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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Tribological characteristics of a microtextured polymer fabricated via an additive manufacturing process | With the growing interest in 3D printing, many studies are being conducted to replace conventional manufacturing processes. In terms of mechanical applications, however, research on the tribological characteristics of 3D printing components has not been sufficiently conducted. This study investigated the influences of surface texturing and roughness on 3D printed specimens. Specimens with and without surface texture were printed using a 3D printer, and their frictional behavior was compared. The friction coefficient of the textured specimen was smaller than that of the untextured specimen. Contact analysis was conducted to evaluate the mechanism. The analysis suggested that the real contact area of the untextured specimen was similar to that of the textured specimen during the initial stage. However, the wear of asperities during the friction test increased the real contact area of the untextured specimen. Surface roughness was verified to influence the untextured specimen more significantly than the textured specimen in terms of tribological behavior. | Lee, Sang-Hoon; Kim, Tae-Wook; Kim, Hyun-Joon | Kyungpook Natl Univ, Dept Adv Sci & Technol Convergence, Sangju 37224, South Korea; Kyungpook Natl Univ, Dept Precis Mech Engn, Sangju 37224, South Korea | 56812964000; 57030752600; 56766313200 | hjoonkim@knu.ac.kr; | JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY | J MECH SCI TECHNOL | 1738-494X | 1976-3824 | 36 | 8 | SCIE | ENGINEERING, MECHANICAL | 2022 | 1.6 | 75.4 | 0.16 | 2025-06-25 | 1 | 2 | Additive manufacturing; Contact analysis; Friction; Microtexture; Surface design | TEXTURED SURFACES; FRICTION; PERFORMANCE; CONTACT; BEHAVIOR; WEAR | Additive manufacturing; Contact analysis; Friction; Microtexture; Surface design | 3D printers; Additives; Surface roughness; Textures; Tribology; 3-D printing; 3D-printing; Additive manufacturing process; Contact analysis; Conventional manufacturing; Manufacturing process; Micro-texture; Real contact area; Surface design; Tribological characteristics; Friction | English | 2022 | 2022-08 | 10.1007/s12206-022-0734-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A risk scoring system to predict clinical events in chronic hepatitis B virus infection: A nationwide cohort study | Many patients with chronic hepatitis B do not receive adequate follow-up. This study aimed to develop a risk score to predict clinical events in patients with chronic hepatitis B virus (HBV) infection at the population level for identifying patients at high risk to warrant regular follow-up. This study analysed population-based data from the nationwide claims database of South Korea obtained between 2005 and 2015. We identified 507,239 non-cirrhotic patients with chronic HBV infection who are not under antiviral treatment. A risk score for predicting clinical events (hepatocellular carcinoma, death or liver transplantation) was developed based on multivariable Cox proportional hazard model in a development cohort (n = 401,745) and validated in a validation cohort (n = 105,494). The cumulative incidence rates of clinical events at 5 years were 2.56% and 2.44% in the development and validation cohorts, respectively. Clinical events in asymptomatic patients with chronic HBV infection (CAP-B) score ranging from 0 to 7.5 points based on age, sex, socioeconomic status, chronic hepatitis C co-infection, diabetes mellitus, statin or antiplatelet exposure, smoking, alcohol consumption, alanine aminotransferase and gamma-glutamyltransferase had good discriminatory accuracy in both the development and validation cohorts (c-indices for 3-, 5- and 10-year risk prediction: all 0.786). The predicted and observed probabilities of clinical events were calibrated in both cohorts. A score of >3.5 points identified subjects at distinctly high risk. The CAP-B score using easily accessible variables can predict clinical events and may allow selection of patients with chronic HBV infection for priority of regular follow-up. | Jo, Ae Jeong; Choi, Won-Mook; Kim, Hyo Jeong; Choi, So Hyun; Han, Seungbong; Ko, Min Jung; Lim, Young-Suk | Natl Evidence Based Healthcare Collaborating Agcy, Div Healthcare Technol Assessment Res, 173 Toegye Ro, Seoul 04554, South Korea; Univ Ulsan, Liver Ctr, Asan Med Ctr, Dept Gastroenterol,Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Korea Univ, Dept Biostat, Coll Med, Seoul, South Korea | Choi, Won-Mook/ABE-2662-2021; Lim, Young-Suk/AFQ-5165-2022 | 57190185428; 57203486081; 57476930200; 57217007802; 54885771000; 56727527900; 57226548822 | minjung.ko@neca.re.kr;limys@amc.seoul.kr; | JOURNAL OF VIRAL HEPATITIS | J VIRAL HEPATITIS | 1352-0504 | 1365-2893 | 29 | 2 | SCIE | GASTROENTEROLOGY & HEPATOLOGY;INFECTIOUS DISEASES;VIROLOGY | 2022 | 2.5 | 75.5 | 0.47 | 2025-06-25 | 4 | 5 | death; hepatocellular carcinoma; liver transplantation; national health insurance database; risk prediction | HEPATOCELLULAR-CARCINOMA RISK; POPULATION; MODEL; COMORBIDITIES; VALIDATION; CIRRHOSIS | Carcinoma, Hepatocellular; Cohort Studies; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Risk Factors; alanine aminotransferase; antithrombocytic agent; gamma glutamyltransferase; hydroxymethylglutaryl coenzyme A reductase inhibitor; adult; age; alcohol consumption; Article; asymptomatic infection; CAP B score; chronic hepatitis B; chronic hepatitis C; cohort analysis; coinfection; diabetes mellitus; female; human; liver cell carcinoma; liver transplantation; major clinical study; male; middle aged; mortality rate; predictive model; proportional hazards model; scoring system; smoking; social status; South Korean; chronic hepatitis B; complication; Hepatitis B virus; liver cell carcinoma; liver tumor; risk factor | English | 2022 | 2022-02 | 10.1111/jvh.13631 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Long-term renal safety between patients with chronic hepatitis B receiving tenofovir vs. entecavir therapy: A multicenter study | Renal safety is a critical issue in chronic hepatitis B (CHB) patients receiving long-term entecavir (ETV) or tenofovir disofuroxil fumarate (TDF) therapy. We investigated their effects on estimated glomerular filtration rate (eGFR). Treatment-naive CHB patients receiving ETV or TDF for >= 1 year were recruited. The eGFR was assessed using the Chronic Kidney Disease Epidemiology Collaboration equation. We calculated average annual percent change (AAPC) in eGFR using Joinpoint regression. At the beginning of the observation, the ETV group had more unfavorable conditions than the TDF group: lower eGFR and higher FIB-4 and APRI than the TDF group (all p < .001). After 6 years of antiviral therapy, the mean eGFR in the ETV group (n = 1793) was maintained (96.0 at first year to 95.6 ml/min/1.73 m(2) at sixth year; AAPC -0.09%; p = .322), whereas that in the TDF group (n = 1240) significantly decreased annually (101.9 at first year to 96.9 ml/min/1.73 m(2) at sixth year; AAPC -0.88%; p < .001). Notably, in the TDF group, even patients without diabetes (AAPC -0.80%; p = 0.001) or hypertension (AAPC -0.87%; p = .001) experienced significant decrease in eGFR. Expectably, accompanying diabetes (AAPC -1.59%; p = .011) or hypertension (AAPC -1.00%; p = .002) tended to accelerate eGFR decrease. TDF treatment (odds ratio 1.66, p < .001), along with eGFR<60 ml/min/1.73 m(2), serum albumin<3.5 mg/dl, and hypertension, were independently associated with ongoing renal dysfunction, defined as a negative slope of the mean eGFR change. In conclusion, compared with ETV, long-term TDF treatment induced slow, but progressive renal dysfunction. Although the annual eGFR change by TDF was small, careful monitoring is necessary, especially in patients requiring life-long therapy. | Chon, Young Eun; Park, Soo Young; Kim, Seung Up; Hong, Han Pyo; Lee, Jae Seung; Lee, Hye Won; Kim, Mi Na; Park, Jun Yong; Kim, Do Young; Ahn, Sang Hoon; Kim, Beom Kyung | Cha Univ, Cha Bundang Med Ctr, Dept Internal Med, Seongnam, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, 50-1 Yonsei Ro, Seoul 03722, South Korea; Yonsei Univ Hlth Syst, Severance Hosp, Yonsei Liver Ctr, Seoul, South Korea; Yonsei Univ, Inst Gastroenterol, Coll Med, Seoul, South Korea; Yonsei Univ Wonju Coll Med, Big Data Ctr, Dept Stat, Wonju, South Korea | Kim, Sun/L-4239-2013; Kim, Jung/L-9791-2019; SANG-HOON, AHN/AAV-2600-2020; Ahn, Sang Hoon/AFM-2603-2022; Lee, Hye/D-9081-2016; Hong, Hanpyo/KHU-7470-2024; Kim, Nayoung/J-5387-2012; Kim, Young/T-8521-2019; Park, Jun/H-7127-2019; LEE, JAE SEUNG/KHT-9575-2024; Kim, Yoon/G-6633-2015 | 36089768300; 57191674344; 54933821200; 58817499500; 57204060462; 57200110315; 57202910894; 47861376300; 56119929100; 7401989551; 35302925200 | beomkkim@yuhs.ac; | JOURNAL OF VIRAL HEPATITIS | J VIRAL HEPATITIS | 1352-0504 | 1365-2893 | 29 | 4 | SCIE | GASTROENTEROLOGY & HEPATOLOGY;INFECTIOUS DISEASES;VIROLOGY | 2022 | 2.5 | 75.5 | 0.93 | 2025-06-25 | 8 | 10 | antiviral therapy; chronic hepatitis B; entecavir; renal insufficiency; tenofovir | NUCLEOTIDE ANALOGS; FANCONI SYNDROME; CIRRHOSIS; COHORT | antiviral therapy; chronic hepatitis B; entecavir; renal insufficiency; tenofovir | Antiviral Agents; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Hypertension; Male; Renal Insufficiency, Chronic; Retrospective Studies; Tenofovir; Treatment Outcome; albumin; entecavir; tenofovir; antivirus agent; entecavir; guanine; tenofovir; adult; albumin blood level; antiviral therapy; Article; chronic hepatitis B; clinical outcome; cohort analysis; controlled study; diabetes mellitus; drug safety; estimated glomerular filtration rate; female; Fibrosis-4 Index; follow up; human; hypertension; kidney failure; kidney function; long term care; major clinical study; male; odds ratio; prediction; retrospective study; chronic kidney failure; clinical trial; complication; Hepatitis B virus; hypertension; multicenter study; treatment outcome | English | 2022 | 2022-04 | 10.1111/jvh.13656 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical outcomes of transposed brachial-basilic vein fistula: Tunneling versus elevation | Background: The Kidney Disease Outcome Quality Initiative (KDOQI) suggests a transposed brachial basilic vein fistula (TBBVF) in the patients who have good likelihood of long-term survival. To superficialize the basilic vein, a disconnected basilic vein is anterolaterally transposed inside a subcutaneous tunnel. A simple elevation in situ is an alternative technique. The aim of this study was to compare clinical outcomes of TBBVF according to the type of superficialization. Methods: A total of 42 patients (mean age of 66 years, male: 45%) who underwent a TBBVF from April 2014 to March 2019 at our hospital were retrospectively reviewed. The method of superficialization (tunneling (n = 18) vs elevation (n = 24)) was determined by the surgeon's preference. It was done as a one-stage surgery. There was not any statistically significant difference in demographic or clinical characteristics of patients between the two groups. As early outcomes, postoperative mortality and morbidity were investigated. For clinical outcomes, primary patency, primary-assisted patency, and secondary patency were analyzed for both groups. Results: There was a case of a 30-day mortality in the elevation group. Regarding morbidities, there was a postoperative bleeding in the tunneling group and a steal syndrome in the elevation group. The mean follow-up was 28 months (range, 0-63 months). There was no significant difference in primary patency (64.8% vs 77.5% in 1 year and 54.0% vs 54.1% at 3 year; p = 0.816), primary-assisted patency (88.9% vs 86.5% in 1 year and 88.9 vs 81.4 at 3 year; p = 0.624), or secondary patency (100% vs 86.5% in 1 year and 100% vs 86.5% at 3 year; p = 0.126) between the two groups. Conclusions: Clinical outcomes of TBBVF showed no significant difference between tunneling and elevation groups. Thus, TBBVF can be done with either method. | Kim, Choshin; Yun, Woo-Sung | Yeungnam Univ Hosp, Dept Surg, Div Transplantat & Vasc Surg, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Surg,Div Transplantat & Vasc Surg, Daegu, South Korea | 57211299136; 35070717000 | wsyun@me.com; | JOURNAL OF VASCULAR ACCESS | J VASC ACCESS | 1129-7298 | 1724-6032 | 23 | 6 | SCIE | PERIPHERAL VASCULAR DISEASE | 2022 | 1.9 | 75.7 | 0.34 | 2025-06-25 | 1 | 2 | Basilic vein transposition; superficialization; tunneling; elevation; patency | ARTERIOVENOUS-FISTULA; VASCULAR ACCESS; POLYTETRAFLUOROETHYLENE; HEMODIALYSIS; ARTERY | Basilic vein transposition; elevation; patency; superficialization; tunneling | Aged; Arteriovenous Shunt, Surgical; Brachial Artery; Fistula; Humans; Male; Renal Dialysis; Retrospective Studies; Treatment Outcome; Vascular Patency; aged; arteriovenous fistula; Article; aspiration pneumonia; brachial artery; bypass surgery; clinical outcome; coronary artery disease; diabetes mellitus; dialysis; elevation method; female; hemodialysis; human; hypertension; limb ischemia; male; medical procedures; morbidity; mortality; operation duration; outcome assessment; postoperative hemorrhage; retrospective study; sick sinus syndrome; sinus node; surgical technique; Transposed brachiobasilic arteriovenous fistula; Tunneling method; adverse event; arteriovenous shunt; case report; diagnostic imaging; fistula; procedures; surgery; treatment outcome; vascular patency | English | 2022 | 2022-11 | 10.1177/11297298211018076 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Simple Electric Device to Isolate Nucleic Acids from Whole Blood Optimized for Point of Care Testing of Brain Damage | Background: Detection or monitoring of brain damage is a clinically crucial issue. Nucleic acids in the whole blood can be used as biomarkers for brain injury. Polymerase chain reaction (PCR) which is one of the most commonly used molecular diagnostic assays requires isolated nucleic acids to initiate amplification. Currently used nucleic acid isolation procedures are complicated and require laboratory equipments. Objective In this study, we tried to develop a simple and convenient method to isolate nucleic acids from the whole blood sample using a tiny battery-powered electric device. The quality of the isolated nucleic acids should be suitable for PCR assay without extra preparation. Methods: A plastic device with separation chamber was designed and printed with a 3D printer. Two platinum electrodes were placed on both sides and a battery was used to supply the electricity. To choose the optimal nucleic acid isolation condition, diverse lysis buffers and separation buffers were evaluated, and the duration and voltage of the electricity were tested. Western blot analysis and PCR assay were used to determine the quality of the separated nucleic acids. Results: 2ul of whole blood was applied to the cathode side of the separation chamber containing 78 ul of normal saline. When the electricity at 5 V was applied for 5 min, nucleic acids were separated from segment 1 to 3 of the separation chamber. The concentration of nucleic acids peaked around 7 similar to 8 mm from cathode side. PCR assay using the separation buffer as the template was performed successfully both in conventional and realtime PCR methods. The hemoglobin in the whole blood did not show the inhibitory effect in our separation system and it may be due to structural modification of hemoglobin during electric separation. Conclusion: Our simple electric device can separate nucleic acids from the whole blood sample by applying electricity at 5 V for 5 min. The separation buffer solution taken from the device can be used for PCR assay successfully. | Bae, Mi Jung; Lee, Young Mi; Choi, Ye Seul; Lee, Eunmi; Le, Minh Tan; Nguyen, Thi Hong Duc; Lee, Donghyeon; Cho, Junghwan; Han, Hyung Soo; Park, Nora Jee-Young; Chong, Gun Oh | Kyungpook Natl Univ, Sch Med, Dept Physiol, Daegu 41944, South Korea; Kyungpook Natl Univ, Clin Omics Inst, Daegu 41405, South Korea; Kyungpook Natl Univ, Grad Sch, Dept Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, BK21 Four Program, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Pathol, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ, Dept Obstet & Gynecol, Chilgok Hosp, Daegu 41404, South Korea | Cho, Junghwan/AAK-4752-2020; Le, Tan/ITT-2150-2023 | 56432272400; 57199022012; 57226123444; 57424697000; 57424768200; 57424697100; 57870503500; 57424663500; 7401969388; 57226185359; 23099068000 | hshan@knu.ac.kr; | CURRENT NEUROVASCULAR RESEARCH | CURR NEUROVASC RES | 1567-2026 | 1875-5739 | 19 | 3 | SCIE | CLINICAL NEUROLOGY;NEUROSCIENCES | 2022 | 2.1 | 75.7 | 0 | 2025-06-25 | 0 | 0 | Point of care test; whole blood; nucleic acid; electric device; brain damage; molecular diagnosis | brain damage; electric device; molecular diagnosis; nucleic acid; Point of care test; whole blood | Brain; Brain Injuries; Humans; Nucleic Acid Amplification Techniques; Nucleic Acids; Point-of-Care Testing; buffer; hemoglobin; nucleic acid; plastic; sodium chloride; nucleic acid; Article; blood sampling; brain damage; electric potential; electricity; human; platinum electrode; point of care testing; polymerase chain reaction; real time polymerase chain reaction; three dimensional printing; Western blotting; brain; brain injury; nucleic acid amplification techniques; point of care testing; procedures | English | 2022 | 2022 | 10.2174/1567202619666220903105805 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Evaluation of sex differences in the pharmacokinetics of oral sumatriptan in healthy Korean subjects using population pharmacokinetic modeling | Sumatriptan was introduced in 1983, as the first of the triptans, selective 5-hydroxytryptamine (5-HT1B/1D) receptor agonists, to treat moderate to severe migraine. Migraine predominates in females. Although there have been reports of sex differences in migraine-associated features and pharmacokinetics (PKs) of some triptans, sex differences in the PKs of oral sumatriptan have never been evaluated in Korean. We conducted this study of oral sumatriptan to assess the sex differences in Korean population. Thirty-eight healthy Korean subjects who participated in two separate clinical studies receiving a single oral dose of 50 mg sumatriptan with the same protocols were included in this analysis. A total of 532 sumatriptan concentration observations were used for a population PK modeling. Validation of final population PK model of sumatriptan was performed using bootstrap and visual predictive check. The PK profile of oral sumatriptan was adequately described by a one-compartmental model with combined transit compartment model and a first-order absorption. The covariate analysis showed that the clearance of oral sumatriptan was significantly higher in males than in females (male: 444 L/h, female: 281 L/h). Our results showed that there were sex differences in the clearance of oral sumatriptan. These results encourage further studies to establish the sumatriptan pharmacokinetic-pharmacodynamic model considering sex-related PK differences, which may help to determine optimal dosing regimens for effective treatment of migraine in males and females. Clinical trial registration: CRIS Registration No. KCT0001784. | Ohk, Boram; Seong, Sookjin; Lee, Joomi; Gwon, Miri; Kang, Wooyoul; Lee, Haewon; Yoon, Youngran; Yoo, Heedoo | Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Clin Pharmacol, Daegu, South Korea | 57189367079; 57211130049; 53064009800; 56035800800; 56816263900; 57202973823; 14629744500; 35212801300 | yooheedoo@gmail.com;yry@knu.ac.kr; | BIOPHARMACEUTICS & DRUG DISPOSITION | BIOPHARM DRUG DISPOS | 0142-2782 | 1099-081X | 43 | 1 | SCIE | PHARMACOLOGY & PHARMACY | 2022 | 2.1 | 76.1 | 0.37 | 2025-06-25 | 3 | 3 | migraine; NONMEM; population pharmacokinetics; sex differences; sumatriptan | UNITED-STATES; AMERICAN MIGRAINE; SEVERE HEADACHE; PREVALENCE; VARIABILITY; PLASMA; TOLERABILITY; RIZATRIPTAN; STATISTICS; EXPRESSION | migraine; NONMEM; population pharmacokinetics; sex differences; sumatriptan | Female; Humans; Male; Migraine Disorders; Republic of Korea; Serotonin Receptor Agonists; Sex Characteristics; Sumatriptan; almotriptan; amine oxidase (flavin containing); eletriptan; frovatriptan; indoleacetic acid; monoamine; naratriptan; rizatriptan; serotonin; sumatriptan; sumatriptan succinate; triptan derivative; zolmitriptan; serotonin agonist; sumatriptan; absorption rate constant; adult; area under the curve; Article; bootstrapping; compartment model; data analysis software; drug absorption; drug clearance; drug half life; drug response; drug solubility; electrocardiography; female; headache; human; human experiment; inhibition constant; male; microsome; migraine; normal human; oral clearance; pharmacodynamics; pharmacokinetic parameters; pharmacokinetics; reversed phase ultra performance liquid chromatography; sex difference; single drug dose; tandem mass spectrometry; time to maximum plasma concentration; volume of distribution; migraine; sexual characteristics; South Korea | English | 2022 | 2022-02 | 10.1002/bdd.2307 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | EXPLANATION: Exoplanet and Transient Events Investigation Project | We present a brief description of a joint Russian-Korean project abbreviated as EXPLANATION (EXoPLANet And Transient events InvestigatiON). The project is aimed at a massive photometric, speckle-interferometric, spectral, and radio bolometric search for non-stationary events in the Universe, as well as the study of exoplanets. The core of the project consists of several 0.07-2.5-m optical telescopes, 6-m telescope BTA and a six-hundred-meter radio telescope RATAN-600 of the Special Astrophysical Observatory of RAS (Russia), Moscow State University observatory (Russia), Kourovka Observatory (Russia), Crimean Astrophysical Observatory (Crimea), Korea Astronomy and Space Science Institute (Republic of Korea). We discuss the philosophy of the project and its instrumentation, as well as the first obtained results. In this paper we report the results related to the detection of several types of transient events and the study of exoplanets. | Valyavin, G.; Beskin, G.; Valeev, A.; Galazutdinov, G.; Fabrika, S.; Aitov, V.; Yakovlev, O.; Ivanova, A.; Baluev, R.; Vlasyuk, V.; Han, Inwoo; Karpov, S.; Sasyuk, V.; Perkov, A.; Bondar, S.; Musaev, F.; Emelianov, E.; Fatkhullin, T.; Drabek, S.; Shergin, V.; Lee, Byeong-Cheol; Mitiani, G.; Burlakova, T.; Yushkin, M.; Sendzikas, E.; Gadelshin, D.; Chmyreva, L.; Beskakotov, A.; Dyachenko, V.; Rastegaev, D.; Mitrofanova, A.; Yakunin, I.; Antonyuk, K.; Plokhotnichenko, V.; Gutaev, A.; Lyapsina, N.; Chernenkov, V.; Biryukov, A.; Ivanov, E.; Belinsky, A.; Sokov, E.; Tavrov, A.; Korablev, O.; Park, Myeong-Gu; Stolyarov, V.; Bychkov, V.; Gorda, S.; Popov, A.; Sobolev, A. | Russian Acad Sci, Special Astrophys Observ, Nizhnii Arkhyz 369167, Russia; Kazan Volga Reg Fed Univ, Kazan 420008, Russia; Russian Acad Sci, Crimean Astrophys Observ, Nauchny 298409, Russia; Russian Acad Sci, Space Res Inst, Moscow 117997, Russia; St Petersburg Univ, St Petersburg 199034, Russia; Korea Astron & Space Sci Inst, Daejeon 34055, South Korea; Czech Acad Sci, Cent European Inst Cosmol & Fundamental Phys, Inst Phys, Prague 18221, Czech Republic; Res & Prod Corp Precis Syst & Instruments, Moscow 111024, Russia; Lomonosov Moscow State Univ, Sternberg Astron Inst, Moscow 119234, Russia; Russian Acad Sci, Cent Pulkovo Astron Observ, St Petersburg 196140, Russia; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 41566, South Korea; Univ Cambridge, Cavendish Lab, Cambridge CB3 OHE, England; Ural Fed Univ, Ekaterinburg 620000, Russia | Vlasyuk, Valery/AAL-6731-2021; Shergin, Vladimir/AAC-9828-2022; Rastegaev, Denis/AAR-7816-2020; Stolyarov, Vladislav/C-5656-2017; Драбек, Сергей/AAD-2562-2022; Yakunin, Ilya/J-5730-2018; Gadelshin, Damir/AAM-1943-2021; Beskin, Grigory/AAM-4721-2021; Burlakova, Tatiana/AAM-1942-2021; Baluev, Roman/H-3312-2013; Lyapsina, Nadezhda/AGP-3238-2022; Chernenkov, Vladimir/AAE-1154-2020; Chmyreva, Elizaveta/AAM-4305-2021; Emelianov, Edward/O-1859-2017; Gutaev, Aleksey/ADB-9963-2022; Yushkin, Maxim/AAC-4984-2019; Karpov, Sergey/AAC-8533-2020; Antoniuk, Kirill/AAX-9102-2021; Aitov, Vitaliy/AAL-8090-2021; Yakovlev, Oleg/HOF-2630-2023; Korablev, Oleg/L-5083-2013; Bychkov, Victor/AAM-3026-2021; Ivanova, Anastasiia/AAN-7815-2020; Gorda, Stanislav/AAH-8539-2019; Gutaev, Aleksei/ADB-9963-2022; Valeev, Azamat/G-6634-2018; Beskakotov, Anatoly/S-3262-2018; Dyachenko, Vladimir/T-2186-2018 | 56013549400; 6701631192; 35173619800; 7004144152; 55960862500; 57200092538; 57222568783; 57212340372; 23992093800; 7003589755; 7201559866; 57201302705; 55616974100; 55615991800; 6602096547; 7004166223; 55843637100; 6507462729; 56178558000; 25030670700; 8878262900; 57219801167; 6508218865; 6507635814; 56422438200; 56784405600; 16303015400; 57191619658; 8594973800; 22938989100; 55242156300; 36810723500; 6506713325; 6508123043; 57193378546; 58098714600; 25029933600; 7006918776; 58832004900; 57941684400; 37665885200; 55921187400; 6701419975; 7404490321; 7005641598; 7102540043; 6508371206; 55471152500; 7101981405 | gvalyavin@gmail.com; | ASTROPHYSICAL BULLETIN | ASTROPHYS BULL | 1990-3413 | 1990-3421 | 77 | 4 | SCIE | ASTRONOMY & ASTROPHYSICS | 2022 | 1.2 | 76.1 | 0.64 | 2025-06-25 | 8 | 7 | techniques; photometric; spectroscopic; telescopes; stars; planetary systems; transients | FED ECHELLE SPECTROGRAPH; 2.5-M TELESCOPE; PHOTOMETRIC VARIABILITY; RADIAL-VELOCITY; MAGNETIC-FIELD; 6-M TELESCOPE; ANALYSIS TOOL; SEARCH; CATALOG; BURSTS | stars: planetary systems; techniques: photometric; techniques: spectroscopic; telescopes; transients | English | 2022 | 2022-12 | 10.1134/s1990341322040186 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Molecular Pathology of Gastric Cancer | Gastric cancer (GC) is one of the most common lethal malignant neoplasms worldwide, with limited treatment options for both locally advanced and/or metastatic conditions, resulting in a dismal prognosis. Although the widely used morphological classifications may be helpful for endoscopic or surgical treatment choices, they are still insufficient to guide precise and/or personalized therapy for individual patients. Recent advances in genomic technology and high-throughput analysis may improve the understanding of molecular pathways associated with GC pathogenesis and aid in the classification of GC at the molecular level. Advances in next-generation sequencing have enabled the identification of several genetic alterations through single experiments. Thus, understanding the driver alterations involved in gastric carcinogenesis has become increasingly important because it can aid in the discovery of potential biomarkers and therapeutic targets. In this article, we review the molecular classifications of GC, focusing on The Cancer Genome Atlas (TCGA) classification. We further describe the currently available biomarker-targeted therapies and potential biomarker-guided therapies. This review will help clinicians by providing an inclusive understanding of the molecular pathology of GC and may assist in selecting the best treatment approaches for patients with GC. | Kim, Moonsik; Seo, An Na | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pathol, 807 Hoguk Ro, Daegu, South Korea | 57195918515; 55804153700 | san_0729@naver.com; | JOURNAL OF GASTRIC CANCER | J GASTRIC CANCER | 2093-582X | 2093-5641 | 22 | 4 | SCIE | GASTROENTEROLOGY & HEPATOLOGY;ONCOLOGY | 2022 | 2.5 | 76.1 | 0.54 | 2025-06-25 | 11 | 11 | Gastric cancer; Human genome project; Molecular diagnostic testing; Diagnostic molecular pathology; Biomarker; Molecular targeted therapy | EPSTEIN-BARR-VIRUS; GASTROESOPHAGEAL JUNCTION CANCER; MISMATCH REPAIR-DEFICIENCY; EXPRESSION-BASED CLASSIFICATION; NONPOLYPOSIS COLORECTAL-CANCER; OF-AMERICAN-PATHOLOGISTS; MICROSATELLITE INSTABILITY; GENE AMPLIFICATION; DOUBLE-BLIND; OPEN-LABEL | Biomarker; Diagnostic molecular pathology; Gastric cancer; Human genome project; Molecular diagnostic testing; Molecular targeted therapy | biological marker; brain derived neurotrophic factor receptor; BRCA1 protein; BRCA2 protein; deruxtecan; DNA mismatch repair protein MSH2; epidermal growth factor receptor 2; epidermal growth factor receptor kinase inhibitor; fluorouracil; ipilimumab; mismatch repair protein PMS2; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor; nivolumab; NTRK1; NTRK2; NTRK3; olaparib; paclitaxel; pembrolizumab; peptides and proteins; protein MSH1; protein MSH6; protein MutS; protein p53; protein tyrosine kinase; protein tyrosine kinase A; protein tyrosine kinase inhibitor; trastuzumab; tropomyosin receptor kinase inhibitor; unclassified drug; ACRG classification; Cancer Genome Atlas; cancer staging; cancer therapy; capillary electrophoresis; cell nuclear staining; classification algorithm; digital image analysis; disease free survival; endoscopic surgery; Epstein Barr virus; fluorescence in situ hybridization; fluorescent polymerase chain reaction; gene amplification; gene expression; gene fusion; high throughput sequencing; human; human genome project; image analysis; immunohistochemistry; in situ hybridization; microsatellite instability; mismatch repair; molecular pathology; molecularly targeted therapy; multiplex polymerase chain reaction; pathogenesis; Review; short tandem repeat; Singapore-Duke classification; stomach cancer; TCGA molecular classification; tumor mutational burden; whole genome sequencing | English | 2022 | 2022-10 | 10.5230/jgc.2022.22.e35 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Glycine induces enhancement of bactericidal activity of neutrophils | Severe bacterial infections are frequently accompanied by depressed neutrophil functions. Thus, agents that increase the microbicidal activity of neutrophils could add to a direct antimicrobial therapy. Lysophosphatidylcholine augments neutrophil bactericidal activity via the glycine (Gly)/glycine receptor (GlyR) alpha 2/TRPM2/p38 mitogen-activated protein kinase (MAPK) pathway. However, the direct effect of glycine on neutrophil bactericidal activity was not reported. In this study, the effect of glycine on neutrophil bactericidal activity was examined. Glycine augmented bactericidal activity of human neutrophils (EC50 = 238 mu M) in a strychnine (a GlyR antagonist)-sensitive manner. Glycine augmented bacterial clearance in mice, which was also blocked by strychnine (0.4 mg/kg, s.c.). Glycine enhanced NADPH oxidase-mediated reactive oxygen species ( ROS) production and TRPM2-mediated [Ca2+](i) increase in neutrophils that had taken up E. coli. Glycine augmented Lucifer yellow uptake (fluid-phase pinocytosis) and azurophil granule-phagosome fusion in neutrophils that had taken up E. coli in an SB203580 (a p38 MAPK inhibitor)-sensitive manner. These findings indicate that glycine augments neutrophil microbicidal activity by enhancing azurophil granule-phagosome fusion via the GlyR alpha 2/ROS/calcium/p38 MAPK pathway. We suggest that glycine could be a useful agent for increasing neutrophil bacterial clearance. | Kang, Shin-Hae; Ham, Hwa-Yong; Hong, Chang-Won; Song, Dong-Keun | Hallym Univ, Dept Pharmacol, Coll Med, Chuncheon 24252, Peoples R China; Kyungpook Natl Univ, Sch Med, Dept Physiol, Daegu 41944, South Korea | 57218255777; 36109808800; 55567018400; 7402443736 | cwhong@knu.ac.kr;dksong@hallym.ac.kr; | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | KOREAN J PHYSIOL PHA | 1226-4512 | 2093-3827 | 26 | 4 | SCIE | PHARMACOLOGY & PHARMACY;PHYSIOLOGY | 2022 | 2 | 76.6 | 0.32 | 2025-06-25 | 3 | 4 | Calcium; Glycine; Neutrophil; p38 MAPK; Reactive oxygen species | RESPIRATORY BURST; PHAGOSOME FUSION; NADPH OXIDASE; AMINO-ACIDS; IN-VITRO; RECEPTOR; DYSFUNCTION; ACTIVATION; CHANNELS; ELASTASE | Calcium; Glycine; Neutrophil; p38 MAPK; Reactive oxygen species | adezmapimod; glycine; glycine receptor; mitogen activated protein kinase p38; reactive oxygen metabolite; reduced nicotinamide adenine dinucleotide phosphate oxidase; strychnine; transient receptor potential channel M2; animal cell; Article; bacterial clearance; bactericidal activity; cell fractionation; cellular distribution; controlled study; EC50; Escherichia coli; human; human cell; male; microbicidal activity; mouse; neutrophil; nonhuman; phagosome; pinocytosis; signal transduction | English | 2022 | 2022-07 | 10.4196/kjpp.2022.26.4.229 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Ameliorative effect of Abeliophyllum distichum Nakai on benign prostatic hyperplasia in vitro and in vivo | BACKGROUND/OBJECTIVES: Benign prostatic hyperplasia (BPH) is the most common prostate disease and one of the most common chronic diseases caused by aging in men. On the other hand, there has been no research on BPH using Abeliophyllum distichum Nakai (A. distichum). Therefore, this study investigated the effects ofA. distichum on BPH. MATERIALS/METHODS: A. distichum leaves were extracted with distilled water, 70% ethanol, and 95% hexane as solvents. Subsequently, the inhibitory effects of each A. distichum extract on androgen receptor (AR) signaling were evaluated in vitro. The testosterone-induced BPH model was then used to confirm the efficacy ofA. distichum leaves in 70% ethanol extract (ADLE). RESULTS: ADLE had the strongest inhibitory effect on AR signaling. A comparison of the activity of ADLE by harvest time showed that the leaves ofA. distichum harvested in autumn had a superior inhibitory effect on AR signaling to those harvested at other times. In the BPH rat model, the administration of ADLE reduced the prostate size and prostate epithelial cell thickness significantly and inhibited AR signaling. Subsequently, the administration of ADLE also reduced the expression of growth factors, thereby inactivating the PI3K/AKT pathway. CONCLUSIONS: An analysis of the efficacy of ADLE to relieve BPH showed that the ethanol extract grown in autumn exhibited the highest inhibitory ability of the androgen-signaling related factors in vitro. ADLE also inhibited the expression of growth factors by inhibiting the expression of the androgen-signaling related factors in vivo. Overall, ADLE is proposed as a functional food that is effective in preventing BPH. | Choi, Young-Jin; Fan, Meiqi; Tang, Yujiao; Moon, Sangho; Lee, Seung-Hyun; Lee, Bokyung; Bae, Sung Mun; Lee, Sang Moo; Kim, Eun-Kyung | Dong A Univ, Dept Food Sci & Nutr, 3 Nakdong Daero 550Beon Gil, Busan 49315, South Korea; Dong A Univ, Brain Busan 21 Plus Program, Ctr Silver Targeted Biomat, Busan 49315, South Korea; Konkuk Univ, Coll Biomed & Hlth Sci, Div Food Biosci, Chungju 27478, South Korea; Changchun Univ Sci & Technol, Sch Biosci & Food Engn, Changchun 130600, Peoples R China; Konkuk Univ, Sch Med, Dept Microbiol, Chongju 27478, South Korea; Gyeongnam Agr Res & Extens Serv, Jinju 52733, South Korea; Kyungpook Natl Univ, Dept Anim Sci, Sangju 37224, South Korea | ; 唐, 玉娇/KBQ-5971-2024; Fan, Meiqi/JNZ-5367-2023; fan, meiqi/JNZ-5367-2023 | 57195621796; 57202091337; 56582986300; 8333204200; 57225889386; 55919205100; 39160991700; 37059282800; 57201655352 | ekkimkr@dau.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 16 | 4 | SCIE | NUTRITION & DIETETICS | 2022 | 2.4 | 76.7 | 0.29 | 2025-06-25 | 2 | 3 | Androgen receptor; dihydrotestosterone; prostatic hyperplasia; cell proliferation | ANDROGEN RECEPTOR; 5-ALPHA-REDUCTASE INHIBITORS; SAW PALMETTO; DIHYDROTESTOSTERONE; TESTOSTERONE; DYSFUNCTION; ACTIVATION; THERAPY; EXTRACT; TRACT | Androgen receptor; cell proliferation; dihydrotestosterone; prostatic hyperplasia | English | 2022 | 2022-08 | 10.4162/nrp.2022.16.4.419 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Development and application of the sodium index to estimate and assess sodium intake for Korean adults | BACKGROUND/OBJECTIVES: The purpose of this study was to develop a sodium index, which is a tool for estimating and assessing sodium intake easily and quickly, to assist in the prevention of various diseases induced by excess sodium intake in Korean adults. SUBJECTS/METHODS: The 24-h urine collection and dietary behavior surveys were performed on 640 healthy people in 4 regions of South Korea, and an equation for the estimation of 24-h sodium intake was developed. The validity and reliability of the equation were verified with 200 adults. The sodium index was developed by converting the estimated sodium intake using the equation. Finally, the sodium intake status of 1,600 adults was assessed using the sodium index. RESULTS: The equation included sex, age, body mass index, eating habit and dietary behaviors related to sodium intake. In validity test of the equation, the mean bias between sodium intake using 24-h urine analysis and using the equation from the Bland-Altman plots was -1.5 mg/day. The sensitivity and specificity of the equation for estimation of sodium intake were 80.5% and 64.4%, respectively. In the reliability test of the equation, there was no significant difference between the first and second sodium intakes calculated using the equations, and Spearman's correlation coefficient between the 2 sodium intakes was 0.98. Sodium intake can be assessed as 'very moderate' for 75-100 on the sodium index, 'moderate' for 100-150, 'careful' for less than 75 or 150-200, and 'severe' for 250 or more. When sodium intake was assessed using the sodium index in 1,600 subjects, 54.3% and 24.3% of the subjects were assessed to be in the 'careful' and 'severe' categories, respectively. CONCLUSIONS: Using a simple questionnaire, the sodium index can be used to monitor and assess sodium intake status, assisting in nutrition education and counseling in a large population. | Lee, Yeon-Kyung; Hyun, Taisun; Ro, Heekyong; Heo, Young-Ran; Choi, Mi-Kyeong | Kyungpook Natl Univ, Dept Food Sci & Nutr, Daegu 41566, South Korea; Chungbuk Natl Univ, Dept Food & Nutr, Cheongju 28644, South Korea; Dongshin Univ, Dept Food & Nutr, Naju 58245, South Korea; Chonnam Natl Univ, Res Inst Human Ecol, Div Food & Nutr, Gwangju 61186, South Korea; Kongju Natl Univ, Dept Food & Nutr, 54 Daehak Ro, Yesan 32439, South Korea | Lee, Yeon-Kyung/AAA-1916-2020 | 16301462200; 36729177900; 24167503200; 7004298545; 22833250600 | mkchoi67@kongju.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 16 | 3 | SCIE | NUTRITION & DIETETICS | 2022 | 2.4 | 76.7 | 0.19 | 2025-06-25 | 0 | 2 | Sodium index; reliability and validity; diet; urine | 24-H URINARY SODIUM; SALT INTAKE; POTASSIUM EXCRETION; HEALTH; SPOT | diet; reliability and validity; Sodium index; urine | English | 2022 | 2022-06 | 10.4162/nrp.2022.16.3.366 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Dietary Reference Intakes of sodium for Koreans: focusing on a new DRI component for chronic disease risk reduction | Sodium is a physiologically essential nutrient, but excessive intake is linked to the increased risk of various chronic diseases, particularly cardiovascular. It is, therefore, necessary to accomplish an evidence-based approach and establish the Korean Dietary Reference Intakes (KDRIs) index, to identify both the nutritional adequacy and health effects of sodium. This review presents the rationale for and the process of revising the KDRIs for sodium and, more importantly, establishing the sodium Chronic Disease Risk Reduction Intake (CDRR) level, which is a new specific set of values for chronic disease risk reduction. To establish the 2020 KDRIs for dietary sodium, the committee conducted a systematic literature review of the intake???response relationships between the selected indicators for sodium levels and human chronic diseases. In this review, 43 studies published from January 2014 to December 2018, using databases of PubMed and Web of Science, were finally included for evaluating the risk of bias and strength of evidence (SoE). We determined that SoE of the relationship between dietary sodium and cardiovascular diseases, cerebrovascular disease, and hypertension, was moderate to strong. However, due to insufficient scientific evidence, we were unable to establish the estimated average requirement and the recommended nutrient intake for dietary sodium. Therefore, the adequate intake of sodium for adults was established to be 1,500 mg/day, whereas the CDRR for dietary sodium was established at 2,300 mg/day for adults. Intake goal for dietary sodium established in the 2015 KDRIs instead of the tolerable upper intake level was not presented in the 2020 KDRIs. For the next revision of the KDRIs, there is a requirement to pursue further studies on nutritional adequacy and toxicity of dietary sodium, and their associations with chronic disease endpoint in the Korean population. | Kim, Hyun Ja; Lee, Yeon-Kyung; Koo, Hoseok; Shin, Min-Jeong | Gangneung Wonju Natl Univ, Dept Food & Nutr, Kangnung 25457, South Korea; Kyungpook Natl Univ, Dept Food Sci & Nutr, Daegu 41566, South Korea; Inje Univ, Seoul Paik Hosp, Dept Internal Med, Seoul 04551, South Korea; Korea Univ, Coll Hlth Sci, Sch Biosyst & Biomed Sci, 145 Anam Ro, Seoul 02841, South Korea | koo, hoseok/Y-3228-2019; Kim, Jinkwon/AAR-6729-2021; Lee, Yeon-Kyung/AAA-1916-2020 | 57206212422; 16301462200; 56888361500; 7401536640 | mjshin@korea.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 16 | SCIE | NUTRITION & DIETETICS | 2022 | 2.4 | 76.7 | 0.16 | 2025-06-25 | 4 | 4 | Sodium; Dietary Reference Intake; South Korea | NUTRITION EXAMINATION SURVEY; HIGH BLOOD-PRESSURE; TO-POTASSIUM RATIO; CARDIOVASCULAR-DISEASE; NATIONAL-HEALTH; SERUM-LIPIDS; WEIGHT-LOSS; SALT INTAKE; EXCRETION; ASSOCIATION | Dietary Reference Intake; Sodium; South Korea | English | 2022 | 2022-05 | 10.4162/nrp.2022.16.s1.s70 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Eating away from home is associated with overweight and obesity among Ugandan adults: the 2014 Uganda non-communicable disease risk factor survey | BACKGROUND/OBJECTIVES: We investigated the associations between eating away from home (EAFH) and overweight and obesity among Ugandan adults using the 2014 Uganda non-communicable disease risk factor survey. SUBJECTS/METHODS: In total, 3,025 participants aged 18???69 years were included in the analysis. The frequency of EAFH was assessed by asking participants the number of meals eaten per week that were not prepared at a home. EAFH frequency was categorized as; less than once/week, 1-2 times/week, or >-3 times/week. Logistic regression was used to evaluate the associations between overweight, obesity, and EAFH. We also tested whether sex and age modified these associations. RESULTS: Participants that ate away from home >-3 times/week were 2.13 times more likely to be obese than those that ate away from home less than once/week (odds ratio [OR], 2.13; 95% confidence interval [CI], 1.28???3.54). However, when the analysis was stratified by sex, women that ate away from home >-3 times/week were 42% less likely to be overweight than those that ate away from home less than once/week (OR, 0.58; 95% CI, 0.36???0.94). Men that ate away from home >-3 times a week were 3.89 times and 2.23 times more likely to be obese and overweight, respectively, than those that ate away from home less than once/week (obesity: OR, 3.89; 95% CI, 1.50???10.09; overweight: OR, 2.23; 95% CI, 1.42???3.51). Age-stratified analysis showed that among participants aged 31???50 years, those that ate away from home >-3 times a week were 3.53 times more likely to be obese than those that ate away from home less than once/week (OR, 3.53; 95% CI, 1.69???7.37). CONCLUSIONS: Frequent EAFH was positively associated with overweight and obesity among men, and obesity among young/middle-aged adults, but negatively associated with overweight in women. Nutritional interventions for obesity reduction in Uganda should include strategies aimed at reducing the frequency of eating meals prepared away from home, and specifically target men and young/middle-aged adults. | Kityo, Anthony; Park, Pil-Sook | Kyungpook Natl Univ, Dept Food Sci & Nutr, 80 Daehak Ro, Daegu 41566, South Korea | ; Kityo, Anthony/GSD-9119-2022 | 57375683100; 55909315600 | pspark@knu.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 16 | 3 | SCIE | NUTRITION & DIETETICS | 2022 | 2.4 | 76.7 | 0.39 | 2025-06-25 | 3 | 4 | Obesity; overweight; eating; adults | OUT-OF-HOME; LOW-INCOME AREAS; FOOD-CONSUMPTION; NUTRITION TRANSITION; DIETARY-INTAKE; STREET FOODS; YOUNG-ADULTS | adults; eating; Obesity; overweight | English | 2022 | 2022-06 | 10.4162/nrp.2022.16.3.379 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Sodium content changes between 2015 and 2019 in restaurant menu items selected for sodium reduction in Daegu | BACKGROUND/OBJECTIVES: South Korea has been conducting the Sodium Reduction Restaurant Project since 2015 to reduce sodium contents in restaurant menus. The purpose of this study was to analyze changes in the sodium content of menus as determined by the Daegu Sodium Reduction Restaurant Project between 2015 and 2019. MATERIALS/METHODS: Intervention was aimed at reducing the sodium contents of over 10% of menu items in participating restaurants. On-site inspections and evaluations were conducted using a checklist, and reductions in sodium contents were determined by analyzing the salinities and sodium contents of menus after intervention. RESULTS: Post-intervention salinities and sodium contents were significantly lower than baseline values in 2016 (P < 0.001), 2017 (P < 0.001), 2018 (P < 0.001), and 2019 (P < 0.001). However, sodium contents and salinities differences before and after intervention were not significant in 2015. Sodium contents of more than 20% of menu items offered by restaurants that participated in the Sodium Reduction Restaurant Project for 2 yrs starting in 2016 declined by 28.9%. On the other hand, the sodium reduction rate achieved by restaurants that participated for 4 yrs from 2015 reached 55.4%. The percentage of restaurants that participated in the project increased annually, though some failed to be designated as Sodium Reduction Restaurants because they did not meet sodium reduction rate requirements. CONCLUSIONS: Positive correlations were found between duration of participation in the project and sodium reduction and designation rates. Sustainable long-term support at the national level is required to expand the project to other regions. | Ma, Jian; Lee, Yeon-Kyung | Kyungpook Natl Univ, Dept Food Sci & Nutr, 80 Daehak Ro, Daegu 41566, South Korea | Lee, Yeon-Kyung/AAA-1916-2020; Ma, Jian/HLW-5119-2023 | 57218175449; 16301462200 | yklee@knu.ac.kr; | NUTRITION RESEARCH AND PRACTICE | NUTR RES PRACT | 1976-1457 | 2005-6168 | 16 | 4 | SCIE | NUTRITION & DIETETICS | 2022 | 2.4 | 76.7 | 0 | 2025-06-25 | 0 | 0 | Sodium; salinity; restaurants | FOOD; RISK | restaurants; salinity; Sodium | English | 2022 | 2022-08 | 10.4162/nrp.2022.16.4.537 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Atopic asthma as a potentially significant but unrecognized risk factor for Kawasaki disease in children | Objectives Childhood asthma is known to be associated with risks of both respiratory and non-respiratory infections. Little is known about the relationship between asthma and the risk of Kawasaki disease (KD). We assessed associations of asthma status and asthma phenotype (e.g. atopic asthma) with KD. Methods We performed a population-based retrospective case-control study, using KD cases between January 1, 1979, and December 31, 2016, and two matched controls per case. KD cases were defined by the American Heart Association diagnostic criteria. Asthma status prior to KD (or control) index dates was ascertained by the two asthma criteria, Predetermined Asthma Criteria (PAC) and Asthma Predictive Index (API, a surrogate phenotype of atopic asthma). We assessed whether 4 phenotypes (both PAC + and API+; PAC + only; API + only, and non-asthmatics) were associated with KD. Results There were 124 KD cases during the study period. The group having both PAC + and API + was significantly associated with the increased odds of KD, compared to non-asthmatics (odds ratio [OR] 4.3; 95% CI: 1.3 - 14.3). While asthma defined by PAC was not associated with KD, asthma defined by PAC positive with eosinophilia (>= 4%) was significantly associated with the increased odds of KD (OR: 6.7; 95% CI: 1.6 - 28.6) compared to non-asthmatics. Asthma status defined by API was associated with KD (OR = 4.7; 95% CI: 1.4-15.1). Conclusions Atopic asthma may be associated with increased odds of KD. Further prospective studies are needed to determine biological mechanisms underlying the association between atopic asthma and increased odds of KD. | Choi, Bong Seok; Taslakian, Editt Nikoyan; Wi, Chung-Il; Shin, Youn Ho; Seol, Hee Yun; Ryu, Euijung; Boyce, Thomas G.; Johnson, Jonathan N.; King, Katherine S.; Kwon, Jung Hyun; Juhn, Young J. | Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Mayo Clin, Precis Populat Med Lab, Rochester, MN 55905 USA; Univ Washington, Med Ctr, Div Plast Surg, Dept Surg, Seattle, WA 98195 USA; CHA Univ, CHA Gangnam Med Ctr, Dept Pediat, Sch Med, Seoul, South Korea; Pusan Natl Univ, Dept Internal Med, Yangsan Hosp, Yangsan, South Korea; Mayo Clin, Div Biomed Stat & Informat, Rochester, MN 55905 USA; Levine Childrens Hosp, Dept Pediat, Charlotte, NC USA; Mayo Clin, Dept Pediat & Adolescent Med, Rochester, MN 55905 USA; Korea Univ, Coll Med, Dept Pediat, Seoul, South Korea | ; Patthipati, Venkata Suresh/AAT-8233-2021; Taslakian, Editt/AFL-8241-2022 | 56547873100; 57214152346; 56182827700; 59113983600; 57208402180; 24077625100; 7005349443; 55343452300; 57007705400; 57191477869; 6507775791 | Juhn.young@mayo.edu; | JOURNAL OF ASTHMA | J ASTHMA | 0277-0903 | 1532-4303 | 59 | 9 | SCIE | ALLERGY;RESPIRATORY SYSTEM | 2022 | 1.9 | 76.8 | 0 | 2025-06-25 | 0 | 0 | Epidemiology; pediatrics; phenotypes | LONG-TERM MANAGEMENT; HEALTH-PROFESSIONALS; HERPES-ZOSTER; UNITED-STATES; ASSOCIATION; DIAGNOSIS; EPIDEMIOLOGY; EOSINOPHILIA; ROCHESTER; YOUNG | Epidemiology; pediatrics; phenotypes | Asthma; Case-Control Studies; Humans; Mucocutaneous Lymph Node Syndrome; Retrospective Studies; Risk Factors; allergic asthma; Article; asthmatic state; case control study; child; controlled study; disease association; eosinophilia; female; human; major clinical study; male; medical society; mucocutaneous lymph node syndrome; respiratory tract disease assessment; retrospective study; risk factor; asthma; complication; mucocutaneous lymph node syndrome | English | 2022 | 2022-09-02 | 10.1080/02770903.2021.1963765 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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