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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Post-Neutron Mass Yield Distribution in the Spontaneous Fission of ²⁵²Cf | Cumulative and independent yields of various fission products within mass ranges of 86 to 119 and 127 to 162 were measured in the spontaneous fission of Cf-252 by using an off-line gamma-ray spectrometric technique. From the cumulative yields of the fission products, their mass chain yields were obtained by using the charge distribution correction. Mass yield distribution parameters such as full-width at tenth-maximum of light and heavy mass wings, average light mass and heavy mass , and total average neutron multiplicity (expt) were obtained. Fission yield data in the Cf-252(SF) reaction were compared with similar data in neutron-induced fission and spontaneous fission of other actinides to examine the role of excitation energy and nuclear structure effect. The role of standard I and standard II asymmetric modes of fission is also discussed. | Naik, H.; Dange, S. P.; Jang, W.; Singh, R. J. | Bhabha Atom Res Ctr, Radiochem Div, Mumbai 400085, Maharashtra, India; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea | 7005890232; 6602557752; 59777352500; 24322531600 | naikhbarc@yahoo.com; | NUCLEAR SCIENCE AND ENGINEERING | NUCL SCI ENG | 0029-5639 | 1943-748X | 195 | 7 | SCIE | NUCLEAR SCIENCE & TECHNOLOGY | 2021 | 1.46 | 63.2 | 0.31 | 2025-07-30 | 4 | 4 | Cf-252(SF) reaction; off-line gamma-ray spectrometry; measured fission product yields; mass yield distribution parameters | CUMULATIVE YIELDS; ISOTOPES; CHARGE | <sup>252</sup>Cf(SF) reaction; mass yield distribution parameters; measured fission product yields; off-line gamma-ray spectrometry | Actinides; Fission products; Gamma rays; Neutron detectors; Neutrons; Asymmetric modes; Distribution parameters; Neutron multiplicity; Neutron-induced fission; Nuclear structure; Similar datum; Spectrometric techniques; Spontaneous fission; Fission reactions | English | 2021 | 2021-07-03 | 10.1080/00295639.2020.1866389 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical impact of radioactive iodine dose selection based on the number of metastatic lymph nodes in patients with papillary thyroid carcinoma: A multicenter retrospective cohort study | Objective The aim of this study is to investigate whether the number of metastatic lymph nodes (LNs) could be used as a basis in the radioactive iodine (RAI) dose selection for patients with papillary thyroid carcinoma (PTC). Patients A total of 595 patients with PTC who received first RAI therapy after total or near-total thyroidectomy and had no evidence of disease in treatment response assessment were retrospectively enroled from five hospitals. The patients were classified into two subgroups based on the number of metastatic LNs (>5). The multivariate Cox-proportional hazard model was performed to identify the significant factors for recurrence prediction in each group as well as all enroled patients. Results Overall, 22 (3.7%) out of 595 patients had the recurrent disease during the follow-up period. The number of metastatic LNs (>5) was only a significant factor for recurrence prediction in all enroled patients (odds ratio: 7.834, p = 3.7 GBq) therapy significantly lowered the recurrence rate in patients with more than five metastatic LNs. Therefore, RAI dose should be determined based on the number of metastatic LNs as well as conventional risk factors. | Kwon, Seong Young; Kim, Myoung Hyoun; Kong, Eunjung; Chong, Ari; Yoo, Su Woong; Jeon, Subin; Park, Soon-Ah; Kim, Dae-Weung; Kang, Su Hwan; Choi, Jung Eun; Ha, Jung-Min; Jeong, Shin Young; Lee, Sang-Woo | Chonnam Natl Univ, Sch Med, Dept Nucl Med, Jeonnam, South Korea; Chonnam Natl Univ, Hwasun Hosp, Jeonnam, South Korea; Wonkwang Univ, Sch Med, Dept Nucl Med, Jeollabuk Do, South Korea; Yeungnam Univ, Sch Med & Hosp, Dept Nucl Med, Daegu, South Korea; Chosun Univ Hosp, Dept Nucl Med, Gwangju, South Korea; Yeungnam Univ, Med Sch & Hosp, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Nucl Med, 807 Hoguk Ro, Daegu 41404, South Korea; Kyungpook Natl Univ, Chilgok Hosp, 807 Hoguk Ro, Daegu 41404, South Korea | ; Kwon, Seong-Young/AAU-3101-2021; Ha, Jungmin/JAC-1760-2023; lee, sangwoo/KUD-1906-2024 | 40261965600; 55603873600; 37007708500; 26533830900; 37103136400; 57203152128; 23970929400; 34770738200; 57217378204; 56327120300; 57205819153; 36164032500; 57196249819 | swleenm@knu.ac.kr; | CLINICAL ENDOCRINOLOGY | CLIN ENDOCRINOL | 0300-0664 | 1365-2265 | 95 | 6 | SCIE | ENDOCRINOLOGY & METABOLISM | 2021 | 3.523 | 63.4 | 0.09 | 2025-07-30 | 1 | 3 | metastatic lymph node; papillary thyroid carcinoma; radioactive iodine; recurrence | POSTOPERATIVE RADIOIODINE THERAPY; CANCER PATIENTS; RISK; ABLATION; MANAGEMENT; SURVIVAL; YOUNGER; I-131; RATIO | metastatic lymph node; papillary thyroid carcinoma; radioactive iodine; recurrence | Carcinoma, Papillary; Humans; Iodine Radioisotopes; Lymph Nodes; Neoplasm Recurrence, Local; Retrospective Studies; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroidectomy; liothyronine; radioactive iodine; recombinant thyrotropin; thyroglobulin; thyrotropin; radioactive iodine; adult; aged; Article; biopsy; cancer recurrence; cancer staging; cancer surgery; cohort analysis; controlled study; female; follow up; human; low iodine diet; lymph node metastasis; major clinical study; male; middle aged; prediction; radiotherapy dosage; recurrence risk; recurrent disease; retrospective study; thyroglobulin blood level; thyroid papillary carcinoma; thyroidectomy; thyrotropin blood level; treatment response; clinical trial; lymph node; multicenter study; papillary carcinoma; thyroid tumor; tumor recurrence | English | 2021 | 2021-12 | 10.1111/cen.14544 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Letter | Commentary on Winzeler et al 'Low arginine vasopressin levels in patients with diabetes insipidus are not associated with anaemia' | Mayer, Balazs; Nemeth, Krisztian; Krepuska, Miklos; Myneni, Vamsee D.; Maric, Dragan; Tisdale, John F.; Hsieh, Matthew M.; Uchida, Naoya; Lee, Heon-Jin; Nemeth, Michael J.; Holmbeck, Kenn; Noguchi, Constance Tom; Rogers, Heather; Dey, Soumyadeep; Hansen, Arne; Hong, Jeffrey; Chow, Ian; Key, Sharon; Szalayova, Ildiko; Pagani, Jerome; Marko, Karoly; MacClain-Caldwell, Ian; Vitale-Cross, Lynn; Young, W. Scott, III; Brownstein, Michael J.; Mezey, Eva | Natl Inst Dent & Craniofacial Res, Adult Stem Cell Sect, Craniofacial & Skeletal Dis Branch, HHS,NIH, Bethesda, MD 20892 USA; Semmelweis Univ, Dept Dermatol Venereol & Dermatooncol, Budapest, Hungary; NINDS, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA; NHLBI, Mol & Clin Hematol Branch, NIH, Bldg 10, Bethesda, MD 20892 USA; NIMH, Sect Neural Gene Express, NIH, Bethesda, MD 20892 USA; Kyungpook Natl Univ, Sch Dent, Dept Oral Microbiol & Immunol, Daegu, South Korea; Roswell Park Canc Inst, Dept Immunol, Buffalo, NY USA; NIDDK, Mol Med Branch, NIH, Bethesda, MD 20892 USA; NIMH, Bethesda, MD 20892 USA | ; Mezey, Eva/A-8105-2008; Nemeth, Krisztian/LDG-3125-2024; Uchida, Naoya/KHD-4811-2024; Young, Walter/A-9333-2009 | 8862176100; 23005318900; 26323748500; 37461902000; 7005112919; 7005880748; 8941270200; 7201528384; 36462383000; 7006309685; 6602337156; 7006350622; 14634911000; 55599572000; 57193618066; 57198517298; 57198500053; 7006791219; 7801465107; 8621124500; 6701790916; 57220637267; 6506153060; 7402257467; 7102584033; 7102387246 | mayer.balazs@med.semmelweis-univ.hu;mkrepuska@gmail.com; | CLINICAL ENDOCRINOLOGY | CLIN ENDOCRINOL | 0300-0664 | 1365-2265 | 94 | 5 | SCIE | ENDOCRINOLOGY & METABOLISM | 2021 | 3.523 | 63.4 | 0.24 | 2025-07-30 | 1 | 1 | Anemia; Arginine Vasopressin; Diabetes Insipidus; Diabetes Mellitus; Humans; argipressin; desmopressin; hemoglobin; nicotine; vasopressin V1b receptor; vasopressin V2 receptor; argipressin; anemia; diabetes insipidus; disease association; erythrocyte count; erythrocyte lifespan; erythropoiesis; genetic difference; hematocrit; hematopoietic stem cell; hemoglobin determination; human; Letter; natural selection; patient compliance; polydipsia; priority journal; United States; diabetes mellitus | English | 2021 | 2021-05 | 10.1111/cen.14377 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Documenting a Geographical Issue and Its Consequences Using Photovoice as a Pedagogical Tool in Geography Education | This study examines the application of photovoice as a pedagogical tool in a geography class. The main stages of photovoice were modified to suit the context for learning about a geographical issue, animal rights in relation to street cats in South Korea. Data were collected, and grounded theory was applied for the analysis. Based on the results, the paper discusses the implications of photovoice as a pedagogical tool for helping student learn geography by studying place/community as well as engaging in active learning and citizenship, authentic learning and assessment, and social justice and change in a critical geographic context. | Cho, Chul-Ki; Kim, Byung-Yeon; Stoltman, Joseph | Kyungpook Natl Univ, Dept Geog Educ, Daegu, South Korea; Dasa High Sch, Daegu, South Korea; Western Michigan Univ, Mallinson Inst Sci Educ, Dept Geog, Kalamazoo, MI 49008 USA | ; KIM, BYUNGYEON/HTP-3607-2023 | 57221970337; 57221967006; 6602898699 | ckcho@knu.ac.kr; | JOURNAL OF GEOGRAPHY | J GEOGR | 0022-1341 | 1752-6868 | 120 | 2 | SSCI | GEOGRAPHY | 2021 | 2.043 | 63.4 | 0.51 | 2025-07-30 | 4 | 5 | Photovoice; geographical issue; critical pedagogy; active learning and citizenship; authentic learning and assessment; social justice and change | authentic learning and assessment; critical pedagogy; active learning and citizenship; geographical issue; Photovoice; social justice and change | South Korea; animal welfare; assessment method; citizenship; geography education; learning; social change; social justice; theoretical study | English | 2021 | 2021-03-04 | 10.1080/00221341.2021.1875497 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Progression to prediabetes or diabetes in young Korean women with polycystic ovary syndrome: A longitudinal observational study | Objective To investigate changes in glycaemic status in women with polycystic ovary syndrome (PCOS). Design Longitudinal observational study. Patients Women with PCOS who underwent baseline and follow-up screening tests for diabetes (n = 262). Four patients with type 2 diabetes (T2DM) at baseline and 6 patients who were taking drugs at the final follow-up were excluded. Measurements Changes in glycaemic classification based on fasting glucose, haemoglobin A1c and oral glucose tolerance test. Results The median length of follow-up was 2.9 years. The mean age and body mass index in the normoglycaemia group (n = 202) were 23.0 years and 21.6 kg/m(2), while it was 23.6 years and 22.9 kg/m(2) in the prediabetes group (n = 50). In the normoglycaemia group, 38 (18.8%) and 2 (1.0%) developed prediabetes and T2DM, respectively. In the prediabetes group, 22 (44.0%) remained in the same category, 6 (12.0%) developed T2DM, while 22 (44.0%) achieved normoglycaemia. The incidence rate of T2DM was 9.3 per 1,000 person-years, which was significantly higher than that of the female population of similar age, and the incidence was higher in women with fasting glucose >= 5.6 mmol/L at baseline than in women with 5.6 mmol/L. Conclusions About 20% of normoglycaemic women had developed prediabetes or T2DM after a median time of 2.9 years. Meanwhile, nearly half of prediabetes women achieved normoglycaemia. Higher baseline fasting glucose levels were associated with an increased incidence of T2DM. Our results are the first to evaluate glycaemic status changes using all three parameters in patients with PCOS. | Choi, Young Min; Hwang, Kyu Ri; Oh, So Hee; Lee, Dayong; Chae, Soo Jin; Yoon, Sang Ho; Kim, Jin Ju | Seoul Natl Univ, Dept Obstet & Gynecol, Coll Med, Seoul, South Korea; Seoul Natl Univ, Coll Med, Med Res Ctr, Inst Reprod Med & Populat, Seoul, South Korea; SMG SNU Boramae Med Ctr, Dept Obstet & Gynecol, Seoul, South Korea; SMG SNU Boramae Med Ctr, Dept Biostat, Seoul, South Korea; Kyungpook Natl Univ, Dept Obstet & Gynecol, Sch Med, Daegu, South Korea; IORA Fertil Clin, Dept Obstet & Gynecol, Suwon, South Korea; Dongguk Univ, Sch Med, Dept Obstet & Gynecol, Seoul, South Korea; Seoul Natl Univ Hosp, Healthcare Syst Gangnam Ctr, Dept Obstet & Gynecol, Seoul 06236, South Korea | 34871460300; 14421004300; 55509767900; 57193077140; 24472652300; 55232199500; 57192987416 | kimjinju0514@gmail.com; | CLINICAL ENDOCRINOLOGY | CLIN ENDOCRINOL | 0300-0664 | 1365-2265 | 94 | 5 | SCIE | ENDOCRINOLOGY & METABOLISM | 2021 | 3.523 | 63.4 | 0.63 | 2025-07-30 | 7 | 7 | Diabetes; Glycaemic status; Polycystic ovary syndrome; Prediabetes | IMPAIRED GLUCOSE-TOLERANCE; RISK-FACTOR; HEMOGLOBIN; MELLITUS; COHORT | Diabetes; Glycaemic status; Polycystic ovary syndrome; Prediabetes | Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Polycystic Ovary Syndrome; Prediabetic State; Republic of Korea; glucose; hemoglobin A1c; adolescent; adult; age; Article; body mass; controlled study; diabetes mellitus; disease exacerbation; female; follow up; gender; glucose blood level; human; impaired glucose tolerance; incidence; Korean (people); longitudinal study; major clinical study; non insulin dependent diabetes mellitus; observational study; oral glucose tolerance test; ovary polycystic disease; priority journal; screening test; glucose tolerance test; impaired glucose tolerance; non insulin dependent diabetes mellitus; South Korea | English | 2021 | 2021-05 | 10.1111/cen.14416 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical Outcomes of Biportal Endoscopic Interlaminar Decompression with Oblique Lumbar Interbody Fusion (OLIF): Comparative Analysis with TLIF | Oblique lumbar interbody fusion (OLIF) improves the spinal canal, with favorable clinical outcomes. However, it may not be useful for treating concurrent, severe central canal stenosis (SCCS). Therefore, we added biportal endoscopic spinal surgery (BESS) after OLIF, evaluated the combined procedure for one-segment fusion with clinical outcomes, and compared it to open conventional TLIF. Patients were divided into two groups: Group A underwent BESS with OLIF, and Group B were treated via TLIF. The length of hospital stay (LOS), follow-up period, operative time, estimated blood loss (EBL), fusion segment, complications, and clinical outcomes were evaluated. Clinical outcomes were measured using Visual Analog Scale (VAS) scores, Oswestry Disability Index (ODI) scores, and the modified Macnab criteria. All the clinical parameters improved significantly after the operation in Group A. The only significant between-group difference was that the EBL was significantly lower in Group A. At the final follow-up, no clinical parameter differed significantly between the groups. No complications developed in either group. We suggest that our combination technique is a useful, alternative, minimally invasive procedure for the treatment of one-segment lumbar SCCS associated with foraminal stenosis or segmental instability. | Lee, Ho-Jin; Park, Eugene J.; Ahn, Jae-Sung; Kim, Sang Bum; Kwon, Youk-Sang; Park, Young-Cheol | Chungnam Natl Univ, Dept Orthopaed Surg, Coll Med, Daejeon 35015, South Korea; Kyungpook Natl Univ, Dept Orthopaed Surg, Sch Med, Daegu 41405, South Korea; Daejeon Centum Hosp, Dept Orthopaed Surg, Daejeon 35209, South Korea; Special Warfare Command, Special Mission Brigade 13, Med Battal, Dept Orthopaed Surg, Chungbuk 28644, South Korea | Park, Eugene/P-1473-2018 | 57200952141; 55371642100; 35739566800; 57195935883; 57210132800; 57204706969 | leeleo98@gmail.com;pjj841229@gmail.com;jsahn@cnu.ac.kr;sangbumos@me.com;ortho82@gmail.com;ycyeh0830@hanmail.net; | BRAIN SCIENCES | BRAIN SCI | 2076-3425 | 11 | 5 | SCIE | NEUROSCIENCES | 2021 | 3.333 | 63.8 | 1.51 | 2025-07-30 | 16 | 19 | lumbar vertebrae; biportal endoscopy; oblique lateral interbody fusion; minimally invasive surgery; severe central canal stenosis; foraminal stenosis; segmental instability | SPINAL SURGERY; COMPLICATIONS | Biportal endoscopy; Foraminal stenosis; Lumbar vertebrae; Minimally invasive surgery; Oblique lateral interbody fusion; Segmental instability; Severe central canal stenosis | Article; bleeding; brain hernia; discectomy; hospitalization; intermittent claudication; leg pain; length of stay; liver cell carcinoma; nonhuman; nuclear magnetic resonance imaging; operation duration; operative blood loss; paresthesia; posterior lumbar interbody fusion; pubis symphysis; scoliosis; scoring system; spine fusion; spine surgery; stenosis | English | 2021 | 2021-05 | 10.3390/brainsci11050630 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Current-Component Independent Transition Form Factors for Semileptonic and Rare DLongRightArrow;πK Decays in the Light-Front Quark Model | We investigate the exclusive semileptonic and rare DLong Right Arrow;πK decays within the standard model together with the light-front quark model (LFQM) constrained by the variational principle for the QCD-motivated effective Hamiltonian. The form factors are obtained in the q+=0 frame and then analytically continue to the physical timelike region. Together with our recent analysis of the current-component independent form factors f±q2 for the semileptonic decays, we present the current-component independent tensor form factor fTq2 for the rare decays to make the complete set of hadronic matrix elements regulating the semileptonic and rare DLong RightArrow;πK decays in our LFQM. The tensor form factor fTq2 are obtained from two independent sets JT+⊥,JT+- of the tensor current JTuv. As in our recent analysis of f-q2, we show that fTq2 obtained from the two different sets of the current components gives the identical result in the valence region of the q+=0 frame without involving the explicit zero modes and the instantaneous contributions. The implications of the zero modes and the instantaneous contributions are also discussed in comparison between the manifestly covariant model and the standard LFQM. In our numerical calculations, we obtain the q2-dependent form factors (f±,fT) for DLongRightArrow;πK and branching ratios for the semileptonic DLongRightArrow;πKℓvℓℓ=e,μ decays. Our results show in good agreement with the available experimental data as well as other theoretical model predictions. © 2021 Ho-Meoyng Choi. | Choi, Ho-Meoyng | Department of Physics, Teachers College, Kyungpook National University, Daegu, 702-701, South Korea | 7404339783 | homyoung@knu.ac.kr; | Advances in High Energy Physics | ADV HIGH ENERGY PHYS | 1687-7357 | 1687-7365 | 2021 | SCIE | PHYSICS, PARTICLES & FIELDS | 2021 | 1.771 | 63.8 | 0.44 | 2025-07-30 | 6 | Approximation theory; Decay (organic); Elementary particles; Current component; Effective Hamiltonian; Form factors; Independent transitions; Quark model; Rare decays; Semileptonic decay; Tensor forms; The standard model; Variational principles; Tensors | English | Final | 2021 | 10.1155/2021/4277321 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Enhancement of Galactose Uptake fromKappaphycus alvareziiHydrolysate UsingSaccharomyces cerevisiaeThrough Overexpression of Leloir Pathway Genes | A total 42.68 g/L monosaccharide with 0.10 g/L HMF was obtained from 10% (w/v)Kappaphycus alvareziiwith thermal acid hydrolysis using 350 mM HNO(3)at 121 degrees C for 60 min and enzymatic saccharification with a 1:1 mixture of Viscozyme L and Celluclast 1.5 L for 72 h. To enhance the galactose utilization rate, fermentation was performed with overexpression ofGAL1(galactokinase),GAL7(galactose-1-phosphate uridyltransferase),GAL10(UDP-glucose-4-epimerase), andPGM2(phosphoglucomutase 2) inSaccharomyces cerevisiaeCEN.PK2 usingCCW12as a strong promoter. Among the strains, the overexpression ofPGM2showed twofold high galactose utilization rate (URgal) and produced ethanol 1.4-fold more than that of the control. Transcriptional analysis revealed the increase ofPGM2transcription level leading to enhance glucose-6-phosphate and fructose-6-phosphate and plays a key role in ensuring a higher glycolytic flux in thePGM2strain. This finding shows particular importance in biofuel production from seaweed because galactose is one of the major monosaccharides in seaweeds such asK.alvarezii. | Sunwoo, In Yung; Sukwong, Pailin; Park, Yu Rim; Jeong, Deok Yeol; Kim, Soo Rin; Jeong, Gwi-Teak; Kim, Sung-Koo | Pukyong Natl Univ, Div Marine Fisheries & Life Sci, Busan 48513, South Korea; Umea Univ, Dept Chem, S-90187 Umea, Sweden; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea | ; Jeong, Deokyeol/GLR-8021-2022; Kim, Soo Rin/X-2192-2019 | 56506970700; 57195241085; 57216661150; 57191332457; 36659584200; 57222159868; 57195386876 | skkim@pknu.ac.kr; | APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY | APPL BIOCHEM BIOTECH | 0273-2289 | 1559-0291 | 193 | 2 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2021 | 3.094 | 63.8 | 0.59 | 2025-07-30 | 8 | 9 | Kappaphycus alvarezii; Fermentation; CRISPR; Cas9; PGM2; Ethanol | SACCHAROMYCES-CEREVISIAE; NITRIC-ACID; FERMENTATION; PHOSPHOGLUCOMUTASE; HYDROLYSIS; YEAST; GALACTOSE-1-PHOSPHATE; SACCHARIFICATION; PRETREATMENT; BIOETHANOL | CRISPR/Cas9; Ethanol; Fermentation; Kappaphycus alvarezii; PGM2 | Galactose; Gene Expression Regulation, Fungal; Plant Extracts; Rhodophyta; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Glucose; Nitric acid; Saccharification; Seaweed; Transcription; fructose 6 phosphate; galactokinase; galactose; galactose 1 phosphate uridylyltransferase; phosphoglucomutase; phosphoglucomutase 2; unclassified drug; uridine diphosphate glucose 4 epimerase; galactose; plant extract; Saccharomyces cerevisiae protein; Biofuel production; Enzymatic saccharification; Glucose 6 phosphates; Kappaphycus alvarezii; Phosphoglucomutase; Thermal acid hydrolysis; Transcription level; Transcriptional analysis; acid hydrolysis; Article; biofuel production; controlled study; CRISPR-CAS9 system; data analysis software; fermentation; gene overexpression; high performance liquid chromatography; Kappaphycus alvarezii; nonhuman; promoter region; protein expression; real time polymerase chain reaction; saccharification; Saccharomyces cerevisiae; signal transduction; transcription initiation; biosynthesis; chemistry; gene expression regulation; metabolism; red alga; Saccharomyces cerevisiae; Yeast | English | 2021 | 2021-02 | 10.1007/s12010-020-03422-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Enhancement of Galactose Uptake fromKappaphycus alvareziiUsingSaccharomyces cerevisiaethrough Deletion of Negative Regulators ofGALGenes | This study was aimed at enhancing galactose consumption from the red seaweedKappaphycus alvarezii.The optimal pretreatment condition of thermal acid hydrolysis was treated with 350 mM HNO(3)for 60 min at 121 degrees C. The enzymatic saccharification with a 1:1 mixture of Celluclast 1.5 L and Viscozyme L showed the maximum yield of glucose; 42-g/L monosaccharide concentration was obtained with the highest yield of pretreatment and enzymatic saccharification (E-PS) and the lowest inhibitory compound concentration. The deletion of theGAL80,MIG1,CYC8, orTUP1gene was performed to improve the galactose consumption rate. The strains with the deletion of theMIG1gene (mig1 Delta) showed higher galactose consumption rate and ethanol yield than other strains. High transcription levels of regulatory genes revealed that themig1 Delta relieved glucose repression. These results show that themig1 Delta enhances galactose consumption rate fromK. alvarezii. | Sunwoo, In Yung; Sukwong, Pailin; Park, Yu Rim; Jeong, Deok Yeol; Kim, Soo Rin; Jeong, Gwi-Teak; Kim, Sung-Koo | Pukyong Natl Univ, Dept Biotechnol, Busan 48513, South Korea; Umea Univ, Dept Chem, SE-90187 Umea, Sweden; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea | Jeong, Deokyeol/GLR-8021-2022; Kim, Soo Rin/X-2192-2019 | 56506970700; 57195241085; 57216661150; 57191332457; 36659584200; 57222159868; 57195386876 | skkim@pknu.ac.kr; | APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY | APPL BIOCHEM BIOTECH | 0273-2289 | 1559-0291 | 193 | 2 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2021 | 3.094 | 63.8 | 0.45 | 2025-07-30 | 7 | 7 | Kappaphycus alvarezii; Fermentation; CRISPR; Cas9; MIG1; Ethanol | SACCHAROMYCES-CEREVISIAE; RED SEAWEED; FERMENTATION; GENE; MIG1; IDENTIFICATION; ACTIVATION; GLUCOSE; BIOMASS; GAL80 | CRISPR/Cas9; Ethanol; Fermentation; Kappaphycus alvarezii; MIG1 | Galactose; Gene Deletion; Rhodophyta; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Glucose; Nitric acid; Saccharification; Yeast; alcohol; galactose; glucose; levulinic acid; monosaccharide; Saccharomyces cerevisiae protein; Enzymatic saccharification; Glucose repression; Inhibitory compounds; Kappaphycus alvarezii; Negative regulators; Pretreatment conditions; Thermal acid hydrolysis; Transcription level; acid hydrolysis; alcohol production; Article; chemical composition; colony polymerase chain reaction; controlled study; CRISPR-CAS9 system; cyc8 gene; data analysis software; DNA sequence; fermentation; gal80 gene; gene deletion; gene repression; genetic transcription; glucose intake; Kappaphycus alvarezii; mig1 gene; nonhuman; real time reverse transcription polymerase chain reaction; regulator gene; saccharification; Saccharomyces cerevisiae; seaweed; substrate concentration; tup1 gene; type strain; chemistry; genetics; metabolism; red alga; Transcription | English | 2021 | 2021-02 | 10.1007/s12010-020-03434-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Verification of Blood-Brain Barrier Disruption Based on the Clinical Validation Platform Using a Rat Model with Human Skull | Methods to improve drug delivery efficiency through blood-brain barrier disruption (BBBD) based on microbubbles and focused ultrasound (FUS) are continuously being studied. However, most studies are being conducted in preclinical trial environments using small animals. The use of the human skull shows differences between the clinical and preclinical trials. BBBD results from preclinical trials are difficult to represent in clinical trials because various distortions of ultrasound by the human skull are excluded in the former. Therefore, in our study, a clinical validation platform based on a preclinical trial environment, using a human skull fragment and a rat model, was developed to induce BBBD under conditions similar to clinical trials. For this, a human skull fragment was inserted between the rat head and a 250 kHz FUS transducer, and optimal ultrasound parameters for the free field (without human skull fragment) and human skull (with human skull fragment) were derived by 300 mV(pp) and 700 mV(pp), respectively. BBBD was analyzed according to each case using magnetic resonance images, Evans blue dye, cavitation, and histology. Although it was confirmed using magnetic resonance images and Evans blue dye that a BBB opening was induced in each case, multiple BBB openings were observed in the brain tissues. This phenomenon was analyzed by numerical simulation, and it was confirmed to be due to standing waves owing to the small skull size of the rat model. The stable cavitation doses (SCDh and SCDu) in the human skull decreased by 13.6- and 5.3-fold, respectively, compared to those in the free field. Additionally, the inertial cavitation dose in the human skull decreased by 1.05-fold compared to that of the free field. For the histological analysis, although some extravasated red blood cells were observed in each case, it was evaluated as recoverable based on our previous study results. Therefore, our proposed platform can help deduct optimal ultrasound parameters and BBBD results for clinical trials in the preclinical trials with small animals because it considers variables relevant to the human skull. | Park, Chan Yuk; Seo, Hyeon; Lee, Eun-Hee; Han, Mun; Choi, Hyojin; Park, Ki-Su; Yoon, Sang-Youl; Chang, Sung Hyun; Park, Juyoung | Daegu Gyeongbuk Med Innovat Fdn, Med Device Dev Ctr, Daegu 41061, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurosurg, Daegu 41944, South Korea; Gachon Univ, Coll Future Ind, Dept High Tech Med Device, Seongnam Si 13120, South Korea | 56963014800; 55516715100; 57212665883; 55671172700; 57193758792; 55932363100; 57195615457; 57753019200; 55329181100 | tanya00@naver.com;hseo0612@dgmif.re.kr;ehlee@dgmif.re.kr;munhan@dgmif.re.kr;chn21jin@gmail.com;kiss798@gmail.com;customplus@naver.com;feeling1398@gmail.com;opedoors@gmail.com; | BRAIN SCIENCES | BRAIN SCI | 2076-3425 | 11 | 11 | SCIE | NEUROSCIENCES | 2021 | 3.333 | 63.8 | 0.34 | 2025-07-30 | 6 | 5 | focused ultrasound; blood-brain barrier; acoustic cavitation; ultrasound field simulation | GENE DELIVERY; ULTRASOUND; DRUG; NEUROTOXICITY; PROPAGATION; CAVITATION; ABSORPTION; THERAPY; SYSTEM | Acoustic cavitation; Blood-brain barrier; Focused ultrasound; Ultrasound field simulation | adult; animal experiment; animal model; animal tissue; Article; blood brain barrier; brain hemorrhage; brain tissue; computer assisted tomography; computer simulation; controlled study; craniotomy; diffusion weighted imaging; drug delivery system; extracellular matrix; focused ultrasound therapy; food frequency questionnaire; histology; histopathology; hydrodistillation; intracranial pressure; male; molecular dynamics; nonhuman; nuclear magnetic resonance; nuclear magnetic resonance imaging; optical coherence tomography angiography; rat; simulation; skull; surface property | English | 2021 | 2021-11 | 10.3390/brainsci11111429 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Original Articles Preoperative Hematological Parameters for Predicting Ovarian Torsion in Patients with Mature Cystic Teratoma | Objective: The objective of this study is to evaluate the preoperative hematological parameters to predict ovarian torsion in patients with ovarian mature cystic teratoma. We also analyzed the diagnostic value of these makers to predict ovarian necrosis in cases of torsion as well as the effect of torsion on ovarian reserve. Patients and Methods: This is a retrospective study of 132 patients who received either laparoscopic or laparotomy surgery for OMCT at a single university hospital. Clinical characteristics and preoperative hematological parameters were compared between patients with or without torsion. Patients with torsion were further classified as infarction and non-infarction group. Preoperative parameters were compared between the two groups as well. Results: White blood cell (WBC) count, neutrophil percent, neutrophil count, and neutrophil to lymphocyte ratio (NLR) were higher in the torsion group (n=37) than the non-torsion group (n=95) (p<0.05 for all). Although statistically insignificant, the preoperative anti-Mullerian hormone (AMH) was lower in the torsion group than the non-torsion group (4.07 +/- 3.38 vs 6.1 +/- 3.6, p=0.122). In cases of torsion, the infarction group showed higher WBC count and lymphocyte count but lower hemoglobin level and platelet to lymphocyte ratio (PLR) than the non-infarction group (p<0.05 for all). Conclusion: The WBC count, neutrophil percent, neutrophil count, and NLR were higher in the cases of OMCT with torsion, and these parameters may be useful to diagnose OMCT with torsion. Also, adnexal torsion may deteriorate ovarian reserved as indicated by decreased AMH in torsion group. | Lee, Jisun; Park, Jinyoung; Lee, Hyun Jung; Kim, Mi Ju; Lee, Yoon Hee; Chong, Gun Oh; Hong, Dae Gy; Lee, Taek Hoo | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Obstet & Gynecol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Obstet & Gynecol, Daegu, South Korea | Kim, Mi Ju/HGU-8470-2022; PARK, JUN-YOUNG/P-5981-2015 | 57216463710; 57190865032; 57202930844; 55908927600; 37088851700; 23099068000; 26656670100; 56122334300 | thlee@knu.ac.kr; | INTERNATIONAL JOURNAL OF WOMENS HEALTH | INT J WOMENS HEALTH | 1179-1411 | 13 | SCIE | OBSTETRICS & GYNECOLOGY | 2021 | 2.59 | 64.1 | 0.54 | 2025-07-30 | 6 | 6 | leukocyte counts; necrosis; ovarian neoplasm; ovarian teratoma; ovarian reserve; torsion | LYMPHOCYTE RATIO; NEUTROPHIL; REPERFUSION; MANAGEMENT; DIAGNOSIS; ISCHEMIA; CT | Leukocyte counts; Necrosis; Ovarian neoplasm; Ovarian reserve; Ovarian teratoma; Torsion | CA 125 antigen; CA 19-9 antigen; hemoglobin; Muellerian inhibiting factor; adult; Article; clinical feature; controlled study; cystectomy; diagnostic value; female; hematological parameters; hemoglobin blood level; human; human cell; laparoscopic surgery; laparotomy; leukocyte count; lymphocyte count; lymphocyte monocyte ratio; major clinical study; mature teratoma; mean corpuscular volume; mean platelet volume; neutrophil count; neutrophil lymphocyte ratio; ovarian reserve; ovariectomy; ovary torsion; platelet count; platelet lymphocyte ratio; preoperative evaluation; red blood cell distribution width; retrospective study; university hospital; x-ray computed tomography | English | 2021 | 2021 | 10.2147/ijwh.s285335 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Behavioral changes after hospital discharge in preschool children experiencing emergence delirium after general anesthesia: A prospective observational study | Background Emergence delirium is well known as early postoperative behavioral change after general anesthesia. However, it is unclear whether children with emergence delirium have negative behavioral changes after hospital discharge. Aim This observational study investigated the association between emergence delirium and posthospital behavioral changes. Methods One-hundred preschoolers aged 2-7 years undergoing elective surgery were enrolled in 2 tertiary university hospitals. Preoperative anxiety level was assessed using modified Yale preoperative anxiety scale. Emergence delirium was defined via pediatric anesthesia emergence delirium score >= 12 at any time in the recovery room. We divided the delirium score into a delirium-specific score (the sum of the first 3 items: eye contact, purposeful movement, and awareness of surrounding) and a pain-related score (the sum of the last 2 items: restlessness and inconsolability). High delirium scores represent severe emergence delirium. Posthospital behavioral changes were assessed by a change in Child Behavior Checklist 1.5-5 scores before and 1 week after surgery. The primary outcome was the total behavior checklist scores 1 week after surgery. Multiple linear regression was performed to identify risk factors for posthospital behavioral changes. Results Children with emergence delirium (n = 58) had higher postoperative behavior checklist scores than children without emergence delirium (n = 42) [mean (SD), 22.8 (17.5) vs. 14.0 (12.1); mean difference (95% CI), 8.8 (1.5-16.2)]. Increases in preoperative anxiety level [regression coefficient (b) (95% CI) =0.241 (0.126-0.356)] and peak delirium-specific score [b = 0.789 (0.137-1.442)] were associated with an increase in behavior checklist score 1 week after surgery, while pain-related score, type of surgery, premedication, and age were not. Conclusion Children with emergence delirium developed more severe behavior changes 1 week after surgery than those without emergence delirium. High preoperative anxiety level and emergence delirium scores were associated with posthospital behavioral changes. | Kim, Jonghae; Byun, Sung Hye; Kim, Jun Won; Kim, Ji-Yoon; Kim, Yun Jin; Choi, Nayeon; Lee, Bong Soo; Yu, Seungcheol; Kim, Eugene | Daegu Catholic Univ, Sch Med, Med Ctr, Dept Anesthesiol & Pain Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Anesthesiol & Pain Med, Daegu, South Korea; Catholic Univ Daegu, Sch Med, Dept Psychiat, Daegu, South Korea; Hanyang Univ, Med Ctr, Dept Anesthesiol & Pain Med, Seoul, South Korea; Hanyang Univ, Med Res Collaborating Ctr, Biostat Consulting & Res Lab, Seoul, South Korea; Hanyang Univ, Med Ctr, Coll Med, Dept Anesthesiol & Pain Med, 222 Wangsimni Ro, Seoul 04763, South Korea | Kim, Eugene/E-2446-2019; Kim, Jae-Hong/B-2530-2009; Kim, Byung-Hak/AAY-9891-2020; Kim, JongHae/HGC-1554-2022; Byun, Sung Hye/AEK-1234-2022 | 57865562800; 56921446300; 57191681410; 55862653200; 58741721000; 57216808932; 57223629729; 57226542073; 57203552434 | tomomie@hanmail.net; | PEDIATRIC ANESTHESIA | PEDIATR ANESTH | 1155-5645 | 1460-9592 | 31 | 10 | SCIE | ANESTHESIOLOGY;PEDIATRICS | 2021 | 2.129 | 64.2 | 3.07 | 2025-07-30 | 25 | 25 | child behavior checklist; emergence delirium; general anesthesia; posthospital change; preoperative anxiety; preschool children | PREOPERATIVE ANXIETY; PEDIATRIC-PATIENTS; CHECKLIST; AGITATION; SEVOFLURANE; COHORT; PAIN | child behavior checklist; emergence delirium; general anesthesia; posthospital change; preoperative anxiety; preschool children | Anesthesia Recovery Period; Anesthesia, General; Child; Child, Preschool; Emergence Delirium; Hospitals; Humans; Patient Discharge; anxiety assessment; anxiety disorder; Article; behavior change; child; child behavior; Child Behavior Checklist; controlled study; elective surgery; emergence agitation; female; general anesthesia; hospital discharge; human; major clinical study; male; modified Yale preoperative anxiety scale; observational study; pediatric anesthesia; Pediatric Anesthesia Emergence Delirium; preschool child; prospective study; adverse event; anesthetic recovery; emergence agitation; general anesthesia; hospital; hospital discharge | English | 2021 | 2021-10 | 10.1111/pan.14259 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Anomalous hyperplastic anterior choroidal artery and its mimicker: a case series | The anomalous hyperplastic anterior choroidal artery (AchoA) is a rare anomaly due to incomplete distal annexation between the primitive AchoA and posterior cerebral artery (PCA). It is often misdiagnosed or misunderstood as a duplicated or fetal type PCA because of its supply distribution. In addition, its aneurysm incidence is much higher than the overall aneurysm incidence of AchoA. Thus, endovascular procedures or surgery without comprehensive understanding of this anomaly can cause critical complications. Herein, we present a case series of anomalous hyperplastic AchoA and its mimicker, along with schematic images for comprehensive understanding. | Hahm, Myong Hun; Moon, Sungjun | Kyungpook Natl Univ, Sch Med, Dept Radiol, 130 Dongdeok Ro, Daegu 41944, South Korea; Yeungnam Univ, Dept Radiol, Coll Med, 170 Hyeonchung Ro, Daegu 42415, South Korea | 56015548700; 57189891980 | sjmoon@yu.ac.kr; | SURGICAL AND RADIOLOGIC ANATOMY | SURG RADIOL ANAT | 0930-1038 | 1279-8517 | 43 | 12 | SCIE | ANATOMY & MORPHOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING;SURGERY | 2021 | 1.354 | 64.3 | 1.2 | 2025-07-30 | 6 | 8 | Anterior choroidal artery; Posterior cerebral artery; Anomaly; Hyperplasia; Duplication; MR imaging | Anomaly; Anterior choroidal artery; Duplication; Hyperplasia; MR imaging; Posterior cerebral artery | Carotid Artery, Internal; Cerebral Angiography; Cerebral Arteries; Humans; Hyperplasia; Intracranial Aneurysm; Posterior Cerebral Artery; adult; aged; anomalous hyperplastic anterior choroidal artery; arteriovenous malformation; Article; carotid arteriography; case report; case study; cerebellum infarction; child; choroid disease; clinical article; coil embolization; dysarthria; endovascular surgery; female; human; hyperplasia; magnetic resonance angiography; male; middle aged; neuroimaging; nuclear magnetic resonance imaging; posterior cerebral artery; preschool child; rare disease; seizure; stereotactic radiosurgery; T2 weighted imaging; temporal lobe; very elderly; brain angiography; brain artery; hyperplasia; internal carotid artery; intracranial aneurysm; pathology | English | 2021 | 2021-12 | 10.1007/s00276-021-02777-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Comparison of the insertion patterns of the extensor hallucis longus muscle in Korean focusing on the regional difference | Purpose From the evolutionary myology, the additional tendon of the extensor hallucis longus (EHL) muscle represents the sample of a new acquisition. We aimed to determine whether the insertion pattern of the EHL muscle differs in Koreans according to demographic populations, especially between Jeju islanders and the Korean Peninsula inhabitants. Methods We used 69 Korean cadavers and classified the tendinous insertion of the EHL muscle as Pattern I, Pattern II, and Pattern III. The ratio of each Pattern in adult cadaveric samples was compared between demographic populations. Results The proportion of Pattern I, Pattern II, and Pattern III of the EHL muscle was 30.43, 63.77, and 5.80%, respectively, further divided into 18.00 vs. 36.04%, 72.00 vs. 60.47%, 10.00 vs. 3.49% in Jeju islanders vs. peninsular Koreans. There was a considerable difference in the insertion patterns of the EHL muscle in each regional group (p = 0.032), but not in each gender, age, and body sides of lower limbs. Conclusion The findings of this study indicate that there was a higher incidence of the accessory tendon(s) of the EHL muscle in Koreans and the distributed insertion patterns of the EHL muscle was significantly different between Jeju islanders and peninsular Koreans. | Chang, Inyoub; Na, Euihyeon; Oh, Ji Won; Kim, Jinu; Yoon, Sang-Pil | Chosun Univ, Coll Med, Dept Anat, Gwangju 61452, South Korea; Presbyterian Med Ctr, Dept Neuropsychiat, Jeonju 54987, South Korea; Kyungpook Natl Univ, Sch Med, Dept Anat, Daegu 41944, South Korea; Jeju Natl Univ, Sch Med, Dept Anat, 102 Jejudaehak Ro, Jeju Si 63243, Jeju Do, South Korea | Oh, Ji/AAZ-3153-2020 | 7201742338; 57193707538; 36093206200; 16316045800; 11939485000 | spyoon@jejunu.ac.kr; | SURGICAL AND RADIOLOGIC ANATOMY | SURG RADIOL ANAT | 0930-1038 | 1279-8517 | 43 | 7 | SCIE | ANATOMY & MORPHOLOGY;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING;SURGERY | 2021 | 1.354 | 64.3 | 0 | 2025-07-30 | 0 | 0 | Extensor halluces longus; Insertion; Jeju island; Korean | Extensor halluces longus; Insertion; Jeju island; Korean | Adolescent; Adult; Aged; Aged, 80 and over; Anatomic Variation; Cadaver; Dissection; Female; Geography; Hallux; Humans; Male; Middle Aged; Muscle, Skeletal; Republic of Korea; Tendons; Young Adult; adult; article; cadaver; demography; female; gender; human; incidence; Korean (people); lower limb; male; tendon; adolescent; aged; anatomical variation; anatomy and histology; comparative study; dissection; geography; hallux; middle aged; skeletal muscle; South Korea; tendon; very elderly; young adult | English | 2021 | 2021-07 | 10.1007/s00276-021-02702-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Contribution of SOS genes to H2O2-induced apoptosis-like death in Escherichia coli | Hydrogen peroxide (H2O2) is a debriding agent that damages the microbial structure and function by generating various reactive oxygen species (ROS). H2O2-produced hydroxyl radical (OH center dot) also exerts oxidative stress on microorganisms. The spread of antibiotic-resistance in bacteria is a serious issue worldwide, and greater efforts are needed to identify and characterize novel antibacterial mechanisms to develop new treatment strategies. Therefore, this study aimed to clarify the relationship between H2O2 and Escherichia coli and to elucidate a novel antibacterial mechanism(s) of H2O2. Following H2O2 exposure, increased levels of 8-hydroxydeoxyguanosine and malondialdehyde indicated that H2O2 accelerates oxidation of bacterial DNA and lipids in E. coli. As oxidative damage worsened, the SOS response was triggered. Cell division arrest and resulting filamentous cells were identified in cells, indicating that LexA was involved in DNA replication. It was also verified that RecA, a representative SOS gene, helps self-cleavage of LexA and acts as a bacterial caspase-like protein. Our findings also showed that dinF is essential to preserve E. coli from H2O2-induced ROS, and furthermore, demonstrated that H2O2-induced SOS response and SOS genes participate differently in guarding E. coli from oxidative stress. As an extreme SOS response is considered apoptosis-like death (ALD) in bacteria, additional experiments were performed to examine the characteristics of ALD. DNA fragmentation and membrane depolarization appeared in H2O2-treated cells, suggesting that H2O2 causes ALD in E. coli. In conclusion, our investigations revealed that ALD is a novel antibacterial mode of action(s) of H2O2 with important contributions from SOS genes. | Kim, Heesu; Lee, Dong Gun | Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea | ; Lee, Dong-Gun/IWD-9833-2023 | 57219859173; 55668060900 | dglee222@knu.ac.kr; | CURRENT GENETICS | CURR GENET | 0172-8083 | 1432-0983 | 67 | 6 | SCIE | GENETICS & HEREDITY | 2021 | 2.695 | 64.3 | 0.73 | 2025-07-30 | 12 | 13 | Hydrogen peroxide; Escherichia coli; SOS response; Apoptosis-like death; Reactive oxygen species | PROGRAMMED CELL-DEATH; OXYGEN SPECIES ROS; HYDROGEN-PEROXIDE; OXIDATIVE STRESS; DNA-DAMAGE; MECHANISMS; MEMBRANE; PHOSPHATIDYLSERINE; DEPLETION; EXPOSURE | Apoptosis-like death; Escherichia coli; Hydrogen peroxide; Reactive oxygen species; SOS response | Apoptosis; DNA Fragmentation; Escherichia coli; Escherichia coli Infections; Gene Expression Regulation, Bacterial; Hydrogen Peroxide; Hydroxyl Radical; Intracellular Space; Lipid Peroxidation; Oxidative Stress; Reactive Oxygen Species; Rec A Recombinases; SOS Response, Genetics; 8 hydroxydeoxyguanosine; bacterial DNA; caspase; hydrogen peroxide; lipid; malonaldehyde; reactive oxygen metabolite; SOS protein; hydrogen peroxide; hydroxyl radical; reactive oxygen metabolite; RecA protein; apoptosis; Article; cell division; controlled study; DNA fragmentation; DNA replication; Escherichia coli; in vitro study; membrane depolarization; nonhuman; oxidation; oxidative stress; sos response (genetics); apoptosis; Escherichia coli; Escherichia coli infection; gene expression regulation; genetics; intracellular space; lipid peroxidation; metabolism; microbiology; physiology | English | 2021 | 2021-12 | 10.1007/s00294-021-01204-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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