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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Ultraviolet Radiation-Emitting Gd³⁺-Doped Sr2ZnSi2O7 Host Lattice Prepared by Sol-Gel Procedure and Evaluation of Gamma-Ray Exposure Parameters | Using the sol-gel process, a series of Sr2-xZnSi2O7:xGd (0.01 S-8(7/2)) in all the samples. The electron paramagnetic resonance (EPR) and PL analyses confirmed the presence of Gd3+ in the Sr2ZnSi2O7 structure, where the Gd3+ ions occupied distorted Sr2+ sites in the host lattice. Additionally, three photon interaction parameters, namely the mass attenuation coefficient, effective atomic number, and effective electron density, were calculated within the 1 keV-100 GeV photon energy range for all the samples. These photon interaction parameters varied widely over the studied energy range. Particularly, the shielding effectiveness increased with increasing gadolinium concentration. These interaction parameters will be very useful for shielding applications against gamma-rays. | Singh, Vijay; Singh, N.; Natarajan, V; Singh, V. P.; Lakshminarayana, G. | Konkuk Univ, Dept Chem Engn, Seoul 05029, South Korea; Inst Adv Res, Gandhinagar 382007, Gujarat, India; Karnatak Univ, Dept Phys, Dharwad, Karnataka, India; Kyungpook Natl Univ, Intelligent Construct Automat Ctr, 80 Daehak Ro, Daegu 41566, South Korea | 57205227140; 57202910594; 7102571622; 36841344800; 57194637883 | vijayjiin2006@yahoo.com; | JOURNAL OF ELECTRONIC MATERIALS | J ELECTRON MATER | 0361-5235 | 1543-186X | 50 | 1 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;MATERIALS SCIENCE, MULTIDISCIPLINARY;PHYSICS, APPLIED | 2021 | 2.047 | 62.1 | 0 | 2025-07-30 | 0 | 0 | Ultraviolet radiation; sol– gel; EPR; Gd3+; Sr2ZnSi2O7; gamma-ray shielding | NARROW-BAND UVB; LUMINESCENT PROPERTIES; DIELECTRIC-PROPERTIES; SHIELDING PROPERTIES; PHOSPHOR; PHOTOLUMINESCENCE; RESONANCE; GLASSES; DY3+; GD3+ | EPR; gamma-ray shielding; Gd<sup>3+</sup>; sol–gel; Sr<sub>2</sub>ZnSi<sub>2</sub>O<sub>7</sub>; Ultraviolet radiation | Atoms; Electron spin resonance spectroscopy; Gadolinium compounds; Multiphoton processes; Paramagnetic resonance; Photoluminescence spectroscopy; Photons; Scanning electron microscopy; Shielding; Silicon; Silicon compounds; Sols; Strontium compounds; X ray powder diffraction; Zinc compounds; Crystal characteristics; Effective atomic number; Effective electron densities; Electron paramagnetic resonances (EPR); Interaction parameters; Mass attenuation coefficients; Shielding effectiveness; Spectral characteristics; Gamma rays | English | 2021 | 2021-01 | 10.1007/s11664-020-08549-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Gomisin M2 alleviates psoriasis-like skin inflammation by inhibiting inflammatory signaling pathways | Psoriasis, a chronic inflammatory skin disease, is characterized by the excessive proliferation and impaired differentiation of epidermal keratinocytes and is accompanied by the increased infiltration of inflammatory cells. The condition requires long-term treatment and has no definitive cure. Hence, supplements and therapeutic agents have been intensely investigated. Gomisin M2 (GM2), a lignan extracted from Schisandra chinensis (Turcz). Baill. (Schisandraceae; S. chinensis), has demonstrated diverse pharmacological properties, including anticancer, anti-inflammatory and antiallergic effects. Based on these findings, the present study examined the effects of GM2 on an imiquimod (IMQ)-induced psoriasis mouse model and on keratinocytes stimulated by tumor necrosis factor (TNF)-alpha and interferon-gamma. IMQ was topically applied to the back skin of mice for 7 consecutive days, and the mice were orally administered CD. These results showed that the oral administration of GM2 suppressed the symptoms of psoriasis, as evidenced by reductions in skin thickness, psoriasis area severity index scores for psoriasis lesions, transepidermal water loss and myeloperoxidase (MPO)-associated cell infiltration. Furthermore, GM2 reduced the pathologically increased levels of immunoglobulin G2a, MPO and TNF-alpha in the serum and T helper (Th)1 and Th17 cell populations in the spleen. GM2 decreased the gene expression of inflammatory-related cytokines and chemokines and inhibited the expression of signal transducer and activator of transcription 1 and nuclear factor-kappa B in the activated keratinocytes. These results suggested that GM2 from S. chinensis is a potential therapeutic candidate to alleviate psoriasis-like skin inflammation. | Kim, Namkyung; Lee, Soyoung; Kang, Jinjoo; Kwon, Taeg Kyu; Khang, Dongwoo; Kim, Sang-Hyun | Kyungpook Natl Univ, Sch Med, Dept Pharmacol, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Korea Res Inst Biosci & Biotechnol, Immunoregulatory Mat Res Ctr, Jeongeup 56212, Jeollabuk Do, South Korea; Keimyung Univ, Sch Med, Dept Immunol, Daegu 42601, South Korea; Gachon Univ, Sch Med, Dept Physiol, 155 Gaetbeol Ro, Incheon 21999, South Korea | 57216981866; 8537269200; 57216977823; 7202206057; 26039177500; 57210450420 | dkhang@gachon.ac.kr;shkim72@knu.ac.kr; | MOLECULAR MEDICINE REPORTS | MOL MED REP | 1791-2997 | 1791-3004 | 24 | 6 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL;ONCOLOGY | 2021 | 3.423 | 62.2 | 0.35 | 2025-07-30 | 5 | 6 | gomisin M2; psoriasis; keratinocytes; myeloperoxidase; Th1; Th17 cells | SCHISANDRA; PATHOGENESIS; EXPRESSION; LIGNANS; MICE | Gomisin M2; Keratinocytes; Myeloperoxidase; Psoriasis; Th1/Th17 cells | Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Imiquimod; Inflammation; Interferon-gamma; Keratinocytes; Mice, Inbred C57BL; NF-kappa B; Psoriasis; Signal Transduction; STAT1 Transcription Factor; Th1 Cells; Th17 Cells; Tumor Necrosis Factor-alpha; CXCL1 chemokine; dexamethasone; gamma interferon; gomisin; immunoglobulin enhancer binding protein; immunoglobulin G2a; interleukin 17; interleukin 1beta; interleukin 23; interleukin 6; interleukin 8; myeloperoxidase; STAT1 protein; tumor necrosis factor; antiinflammatory agent; cytokine; gamma interferon; herbaceous agent; imiquimod; immunoglobulin enhancer binding protein; STAT1 protein; STAT1 protein, human; tumor necrosis factor; animal experiment; animal model; animal tissue; antiallergic activity; antiinflammatory activity; antineoplastic activity; Article; cell viability; column chromatography; controlled study; dermatitis; female; gene expression level; HaCat cell line; histology; human; human cell; immunohistochemistry; isolation procedure; keratinocyte; laminar airflow; liquid chromatography; mouse; nonhuman; psoriasis; Psoriasis Area and Severity Index; real time polymerase chain reaction; room temperature; Schisandra chinensis; signal transduction; skin water loss; skinfold thickness; TH1 cell line; Th17 cell; animal; C57BL mouse; cell line; disease model; drug effect; genetics; inflammation; metabolism; pathology; psoriasis; Th1 cell | English | 2021 | 2021-12 | 10.3892/mmr.2021.12499 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical outcomes and healthcare costs of inpatients with tetanus in Korea, 2011-2019 | BackgroundTetanus is a rare, vaccine-preventable but extremely serious disease. We investigated the recent trend of the clinical outcomes and medical costs for inpatients with tetanus in South Korea over 10years.MethodsWe conducted a retrospective review to determine the clinical factors and medical costs associated with tetanus at two national university hospitals in South Korea between January 2011 and October 2019.ResultsForty-nine patients were admitted for tetanus (mean age, 67.0years [range, 53.0-80.0years]; 32 women [57.1%]). All the patients had generalized tetanus, and 5 (10.2%) died during hospitalization. The median duration from symptom onset to hospital admission was 4days. Trismus (85.7%) was the most common symptom, and the median hospital stay was 39days. Thirty-two patients (65.3%) required mechanical ventilation, and 20 (40.8%) developed aspiration pneumonia. The median total healthcare cost per patient was US $18,011. After discharge, 35 patients (71.4%) recovered sufficiently to walk without disability.ConclusionsTetanus requires long hospital stays and high medical expenditures in South Korea; however, the vaccination completion rate is low. Medical staff should therefore promote medical advice and policies on the management of tetanus to the general South Korean population. | Bae, Sohyun; Go, Minsik; Kim, Yoonjung; Hwang, Soyoon; Kim, Shin-Woo; Kwon, Ki Tae; Jung, Sook-In; Chang, Hyun-Ha | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Infect Dis, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Chonnam Natl Univ, Med Sch, Dept Infect Dis, 42 Jebongro, Gwangju 61469, South Korea | Hwang, Soyoon/HHM-5762-2022; JUNG, SOOK IN/AGO-2862-2022; Kim, Hanjin/KYP-2633-2024; Kim, Tae-You/J-2750-2012; Kim, Sooyeon/AAA-8521-2022 | 57219699506; 57222337491; 57203160508; 57203160675; 8710731500; 9733850500; 7403676835; 7407521688 | sijung@chonnam.ac.kr;changhua@knu.ac.kr;changhha@knu.ac.kr; | BMC INFECTIOUS DISEASES | BMC INFECT DIS | 1471-2334 | 21 | 1 | SCIE | INFECTIOUS DISEASES | 2021 | 3.669 | 62.6 | 0.49 | 2025-07-30 | 9 | 8 | Tetanus; Healthcare costs; Treatment outcome | SOUTHERN VIETNAM; DIPHTHERIA; IMMUNIZATION; VACCINATION; AWARENESS; PROGRAM | Healthcare costs; Tetanus; Treatment outcome | Aged; Aged, 80 and over; Female; Health Care Costs; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Pneumonia, Aspiration; Republic of Korea; Respiration, Artificial; Retrospective Studies; Tetanus; Treatment Outcome; tetanus toxoid; adult; aged; Article; artificial ventilation; aspiration pneumonia; atrial fibrillation; autonomic dysfunction; blood examination; brain infarction; clinical article; clinical outcome; cohort analysis; controlled study; dysarthria; dysphagia; dyspnea; female; fever; health care cost; hospital admission; hospital discharge; hospital infection; hospital patient; hospitalization; human; hypersalivation; lung embolism; male; mobilization; mortality; muscle rigidity; nausea and vomiting; opisthotonus; patient care; radiology; rehabilitation care; respiratory failure; resuscitation; retrospective study; seizure; South Korea; tetanus; tracheostomy; trend study; trismus; university hospital; urinary tract infection; vaccination; ventilator associated pneumonia; aspiration pneumonia; complication; economics; length of stay; middle aged; pathology; tetanus; treatment outcome; very elderly | English | 2021 | 2021-03-09 | 10.1186/s12879-021-05935-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Prognostic Value of Lymph Node Characteristics in Patients with Cervical Cancer Treated with Radical Hysterectomy | Objective: This study evaluated the prognostic value of various lymph node (LN) characteristics, including the lymph node ratio (LNR), in patients with cervical cancer treated with radical hysterectomy. Methods: In this retrospective study, 260 patients with cervical cancer who had undergone radical hysterectomy with pelvic or paraaortic lymphadenectomies were included. LN characteristics related to several LN statuses included total LN counts, LN metastasis, total positive LN counts, LNR, and levels of lymphadenectomy. LNR was defined as the number of metastatic LNs divided by the total number of LNs harvested. Univariate and multivariate analyses for disease-free survival (DFS) and overall survival (OS) were performed using the clinicopathological and LN characteristics. Results: Based on receiver-operating characteristics curve analysis, the cut-off value of LNR was 0.0625. Multivariate analysis revealed that high LNR was significantly related to tumor recurrence (hazard ratio [HR], 5.182; 95% confidence interval [CI], 2.424-11.075; p < 0.0001). After adjusting for clinicopathological factors, LNR was also independent prognostic factor for predicting tumor recurrence (HR, 5.930; 95% CI, 2.114-16.634; p = 0.0007). However, total retrieved LN counts and level of lymphadenectomy were not associated with survival outcomes. Conclusion: LNR may be a prognostic biomarker for predicting disease recurrence in cervical cancer treated with radical hysterectomy. | Lee, Yoon Hee; Chong, Gun Oh; Kim, Su Jeong; Hwang, Ja Hyun; Kim, Jong Mi; Park, Nora Jee-Young; Hong, Dae Gy | Kyungpook Natl Univ, Sch Med, Dept Obstet & Gynecol, Daegu, South Korea; Kyungpook Natl Univ, Dept Obstet & Gynecol, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Clin Omics Res Ctr, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pathol, Daegu, South Korea | 37088851700; 23099068000; 36666447400; 57218568938; 57212764251; 57226185359; 26656670100 | gochong@knu.ac.kr; | CANCER MANAGEMENT AND RESEARCH | CANCER MANAG RES | 1179-1322 | 13 | SCIE | ONCOLOGY | 2021 | 3.602 | 62.7 | 0.55 | 2025-07-30 | 8 | 9 | cervical cancer; lymph node ratio; radical hysterectomy; prognosis | PELVIC RADIATION-THERAPY; STAGE IB; CARCINOMA; LYMPHADENECTOMY; NUMBER; IIA | Cervical cancer; Lymph node ratio; Prognosis; Radical hysterectomy | adult; Article; cancer prognosis; cancer recurrence; controlled study; disease free survival; female; human; human tissue; lymph node dissection; lymph node metastasis; lymph node ratio; major clinical study; middle aged; overall survival; paraaortic lymphadenectomy; pathology; pelvis lymphadenectomy; prediction; radical hysterectomy; retrospective study; tumor recurrence; uterine cervix cancer | English | 2021 | 2021 | 10.2147/cmar.s332612 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Genetic polymorphism of vir genes of Plasmodium vivax in Myanmar | The Plasmodium vivax variant proteins encoded by vir genes are highly polymorphic antigens and are considered as one of key proteins of P. vivax for host immune evasion via antigenic variations. Because genetic diversity of these antigens is a critical hurdle in the development of an effective vaccine, understanding the genetic nature of the vir genes in natural population is important. In this study, we selected four vir genes (vir 4, vir 12, vir 21, and vir 27) previously used for genetic analysis in several studies and evaluated the genetic polymorphisms and phylogenetic relationship of these 4 vir genes in Myanmar P. vivax population. Taken all genetic diversity values, the vir 12 (S = 168, H = 17, Hd = 0.854, Tajima's D value = 2.91524) was the most genetically diverse gene and the vir 4 (S = 9, H = 4, Hd = 0.744, Tajima's D value = -0.49151) was the most conserved gene. All phylogenetic trees showed two clades, and vir 4 and 12 haplotypes from Myanmar were clustered in a distinct clade with those from India and Republic of Korea. These results confirmed the pattern of high genetic polymorphism of vir genes and provided information on vir gene for further functional research and studies focused toward the practical use of vir genes. | Na, Byoung-Kuk; Kim, Tong-Soo; Lin, Khin; Baek, Moon-Chang; Chung, Dong-Il; Hong, Yeonchul; Goo, Youn-Kyoung | Gyeongsang Natl Univ, Coll Med, Inst Hlth Sci, Dept Parasitol & Trop Med, Jinju 52727, South Korea; Inha Univ, Coll Med, Inha Res Inst Med Sci, Dept Trop Med, Incheon 22212, South Korea; Pyin Oo Lwin Branch, Dept Med Res, Pyin Oo Lwin, Myanmar; Kyungpook Natl Univ, Sch Med, Dept Mol Med, CMRI, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Parasitol & Trop Med, Daegu 41944, South Korea | Na, b/KPY-6354-2024 | 7005291099; 7407121005; 7403967071; 7006013097; 13310373300; 7403392847; 22937863200 | kuku1819@knu.ac.kr; | PARASITOLOGY INTERNATIONAL | PARASITOL INT | 1383-5769 | 1873-0329 | 80 | SCIE | PARASITOLOGY | 2021 | 2.106 | 62.8 | 0.3 | 2025-07-30 | 4 | 4 | Plasmodium vivax; Myanmar; vir gene; Genetic diversity | Genetic diversity; Myanmar; Plasmodium vivax; vir gene | Genes, Protozoan; Myanmar; Plasmodium vivax; Polymorphism, Genetic; Protozoan Proteins; protozoal protein; article; cladistics; controlled study; genetic analysis; genetic association; genetic polymorphism; genetic variability; haplotype; India; Myanmar; nonhuman; phylogenetic tree; Plasmodium vivax; South Korea; gene; genetics; metabolism; Myanmar; Plasmodium vivax | English | 2021 | 2021-02 | 10.1016/j.parint.2020.102233 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Oncologic Outcomes of Intracorporeal vs Extracorporeal Urinary Diversion After Robot-Assisted Radical Cystectomy: A Multi-Institutional Korean Study | Background: We aimed to compare the oncologic outcomes of intracorporeal urinary diversion (ICUD) and extracorporeal urinary diversion (ECUD) following robot-assisted radical cystectomy (RARC) in patients diagnosed with bladder cancer. Materials and Methods: Medical records of 730 patients who underwent RARC between April 2007 and May 2019 in 11 tertiary referral centers were retrospectively reviewed. We assessed recurrence-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS) in the two groups using the Kaplan-Meier method. Cox regression models were used to identify factors associated with RFS, CSS, and OS. Results: Among 591 patients, neobladder diversion was performed more frequently in the ICUD group (70.8% vs 52.5%, p = 0.001). The median follow-up duration was shorter in the ICUD group than in the ECUD group (16 vs 26 months, p < 0.001). The rates of overall recurrence (36.5% vs 25.5%, p = 0.013) and pelvic recurrence (12.1% vs 5.9%, p = 0.031) were higher in the ECUD group. However, no differences in 5-year RFS (43.2% vs 58.4%, p = 0.516), CSS (79.3% vs 89.7%, p = 0.392), and OS (74.3% vs 81.4%, p = 0.411) were noted between the two groups. Multivariable analysis revealed that when compared to ICUD, ECUD was not associated with RFS (hazard ratio [HR], 0.982; p = 0.920), CSS (HR, 0.568; p = 0.126), and OS (HR, 0.642; p = 0.124). Conclusion: Although there was a difference in recurrence rate between the two groups, multivariable analysis indicated that the diversion technique after RARC did not affect the oncologic outcomes. Large prospective studies with long-term follow-up are warranted to verify the oncologic outcomes of ICUD and ECUD following RARC. | Ham, Won Sik; Rha, Koon Ho; Han, Woong Kyu; Kwon, Tae Gyun; Kim, Tae Hwan; Jeon, Seung Hyun; Lee, Sang Hyup; Kang, Seok Ho; Kang, Sung Gu; Nam, Jong Kil; Kim, Wansuk; Jeong, Byung Chang; Ku, Ja Hyun; Oh, Jong Jin; Lee, Sang Chul; Lee, Ji Yeol; Hong, Sung Hoo; Lee, Young Goo; Lee, Yong Seong; Park, Sung Yul; Yoon, Young Eun; Kim, Jongchan | Yonsei Univ, Coll Med, Dept Urol, 50-1 Yonsei Ro, Seoul 03722, South Korea; Yonsei Univ, Coll Med, Urol Sci Inst, 50-1 Yonsei Ro, Seoul 03722, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Kyung Hee Univ, Sch Med, Dept Urol, Seoul, South Korea; Korea Univ, Coll Med, Dept Urol, Seoul, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Urol, Yangsan, South Korea; Inje Univ, Coll Med, Busan Paik Hosp, Dept Urol, Busan, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Urol, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Urol, Seoul, South Korea; Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Dept Urol, Seoul, South Korea; Hallym Univ, Sch Med, Kangnam Sacred Heart Hosp, Dept Urol, Seoul, South Korea; Hallym Univ, Coll Med, Sacred Heart Hosp, Dept Urol, Anyang, South Korea; Hanyang Univ, Coll Med, Dept Urol, Seoul, South Korea; Yonsei Univ Hlth Syst, Yongin Severance Hosp, Dept Urol, Yongin, South Korea | Jeon, Seung Hyun/AFN-3212-2022; Lee, Hye/J-2154-2015; Yoon, Youngeun/HOC-1137-2023; LEE, Sunghee/HCH-4510-2022; Lee, Jung-Seok/L-6826-2019 | 23097952400; 7003388459; 7401899857; 15073765400; 57797823600; 7203005251; 57192520266; 7405684686; 35995660400; 8653467500; 57049819200; 7102237943; 36800523000; 24468588100; 57202327303; 57298704300; 37030299600; 15033760000; 36068330000; 12242293700; 55965389800; 57210894884 | lumpakcef@yuhs.ac; | JOURNAL OF ENDOUROLOGY | J ENDOUROL | 0892-7790 | 1557-900X | 35 | 10 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 2.619 | 62.8 | 0.7 | 2025-07-30 | 8 | 8 | urinary bladder neoplasm; robotic surgical procedure; cystectomy; urinary diversion | INVASIVE BLADDER-CANCER; PERIOPERATIVE OUTCOMES; COMPLICATIONS; LAPAROSCOPY; RECURRENCE | cystectomy; robotic surgical procedure; Urinary bladder neoplasm; urinary diversion | Cystectomy; Humans; Neoplasm Recurrence, Local; Postoperative Complications; Prospective Studies; Republic of Korea; Retrospective Studies; Robotic Surgical Procedures; Robotics; Treatment Outcome; Urinary Bladder Neoplasms; Urinary Diversion; adult; aged; bladder cancer; cancer recurrence; cancer specific survival; comparative effectiveness; Conference Paper; cystectomy; extracorporeal urinary diversion; female; follow up; human; intracorporeal urinary diversion; Korean (people); major clinical study; male; overall survival; recurrence free survival; retrospective study; risk factor; robot assisted surgery; surgical technique; survival rate; tertiary care center; treatment outcome; bladder tumor; cystectomy; postoperative complication; prospective study; robotics; South Korea; tumor recurrence; urinary diversion | English | 2021 | 2021-10 | 10.1089/end.2021.0067 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Prominent hypointense vessel on susceptibility-weighted images accompanying hyperacute and acute large infarction | Background Multiple prominent hypointense vessels on susceptibility-weighted image (SWI) have been found in the ischemic territory of patients with acute ischemic stroke. SWI is suitable for venous imaging. Purpose To evaluate the conditions of prominent hypointense vessel (PHV) in hyperacute and acute cerebral infarctions using susceptibility-weighted image (SWI). Materials and methods Magnetic resonance images, including SWI, of 284 patients with acute infarction were evaluated. Based on lesion size, the infarction was classified as a small ( 3 cm) infarction. Stage of infarction was classified as hyperacute ( 6 h, < 1 week) on the basis of the onset of stroke. The site of infarction was categorised as a deep grey matter or a mixed (cortical and/or deep grey matter) infarction. The venous structures were analysed qualitatively for the calibre difference between ipsilateral and contralateral hemispheres. We quantitatively analysed the relationship between the size of areas with PHV on SWI and the abnormalities on MR angiography, apparent diffusion coefficient value, and signal intensity on T2WI in the 271 patients. Results PHV over the infarction site was observed in 54.1% (137/253) of the large infarctions, and 19.3% (6/31) of the small infarctions on SWI. PHV was demonstrated in 63.1% (118/187) of mixed infarctions and 25.8% (25/97) of deep grey matter infarctions, and 59.2% (58/98) in hyperacute and 45.7% (85/186) of acute infarctions. The presence of PHV was statistically significant in the size and region of cerebral infarction (p < 0.05), and was not significant in the stage of infarction (p = 0.137). Quantitative analysis revealed significant differences in the MRA abnormalities and ADC values in the PHV ( +) group (p < 0.05) and no significant difference in the T2WI SI ratio in the PHV ( +) group (p = 0.086), compared with PHV (-) group. Conclusion PHV on SWI was more prominent at the portions with the large and mixed infarctions. PHV was observed both in hyperacute and acute infarction. | Kim, Yong-Woo; Choi, Yoon Young; Park, Shin Young; Kim, Hak Jin; Kim, Yong Sun | Pusan Natl Univ, Yangsan Hosp, Res Inst Convergence Biomed Sci & Technol, Dept Radiol,Sch Med, Yangsan, South Korea; Pusan Natl Univ, Pusan Natl Univ Hosp, Sch Med, Dept Radiol,Med Res Inst, Pusan, South Korea; Kyungpook Natl Univ, Coll Med, Dept Radiol, Daeku, South Korea | Choi, Hayoung/AAI-8638-2020 | 55644003473; 57203086834; 57222477763; 55766549800; 57095278300 | hakjink@pusan.ac.kr; | JAPANESE JOURNAL OF RADIOLOGY | JPN J RADIOL | 1867-1071 | 1867-108X | 39 | 7 | SCIE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2021 | 2.701 | 62.9 | 0.68 | 2025-07-30 | 6 | 7 | Brain infarction; MR; Haemodynamics; SWI; Dilated vein; Prominent hypointense vessel | Brain infarction; Dilated vein; Haemodynamics; MR; Prominent hypointense vessel; SWI | Acute Disease; Aged; Brain; Brain Infarction; Cerebral Arteries; Diffusion Magnetic Resonance Imaging; Female; Humans; Male; adult; apparent diffusion coefficient; Article; blood vessel; body weight; brain infarction; cerebrovascular accident; controlled study; diffusion weighted imaging; female; gray matter; hemodynamics; human; magnetic resonance angiography; major clinical study; male; middle aged; nuclear magnetic resonance imaging; quantitative analysis; retrospective study; susceptibility weighted imaging; acute disease; aged; brain; brain artery; brain infarction; diagnostic imaging; procedures | English | 2021 | 2021-07 | 10.1007/s11604-021-01107-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Letter | A retrospective case series of 10 patients with malignant melanomas arising from small- and medium-sized congenital melanocytic nevi in South Koreans | Kim, Jun Young; Kim, Seok Min; Park, Kyung Duck; Jang, Yong Hyun; Lee, Weon Ju; Lee, Seok-Jong | Kyungpook Natl Univ, Sch Med, Dept Dermatol, Kyungpook Natl Univ Hosp, Daegu, South Korea | Lee, Joong/A-5417-2013 | 35310922800; 57200860205; 55767995700; 57016046400; 24474659000; 56013454400 | seokjong@knu.ac.kr; | INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY | INDIAN J DERMATOL VE | 0378-6323 | 0973-3922 | 87 | 2 | SCIE | DERMATOLOGY | 2021 | 2.217 | 63.0 | 0.8 | 2025-07-30 | 4 | 4 | RISK | Adult; Aged, 80 and over; Female; Humans; Male; Melanoma; Middle Aged; Nevus, Pigmented; Republic of Korea; Retrospective Studies; Skin Neoplasms; Young Adult; adult; Breslow thickness; cancer staging; case report; clinical article; cutaneous melanoma; distant metastasis; epiluminescence microscopy; female; histology; histopathology; human; human tissue; Letter; male; melanoma; metastasis; middle aged; nevus cell; pigmented nevus; precursor; retrospective study; sentinel lymph node biopsy; skin ulcer; young adult; complication; melanoma; pigmented nevus; skin tumor; South Korea; very elderly | English | 2021 | 2021 (MAR-APR) | 10.25259/ijdvl_718_19 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Collismycin C reduces HMGB1-mediated septic responses and improves survival rate in septic mice | We examined the effects of a 2,2 '-bipyridine containing natural product, collismycin C on high mobility group box 1 (HMGB1, septic mediator)-mediated septic responses and survival rate in a mouse sepsis model. Collismycin C inhibited the HMGB1 release and downregulated HMGB1-mediated inflammatory responses in human endothelial cells. Collismycin C also inhibited HMGB1-induced hyperpermeability and leukocyte migration in mice. In addition, collismycin C treatment reduced CLP-induced HMGB1 release and sepsis-related mortality and pulmonary damage in vivo. Our results indicate that collismycin C is a potential therapeutic agent for the treatment of severe vascular inflammatory diseases by inhibiting HMGB1 signaling pathway. | Kim, Eonmi; Ku, Sae-Kwang; Yang, Sumin; Lee, Bong-Seon; Kim, Geum Jin; Choi, Hyukjae; Bae, Jong-Sup | Yeungnam Univ, Coll Pharm, 280 Daehak Ro, Gyongsan 38541, Gyeongbuk, South Korea; Daegu Haany Univ, Coll Korean Med, Dept Anat & Histol, Gyongsan 38610, South Korea; Kyungpook Natl Univ, Coll Pharm, BK21 Plus KNU Multiom Based Creat Drug Res Team, CMRI,Res Inst Pharmaceut Sci, Daegu 41566, South Korea | Kim, Seong-Hun/ABF-2927-2020; Bae, Jong-Sup/AAU-9724-2020 | 57199802851; 7006331005; 57204186412; 57204178543; 54585532800; 7404339587; 16021543200 | h5choi@yu.ac.kr;baejs@knu.ac.kr; | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | J ASIAN NAT PROD RES | 1028-6020 | 1477-2213 | 23 | 1 | SCIE | CHEMISTRY, APPLIED;CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY;PLANT SCIENCES | 2021 | 1.61 | 63.0 | 0 | 2025-07-30 | 1 | 2 | Collismycin C; endothelium; HMGB1; sepsis | GROUP BOX 1; SEVERE SEPSIS; CAERULOMYCIN; EPIDEMIOLOGY; MANAGEMENT | Collismycin C; endothelium; HMGB1; sepsis | 2,2'-Dipyridyl; Animals; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Molecular Structure; Sepsis; Survival Rate; antiinfective agent; collismycin c; high mobility group B1 protein; immunoglobulin enhancer binding protein; interleukin 6; sirtuin 1; tumor necrosis factor; unclassified drug; 2,2' bipyridine; collismycin C; high mobility group B1 protein; lipopolysaccharide; animal cell; animal experiment; animal model; animal tissue; Article; cell adhesion; cell migration; competitive ELISA; controlled study; drug effect; endothelium cell; human; human cell; in vivo study; leukocyte migration; lung injury; male; mortality; mouse; nonhuman; protein acetylation; protein secretion; sepsis; signal transduction; survival rate; vasculitis; animal; C57BL mouse; chemical structure; metabolism; survival rate; umbilical vein endothelial cell | English | 2021 | 2021-01-02 | 10.1080/10286020.2019.1706497 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Letter | Cutaneous lymphoid hyperplasia developing on the site of a positive intradermal allergy test to cefotetan | Lee, Eun Hye; Kim, Jun Young | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Dermatol, Daegu, South Korea | 57189661699; 35310922800 | 198kjy@hanmail.net; | INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY | INDIAN J DERMATOL VE | 0378-6323 | 0973-3922 | 87 | 5 | SCIE | DERMATOLOGY | 2021 | 2.217 | 63.0 | 0 | 2025-07-30 | 0 | 0 | Adult; Anti-Bacterial Agents; Cefotetan; Female; Humans; Hyperplasia; Intradermal Tests; Pseudolymphoma; cefotetan; cephalosporin; triamcinolone; antiinfective agent; cefotetan; adult; allergy; allergy test; case report; clinical article; delayed hypersensitivity; dermatofibrosarcoma protuberans; drug hypersensitivity; eosinophil; female; histopathology; human; human tissue; Letter; lymph follicle; lymphocytic infiltration; lymphoid hyperplasia; punch biopsy; urticaria; adverse event; hyperplasia; intracutaneous test; pathology; pseudolymphoma | English | 2021 | 2021 (SEP-OCT) | 10.25259/ijdvl_922_19 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Inhibitory effects of aloin on TGFBIp-mediated septic responses | Aloin is the major anthraquinone glycoside obtained from the Aloe species. Transforming growth factor beta-induced protein (TGFBIp) is an extracellular matrix protein and released by primary human umbilical vein endothelial cells (HUVECs) and functions as a mediator of experimental sepsis. We hypothesized that aloin could reduce TGFBIp-mediated severe inflammatory responses in HUVECs and mice. Aloin effectively inhibited lipopolysaccharide (LPS)-induced release of TGFBIp and suppressed TGFBIp-mediated septic responses. Aloin suppressed TGFBIp-induced sepsis lethality and pulmonary injury. Therefore, aloin is a potential therapeutic agent for various severe vascular inflammatory diseases, with inhibition of the TGFBIp signaling pathway as the mechanism of action. | Lee, In-Chul; Bae, Jong-Sup | Seowon Univ, Dept Cosmet Sci & Technol, Cheongju 28674, South Korea; Kyungpook Natl Univ, Coll Pharm, CMRI, Res Inst Pharmaceut Sci,BK21 Plus KNU Multiom Bas, Daegu 41566, South Korea | Bae, Jong-Sup/AAU-9724-2020 | 56390536600; 16021543200 | baejs@knu.ac.kr; | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | J ASIAN NAT PROD RES | 1028-6020 | 1477-2213 | 23 | 2 | SCIE | CHEMISTRY, APPLIED;CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY;PLANT SCIENCES | 2021 | 1.61 | 63.0 | 0.37 | 2025-07-30 | 5 | 4 | Aloin; TGFBIp; sepsis; severe inflammation; HUVEC | CELL-LINE; GROWTH; PROTEIN; BETA-IG-H3; EMODIN; ADHESION | Aloin; HUVEC; sepsis; severe inflammation; TGFBIp | Animals; Emodin; Extracellular Matrix Proteins; Human Umbilical Vein Endothelial Cells; Mice; Mice, Inbred C57BL; Molecular Structure; Transforming Growth Factor beta; alanine aminotransferase; aloin; alphaVbeta5 integrin; antiinflammatory agent; aspartate aminotransferase; creatinine; endothelial leukocyte adhesion molecule 1; immunoglobulin enhancer binding protein; intercellular adhesion molecule 1; matrix protein; messenger RNA; mitogen activated protein kinase; mitogen activated protein kinase 1; mitogen activated protein kinase p38; transforming growth factor beta induced protein; unclassified drug; vascular cell adhesion molecule 1; vitronectin receptor; alloin; emodin; scleroprotein; transforming growth factor beta; alanine aminotransferase blood level; animal experiment; animal model; antiinflammatory activity; Article; aspartate aminotransferase blood level; blood vessel permeability; cardiovascular inflammation; cell adhesion; cell migration; competitive ELISA; controlled study; creatinine blood level; disease severity; drug effect; drug mechanism; experimental sepsis; histopathology; human; human cell; HUVEC cell line; in vivo study; lethality; leukocyte migration; lung injury; male; mortality; mouse; neutrophil; nonhuman; pathogenesis; protein expression; protein function; protein secretion; real time polymerase chain reaction; signal transduction; urea nitrogen blood level; Western blotting; animal; C57BL mouse; chemical structure; umbilical vein endothelial cell | English | 2021 | 2021-02-01 | 10.1080/10286020.2019.1711066 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Letter | replyLetter in response to the article: "A retrospective case series of ten patients with malignant melanomas arising from small- and medium-sized congenital melanocytic nevi in South Koreans" | Kim, Jun Young | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Dermatol, Daegu, South Korea | 35310922800 | 198kjy@hanmail.net; | INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY | INDIAN J DERMATOL VE | 0378-6323 | 0973-3922 | 87 | 6 | SCIE | DERMATOLOGY | 2021 | 2.217 | 63.0 | 0 | 2025-07-30 | 0 | 0 | Humans; Melanoma; Nevus, Pigmented; Republic of Korea; Research; Retrospective Studies; human; melanoma; pigmented nevus; research; retrospective study; South Korea | English | 2021 | 2021 (NOV-DEC) | 10.25259/ijdvl_579_2021 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Suppressive effects of aloin on polyphosphate-mediated vascular inflammatory responses | Human endothelial cells-derived polyphosphate (PolyP) is one of the pro-inflammatory mediators as suggested by the previous reports. Aloin is the major anthraquinone glycoside obtained from the Aloe species and exhibits anti-inflammatory and anti-oxidative activities. Aloin inhibits PolyP-mediated barrier disruption, the expressions of cell adhesion molecules, and adhesion/migration of leukocyte to HUVEC. PolyP-induced NF-kappa B activation and the productions of TNF-alpha and IL-6 were inhibited by aloin in HUVECs. These anti-inflammatory functions of aloin were confirmed in PolyP-injected mice. In conclusion, based on the anti-inflammatory effects of aloin in PolyP-mediated septic response, aloin has therapeutic potential for various systemic inflammatory diseases. | Lee, In-Chul; Bae, Jong-Sup | Seowon Univ, Dept Cosmet Sci & Technol, Cheongju, South Korea; Kyungpook Natl Univ, Coll Pharm, CMRI, Res Inst Pharmaceut Sci,BK21 Plus KNU Multiom Bas, Daegu 41566, South Korea | Bae, Jong-Sup/AAU-9724-2020 | 56390536600; 16021543200 | baejs@knu.ac.k; | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | J ASIAN NAT PROD RES | 1028-6020 | 1477-2213 | 23 | 1 | SCIE | CHEMISTRY, APPLIED;CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY;PLANT SCIENCES | 2021 | 1.61 | 63.0 | 0.65 | 2025-07-30 | 9 | 7 | Aloin; barrier integrity; polyphosphate; vascular permeability | ADHESION; EMODIN | Aloin; barrier integrity; polyphosphate; vascular permeability | Animals; Emodin; Human Umbilical Vein Endothelial Cells; Mice; Mice, Inbred C57BL; Molecular Structure; NF-kappa B; Polyphosphates; Tumor Necrosis Factor-alpha; alanine aminotransferase; aloin; aspartate aminotransferase; creatinine; dabrafenib; endothelial leukocyte adhesion molecule 1; immunoglobulin enhancer binding protein; intercellular adhesion molecule 1; interleukin 6; lactate dehydrogenase; messenger RNA; mitogen activated protein kinase 1; mitogen activated protein kinase 3; mitogen activated protein kinase p38; nitrogen; polyphosphate; tumor necrosis factor; urea; vascular cell adhesion molecule 1; alloin; emodin; immunoglobulin enhancer binding protein; tumor necrosis factor; alanine aminotransferase blood level; animal experiment; animal model; animal tissue; antiinflammatory activity; Article; aspartate aminotransferase blood level; blood vessel permeability; cell adhesion; cell viability; controlled study; cytokine production; data analysis software; down regulation; drug cytotoxicity; enzyme linked immunosorbent assay; enzyme phosphorylation; human; human cell; in vitro study; lactate dehydrogenase blood level; lethality; leukocyte migration; male; mouse; mRNA expression level; neutrophil; nonhuman; overall survival; protection; protein expression level; signal transduction; single drug dose; survival rate; umbilical vein endothelial cell; upregulation; urea nitrogen blood level; vasculitis; animal; C57BL mouse; chemical structure; metabolism | English | 2021 | 2021-01-02 | 10.1080/10286020.2020.1724969 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Letter | Unexpected high fluorine-18 fluorodeoxyglucose uptake on positron emission tomography/computed tomography of a benign cellular blue nevus | Lee, Hyun Ji; Kim, Jun Young | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Dermatol, Daegu, South Korea | 57207758693; 35310922800 | 198kjy@hanmail.net; | INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY | INDIAN J DERMATOL VE | 0378-6323 | 0973-3922 | 87 | 2 | SCIE | DERMATOLOGY | 2021 | 2.217 | 63.0 | 0 | 2025-07-30 | 0 | 0 | Adult; Female; Fluorodeoxyglucose F18; Humans; Nevus, Blue; Positron Emission Tomography Computed Tomography; Skin Neoplasms; fluorodeoxyglucose f 18; fluorodeoxyglucose f 18; adult; blue nevus; breast cancer; case report; chromosome aberration; clinical article; female; fluorescence in situ hybridization; gene mutation; histopathology; human; human tissue; hypermetabolism; immunohistochemistry; incisional biopsy; Letter; positron emission tomography; positron emission tomography-computed tomography; blue nevus; diagnostic imaging; metabolism; positron emission tomography-computed tomography; procedures; skin tumor | English | 2021 | 2021 (MAR-APR) | 10.25259/ijdvl_55_20 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | Meeting Abstract | Adherence and associated factors of treatment regimen in drug-susceptible tuberculosis patients | Bea, Sungho; Lee, Hyesung; Kim, Ju Hwan; Jang, Seung Hun; Son, Hyunjin; Kwon, Jin-Won; Shin, Ju-Young | Sungkyunkwan Univ, Sch Pharm, Suwon, Gyeonggi Do, South Korea; Hallym Univ, Hallym Univ Sacred Heart Hosp, Coll Med, Div Pulm Allergy & Crit Care Med, Chunchon, South Korea; Dong A Univ, Coll Med, Dept Prevent Med, Busan, South Korea; Kyungpook Natl Univ, Coll Pharm, Daegu, South Korea; Kyungpook Natl Univ, Pharmaceut Sci Res Inst, Daegu, South Korea; Sungkyunkwan Univ SKKU, Sch Pharm, Suwon, South Korea | Kim, Ju Hwan/ADG-3199-2022; Lee, Hyesung/GPC-5111-2022 | PHARMACOEPIDEMIOLOGY AND DRUG SAFETY | PHARMACOEPIDEM DR S | 1053-8569 | 1099-1557 | 30 | SCIE | PHARMACOLOGY & PHARMACY;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2021 | 2.732 | 63.1 | 0 | English | 2021 | 2021-08 | 바로가기 | 바로가기 |
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