the presence or absence discoid LM. However, when discoid LM was present, patients with undercorrection showed higher KS in comparison with patients with acceptable correction. Kim, Hee-June; Shin, Ji-Yeon; Lee, Hyun-Joo; Jung, Chul-Hee; Park, Kyeong-Hyeon; Oh, Chang-Wug; Kyung, Hee-Soo Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthopaed Surg, 130 Dongduk Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Prevent Med, Daegu, South Korea ; Park, KyeongHyeon/KEH-4919-2024; Oh, Chang-Wug/AAO-4602-2021 36463735200; 55567961600; 58838750100; 57219314360; 56969984400; 22135834200; 7004292406 hskyung@knu.ac.kr; JOURNAL OF ORTHOPAEDIC SURGERY J ORTHOP SURG-HONG K 1022-5536 2309-4990 29 2 SCIE ORTHOPEDICS;SURGERY 2021 1.482 78.5 0.33 2025-07-30 2 2 discoid lateral meniscus; high tibial osteotomy; lateral compartment; varus deformity KNEE; OSTEOARTHRITIS; FIXATION discoid lateral meniscus; high tibial osteotomy; lateral compartment; varus deformity Female; Humans; Knee Joint; Menisci, Tibial; Middle Aged; Osteoarthritis, Knee; Osteotomy; Tibia; adult; Article; body mass; clinical article; controlled study; debridement; discoid lateral meniscus; female; follow up; hospital for special surgery score; human; knee arthroscopy; knee meniscus; knee society knee score; meniscectomy; middle aged; osteoarthritis; osteotomy; plate fixation; retrospective study; scoring system; tibia osteotomy; varus deformity; diagnostic imaging; knee; knee osteoarthritis; tibia English 2021 2021-05 10.1177/23094990211017355 바로가기 바로가기 바로가기 바로가기
Review Mesenchymal Stem Cell and MicroRNA Therapy of Musculoskeletal Diseases The therapeutic effects of mesenchymal stem cells (MSCs) in musculoskeletal diseases (MSDs) have been verified in many human and animal studies. Although some tissues contain MSCs, the number of cells harvested from those tissues and rate of proliferation in vitro are not enough for continuous transplantation. In order to produce and maintain stable MSCs, many attempts are made to induce differentiation from pluripotent stem cells (iPSCs) into MSCs. In particular, it is also known that the paracrine action of stem cell-secreted factors could promote the regeneration and differentiation of target cells in damaged tissue. MicroRNAs (miRNAs), one of the secreted factors, are small non-coding RNAs that regulate the translation of a gene. It is known that miRNAs help communication between stem cells and their surrounding niches through exosomes to regulate the proliferation and differentiation of stem cells. While studies have so far been underway targeting therapeutic miRNAs of MSDs, studies on specific miRNAs secreted from MSCs are still minimal. Hence, our ultimate goal is to obtain sufficient amounts of exosomes from iPSC-MSCs and develop them into therapeutic agents, furthermore to select specific miRNAs and provide safe cell-free clinical setting as a cell-free status with purpose of delivering them to target cells. This review article focuses on stem cell therapy on MSDs, specific microRNAs regulating MSDs and updates on novel approaches. Chung, Myung-Jin; Son, Ji-Yoon; Park, SunYoung; Park, Soon-Seok; Hur, Keun; Lee, Sang-Han; Lee, Eun-Joo; Park, Jin-Kyu; Hong, Il-Hwa; Kim, Tae-Hwan; Jeong, Kyu-Shik Kyungpook Natl Univ, Coll Vet Med, Dept Pathol, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Stem Cell Therapeut Res Inst, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Food Sci & Biotechnol, Daegu, South Korea Lee, Eun-Hye/KDN-5679-2024; Lee, Seung Eun/ABG-1607-2021; Hur, Keun/G-9513-2011; Chung, Myung/C-1876-2011; Jeong, Kyu-Shik/D-6740-2011 57193323993; 57211247483; 57085459500; 57224481584; 8861888000; 57221453703; 58363110000; 35213723500; 8702273100; 57202984578; 7201556460 jeongks@knu.ac.kr; INTERNATIONAL JOURNAL OF STEM CELLS INT J STEM CELLS 2005-3606 2005-5447 14 2 SCIE CELL & TISSUE ENGINEERING;CELL BIOLOGY 2021 3.011 78.7 0.88 2025-07-30 13 14 Mesenchymal stem cells; Induced pluripotent stem cells; Cell therapy; Musculoskeletal disorder; MicroRNA; Exosome UMBILICAL-CORD BLOOD; PLATELET-RICH PLASMA; BONE-MARROW; EXTRACELLULAR VESICLES; KNEE OSTEOARTHRITIS; INTRAARTICULAR INJECTION; ADIPOSE-TISSUE; SKELETAL-MUSCLE; STROMAL CELLS; OSTEOCHONDRAL DEFECTS Cell therapy; Exosome; Induced pluripotent stem cells; Mesenchymal stem cells; MicroRNA; Musculoskeletal disorder microRNA; Article; biological activity; bone marrow mesenchymal stem cell; cell differentiation; cell proliferation; exosome; hematopoietic stem cell; human; induced pluripotent stem cell; mesenchymal stem cell; mesenchymal stem cell transplantation; musculoskeletal disease; neural stem cell; nonhuman; stem cell niche; stem cell self-renewal; synovium English 2021 2021-05 10.15283/ijsc20167 바로가기 바로가기 바로가기 바로가기
Review Acute lower extremity arterial thrombosis after intraocular foreign body removal under general anesthesia: A case report and review of literature BACKGROUND Surgery, which is a major risk factor for venous thrombosis, has rarely been considered a risk factor for arterial thrombosis. Recent studies have suggested that venous and arterial thromboses share common risk factors and have a bidirectional relationship. Accordingly, there is a growing interest in the risk of arterial thrombosis after surgery. We report a case of acute bilateral lower extremity arterial thromboses that developed after a prolonged surgery. CASE SUMMARY A 59-year-old man was hospitalized for intraocular foreign body removal surgery. He was a heavy-drinking smoker and had untreated hypertension and varicose veins in both legs. The operation was unexpectedly prolonged, lasting 4 h and 45 min. Immediately after emergence from general anesthesia, the patient complained of extreme pain in both legs. After the surgical drape was removed, cyanosis was evident in both feet of the patient. The pulse was not palpable, and continuous-wave Doppler signals were inaudible in the bilateral dorsalis pedis and posterior tibial arteries. Computed tomography angiography confirmed acute bilateral thrombotic occlusion of the popliteal arteries, proximal anterior tibial arteries, and tibioperoneal trunks. Arterial pulse returned in both lower limbs after 6 h of heparin initiation. The patient was discharged on postoperative day 26 without any sequelae. CONCLUSION Acute lower extremity arterial thrombosis can occur after surgery. Anesthesiologists should pay particular attention to patients with risk factors for thrombosis. Jeon, Soeun; Hong, Jeong-Min; Lee, Hyeon Jeong; Kim, Eunsoo; Lee, Hyunju; Kim, Yesul; Ri, Hyun-Su; Lee, Jae Jung Pusan Natl Univ, Sch Med, Dept Anesthesia & Pain Med, 179 Gudeok Ro, Busan 49241, South Korea; Kyungpook Natl Univ, Sch Med, Dept Anesthesia & Pain Med, Daegu 41944, South Korea; Pusan Natl Univ, Coll Med, Dept Ophthalmol, Sch Med, Yangsan 50612, South Korea Hong, JeongMin/HSH-2481-2023; Kim, Eunsoo/AAJ-5077-2021 57190426433; 56883095200; 38061496500; 57202989732; 57192500799; 57223967367; 42462457900; 56799992200 ccarrot@pusan.ac.kr; WORLD JOURNAL OF CLINICAL CASES WORLD J CLIN CASES 2307-8960 9 27 SCIE MEDICINE, GENERAL & INTERNAL 2021 1.534 78.8 0 2025-07-30 0 0 Thromboembolism; Thrombosis; Arterial thrombosis; Arterial occlusive diseases; Peripheral occlusive artery disease; Case report PROTEIN-S-DEFICIENCY; VENOUS THROMBOEMBOLISM; RISK-FACTORS; ASSOCIATION; SMOKING; AGE Arterial occlusive diseases; Arterial thrombosis; Case report; Peripheral occlusive artery disease; Thromboembolism; Thrombosis antithrombin III; bilirubin; blood clotting factor 5 Leiden; brain natriuretic peptide; C reactive protein; creatine kinase; ephedrine; epidermal growth factor receptor; glycopyrronium; ketorolac; myoglobin; propofol; pyridostigmine; ramosetron; rocuronium; triacylglycerol; troponin; troponin I; adult; ankle brachial index; arterial wall thickness; artery thrombosis; Article; blood clot lysis; blood clotting time; breathing rate; case report; clinical article; computed tomographic angiography; computer assisted tomography; cyanosis; echography; electrocardiography; endotracheal intubation; eosinophil count; general anesthesia; glucose blood level; heart rate; human; intraocular foreign body; lower limb; male; middle aged; motor evoked potential; muscle strength; myocutaneous flap; neutrophil lymphocyte ratio; operation duration; oxygen saturation; pulse wave; renal protection; sinus rhythm; systolic blood pressure; transesophageal echocardiography; urea nitrogen blood level English 2021 2021-09-26 10.12998/wjcc.v9.i27.8232 바로가기 바로가기 바로가기 바로가기
Article MIMO/Diversity Antenna with Neutralization Line for WLAN Applications A four-port multi-input-multi-output (MIMO) antenna is designed for the WLAN access point applications. The prospective antenna consists of four double-layered printed dipole antennas (DLPDAs), where two elements are designed to resonate at a frequency of 2.45 GHz and the resonant frequency of the other two elements is 5.8 GHz. The resonant bandwidths of the DLPDAs are 24.7% (2.09-2.68 GHz) and 28.9% (4.73-6.33 GHz) at 2.45 GHz and 5.8 GHz, respectively. The proposed MIMO antenna is printed on the FR-4 substrate of size 45 mm x 60 mm x 1.6 mm. A decoupling network is introduced in the center of the proposed antenna to achieve high isolation between resonating elements. The decoupling arrangement is a combination of four metal strips and a circular loop that acts as a neutralization line. It opposes the direct coupling current and provides isolation of around 20.55 dB at 2.45 GHz and 33.08 dB at 5.8 GHz. Birwal, A.; Singh, S.; Kanaujia, B. K.; Kumar, S. Univ Delhi, Dept Elect Sci, South Campus, New Delhi 110022, India; Univ Delhi, Inst Informat & Commun, South Campus, New Delhi 110022, India; Jawaharlal Nehru Univ, Sch Computat & Integrat Sci, New Delhi 110067, India; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea Kumar, Sachin/W-2211-2019; kanaujia, Binod/L-6484-2019; Singh, Siddhartha/G-5396-2012; Kanaujia, Binod/L-6484-2019 57201942774; 57216140046; 56962785800; 56907994000 gupta.sachin0708@gmail.com; MAPAN-JOURNAL OF METROLOGY SOCIETY OF INDIA MAPAN-J METROL SOC I 0970-3950 0974-9853 36 4 SCIE INSTRUMENTS & INSTRUMENTATION;PHYSICS, APPLIED 2021 1.446 78.9 1.8 2025-07-30 19 21 Dipole antenna; Diversity; MIMO; Neutralization line MUTUAL COUPLING REDUCTION; MONOPOLE ANTENNA Dipole antenna; Diversity; MIMO; Neutralization line English 2021 2021-12 10.1007/s12647-020-00427-9 바로가기 바로가기 바로가기 바로가기
Article Prognostic Factors of Second-line Immune Checkpoint Inhibitors in Patients With Advanced-stage Non-Small Cell Lung Cancer A Multicenter, Retrospective Study Objectives: Immune checkpoint inhibitors (ICIs) targeting the programmed cell death receptor-1 and its ligand have achieved impressive success in treating patients with advanced-stage non-small cell lung cancer (NSCLC) after failed first-line cytotoxic chemotherapy. However, knowledge on clinical biomarkers that could help select patients who will respond well to second-line ICI therapy is limited. Patients and Methods: Medical records of patients with NSCLC treated with first-line platinum-based chemotherapy and subsequent second-line ICI were collected from 6 medical centers between January 2018 and June 2020. Clinical information, pathologic variables, and radiologic findings of the data collected were reviewed. The patients were followed up until the date of the last visit, the death of any cause, or the end of data recording (December 31, 2020). Results: A total of 181 patients with NSCLC were treated with second-line ICI following first-line platinum-based doublet chemotherapy. The median progression-free survival was 2.0 months (interquartile range, 1.0 to 5.5 mo), and the median overall survival was 12.0 months (interquartile range, 6.0 to 20.0 mo). Low body mass index (BMI) was independently associated with progression-free survival (odds ratio [OR], 0.826; 95% confidence interval [CI], 0.723-0.945; P=0.005). Similarly, a low BMI (OR, 0.839; 95% CI, 0.740-0.952; P=0.005) and a high number of metastatic organs (OR, 1.682; 95% CI, 1.156-2.448; P=0.007) were independently associated with the overall survival after second-line ICI therapy. Conclusion: BMI and the number of metastatic sites were significantly associated with second-line ICI therapy outcomes in patients with NSCLC receiving first-line platinum-based chemotherapy. Roh, Jiyeon; Eom, Jung Seop; Lee, Min Ki; Kim, Jehun; Jang, Taewon; Yoon, Seong Hoon; Son, Choon-Hee; Lee, Hyun-Kyung; Kim, Hyun-Kuk; Lee, Shin Yup; Shin, Kyeong Choel; Kim, Mi-Hyun Pusan Natl Univ, Sch Med, Dept Internal Med, Busan, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Kosin Univ, Gospel Hosp, Dept Pulmonol, Busan, South Korea; Dong A Univ Hosp, Busan, South Korea; Inje Univ, Busan Paik Hosp, Busan, South Korea; Inje Univ, Haeundae Paik Hosp, Busan, South Korea; Yangsan Pusan Natl Univ Hosp, Yangsan Si, Gyeongsangnam P, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Daegu, South Korea; Yeungnam Univ Hosp, Daegu, South Korea Kim, Young-Il/ISS-7678-2023; Kim, Woo/A-8216-2019 57204679207; 57201262394; 16433227400; 57191899861; 7102426031; 55479240500; 7005976988; 57835046800; 57216619509; 49863712700; 35320479500; 26323727500 jiyeonroh@nate.com;ejspulm@gmail.com;leemk@pusan.ac.kr;libertier@gmail.com;jangtw22@hanmail.net;drysh79@gmail.com;son30243@hanmail.net;goodoc@gmail.com;khkmd1205@hanmail.net;shinyup@knu.ac.kr;shin1014@ynu.ac.kr;mihyunkim@pusan.ac.kr; AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS AM J CLIN ONCOL-CANC 0277-3732 1537-453X 44 7 SCIE ONCOLOGY 2021 2.787 79.0 0.14 2025-07-30 2 2 clinical biomarkers; progression-free survival; metastatic sites; doublet chemotherapy; lung cancer CHEMOTHERAPY clinical biomarkers; doublet chemotherapy; lung cancer; metastatic sites; progression-free survival Aged; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Carcinoma, Non-Small-Cell Lung; Female; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Male; Middle Aged; Progression-Free Survival; Retrospective Studies; Treatment Outcome; antineoplastic metal complex; atezolizumab; gemcitabine; nivolumab; paclitaxel; pembrolizumab; pemetrexed; antineoplastic agent; adult; advanced cancer; aged; Article; body mass; cancer chemotherapy; cancer patient; cancer prognosis; cancer staging; cancer survival; controlled study; doublet chemotherapy; female; human; major clinical study; male; non small cell lung cancer; obesity; overall survival; progression free survival; retrospective study; risk factor; underweight; clinical trial; lung tumor; middle aged; mortality; multicenter study; non small cell lung cancer; pathology; treatment outcome English 2021 2021-07 10.1097/coc.0000000000000828 바로가기 바로가기 바로가기 바로가기
Article Effect of Everolimus with Low-Dose Tacrolimus on Development of New-Onset Diabetes After Transplantation and Allograft Function in Kidney Transplantation: A Multicenter, Open-Label, Randomized Trial Background: This randomized controlled trial aimed to investigate the effect of everolimus (EVL) with low-dose tacrolimus (Tac) on the development of post-transplantation diabetes mellitus (PTDM) in kidney transplantation (KT). Material/Methods: Seventy-seven kidney transplant patients from 4 transplant centers were included. Patients were randomized to the "EVL group" (n=38) and the "TAC group" (n=39). The target Tac trough level was 2 to 5 ng/mL in the EVL group and 5 to 10 ng/mL in the TAC group. Results: The 1-year cumulative incidence of PTDM in all patients was 7.8%, and no difference was found between the 2 groups (P=0.0819). Insulin resistance measured with the homeostatic model assessment for insulin resistance showed a significant increase only in the TAC group (1.11 to 1.30, P=0.0492). Allograft rejection rate and estimated glomerular filtration rate (eGFR) follow-ups every 3 months were not significantly different between the 2 groups. However, the EVL group showed a significant increase in the mean eGFR at 9 months and 12 months after KT compared to the baseline value (P=0.0242 and 0.0491, respectively). The EVL group showed lower insulin resistance and higher allograft function in comparison to the TAC group. Conclusions: EVL-based immunosuppressive therapy with lower Tac exposure could be a safer alternative for maintenance treatment. Kim, Hyung Duk; Chang, Ji-Yeun; Chung, Byung Ha; Kim, Chan-Duck; Lee, Sang-Ho; Kim, Yeong Hoon; Yang, Chul Woo Catholic Univ Korea, Dept Internal Med, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Internal Med, Sch Med, Daegu, South Korea; Kyung Hee Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Inje Univ, Dept Internal Med, Coll Med, Pusan, South Korea ; Kim, Hyungduk/CAH-5630-2022; Kim, Tae-Hee/AAN-9079-2021 56115122100; 56011421700; 57201863822; 8558530700; 55890136000; 7410196419; 7407743404 yangch@catholic.ac.kr; ANNALS OF TRANSPLANTATION ANN TRANSPL 1425-9524 26 SCIE SURGERY;TRANSPLANTATION 2021 1.479 79.1 1.46 2025-07-30 14 13 Diabetes Mellitus; Graft Rejection; Kidney Transplantation TERM GRAFT-SURVIVAL; RENAL-TRANSPLANTATION; CALCINEURIN INHIBITORS; MYCOPHENOLATE-MOFETIL; PATIENT SURVIVAL; EARLY CONVERSION; MTOR INHIBITORS; CYCLOSPORINE; RECIPIENTS; MELLITUS Diabetes Mellitus; Graft Rejection; Kidney Transplantation azathioprine; bilirubin; estradiol; everolimus; high density lipoprotein cholesterol; low density lipoprotein cholesterol; mycophenolate mofetil; mycophenolic acid; myrept; panel reactive antibody; tacrolimus; thymocyte antibody; triacylglycerol; adult; Article; bleeding disorder; blood sampling; chickenpox; cholesterol blood level; controlled study; creatinine blood level; cumulative incidence; diabetes mellitus; diarrhea; drug dose increase; estimated glomerular filtration rate; female; fibrocystic breast disease; gastroenteritis; graft recipient; graft survival; hemodialysis; herpes zoster; high density lipoprotein cholesterol level; HOMA index; homeostasis model assessment; hospitalization; human; immunosuppressive treatment; influenza; insulin resistance; kidney biopsy; kidney function; kidney graft; kidney transplantation; low density lipoprotein cholesterol level; low drug dose; maintenance therapy; male; microalbuminuria; multicenter study; neoplasm; oral glucose tolerance test; outcome assessment; patient compliance; proteinuria; randomized controlled trial; risk factor; ureter stone; urinary tract infection; virus meningitis English 2021 2021-01-22 10.12659/aot.927984 바로가기 바로가기 바로가기 바로가기
Article Apoptosis-like death-inducing property of tachyplesin I in Escherichia coli Antimicrobial peptide (AMP) derived from the horseshoe crab, tachyplesin I (KWCFRVCYRGICYRRCR-NH2), displayed the apparent antimicrobial activity with low cytotoxicity, suggesting its efficacy as an attractive agent but still lacks the understandings regarding its mechanism(s). Hence, the study focused on investigating the antibacterial mode of action of tachyplesin I against Escherichia coli. Based on the reactive oxygen species generation displayed in several antimicrobial effects, the detection of superoxide anion and nitric oxide were verified after tachyplesin I treatment. Substantial increment of two molecules was followed by the imbalance in intracellular ion concentration, noticeably magnesium and calcium. The series of stages led to hydroxyl radical generation with reduced glutathione, followed by damage in DNA due to oxidative stress. Eventually, the apoptosis-like death in E. coli was monitored in DNA fragmentation-dependent manner due to the tachyplesin I treatment, verified by membrane depolarization, caspase-like protein activation, and phosphatidylserine exposure. Accordingly, tachyplesin I induces apoptosis-like death in E. coli, suggesting the potential of being a candidate for regulating bacterial infection. Kwun, Min Seok; Lee, Dong Gun Kyungpook Natl Univ, Sch Life Sci, BK 21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea Lee, Dong-Gun/IWD-9833-2023 57212491555; 55668060900 dglee222@knu.ac.kr; JOURNAL OF BASIC MICROBIOLOGY J BASIC MICROB 0233-111X 1521-4028 61 9 SCIE MICROBIOLOGY 2021 2.65 79.2 0.39 2025-07-30 4 4 antimicrobial peptide; apoptosis-like death; Escherichia coli; tachyplesin HYDROXYL RADICAL PRODUCTION; ANTIMICROBIAL PEPTIDE; NITRIC-OXIDE; CANDIDA-ALBICANS; MAGNESIUM; MEMBRANE; DAMAGE; GLUTATHIONE; MECHANISM; BACTERIAL antimicrobial peptide; apoptosis-like death; Escherichia coli; tachyplesin Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Antimicrobial Peptides; Apoptosis; DNA Damage; DNA-Binding Proteins; Escherichia coli; Nitric Oxide; Peptides, Cyclic; Reactive Oxygen Species; antiinfective agent; antimicrobial cationic peptide; cyclopeptide; DNA binding protein; nitric oxide; polypeptide antibiotic agent; reactive oxygen metabolite; tachyplesin peptide, Tachypleus tridentatus; apoptosis; DNA damage; drug effect; Escherichia coli English 2021 2021-09 10.1002/jobm.202100133 바로가기 바로가기 바로가기 바로가기
Article Characterization of Pestalotiopsis sp. causing gray leaf spot in coconut (Cocos nucifera L.) in Bangladesh Coconut (Cocos nucifera L.) is one of the most important fruit trees in Bangladesh. This tree is susceptible to various pathogens. Among them, a fungus was consistently isolated from gray leaf spot symptom in coconut. This study aimed to isolate, characterize, and find the management strategies of the causal fungus of gray leaf spot disease in coconut. Both morphological and molecular characters identified the pathogen as Pestalotiopsis sp. for the first time in Bangladesh. Artificial inoculation of this fungus showed symptoms similar to those previously observed in the field. Cross-inoculation test suggests that Pestalotiopsis sp. has a wide host range. The infection process of Pestalotiopsis sp. started at 2 h after inoculation (hai) with the formation of germ tube followed by the formation of infection hyphae, which penetrated directly into the host at 6 hai. Gray leaf spot symptom was developed at 120 hai. Numerous conidia developed from the acervuli at 168 hai. These conidia acted as the source of inocula for secondary infection. The optimum temperature for the growth of Pestalotiopsis sp. was 25 degrees C, however, the growth of Pestalotiopsis sp. ceased at 15 degrees C and 35 degrees C. This pathogen was completely inhibited by Autostin 50 WDG (carbendazim) at 100 ppm. Trichoderma viride (Pb-7) was found as the potential biocontrol agent against Pestalotiopsis sp. These findings could contribute to describing the disease cycle and epidemiology of Pestalotiopsis sp. that would ultimately require to undertake effective control measures against this pathogen. Bhuiyan, Md. Abdullahil Baki; Sultana, Nasrin; Mahmud, Nur U.; Kader, Md. Abdul; Hassan, Oliul; Chang, Taehyun; Islam, Tofazzal; Akanda, Abdul M. Bangabandhu Sheikh Mujibur Rahman Agr Univ, Dept Plant Pathol, Gazipur 1706, Bangladesh; Bangabandhu Sheikh Mujibur Rahman Agr Univ, Inst Biotechnol & Genet Engn IBGE, Gazipur 1706, Bangladesh; Kyungpook Natl Univ, Dept Ecol Environm Syst, Coll Ecol Environm Sci, Daegu, South Korea Islam, Tofazzal/C-9184-2013; Mahmud, Nur Uddin/GLS-0486-2022; Islam, Tofazzal/F-2563-2010 57217846776; 57249896200; 57206365083; 57194525347; 12762464400; 55301101700; 58402647300; 23476498000 baki@bsmrau.edu.bd;tofazzalislam@bsmrau.edu.bd; JOURNAL OF BASIC MICROBIOLOGY J BASIC MICROB 0233-111X 1521-4028 61 12 SCIE MICROBIOLOGY 2021 2.65 79.2 0.96 2025-07-30 7 13 conidia; infection process; integrated disease management; internal transcribed spacer; leaf disease; Pestalotiopsis 1ST REPORT; PHYLOGENIES; MANGIFERAE; DIVERSITY; SPP. conidia; infection process; integrated disease management; internal transcribed spacer; leaf disease; Pestalotiopsis Bangladesh; Cocos; Fruit; Pestalotiopsis; Plant Diseases; Bangladesh; coconut; fruit; plant disease English 2021 2021-12 10.1002/jobm.202100253 바로가기 바로가기 바로가기 바로가기
Article Evaluation of residual strength with ultrasonic pulse velocity relationship for concrete exposed to high temperatures This paper presents the results of an experimental investigation on the relationship between strength and ultrasonic pulse velocity (UPV) of concrete exposed to high temperature, especially for a decision of building remodeling of concrete structures. The experiments were conducted at three different initial compressive strength levels for temperature up to 800 degrees C. UPV, Compressive, and splitting tensile tests and UPV measurements were performed for unheated and heated concrete specimens. The measured UPV values in the present work were correlated with compressive and tensile strengths to estimate the strength of concrete. Based on the results, two linear equations for predicting compressive and tensile strength of concrete at elevated temperatures using UPV have been proposed. It is found that the difference of initial compressive strength of concrete does not have a significant effect on the strength reduction ratio after exposed to high temperatures. In addition, the reduction factors of compressive and tensile strengths in the present work do not well comply with the values of suggested by EN 1992-1-2. Choi, Yeol; Kang, Joo-Won; Hwang, Tae-Yeon; Cho, Chang-Geun Kyungpook Natl Univ, Sch Architecture, Daegu, South Korea; Yeung Nam Univ, Sch Architecture, Kyungsan, South Korea; Chosun Univ, Architectural Engn, Philmundaero 309, Gwangju 61452, South Korea 14519187800; 26432048700; 57271661900; 24722559700 chocg@chosun.ac.kr; ADVANCES IN MECHANICAL ENGINEERING ADV MECH ENG 1687-8132 1687-8140 13 9 SCIE ENGINEERING, MECHANICAL;THERMODYNAMICS 2021 1.566 79.2 0.41 2025-07-30 11 13 Ultrasonic pulse velocity; reduction factor; concrete strength; regression; high temperature COMPRESSIVE STRENGTH concrete strength; high temperature; reduction factor; regression; Ultrasonic pulse velocity English 2021 2021-09 10.1177/16878140211034992 바로가기 바로가기 바로가기 바로가기
Article A high basal metabolic rate is an independent predictor of stone recurrence in obese patients Purpose: Basal metabolic rate (BMR) is an indicator of overall body metabolism and may portend unique aberrations in urine physico-chemistry and stone recurrence. The present study examined the effect of predicted BMR on 24 hours urinary metabolic profiles and stone recurrence in obese stone patients. Materials and Methods: Data from 308 obese patients (body mass index [BMI] >= 30 kg/m(2)) diagnosed with urinary stone disease between 2003 and 2015 were analyzed retrospectively. BMR was calculated using the Harris-Benedict equation, and patients were classified into two predicted BMR categories (= 1,145 kcal/day). Urinary metabolic parameters and risk of stone recurrence were compared between the two groups. Results: The high BMR group was more likely to be younger and female, and to have a high BMI and lower incidence of diabetes than the low BMR group (each p<0.05). There was a positive correlation between BMR and 24 hours urinary sodium, uric acid, and phosphate excretion. The amounts of stone-forming constituents such as calcium and uric acid were significantly higher in the high BMR group. Kaplan-Meier estimates showed that the high BMR group had a significantly shorter stone recurrence-free period than the low BMR group (log-rank test, p<0.001). Multivariate Cox regression analyses revealed that predicted BMR was an independent factor of stone recurrence (hazard ratio, 2.759; 95% confidence interval, 1.413-5.386; p=0.003). Conclusions: BMR may be an easily measured parameter that can be used to identify risk of stone recurrence in obese stone patients. Kang, Ho Won; Seo, Sung Pil; Lee, Hee Youn; Kim, Kyeong; Ha, Yun-Sok; Kim, Won Tae; Kim, Yong-June; Yun, Seok-Joong; Kim, Wun-Jae; Lee, Sang-Cheol Chungbuk Natl Univ, Dept Urol, Coll Med, 776,1sunhwan Ro, Cheongju 28644, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea Lee, Sang/E-4151-2012; Kim, Sung-Soo/AFP-2188-2022; Kim, Kyu/E-7814-2012; Kim, Jae-hyung/J-8504-2012; Kim, Yong-June/E-5622-2012 35757703900; 56115644100; 57217589965; 57220864860; 35487226400; 57203514393; 26422204800; 16302421300; 8081691400; 57218216917 lscuro@chungbuk.ac.kr; INVESTIGATIVE AND CLINICAL UROLOGY INVESTIG CLIN UROL 2466-0493 2466-054X 62 2 SCIE UROLOGY & NEPHROLOGY 2021 1.902 79.4 1.03 2025-07-30 6 7 Basal metabolism; Obesity; Recurrence; Urinary calculi RISK; OVERWEIGHT; IMPACT; AGE; UROLITHIASIS; ASSOCIATION; DISEASE Basal metabolism; Obesity; Recurrence; Urinary calculi Adult; Basal Metabolism; Female; Humans; Male; Middle Aged; Obesity; Recurrence; Retrospective Studies; Urinary Calculi; calcium; calcium oxalate; calcium phosphate; citric acid; magnesium; oxalic acid; uric acid; adult; Article; basal metabolic rate; body mass; cohort analysis; computer assisted tomography; diabetes mellitus; echography; female; Fourier transform infrared spectroscopy; human; hypertension; major clinical study; male; nephrolithiasis; obese patient; phosphate excretion; radiology; receiver operating characteristic; recurrent disease; retrospective study; sodium urine level; underweight; urolithiasis; complication; metabolism; middle aged; obesity; recurrent disease; urolithiasis English 2021 2021-03 10.4111/icu.20200438 바로가기 바로가기 바로가기 바로가기
Article Efficacy and safety of modified tract dilation technique using simultaneous pulling of proximal and distal ends of a guidewire for percutaneous nephrolithotomy in modified supine position Purpose: Recently, the needs for supine percutaneous nephrolithotomy (PCNL) have become more increased because of an easy approach for endoscopic combined intrarenal surgery. However, making a nephrostomy tract during supine PCNL is more difficult than prone position due to movable kidney. To overcome this limitation, we used a modified nephrostomy tract dilation (MTD) technique using guidewire traction. Materials and Methods: From January 2014 to June 2019, a total of 259 patients underwent PCNL in the modified supine position. Among them, the MTD technique was performed in 171 patients. For the MTD technique, two hydrophilic guidewires were passed from the nephrostomy tract and brought out through the urethra, then both proximal and distal ends were contralaterally pulled with tension for the easy placement of a fascia-cutting needle and a balloon catheter. We analyzed the efficacy of this technique in comparison with the conventional method. Results: Intraoperative radiation exposure time (RET) (68.87 vs. 212.11 s) and hospital stay (5.90 vs. 6.74 days) were significantly shorter, while the success rate (77.2% vs. 63.6%) was significantly higher in the MTD group. Multivariate analysis showed that only the maximal stone diameter (odds ratio [OR], 1.928; 95% confidence interval [CI], 1.314-2.828; p=0.001) and MTD technique (OR, 0.017; 95% CI, 0.007-0.040; p<0.001) were independent factors for predicting short RET (<120 s). Conclusions: This study demonstrated that MTD technique can be effectively and safely performed in modified supine position PCNL, and it can be helpful in reducing RET and enhancing success rates. Chung, Jae Wook; Ha, Heon; Park, Dong Jin; Ha, Yun Sok; Lee, Jun Nyung; Chun, So Young; Kwon, Tae Gyun; Kim, Bum Soo Kyungpook Natl Univ, Dept Urol, Chilgok Hosp, Daegu, South Korea; Pohang Semyeong Christianity Hosp, Dept Urol, Pohang, South Korea; Dongguk Univ, Gyeongju Hosp, Dept Urol, Coll Med, Gyeongju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ Hosp, BioMed Res Inst, Joint Inst Regenerat Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Urol, 130 Dongdeok Ro, Daegu 41944, South Korea ; Kim, Soo-Yeon/ADR-9663-2022 35204798500; 57211608305; 57220636322; 35487226400; 16301364600; 8688166900; 15073765400; 57202817150 urokbs@knu.ac.kr; INVESTIGATIVE AND CLINICAL UROLOGY INVESTIG CLIN UROL 2466-0493 2466-054X 62 2 SCIE UROLOGY & NEPHROLOGY 2021 1.902 79.4 1.18 2025-07-30 9 11 Kidney calculi; Nephrolithotomy; percutaneous; Nephrostomy STONE-FREE RATE; MORBIDLY OBESE; PRONE POSITION; ANTEROGRADE; LITHOTOMY; VALDIVIA; STANDARD Kidney calculi; Nephrolithotomy, percutaneous; Nephrostomy Adult; Aged; Dilatation; Female; Humans; Male; Middle Aged; Nephrolithotomy, Percutaneous; Patient Positioning; Retrospective Studies; Supine Position; Treatment Outcome; adult; ankylosis; Article; blood transfusion; computer assisted tomography; cystoscopy; false aneurysm; female; flow-mediated dilation test; human; kidney calyx; kidney pelvis; lithotripsy; major clinical study; male; nephrolithiasis; nephrostomy; operation duration; percutaneous nephrolithotomy; postoperative complication; radiation exposure; retrospective study; safety; sensitivity and specificity; spastic paraplegia; staghorn stone; supine position; therapeutic index; ureteropelvic junction; urinary tract infection; adverse event; aged; devices; dilatation; middle aged; patient positioning; percutaneous nephrolithotomy; procedures; supine position; treatment outcome English 2021 2021-03 10.4111/icu.20200276 바로가기 바로가기 바로가기 바로가기
Article Expression of phosphorylated p21-activated kinase 4 is associated with aggressive histologic characteristics and poor prognosis in patients with surgically treated renal cell carcinoma Purpose: P21-activated kinase 4 (PAK4), a serine/threonine kinase that regulates a number of fundamental cellular processes, has been suggested as a prognostic factor for various human tumors. The aim of the present study was to evaluate the clinical implications of phospho-Ser474 PAK4 (pPAK4(S474)), an activated form of PAK4, in surgically treated renal cell carcinoma (RCC). Materials and Methods: Samples from 131 patients with surgically treated RCC were immunostained to detect PAK4 and pPAK4(S474). Expression of PAK4 and pPAK4(S474) was compared with clinicopathological characteristics and survival after nephrectomy. Results: PAK4 and pPAK4(S474) were expressed predominantly in the nucleus. Overall, 57.3% (75/131) and 24.4% (29/119) of specimens exhibited high expression of pPAK4(S474) and PAK4, respectively. High expression of pPAK4(S474) was associated with adverse pathologic characteristics, including advanced tumor stage and grade (p=0.036 and p=0.002, respectively), whereas this association was not significant for PAK4 expression (each p>0.05). Kaplan-Meier estimates showed that high expression of pPAK4(S474) was associated with shorter recurrence-free survival in a subgroup with localized RCC and with cancer-specific survival in the total RCC cohort (log-rank test: p=0.001 and p=0.005, respectively), whereas PAK4 expression was not. Multivariate Cox regression analysis identified that high pPAK4(S474) expression was an independent predictor of recurrence in the subgroup with localized RCC. Conclusions: pPAK4(S474) may be a more accurate prognostic factor than total PAK4 in RCC patients. This marker would be useful for identifying patients with pathologically localized disease who may require further interventions. Kang, Ho Won; Piao, Xuan Mei; Lee, Hee Youn; Kim, Kyeong; Seo, Sung Pil; Ha, Yun-Sok; Kim, Yeong Uk; Kim, Won Tae; Kim, Yong-June; Lee, Sang-Cheol; Kim, Wun-Jae; Shin, Eun-Young; Kim, Eung-Gook; Yun, Seok Joong Chungbuk Natl Univ, Chungbuk Natl Univ Hosp, Coll Med, Dept Urol, Cheongju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Yeungnam Univ, Sch Med, Dept Urol, Daegu, South Korea; Chungbuk Natl Univ, Coll Med, Dept Biochem, 776,1sunhwan-ro, Cheongju 28644, South Korea; Chungbuk Natl Univ, Coll Med, Med Res Ctr, 776,1sunhwan-ro, Cheongju 28644, South Korea Kim, Sung-Soo/AFP-2188-2022; Piao, Xuan-Mei/ABI-6955-2020; Lee, Sang/E-4151-2012; Kim, Jae-hyung/J-8504-2012; Kim, Yong-June/E-5622-2012; Kim, Kyu/E-7814-2012; Kim, Young-Il/ISS-7678-2023; KIM, EUNG-GOOK/IVH-4093-2023 35757703900; 57188653344; 57217589965; 57220864860; 56115644100; 35487226400; 56678184600; 57203514393; 26422204800; 57218216917; 8081691400; 7202356339; 7404506135; 16302421300 egkim@chungbuk.ac.kr;sjyun@chungbuk.ac.kr; INVESTIGATIVE AND CLINICAL UROLOGY INVESTIG CLIN UROL 2466-0493 2466-054X 62 4 SCIE UROLOGY & NEPHROLOGY 2021 1.902 79.4 0.44 2025-07-30 5 5 P21-activated kinase 4; Recurrence; Renal cell carcinoma; Survival GUIDELINES; BIOLOGY P21-activated kinase 4; Recurrence; Renal cell carcinoma; Survival Aged; Carcinoma, Renal Cell; Cell Nucleus; Cytoplasm; Female; Humans; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; p21-Activated Kinases; Phosphorylation; Prognosis; Proportional Hazards Models; Survival Rate; creatinine; p21 activated kinase 4; threonine; p21 activated kinase; PAK4 protein, human; adult; Article; body mass; cancer prognosis; cancer recurrence; cancer specific survival; cancer staging; cancer survival; clinical evaluation; enzyme activity; female; gene expression; human; human tissue; hypertension; immunohistochemistry; Kaplan Meier method; log rank test; lymph node metastasis; major clinical study; male; middle aged; nephrectomy; overall survival; partial nephrectomy; prospective study; protein expression; recurrence free survival; renal cell carcinoma; retrospective study; transurethral resection; tumor volume; aged; cancer grading; cell nucleus; cytoplasm; kidney tumor; metabolism; pathology; phosphorylation; prognosis; proportional hazards model; renal cell carcinoma; survival rate; tumor recurrence English 2021 2021-07 10.4111/icu.20200399 바로가기 바로가기 바로가기 바로가기
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WOS Citation Web of Science에서 집계된 해당 논문의 총 인용 횟수입니다.
SCOPUS Citation SCOPUS에서 집계된 해당 논문의 총 인용 횟수입니다.
Keywords (WoS) 저자가 논문에서 직접 지정한 키워드입니다. Web of Science에 등록된 저자 키워드 목록입니다.
KeywordsPlus (WoS) Web of Science에서 자동으로 추출한 추가 키워드입니다. 논문의 참고문헌 제목에서 자주 등장하는 단어들로 생성됩니다.
Keywords (SCOPUS) 저자가 논문에서 직접 지정한 키워드입니다. SCOPUS에 등록된 저자 키워드 목록입니다.
KeywordsPlus (SCOPUS) SCOPUS에서 자동으로 추출하거나 추가한 색인 키워드입니다.
Language 논문이 작성된 언어입니다. 대부분 English이며, 그 외 다양한 언어로 작성된 논문이 포함될 수 있습니다.
Publication Year 논문이 출판된 연도입니다.
Publication Date 논문의 정확한 출판 날짜입니다 (년-월-일 형식).
DOI Digital Object Identifier. 디지털 객체 식별자로, 논문을 고유하게 식별하는 영구적인 식별번호입니다. 이를 통해 논문의 온라인 위치를 찾을 수 있습니다.