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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Alteration in skeletal posture between breast reconstruction with latissimus dorsi flap and mastectomy: a prospective comparison study Background: The latissimus dorsi (LD) flap is used in cases of immediate breast reconstruction after total or partial mastectomy. However, studies on the effect of unilateral LD flap reconstruction on skeletal posture and comparison with results from mastectomy-only have been sparse. Thus in this prospective, observational study, we compared skeletal posture and functional recovery in patients who underwent a mastectomy-only versus those who underwent breast reconstruction with a LD flap after mastectomy. Methods: From January 2018 to February 2020, a total of 54 patients were enrolled. The control group included 23 patients who underwent mastectomy-only and the experimental group included 31 patients who underwent breast reconstruction using a LD flap immediately after mastectomy. We assessed the Cobb's angle in spine X-rays, parameters derived from photometry, computed tomography (CT), and 3D scanning preoperatively (T0), 6 months post-surgery (T1), and 1-year post-surgery (T2). We also evaluated functional outcomes, such as pain intensity, disability of the upper extremities, and quality of life. Results: In the control and experimental groups, the average age was 58.7/46.2 years, body mass index (BMI) was 24.9/22.5, and excised mass weight was 386.8/259.1 g, respectively. In the control group, differences in the Cobb's angle were significant between T0 and T2 (P=0.003). There were significant differences in the Cobb's angle and time interaction effects between the two groups (P=0.015). The degree of change in the Cobb's angle between T0 and T1 was positively correlated with change in the vertical distance from the 3D scanner midline to the nipple (P=0.009). Conclusions: The experimental group showed improved recovery in skeletal posture compared to the control group. Further, discovering the parameters that can predict the change of skeletal posture through a 3D scanner will have clinical significance. Accordingly, performing breast reconstruction by unilaterally applying the LD muscle is a safe, reliable, and useful method of autologous tissue transfer for breast cancer patients. Lee, Joon Seok; Park, Eunhee; Lee, Jung Ho; Lee, Jeeyeon; Park, Ho Yong; Yang, Jung Dug; Jung, Tae-Du Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, 130 Dongduk Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Rehabil Med, 130 Dongduk Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea Yang, Jung/R-7806-2019; PARK, JUN-YOUNG/P-5981-2015; LEE, JIN/Q-3108-2018; Lee, Jong-Mok/KVY-9550-2024; Lee, Jungho/AAJ-7137-2020 56496041000; 56107216400; 57202925792; 37079213100; 56564377200; 55171704700; 36622364500 lambyang@knu.ac.kr;teeed0522@knu.ac.kr; GLAND SURGERY GLAND SURG 2227-684X 2227-8575 10 5 SCIE SURGERY 2021 2.16 60.3 1.82 2025-07-30 12 13 Mastectomy; mammaplasty; quality of life; surgical flaps KOREAN VERSION mammaplasty; Mastectomy; quality of life; surgical flaps English 2021 2021-05 10.21037/gs-21-31 바로가기 바로가기 바로가기 바로가기
Article Comparison of healthcare resource utilization and medical costs between patients with seropositive and seronegative rheumatoid arthritis Objectives: To compare healthcare utilization and medical costs between patients with seronegative (SN) and seropositive (SP) rheumatoid arthritis (RA). Methods: We conducted a nationwide population study using the Korean health insurance claims database in 2016. We divided patients with RA into SN and SP groups and compared healthcare utilization including medications, medical utilization, and direct medical costs for 1 year between the groups in a cross-sectional analysis. Differences in costs between patients with SPRA and SNRA were assessed using the quantile regression model. We performed longitudinal analysis using data from 2012 and 2016 to examine changes over time. Results: A total of 103,815 SPRA and 75,809 SNRA patients were included in the analyses. The SPRA group used significantly more methotrexate (73.2% versus 30.3%) and biologic agents (7.9% versus 2.9%) than the SNRA group. The number of RA-related outpatient visits [6.0 +/- 3.7 versus 4.4 +/- 4.0 times/year, standardized difference (SD) = 0.41] and annual medical costs per patient ($1027 versus $450/year, SD = 0.25) were higher in the SPRA group than the SNRA group. Quantile regression results indicated that the incremental cost of seropositivity on total medical costs of RA patients gradually increased as medical costs approached the upper quantile. The annual direct medical costs for each patient between 2012 and 2016 increased in both groups: by 25.1% in the SPRA group and 37.6% in the SNRA group. Conclusion: Annual RA-related direct medical costs and RA-related healthcare utilization per patient are higher in patients with SPRA than those with SNRA. Kim, Hyoungyoung; Cho, Soo-Kyung; Choi, Seongmi; Im, Seul Gi; Jung, Sun-Young; Jang, Eun Jin; Sung, Yoon-Kyoung Andong Natl Univ, Dept Informat Stat, Andong 36729, Gyeongsangbuk D, South Korea; Hanyang Univ, Dept Rheumatol, Hosp Rheumat Dis, Wangshimni Ro 222-1, Seoul 04763, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Hlth Insurance Res Inst, Natl Hlth Insurance Serv, Wonju, South Korea; Chung Ang Univ, Coll Pharm, Seoul, South Korea 57202108695; 35185890800; 57211676692; 57201022006; 57207445502; 37861741600; 15754508900 jejstat@gmail.com;sungyk@hanyang.ac.kr; THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE THER ADV MUSCULOSKEL 1759-720X 1759-7218 13 SCIE RHEUMATOLOGY 2021 3.625 60.3 0.59 2025-07-30 4 5 medical utilization; medication; rheumatoid arthritis; seropositivity ANTICITRULLINATED PROTEIN ANTIBODY; DISEASE-ACTIVITY; RADIOGRAPHIC PROGRESSION; COHORT; POSITIVITY medical utilization; medication; rheumatoid arthritis; seropositivity abatacept; corticosteroid; cyclic citrullinated peptide antibody; etanercept; golimumab; infliximab; interleukin 17; interleukin 6; rituximab; tofacitinib; adult; algorithm; Article; controlled study; cross-sectional study; diagnostic test accuracy study; disease activity; drug cost; female; fibromyalgia; health care; health care cost; health care organization; health care utilization; health insurance; hospitalization; human; interstitial lung disease; interstitial pneumonia; length of stay; major clinical study; male; multicenter study; osteoporosis; outpatient; pelvic organ prolapse; population research; predictive value; prescription; remission; rheumatoid arthritis; synovitis; systemic lupus erythematosus; total knee arthroplasty English 2021 2021-06 10.1177/1759720x211024830 바로가기 바로가기 바로가기 바로가기
Article Delayed unilateral hematoma after reconstructive and aesthetic breast surgery with implants in Asian patients: two case reports Hematomas represent one of the postoperative complications in patients undergoing reconstructive or aesthetic breast surgery with a silicone implant. Although there are few reports of intracapsular hematoma, those presenting late hematoma after reconstructive and aesthetic augmentation surgeries are rarer. This study reported two Asian patients with late hematoma after reconstruction and aesthetic breast surgery. A 54-year-old female patient underwent bilateral nipple-sparing mastectomy with immediate breast reconstruction using anatomically shaped textured implant for intraductal carcinoma in August 2019. Contralateral nipple-sparing mastectomy was performed for the BRCA gene mutation on the left breast, which was immediately reconstructed with an anatomically shaped textured implant. In a 1-year postoperative magnetic resonance imaging evaluation, an extracapsular hematoma was found on the right side, which was removed following the removal of both implants. Another case was a 63-year-old female patient who underwent augmentation of both breasts with smooth round implants and experienced right unilateral swelling and painless firmness about 30 years postoperatively. A preoperative magnetic resonance imaging evaluation showed both intracapsular and extracapsular ruptures on the right breast and a bulging implant herniation on the left breast. During the operation, hematoma, implants, and capsule were all removed. The excised capsule was sent for histological evaluation. Slightly dark colored blood was emptied before removing the semisolid-state intracapsular hematoma. In both cases, the patients responded well postoperatively and were discharged to their homes with no postsurgical complications, including seroma, or additional hematoma on the breasts. The etiology of late hematoma following breast augmentation or reconstruction has been poorly characterized. Further reports are needed to clearly establish the reasons for this increase in late hematoma formation. Lee, Jong Ho; Hong, Hyun Ki; Kim, Won Hwa; Kim, Hye Jung; Lee, Jeeyeon; Park, Ho Yong; Yang, Jung Dug; Lee, Joon Seok Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Radiol, Daegu, South Korea LEE, JIN/Q-3108-2018; Lee, Jong-Mok/KVY-9550-2024; Yang, Jung/R-7806-2019 57212661146; 57210147816; 36081886500; 57203506201; 37079213100; 56564377200; 55171704700; 56496041000 leejspo@knu.ac.kr; GLAND SURGERY GLAND SURG 2227-684X 2227-8575 10 4 SCIE SURGERY 2021 2.16 60.3 0.17 2025-07-30 1 1 Hematoma; breast implantation; implant capsular contracture; hematoma post breast reconstruction; intracapsular hematoma; extracapsular hematoma CAPSULAR HEMATOMA; COMPLICATION breast implantation; extracapsular hematoma; Hematoma; hematoma post breast reconstruction; implant capsular contracture; intracapsular hematoma English 2021 2021-04 10.21037/gs-20-854 바로가기 바로가기 바로가기 바로가기
Article Porcine training models for endoscopic and robotic reconstructive breast surgery: a preliminary study Background: With recent advances in surgical techniques, minimally invasive methods for reconstructive breast surgery are being investigated. To enhance surgical proficiency through training and minimize predictable complications before human application, we conducted a preliminary experimental study of reconstructive breast surgery using a porcine model. Methods: Between February and March 2019, four 3-month-old pigs underwent a bilateral mastectomy and immediate breast reconstruction with a latissimus dorsi (LD) flap or silicone implants. After performing the mastectomy by dissecting the pectoralis profundus in the subcutaneous plane, the pig was placed in the decubitus position, and ultrasound-guided marking was used to design the LD flap. The thoracodorsal artery was marked, and a 4-cm incision was made on the midaxillary line. An additional endoscopic incision was made in the inferior margin of the LD flap; a 2-hole approach was used for endoscopic LD flap elevation. In the silicone implant model, a silicone implant (Allergan, smooth, round type, 90 cc) was placed using a single incision (4-5 cm). Results: Eight mastectomies followed by breast reconstruction with LD flap elevation or silicone implant models were performed on four pigs. Serious complications, such as active bleeding, did not occur. However, heat dispersion to the skin flap that became thinner by endoscopic dissection caused a second-degree burn in one pig. Conclusions: This preliminary study of endoscopic or robot-assisted minimally invasive reconstructive breast surgery demonstrates that a porcine training model is a highly valuable experimental model for surface anatomy verification, incision plan selection, instrument selection, operator proficiency enhancement, and complication prevention. Lee, Joon Seok; Lee, Jeeyeon; Kim, Yun Hyun; Park, Ho Yong; Yang, Jung Dug Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, 130 Dongduk Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, 807 Hoguk Ro, Daegu 41944, South Korea LEE, JIN/Q-3108-2018; Yang, Jung/R-7806-2019; PARK, JUN-YOUNG/P-5981-2015; Lee, Jong-Mok/KVY-9550-2024 56496041000; 37079213100; 57212668506; 56564377200; 55171704700 phy123@knu.ac.kr;lambyang@knu.ac.kr; GLAND SURGERY GLAND SURG 2227-684X 2227-8575 10 8 SCIE SURGERY 2021 2.16 60.3 0.33 2025-07-30 3 2 Reconstructive breast surgery; porcine training model; endoscopic and robotic surgery MUSCLE; PIG endoscopic and robotic surgery; porcine training model; Reconstructive breast surgery English 2021 2021-08 10.21037/gs-21-398 바로가기 바로가기 바로가기 바로가기
Article Simultaneous nipple reconstruction in autologous breast reconstruction Background: Reconstruction of the nipple-areola complex is the final step in surgical restoration of the breast. Nipple-areola reconstruction was previously done after an interval of several months using variable techniques, often resulting in low projection and flattened breast mound over time. We present algorithm of simultaneous nipple reconstruction (SNR) that leaves adequate residual projection and naturally shaped breast mound. Methods: Forty patients underwent a skin-sparing mastectomy and nipple excision between October 2016 and December 2020. In the control group, 21 patients underwent delayed nipple reconstruction for 6 months after breast reconstruction. The experimental group of 19 patients underwent nipple and breast reconstruction simultaneously. We collected relevant information and photographs of nipple profiles of both groups in the preoperative, postoperative 6-month, and postoperative 1-year time periods. We also examined the ratio between the reconstructed and contralateral nipples. Results: Scores regarding patient satisfaction questionnaire averaged higher in experimental groups to every category. The control group's scores gradually declined over time and the experimental group showed lesser decline. At the 1-year postoperative follow-up, the mean projection of the immediately reconstructed nipple was approximately the same as the contralateral nipple at 91%, whereas the delayed reconstructed nipple resulted in a 77% ratio. Conclusions: Nipple reconstruction should no longer be considered as a secondary complement to immediate breast reconstruction. The nipple appears to be essential component of breast reconstruction for patient. SNR with immediate breast reconstruction is a simple and reliable technique, giving stable aesthetic results over time. Lee, Jong Ho; Ryu, Jeong Yeop; Lee, Jung Ho; Lee, Jeeyeon; Park, Ho Yong; Yang, Jung Dug; Lee, Joon Seok Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea Lee, Jong-Mok/KVY-9550-2024; Yang, Jung/R-7806-2019; PARK, JUN-YOUNG/P-5981-2015; LEE, JIN/Q-3108-2018; Lee, Keon Jae/C-1722-2011; Lee, Jungho/AAJ-7137-2020; Ryu, Jeong Yeop/GLQ-9419-2022 57212661146; 56366349400; 57202925792; 37079213100; 56564377200; 55171704700; 56496041000 leejspo@knu.ac.kr; GLAND SURGERY GLAND SURG 2227-684X 2227-8575 10 10 SCIE SURGERY 2021 2.16 60.3 0.5 2025-07-30 5 6 Simultaneous nipple reconstruction (SNR); one-stage nipple; breast reconstruction AREOLA COMPLEX RECONSTRUCTION; SPARING MASTECTOMY; FLAP; IMMEDIATE; PROJECTION; CARTILAGE breast reconstruction; one-stage nipple; Simultaneous nipple reconstruction (SNR) English 2021 2021-10 10.21037/gs-21-338 바로가기 바로가기 바로가기 바로가기
Article The Vulnerability Problem of Business Ecosystems under Global Decoupling Cha, Hongryol; Wu, Jie; Kotabe, Masaaki Kyungpook Natl Univ, Sch Business Adm, Seoul, South Korea; Univ Aberdeen, Aberdeen, Scotland; Waseda Univ, Tokyo, Japan; Univ Hawaii Manoa, Honolulu, HI 96822 USA Wu, Jie/LCE-7752-2024; KOTABE, MASAAKI/ABC-6239-2020; wu, jie/LCE-7752-2024; Cha, Hongryol/JHV-1562-2023 57160699500; 55551418400; 6701780100 jie.wu@abdn.ac.uk; MANAGEMENT AND ORGANIZATION REVIEW MANAGE ORGAN REV 1740-8776 1740-8784 17 3 SSCI MANAGEMENT 2021 3.776 60.3 0.4 2025-07-30 8 10 English 2021 2021-07 10.1017/mor.2021.30 바로가기 바로가기 바로가기 바로가기
Article A Performance Evaluation of Potential Intensity over the Tropical Cyclone Passage to South Korea Simulated by CMIP5 and CMIP6 Models Potential intensity (PI) is a metric for climate model evaluation of TC-related thermodynamic conditions. However, PI is utilized usually for assessing basin-wide TC-related thermodynamic conditions, and not for evaluating TC passage to a certain region. Here we evaluate model-simulated PI over the passage of TCs affecting South Korea (KOR PI) as well as the PI over the entire western North Pacific basin (WNP PI) using 25 CMIP5 and 27 CMIP6 models. In terms of pattern correlations and bias-removed root mean square errors, CMIP6 model performances for KOR PI are found to be noticeably improved over CMIP5 models in contrast to negligible improvement for WNP PI, although it is not in terms of normalized standard deviations. This implies that thermodynamic condition on the route of TCs affecting South Korea is likely better captured by CMIP6 models than CMIP5 models. Park, Doo-Sun R.; Kim, Hyeong-Seog; Kwon, Minho; Byun, Young-Hwa; Kim, Maeng-Ki; Chung, Il-Ung; Park, Jeong-Soo; Min, Seung-Ki Kyungpook Natl Univ, Dept Earth Sci Educ, Daegu 41566, South Korea; Korea Maritime & Ocean Univ, Ocean Sci & Technol Sch, Busan 49112, South Korea; Korea Inst Ocean Sci & Technol, Ocean Circulat & Climate Res Ctr, Busan 49111, South Korea; Natl Inst Meteorol Sci, Climate Res Div, Jeju 63568, South Korea; Kongju Natl Univ, Dept Atmospher Sci, Gongju 32588, South Korea; Gangneung Wonju Natl Univ, Dept Atmospher & Environm Sci, Kangnung 25457, South Korea; Chonnam Natl Univ, Dept Stat, Gwangju 61186, South Korea; Pohang Univ Sci & Technol, Div Environm Sci & Engn, Pohang 37673, South Korea Kim, Hyeong-Seog/F-4496-2010; Min, Seung-Ki/B-1431-2010; Park, JeongSoo/LVR-8624-2024; Byun, Young-Hwa/JCO-1048-2023; Park, Doo-Sun/U-9448-2019; BYUN, Young-Hwa/JCO-1048-2023; KIM, MAENG-KI/C-6454-2017 37117659000; 35487531500; 34972911900; 34568038900; 7406091975; 7201868003; 35171145500; 57192273006 dsrpark@knu.ac.kr;hyeongseog@kmou.ac.kr;mhkwon@kiost.ac.kr;yhbyun@korea.kr;mkkim@kongju.ac.kr;iuchung@gwnu.ac.kr;jspark@jnu.ac.kr;skmin@postech.ac.kr; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 9 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 0.55 2025-07-30 7 6 CMIP5; CMIP6; potential intensity; western North Pacific; South Korea CMIP5; CMIP6; Potential intensity; South korea; Western north pacific South Korea; Hurricanes; Mean square error; Storms; Thermodynamics; Tropics; Basin wide; CMIP6; Model evaluation; Pattern correlation; Performances evaluation; Potential intensity; South Korea; Thermodynamic conditions; Tropical cyclone; Western North Pacific; atmospheric dynamics; atmospheric modeling; CMIP; performance assessment; thermodynamics; tropical cyclone; Climate models English 2021 2021-09 10.3390/atmos12091214 바로가기 바로가기 바로가기 바로가기
Article Aerosol Properties within and above the Planetary Boundary Layer across the Korean Peninsula during December 2016 During December 2016, airborne aerosol measurements were taken at multiple heights across the Korean Peninsula to examine the vertical properties of aerosols. This study showed that aerosols above the planetary boundary layer (PBL) show similar concentrations and particle size distributions (PSDs), regardless of the relative locations in Korea. On the other hand, aerosols within the PBL differ depending on the geographical location, origin and path of the air mass. The concentrations are the highest in Seoul, followed by Gangneung, East Sea and the Yellow Sea. The known east-west aerosol gradient did not appear and the reasons are discussed in this paper. The study further shows that the aerosols of upwind regions affect the aerosols above the PBL, whereas aerosols in the PBL are affected by local sources and atmospheric conditions in addition to aerosols of upwind areas. Jung, Eunsil; Seo, Seongkyu; Chang, Ki-Ho; Yum, Seong-Soo; Heo, Bok-Haeng Kyungpook Natl Univ, Dept Adv Sci & Technol Convergence, Sangju 37224, South Korea; DigiQuay Co Ltd, Anyang 14058, Gyeonggi Do, South Korea; Natl Inst Meteorol Sci, Jeju 63568, South Korea; Yonsei Univ, Dept Atmospher Sci, Seoul 03722, South Korea; Korea Meteorol Adm, Seoul 07062, South Korea 55683061800; 57220870522; 36182839400; 7003842561; 6603253360 eunsiljung@knu.ac.kr;ggaru79@gmail.com;khchang@korea.kr;ssyum@yonsei.ac.kr;happyheo93@korea.kr; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 10 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 0.09 2025-07-30 1 1 vertical structure of aerosols; continental outflow regions; east-west aerosol gradient DISTRIBUTIONS; DUST; POLLUTION Continental outflow regions; East–west aerosol gradient; Vertical structure of aerosols Kangnung; Kangwon; Pacific Ocean; Sea of Japan; South Korea; Yellow Sea; Atmospheric aerosols; Atmospheric thermodynamics; Aerosol measurement; Aerosol properties; Continental outflow; Continental outflow region; East–west aerosol gradient; Particles-size distributions; Planetary boundary layers; Vertical structure of aerosol; Vertical structures; aerosol property; air mass; boundary layer; concentration (composition); particle size; size distribution; Particle size English 2021 2021-10 10.3390/atmos12101299 바로가기 바로가기 바로가기 바로가기
Article Future Projections and Uncertainty Assessment of Precipitation Extremes in the Korean Peninsula from the CMIP6 Ensemble with a Statistical Framework Scientists occasionally predict projected changes in extreme climate using multi-model ensemble methods that combine predictions from individual simulation models. To predict future changes in precipitation extremes in the Korean peninsula, we examined the observed data and 21 models of the Coupled Model Inter-Comparison Project Phase 6 (CMIP6) over East Asia. We applied generalized extreme value distribution (GEVD) to a series of annual maximum daily precipitation (AMP1) data. Multivariate bias-corrected simulation data under three shared socioeconomic pathway (SSP) scenarios-namely, SSP2-4.5, SSP3-7.0, and SSP5-8.5-were used. We employed a model weighting method that accounts for both performance and independence (PI-weighting). In calculating the PI-weights, two shape parameters should be determined, but usually, a perfect model test method requires a considerable amount of computing time. To address this problem, we suggest simple ways for selecting two shape parameters based on the chi-square statistic and entropy. Variance decomposition was applied to quantify the uncertainty of projecting the future AMP1. Return levels spanning over 20 and 50 years, as well as the return periods relative to the reference years (1973-2010), were estimated for three overlapping periods in the future, namely, period 1 (2021-2050), period 2 (2046-2075), and period 3 (2071-2100). From these analyses, we estimated that the relative increases in the observations for the spatial median 20-year return level will be approximately 18.4% in the SSP2-4.5, 25.9% in the SSP3-7.0, and 41.7% in the SSP5-8.5 scenarios, respectively, by the end of the 21st century. We predict that severe rainfall will be more prominent in the southern and central parts of the Korean peninsula. Shin, Yonggwan; Shin, Yire; Hong, Juyoung; Kim, Maeng-Ki; Byun, Young-Hwa; Boo, Kyung-On; Chung, Il-Ung; Park, Doo-Sun R.; Park, Jeong-Soo Chonnam Natl Univ, Dept Math & Stat, Gwangju 61186, South Korea; Kongju Natl Univ, Dept Atmospher Sci, Gongju 32588, South Korea; Natl Inst Meteorol Sci, Seogwipo 63568, South Korea; Gangneung Wonju Natl Univ, Dept Atmospher & Environm Sci, Kangnung 25457, South Korea; Kyungpook Natl Univ, Dept Earth Sci Educ, Daegu 41566, South Korea ; Park, Doo-Sun/U-9448-2019; BYUN, Young-Hwa/JCO-1048-2023; Park, JeongSoo/LVR-8624-2024; Byun, Young-Hwa/JCO-1048-2023; KIM, MAENG-KI/C-6454-2017 57195979725; 57201994621; 57226663206; 7406091975; 34568038900; 7003459696; 7201868003; 37117659000; 35171145500 syg.stat@gmail.com;shinyire@daum.net;hjy_stat@naver.com;mkkim@kongju.ac.kr;yhbyun@korea.kr;kyungon@korea.kr;iuchung@gwnu.ac.kr;dsrpark@knu.ac.kr;jspark@jnu.ac.kr; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 1 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 0.92 2025-07-30 11 11 climate change; Dirichlet distribution; exceedance probability; expected waiting time; generalized extreme value distribution; heavy rainfall; L-moment estimation; return period REGIONAL CLIMATE MODELS; EAST-ASIA; TEMPERATURE; INCREASE; EVENTS; TRENDS; INDEXES Climate change; Dirichlet distribution; Exceedance probability; Expected waiting time; Generalized extreme value distribution; Heavy rainfall; L-moment estimation; Return period Korea; Forecasting; Testing; Chi square statistic; Daily precipitations; Generalized extreme value distribution; Multi-model ensemble; Precipitation extremes; Statistical framework; Uncertainty assessment; Variance decomposition; CMIP; ensemble forecasting; error correction; extreme event; future prospect; multivariate analysis; performance assessment; precipitation intensity; probability; rainfall; uncertainty analysis; weather forecasting; Climate models English 2021 2021-01 10.3390/atmos12010097 바로가기 바로가기 바로가기 바로가기
Article High-Resolution Modeling of Mesoscale Circulation in the Atmospheric Boundary Layer over a Complex Coastal Area We evaluated the performance of the high-resolution (333 m) Weather Research and Forecasting (WRF) model in simulating the flow structure at a complex coastal site in Boseong, South Korea, on 15 July 2018, against observations obtained from a 300 m tower and radiosonde, and analyzed the model results to interpret the measurements. The study site is surrounded by mountains, valleys, and bays, and is adjacent to the South Sea; thus, it is influenced by terrain-forced flow and thermally driven circulation. The study day was characterized by the development of nighttime low-level wind maximum (LLWM) and daytime sea breeze under weak synoptic wind conditions. Although the WRF model simulated the onset and cessation of a sea breeze later than was observed, it showed good skill in reproducing the near-surface temperatures, wind vectors, and vertical profiles of potential temperatures and wind vectors in the atmospheric boundary layer at the study site. We analyzed the model results at 05:30 and 14:30 LST when the model's performance was good for wind. At 05:30 LST, hydraulic jump produced weak wind conditions below 300 m above ground level (AGL), and westerly down-valley flow developed near the surface, leading to an LLWM. At 14:30 LST, heating over land produced a thermal high over land at 1800 m AGL, counteracting the synoptic pressure gradient, and leading to weak wind conditions at this level. We performed three sensitivity simulations to examine the dependence of flow structure on the horizontal and vertical resolution. The results show that an early-morning hydraulic jump can be simulated by applying a high-resolution model in both the horizontal and vertical grids, and the simulated onset and cessation times of the sea breeze depend on the model's resolution. The dependence of flow structure on the model resolution has been discussed. Lim, Hee-Jeong; Lee, Young-Hee Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 41566, South Korea 55329559600; 56812706200 hjyim999@gmail.com;young@knu.ac.kr; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 12 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 0 2025-07-30 0 0 300 m tower; complex coastal area; high-resolution numerical simulation; sea breeze; nighttime low-level wind maximum (LLWM) SEA; WEATHER; TRANSPORT; BREEZES; TERRAIN; SHALLOW; SPAIN 300 m tower; Complex coastal area; High-resolution numerical simulation; Nighttime low-level wind maximum (LLWM); Sea breeze Boseong; South Cholla; South Korea; Atmospheric boundary layer; Atmospheric movements; Flow structure; Hydraulic jump; Landforms; Weather forecasting; 300 m tower; Coastal area; Complex coastal area; High-resolution models; High-resolution numerical simulation; Low-level winds; Nighttime low-level wind maximum; Performance; Sea-breeze; Wind conditions; atmospheric circulation; boundary layer; coastal zone; computer simulation; flow structure; radiosonde; sea breeze; weather forecasting; Coastal zones English 2021 2021-12 10.3390/atmos12121649 바로가기 바로가기 바로가기 바로가기
Article Impact of Tropical Cyclones on Inhabited Areas of the SWIO Basin at Present and Future Horizons. Part 1: Overview and Observing Component of the Research Project RENOVRISK-CYCLONE The international research program "ReNovRisk-CYCLONE" (RNR-CYC, 2017-2021) directly involves 20 partners from 5 countries of the south-west Indian-Ocean. It aims at improving the observation and modelling of tropical cyclones in the south-west Indian Ocean, as well as to foster regional cooperation and improve public policies adapted to present and future tropical cyclones risk in this cyclonic basin. This paper describes the structure and main objectives of this ambitious research project, with emphasis on its observing components, which allowed integrating numbers of innovative atmospheric and oceanic observations (sea-turtle borne and seismic data, unmanned airborne system, ocean gliders), as well as combining standard and original methods (radiosoundings and global navigation satellite system (GNSS) atmospheric soundings, seismic and in-situ swell sampling, drone and satellite imaging) to support research on tropical cyclones from the local to the basin-scale. Bousquet, Olivier; Barruol, Guilhem; Cordier, Emmanuel; Barthe, Christelle; Bielli, Soline; Calmer, Radiance; Rindraharisaona, Elisa; Roberts, Gregory; Tulet, Pierre; Amelie, Vincent; Fleischer-Dogley, Frauke; Mavume, Alberto; Zucule, Jonas; Zakariasy, Lova; Razafindradina, Bruno; Bonnardot, Francois; Singh, Manvendra; Lees, Edouard; Durand, Jonathan; Mekies, Dominique; Claeys, Marine; Pianezze, Joris; Thompson, Callum; Tsai, Chia-Lun; Husson, Romain; Mouche, Alexis; Ciccione, Stephane; Cattiaux, Julien; Chauvin, Fabrice; Marquestaut, Nicolas Univ Reunion, CNRS, Lab Atmosphere & Cyclones, UMR8105 LACy, F-97400 St Denis, France; Nelson Mandela Univ, Inst Coastal Marine Res CMR, ZA-6031 Port Elizabeth, South Africa; Univ Paris, CNRS, Inst Phys Globe Paris, F-75238 Paris, France; Univ Reunion, Observ Sci, UMS OSU R 3365, F-974007 St Denis, France; Univ Toulouse, CNRS, IRD, Lab Aerol,UT3, F-31400 Toulouse, France; Univ Colorado Boulder, Natl Snow & Ice Data Ctr NSIDC, Cooperat Inst Res Environm Sci, Boulder, CO 80304 USA; Univ La Reunion, Lab GeoSci Reunion LGSR, F-97400 St Denis, France; Univ Calif San Diego, Scripps Inst Oceanog, San Diego, CA 92093 USA; Univ Toulouse, CNRS, CNRM, Ctr Natl Rech Meteorol,UMR3589, F-31057 Toulouse, France; Seychelles Meteorol Author, Int Airport, Mahe 670311, Seychelles; Seychelles Isl Fdn, POB 853, Victoria 670311, Mahe, Seychelles; Eduardo Mondlane Univ, Fac Sci, Dept Phys, Maputo 257, Mozambique; Inst Nacl Meteorol INAM, Maputo 256, Mozambique; Inst Super Technol Antisiranana, BP 509, Antsiranana, Madagascar; Direct Interreg Meteo France Ocean Indien, F-97400 St Denis, France; Mauritius Oceanog Inst, Albion 95410, Mauritius; Kyungpook Natl Univ, Ctr Atmospher REmote Sensing CARE, Dept Astron & Atmospher Sci, Daegu 41566, South Korea; Collecte Localisat Satellites CLS, F-29280 Brest, France; CNRS, IFREMER, IRD, Lab Oceanog Phys & Spatiale,UBO, F-29280 Plouzane, France; Observ Tortues Marines La Reunion, Kelonia, F-97436 St Leu, France ; Tsai, Chia-Lun/AHI-4361-2022; Cordier, Emmanuel/N-1540-2013; Roberts, Greg/GWV-5653-2022; Barruol, Guilhem/A-7116-2008; Barruol, guilhem/M-8677-2019 8413672100; 6602857511; 42360920700; 22133430700; 7801624094; 55915364000; 55655002400; 7403401100; 55915046600; 41560959700; 34871737900; 37061335900; 57223116496; 6506452866; 57224163854; 25823700400; 58600214600; 57219112242; 57194105244; 57193991940; 56472428200; 56910274200; 57222057977; 55474132500; 55344362300; 8538711400; 15821751300; 26645901500; 7005501673; 57189991309 olivier.bousquet@meteo.fr;barruol@ipgp.fr;emmanuel.cordier@univ-reunion.fr;christelle.barthe@aero.obs-mip.fr;soline.bielli-bousquet@univ-reunion.fr;radiance.calmer@colorado.edu;elisa.rindraharisaona@univ-reunion.fr;greg.roberts@meteo.fr;pierre.tulet@aero.obs-mip.fr;v.amelie@meteo.gov.sc;ceo@sif.sc;amavume@yahoo.co.uk;jonas_z@inam.gov.mz;lova.zakariasy@ist-antsiranana.mg;hbrazafindradina@ist-antsiranana.mg;francois.bonnardot@meteo.fr;msingh@moi.intnet.mu;edouard.lees@meteo.fr;jonathan.durand@live.com;dominique.mekies@meteo.fr;marine.claeys@meteo.fr;joris.pianezze@univ-reunion.fr;callum-thompson@ucsb.edu;chialun@knu.ac.kr;rhusson@cls.fr;Alexis.Mouche@ifremer.fr;stephane.ciccione@museesreunion.re;julien.cattiaux@meteo.fr;fabrice.chauvin@meteo.fr;nicolas.marquestaut@univ-reunion.fr; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 5 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 1.48 2025-07-30 17 18 tropical cyclone; south-west Indian Ocean; gliders; unmanned airborne system; biologging; sea turtles; global satellite navigation system; ReNovRisk; numerical modelling; climate modelling; austral and cyclonic swells; seismic data OF-THE-ART; SECONDARY MICROSEISMS; POLEWARD MIGRATION; ATMOSPHERE-WAVE; INDIAN-OCEAN; SEA; PACIFIC; SENSITIVITY; SIMULATION; INTENSITY Austral and cyclonic swells; Biologging; Climate modelling; Gliders; Global satellite navigation system; Numerical modelling; ReNovRisk; Sea turtles; Seismic data; South-west Indian Ocean; Tropical cyclone; Unmanned airborne system Indian Ocean; Indian Ocean (Southwest); Cheloniidae; Testudines; Atmospheric structure; Global positioning system; Hurricanes; Risk assessment; Seismology; Tropics; Airborne systems; Atmospheric sounding; Global Navigation Satellite Systems; Inhabited areas; International researches; Regional cooperation; Satellite imaging; Tropical cyclone; airborne survey; climate modeling; GNSS; numerical model; research work; sampling; seismic data; tropical cyclone; turtle; unmanned vehicle; Storms English 2021 2021-05 10.3390/atmos12050544 바로가기 바로가기 바로가기 바로가기
Article Impact of Tropical Cyclones on Inhabited Areas of the SWIO Basin at Present and Future Horizons. Part 2: Modeling Component of the Research Program RENOVRISK-CYCLONE The ReNovRisk-Cyclone program aimed at developing an observation network in the south-west Indian ocean (SWIO) in close synergy with the implementation of numerical tools to model and analyze the impacts of tropical cyclones (TC) in the present and in a context of climate change. This paper addresses the modeling part of the program. First, a unique coupled system to simulate TCs in the SWIO is developed. The ocean-wave-atmosphere coupling is considered along with a coherent coupling between sea surface state, wind field, aerosol, microphysics, and radiation. This coupled system is illustrated through several simulations of TCs: the impact of air-sea flux parameterizations on the evolution of TC Fantala is examined, the full coupling developed during the program is illustrated on TC Idai, and the potential of novel observations like space-borne synthetic aperture radar and sea turtles to validate the atmosphere and ocean models is presented with TC Herold. Secondly, the evolution of cyclonic activity in the SWIO during the second half of the 21st century is assessed. It was addressed both using climate simulation and through the implementation of a pseudo global warming method in the high-resolution coupled modeling platform. Our results suggest that the Mascarene Archipelago should experience an increase of TC related hazards in the medium term. Barthe, Christelle; Bousquet, Olivier; Bielli, Soline; Tulet, Pierre; Pianezze, Joris; Claeys, Marine; Tsai, Chia-Lun; Thompson, Callum; Bonnardot, Francois; Chauvin, Fabrice; Cattiaux, Julien; Bouin, Marie-Noelle; Amelie, Vincent; Barruol, Guilhem; Calmer, Radiance; Ciccione, Stephane; Cordier, Emmanuel; Duong, Quoc-Phi; Durand, Jonathan; Fleischer-Dogley, Frauke; Husson, Romain; Lees, Edouard; Malardel, Sylvie; Marquestaut, Nicolas; Mavume, Alberto; Mekies, Dominique; Mouche, Alexis; Ravoson, Navalona Manitriniana; Razafindradina, Bruno; Rindraharisaona, Elisa; Roberts, Gregory; Singh, Manvendra; Zakariasy, Lova; Zucule, Jonas Univ La Reunion, CNRS, Lab Atmosphere & Cyclones, Meteo France, F-97400 St Denis, France; Univ Toulouse, CNRS, IRD, Lab Aerol,UT3, F-31400 Toulouse, France; Nelson Mandela Univ, Inst Coastal Marine Res, ZA-6031 Port Elizabeth, South Africa; Univ Toulouse, CNRS, CNRM, Meteo France, F-31057 Toulouse, France; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Ctr Atmospher REmote Sensing CARE, Daegu 41566, South Korea; Direct Interreg Meteo France Ocean Indien, F-97400 St Denis, France; Univ Brest, CNRS, IFREMER, Lab Oceanog Phys & Spatiale,IRD,IUFM, F-29280 Plouzane, France; Seychelles Meteorol Author, Mahe 670311, Seychelles; Univ Paris, CNRS, Inst Phys Globe Paris, F-75005 Paris, France; Univ Colorado, Cooperat Inst Res Environm Sci, Natl Snow & Ice Data Ctr NSIDC, Boulder, CO 80304 USA; Observ Tortues Marines La Reunion, Kelonia, F-97436 St Leu, France; Observ Sci Univers La Reunion, OSU R, UAR 3365, F-97400 St Denis, France; Seychelles Islands Fdn, Mahe 670311, Seychelles; Collecte Localisat Satellites CLS, F-29280 Brest, France; Eduardo Mondlane Univ, Fac Sci, Dept Phys, Maputo 257, Mozambique; Univ Antisiranana, Inst & Observ Geophys Antisiranana, Antananarivo 101, Madagascar; Inst Super Technol Antisiranana, Antsiranana 201, Madagascar; Univ La Reunion, Lab GeoSci Reunion LGSR, F-97400 St Denis, France; Univ Calif San Diego, Scripps Inst Oceanog, San Diego, CA 92103 USA; Mauritius Oceanog Inst, Albion 95410, Mauritius; Inst Nacl Meteorol INAM, Maputo 256, Mozambique Roberts, Greg/GWV-5653-2022; Barruol, Guilhem/A-7116-2008; Bouin, Marie-Noelle/AAV-1680-2021; Cordier, Emmanuel/N-1540-2013; Barruol, guilhem/M-8677-2019; Tsai, Chia-Lun/AHI-4361-2022 22133430700; 8413672100; 7801624094; 55915046600; 56910274200; 56472428200; 55474132500; 57222057977; 25823700400; 7005501673; 26645901500; 7003342377; 41560959700; 6602857511; 55915364000; 15821751300; 42360920700; 57223344911; 57194105244; 34871737900; 55344362300; 57219112242; 6506756436; 57189991309; 37061335900; 57193991940; 8538711400; 57224539320; 57224163854; 55655002400; 7403401100; 58600214600; 6506452866; 57223116496 christelle.barthe@aero.obs-mip.fr;olivier.bousquet@meteo.fr;soline.bielli-bousquet@univ-reunion.fr;pierre.tulet@aero.obs-mip.fr;pianezze.joris@gmail.com;marine.claeys@meteo.fr;chialun@knu.ac.kr;callum-thompson@ucsb.edu;francois.bonnardot@meteo.fr;fabrice.chauvin@meteo.fr;julien.cattiaux@meteo.fr;nbouin@ifremer.fr;v.amelie@meteo.gov.sc;barruol@ipgp.fr;radiance.calmer@colorado.edu;stephane.ciccione@museesreunion.re;emmanuel.cordier@univ-reunion.fr;quoc-phi.duong@meteo.fr;durand.jonathan.2@uqam.ca;ceo@sif.sc;rhusson@cls.fr;edouard.lees@meteo.fr;sylvie.malardel@meteo.fr;nicolas.marquestaut@univ-reunion.fr;alberto.mavume@uem.mz;dominique.mekies@meteo.fr;Alexis.Mouche@ifremer.fr;ravosonnaval3@gmail.com;hbrazafindradina@ist-antsiranana.mg;elisa.rindraharisaona@univ-reunion.fr;greg.roberts@meteo.fr;msingh@moi.intnet.mu;lova.zakariasy@ist-antsiranana.mg;jnzucule@gmail.com; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 6 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 0.55 2025-07-30 4 6 tropical cyclone; south-west Indian ocean; cloud-resolving model; ocean-wave-atmosphere coupling; climate modeling AIR-SEA MOMENTUM; HIGH WIND SPEEDS; BOUNDARY-LAYER; UPPER OCEAN; BULK PARAMETERIZATION; ATMOSPHERE; INTENSITY; SPRAY; SCHEME; FLUX Climate modeling; Cloud-resolving model; Ocean–wave–atmosphere coupling; South-west Indian ocean; Tropical cyclone Indian Ocean; Indian Ocean (Southwest); Cheloniidae; Global warming; Hurricanes; Storms; Surface waters; Synthetic aperture radar; Tropics; Climate simulation; Coherent coupling; Cyclonic activities; Model components; Observation networks; Pseudo-global warming methods; Research programs; Sea surface state; air-sea interaction; anticyclone; atmospheric modeling; climate change; climate modeling; future prospect; tropical cyclone; Climate models English 2021 2021-06 10.3390/atmos12060689 바로가기 바로가기 바로가기 바로가기
Article Non-Stationary Effects of the Arctic Oscillation and El Nino-Southern Oscillation on January Temperatures in Korea In recent decades, extremely cold winters have occurred repeatedly throughout the Northern Hemisphere, including the Korean Peninsula (hereafter, Korea). Typically, cold winter temperatures in Korea can be linked to the strengthening of the Siberian High (SH). Although previous studies have investigated the typical relationship between the SH and winter temperatures in Korea, this study uniquely focused on a change in the relationship, which reflects the influence of the Arctic Oscillation (AO) and El Nino-Southern Oscillation (ENSO). A significant change in the 15-year moving correlation between the SH and the surface air temperature average in Korea (K-tas) was observed in January. The correlation changed from -0.80 during 1971-1990 to -0.16 during 1991-2010. The mean sea-level pressure pattern regressed with the temperature, and a singular value decomposition analysis that incorporated the temperature and pressure supports that the negative high correlation during 1971-1990 was largely affected by AO. This connection with AO is substantiated by empirical orthogonal function (EOF) analysis with an upper-level geopotential height at 300 hPa. In the second mode of the EOF, the temperature and pressure patterns were primarily affected by ENSO during 1991-2010. Consequently, the interdecadal change in correlation between K-tas and the SH in January can be attributed to the dominant effect of AO from 1971-1990 and of ENSO from 1991-2010. Our results suggest that the relative importance of these factors in terms of the January climate in Korea has changed on a multidecadal scale. Yoon, Jae-Seung; Chung, Il-Ung; Shin, Ho-Jeong; Jang, Kunmn-Yeong; Kim, Maeng-Ki; Park, Jeong-Soo; Park, Doo-Sun R.; Boo, Kyung-On; Byun, Young-Hwa; Sung, Hyun-Min Gangneung Wonju Natl Univ, Nat Sci Res Inst, Kangnung 25457, South Korea; Gangneung Wonju Natl Univ, Dept Atmospher & Environm Sci, Kangnung 25457, South Korea; Kongju Natl Univ, Dept Atmospher Sci, Gongju 32588, South Korea; Chonnam Natl Univ, Dept Math & Stat, Gwangju 61186, South Korea; Kyungpook Natl Univ, Dept Earth Sci Educ, Daegu 41566, South Korea; Natl Inst Meteorol Sci, Seogwipo 63568, South Korea BYUN, Young-Hwa/JCO-1048-2023; Park, JeongSoo/LVR-8624-2024; KIM, MAENG-KI/C-6454-2017; Park, Doo-Sun/U-9448-2019; Byun, Young-Hwa/JCO-1048-2023 57223215889; 7201868003; 59881531300; 57223242576; 7406091975; 35171145500; 37117659000; 7003459696; 34568038900; 57210809003 jsvip13@naver.com;iuchung@gwnu.ac.kr;hojeong.shin@gmail.com;orangecoral@naver.com;mkkim@kongju.ac.kr;jspark@jnu.ac.kr;dsrpark@knu.ac.kr;kyungon@korea.kr;yhbyun@korea.kr;sunghm122@korea.kr; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 5 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 0 2025-07-30 1 1 extreme cold; arctic oscillation; El Nino-Southern Oscillation; Korean Peninsula; Siberian High ASIAN WINTER MONSOON; SURFACE AIR-TEMPERATURE; COLD EURASIA PATTERN; ENSO; VARIABILITY; BLOCKING; IMPACT; CIRCULATION; CLIMATE; LINKAGE Arctic oscillation; El Niño–Southern Oscillation; Extreme cold; Korean Peninsula; Siberian High Korea; Atmospheric pressure; Orthogonal functions; Sea level; Singular value decomposition; Empirical orthogonal function analysis; Geo-potential heights; Mean sea level pressures; Non-stationary effects; Northern Hemispheres; Singular value decomposition analysis; Surface air temperatures; Temperature and pressures; air temperature; air-sea interaction; Arctic Oscillation; El Nino-Southern Oscillation; paleoclimate; sea level pressure; Climatology English 2021 2021-05 10.3390/atmos12050538 바로가기 바로가기 바로가기 바로가기
Article Triterpenoids from Celastrus orbiculatus Thunb. inhibit RANKL-induced osteoclast formation and bone resorption via c-Fos signaling Fourteen triterpenes, lup-20(29)-ene-3 beta,6 beta-diol (1), betulin (2), lupeol caffeate (3), 3 beta-caffeoyloxylup-20(29)-en-6 alpha-ol (4), betulin-3 beta-yl-caffeate (5), 3 beta-trans-feruloylbetulin (6), betulinaldehyde 3-caffeate (7), 3-O-trans-caffeoylbetulinic acid (8), dammarenediol II 3-caffeate (9), 12-oleanene-3 beta,6 alpha-diol (10), 11 alpha-hydroxy-3 beta-amyrin (11), nivadiol (12), 29-hydroxyfriedelin (13), and celastrusin A (14) were isolated fromCelastrus orbiculatusThunb. and evaluated for their activity on receptor activator of nuclear factor kappa B ligand (RANKL)-induced osteoclast differentiation in bone marrow macrophages (BMMs). Compounds betulin (2), betulin-3 beta-yl-caffeate (5), 3 beta-trans-feruloylbetulin (6), and 3-O-trans-caffeoylbetulinic acid (8) significantly inhibited osteoclast formation in a dose-dependent manner. Among these, betulin-3 beta-yl-caffeate (5) exhibited the most potent inhibitory activity. We demonstrated that betulin-3 beta-yl-caffeate (5) suppressed F-actin-ring formation and bone resorption activity. At the molecular level, betulin-3 beta-yl-caffeate (5) inhibited RANK-induced expression of c-Fos and the induction of nuclear factor of activated T cells 1 (NFATc1), a key transcription factor for osteoclast formation, and it also downregulated mRNA expression of osteogenesis-associated marker genes including tartrate-resistant acid phosphatase (TRAP), dendritic cell-specific transmembrane protein (DC-STAMP), and matrix metalloprotein (MMP). These results indicate that betulin-3 beta-yl-caffeate (5) may be a promising candidate for the treatment of osteoclast-related diseases such as osteoporosis. [GRAPHICS] . Vu, Thi Oanh; Tran, Phuong Thao; Seo, Wonyoung; Lee, Jeong Hyung; Min, Byung Sun; Kim, Jeong Ah Kyungpook Natl Univ, Pharmaceut Sci Res Inst, Coll Pharm, Daegu 41566, South Korea; Kangwon Natl Univ, Dept Biochem, Coll Nat Sci, Chunchon 24341, Gangwon Do, South Korea; Daegu Catholic Univ, Coll Pharm, Drug Res & Dev Ctr, Gyongsan 38430, South Korea 57208535085; 56701990600; 57218325002; 26662839900; 55663638200; 24722570900 jkim6923@knu.ac.kr; JOURNAL OF NATURAL MEDICINES J NAT MED-TOKYO 1340-3443 1861-0293 75 1 SCIE CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY 2021 3.192 60.4 0.84 2025-07-30 9 8 Celastrus orbiculatus Thunb; Triterpenes; Osteoclastogenesis; RANK; c-Fos; NFATc1 LUPANE-TYPE TRITERPENES; C-13 NMR-SPECTRA; CAFFEOYL; ESTERS c-Fos; Celastrus orbiculatus Thunb; NFATc1; Osteoclastogenesis; RANK; Triterpenes Animals; Bone Resorption; Celastrus; Cell Differentiation; Male; Mice; Mice, Inbred ICR; Osteoclasts; Plant Extracts; Proto-Oncogene Proteins c-fos; RANK Ligand; Signal Transduction; Triterpenes; 11alpha hydroxy 3beta amyrin; 12 oleanene 3beta,6alpha diol; 29 hydroxyfriedelin; 3 o trans caffeoylbetulinic acid; 3beta caffeoyloxylup 20(29) en 6alpha ol; 3beta trans feruloylbetulin; acid phosphatase tartrate resistant isoenzyme; betulin; betulin 3beta yl caffeate; betulinaldehyde 3 caffeate; Celastrus orbiculatus extract; celastrusin A; dammarenediol II 3 caffeate; dendritic cell specific transmembrane protein; lup 20(29) ene 3beta,6beta diol; lupeol caffeate; matrix metalloproteinase; membrane protein; messenger RNA; nivadiol; osteoclast differentiation factor; plant extract; protein c fos; transcription factor NFAT; transcription factor NFATc1; triterpenoid; unclassified drug; osteoclast differentiation factor; plant extract; protein c fos; Tnfsf11 protein, mouse; triterpene; animal cell; animal tissue; anti osteoclastogenic effect; Article; bone marrow derived macrophage; Celastrus; Celastrus orbiculatus; cell differentiation; concentration response; controlled study; down regulation; drug activity; drug identification; drug isolation; drug potency; drug screening; drug structure; gene expression; in vitro study; intracellular signaling; male; marker gene; mouse; nonhuman; osteoclastogenesis; osteolysis; osteoporosis; plant stem; protein analysis; protein expression; protein induction; structure activity relation; animal; chemistry; drug effect; drug therapy; Institute for Cancer Research mouse; isolation and purification; metabolism; osteoclast; osteolysis; pathology; signal transduction English 2021 2021-01 10.1007/s11418-020-01444-3 바로가기 바로가기 바로가기 바로가기
Article Urban Effect on Sea-Breeze-Initiated Rainfall: A Case Study for Seoul Metropolitan Area We examined the sea-breeze-initiated rainfall in the Seoul Metropolitan area (SMA) on 6 July 2017 using the weather research and forecasting (WRF) model. The model captures the arrival of the sea breeze front (SBF), the development of afternoon rainfall in the SMA, and the location of the sea-breeze-initiated maximum rainfall in the northeastern SMA reasonably well but overestimates the subsequent rainfall. We conducted sensitivity tests to better understand the urban effect on the sea-breeze-initiated rainfall event. Through factor separation analysis, we first examined the explicit role of sea and urban effect on sea-breeze-initiated rainfall. The results show that the interaction of sea and urban effects cause rainfall in the northwest and northeast of the SMA, indicating that both urban heat island circulation (UHIC) and sea breeze play an important role in the study case's rainfall. We further examined the relative role of urban roughness and anthropogenic heat on the sea-breeze-initiated rainfall through factor separation analysis. Both anthropogenic heat and urban roughness play a role in increasing precipitation in the northeastern area of the SMA, with a larger contribution of anthropogenic heat than urban roughness. The relationship between low-level convergence at the SBF and urban factors is discussed. Choi, Yuna; Lee, Young-Hee Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 41566, South Korea 57221762910; 56812706200 zzzzz0415@naver.com;young@knu.ac.kr; ATMOSPHERE ATMOSPHERE-BASEL 2073-4433 12 11 SCIE ENVIRONMENTAL SCIENCES;METEOROLOGY & ATMOSPHERIC SCIENCES 2021 3.11 60.4 0.37 2025-07-30 4 5 afternoon rainfall; sea breeze; UHIC HEAT-ISLAND; NUMERICAL-MODEL; PRECIPITATION; URBANIZATION; CONVECTION; IMPACT; CIRCULATIONS; REGION; WINTER Afternoon rainfall; Sea breeze; UHIC Seoul [Seoul (ADS)]; Seoul [South Korea]; South Korea; Atmospheric temperature; Factor analysis; Weather forecasting; Afternoon rainfall; Anthropogenic heat; Case-studies; Sea-breeze; Sea-breeze fronts; Seoul metropolitan area; Separation analysis; Urban effect; Urban heat island circulation; Weather research and forecasting models; heat island; metropolitan area; precipitation (climatology); rainfall; sea breeze; Rain English 2021 2021-11 10.3390/atmos12111483 바로가기 바로가기 바로가기 바로가기
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eISSN Electronic ISSN. 전자 버전 저널에 부여되는 고유 식별번호입니다.
Volume 저널의 권(Volume) 번호입니다. 보통 연도별로 하나의 권이 부여됩니다.
Issue 저널의 호(Issue) 번호입니다. 한 권 내에서 여러 호로 나누어 출판되는 경우가 많습니다.
WoS Edition Web of Science의 에디션입니다. SCIE(Science Citation Index Expanded), SSCI(Social Sciences Citation Index), AHCI(Arts & Humanities Citation Index) 등으로 구분됩니다.
WoS Category Web of Science의 주제 분류 카테고리입니다. 저널과 논문이 속한 학문 분야를 나타냅니다.
JCR Year 해당 저널의 JCR(Journal Citation Reports) 지표가 산출된 연도입니다.
IF (Impact Factor) 저널 영향력 지수. 최근 2년간 발표된 논문이 해당 연도에 평균적으로 인용된 횟수를 나타냅니다. 저널의 학술적 영향력을 나타내는 대표적인 지표입니다.
JCR (%) 해당 카테고리에서 저널이 위치하는 상위 백분율입니다. 값이 낮을수록 우수한 저널임을 의미합니다 (예: 5%는 상위 5%를 의미).
FWCI Field-Weighted Citation Impact. 분야별 가중 인용 영향력 지수입니다. 논문이 받은 인용을 동일 분야, 동일 연도, 동일 문헌 유형의 평균과 비교한 값입니다. 1.0이 평균이며, 1.0보다 높으면 평균 이상의 인용을 받았음을 의미합니다.
FWCI UpdateDate FWCI 값이 마지막으로 업데이트된 날짜입니다. FWCI는 인용이 누적됨에 따라 주기적으로 업데이트됩니다.
WOS Citation Web of Science에서 집계된 해당 논문의 총 인용 횟수입니다.
SCOPUS Citation SCOPUS에서 집계된 해당 논문의 총 인용 횟수입니다.
Keywords (WoS) 저자가 논문에서 직접 지정한 키워드입니다. Web of Science에 등록된 저자 키워드 목록입니다.
KeywordsPlus (WoS) Web of Science에서 자동으로 추출한 추가 키워드입니다. 논문의 참고문헌 제목에서 자주 등장하는 단어들로 생성됩니다.
Keywords (SCOPUS) 저자가 논문에서 직접 지정한 키워드입니다. SCOPUS에 등록된 저자 키워드 목록입니다.
KeywordsPlus (SCOPUS) SCOPUS에서 자동으로 추출하거나 추가한 색인 키워드입니다.
Language 논문이 작성된 언어입니다. 대부분 English이며, 그 외 다양한 언어로 작성된 논문이 포함될 수 있습니다.
Publication Year 논문이 출판된 연도입니다.
Publication Date 논문의 정확한 출판 날짜입니다 (년-월-일 형식).
DOI Digital Object Identifier. 디지털 객체 식별자로, 논문을 고유하게 식별하는 영구적인 식별번호입니다. 이를 통해 논문의 온라인 위치를 찾을 수 있습니다.