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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Mid-term to Long-term Follow-up Results of Reconstruction for Thumb Radial Polydactyly | Background: Preaxial or radial polydactyly is one of the most common hand congenital anomalies in newborns. Contemporary reconstruction methods include ligament reconstruction, excision of the polydactylous thumb, osteotomy, and other surgical techniques according to the type of polydactyly. The purpose of this study was to report mid-term to long-term reconstruction results for thumb (radial) polydactyly. Methods: We retrospectively reviewed the medical records of patients who underwent reconstruction surgery for preaxial polydactyly. Clinical outcomes, including the range of motion (ROM), pain, and complications, were evaluated. We assessed the final radiographs of the reconstructed thumb to identify the potential development of arthritis or other remaining deformities. After excluding cases without a simple radiograph and cases with a short follow-up period of fewer than 5 years, 26 thumbs were included. The surgical technique followed including excision of polydactylout thumb was tailored to the type of polydactyly. If the nail size of the thumbs was similar, the Bilhaut-Cloquet method was preferred. Results: The mean age of the patients at the surgery and final follow-up was 14.9 months (range: 8 to 30 mo) and 11.9 years (range: 5.8 to 19.3 y), respectively. The mean follow-up was 128.8 months years (range: 60 to 219 mo), and the mean ROM of the thumb was 32.7 and 57.5 degrees in the distal interphalangeal joint (DIP) and metacarpophalangeal (MP) joint, respectively. Ulnar or radial side instability was prominent in 7 patients in the involved joints (26.9%). One patient underwent interphalangeal (IP) fusion for extension lag with pain. The radiologic evaluation revealed that 2 patients developed radiographic evidence of IP joint arthritis (7.7%). Radial deviation of the MP or IP joint existed in 13 cases (range: 5 to 40 degrees) (50.0%), and ulnar deviation of the MP or IP joint existed in 2 cases (range: 19 to 20 degrees) (7.7%). Conclusions: In mid-term to long-term experience, sequelae such as joint instability, joint stiffness, and remaining deformity cannot be neglected. An unstable MP joint may result if the DIP joint remains stiff or has a lower ROM. | Lee, Hyun-Joo; Lee, Kang-San; Chung, Seung-Ho; Kim, Hee-June; Park, Kyeong-Hyeon; Kim, Poong-Taek; Park, Sook-Hyun | Kyungpook Natl Univ, Dept Orthopaed Surg, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Pediat, Sch Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Orthopaed Surg, Daegu, South Korea | Park, KyeongHyeon/KEH-4919-2024 | 58838750100; 58967020700; 57221219695; 36463735200; 56969984400; 7402334714; 57194595004 | lidmania@daum.net; | JOURNAL OF PEDIATRIC ORTHOPAEDICS | J PEDIATR ORTHOPED | 0271-6798 | 1539-2570 | 42 | 8 | SCIE | ORTHOPEDICS;PEDIATRICS | 2022 | 1.7 | 64.5 | 1.07 | 2025-06-25 | 4 | 6 | thumb; polydactyly; mid to long term; results | HYPERMOBILITY; FUSION | mid to long term; polydactyly; results; thumb | Arthritis; Child, Preschool; Follow-Up Studies; Humans; Infant; Infant, Newborn; Joint Instability; Pain; Polydactyly; Range of Motion, Articular; Retrospective Studies; Thumb; adolescent; adult; arthritis; arthrodesis; Article; Bilhaut Cloquet method; child; clinical outcome; cohort analysis; disease course; distal interphalangeal joint; follow up; groups by age; hand radiography; human; interphalangeal joint; joint instability; joint stiffness; major clinical study; male; medical record review; metacarpophalangeal joint; nail; pain; postoperative complication; preaxial polydactyly; range of motion; retrospective study; thumb radial polydactyly; thumb reconstruction; arthritis; follow up; infant; joint characteristics and functions; joint instability; newborn; polydactyly; preschool child; thumb | English | 2022 | 2022-09 | 10.1097/bpo.0000000000002195 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Peri-implant atypical femoral fracture after nail or plate osteosynthesis | Background: A lack of scientific information regarding the risk factors and diagnosis of peri-implant atypical femoral fracture (PI-AFF) exists. We report a case series of developed PI-AFF with a nail or plate construct wherein prior femoral fractures were already healed after osteosynthesis. This study aimed to identify the cause and risk factors of PI-AFF and to devise a preventive method based on this. Methods: We identified 11 PI-AFFs displaying features of AFFs. All patients were ambulant females (mean age, 74.9 years). The mean T-score of the femur measured by DEXA (Dual Energy X-ray Absorptiometry) scan was 3.5. Osteosynthesis was performed with a plate and an intramedullary nail in six and five patients, respectively. Possible risk factors were investigated, including the used implant, the medication of bisphosphonate, the characteristics of previous fracture (AFF or non-AFF), and the co-existence of AFF on the contralateral side. Results: The PI-AFFs developed at an average of 6.6 years from the time of prior fracture. All fractures were located at the screw through the plate or nail. Regarding anatomic locations, seven and four fractures were at the subtrochanteric area and diaphysis, respectively. Diaphyseal PI-AFFs occurred in plating cases, all of which were associated with excessive femoral bowing. Subtrochanteric PI-AFFs included all five patients with nail fixation, which occurred near a proximal interlocking screw. Six of the 11 patients were on bisphosphonate treatment before or at the time of fracture. The duration of bisphosphonate treatment was 6 years on average. Concerning the previous femoral fractures, seven and four patients were AFF and non-AFF, respectively. Considering the pathology on the contralateral leg, eight had suffered diaphyseal AFF. Four patients were treated nonoperatively. Seven patients needed an operation; 6 of them healed after reconstruction nailing, and one needed hip arthroplasty because of the associated displaced femoral neck fracture. Conclusions: PI-AFFs may develop through the screw hole at the subtrochanteric or diaphyseal area due to femoral fragility and stress riser effect of the implant. An improved osteosynthesis strategy may be necessary to avoid PI-AFFs when fixing osteoporotic femoral fractures. (C) 2021 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved. | Kim, Joon-Woo; Oh, Chang-Wug; Park, Kyeong-Hyeon; Oh, Jong-Keon; Yoon, Yong-Cheol; Kim, June-Kyu | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthopaed Surg, 130 Dongduk Ro,Jung Gu, Daegu 41944, South Korea; Korea Univ, Dept Orthopaed Surg, Guro Hosp, 148 Gurodong Ro,Guro Gu, Seoul 08308, South Korea; Gachon Univ, Orthoped Trauma Div, Trauma Ctr, Coll Med, 21Namdong Daero 774 Beon Gil,Namdong Gu, Incheon 21565, South Korea | Oh, Chang-Wug/AAO-4602-2021; Park, KyeongHyeon/KEH-4919-2024; Yong-Cheol, Yoon/HPD-8077-2023 | 22951329000; 22135834200; 56969984400; 7402155046; 37082544400; 57849277400 | cwoh@knu.ac.kr; | JOURNAL OF ORTHOPAEDIC SCIENCE | J ORTHOP SCI | 0949-2658 | 1436-2023 | 27 | 4 | SCIE | ORTHOPEDICS | 2022 | 1.7 | 64.5 | 0.91 | 2025-06-25 | 3 | 5 | LONG-TERM BISPHOSPHONATES; INSUFFICIENCY FRACTURES; LOCATION; BONE | Aged; Diphosphonates; Female; Femoral Fractures; Femur; Humans; Osteoporotic Fractures; Periprosthetic Fractures; Radiography; alendronic acid; calcium; parathyroid hormone[1-34]; risedronic acid; vitamin D; bisphosphonic acid derivative; adult; aged; Article; bipolar hemiarthroplasty; bone bowing; bone scintiscanning; clinical article; conservative treatment; disease association; distal femur fracture; drug withdrawal; dual energy X ray absorptiometry; female; femoral neck fracture; femur diaphysis; femur fracture; femur subtrochanteric fracture; fracture healing; fragility fracture; hip arthroplasty; hip radiography; human; incidence; middle aged; peri-implant fracture; periprosthetic fracture; plate fixation; reoperation; risk factor; total knee arthroplasty; very elderly; diagnostic imaging; femur; femur fracture; fragility fracture; pathology; periprosthetic fracture; radiography | English | 2022 | 2022-07 | 10.1016/j.jos.2021.04.008 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | The velvet-activated putative C6 transcription factor VadZ regulates development and sterigmatocystin production in Aspergillus nidulans | The NF-kappa B-type VosAeVelB velvet complex acts as a global regulator governing development and metabolism in fungi. One of the VosA-VelB-activated developmental (VAD) genes called vadZ is predicted to encode a 557-amino acid protein containing a highly conserved GAL4-type Zn(II)(2)Cys(6) (or C-6 zinc) binuclear cluster DNA-binding domain in Aspergillus nidulans. In this report, we characterize the function of the vadZ gene in controlling development and sterigmatocystin (ST) production in A. nidulans. To verify VosA-VelB mediated activation of vadZ, we checked relative mRNA levels of vadZ in wild-type (WT), Delta vosA, and Delta velB mutant strains during vegetative, asexual, and sexual development phases. At the beginning of asexual development, the absence of vosA led to a 66.2-fold lowered vadZ mRNA levels, whereas Delta velB resulted in a 3.6-fold decrease in vadZ mRNA levels. The deletion of vadZ resulted in significantly restricted colony growth coupled with reduced asexual development, but increased formation of sexual fruiting bodies called cleistothecia. In addition, nullifying vadZ caused elevated mRNA levels of the two key sexual developmental activators esdC and nsdD throughout the lifecycle. Moreover, the Delta vadZ mutant showed elevated production of ST and enhanced mRNA levels of ST biosynthetic genes. In summary, the putative C-6 transcription factor VadZ promotes asexual development and suppresses the sexual development and the ST production in A. | Zhao, Yanxia; Lee, Mi-Kyung; Lim, Jieyin; Moon, Heungyun; Park, Hee-Soo; Zheng, Weifa; Yu, Jae-Hyuk | Jiangsu Normal Univ, Dept Life Sci, Xuzhou 221116, Jiangsu, Peoples R China; Korea Res Inst Biosci & Biotechnol, Biol Resource Ctr, Jeongeup 56212, South Korea; Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 USA; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Konkuk Univ, Dept Syst Biotechnol, Seoul 05029, South Korea | Yu, Jae-Hyuk/A-2343-2008; Zheng, Wei/MSY-7447-2025; Park, Hee-Soo/AAC-6422-2019 | 57218490027; 57221217721; 57214751656; 57204464970; 15751448400; 8648295500; 7405531243 | yyzw@jsnu.edu.cn;jyu1@wisc.edu; | FUNGAL BIOLOGY | FUNGAL BIOL-UK | 1878-6146 | 1878-6162 | 126 | 6-7 | SCIE | MYCOLOGY | 2022 | 2.5 | 65.0 | 0.9 | 2025-06-25 | 8 | 8 | Aspergillus; Velvet; Zn(II)(2)Cys(6) transcription factor; Growth; Secondary metabolism | Aspergillus; Growth; Secondary metabolism; Velvet; Zn(II)<sub>2</sub>Cys<sub>6</sub> transcription factor | Aspergillus nidulans; Fungal Proteins; Gene Expression Regulation, Fungal; RNA, Messenger; Spores, Fungal; Sterigmatocystin; Transcription Factors; fungal protein; messenger RNA; sterigmatocystin; transcription factor; colony; Aspergillus nidulans; fungus spore; gene expression regulation; genetics; metabolism | English | 2022 | 2022 (JUN-JUL) | 10.1016/j.funbio.2022.05.001 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | Busulfan and thiotepa as a conditioning regimen for autologous stem cell transplantation in patients with multiple myeloma | Song, Ga-Young; Jung, Sung-Hoon; Kim, Mihee; Ahn, Seo-Yeon; Ahn, Jae-Sook; Yang, Deok-Hwan; Kim, Hyeong-Joon; Kim, Jin Seok; Eom, Hyeon-Seok; Moon, Joon Ho; Yhim, Ho-Young; Kim, Kihyun; Min, Chang-Ki; Lee, Je-Jung | Chonnam Natl Univ, Hwasun Hosp, Gwangju, South Korea; Yonsei Univ, Coll Med, Seoul, South Korea; Natl Canc Ctr, Seoul, South Korea; Kyungpook Natl Univ Hosp, Daegu, South Korea; Jeonbuk Natl Univ Hosp, Jeonju, South Korea; Samsung Med Ctr, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Internal Med, Seoul, South Korea; Chonnam Natl Univ, Sch Med, Gwangju, South Korea | Kim, Kihyun/D-5175-2013; Kim, Dennis/AAH-8499-2019; Lee, Jung-Hye/F-6974-2013; KIM, JIN/I-6927-2019; Yhim, Ho-Young/J-1531-2012 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | CL LYMPH MYELOM LEUK | 2152-2650 | 2152-2669 | 22 | SCIE | HEMATOLOGY;ONCOLOGY | 2022 | 2.7 | 65.2 | 0 | English | 2022 | 2022-08 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | Meeting Abstract | Clinical impact of time to the best response in relapsed/refractory multiple myeloma patients receiving carfilzomib | Cho, Hee Jeong; Moon, Joon Ho; Kim, Ju-Hyung; Baek, Dong Won; Sohn, Sang-Kyun | Kyungpook Natl Univ Hosp, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Daegu, South Korea | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | CL LYMPH MYELOM LEUK | 2152-2650 | 2152-2669 | 22 | SCIE | HEMATOLOGY;ONCOLOGY | 2022 | 2.7 | 65.2 | 0 | English | 2022 | 2022-08 | 바로가기 | 바로가기 | |||||||||||||||||
| ○ | ○ | Article | Favorable Long-Term Outcomes with Autologous Stem Cell Transplantation for High-Risk Multiple Myeloma Patients with a Positive Result On ¹⁸F-FDG PET/CT at Baseline | To evaluate the role of autologous stem cell transplantation (ASCT) in multiple myeloma patients with a number of focal lesions (FL) >3 on baseline positron emission tomography/computed tomography (PET/CT), we analyzed the medical records of 210 patients. The results showed that patients with FL >3 receiving upfront ASCT have improved survival outcomes compared to those not receiving ASCT. Background: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) is a useful tool for identifying high-risk features in patients with newly diagnosed multiple myeloma (NDMM). This study evaluated the role of autologous stem cell transplantation (ASCT) in patients presenting with positive results on PET/CT scans. Materials and Methods: The medical records of 210 patients who underwent PET/CT at diagnosis were retrospectively reviewed. Eligible patients for transplantation proceeded to upfront ASCT with high-dose chemotherapy (HDT) after induction therapy with novel agents. Results: The presence of a number of focal lesions (FL) >3 and extramedullary disease (EMD) occurred in 111 and 35 patients, respectively. ASCT was performed in 54 patients. Among patients with FL > 3, those treated with ASCT showed a prolonged 2-year progression-free survival (PFS) and overall survival (OS) rates compared to those not treated with ASCT (PFS, 60.2% vs. 23.5%, P 3, Revised International Staging System (R-ISS), and upfront ASCT were independent prognostic factors for PFS and OS. Conclusion: Presenting FL > 3 on baseline PET/CT represents a high-risk feature in patients with NDMM. Frontline ASCT with HDT prolonged the survival of patients with FL > 3. (C) 2021 Elsevier Inc. All rights reserved. | Cho, Hee Jeong; Baek, Dong Won; Kim, Ju-Hyung; Lee, Jungmin; Chung, Yu Kyung; Jung, Sung-Hoon; Song, Ga-Young; Ahn, Seo-Yeon; Ahn, Jae-Sook; Yang, Deok-Hwan; Lee, Je-Jung; Kim, Hyeoung-Joon; Hong, Chae Moon; Jeong, Shin Young; Min, Jung-Joon; Sohn, Sang-Kyun; Moon, Joon Ho | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Hematol Oncol, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Chonnam Natl Univ, Dept Hematol Oncol, Hwasun Hosp, Hwasun, Jeollanamdo, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Nucl Med, Daegu, South Korea; Chonnam Natl Univ, Dept Nucl Med, Hwasun Hosp, Hwasun, South Korea | Lee, Jung-Hye/F-6974-2013 | 57216754907; 57191874272; 58739544500; 57211561890; 57289628500; 55511978300; 57193027251; 55945078500; 22984055900; 8701758000; 7601478211; 7410127473; 37050876700; 36164032500; 7201920094; 13310226800; 56568642700 | jhmoon@knu.ac.kr; | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | CL LYMPH MYELOM LEUK | 2152-2650 | 2152-2669 | 22 | 2 | SCIE | HEMATOLOGY;ONCOLOGY | 2022 | 2.7 | 65.2 | 0.19 | 2025-06-25 | 2 | 2 | Newly diagnosed multiple myeloma; 18F-FDG PET/CT; Focal lesions; Autologous stem cell transplantation; Long-term outcomes | POSITRON-EMISSION-TOMOGRAPHY; EXTRAMEDULLARY DISEASE; BONE-DISEASE; CONSENSUS; LENALIDOMIDE; CHEMOTHERAPY; EXPRESSION; DIAGNOSIS; CRITERIA; IMPACT | 18F-FDG PET/CT; Autologous stem cell transplantation; Focal lesions; Long-term outcomes; Newly diagnosed multiple myeloma | Antineoplastic Combined Chemotherapy Protocols; Fluorodeoxyglucose F18; Hematopoietic Stem Cell Transplantation; Humans; Multiple Myeloma; Positron Emission Tomography Computed Tomography; Prognosis; Retrospective Studies; Stem Cell Transplantation; Transplantation, Autologous; beta 2 microglobulin; bortezomib; calcium; carfilzomib; cyclophosphamide; dexamethasone; fluorodeoxyglucose f 18; immunoglobulin A; immunoglobulin G; lactate dehydrogenase; lenalidomide; melphalan; plasma protein; prednisone; serum albumin; thalidomide; antineoplastic agent; fluorodeoxyglucose f 18; adult; aged; Article; autologous stem cell transplantation; calcium blood level; cancer prognosis; cancer risk; cancer survival; clinical feature; comparative study; contrast enhancement; controlled study; drug megadose; ECOG Performance Status; female; fluorescence in situ hybridization; follow up; globulin blood level; high risk patient; human; human tissue; image display; induction chemotherapy; International Staging System; lactate dehydrogenase blood level; long term survival; major clinical study; male; maximum standardized uptake value; medical record review; multiple myeloma; overall response rate; overall survival; positron emission tomography-computed tomography; progression free survival; retrospective study; treatment response; autotransplantation; diagnostic imaging; hematopoietic stem cell transplantation; multiple myeloma; positron emission tomography-computed tomography; procedures; prognosis; stem cell transplantation | English | 2022 | 2022-02 | 10.1016/j.clml.2021.08.012 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Genetic changes during leukemic transformation to secondary acute myeloid leukemia from myeloproliferative neoplasms | Leukemic transformation (LT) is the main cause of death for patients with myeloproliferative neoplasms (MPNs). To study genetic changes associated with the LT, we performed targeted sequencing in 26 MPN patients including 21 with paired samples. We observed that, besides three driver genes, IDH2 (19%) and ASXL1 (14%) were also frequently mutated at MPN diagnosis. Although variant allele frequencies (VAFs) of mutations in DNA methylation and spliceosome did not expand during LT, they were enriched in patients with LT (the LT group). At follow-up, we also observed acquisition of mutations, mostly in the LT group. When considering dynamics of VAF from diagnosis to follow-up, VAFs in the LT group expanded (median VAF, 36.7-43.7%, p = 0.045). In contrast, mutations in patients with no clinical progression was stable (median VAF, 36.3-35.7%, p = 0.739). Overall, the present study demonstrates genetic changes during LT and provides the potential for prognostic application. | Kim, TaeHyung; Ahn, Jae-Sook; Son, Meong Hi; Novitzky-Basso, Igor; Yi, Seong Yoon; Ahn, Seo-Yeon; Jung, Sung-Hoon; Yang, Deok-Hwan; Lee, Je-Jung; Choi, Seung Hyun; Lee, Ja-yeon; Moon, Joon Ho; Sohn, Sang Kyun; Kim, Hyeoung-Joon; Zhang, Zhaolei; Kim, Dennis Dong Hwan | Univ Toronto, Dept Comp Sci, Toronto, ON, Canada; Univ Toronto, Donnelly Ctr Cellular & Biomol Res, Toronto, ON, Canada; Princess Margaret Canc Ctr, Dept Med Oncol & Hematol, Toronto, ON, Canada; Chonnam Natl Univ, Dept Hematol Oncol, Sch Med, Hwasun, Jeonranam Do, South Korea; Chonnam Natl Univ, Genom Res Ctr Hematopoiet Dis, Sch Med, Hwasun, Jeonranam Do, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Pediat, Sch Med, Seoul, South Korea; Inje Univ Ilsan, Paik Hosp, Dept Internal Med, Goyang, South Korea; Kyungpook Natl Univ Hosp, Dept Hematol Oncol, Daegu, South Korea; Univ Toronto, Dept Mol Genet, Toronto, ON, Canada; Chonnam Natl Univ, Genome Res Ctr Hematopoiet Dis, Sch Med, 322 Seoyang Ro, Hwasun 58128, Jeonranam Do, South Korea; Univ Toronto, Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3E1, Canada; Univ Toronto, Princess Margaret Canc Ctr, 610 Univ Ave, Toronto, ON M5G 2M9, Canada | Kim, Dennis/AAH-8499-2019; Novitzky-Basso, Igor/AAU-2356-2020; Lee, Yong Jae/GLR-4153-2022; Novitzky-Basso, Igor/HKN-5319-2023; Lee, Jung-Hye/F-6974-2013; Kim, Tae/O-4252-2015; Zhang, Zhaolei/G-2369-2017 | 55763792349; 22984055900; 54586032400; 24081143200; 8976421900; 55945078500; 55511978300; 8701758000; 7601478211; 59637966100; 55859183300; 56568642700; 13310226800; 7410127473; 57203273189; 56312200900 | hjoonk@chonnam.ac.kr;zhaolei.zhang@utoronto.ca;dr.dennis.kim@uhn.ca; | LEUKEMIA RESEARCH | LEUKEMIA RES | 0145-2126 | 1873-5835 | 118 | SCIE | HEMATOLOGY;ONCOLOGY | 2022 | 2.7 | 65.2 | 0.19 | 2025-06-25 | 3 | 2 | ESSENTIAL THROMBOCYTHEMIA; PRIMARY MYELOFIBROSIS; POLYCYTHEMIA-VERA; SOMATIC MUTATIONS; CLONAL EVOLUTION; DIAGNOSIS; PROGNOSIS; SURVIVAL; TRANSPLANTATION; CLASSIFICATION | DNA fragment; isocitrate dehydrogenase 2; Janus kinase 2; protein p53; transcription factor; transcription factor RUNX1; acute myeloid leukemia; adult; aged; Article; cell separation; clinical article; cohort analysis; DNA extraction; DNA methylation; female; follow up; gene frequency; gene mutation; genetic analysis; high throughput sequencing; human; male; mononuclear cell; myeloproliferative neoplasm; spliceosome; very elderly | English | 2022 | 2022-07 | 10.1016/j.leukres.2022.106858 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | The association of genetic alterations with response rate in newly diagnosed chronic myeloid leukemia patients | Genetic differences may be associated with the response to tyrosine kinase inhibitor (TKI) in patients with chronic myeloid leukemia (CML). In this study, we identified genetic alterations between rapid and slow responders (BCR/ABL1 International Scale at 6 months: 0.1 %) of TKI treatment in chronic phase CML patients. Our analyses involved single nucleotide polymorphism (SNP), a Genome Wide Association Study and a Network-wide Association Study (NetWAS). Seventy-two patients from 16 institutions were enrolled and treated with a TKI, nilotinib. Gene Set Analysis identified genetic alterations in pathways related to the differentiation, proliferation, and activity of various innate immune cells. The NetWAS analysis found that genes associated with natural killer (NK) cells (PTPRCAP, BLNK, HCK, ARHGEF11, GPR183, TRPV2, SHKBP1, CD2) showed significant differences between rapid and slow responders of nilotinib. However, we found no significantly different genetic alterations according to the response in the SNP analysis. In conclusion, we found that rapidity of response to TKI was associated with pathway-associated genetic alterations in immune cells, particularly with respect to NK cell activity. These results suggested that the innate immune system at initial diagnosis had an important role in treatment response in patients with CML. | Park, Hyunkyung; Kang, Sungbong; Kim, Inho; Kim, Sangsoo; Kim, Hyeong-Joon; Shin, Dong-Yeop; Kim, Dae-Young; Lee, Kyoo-Hyung; Ahn, Jae-Sook; Sohn, Sang-Kyun; Lee, Jeong-Ok; Cheong, June-Won; Kim, Hoon-Gu; Kim, Hawk; Nam, Seung-Hyun; Park, Sang-Gon; Park, Seonyang; Kim, Kyoung Ha; Lee, Yoo Jin; Do, Young Rok; Park, Seong Kyu; Song, Hun Ho; Jung, Chul Won | Seoul Natl Univ, Seoul Metropolitan Govt, Dept Internal Med, Boramae Med Ctr, Seoul, South Korea; Soongsil Univ, Dept Bioinformat & Life Sci, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Biomed Res Inst, Canc Res Inst,Coll Med,Dept Internal Med, Seoul, South Korea; Chonnam Natl Univ, Hwasun Hosp, Dept Internal Med, Hwasun, South Korea; Korea Canc Ctr Hosp, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Dept Internal Med, Coll Med, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea; Yonsei Univ, Severance Hosp, Dept Internal Med, Seoul, South Korea; Soonchunhyang Univ, Dept Internal Med, Seoul Hosp, Seoul, South Korea; Gyeongsang Natl Univ, Gyeongsang Inst Hlth Sci, Dept Internal Med, Coll Med, Chang Won, South Korea; Gyeongsang Natl Univ, Changwon Hosp, Chang Won, South Korea; Ulsan Univ Hosp, Dept Internal Med, Ulsan, South Korea; VHS Med Ctr, Dept Internal Med, Seoul, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Internal Med, Daegu, South Korea; Chosun Univ Hosp, Dept Internal Med, Gwangju, South Korea; Soonchunhyang Univ, Dept Internal Med, Bucheon Hosp, Bucheon, South Korea; Kangdong Sacred Heart Hosp, Dept Internal Med, Seoul, South Korea; Samsung Med Ctr, Dept Internal Med, Seoul, South Korea; Inje Univ, Haeundae Paik Hosp, Dept Internal Med, Busan, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Canc Res Inst, Dept Internal Med,Coll Med, 101 Daehak Ro,Jongno Gu, Seoul 03080, South Korea | ; Lee, Jung-Hye/F-6974-2013; Lee, Jong-Seok/J-5603-2012; Kim, Il Young/LLK-4732-2024; Park, Jinwoo/AAD-1328-2022; Kim, Tae/B-9921-2013; Park, Jung Hyun/HJA-3755-2022 | 57203771773; 57432227800; 55712969800; 57201923850; 7410127473; 36492559200; 56955900700; 38163134100; 22984055900; 13310226800; 40361307900; 7004933294; 7409319096; 35230023400; 57218435122; 57188669696; 55264192100; 8960168300; 42962202500; 57077159400; 7404037551; 56405934800; 57049842400 | ihkimmd@snu.ac.kr;sskimb@ssu.ac.kr; | LEUKEMIA RESEARCH | LEUKEMIA RES | 0145-2126 | 1873-5835 | 114 | SCIE | HEMATOLOGY;ONCOLOGY | 2022 | 2.7 | 65.2 | 0.19 | 2025-06-25 | 2 | 2 | Chronic myeloid leukemia; Tyrosine kinase; Genetic analysis; Molecular response; Natural killer cell | GENOME-WIDE ASSOCIATION; POLYMORPHISM ARRAY ANALYSIS; EXPRESSION SIGNATURE; MOLECULAR RESPONSE; IMATINIB TREATMENT; CML PATIENTS; EXACT TESTS; DISEASE; HAPLOTYPE; TOOL | Chronic myeloid leukemia; Genetic analysis; Molecular response; Natural killer cell; Tyrosine kinase | Fusion Proteins, bcr-abl; Genome-Wide Association Study; Humans; Killer Cells, Natural; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mutation; Protein Kinase Inhibitors; BCR ABL protein; nilotinib; protein tyrosine kinase; BCR ABL protein; protein kinase inhibitor; adult; aged; ARHGEF11 gene; Article; BLNK gene; C3 gene; cancer patient; CD2 gene; cell differentiation; cell proliferation; chronic myeloid leukemia; CLUL1 gene; controlled study; DAPK1 gene; dendritic cell; FCN1 gene; female; gene; gene set analysis; genetic analysis; genetic association; genetic difference; genome-wide association study; GPR183 gene; HCK gene; human; human cell; immunocompetent cell; innate immunity; ITGA3 gene; major clinical study; male; MATK gene; middle aged; natural killer cell; OSBPL10 gene; PLA2G15 gene; prospective study; PTPRCAP gene; RASA2 gene; sex difference; SHKBP1 gene; single nucleotide polymorphism; SLC22A4 gene; treatment response; TRPV2 gene; very elderly; ZBTB6 gene; ZNF217 gene; genetics; genome-wide association study; metabolism; mutation | English | 2022 | 2022-03 | 10.1016/j.leukres.2022.106791 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | Validation of new diagnostic criteria of primary plasma cell leukemia: a study of the Korean Multiple Myeloma Working Party (KMMWP-2003 study) | Jung, Sung-Hoon; Kim, Kihyun; Moon, Joon Ho; Kim, Da-Jung; Kim, Hyo Jung; Kim, Min Kyoung; Kim, Kyoung Ha; Lee, Hyun Jeong; Lee, Ji-Hyun; Kim, Sung-Hyun; Yoo, Kawi Han; Lee, Jae Hoon; Lee, Je-Jung | Chonnam Natl Univ, Hwasun Hosp, Gwangju, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Daegu, South Korea; Kosin Univ, Gospel Hosp, Busan, South Korea; Hallym Univ, Sacred Heart Hosp, Chuncheon Si, South Korea; Yeungnam Univ, Med Ctr, Gyongsan, South Korea; Soonchunhyang Univ, Seoul Hosp, Seoul, South Korea; Kyung Hee Univ, Kyung Hee Univ Hosp, Coll Med, Seoul, South Korea; Dong A Univ, Coll Med, Seoul, South Korea; Gachon Univ, Gil Med Ctr, Seongnam, South Korea; Chonnam Natl Univ, Sch Med, Hwasun Hosp, Gwangju, South Korea | Kim, Pyeong Hwa/KGM-1468-2024; Kim, Hyo/AAQ-3152-2020; Lee, Jeong/JFA-4725-2023; Lee, Jung-Hye/F-6974-2013; Lee, Jinseok/ACF-1247-2022; Lee, Jeong Won/AAC-4169-2022; Kim, Kihyun/D-5175-2013; Kim, Il Young/LLK-4732-2024 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | CL LYMPH MYELOM LEUK | 2152-2650 | 2152-2669 | 22 | SCIE | HEMATOLOGY;ONCOLOGY | 2022 | 2.7 | 65.2 | 0 | English | 2022 | 2022-08 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Article | A Quadruple Coating of Probiotics for Enhancing Intestinal Adhesion and Competitive Exclusion of Salmonella Typhimurium | Previously, our group showed that a quadruple coating of probiotics resulted in higher survivability of probiotics under high acid, bile salt, and thermal stresses. In this study, we evaluated the effect of the quadruple coating of probiotics on adhesive properties as well as on competitive exclusion of Salmonella Typhimurium in Caco-2 cells. We found that the quadruple coating of probiotics exhibited an overall increased adhesion property (up to 10.8-fold) and increased competitive exclusion of Salmonella Typhimurium (up to 4.3-fold). Thus, this study has significant implications and can lead to the development of methods that can improve the adhesive ability of probiotics as well as the adhesive inhibition of pathogens. | Bang, Won Yeong; Kim, Hayoung; Chae, Seung A.; Yang, Soo-Yeon; Ban, O-Hyun; Kim, Tae-Yoon; Kwon, Hyuk-Sang; Jung, Young Hoon; Yang, Jungwoo | Ildong Biosci, 17 Poseunggongdan Ro, Pyeongtaek Si 17957, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Ildong Pharmaceut, Hwaseong Si, Gyeonggi Do, South Korea | ; Jung, Young/F-1703-2013; Kim, Yong-Tae/HQZ-0240-2023 | 57208701768; 57451681800; 57219223373; 57219223890; 57219226382; 57216083538; 56497420600; 55550063700; 56076383700 | younghoonjung@knu.ac.kr;yjw@ildong.com; | JOURNAL OF MEDICINAL FOOD | J MED FOOD | 1096-620X | 1557-7600 | 25 | 2 | SCIE | CHEMISTRY, MEDICINAL;FOOD SCIENCE & TECHNOLOGY;NUTRITION & DIETETICS | 2022 | 2.4 | 65.8 | 1.08 | 2025-06-25 | 10 | 10 | adhesion; microencapsulation; probiotics; quadruple coating; Salmonella Typhimurium | STRAINS | adhesion; microencapsulation; probiotics; quadruple coating; Salmonella Typhimurium | Bacterial Adhesion; Caco-2 Cells; Humans; Probiotics; Salmonella typhimurium; hyaluronic acid; probiotic agent; antibacterial activity; Article; Caco-2 cell line; competitive exclusion; encapsulation; growth inhibitory concentration; intestine; microbial adhesion; microencapsulation; nonhuman; Salmonella enterica serovar Typhimurium; temperature stress; bacterium adherence; human | English | 2022 | 2022-02-01 | 10.1089/jmf.2021.k.0117 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Soaking Soybean Seeds with Abeliophyllum distichum Nakai Extract Increased the Yield and Nutritional Value of Soybean Sprouts | Abeliophyllum distichum Nakai, an ornamental plant, contains a wide range of phytochemicals having pharmaceutical properties. The use of dif- ferent plant-based extracts for the enhancement of yield and/or quality of soybean sprouts, one of the most inexpensive but nutritious food products, is common. The objective of this study was to examine the effect of A. distichum flower extract (ADE) on the yield and nutritional value of soybean sprouts. Soybean seeds were soaked in ADE solutions with concentrations (w/v) of 0.5% (ADE-0.5), 1% (ADE-1), 3% (ADE-3), and 5% (ADE-5). The effect of ADE concentration on the yield and different nutrient components varied. The highest soybean sprout yield and vitamin C content were found with ADE-3. The most abundant essential amino acid content was detected in ADE-1, whereas the greatest amounts of total isoflavones and to- tal minerals were determined in ADE-5 and the ADE-untreated control, respectively. Overall results of yield, color, and contents of vitamin C, amino acids, and isoflavones suggest that 1% or 3% of A. distichum extract could be an optimum concentration to soak the soybean seeds for higher sprout yield and nutrient content. | Kim, Jeong-Ho; Yoon, Yong-Han; Kim, Il-Doo; Dhungana, Sanjeev Kumar; Shin, Dong-Hyun | Konkuk Univ, Dept Green Technol Convergence, Chungju 27478, South Korea; Kyungpook Natl Univ, Int Inst Res & Dev, Daegu 41566, South Korea; Natl Inst Crop Sci, Dept Southern Area Crop Sci, Rural Dev Adm, Miryang 50424, South Korea; Rural Dev Adm, Miryang 50424, South Korea | Kim, Il-Doo/C-1850-2011; Kim, Jeong-Ho/A-7641-2018; Dhungana, Sanjeev Kumar/O-4097-2017 | 57221537227; 56230173600; 56269995600; 56269940800; 7403352903 | dhshin@knu.ac.kr; | POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES | POL J FOOD NUTR SCI | 1230-0322 | 2083-6007 | 72 | 2 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2022 | 2.4 | 65.8 | 0 | 2025-06-25 | 0 | 0 | amino acid; color parameters; isoflavone; mineral; vitamin C | ANTIOXIDANT; ZINC; BIOFORTIFICATION; FERMENTATION; SELENIUM; QUALITY; IRON | amino acid; color parameters; isoflavone; mineral; vitamin C | English | 2022 | 2022 | 10.31883/pjfns/147520 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Dimorphism and microcycle conidiation of Pseudocercospora pseudostigmina-platani conidia from American sycamore | In this study, the micromorphology and surface details of Pseudocercospora pseudostigmina-platani conidia were investigated on American sycamore (Platanus occidentalis) leaves. Sooty films were collected from diseased leaves for fungal DNA extraction and observed using light and field-emission scanning electron microscopy. Two types of conidia were present on the leaves: (i) hyaline and curved Cercostigmina-like conidia and (ii) brown and straight Stigmina-like conidia. The fungal pathogen was identified as P. pseudostigmina-platani based on morphological characteristics and internal transcribed spacer region sequences. Some non-glandular trichomes were found near the centre of the conidial masses on the abaxial surface of the naturally infected leaves. Leaf ultrasonication to dislodge conidia revealed sporodochia erupting through the stomata. Hyphae from sporodochia grew on the leaf surface and entered host tissues through the stomata. Conidiogenous cells had terminal rings and tapered towards the flat region where a conidium was attached. The conidia produced secondary conidia directly without hyphae. After dislodging the conidia by ultrasonication, scars were observed. These results indicate that the fungus has dimorphic conidia and microcycle conidiation for simple and rapid asexual reproduction. | Park, Junhyung; Seo, Dahye; An, Hwa-Yong; Park, Ji-Hyun; Kim, Ki Woo | Kyungpook Natl Univ, Dept Ecol & Environm Syst, Sangju 37224, South Korea; Seoul Natl Univ, Natl Instrumentat Ctr Environm Management, Seoul, South Korea; Natl Inst Forest Sci, Div Forest Dis & Insect Pests, Seoul, South Korea; Kyungpook Natl Univ, Tree Diagnost Ctr, Sangju, South Korea | Park, Ji/ABG-5893-2020; Kim, Ki Woo/AAC-5623-2022 | 57202928407; 57218319875; 57216223810; 56918798800; 57201369889 | kiwoo@knu.ac.kr; | FOREST PATHOLOGY | FOREST PATHOL | 1437-4781 | 1439-0329 | 52 | 6 | SCIE | FORESTRY | 2022 | 1.4 | 65.9 | 0.13 | 2025-06-25 | 1 | 1 | Cercospora; Mycosphaerella; Platanus; Stigmina; trichome | 1ST REPORT; MYCOSPHAERELLA; OCCIDENTALIS | Cercospora; Mycosphaerella; Platanus; Stigmina; trichome | asexual reproduction; fungal disease; fungus; micromorphology; pathogen; trichome | English | 2022 | 2022-12 | 10.1111/efp.12777 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Quality Differentiation and Spatial Clustering among Restaurants * | To explore the relationship between spatial location and quality differentiation, we build a dataset of over 30,0 0 0 restaurants rated by TripAdvisor, across large UK cities. We document several new stylized facts. Top -rated restaurants tend to be spatially more concentrated around the city center than bottom -rated ones. Whereas top -rated restaurants tend to locate close to other top restaurants, bottom -rated restaurants tend to locate away from each other and closer to top -rated ones. Our theoretical model can explain the main features of observed spatial patterns. Consistently with the predictions of our model, our regression analysis finds that an increase in the population density in the city center is associated with a decrease in the spatial dispersion of both top and bottom restaurants, this reduction being larger in magnitude for top ones. Also, a larger quality difference between top and bottom restaurants increases both the absolute and relative dispersion of top restaurants. (c) 2021 Elsevier B.V. All rights reserved. | Mossay, Pascal; Shin, Jong Kook; Smrkolj, Grega | Kyungpook Natl Univ, Dept Econ, Daegu, South Korea; Korea Univ, Dept Econ & Stat, Sejong Campus, Sejong Si, South Korea; Newcastle Univ Business Sch, 5 Barrack Rd, Newcastle Upon Tyne NE1 4SE, England | ; Smrkolj, Grega/GYE-0258-2022 | 56418345000; 36451195900; 55807109900 | pascal.mossay@knu.ac.kr;jongkookshin@korea.ac.kr;Grega.Smrkolj@newcastle.ac.uk; | INTERNATIONAL JOURNAL OF INDUSTRIAL ORGANIZATION | INT J IND ORGAN | 0167-7187 | 1873-7986 | 80 | SSCI | ECONOMICS | 2022 | 1.5 | 65.9 | 0.36 | 2025-06-25 | 3 | 4 | Spatial competition; Quality differentiation; Hotelling model; Restaurant industry | Hotelling model; Quality differentiation; Restaurant industry; Spatial competition | Competition; Dispersions; Large dataset; Population statistics; City centers; Hotelling model; Quality differentiation; Restaurant industry; Spatial clustering; Spatial competition; Spatial location; Spatial quality; Stylized facts; Theoretical modeling; Regression analysis | English | 2022 | 2022-01 | 10.1016/j.ijindorg.2021.102799 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | The Relationship Between Comorbidities and Microbiologic Findings in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease | Purpose: Data regarding the relationship between microbiologic features and comorbidities in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are limited. The aim of this study was to correlate microbiologic findings with comorbidities in patients with moderate to severe AECOPD. Patients and Methods: This multicenter observational study included patients with AECOPD seen at 28 hospitals in South Korea between January 2015 and December 2018, and the data were retrospectively collected. Pathogens were examined in patients with either pulmonary or extrapulmonary comorbidities, and compared to those of patients without comorbidities. The relationship between pathogen type and the number of comorbidities was also evaluated. Results: Bacterial infections (178 [37.2%] vs 203 [28.7%], p = 0.002) and co-infections with bacteria and viruses (65 [13.6%] vs 57 [8.1%], p = 0.002) were more prevalent in patients with pulmonary comorbidities. Bacterial pathogens (280 [34.7%] vs 101 [26.7%], p=0.006) were detected at a higher rate in patients with extrapulmonary comorbidities. Previous pulmonary tuberculosis (PTB), bronchiectasis, and diabetes mellitus were risk factors for bacterial infection, and congestive heart failure was a risk factor for bacterial and viral co-infection. As the number of comorbidities increased, the risk of bacterial infection increased considerably. Pseudomonas aeruginosa was more frequently identified in patients with previous PTB (57 [15.3%] vs 59 [7.4%], p < 0.001) and bronchiectasis (33 [19.6%] vs 83 [8.3%], p < 0.001). Conclusion: AECOPD patients with comorbidities were more likely to experience infection-related exacerbations compared to those without comorbidities. As the overall number of comorbidities increased, the risk of bacterial infection increased significantly. | Seo, Hyewon; Sim, Yun Su; Min, Kyung Hoon; Ha Lee, Jae; Kim, Byung-Keun; Oh, Yeon Mok; Ra, Seung Won; Kim, Tae-Hyung; Hwang, Yong Il; Park, Jeong-Woong | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kangnam Sacred Heart Hosp, Div Pulm Allergy & Crit Care Med, Seoul, South Korea; Korea Univ, Guro Hosp, Coll Med, Div Pulmonol,Dept Internal Med, Seoul, South Korea; Inje Univ, Haeundae Paik Hosp, Coll Med, Div Pulmonol & Crit Care Med,Dept Internal Med, Busan, South Korea; Korea Univ, Coll Med, Anam Hosp, Div Pulmonol Allergy & Crit Care Med,Dept Interna, Seoul, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pulm & Crit Care Med, Seoul, South Korea; Univ Ulsan, Ulsan Univ Hosp, Coll Med, Dept Internal Med, Ulsan, South Korea; Hanyang Univ, Guri Hosp, Coll Med, Div Pulm & Crit Care Med, Guri, South Korea; Hallym Univ, Sacred Heart Hosp, Coll Med, Div Pulm Allergy & Crit Care Med,Dept Med, Anyang, South Korea; Gachon Univ, Gil Med Ctr, Dept Allergy Pulm & Crit Care Med, Namdong Daero 774 Beon Gil, Incheon 21565, South Korea | Min, Kyung/C-5984-2019; Ra, Seung Won/KYI-0974-2024; kim, sang-soo/C-6573-2009; Kim, Byung-Keun/N-4256-2018; HWANG, YONG/AAU-7121-2021; HWANG, YONG IL/AAU-7121-2021; Min, Kyung Hoon/C-5984-2019 | 55612130200; 8879185900; 57077706300; 57112077000; 36608393400; 7402125922; 36515395700; 58961778000; 34570249800; 56746443700 | jwpark@gilhospital.com; | INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE | INT J CHRONIC OBSTR | 1178-2005 | 17 | SCIE | RESPIRATORY SYSTEM | 2022 | 2.8 | 65.9 | 1.12 | 2025-06-25 | 9 | 9 | chronic obstructive pulmonary disease; acute exacerbation; comorbidity; bacteria; virus | COPD EXACERBATIONS; BRONCHIECTASIS; TUBERCULOSIS; INFLAMMATION; INFECTION; BACTERIAL; ADULTS; IMPACT; COSTS | acute exacerbation; bacteria; chronic obstructive pulmonary disease; comorbidity; virus | Bacteria; Bacterial Infections; Bronchiectasis; Coinfection; Humans; Lung; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Virus Diseases; beta adrenergic receptor stimulating agent; corticosteroid; immunoglobulin M; long acting drug; muscarinic receptor blocking agent; xanthine derivative; Adenoviridae; aged; Article; bacterial infection; bacterium identification; bronchiectasis; chronic obstructive lung disease; coinfection; comorbidity; congestive heart failure; controlled study; correlation analysis; diabetes mellitus; disease association; disease exacerbation; disease severity; Escherichia coli; female; forced expiratory volume; host microbe interaction; human; Human respiratory syncytial virus; hypertension; Influenza A virus; interstitial lung disease; Klebsiella pneumoniae; lung function test; lung tuberculosis; major clinical study; male; Metapneumovirus; multiplex reverse transcription polymerase chain reaction; Mycoplasma pneumoniae; nonhuman; observational study; Pneumovirus; prevalence ratio; Pseudomonas aeruginosa; retrospective study; Rhinovirus; risk factor; South Korea; Streptococcus pneumoniae; virus identification; virus infection; bacterial infection; bacterium; bronchiectasis; chronic obstructive lung disease; clinical trial; coinfection; lung; microbiology; multicenter study; virus infection | English | 2022 | 2022 | 10.2147/copd.s360222 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Enhanced switching ratio of sol-gel-processed Y2O3 RRAM device by suppressing oxygen vacancy formation at high annealing temperatures | Sol-gel-processed Y2O3 films were used as an active-channel layer for resistive switching memory (RRAM) devices. The influence of post-annealing temperature on structural, chemical, and electrical properties was studied. Y2O3-RRAM devices comprising electrochemically active metal electrodes, Ag, and indium tin oxide (ITO) electrodes exhibited the conventional bipolar RRAM device operation. The fabricated Ag/Y2O3/ITO RRAM devices, which included 500 degrees C-annealed Y2O3 films, exhibited less oxygen vacancy and defect sites, reduced the leakage current, increased the high-/low-resistance state ratio of more than 10(5), and provided excellent nonvolatile memory properties without significant deterioration for 100 cycles and 10(4) s. | Kim, Kyoungdu; Lee, Changmin; Lee, Won-Yong; Kim, Do Won; Kim, Hyeon Joong; Lee, Sin-Hyung; Bae, Jin-Hyuk; Kang, In-Man; Jang, Jaewon | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | Lee, Sin-Hyung/ABD-6425-2022; Kim, Byung Joo/ABG-7715-2021; Kim, Do-Yeon/B-1877-2009 | 57221754528; 57191709616; 57209527128; 59110033500; 57221742722; 57226880204; 35326180700; 7203062678; 57194107504 | j1jang@knu.ac.kr; | SEMICONDUCTOR SCIENCE AND TECHNOLOGY | SEMICOND SCI TECH | 0268-1242 | 1361-6641 | 37 | 1 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;MATERIALS SCIENCE, MULTIDISCIPLINARY;PHYSICS, CONDENSED MATTER | 2022 | 1.9 | 66.4 | 1.22 | 2025-06-25 | 15 | 15 | sol-gel; Y2O3; resistive random access memory; oxygen vacancy; electrochemical metallization cell | MEMORY; STABILITY; CIRCUIT; SET | electrochemical metallization cell; oxygen vacancy; resistive random access memory; sol-gel; Y<sub>2</sub>O<sub>3</sub> | Annealing; Deterioration; Electrodes; Metals; Oxygen; Oxygen vacancies; RRAM; Sol-gels; Tin oxides; Active channel layers; Active metals; Annealing temperatures; Postannealing temperatures; Random access memory; Resistive random access memory; Resistive switching memory; Sol'gel; Vacancy formation; Y2O3 films; Sol-gel process | English | 2022 | 2022-01 | 10.1088/1361-6641/ac3dd3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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