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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Inhibitory Activities of GDX-365 on HMGB1-mediated Septic Responses | GDX-365, is the main fraction of black ginseng comprising protopanaxatriol-type rare ginsenosides (ginsenosides Rg3, Rk1, and Rg5). High mobility group box 1 (HMGB1) is known as a late mediator of sepsis. There are no reported research on the antiseptic properties of GDX-365. The suppression of HMGB1 release and restoration of vascular barrier integrity have emerged as promising therapeutic approaches for sepsis management. In this study, we looked at how GDX-365 affected the survival rate and HMGB1-mediated septic responses in a mouse sepsis model. The mice were given GDX-365 following the HMGB1 challenge. Using sepsis mouse model by cecal ligation and puncture (CLP) and human umbilical vein endothelial cells (HUVECs), measurements of permeability, and septic animal mortality, the antiseptic activity of GDX-365 was evaluated under septic conditions. We discovered that GDX-365 greatly decreased the release of HMGB1 from CLP-induced release of HMGB1 in mice and Lipopolysaccharide-activated HUVECs. Inhibiting hyper-permeability in the animals and restoring HMGB1-mediated vascular disruption were other effects of GDX-365. Additionally, GDX-365 therapy decreased in vivo sepsis-related mortality. Our findings imply that GDX-365 is effective in the treatment of sepsis since it lowers HMGB1 release and septic mortality in vivo. | Baek, Dong-Hyuk; Kim, Go Oun; Choi, Hui-Ji; Yun, Mi-Young; Park, Dong Ho; Song, Gyu Yong; Bae, Jong-Sup | Chungnam Natl Univ, Coll Pharm, Daejeon 34134, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Coll Pharm, Daegu 41566, South Korea; Kwangju Womens Univ, Dept Beauty Sci, Gwangju 62396, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Ophthalmol, Daegu 41944, South Korea | Bae, Jong-Sup/AAU-9724-2020 | 58352627600; 57896809800; 57220585937; 35886891300; 36676632900; 7402253074; 16021543200 | gysong@cnu.ac.kr;baejs@knu.ac.kr; | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | BIOTECHNOL BIOPROC E | 1226-8372 | 1976-3816 | 28 | 4 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0.76 | 2025-06-25 | 6 | 6 | GDX-365; permeability; HMGB1; sepsis | NF-KAPPA-B; HMGB1; GINSENOSIDES; SEPSIS; RG5 | GDX-365; HMGB1; permeability; sepsis | Endothelial cells; antiinfective agent; gdx 365; ginsenoside; high mobility group B1 protein; interleukin 6; isoflurane; lipopolysaccharide; tiletamine plus zolazepam; tumor necrosis factor; unclassified drug; xylazine; GDX-365; Ginsenosides; High mobility group box 1; High-mobility groups; Human umbilical vein endothelial cells; In-vivo; Inhibitory activity; Permeability; Property; Sepsis; animal cell; animal experiment; animal model; animal tissue; antimicrobial activity; Article; blood vessel permeability; cecal ligation and puncture-induced sepsis; controlled study; high performance liquid chromatography; human; human cell; in vivo study; male; mortality; mouse; nonhuman; survival rate; tissue injury; umbilical vein endothelial cell; Mammals | English | 2023 | 2023-08 | 10.1007/s12257-023-0043-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Microbacterium elymi sp. nov., Isolated from the Rhizospheric Soil of Elymus tsukushiensis, a Plant Native to the Dokdo Islands, Republic of Korea | Microbacterium elymi KUDC0405T was isolated from the rhizosphere of Elymus tsukushiensis from the Dokdo Islands. The KUDC0405T strain was Gram-stain-positive, non-spore forming, non-motile, and facultatively anaerobic bacteria. Strain KUDC0405Twas a rod-shaped bacterium with size dimensions of 0.3-0.4 x 0.7-0.8 mu m. Based on 16S rRNA gene sequences, KUDC0405T was most closely related to Microbacterium bovistercoris NEAU-LLET (97.8%) and Microbacterium pseudoresistens CC-5209T (97.6%). The dDDH (digital DNA-DNA hybridization) values between KUDC0405T and M. bovistercoris NEAU-LLET and M. pseudoresistens CC-5209T were below 17.3% and 17.5%, respectively. The ANI (average nucleotide identity) values among strains KUDC0405T, M. bovistercoris NEAU-LLET, and M. pseudoresistens CC-5209T were 86.6% and 80.7%, respectively. The AAI (average amino acid identity) values were 64.66% and 64.97%, respectively, between KUDC0405T and its closest related type strains. The genome contained 3,596 CDCs, three rRNAs, 46 tRNAs, and three non-coding RNAs (ncRNAs). The genomic DNA GC content was 70.4%. The polar lipids included diphosphatydilglycerol, glycolipid, phosphatydilglycerol, and unknown phospholipid, and the major fatty acids were anteiso-C17:0 and iso-C16:0. Strain KUDC0405T contained MK-12 as the major menaquinone. Based on genotypic, phylogenetic, and phenotypic properties, strain KUDC0405T should be considered a novel species within the genus Microbacterium, for which we propose the name M. elymi sp. nov., and the type strain as KUDC0405T (=KCTC 49411T, =CGMCC1.18472T). | Hwang, Ye-Ji; Lee, Soo-Yeong; Son, Jin-Soo; Youn, Jin-suk; Lee, Woong; Shin, Jae-Ho; Lee, Mi-Hwa; Ghim, Sa-Youl | Nakdonggang Natl Inst Biol Resources, Microbiol Res Dept, Sangju 37242, South Korea; KRIBB, Infect Dis Res Ctr, Mol Phytobacteriol Lab, Daejeon 34141, South Korea; Kyungpook Natl Univ, Res Inst Dok Do & Ulleung Do Isl, Sch Life Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Appl Biosci, Daegu 41566, South Korea | 55279513600; 57205313627; 55311904400; 57210840807; 57193846823; 57224125922; 55535507900; 7003577307 | blume96@nnibr.re.kr;ghimsa@knu.ac.kr; | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | J MICROBIOL BIOTECHN | 1017-7825 | 1738-8872 | 33 | 2 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0.17 | 2025-06-25 | 1 | 1 | Microbacterium; novel bacterium; Elymus tsukushiensis; Dokdo Islands | WEB SERVER; TREES; BASE | Dokdo Islands; Elymus tsukushiensis; Microbacterium; novel bacterium | Bacterial Typing Techniques; DNA, Bacterial; Elymus; Fatty Acids; Microbacterium; Phylogeny; Republic of Korea; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil Microbiology; amino acid; bacterial RNA; cytosine; diphosphatydilglycerol; fatty acid; genomic DNA; glycerol; glycolipid; guanine; menaquinone; nucleotide; phosphatydilglycerol; phospholipid; ribosome RNA; RNA 16S; transfer RNA; unclassified drug; untranslated RNA; bacterial DNA; fatty acid; RNA 16S; 16S rRNA gene; Article; bacterial genome; bacterial strain; bacterium isolation; controlled study; DNA DNA hybridization; Elymus; Elymus tsukushiensis KUDC0405T; gene sequence; genotype; Gram positive bacterium; island (geological); Microbacterium; Microbacterium bovistercoris NEAU-LLET; Microbacterium elymi; Microbacterium pseudoresistens CC-5209T; native species; nonhuman; phenotype; phylogeny; rhizosphere; rhizosphere bacterium; soil microflora; South Korea; bacterium identification; chemistry; DNA sequence; genetics; Microbacterium; microbiology; South Korea | English | 2023 | 2023-02 | 10.4014/jmb.2211.11024 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Multi-bioinspired Sprayable Nanotherapeutics for Tumor-Specific Focal Cancer Therapy | Chemotherapy is commonly used to treat cancer. However, insufficient retention at the target site and systemic toxicity remains critical challenges. Chitosan has attracted considerable attention as a carrier backbone for delivering therapeutic cargos because of its biocompatibility and mucoadhesive property. However, pH and concentration-dependent solubility of chitosan has been restricted further applications to clinical settings. Inspired by marine mussels and crustaceans, in this study, we present chitosan-based nanoparticles containing catechol-Fe3+ complexes (Cat-CS NPs) as a tumor-activatable delivery system to achieve highly efficient locoregional treatment of cancer via a simple spray process while minimizing adverse effects towards surrounding normal tissues. Cat-CS NPs were fabricated through electrospraying and exhibited superior adhesiveness on substrates in aqueous conditions in a surface-independent manner. The pH-responsive stoichiometry of catechol-Fe3+ coordination in doxorubicin (DOX)-loaded Cat-CS NPs (Cat-CS@DOX NPs) enabled a triggered release of DOX in response to acidic conditions around tumor tissues. The sprayed Cat-CS@DOX NPs significantly inhibited cancer cell growth in vitro while exhibiting good biocompatibility towards normal cells. Taken together, Cat-CS NP-based sprayable nanotherapeutics can be used as a locoregional delivery system, especially in adjuvant cancer therapy. | Jeon, Yu Ri; Jo, Yun Kee | Kyungpook Natl Univ, Sch Convergence, Dept Biomed Convergence Sci & Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Daegu 41944, South Korea | 58665570000; 56123757800 | ykjo@knu.ac.kr; | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | BIOTECHNOL BIOPROC E | 1226-8372 | 1976-3816 | 28 | 5 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0.3 | 2025-06-25 | 2 | 2 | catechol-chitosan conjugate; adhesive nanoparticles; surgical spray; metal coordination; adjuvant cancer therapy | CHITOSAN HYDROGELS; DRUG-DELIVERY; CATECHOL; NANOPARTICLES; RELEASE; POLYMER | adhesive nanoparticles; adjuvant cancer therapy; catechol-chitosan conjugate; metal coordination; surgical spray | Biocompatibility; Cell proliferation; Chemotherapy; Chitosan; Diseases; Histology; Iron compounds; Metal nanoparticles; Oncology; Phenols; Tumors; 1 (3 dimethylaminopropyl) 3 ethylcarbodiimide; adhesive agent; adjuvant; chitosan; dihydrocaffeic acid; doxorubicin; ferric ion; nanoparticle; Adhesive nanoparticle; Adjuvant cancer therapy; Cancer therapy; Catechol-chitosan conjugate; Delivery systems; Doxorubicin; Fe 3+; Metal coordination; Sprayable; Surgical spray; adhesion; aerosol; animal experiment; animal tissue; antineoplastic activity; Article; biocompatibility; cancer adjuvant therapy; cancer growth; cancer therapy; controlled study; Crustacea; flow cytometry; human; hydrodynamics; in vitro study; molecular weight; mussel; nonhuman; nuclear magnetic resonance; photon correlation spectroscopy; post hoc analysis; stoichiometry; ultraviolet visible spectroscopy; Adhesives | English | 2023 | 2023-10 | 10.1007/s12257-023-0224-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Physicochemical and Functional Properties of Yeast-Fermented Cabbage | Microbial fermentation is often used to improve the functionality of plant-based food materials. Herein, we investigated changes in the physicochemical and functional properties of cabbage during yeast fermentation to develop new products using fermented cabbage. Among the 8 types of food-grade yeast, both Saccharomyces cerevisiae and Saccharomyces boulardii fermented 10% cabbage powder solution (w/w) the most effectively, leaving no soluble sugars after 12 h of fermentation. In addition, the yeast fermentation of cabbage resulted in functionally positive outcomes in terms of sulforaphane content, antioxidant properties, and anti-inflammatory activity. Specifically, the yeast-fermented cabbages contained about 500% more sulforaphane. The soluble fraction (5 mu g/ml) of yeast-fermented cabbage had no cytotoxicity in murine RAW 264.7 cells, and the radical -scavenging capacity was equivalent to 1 mu g/ml of ascorbic acid. Moreover, cabbage fermented with S. boulardii significantly suppressed both lipopolysaccharides (LPS)-induced nitric oxide production and LPS-induced reactive oxygen species production in RAW 264.7 cells, suggesting a potential anti-inflammatory effect. These results support the idea that yeast fermentation is promising for developing functionally improved cabbage products. | Chun, Ahhyeon; Paik, So Jeong; Park, Jongbeom; Kim, Ryeongeun; Park, Sujeong; Jung, Sung Keun; Kim, Soo Rin | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Tailored Food Technol, Daegu 41566, South Korea | Jung, SUNG KEUN/AGR-2623-2022; Kim, Soo Rin/X-2192-2019 | 58673232400; 58161897900; 57223133187; 57900860000; 57218916250; 35310491400; 36659584200 | skjung04@knu.ac.kr;soorinkim@knu.ac.kr; | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | J MICROBIOL BIOTECHN | 1017-7825 | 1738-8872 | 33 | 10 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0.69 | 2025-06-25 | 4 | 4 | Anti-inflammatory activity; Saccharomyces cerevisiae; sulforaphane | INFLAMMATION; PROBIOTICS; BACTERIA; FOODS | Anti-inflammatory activity; Saccharomyces cerevisiae; sulforaphane | Animals; Anti-Inflammatory Agents; Brassica; Fermentation; Lipopolysaccharides; Mice; Saccharomyces cerevisiae; ascorbic acid; carbohydrate; lipopolysaccharide; nitric oxide; reactive oxygen metabolite; sulforaphane; antiinflammatory agent; antiinflammatory activity; antioxidant activity; Article; cabbage; chemical composition; cytotoxicity; fermentation; fermented product; nonhuman; physical chemistry; powder; RAW 264.7 cell line; Saccharomyces boulardii; Saccharomyces cerevisiae; yeast fermented cabbage; animal; Brassica; chemistry; fermentation; mouse; Saccharomyces cerevisiae | English | 2023 | 2023-10 | 10.4014/jmb.2302.02025 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Quantification of Allantoin in Yams (Dioscorea sp.) Using a 1H NMR Spectroscopic Method | Allantoin is an abundant component of yams and has been known as a skin protectant due to its pharmacological activities. In previous methods for allantoin determination using high-performance liquid chromatography (HPLC), the separation was unsatisfactory. We herein developed a 1H quantitative nuclear magnetic resonance (qNMR) method for quantification of allantoin in the flesh and peel of yams. The method was carried out based on the relative ratio of signals integration of allantoin to a certain amount of the internal standard dimethyl sulfone (DMSO2) and validated in terms of specificity, linearity (range 62.5-2000 mu g/ml), sensitivity (limit of detection (LOD) and quantification (LOQ) 4.63 and 14.03 mu g/ml, respectively), precision (RSD% 0.02-0.26), and recovery (86.35-92.11%). The method was then applied for the evaluation of allantoin in flesh and peel extracts of four different yams cultivated in Korea. | Cao, Thao Quyen; Hahn, Dongyup | Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Integrat Biotechnol, Daegu 41566, South Korea | Quyen, Cao/AAP-9678-2020 | 56937820500; 36554163400 | dohahn@knu.ac.kr; | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | J MICROBIOL BIOTECHN | 1017-7825 | 1738-8872 | 33 | 5 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0.69 | 2025-06-25 | 5 | 4 | Allantoin; yam; Dioscorea; NMR; qNMR; quantitation | PERFORMANCE LIQUID-CHROMATOGRAPHY; QUANTITATIVE-ANALYSIS; H-1-NMR; MODEL; ACID; SKIN | Allantoin; Dioscorea; NMR; qNMR; quantitation; yam | Allantoin; Chromatography, High Pressure Liquid; Dioscorea; Limit of Detection; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; allantoin; allantoin; animal experiment; animal model; antidiabetic activity; antihypertensive activity; antiinflammatory activity; antioxidant activity; Article; controlled study; Dioscorea alata; Dioscorea bulbifera; Dioscorea esculenta; Dioscorea polystachya; drug structure; Fourier transform; high performance liquid chromatography; hypertension; limit of detection; limit of quantitation; mouse; nonhuman; proton nuclear magnetic resonance; species cultivation; spontaneously hypertensive rat; yam; chemistry; nuclear magnetic resonance spectroscopy; procedures; proton nuclear magnetic resonance | English | 2023 | 2023-05 | 10.4014/jmb.2301.01009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Quantitative Label-free Determination of Thrombin Using a Chemically-modified M13 Virus-electrode Interface | The use of affinity peptide displaying on the surface of M13 phage has emerged as a promising alternative to antibody-based detection methods owing to its diverse structure, mass production, easy purification, and genetic manipulation, as well as excellent stability. In this study, we aimed to identify highly selective and sensitive peptide-displayed M13 phage for thrombin detection using phage display technology. Phage display was conducted using two different phage libraries (linear and cyclic forms of peptides), which displayed affinity peptides capable of binding specifically to thrombin. Throughout the biopanning process, two phage clones that displayed both peptides (WGQSFWGYQHYS and CWKLLTPWC) were selected. After the characterization of their binding abilities using enzyme-linked immunosorbent assay, whole phage particles were covalently attached to a gold electrode using MUA-EDC/NHS coupling chemistry. The thrombin detection mechanism was based on signal inhibition, and the results revealed that the specific interactions between the phage-tethered gold electrode and thrombin are critical factors affecting the decrease in the peak current of the sensor. In addition, under optimal conditions, the fabricated phage-based electrochemical sensors were capable of highly sensitive and specific thrombin detection with a good binding affinity (K-d = 17 nM for 12mer 3-17 and 14 nM for C7C 3-5) and limit of detection (4 nM for 12mer 3-17 and 10 nM for C7C 3-5), resulting in good reproducibility, even in artificial human plasma samples. This study may provide an alternative and more efficient method of detecting thrombin with desirable sensitivity, selectivity, and feasibility for the diagnosis and prognosis of coagulation disorder-related diseases. | Shin, Jae Hwan; Yang, Hyo Jeong; Kim, Ji Hong; Yang, Jin Chul; Park, Jinyoung; Park, Jong Pil | Chung Ang Univ, Dept Food Sci & Technol, Basic Res Lab, Anseong 17546, South Korea; Kyungpook Natl Univ, Dept Polymer Sci & Engn, Daegu 41566, South Korea | PARK, JUN-YOUNG/P-5981-2015; Park, Tae/G-1509-2013 | 57223967488; 57975967300; 57195222340; 56381794400; 57286293400; 9270334400 | jinpark@knu.ac.kr;jppark@cau.ac.kr; | BIOTECHNOLOGY AND BIOPROCESS ENGINEERING | BIOTECHNOL BIOPROC E | 1226-8372 | 1976-3816 | 28 | 2 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2023 | 2.5 | 58.3 | 1.06 | 2025-06-25 | 7 | 7 | thrombin; phage display; M13 phage; affinity peptide; electrochemical sensor | APTAMER; BACTERIOPHAGE; BLOOD | affinity peptide; electrochemical sensor; M13 phage; phage display; thrombin | Binding energy; Chemical detection; Diagnosis; Electrochemical biosensors; Electrochemical electrodes; Enzyme electrodes; Gold; Viruses; cysteine; cysteinyltryptophanyllysylleucylleucylthreonylprolyltryptophanylcysteine; peptide; thrombin; tryptophanylglycylglutaminylserylphenylalanyltryptophanylglycyltyrosylglutaminylhistidyltyrosylserine; unclassified drug; Affinity peptides; Chemically modified; Detection methods; Electrode interface; Gold electrodes; Label free; M13 phages; M13 virus; Phage-display; Thrombin; amino acid sequence; Article; binding affinity; biopanning; clone; controlled study; cross coupling reaction; diffusion; diffusion coefficient; electrochemical analysis; Enterobacteria phage M13; enzyme linked immunosorbent assay; feasibility study; human; hydrophobicity; immobilization; limit of detection; molecular docking; nonhuman; peptide library; phage display; prognosis; protein expression; protein expression level; protein function; quantitative analysis; relative binding affinity; sensitivity and specificity; surface area; surface property; validation process; Peptides | English | 2023 | 2023-04 | 10.1007/s12257-022-0361-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Role of Interleukin(IL)-6 in NK Activity to Hypoxic-Induced Highly Invasive Hepatocellular Carcinoma(HCC) Cells | Natural killer (NK) cell dysfunctions against hepatocellular carcinoma (HCC) in a hypoxic environment. Many solid tumors are present in a hypoxic condition, which changes the effector function of various immune cells. The transcription of hypoxic-inducible factors (HIFs) in cancer cells make it possible to adapt to their hypoxic environment and to escape the immune surveillance of NK cells. Recently, the correlation between the transcription of HIF-1a and pro-inflammatory cytokines has been reported. Interleukin (IL)-6 is higher in cancers with a highly invasive ability, and is closely related to the metastasis of cancers. This study showed that the expression of HIF-1 alpha in HCC cells was associated with the presence of IL-6 in the environment of HCC-NK cells. Blocking of IL-6 by antibody in the HCCNK interaction changed the production of several cytokines including TGF-beta, IL-1, IL-18 and IL-21. Interestingly, in a co-culture of HIF-1 alpha-expressed HCC cells and NK cells, blocking of IL-6 increased the production of IL-21 in their supernatants. In addition, the absence of IL-6 significantly enhanced the cytotoxic ability and the expression of the activating receptors (NKG2D, NKp44, and NKG2C) in NK cells to HIF-1 alpha-expressed HCC cells. These effects might be made by the decreased expression of HIF-1 alpha in HCC cells through the inhibited phosphorylation of STAT3. In conclusion, the absence of IL 6 in the interaction of HIF-1 alpha-expressed HCC cells and NK cells could enhance the antitumor activity of NK cells to HCC cells. | Lee, Hwan Hee; Kang, Hyojung; Cho, Hyosun | Duksung Womens Univ, Dept Pharm, Seoul 01369, South Korea; Duksung Womens Univ, Duksung Innovat Drug Ctr, Seoul 01369, South Korea; Kyungpook Natl Univ, Canc Res Inst, Vessel Organ Interact Res Ctr, Coll Pharm,VOICE MRC, Daegu 41566, South Korea | 56271051000; 58507635200; 55572361200 | oeo3oeo@gmail.com;hyosun1102@duksung.ac.kr; | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | J MICROBIOL BIOTECHN | 1017-7825 | 1738-8872 | 33 | 7 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2023 | 2.5 | 58.3 | 1.03 | 2025-06-25 | 5 | 6 | Natural killer (NK) cell; Hepatocellular carcinoma (HCC); hypoxia; HIF-1 & alpha;; Interleukin (IL)-6 | NATURAL-KILLER-CELLS; CD8(+) T-CELLS; RECEPTOR; INHIBITION; MECHANISMS; PATHWAYS; INNATE; TARGET; PD-L1 | Hepatocellular carcinoma (HCC); Hypoxia, HIF-1α; Interleukin (IL)-6; Natural killer (NK) cell | Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Interleukin-6; Interleukins; Liver Neoplasms; Signal Transduction; hypoxia inducible factor 1alpha; interleukin 1; interleukin 18; interleukin 21; interleukin 6; STAT3 protein; transforming growth factor beta; cytokine; interleukin 6; antineoplastic activity; Article; cell function; cell interaction; cell mediated cytotoxicity; coculture; controlled study; cytokine production; enzyme activation; hepatocellular carcinoma cell line; human; human cell; hypoxia; liver cell carcinoma; natural killer cell; protein degradation; protein expression; protein function; protein phosphorylation; protein protein interaction; tumor invasion; tumor microenvironment; liver tumor; pathology; signal transduction; tumor cell line | English | 2023 | 2023-07 | 10.4014/jmb.2304.04023 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Structural and Biochemical Analysis of 3-Dehydroquinate Dehydratase from Corynebacterium glutamicum | Dehydroquinate dehydratase (DHQD) catalyzes the conversion of 3-dehydroquinic acid ( DHQ) into 3-dehydroshikimic acid in the mid stage of the shikimate pathway, which is essential for the biosynthesis of aromatic amino acids and folates. Here, we report two the crystal structures of type II DHQD (CgDHQD) derived from Corynebacterium glutamicum, which is a widely used industrial platform organism. We determined the structures for CgDHQD(WT) with the citrate at a resolution of 1.80A and CgDHQDR19A with DHQ complexed forms at a resolution of 2.00 angstrom, respectively. The enzyme forms a homododecamer consisting of four trimers with three interfacial active sites. We identified the DHQ-binding site of CgDHQD and observed an unusual binding mode of citrate inhibitor in the site with a half- opened lid loop. A structural comparison of CgDHQD with a homolog derived from Streptomyces coelicolor revealed differences in the terminal regions, lid loop, and active site. Particularly, CgDHQD, including some Corynebacterium species, possesses a distinctive residue P105, which is not conserved in other DHQDs at the position near the 5-hydroxyl group of DHQ. Replacements of P105 with isoleucine and valine, conserved in other DHQDs, caused an approximately 70% decrease in the activity, but replacement of S103 with threonine (CgDHQD(S103T)) caused a 10% increase in the activity. Our biochemical studies revealed the importance of key residues and enzyme kinetics for wild type and CgDHQD(S103T), explaining the effect of the variation. This structural and biochemical study provides valuable information for understanding the reaction efficiency that varies due to structural differences caused by the unique sequences of CgDHQD. | Lee, Chan Hwi; Kim, Sangwoo; Seo, Hogyun; Kim, Kyung-Jin | Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioResearch Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, KNU Inst Microorganisms, Daegu, South Korea | Kim, Kyung-Jin/MVY-3405-2025 | 58793060800; 59237076700; 57189697998; 55510867400 | kkim@knu.ac.kr; | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | J MICROBIOL BIOTECHN | 1017-7825 | 1738-8872 | 33 | 12 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0 | 2025-06-25 | 0 | 0 | 3-Dehydroquinate dehydratase; Corynebacterium glutamicum ATCC 13032; shikimate pathway; chorismate biosynthesis | SHIKIMATE PATHWAY; II DEHYDROQUINASE; ESCHERICHIA-COLI; AMINO-ACIDS; MECHANISM; TRYPTOPHAN; SEQUENCE; DATABASE; GENOME; ENZYME | 3-Dehydroquinate dehydratase; chorismate biosynthesis; Corynebacterium glutamicum ATCC 13032; shikimate pathway | Binding Sites; Citrates; Corynebacterium glutamicum; Hydro-Lyases; 3 dehydroquinate dehydratase; chorismic acid; citric acid; hydroxyl group; isoleucine; protein p105; shikimic acid; threonine; valine; 3-dehydroquinate dehydratase; hydrolyase; Article; bacterial strain; binding site; biochemical analysis; controlled study; Corynebacterium glutamicum; crystal structure; enzyme active site; enzyme activity; enzyme kinetics; enzyme structure; microbial activity; nonhuman; protein expression; Streptomyces coelicolor; structure analysis; wild type; chemistry; genetics; metabolism | English | 2023 | 2023-12 | 10.4014/jmb.2305.05018 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | The Forkhead Gene fkhB is Necessary for Proper Development in Aspergillus nidulans | The forkhead domain genes are important for development and morphogenesis in fungi. Six forkhead genes fkhA-fkhF have been found in the genome of the model filamentous Ascomycete Aspergillus nidulans. To identify the fkh gene(s) associated with fungal development, we examined mRNA levels of these six genes and found that the level of fkhB and fkhD mRNA was significantly elevated during asexual development and in conidia. To investigate the roles of FkhB and FkhD, we generated fkhB and fkhD deletion mutants and complemented strains and investigated their phenotypes. The deletion of fkhB, but not fkhD, affected fungal growth and both sexual and asexual development. The fkhB deletion mutant exhibited decreased colony size with distinctly pigmented (reddish) asexual spores and a significantly lower number of conidia compared with these features in the wild type (WT), although the level of sterigmatocystin was unaffected by the absence of fkhB. Furthermore, the fkhB deletion mutant produced sexual fruiting bodies (cleistothecia) smaller than those of WT, implying that the fkhB gene is involved in both asexual and sexual development. In addition, fkhB deletion reduced fungal tolerance to heat stress and decreased trehalose accumulation in conidia. Overall, these results suggest that fkhB plays a key role in proper fungal growth, development, and conidial stress tolerance in A. nidulans. | Jang, Seo-Yeong; Son, Ye-Eun; Oh, Dong-Soon; Han, Kap-Hoon; Yu, Jae-Hyuk; Park, Hee-Soo | Kyungpook Natl Univ, Dept Integrat Biol, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Woosuk Univ, Dept Pharmaceut Engn, Wonju 55338, South Korea; Univ Wisconsin Madison, Dept Bacteriol, Madison, WI 53706 USA | Park, Hee-Soo/AAC-6422-2019; Yu, Jae-Hyuk/A-2343-2008 | 57224108380; 57200513491; 55018119600; 22947495900; 7405531243; 15751448400 | phsoo97@knu.ac.kr; | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | J MICROBIOL BIOTECHN | 1017-7825 | 1738-8872 | 33 | 11 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0.69 | 2025-06-25 | 4 | 4 | Forkhead domain; fkhB; asexual development; sterigmatocystin; Aspergillus nidulans | TRANSCRIPTION FACTORS; ASEXUAL SPORULATION; YEAST; BIOSYNTHESIS; BINDING; ACFKH1; DOMAIN; CPCR1 | asexual development; Aspergillus nidulans; fkhB; Forkhead domain; sterigmatocystin | Aspergillus nidulans; Fungal Proteins; Gene Expression Regulation, Fungal; Phenotype; RNA, Messenger; Spores, Fungal; forkhead transcription factor; sterigmatocystin; trehalose; fungal protein; messenger RNA; Article; asexual spore; Aspergillus nidulans; cleistothecia; conidium; controlled study; fkhB gene; FkhD gene; gene; gene deletion; gene identification; heat stress; heat tolerance; morphogenesis; mRNA expression level; nonhuman; phenotype; physiological stress; sexual development; fungus spore; gene expression regulation; genetics; metabolism | English | 2023 | 2023-11 | 10.4014/jmb.2307.07009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | The In Vivo and In Vitro Effects of Terminalia bellirica (Gaertn.) Roxb. Fruit Extract on Testosterone-Induced Hair Loss | Due to the continuous increase in patients with androgenetic alopecia (AGA) and psychological disorders such as depression and anxiety, the demand for hair loss treatment and effective hair growth materials has increased. Terminalia bellirica (Gaertn.) Roxb. (TBE) reportedly exerts antiinflammatory, hepatoprotective, and anti-diabetic effects, among others, but its effects on testosterone (TS)-inhibited hair growth remains unclear. In this study, we evaluated the effects of TBE on TS-induced hair growth regression in human follicle dermal papilla cells (HFDPCs) and C57BL/6 mice. Oral administration of TBE increased TS-induced hair growth retardation. Interestingly, effects were greater when compared with finasteride, a commercial hair loss treatment product. Histological analyses revealed that oral TBE administration increased hair follicles in the dorsal skin of C57BL/6 mice. Additionally, western blotting and immunofluorescence showed that oral TBE administration recovered the TS-induced inhibition of cyclin D1, proliferating cell nuclear antigen (PCNA), and Ki67 expression in vivo. Using in vitro proliferation assays, TBE promoted HFDPC growth, which was suppressed by TS treatment. Thus, TBE may be a promising nutraceutical for hair health as it promoted hair growth in AGA-like in vitro and in vivo models. | Woo, Min Jeong; Kang, Ha Yeong; Paik, So Jeong; Choi, Hee Jung; Uddin, Salah; Lee, Sangwoo; Kim, Soo-Yong; Choi, Sangho; Jung, Sung Keun | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Ethnobot Database Bangladesh EDB, 7-I BFDC Rd, Dhaka 1208, Bangladesh; Korea Res Inst Biosci & Biotechnol, Int Biol Mat Res Ctr, Daejeon 34141, South Korea; Kyungpook Natl Univ, Res Inst Tailored Food Technol, Daegu 41566, South Korea | Uddin, Md Salah/JQI-7925-2023; Jung, SUNG KEUN/AGR-2623-2022; Uddin, Md. Salah/JQI-7925-2023 | 58028839700; 57733176700; 58161897900; 58742906900; 57427883700; 7601398671; 55718671000; 59102027200; 35310491400 | skjung04@knu.ac.kr; | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | J MICROBIOL BIOTECHN | 1017-7825 | 1738-8872 | 33 | 11 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2023 | 2.5 | 58.3 | 0.34 | 2025-06-25 | 2 | 2 | Androgenetic alopecia; human follicle dermal papilla cells; Terminalia bellirica (Gaertn.) Roxb. fruit extract; testosterone; hair growth | WNT; EXPRESSION; ANDROGEN; BETA | Androgenetic alopecia; hair growth; human follicle dermal papilla cells; Terminalia bellirica (Gaertn.) Roxb. fruit extract; testosterone | Alopecia; Animals; Fruit; Hair Follicle; Humans; Mice; Mice, Inbred C57BL; Plant Extracts; Terminalia; Testosterone; beta catenin; cyclin D1; cycline; finasteride; Ki 67 antigen; plant extract; Terminalia bellirica fruit extract; testosterone; unclassified drug; plant extract; animal cell; animal experiment; animal model; animal tissue; Article; C57BL 6 mouse; cell proliferation; cell proliferation assay; controlled study; drug screening; growth inhibition; hair follicle cell; hair growth; hair loss; histopathology; human; human cell; immunofluorescence; in vitro study; in vivo study; male; male type alopecia; mouse; nonhuman; protein expression; Terminalia bellirica; Western blotting; alopecia; animal; C57BL mouse; fruit; hair follicle; Terminalia | English | 2023 | 2023-11 | 10.4014/jmb.2306.06004 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | A standardized pathology report for gastric cancer: 2nd edition | The first edition of 'A Standardized Pathology Report for Gastric Cancer' was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago. Since then, significant advances have been made in the pathologic diagnosis, molecular genetics, and management of gastric cancer (GC). To reflect those changes, a committee for publishing a second edition of the report was formed within the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists. This second edition consists of two parts: standard data elements and conditional data elements. The standard data elements contain the basic pathologic findings and items necessary to predict the prognosis of GC patients, and they are adequate for routine surgical pathology service. Other diagnostic and prognostic factors relevant to adjuvant therapy, including molecular biomarkers, are classified as conditional data elements to allow each pathologist to selectively choose items appropriate to the environment in their institution. We trust that the standardized pathology report will be helpful for GC diagnosis and facilitate large-scale multidisciplinary collaborative studies. | Park, Young Soo; Kook, Myeong-Cherl; Kim, Baek-hui; Lee, Hye Seung; Kang, Dong-Wook; Gu, Mi-Jin; Shin, Ok Ran; Choi, Younghee; Lee, Wonae; Kim, Hyunki; Song, In Hye; Kim, Kyoung-Mee; Kim, Hee Sung; Kang, Guhyun; Park, Do Youn; Jin, So -Young; Kim, Joon Mee; Choi, Yoon Jung; Chang, Hee Kyung; Ahn, Soomin; Chang, Mee Soo; Han, Song-Hee; Kwak, Yoonjin; Seo, An Na; Lee, Sung Hak; Cho, Mee-Yon | Univ Ulsan, Asan Med Ctr, Dept Pathol, Coll Med, Seoul, South Korea; Natl Canc Ctr, Ctr Gastr Canc, Goyang, South Korea; Korea Univ, Dept Pathol, Guro Hosp, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Pathol, Coll Med, Seoul, South Korea; Chungnam Natl Univ, Sejong Hosp, Sch Med, Dept Pathol, Sejong, South Korea; Yeungnam Univ, Dept Pathol, Coll Med, Daegu, South Korea; Catholic Univ Korea, Uijeongbu St Marys Hosp, Dept Hosp Pathol, Coll Med, Uijongbu, South Korea; Hallym Univ, Dongtan Sacred Heart Hosp, Dept Pathol, Hwaseong, South Korea; Dankook Univ, Dept Pathol, Coll Med, Cheonan, South Korea; Yonsei Univ, Dept Pathol, Coll Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Pathol & Translat Genom, Sch Med, Seoul, South Korea; Chung Ang Univ, Chung Ang Univ Hosp, Dept Pathol, Coll Med, Seoul, South Korea; LabGen Clin Labs, Seongnam, South Korea; St Maria Pathol Lab, Busan, South Korea; Soonchunhyang Univ, Dept Pathol, Seoul Hosp, Seoul, South Korea; Inha Univ, Dept Pathol, Sch Med, Incheon, South Korea; Yonsei Univ, Yongin Severance Hosp, Dept Pathol, Coll Med, Yongin, South Korea; Kosin Univ, Gospel Hosp, Dept Pathol, Coll Med, Busan, South Korea; Seoul Natl Univ, Boramae Hosp, Dept Pathol, Coll Med, Seoul, South Korea; Dong A Univ Coll Med, Dept Pathol, Busan, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Catholic Univ Korea, Dept Hosp Pathol, Seoul St Marys Hosp, Coll Med, Seoul, South Korea; Yonsei Univ, Wonju Severance Christian Hosp, Dept Pathol, Wonju Coll Med, Wonju, South Korea | Kook, Moochang/B-7001-2014; Lee, Hye Seung/LZI-3726-2025; Kim, Wooho/G-3703-2011; Kwak, Yoonjin/HOI-0139-2023; Kim, Ju-Hyoung/N-1450-2019 | 55540144700; 7003734725; 16203115900; 57102095800; 55885804400; 55584780700; 8609180500; 55685949600; 55973619400; 57965263900; 57217272410; 56155892100; 58985198500; 35181393000; 57205289656; 35590135600; 57554573600; 57190118469; 12778283700; 54893655800; 7404504590; 59604183800; 56049775700; 55804153700; 57203597873; 7401727574 | hakjjang@catholic.ac.kr;meeyon@yonsei.ac.kr; | JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE | J PATHOL TRANSL MED | 2383-7837 | 2383-7845 | 57 | 1 | ESCI | PATHOLOGY | 2023 | 1.7 | 58.5 | 1.06 | 2025-06-25 | 19 | 11 | Stomach neoplasms; Gastrectomy; Endoscopic resection; Molecular pathology; Pathology report; Standardization | LYMPH-NODE METASTASIS; ENDOSCOPIC SUBMUCOSAL DISSECTION; MISMATCH REPAIR-DEFICIENCY; EXPRESSION-BASED CLASSIFICATION; INDEPENDENT PROGNOSTIC-FACTOR; TUMOR MUTATIONAL BURDEN; FAVORABLE RISK-FACTOR; RING CELL-CARCINOMA; MICROSATELLITE INSTABILITY; CLINICOPATHOLOGICAL FEATURES | Endoscopic resection; Gastrectomy; Molecular pathology; Pathology report; Standardization; Stomach neoplasms | epidermal growth factor receptor 2; molecular marker; mucin; programmed death 1 receptor; tumor marker; cancer classification; cancer grading; cancer localization; cancer regression; cancer size; cancer surgery; en bloc resection; endoscopic surgery; Epstein Barr virus; Epstein Barr virus infection; extranodal extension; gastrectomy; Helicobacter infection; Helicobacter pylori; high throughput sequencing; histopathology; human; immunohistochemistry; lymph node metastasis; lymph vessel metastasis; microsatellite instability; mismatch repair; molecular pathology; nonhuman; perineural invasion; phenotype; radical resection; regional metastasis; Review; standardization; stomach adenoma; stomach biopsy; stomach cancer; stomach ulcer; surgical margin; tissue section; tumor biopsy; tumor depth; tumor localization; tumor regression; tumor volume | English | 2023 | 2023-01 | 10.4132/jptm.2022.12.23 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Diagnostic proficiency test using digital cytopathology and comparative assessment of whole slide images of cytologic samples for quality assurance program in Korea | Background: The Korean Society for Cytopathology introduced a digital proficiency test (PT) in 2021. However, many doubtful opinions remain on whether digitally scanned images can satisfactorily present subtle differences in the nuclear features and chromatin patterns of cytological samples. Methods: We prepared 30 whole-slide images (WSIs) from the conventional PT archive by a selection process for digital PT. Digital and conventional PT were performed in parallel for volunteer institutes, and the results were compared using feed-back. To assess the quality of cytological assessment WSIs, 12 slides were collected and scanned using five different scanners, with four cytopathologists evaluating image quality through a questionnaire. Results: Among the 215 institutes, 108 and 107 participated in glass and digital PT, respectively. No significant difference was noted in category C (major discordance), although the number of discor-dant cases was slightly higher in the digital PT group. Leica, 3DHistech Pannoramic 250 Flash, and Hamamatsu NanoZoomer 360 sys-tems showed comparable results in terms of image quality, feature presentation, and error rates for most cytological samples. Overall satisfaction was observed with the general convenience and image quality of digital PT. Conclusions: As three-dimensional clusters are common and nuclear/chromatin features are critical for cytological interpretation, careful selection of scanners and optimal conditions are mandatory for the successful establishment of digital quality assurance programs in cytology. | Chong, Yosep; Hong, Soon Auck; Oh, Hoon Kyu; Jung, Soo Jin; Kim, Bo-Sung; Jeong, Ji Yun; Lee, Ho-Chang; Gong, Gyungyub | Catholic Univ Korea, Dept Hosp Pathol, Coll Med, Seoul, South Korea; Chung Ang Univ, Coll Med, Dept Pathol, Seoul, South Korea; Daegu Catholic Univ, Sch Med, Dept Pathol, Daegu, South Korea; Inje Univ, Busan Paik Hosp, Dept Pathol, Busan, South Korea; Green Cross Labs, Dept Pathol, Yongin, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Chungbuk Natl Univ, Coll Med, Dept Pathol, Cheongju, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pathol, Seoul, South Korea | Kim, Byung Joo/ABG-7715-2021; Chong, Yosep/AAC-5784-2021; Lee, Han/W-4924-2019 | 23666142300; 35181418800; 8863253400; 35247881800; 57191338772; 57205472984; 34872617200; 7103214892 | ychong@catholic.ac.kr; | JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE | J PATHOL TRANSL MED | 2383-7837 | 2383-7845 | 57 | 5 | ESCI | PATHOLOGY | 2023 | 1.7 | 58.5 | 1.13 | 2025-06-25 | 4 | 4 | Cytology; Quality assurance; Digital pathology; Whole-slide image; Whole-slide scanner | Cytology; Digital pathology; Quality assurance; Whole-slide image; Whole-slide scanner | Article; chromatin; comparative study; controlled study; cytology; cytopathologist; cytopathology; digital pathology; human; human tissue; image quality; Korea; quality control; questionnaire; satisfaction; tissue section | English | 2023 | 2023-09 | 10.4132/jptm.2023.07.17 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Manufacturing of Filament for 4D Printing through Polyether-Type TPU/PLA Blend | Reversible deformation structure fabricated by 4D printing can be applied in various fields, such as actuators, intelligent mechanisms, and soft robots. In this study, 4D filaments for use in fused deposition modeling (FDM) 3D printers were fabricated by melt extrusion process mixing polylactic acid (PLA) and soft actuator grade thermoplastic polyurethane (TPU) 75 Shore A. The morphological (scanning electron microscopy, atomic force microscopy), chemical (Fourier transform infrared), thermal (differential scanning calorimetry, dynamic mechanical analysis, thermogravimetric analysis), mechanical (Instron), and WAXS properties of the prepared TPU/PLA blend (5 : 5, 7 : 3, 9 : 1) filaments were investigated. Filaments of 4D auxetic reentrant TPU/PLA samples were 3D printed, and their shape-memory characteristics were assessed at temperatures of 60 degrees C (corresponding to the glass transition temperature of PLA), 70 degrees C, 80 degrees C (matching the melting temperature of the soft segment of TPU), and 90 degrees C. The properties of TPU/PLA samples differ based on the PLA to TPU ratio, with an increase in TPU content resulting in a higher shape setting temperature but a shorter shape recovery time. For the TPU/PLA 5 : 5 sample, setting at 70 degrees C and recovering at 85 degrees C is the most suitable condition for shape recovery, whereas for the TPU/PLA 7 : 3 sample the best conditions are setting at 80 degrees C and recovering at 95 degrees C. In the case of TPU/PLA 9 : 1, shape setting is possible at 90 degrees C, and shape recovery is fastest at 95 degrees C. A 4D structure of TPU/PLA could be achieved based on shape memory testing by temperature stimulation of 3D printed auxetic c TPU/PLA samples. | Shin, Eun Joo; Song, Ye Jin; Jung, Yang Sook; Jung, Imjoo; Lee, Sunhee | Dong A Univ, Dept Chem Engn, Pusan 55037, South Korea; Kyungpook Natl Univ, Dept Biofibers & Biomat Sci, Daegu 41566, South Korea; Dong A Univ, Dept Fash Design, Busan 55037, South Korea | 55984568700; 58724532300; 57802210500; 57203408880; 57207067693 | sejoo6313@dau.ac.kr;syj980224@naver.com;9jungys@gmail.com;imjoo629@naver.com;shlee014@dau.ac.kr; | ADVANCES IN POLYMER TECHNOLOGY | ADV POLYM TECH | 0730-6679 | 1098-2329 | 2023 | SCIE | ENGINEERING, CHEMICAL;POLYMER SCIENCE | 2023 | 2 | 58.5 | 0.53 | 2025-06-25 | 4 | 4 | THERMOPLASTIC POLYURETHANES; CHEMICAL-STRUCTURE; THERMAL-PROPERTIES; MOLECULAR-WEIGHT; MORPHOLOGY; BEHAVIOR; OIL; ELASTOMERS; POLYOLS | Actuators; Blending; Glass transition; Melt spinning; Recovery; Scanning electron microscopy; Shape optimization; Thermogravimetric analysis; Auxetics; Deformation structure; Intelligent mechanisms; Melt extrusion process; Property; Reversible deformation; Shape recovery; Soft actuators; Soft robot; Thermoplastic polyurethanes; Differential scanning calorimetry | English | 2023 | 2023-11-10 | 10.1155/2023/4875625 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | Meeting Abstract | A microglial innate immune protein PGLYRP1 mediates neuroinflammation | Bhusal, A.; Kim, J.; Hwang, E. M.; Sung, Y. K.; Suk, K. | Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Daegu, South Korea; Korea Inst Sci & Technol, Brain Sci Inst, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Immunol, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, Daegu, South Korea | Hwang, Eun Mi/HHN-3030-2022 | FEBS OPEN BIO | FEBS OPEN BIO | 2211-5463 | 13 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2023 | 2.8 | 58.6 | 0 | English | 2023 | 2023-07 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | Meeting Abstract | Crystal structure and functional characterization of acetylornithine aminotransferase from Corynebacterium glutamicum | Ki, D.; Kim, K. | Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioRes Grp, Daegu, South Korea | Kim, Kyung-Jin/MVY-3405-2025 | FEBS OPEN BIO | FEBS OPEN BIO | 2211-5463 | 13 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2023 | 2.8 | 58.6 | 0 | English | 2023 | 2023-07 | 바로가기 | 바로가기 |
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