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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | φ Meson Photoproduction on the Nucleon and ⁴He Targets | We study the reaction mechanism of phi-meson photoproduction on the nucleon and He-4 targets by using a dynamical model based on a Hamiltonian. In addition to the dominant contribution of the Pomeron exchange, various meson exchanges are considered in the t channel to describe the CLAS data in the low energy region root s =(1.97-2.84) GeV. The direct phi radiations are taken into account in the s- and u-channels. The backward structures at root s approximate to 2.1 and 2.3 GeV are well reproduced by the inclusion of the s-channel N(2000,5/2(+)) and N(2300,1/2(+))resonances, respectively. We also consider the final phi N interactions by the gluon exchange, the direct phi N interactions, and the box diagrams arising from the couplings with the pi N, rho N, K Lambda, and K Sigma channels. The effects of the final state interactions are found to be very weak. Then the resulting Hamiltonian is used to study the coherent gamma He-4 -> phi He-4 reaction within the distorted-weave impulse approximation. The calculated differential cross sections account for the LEPS data quite well. | Kim, Sang-Ho; Lee, T. - S. H.; Nam, Seung-Il; Oh, Yongseok | Soongsil Univ, Dept Phys, Seoul 06978, South Korea; Soongsil Univ, Origin Matter & Evolut Galaxy OMEG Inst, Seoul 06978, South Korea; Argonne Natl Lab, Phys Div, Argonne, IL 60439 USA; Pukyong Natl Univ, Dept Phys, Busan 48513, South Korea; Asia Pacific Ctr Theoret Phys, Pohang 37673, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea | 54398870900; 8745480200; 7402275945; 7402125873 | shkimphy@gmail.com;tshlee@anl.gov;sinam@pknu.ac.kr;yohphy@knu.ac.kr; | FEW-BODY SYSTEMS | FEW-BODY SYST | 0177-7963 | 1432-5411 | 65 | 2 | SCIE | PHYSICS, MULTIDISCIPLINARY | 2024 | 1.8 | 46.9 | 0 | 2025-05-07 | 0 | 0 | English | 2024 | 2024-03-10 | 10.1007/s00601-024-01894-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | The effect of different mechanical retention forms on shear bond strength of rebonding of ceramic brackets | The objective of this study is to compare the shear bond strength (SBS) and the morphological characteristics and chemical compositions of the base surface of newly bonded and rebonded ceramic brackets with different mechanical retention bases. Sixty extracted human premolars were divided into the newly bonded and rebonded groups. Ceramic brackets with patterned, laser-etched, and particlecoated patterned bases were randomly bonded to the tooth samples in each group (n=10 per base type). The rebonded brackets exhibited significantly lower SBS than the newly bonded brackets (p<0.05). The main chemical composition of the brackets in both groups was aluminum on the energy-dispersive X-ray spectroscopy. Scanning electron microscopy imaging showed the presence of regular-shaped undercuts or irregular micro-undercuts on the bracket bases which mostly remained intact even after debonding and sandblasting, while coated particles disappeared. The rebonded ceramic brackets with mechanical retention bases exhibited clinically acceptable bond strength regardless of retentive forms. | Kim, Ho-Jin; Kwon, Tae-Yub; Noh, Hyung-Kyu; Park, Hyo-Sang | Kyungpook Natl Univ, Sch Dent, Dept Orthodont, Daegu, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Dent Biomat, Daegu, South Korea | 57200084686; 7202206084; 57208229164; 55754836800 | parkhs@knu.ac.kr; | DENTAL MATERIALS JOURNAL | DENT MATER J | 0287-4547 | 43 | 1 | SCIE | DENTISTRY, ORAL SURGERY & MEDICINE;MATERIALS SCIENCE, BIOMATERIALS | 2024 | 1.9 | 47.2 | 0 | 2025-04-16 | 1 | 0 | Rebonding; Ceramic bracket; Bond strength; Mechanical retention form | ORTHODONTIC BRACKETS; IN-VIVO; ENAMEL; FAILURE | Bond strength; Ceramic bracket; Mechanical retention form; Rebonding | Aluminum Oxide; Ceramics; Dental Bonding; Humans; Materials Testing; Orthodontic Brackets; Shear Strength; Surface Properties; Bond strength (materials); Energy dispersive spectroscopy; Shear flow; aluminum oxide; Base surface; Bond strength; Ceramic bracket; Chemical compositions; Energy dispersive X ray spectroscopy; Mechanical retention; Mechanical retention form; Morphological characteristic; Rebonding; Shear bond strengths; ceramics; chemistry; dental bonding; human; materials testing; procedures; shear strength; surface property; Scanning electron microscopy | English | 2024 | 2024-02 | 10.4012/dmj.2023-164 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Follow-up strategy for early detection of delayed pseudoaneurysms in patients with blunt traumatic spleen injury: A single-center retrospective study | BACKGROUND The spleen is the most commonly injured solid organ in blunt abdominal trauma, and splenic pseudoaneurysm rupture is associated with a high risk of mortality. Nonoperative management has become the standard treatment for hemodynamically stable patients with splenic injuries. On the other hand, delayed splenic pseudoaneurysms can develop in any patient, and at present, there are no known risk factors that may reliably predict their occurrence. Furthermore, there is a lack of consensus regarding the most appropriate strategies for monitoring and managing splenic injuries, especially lower-grade (I-III). AIM To determine the predictors of pseudo-aneurysm formation following splenic injury and develop follow-up strategies for early detection of pseudoaneurysms. METHODS We retrospectively analyzed patients who visited the Level I Trauma Center between January 2013 and December 2022 and were diagnosed with spleen injuries after blunt abdominal trauma. RESULTS Using the American Association for the Surgery of Trauma spleen injury scale, the splenic injuries were categorized into the following order based on severity: Grade I (n = 57, 17.6%), grade II (n = 114, 35.3%), grade III (n = 89, 27.6%), grade IV (n = 50, 15.5%), and grade V (n = 13, 4.0%). Of a total of 323 patients, 35 underwent splenectomy and 126 underwent angioembolization. 19 underwent delayed angioembolization, and 5 under-went both initial and delayed angioembolization. In 14 patients who had undergone delayed angioembolization, no extravasation or pseudoaneurysm was observed on the initial computed tomography scan. There are no particular patient-related risk factors for the formation of a delayed splenic pseudoaneurysm, which can occur even in a grade I spleen injury or even 21 days after the injury. The mean detection time for a delayed pseudoaneurysm was 6.26 +/- 5.4 (1-21, median: 6, interquartile range: 2-9) days. CONCLUSION We recommend regular follow-up computed tomography scans, including an arterial and portal venous phase, at least 1 week and 1 month after injury in any grade of blunt traumatic spleen injury for the timely detection of delayed pseudoaneurysms. | Cho, Sung Hoon; Kim, Gun Woo; Hwang, Suyeong; Lim, Kyoung Hoon | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Surg,Trauma Ctr, 130 Dongduk Ro, Daegu 41944, South Korea | drlimkh@knu.ac.kr; | WORLD JOURNAL OF GASTROINTESTINAL SURGERY | WORLD J GASTRO SURG | 1948-9366 | 16 | 10 | SCIE | GASTROENTEROLOGY & HEPATOLOGY;SURGERY | 2024 | 1.7 | 47.3 | 1 | Blunt trauma; Spleen injury; Delayed pseudoaneurysm; Angioembolization; Nonoperative management | SPLENIC ARTERY PSEUDOANEURYSMS; NONOPERATIVE MANAGEMENT; ABDOMINAL-TRAUMA; EMBOLIZATION; CT | English | 2024 | 2024-10-27 | 10.4240/wjgs.v16.i10.3163 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
| ○ | ○ | Article | Practice guidelines for managing extrahepatic biliary tract cancers | Backgrounds/Aims: Reported incidence of extrahepatic bile duct cancer is higher in Asians than in Western populations. Korea, in particular, is one of the countries with the highest incidence rates of extrahepatic bile duct cancer in the world. Although research and innovative therapeutic modalities for extrahepatic bile duct cancer are emerging, clinical guidelines are currently unavailable in Korea. The Korean Society of Hepato-Biliary-Pancreatic Surgery in collaboration with related societies (Korean Pancreatic and Biliary Surgery Society, Korean Society of Abdominal Radiology, Korean Society of Medical Oncology, Korean Society of Radiation Oncology, Korean Society of Pathologists, and Korean Society of Nuclear Medicine) decided to establish clinical guideline for extrahepatic bile duct cancer in June 2021. Methods: Contents of the guidelines were developed through subgroup meetings for each key question and a preliminary draft was finalized through a Clinical Guidelines Committee workshop. Results: In November 2021, the finalized draft was presented for public scrutiny during a formal hearing. Conclusions: The extrahepatic guideline committee believed that this guideline could be helpful in the treatment of patients. | Kim, Hyung Sun; Kang, Mee Joo; Kang, Jingu; Kim, Kyubo; Kim, Bohyun; Kim, Seong-Hun; Kim, Soo Jin; Kim, Yong-Il; Kim, Joo Young; Kim, Jin Sil; Kim, Haeryoung; Kim, Hyo Jung; Nahm, Ji Hae; Park, Won Suk; Park, Eunkyu; Park, Joo Kyung; Park, Jin Myung; Song, Byeong Jun; Shin, Yong Chan; Ahn, Keun Soo; Woo, Sang Myung; Yu, Jeong Il; Yoo, Changhoon; Lee, Kyoungbun; Lee, Dong Ho; Lee, Myung Ah; Lee, Seung Eun; Lee, Ik Jae; Lee, Huisong; Im, Jung Ho; Jang, Kee-Taek; Jang, Hye Young; Jun, Sun -Young; Chon, Hong Jae; Jung, Min Kyu; Chung, Yong Eun; Chong, Jae Uk; Cho, Eunae; Chie, Eui Kyu; Choi, Sae Byeol; Choi, Seo-Yeon; Choi, Seong Ji; Choi, Joon Young; Choi, Hye-Jeong; Hong, Seung-Mo; Hong, Ji Hyung; Hong, Tae Ho; Hwang, Shin Hye; Hwang, In Gyu; Park, Joon Seong | Yonsei Univ, Coll Med, Dept Surg, Pancreatobiliary Clin, Seoul, South Korea; Natl Canc Ctr, Ctr Liver & Pancreatobiliary Canc, Goyang, South Korea; Hallym Univ, Kangdong Sacred Heart Hosp, Med Ctr, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Radiat Oncol, Seongnam, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Radiol, Seoul, South Korea; Jeonbuk Natl Univ, Med Sch, Dept Internal Med, Jeonju, South Korea; Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Biomed Res Inst, Res Inst Clin Med, Jeonju, South Korea; Natl Canc Ctr, Dept Radiol, Goyang, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Nucl Med, Seoul, South Korea; Hallym Univ, Kangnam Sacred Heart Hosp, Coll Med, Dept Pathol, Seoul, South Korea; Ewha Womans Univ, Sch Med, Dept Radiol, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Pathol, Seoul, South Korea; Korea Univ, Guro Hosp, Dept Internal Med, Seoul, South Korea; Yonsei Univ, Coll Med, Dept Pathol, Seoul, South Korea; Catholic Univ Korea, Daejeon St Marys Hosp, Coll Med, Div Gastroenterol,Dept Internal Med, Daejeon, South Korea; Chonnam Natl Univ Hosp, Dept Surg, Div HBP Surg, Gwangju, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Med, Seoul, South Korea; Kangwon Natl Univ, Sch Med, Dept Internal Med, Chunchon, South Korea; Myongji Hosp, Dept Internal Med, Goyang, South Korea; Inje Univ, Ilsan Paik Hosp, Coll Med, Dept Surg, Goyang, South Korea; Keimyung Univ, Dongsan Hosp, Dept Surg, Div Hepatobiliary & Pancreat Surg, Daegu, South Korea; Natl Canc Ctr, Immuno Oncol Branch, Ctr Liver & Pancreatobiliary Canc, Div Rare ,Res Inst,Hosp, Goyang, South Korea; Natl Canc Ctr, Res Inst, Refractory Ctr, Goyang, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Radiat Oncol, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Oncol, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Radiol, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Div Med Oncol, Seoul, South Korea; Chung Ang Univ, Chung Ang Univ Hosp, Dept Surg, Coll Med, Seoul, South Korea; Yonsei Univ, Coll Med, Yonsei Canc Ctr, Dept Radiat Oncol, Seoul, South Korea; Ewha Womans Univ, Mokdong Hosp, Dept Surg, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Sch Med, Dept Radiat Oncol, Seongnam, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Pathol, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Radiol, Seoul, South Korea; Catholic Univ Korea, Incheon St Marys Hosp, Coll Med, Dept Pathol, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Med Oncol, Sch Med, Seongnam, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Div Gastroenterol & Hepatol,Dept Internal Med, Daegu, South Korea; Yonsei Univ, Severance Hosp, Coll Med, Dept Radiol, Seoul, South Korea; Ilsan Hosp, Dept Surg, Natl Hlth Insurance Serv, Goyang, South Korea; Chonnam Natl Univ, Med Sch, Dept Internal Med, Gwangju, South Korea; Seoul Natl Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Korea Univ, Guro Hosp, Coll Med, Dept Surg, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Radiol, Seoul, South Korea; Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Nucl Med, Seoul, South Korea; Univ Ulsan, Ulsan Univ Hosp, Coll Med, Dept Pathol, Ulsan, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pathol, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Surg, Div Hepatobiliary & Pancreas Surg,Coll Med, Seoul, South Korea; Yonsei Univ, Yongin Severance Hosp, Coll Med, Dept Radiol, Yongin, South Korea; Chung Ang Univ, Chung Ang Univ Hosp, Dept Internal Med, Div Hemato Oncol,Coll Med, Seoul, South Korea | KANG, MIN KYU/ACI-8824-2022; Kim, Jin Sil/S-1359-2019; Choi, Won/V-2730-2017; Jeong, Young-Hoon/F-3476-2015; Han, Jae-Young/AAV-1100-2021; Kim, SooJin/LNP-4493-2024; Lee, Kyoungbun/F-6358-2011; Park, Young-Jae/AAJ-8828-2020; Hong, Ji/ABB-4227-2020; Yu, Jeong Il/MTC-0984-2025; Kim, Byung/L-6884-2019; Kim, Sun/C-2026-2011; Kim, Kyubo/R-8061-2019; Park, Jung Hoon/CZZ-0090-2022 | 57242137600; 23018377700; 57030966000; 8213302900; 57791012600; 57206878084; 59537974200; 58417918500; 57317739100; 57189764787; 35307240200; 56995392900; 57711064700; 58815177000; 41262120600; 57203537385; 57205232842; 57194420427; 56589363600; 59712504100; 14038271300; 35212472500; 22954694200; 50461719000; 57222878418; 35227488700; 35210819100; 36786568600; 56019344700; 56096038400; 10140921200; 57195219819; 7103305476; 25951294300; 56783168100; 57225850256; 57072721700; 57225705236; 7801394373; 35291533800; 59862739600; 57202151295; 8941826200; 56558993300; 58628329900; 57201453850; 7202830520; 56397382400; 7201614898; 57226672001 | jspark330@yuhs.ac; | ANNALS OF HEPATO-BILIARY-PANCREATIC SURGERY | ANN HEPATO-BIL-PANCR | 2508-5778 | 2508-5859 | 28 | 2 | ESCI | GASTROENTEROLOGY & HEPATOLOGY;SURGERY | 2024 | 1.7 | 47.3 | 1.37 | 2025-05-07 | 2 | 2 | Extrahepatic; Bile duct cancer; Guidlines | BILE-DUCT CANCER; PORTAL-VEIN RESECTION; EXPANDABLE METAL STENTS; POSITRON-EMISSION-TOMOGRAPHY; FINE-NEEDLE-ASPIRATION; OPERATOR PERORAL CHOLANGIOSCOPY; HILAR CHOLANGIOCARCINOMA VALUE; CAUDATE LOBE RESECTION; FUTURE LIVER REMNANT; LONG-TERM SURVIVAL | Bile duct cancer; Extrahepatic; Guidlines | English | 2024 | 2024-05 | 10.14701/ahbps.23-170 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Successive Development and Rupture of Blister-Like Anterior Communicating Artery Aneurysms at Mirror Locations | This is the first report of the successive development and rupture of blister-like anterior communicating artery (ACoA) aneurysms at mirror locations with a short interval. A 49-year-old man presented with an angiogram-negative subarachnoid hemorrhage with significant basal frontal interhemispheric blood. Surgical exploration revealed a blister-like aneurysm on the left side of the superior wall of the ACoA, which was treated using a microsuturing technique. On the 18th day after the initial subarachnoid hemorrhage, the second operation due to another angiogram-negative hemorrhage revealed a de novo blister-like aneurysm with a small blood clot on the posterosuperior wall of the ACoA close to the right A1/A2 junction. The rupture point and ACoA on the right side were occluded using an aneurysm clip. Follow-up digital subtraction angiogram at 4 years and computed tomography angiogram at 14 years after the surgery showed no recurrence or associated abnormality. | Kim, Myungsoo; Park, Jaechan | Kyungpook Natl Univ, Sch Med, Dept Neurosurg, Daegu, South Korea | 57210943611; 44661451000 | jparkmd@hotmail.com; | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY | J KOREAN NEUROSURG S | 2005-3711 | 1598-7876 | 67 | 6 | SCIE | CLINICAL NEUROLOGY;SURGERY | 2024 | 1.7 | 47.3 | 0 | 2025-05-07 | 0 | 0 | Craniotomy center dot Aneurysm; anterior communicating artery center dot Subarachnoid hemorrhage center dot Blister-like aneurysm | INTERNAL CAROTID-ARTERY; DE-NOVO ANEURYSM; SUBARACHNOID HEMORRHAGE; WALL | Aneurysm, anterior communicating artery; Blister-like aneurysm; Craniotomy; Subarachnoid hemorrhage | adult; angiogram negative subarachnoid hemorrhage; anterior communicating artery; anterior communicating artery aneurysm; Article; blister; blood clot; brain hemorrhage; case report; clinical article; computed tomographic angiography; computer assisted tomography; craniotomy; digital subtraction angiography; doppler sonography; echography; hemodynamics; human; male; microsuturing technique; middle aged; middle cerebral artery; subarachnoid hemorrhage; surgical technique | English | 2024 | 2024-11 | 10.3340/jkns.2024.0069 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Herding behavior and digital trading during the crisis | Digital innovation in the stock trading portal system may cause variations in herding behavior between the 2008 financial crisis and the pandemic crisis. Using the new digital technology has resulted in a rapid growth of turnover ratio and facilitated easy access to the internet trading portal systems, leading to a significant surge in trade volume. Focusing on the role of digital trading during the recent crisis, this paper proposes a new perspective on investigating herding behavior through the cross-sectional absolute deviation of returns (CSAD) model. Trade volume and its variance are crucially associated with herding behavior during a crisis. During this period, investors respond more promptly to exogenous shocks by rebalancing their portfolios due to digital innovations in the digital trading system compared to the past. This study utilizes panel fixed effects models and 2SLS models of daily panel data on Korean and China Shanghai A stock markets in Asia from January 2005 to 2021. The findings strongly support the new hypotheses, indicating that trade volume and its variance are significantly associated with herding behaviors in the pandemic crisis and that its impacts differ from those of the 2008 financial crisis in Asia. Recent digital innovations tend to have a more direct influence on herding behavior, albeit less indirectly through the surge in trade volume on the digital trading system. This study contributes to the extant literature by exploring the influence of digital innovation and digital trading on herding behavior during the recent crisis. The findings can be used to analyze herding behavior in foreign exchange, bond, and housing markets. | Kim, Heeho; Hongxia, Zhang | Kyungpook Natl Univ, Sch Econ &Trade, 80 Daehak Ro, Daegu 41566, South Korea; Shandong Normal Univ, Sch Econ, 88 East Wenhua Rd, Jinan, Shandong, Peoples R China | Kim, Heeho/AAO-8809-2021 | 36727893700; 57199714616 | kimhh@knu.ac.kr;lymyzhx1016@163.com; | JOURNAL OF ECONOMICS AND FINANCE | J ECON FINANC-US | 1055-0925 | 1938-9744 | 48 | 4 | ESCI | BUSINESS, FINANCE;ECONOMICS | 2024 | 1.5 | 47.4 | 0 | 2025-05-07 | 0 | 0 | Herding behavior; Cross-sectional absolute deviation; Pandemic crisis; Financial crisis; Digital trading | CHINESE; MARKETS | Cross-sectional absolute deviation; Digital trading; Financial crisis; Herding behavior; Pandemic crisis | English | 2024 | 2024-12 | 10.1007/s12197-024-09683-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Prenatal Diagnosis and Clinical Outcomes of Isolated Mega Cisterna Magna | Objective: The study aimed to investigate the clinical outcomes of fetuses diagnosed with isolated mega cisterna magna in utero. Methods: A multicenter retrospective cohort study was conducted across 18 university hospitals from 2010 to 2019. Cases diagnosed with isolated mega cisterna magna, defined as a cisterna magna >10 mm with a normal cerebellar vermis and no cystic dilation of the fourth ventricle, were included. Cases with other central nervous system (CNS) anomalies, extra-central nervous system anomalies, chromosomal abnormalities, or congenital infections were excluded. Maternal demographics, prenatal findings, delivery outcomes, and postnatal outcomes were analyzed. Results: The mean gestational age at initial diagnosis was 28.6 +/- 3.9 weeks, and the mean anteroposterior diameter of the cisterna magna was 12.5 +/- 3.2 mm. Of the 71 cases initially assessed, 48 (67.6%) showed self-regression in utero. Postnatally, 13 cases (18.3%) had persistent isolated mega cisterna magna, whereas 10 cases (14.1%) were diagnosed with other central nervous system anomalies. Among the persistent isolated mega cisterna magna cases, one child exhibited delayed neurodevelopment. There was a higher incidence of isolated mega cisterna magna in male fetuses, which exhibited a significantly larger mean cisterna magna diameter compared with female fetuses (P = .045). Conclusion: Male fetuses exhibited a higher incidence of isolated mega cisterna magna compared with female fetuses and had larger anteroposterior diameters of the cisterna magna. The study demonstrated favorable neurodevelopmental outcomes associated with isolated mega cisterna magna, with self-regression observed in two-thirds of the cases. However, consecutive prenatal and postnatal evaluations for additional central nervous system or extra-central nervous system malformations need to be performed, considering the differences between prenatal and postnatal diagnoses. | Kim, Oyoung; Hong, Subeen; Jung, Young Mi; Seol, Hyun-Joo; Na, Sunghun; Bae, Jin Gon; Ahn, Ki Hoon; Lee, Mi-Young; Kwon, Ha Yan; Sung, Ji-Hee; Choi, Soo Ran; Kim, Seung Cheol; Lee, Kyung A.; Kim, Hee Sun; Kim, Mi Ju; Song, Ji Eun; Hwang, Han Sung; Won, Hye-Sung; Jun, Jong Kwan; Ko, Hyun Sun | Catholic Univ Korea, Yeouido St Marys Hosp, Coll Med, Dept Obstet & Gynecol, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Obstet & Gynecol, 222,Banpo Daero, Seoul 06591, South Korea; Seoul Natl Univ Hosp, Dept Obstet & Gynecol, Seoul, South Korea; Korea Univ, Dept Obstet & Gynecol, Coll Med, Seoul, South Korea; Kyung Hee Univ, Dept Obstet & Gynecol, Sch Med, Seoul, South Korea; Kangwon Natl Univ, Kangwon Natl Univ Hosp, Sch Med, Dept Obstet & Gynecol, Chunchon, South Korea; Keimyung Univ, Coll Med, Dept Obstet & Gynecol, Daegu, South Korea; Univ Ulsan, Asan Med Ctr, Dept Obstet & Gynecol, Coll Med, Seoul, South Korea; Yonsei Univ Hlth Syst, Severance Hosp, Dept Obstet & Gynecol, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Obstet & Gynecol, Sch Med, Seoul, South Korea; Inha Univ, Dept Obstet & Gynecol, Coll Med, Incheon, South Korea; Pusan Natl Univ, Biomed Res Inst, Dept Obstet & Gynecol, Coll Med, Busan, South Korea; Ewha Womans Univ, Coll Med, Dept Obstet & Gynecol, Seoul, South Korea; Inje Univ, Ilsan Paik Hosp, Dept Obstet & Gynecol, Coll Med, Goyang, South Korea; Kyungpook Natl Univ, Sch Med, Dept Obstet & Gynecol, Daegu, South Korea; Hallym Univ, Coll Med, Kangnam Sacred Heart Hosp, Dept Obstet & Gynecol,Med Ctr, Seoul, South Korea; Konkuk Univ, Sch Med, Dept Obstet & Gynecol, Div Maternal & Fetal Med,Med Ctr, Seoul, South Korea | Kim, Mi Ju/HGU-8470-2022; JUNG, YOUNGMI/H-6360-2013; Jun, Jong/D-5776-2012; Song, Jie/GLR-2301-2022 | 57210171579; 57208189052; 57204270409; 15924081200; 55489142900; 57215844401; 26031248300; 57202097314; 36865684900; 56347330000; 55756824400; 57188949183; 57203464136; 57195511578; 55908927600; 59379764500; 17345595900; 7006567796; 7202753014; 37026301100 | jhs0927@snu.ac.kr;mongkoko@catholic.ac.kr; | JOURNAL OF CHILD NEUROLOGY | J CHILD NEUROL | 0883-0738 | 1708-8283 | 39 | 13-14 | SCIE | CLINICAL NEUROLOGY;PEDIATRICS | 2024 | 1.6 | 47.4 | 0 | 2025-05-07 | 0 | 0 | Congenital Abnormality; Mega Cisterna Magna; Prenatal Ultrasound | POSTERIOR-FOSSA; DEVELOPMENTAL DELAY; FETAL; ANOMALIES; GROWTH | Congenital Abnormality; Mega Cisterna Magna; Prenatal Ultrasound | Adult; Cisterna Magna; Cohort Studies; Female; Gestational Age; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Diagnosis; Retrospective Studies; Ultrasonography, Prenatal; adult; Apgar score; Article; body mass; brain fourth ventricle; brain ventricle dilatation; central nervous system; cisterna magna; clinical outcome; cohort analysis; congenital malformation; demographics; echography; female; fetus; fetus karyotyping; follow up; gestational age; hospitalization; human; isolated mega cisterna magna; major clinical study; male; multicenter study; newborn intensive care; nuclear magnetic resonance imaging; pregnancy outcome; prenatal diagnosis; retrospective study; clinical trial; diagnostic imaging; fetus echography; newborn; pregnancy; prenatal diagnosis; procedures | English | 2024 | 2024-11 | 10.1177/08830738241282037 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Excess Deaths in Korea During the COVID-19 Pandemic: 2020-2022 | Objectives: Excess deaths, an indicator that compares total mortality rates before and during a pandemic, offer a comprehensive view of the pandemic's impact. However, discrepancies may arise from variations in estimating expected deaths. This study aims to compare excess deaths in Korea during the coronavirus disease 2019 pandemic using 3 methods and to analyze patterns using the most appropriate method. Methods: Expected deaths from 2020 to 2022 were estimated using mortality data from 2015-2019 as reference years. This estimation employed 3 approaches: (1) simple average, (2) age-adjusted average, and (3) age-adjusted linear regression. Excess deaths by age, gender, and cause of death were also presented. Results: The number of excess deaths varied depending on the estimation method used, reaching its highest point with the simple average and its lowest with the age-adjusted average. Age-adjusted linear regression, which accounts for both the aging population and declining mortality rates, was considered most appropriate. Using this model, excess deaths were estimated at 0.3% for 2020, 4.0% for 2021, and 20.7% for 2022. Excess deaths surged among individuals in their 20s throughout the pandemic, largely attributed to a rise in self-harm and suicide. Additionally, the results indicated sharp increases in deaths associated with "endocrine, nutritional, and metabolic diseases" and "symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified." Conclusions: Substantial variations in excess deaths were evident based on estimation method, with a notable increase in 2022. The heightened excess deaths among young adults and specific causes underscore key considerations for future pandemic responses. | Im, So-Jin; Shin, Ji-Yeon; Lee, Duk-Hee | Daegu City Hall, Dept Hlth & Med Policy, Daegu, South Korea; Kyungpook Natl Univ, Grad Sch, Dept Publ Hlth, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Prevent Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea | 59357966000; 55567961600; 57211851121 | lee_dh@knu.ac.kr; | JOURNAL OF PREVENTIVE MEDICINE & PUBLIC HEALTH | J PREV MED PUBLIC HL | 1975-8375 | 2233-4521 | 57 | 5 | ESCI | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2024 | 2.1 | 47.6 | 0 | 2025-05-07 | 0 | 0 | COVID-19; Excess mortality; Mortality; Pandemics; SARS-CoV-2; Suicide | COVID-19; Excess mortality; Mortality; Pandemics; SARS-CoV-2; Suicide | Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Cause of Death; Child; Child, Preschool; COVID-19; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Mortality; Pandemics; Republic of Korea; SARS-CoV-2; Young Adult; adolescent; adult; aged; Article; automutilation; cause of death; child; clinical feature; comparative study; coronavirus disease 2019; endocrine disease; excess mortality; female; gender; groups by age; human; infant; Korea; Korean (people); laboratory test; linear regression analysis; major clinical study; male; metabolic disorder; middle aged; mortality rate; newborn; nutritional disorder; pandemic; suicide; very elderly; age; coronavirus disease 2019; epidemiology; mortality; pandemic; preschool child; Severe acute respiratory syndrome coronavirus 2; South Korea; young adult | English | 2024 | 2024-09 | 10.3961/jpmph.24.254 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Independent isomeric yield ratios of fission products in the epi-cadmium neutron-induced fission of ²⁴⁵Cm | Independent isomeric yield ratios (IR) of Sb-128,Sb-130,Sb-132, Te-131,Te-133, I-132,I-134, Xe-135 and Cs-138 in the epi-cadmium neutron-induced fission of Cm-245 have been measured for the first time by using an off-line gamma-ray spectrometric technique. The average energy of the epi-cadmium neutron spectrum () is 1.9 MeV. From the IR values, root mean square fragment angular momenta (J(RMS)) were deduced by using the spin dependent statistical model analysis. The IR and J(RMS) values of the fission products from the present work were compared with the literature data in the thermal neutron-induced fission of Cm-245 to examine the role of excitation energy. Effect of nuclear structure on J (RMS) value was also examined. | Naik, Haladhara; Singh, Ram Janam; Dange, Srikant Pandurang; Jang, Wooyoung | Bhabha Atom Res Ctr, Radiochem Div, Mumbai 400085, India; Kyungpook Natl Univ, Dept Phys, Daegu 54150, South Korea | 7005890232; 24322531600; 6602557752; 59777352500 | naikhbarc@yahoo.com; | RADIOCHIMICA ACTA | RADIOCHIM ACTA | 0033-8230 | 2193-3405 | 112 | 11 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR;NUCLEAR SCIENCE & TECHNOLOGY | 2024 | 1.7 | 47.6 | 0 | 2025-05-07 | 0 | 0 | Cm-245(n, f) reaction; <E-n>=1.9 MeV; independent isomeric yield ratios; off-line gamma-ray spectrometry; fragment angular momenta; effects of excitation energy and nuclear structure | FRAGMENT ANGULAR-MOMENTUM; ENERGY FISSION; U-233; MODEL; ISOTOPES; PU-239 | <E <sub>n </sub>> = 1.9 MeV; <sup>245</sup>Cm(n, f) reaction; effects of excitation energy and nuclear structure; fragment angular momenta; independent isomeric yield ratios; off-line γ-ray spectrometry | English | 2024 | 2024-11-26 | 10.1515/ract-2024-0287 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Modulation of synaptic transmission through O-GlcNAcylation | O-GlcNAcylation is a posttranslational modification where N-acetylglucosamine (O-GlcNAc) is attached and detached from a serine/threonine position by two enzymes: O-GlcNAc transferase and O-GlcNAcase. In addition to roles in diabetes and cancer, recent pharmacological and genetic studies have revealed that O-GlcNAcylation is involved in neuronal function, specifically synaptic transmission. Global alteration of the O-GlcNAc level does not affect basal synaptic transmission while the effect on synaptic plasticity is unclear. Although synaptic proteins that are O-GlcNAcylated are gradually being discovered, the mechanism of how O-GlcNAcylated synaptic protein modulate synaptic transmission has only been reported on CREB, synapsin, and GluA2 subunit of AMPAR. Future research enabling the manipulation of O-GlcNAcylation in individual synaptic proteins should reveal hidden aspects of O-GlcNAcylated synaptic proteins as modulators of synaptic transmission. | Han, Seunghyo; Kim, Jun-Nyeong; Park, Chan Ho; Byun, Jin-Seok; Kim, Do-Yeon; Ko, Hyoung-Gon | Kyungpook Natl Univ, Brain Sci & Engn Inst, Sch Dent, Dept Anat & Neurobiol, 2177 Dalgubeol Daero, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Dent Biomat, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Oral Med, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Pharmacol, Daegu 41940, South Korea | Kim, Do-Yeon/AET-3021-2022; Ko, Hyoung-Gon/KQU-8680-2024; Park, Chan/AAH-8055-2020 | 58751707300; 58790999200; 55728043300; 55430621800; 57203012542; 14522654800 | hgko@knu.ac.kr; | MOLECULAR BRAIN | MOL BRAIN | 1756-6606 | 17 | 1 | SCIE | NEUROSCIENCES | 2024 | 2.9 | 47.6 | 0.19 | 2025-05-07 | 1 | 1 | O-GlcNAcylation; O-GlcNAc transferase; O-GlcNAcase; Synaptic transmission; Synaptic plasticity | GLCNAC-MODIFIED PROTEINS; IDENTIFICATION; GLYCOSYLATION; LOCALIZATION; TRANSFERASE; CREB | O-GlcNAc transferase; O-GlcNAcase; O-GlcNAcylation; Synaptic plasticity; Synaptic transmission | Diabetes Mellitus; Humans; Neurons; Protein Processing, Post-Translational; Proteins; Synaptic Transmission; acetylglucosaminidase; ankyrin G; bassoon; cell protein; n acetylglucosamine; n acetylglucosamine transferase; piccolo; protein GKAP; shank2; synapsin I; synaptopodin; transferase; unclassified drug; protein; endocytosis; hippocampal CA1 region; hippocampal CA3 region; internalization (cell); nerve cell excitability; nerve cell plasticity; neuromodulation; nonhuman; O GlcNAcylation; protein expression; protein function; protein localization; protein processing; Review; synapse vesicle; synaptic transmission; diabetes mellitus; human; nerve cell; physiology; synaptic transmission | English | 2024 | 2024-01-02 | 10.1186/s13041-023-01072-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The overexpression of DSP1 in neurons induces neuronal dysfunction and neurodegeneration phenotypes in Drosophila | Dorsal switch protein 1(DSP1), a mammalian homolog of HMGB1, is firstly identified as a dorsal co-repressor in 1994. DSP1 contains HMG-box domain and functions as a transcriptional regulator in Drosophila melanogaster. It plays a crucial role in embryonic development, particularly in dorsal-ventral patterning during early embryogenesis, through the regulation of gene expression. Moreover, DSP1 is implicated in various cellular processes, including cell fate determination and tissue differentiation, which are essential for embryonic development. While the function of DSP1 in embryonic development has been relatively well-studied, its role in the adult Drosophila brain remains less understood. In this study, we investigated the role of DSP1 in the brain by using neuronal-specific DSP1 overexpression flies. We observed that climbing ability and life span are decreased in DSP1-overexpressed flies. Furthermore, these flies demonstrated neuromuscular junction (NMJ) defect, reduced eye size and a decrease in tyrosine hydroxylase (TH)-positive neurons, indicating neuronal toxicity induced by DSP1 overexpression. Our data suggest that DSP1 overexpression leads to neuronal dysfunction and toxicity, positioning DSP1 as a potential therapeutic target for neurodegenerative diseases. | Baek, Si-Eun; Kwon, Younghwi; Yoon, Jong-Won; Kim, Hyo-Sung; Yang, Jae-Yoon; Lee, Dong-Seok; Yeom, Eunbyul | Kyungpook Natl Univ, Coll Nat Sci, Sch Life Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Life Sci, FOUR KNU Creat BioRes Grp BK21, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Sch Life Sci, KNU G LAMP Project Grp,KNU Inst Basic Sci, Daegu 41566, South Korea | Yang, Jaeyoon/LYP-2093-2024 | 58954689000; 57194168806; 58955243000; 57226241873; 58954317200; 57210068061; 56058004100 | lee1@knu.ac.kr;yeb@knu.ac.kr; | MOLECULAR BRAIN | MOL BRAIN | 1756-6606 | 17 | 1 | SCIE | NEUROSCIENCES | 2024 | 2.9 | 47.6 | 0.45 | 2025-05-07 | 1 | 1 | Neurodegeneration; DSP1; HMGB1; Neuromuscular junction; Drosophila | DNA-BINDING; PROTEIN | Drosophila; DSP1; HMGB1; Neurodegeneration; Neuromuscular junction | Animals; Drosophila melanogaster; Drosophila Proteins; Eye; Longevity; Nerve Degeneration; Neuromuscular Junction; Neurons; Phenotype; Transcription Factors; Tyrosine 3-Monooxygenase; dorsal switch protein 1; high mobility group B1 protein; tyrosine 3 monooxygenase; unclassified drug; Drosophila protein; transcription factor; tyrosine 3 monooxygenase; adult; animal cell; animal experiment; animal model; animal tissue; Article; controlled study; degenerative disease; Drosophila melanogaster; embryo; female; gene expression; lifespan; male; nerve cell; nerve degeneration; neuromuscular junction; neurotoxicity; nonhuman; pathophysiology; phenotype; animal; Drosophila melanogaster; eye; genetics; longevity; metabolism; nerve degeneration; neuromuscular junction; pathology | English | 2024 | 2024-07-13 | 10.1186/s13041-024-01117-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Assessing the restorative effects of observing a video of dog play in urban dog parks using EEG | Contact with nature is restorative and leads to health benefits via nearby nature such as gardens, natural scenes, and interactions with companion animals. Although the recovery effect of natural environments is well known, few studies examine the restorative value of watching animals in urban park settings such as off-leash dog areas in urban parks. This study aims to investigate the restorative effect of observing dog play in urban dog parks by measuring brain activity, emotional state, and perceived restorativeness. Brain activity and psychological responses were measured by electroencephalography (EEG) and the perceived restorativeness scale (PRS)/profile of mood states, respectively. The EEG results demonstrated that the dog play video produced significantly lower alpha and higher beta power spectra, which suggested that the subjects were attentive and focused by accepting the scene as an interesting stimulus. Among the subscales of the PRS, fascination plays an important role in the restorative effects of watching dog play. The subjects felt more lively, cheerful, and interested than they did when watching the city and natural view videos. Thus, the perceived restorative values of watching dog play video in dog parks are comparable to those of natural park video environments. Moreover, dog parks exerted positive effects regardless of dog ownership status by improving mood and enhancing restorative experience. Opportunities for watching dog play in safe places around dog parks through considerable park planning would extend the health benefits of dog parks to non-dog owners and improve negative attitudes toward dog parks. | Lee, Hyung-Sook; Lee, Jeong-Yeon | Kyungpook Natl Univ, Dept Landscape Architecture, Daegu, South Korea | Jeong Yeon, Lee/NFT-1014-2025; Lee, Hyung/HGB-2587-2022 | 59814620800; 57449281300 | jyeony@knu.ac.kr; | HUMAN-ANIMAL INTERACTIONS | HUM-ANIM INTERACT | 2957-9538 | 12 | 1 | ESCI | VETERINARY SCIENCES | 2024 | 1.3 | 47.9 | 0 | 2025-05-07 | 0 | 0 | dog park; dog play scene; electroencephalography; perceived restorativeness scale; restorative value | STRESS; BIODIVERSITY; TELEVISION; PERCEPTION; COMPONENTS; PREFERENCE; RESPONSES; EXPOSURE; BENEFITS; CATS | dog park; dog play scene; electroencephalography; perceived restorativeness scale; restorative value | English | 2024 | 2024-01 | 10.1079/hai.2024.0037 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Can neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios be used as markers for hypercortisolism in dogs? | Changes in neutrophil-to-lymphocite ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been identified in dogs with hypercortisolism (HC), but, no studies have investigated the changes in these inflammatory biomarkers as cost-effective and available parameters for the diagnosis and management of HC. This study was performed to evaluate whether NLR and PLR could be used as biomarkers for the diagnosis and treatment response in dogs with HC. This retrospective study included 67 dogs with HC, 58 dogs with non-adrenal illness (NAI), and 39 healthy dogs. NLR and PLR were compared among the three groups. Cut-off values of NLR and PLR for HC screening and percent change in biomarkers for assessing treatment response were evaluated. In addition, the NLR and PLR were compared before and after trilostane treatment. NLR and PLR were significantly higher in the HC group than in the NAI and healthy groups. The NLR cut-off value of 4.227 had a sensitivity of 67.16% and specificity of 65.52%, and the PLR cut-off value of 285.0 had a sensitivity of 56.72% and specificity of 70.69% for differentiating between dogs with HC and those with NAI, respectively. Furthermore, a significant decline in NLR was observed after treatment in the well-controlled HC group. The cutoff value of percent change in NLR to identify well-controlled HC was -7.570%; sensitivity and specificity were 100% and 63.64%, respectively. Therefore, NLR and PLR might be used cautiously as supportive biomarkers for HC diagnosis, and NLR could be a potential monitoring tool in assessing the treatment response of HC in dogs. | Yun, Sumin; Yun, Taesik; Cha, Sijin; Oh, Jimin; Lee, Dohee; Koo, Yoonhoi; Chae, Yeon; Yang, Mhan-Pyo; Kang, Byeong-Teck; Kim, Hakhyun | Chungbuk Natl Univ, Coll Vet Med, Lab Vet Internal Med, Cheongju 28644, Chungbuk, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea | 57215859912; 57209458067; 58564731200; 57259447100; 57226189094; 57220050745; 57215577118; 7404927049; 8858992400; 57192503045 | kimh@chungbuk.ac.kr; | TOPICS IN COMPANION ANIMAL MEDICINE | TOP COMPANION ANIM M | 1938-9736 | 1946-9837 | 61 | SCIE | VETERINARY SCIENCES | 2024 | 1.3 | 47.9 | 3.93 | 2025-05-07 | 3 | 3 | Biomarker; Canine; Hypercortisolism; Trilostane | CUSHINGS-DISEASE; HYPERADRENOCORTICISM; STRESS; DIAGNOSIS; PLR; NLR | Biomarker; Canine; Hypercortisolism; Trilostane | Animals; Biomarkers; Blood Platelets; Cushing Syndrome; Dihydrotestosterone; Dog Diseases; Dogs; Female; Lymphocytes; Male; Neutrophils; Platelet Count; Retrospective Studies; Sensitivity and Specificity; alanine aminotransferase; alkaline phosphatase; biological marker; corticotropin; dexamethasone; glucocorticoid; glucose; hydrocortisone; luteinizing hormone; trilostane; vetoryl; androstanolone; biological marker; trilostane; abdominal radiography; adrenal gland; alopecia; area under the curve; Article; blood analysis; body weight; chemiluminescence immunoassay; controlled study; corticotropin test; Cushing disease; diagnostic test accuracy study; dog disease; echography; female; hypercortisolism; hyperglycemia; hypertriglyceridemia; iron binding capacity; lymphocyte count; male; neutrophil count; neutrophil lymphocyte ratio; nonhuman; platelet count; platelet lymphocyte ratio; polydipsia; polyuria; receiver operating characteristic; retrospective study; sensitivity and specificity; teaching hospital; treatment response; urinalysis; animal; blood; Cushing syndrome; diagnosis; dog; lymphocyte; neutrophil; thrombocyte; veterinary medicine | English | 2024 | 2024 (JUL-AUG) | 10.1016/j.tcam.2024.100890 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Expression of sphingosine-1-phosphate receptor 1 in neuroinflammation of canine brains | Sphingosine-1-phosphate (S1P) is a signaling lipid mediator that is involved in multiple biological processes. The S1P/S1P receptor (S1PR) signaling pathway has an important role in the central nervous system. It contributes to physiologic cellular homeostasis and is also associated with neuroinflammation. Therefore, this study was performed to evaluate the expression of S1PR in dogs with meningoencephalitis of unknown etiology (MUE) and experimental autoimmune encephalomyelitis (EAE). The analysis used 12 brain samples from three neurologically normal dogs, seven dogs with MUE, and two canine EAE models. Anti-S1PR1 antibody was used for immunohistochemistry. In normal brain tissues, S1PR1s were expressed on neurons, astrocytes, oligodendrocytes, and endothelial cells. In MUE and EAE lesions, there was positive staining of S1PR1 on leukocytes. Furthermore, the expression of S1PR1 on neurons, astrocytes, oligodendrocytes, and endothelial cells was upregulated compared to normal brains. This study shows that S1PR1s are expressed in normal brain tissues and leukocytes in inflammatory lesions, and demonstrates the upregulation of S1PR1 expression on nervous system cells in inflammatory lesions of MUE and EAE. These findings indicate that S1P/S1PR signaling pathway might involve physiologic homeostasis and neuroinflammation and represent potential targets for S1PR modulators to treat MUE. | Yun, Taesik; Kim, Sanggu; Koo, Yoonhoi; Chae, Yeon; Lee, Dohee; Kim, Hakhyun; Yang, Mhan-Pyo; Kang, Byeong-Teck; Kim, Soochong | Chungbuk Natl Univ, Coll Vet Med, Lab Vet Internal Med, Cheongju 28644, Chungbuk, South Korea; Chungbuk Natl Univ, Coll Vet Med, Lab Vet Pathol, Cheongju 28644, Chungbuk, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea | 57209458067; 57220812847; 57220050745; 57215577118; 57226189094; 57192503045; 7404927049; 8858992400; 7601600702 | kangbt@chungbuk.ac.kr;skim0026@chungbuk.ac.kr; | TOPICS IN COMPANION ANIMAL MEDICINE | TOP COMPANION ANIM M | 1938-9736 | 1946-9837 | 60 | SCIE | VETERINARY SCIENCES | 2024 | 1.3 | 47.9 | 1.31 | 2025-05-07 | 1 | 1 | Dog; EAE; Experimental autoimmune encephalomyelitis; Meningoencephalitis of unknown etiology; MUE; S1PR1 | ORAL FINGOLIMOD; NECROTIZING MENINGOENCEPHALITIS; SPHINGOLIPID METABOLISM; LYMPHOCYTE EGRESS; FTY720; CELLS | Dog; EAE; Experimental autoimmune encephalomyelitis; Meningoencephalitis of unknown etiology; MUE; S1PR1 | Animals; Astrocytes; Brain; Dog Diseases; Dogs; Encephalomyelitis, Autoimmune, Experimental; Female; Male; Meningoencephalitis; Neuroinflammatory Diseases; Sphingosine-1-Phosphate Receptors; sphingosine 1 phosphate; sphingosine 1 phosphate receptor; sphingosine 1 phosphate receptor; animal tissue; Article; astrocyte; autoimmune encephalomyelitis; brain; brain stem; brain tissue; cell proliferation; central nervous system; central nervous system infection; cerebellum; controlled study; dilated cardiomyopathy; dog; encephalomyelitis; endothelium cell; experimental autoimmune encephalomyelitis; female; frontal lobe; granulomatous meningoencephalitis; homeostasis; hypertrophy; immune response; immunohistochemistry; immunoreactivity; inflammation; leukocyte; male; meningoencephalitis; mitral valve disease; nerve cell; nervous system inflammation; nonhuman; oligodendroglia; parietal lobe; physiology; protein expression; signal transduction; upregulation; animal; dog disease; experimental autoimmune encephalomyelitis; metabolism; nervous system inflammation; veterinary medicine | English | 2024 | 2024 (MAY-JUN) | 10.1016/j.tcam.2024.100847 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Who Makes Popular Content? Information Cues from Content Creators for Users' game Choice: Focusing on User-Created Content Platform "Roblox" | User-generated game platforms have emerged as a channel fostering creative activities in online communities. Therefore, this study reveals users' decision making at UGG platform such as Roblox, where millions of users contribute to game creation and play the game. In particular, teenagers, who are digital natives and known as Generation Z, select a game from various UGGs on Roblox. Thus, this study focuses on how game creator information in personal profile plays a significant role in determining digital natives' choice of UGG. Drawing the signaling theory, this research focus on creators' abilities and popularities as indicators for UGG choices. We collect a total of 1,301 fighting games from Roblox and game creator information. To address endogeneity, a twostage least squares(2SLS) analysis was conducted using instrumental variables. The results show that the number of limited items and followers achieved by the creator positively affect game popularity. | Kang, Young-joo; Lee, Ui-jun; Lee, Saerom | Seoul Natl Univ, Coll Business Adm, 1 Gwanak Ro, Seoul 151742, South Korea; Kyungpook Natl Univ, Sch Elect Engn, 80 Daehakro, Bukgu 41566, Daegu, South Korea | 59012240800; 59011756400; 56023428700 | sullng102102@gmail.com;leeeuijun0604@gmail.com;saeromlee@knu.ac.kr; | ENTERTAINMENT COMPUTING | ENTERTAIN COMPUT | 1875-9521 | 1875-953X | 50 | SCIE | COMPUTER SCIENCE, CYBERNETICS;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;COMPUTER SCIENCE, SOFTWARE ENGINEERING | 2024 | 2.4 | 48.0 | 0 | 2025-05-07 | 1 | 2 | User-generated game; Modding behavior; Signaling theory; Self-disclosure; Roblox; generation Z | GENERATED CONTENT; MEDIATING ROLE; QUALITY; YOUTUBE; ENGAGEMENT; NETWORK; MODELS | generation Z; Modding behavior; Roblox; Self-disclosure; Signaling theory; User-generated game | User profile; Content creators; Digital natives; Generation Z; Information cues; Modding behavior; Roblox; Self-disclosure; Signaling theory; User-generated; User-generated game; Decision making | English | 2024 | 2024-05 | 10.1016/j.entcom.2024.100697 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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