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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Article | Surface anatomy and levator scapulae muscle injection A cadaveric investigation | Accurate detection of the levator scapulae muscle is critical for effective diagnostic and therapeutic interventions. The commonly used surface anatomy approach has not been validated and is less accurate than ultrasound-guided techniques. Therefore, we determined the needle insertion point for the levator scapulae using a new technique based on the anatomy of the scapula. This investigation used 15 fresh-frozen cadavers to explore the relationship between the acromial angle and medial tip of the scapular spine (O) of the scapular spine. Based on the x-axis (the distance [L] from Point O to point acromial angle) and the y-axis perpendicular to the x-axis passing through Point O, the barycentric coordinates were determined through the intersections of each axis and the superior angle of the scapula with the levator scapulae. Various ratios involving the established distance L) were ascertained, we compared the measurements and ratios between the male and female groups, and the accuracy of the new technique was compared with the conventional technique. The optimal site of the new technique was within 6 to 7% of distance L on the x-axis and 42 to 44% of distance L on the y-axis. This technique was significantly more accurate than the conventional technique (P = .006). Although ultrasound allows for accurate injections via real-time visualization, its unavailability in some cases highlights the importance of understanding surface anatomy landmarks. Our new technique, based on the anatomy of the scapula and relative measurements, is more accurate than the conventional technique. This should enable more precise detection of the levator scapulae for accurate and efficient diagnostic and therapeutic procedures. Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc. | Chang, So-Youn; Lim, Hee Young; Kim, Sang-Hyun; Choi, Jung-Woo; Nam, Yong-Seok; Lee, Jong In | Department of Rehabilitation Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Department of Rehabilitation Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Catholic Institute for Applied Anatomy, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Catholic Institute for Applied Anatomy, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Department of Anatomy, College of Medicine, Kyungpook National University, Daegu, South Korea; Department of Rehabilitation Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea | 57217848928; 58493242300; 55859127500; 58494570000; 36787618800; 57835047100 | ljikyh@catholic.ac.kr; | Medicine (United States) | MEDICINE | 0025-7974 | 1536-5964 | 103 | 25 | SCIE | MEDICINE, GENERAL & INTERNAL | 2024 | 1.4 | 43.2 | 0 | 2025-05-07 | 1 | cadaver; electromyography; injection; levator scapulae muscle; scapula; surface anatomy | Aged; Aged, 80 and over; Cadaver; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Muscle, Skeletal; Scapula; insulin; adult; aged; anatomical landmark; Article; cadaver; clinical article; controlled study; diagnostic accuracy; echography; female; human; human tissue; levator scapulae muscle; male; needle electromyography; scapula; surface property; cadaver; diagnostic imaging; intramuscular drug administration; middle aged; procedures; scapula; skeletal muscle; very elderly | English | Final | 2024 | 10.1097/md.0000000000038598 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Task-specific facial dystonia following COVID-19 infection: A case report | Rationale:During the coronavirus disease of 2019 (COVID-19) pandemic, various movement disorders associated with COVID-19 infection have been reported. However, the incidence of dystonia specifically associated with COVID-19 infection has been particularly rare.Patient concerns:A 43-year-old male patient presented to the movement disorders clinic with complaints of facial grimacing while chewing and experiencing spasms during nasal breathing. These symptoms appeared 2 weeks after he tested positive for COVID-19.Diagnoses:Based on normal diagnostic test results, including brain imaging and blood tests, it was concluded that task-specific facial dystonia following COVID-19 infection.Interventions:Despite treatment with clonazepam, trihexyphenidyl, and carbamazepine, his condition did not improve. Subsequently, botulinum toxin injections were administered to the affected facial muscles identified through video analysis.Outcomes:Botulinum toxin injections led to a significant improvement in the patient's symptoms.Lessons:Task-specific dystonia affecting the facial muscles, particularly induced by specific actions such as chewing and nasal breathing, is rare and may represent an atypical post-infectious manifestation of COVID-19. | Lee, Jong-Mok; Ko, Pan-Woo | Kyungpook Natl Univ, Sch Med, Dept Neurol, Daegu 700422, South Korea; Kyungpook Natl Univ Hosp, Dept Neurol, Daegu, South Korea | ; Lee, Jong-Mok/KVY-9550-2024 | 57192075673; 55543341200 | azulmar@gmail.com;panwoo.ko@gmail.com; | MEDICINE | MEDICINE | 0025-7974 | 1536-5964 | 103 | 37 | SCIE | MEDICINE, GENERAL & INTERNAL | 2024 | 1.4 | 43.2 | 0 | 2025-05-07 | 0 | 0 | botulinum; COVID-19; focal dystonia | MOVEMENT-DISORDERS | botulinum; COVID-19; focal dystonia | Adult; Botulinum Toxins, Type A; COVID-19; Dystonia, Focal, Task-Specific; Dystonic Disorders; Facial Muscles; Humans; Male; SARS-CoV-2; botulinum toxin A; carbamazepine; clonazepam; trihexyphenidyl; botulinum toxin A; adult; Article; blood analysis; case report; clinical article; conservative treatment; coronavirus disease 2019; face muscle; fatigue; fever; focal dystonia; human; male; mastication; muscle spasm; myalgia; neuroimaging; neurologic examination; nose breathing; nuclear magnetic resonance imaging; symptom; videorecording; complication; diagnosis; drug therapy; dystonic disorder; etiology; pathophysiology; Severe acute respiratory syndrome coronavirus 2 | English | 2024 | 2024-09-13 | 10.1097/md.0000000000039689 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Probing high scale seesaw and PBH generated dark matter via gravitational waves with multiple tilts | We propose a scenario where a high scale seesaw origin of light neutrino mass and gravitational dark matter (DM) in MeV-TeV ballpark originating from primordial black hole (PBH) evaporation can be simultaneously probed by future observations of stochastic gravitational wave (GW) background with multiple tilts or spectral breaks. A high scale breaking of an Abelian gauge symmetry ensures the dynamical origin of the seesaw scale while also leading to the formation of cosmic strings responsible for generating stochastic GW background. The requirement of a correct DM relic in this ballpark necessitates the inclusion of a diluter as PBH typically leads to DM overproduction. This leads to a second early matter dominated epoch after PBH evaporation due to the long-lived diluter. These two early matter dominated epochs, crucially connected to the DM relic, lead to multiple spectral breaks in the otherwise scale -invariant GW spectrum formed by cosmic strings. We find interesting correlations between DM mass and turning point frequencies of GW spectrum which are within reach of several near future experiments like LISA, BBO, ET, CE, etc. | Borah, Debasish; Das, Suruj Jyoti; Roshan, Rishav | Indian Inst Technol Guwahati, Dept Phys, Gauhati 781039, Assam, India; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea | ; Borah, Debasish/K-8411-2016 | 37005361300; 57219732669; 57211218592 | dborah@iitg.ac.in;suruj@iitg.ac.in;rishav.roshan@gmail.com; | NUCLEAR PHYSICS B | NUCL PHYS B | 0550-3213 | 1873-1562 | 1002 | SCIE | PHYSICS, PARTICLES & FIELDS | 2024 | 2.8 | 43.5 | 1.22 | 2025-05-07 | 4 | 3 | PRIMORDIAL BLACK-HOLES; NEUTRINO MASSES; RADIATION; MODELS | English | 2024 | 2024-05 | 10.1016/j.nuclphysb.2024.116528 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Analyzing the dynamics of complicated and uncomplicated appendicitis during the COVID-19 pandemic in Seoul, Korea: a multifaceted time series approach | OBJECTIVES: This study investigated the impact of the coronavirus disease 2019 (COVID-19) pandemic and associated control strategies on the incidence of appendicitis in Seoul, using data from 2018 to 2020 from Korea's National Health Insurance. METHODS: We analyzed records of total, complicated, and uncomplicated appendicitis cases, as well as the ratio of complicated to uncomplicated appendicitis, using natural spline and piecewise regression models to identify trends and breakpoints. Bayesian structural time-series (BSTS) models were used to evaluate the causal impact of social distancing on appendicitis incidences. RESULTS: The spline regression analysis indicated decreasing trends in both total and uncomplicated appendicitis cases. Conversely, the incidence of complicated appendicitis and the ratio of complicated to uncomplicated cases increased. Breakpoints for a decline in uncomplicated appendicitis and a rise in the ratio occurred at 31 weeks in 2020 (95% confidence interval [CI], 23.2 to 38.8) and at 33.9 weeks (95% CI, 28.3 to 39.6), respectively. The BSTS model demonstrated a 7.8% reduction in total appendicitis cases (95% credible interval [CrI],-12.1 to-3.3). It also showed a 17.4% decrease in uncomplicated cases (95% CrI,-22.2 to-12.3) and increases of 12.8% (95% CrI, 4.9 to 22.0) in complicated cases and 39.0% (95% CrI, 27.0 to 53.3) in the ratio of complicated to uncomplicated appendicitis. CONCLUSIONS: The COVID-19 pandemic resulted in a decrease in both total and uncomplicated appendicitis cases, while the number of complicated cases increased. Reduced medical visits likely accounted for these changes. Strategies are needed to manage changes in disease pathophysiology resulting from altered healthcare utilization during health crises. | Baek, Kiook; Park, Chulyong | Dongguk Univ, Dept Prevent Med, Coll Med, Gyeongju, South Korea; Dongguk Univ, Gyeongju Hosp, Dept Occupat & Environm Med, Gyeongju, South Korea; Kyungpook Natl Univ, Grad Sch, Dept Med, Daegu, South Korea; Yeungnam Univ Hosp, Dept Occupat & Environm Med, Daegu, South Korea; Yeungnam Univ, Coll Med, Dept Prevent Med & Publ Hlth, 170 Hyeonchung Ro, Daegu 42415, South Korea | 57190335322; 57190335503 | ironyong@gmail.com; | EPIDEMIOLOGY AND HEALTH | EPIDEMIOL HEALTH | 2092-7193 | 46 | SCIE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2024 | 2.2 | 43.6 | 0 | 2025-05-07 | 0 | 0 | COVID-19; Appendicitis; Appendectomy; Seoul | MANAGEMENT; DIAGNOSIS; SURGERY; IMPACT | Appendectomy; Appendicitis; COVID-19; Seoul | Adolescent; Adult; Aged; Appendicitis; Bayes Theorem; COVID-19; Female; Humans; Incidence; Male; Middle Aged; Republic of Korea; Seoul; Young Adult; acute appendicitis; adult; appendectomy; appendicitis; Article; bayesian structural time series; clinical evaluation; cohort analysis; complicated appendicitis; controlled study; coronavirus disease 2019; health behavior; health care access; human; incidence; major clinical study; molecular dynamics; national health insurance; pandemic; regression analysis; regression model; retrospective study; social distancing; South Korea; time series analysis; adolescent; aged; appendicitis; Bayes theorem; coronavirus disease 2019; epidemiology; female; male; middle aged; young adult | English | 2024 | 2024 | 10.4178/epih.e2024081 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Comparison of HIV characteristics across 3 datasets the Korea HIV/AIDS Cohort Study prospective, retrospective, and national reporting system | OBJECTIVES: The Korea HIV/AIDS Cohort Study has been conducted prospectively for 18 years. However, it faces limitations in representing the entire population of patients with human immunodeficiency virus (HIV) in Korea. To address these limitations and validate the study design, we analyzed characteristics across several HIV datasets. METHODS: We compared epidemiological and clinical characteristics from 3 datasets: the Korea HIV/AIDS Cohort Study (dataset 1, n=1,562), retrospective cohort data (dataset 2, n=2,665), and the national HIV reporting system of the Korea Disease Control and Prevention Agency (KDCA) (dataset 3, n=17,403). RESULTS: The demographic characteristics of age, sex, and age at HIV diagnosis did not differ significantly across datasets. However, dataset 3 contained a higher proportion of patients diagnosed after 2008 (69.5%) than the other datasets. Regarding transmission routes, same-sex contact accounted for a greater proportion of dataset 1 (59.8%) compared to datasets 2 (20.9%) and 3 (32.6%). The proportion of patients with CD4 T-cell counts below 200/mm3 3 at HIV diagnosis was higher in datasets 1 (39.4%) and 2 (33.3%) compared to dataset 3 (16.3%). Initial HIV viral load measurements were not obtained for dataset 3. CONCLUSIONS: The Korea HIV/AIDS Cohort Study demonstrated representativeness regarding the demographic characteristics of Korean patients. Of the sources, dataset 1 contained the most data on transmission routes. While the KDCA data encompassed all HIV patients, it lacked detailed clinical information. To improve the representativeness of the Korea HIV/AIDS Cohort Study, we propose expanding and revising the cohort design and enrolling more patients who have been recently diagnosed. | Choi, Yunsu; Choi, Jun; Choi, Bo; Park, Bo; Kim, Shin-Woo; Song, Joon; Kim, Jung; Kim, Sang | Hanyang Univ, Dept Prevent Med, Coll Med, 222 Wangshimni Ro, Seoul 04763, South Korea; Hanyang Univ, Inst Hlth & Soc, Seoul, South Korea; Yonsei Univ Coll Med, AIDS Res Inst, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Internal Med, Sch Med, Daegu, South Korea; Korea Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Div Infect Dis,Dept Internal Med, 222 Banpo Daero, Seoul 06591, South Korea | ; Kim, Jung/L-9791-2019; Choi, Yunsu/AAH-1260-2021; Choi, Jah/AAA-4835-2022 | 57195931031; 57791298700; 57236918400; 57217335056; 8710731500; 57214400146; 56657199800; 58305384100 | bychoi@hanyang.ac.kr;drksi@catholic.ac.kr; | EPIDEMIOLOGY AND HEALTH | EPIDEMIOL HEALTH | 2092-7193 | 46 | SCIE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2024 | 2.2 | 43.6 | 0.75 | 2025-05-07 | 1 | 1 | Cohort studies; Selection bias; Research design; HIV; Acquired immunodeficiency syndrome | BIAS | Acquired immunodeficiency syndrome; Cohort studies; HIV; Research design; Selection bias | Adult; Cohort Studies; Datasets as Topic; Female; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; Republic of Korea; Retrospective Studies; Young Adult; antiretrovirus agent; integrase inhibitor; nonnucleoside reverse transcriptase inhibitor; proteinase inhibitor; RNA directed DNA polymerase inhibitor; adult; aged; antiretroviral therapy; Article; CD4 lymphocyte count; clinical feature; cohort analysis; controlled study; data source; demographics; disease transmission; female; human; Human immunodeficiency virus; Human immunodeficiency virus infected patient; Human immunodeficiency virus infection; Korea; major clinical study; male; middle aged; public health service; retrospective study; sexual intercourse; study design; virus load; young adult; comparative study; epidemiology; Human immunodeficiency virus infection; information processing; prospective study; South Korea | English | 2024 | 2024 | 10.4178/epih.e2024055 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Prevalence and trends of cigarette smoking among adults with HIV infection compared with the general population in Korea | OBJECTIVES: This study compared the current smoking prevalence among adults with human immunodeficiency virus (HIV) infection to that of the general Korean population and analyzed changes in smoking prevalence and cessation rates from 2009 to 2020. METHODS: The study included a total of 10,980 adults with HIV infection who underwent a health screening examination (National Health Insurance Service-National Health Information Database; NHIS-NHID), 1,230 individuals with HIV infection who participated in the Korea HIV/AIDS Cohort (KoCosHIV), and 76,783 participants from the Korea National Health and Nutrition Examination Survey (KNHANES). We estimated the current smoking prevalence and the quit ratio, defined as the ratio of former smokers to ever-smokers. RESULTS: In the NHIS-NHID and KoCosHIV studies, the prevalence of current and former smoking among adults with HIV was 44.2% (95% confidence interval [CI], 43.2 to 45.1) and 15.6% (95% CI, 14.9 to 16.3), and 47.7% (95% CI, 43.7 to 51.8) and 16.9% (95% CI, 11.8 to 22.0), respectively. In the KNHANES, these rates were 22.5% and 18.1%, respectively. The standardized prevalence ratio of current smoking among adults with HIV was 1.76 in the NHIS-NHID and 1.97 in the KoCosHIV. Furthermore, the likelihood of quitting smoking was lower among adults with HIV than in the general population (NHIS-NHID: 26.1%; 95% CI, 25.0 to 27.1; KoCosHIV: 26.2%; 95% CI, 20.2 to 32.1; KNHANES: 44.6%; 95% CI, 44.5 to 44.6). Among HIV-positive adults, there was a 1.53% decline in the current smoking rate and a 2.86% increase in the quit ratio. CONCLUSIONS: Adults with HIV were more likely to smoke and less likely to quit smoking than the general adult population. Tobacco screening and cessation strategies should specifically target this population. | Park, Boyoung; Jang, Yoonyoung; Kim, Taehwa; Choi, Yunsu; Ahn, Kyoung Hwan; Kim, Jung Ho; Seong, Hye; Choi, Jun Yong; Kim, Hyo Youl; Song, Joon Young; Kim, Shin-Woo; Choi, Hee Jung; Park, Dae Won; Yoon, Young Kyung; Kim, Sang Il | Hanyang Univ, Coll Med, Dept Prevent Med, 222 Wangsimni Ro, Seoul 04763, South Korea; Hanyang Univ, Hanyang Inst Biosci & Biotechnol, Seoul, South Korea; Seoul Natl Univ, Dept Agr Econ & Rural Dev, Seoul, South Korea; Sungkyunkwan Univ, Dept Psychol, Seoul, South Korea; Yonsei Univ, Coll Med, Dept Internal Med, Div Infect Dis, Seoul, South Korea; Yonsei Univ, Coll Med, AIDS Res Inst, Seoul, South Korea; Korea Univ, Coll Med, Dept Internal Med, Div Infect Dis, Seoul, South Korea; Yonsei Univ, Wonju Coll Med, Dept Internal Med, Div Infect Dis, Wonju, South Korea; Kyungpook Natl Univ, Dept Internal Med, Sch Med, Taegu, South Korea; Ewha Womans Univ, Mokdong Hosp, Coll Med, Dept Internal Med, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Internal Med,Div Infect Dis, Seoul, South Korea | Choi, Jun/AEH-4018-2022; Kyung, Yoon/AAS-3428-2020 | 57217335056; 57215137959; 57927285900; 57195931031; 57832526400; 59087603100; 57193717138; 59657240700; 56819456800; 57214400146; 8710731500; 57217262202; 55724785200; 25947937900; 58305384100 | hayejine@hanyang.ac.kr; | EPIDEMIOLOGY AND HEALTH | EPIDEMIOL HEALTH | 2092-7193 | 46 | SCIE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2024 | 2.2 | 43.6 | 0 | 2025-05-07 | 0 | 0 | Human immunodeficiency virus; Tobacco smoking; Smoking cessation | NICOTINE METABOLISM; TOBACCO USE; INDIVIDUALS; VARENICLINE; EFFICACY; SMOKERS; PEOPLE; SAFETY | Human immunodeficiency virus; Smoking cessation; Tobacco smoking | Adult; Aged; Cigarette Smoking; Female; HIV Infections; Humans; Male; Middle Aged; Nutrition Surveys; Prevalence; Republic of Korea; Smoking Cessation; Young Adult; adult; aged; Article; cigarette smoking; cohort analysis; comparative study; controlled study; current smoker; data base; ex-smoker; female; human; Human immunodeficiency virus; Human immunodeficiency virus infection; infection prevention; Korea; major clinical study; male; mass screening; middle aged; never smoker; people by smoking status; population; prevalence; prevalence ratio; smoking cessation; standardization; young adult; epidemiology; nutrition; prevalence; South Korea | English | 2024 | 2024 | 10.4178/epih.e2024097 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Luminous blue carbon quantum dots employing Anisomeles indica (catmint) induce apoptotic signaling pathway in triple negative breast cancer (TNBC) cells | Herein, luminous blue carbon quantum dots (CDs) employing Anisomeles indica (Catmint) were reported with imaging, self-targeting, and therapeutic effects on triple-negative breast cancer (TNBC, MDA-MB-231) cells. The salient features of CDs generated from catmint are as follows: i) optical studies confirm CDs with excitation-dependent emission; ii) high-throughput characterization authenticates the formation of CDs with near-spherical shape with diameter ranging between 5 and 15 nm; iii) CDs induce cytotoxicity (3.22 +/- 0.64 mu g/ml) in triple-negative breast cancer (TNBC, MDA-MB-231) cells; iv) fluorescence microscopy demonstrates that CDs promote apoptosis by increasing reactive oxygen species (ROS) and decreasing mitochondrial membrane potential; v) CDs significantly up-regulate pro-apoptotic gene expression levels such as caspases-8/9/3. Finally, our work demonstrates that catmint-derived CDs are prospective nanotheranostics that augment cancer targeting and imaging. | Kumar, Ponnuchamy; Mahalakshmi, Marimuthu; Anitha, Selvaraj; Durgadevi, Sabapathi; Govarthanan, Muthusamy | Alagappa Univ, Dept Anim Hlth & Management, Food Chem & Mol Canc Biol, Karaikkudi 630003, Tamil Nadu, India; Kyungpook Natl Univ, Dept Environm Engn, Daegu, South Korea | Ponnuchamy, Kumar/D-3470-2013; Govarthanan, Muthusamy/C-1491-2014; Muthusamy, Govarthanan/C-1491-2014 | 55173720800; 59243579000; 57957509000; 57209773271; 54881927600 | kumarp@alagappauniversity.ac.in; | LUMINESCENCE | LUMINESCENCE | 1522-7235 | 1522-7243 | 39 | 8 | SCIE | CHEMISTRY, ANALYTICAL | 2024 | 3 | 43.7 | 0.5 | 2025-05-07 | 1 | 1 | apoptosis; bioimaging; carbon dots; catmint; fluorescence | LABEL-FREE DETECTION; GREEN-SYNTHESIS; SENSITIVE DETECTION; INHIBITION; FACILE; LUMINESCENCE; MERCURY(II); CONVERSION; MECHANISM; PRECURSOR | apoptosis; bioimaging; carbon dots; catmint; fluorescence | Antineoplastic Agents; Apoptosis; Carbon; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lamiaceae; Membrane Potential, Mitochondrial; Quantum Dots; Reactive Oxygen Species; Signal Transduction; Triple Negative Breast Neoplasms; Cancer cells; Carbon; Cell signaling; Diseases; Fluorescence; Fluorescence microscopy; Gene expression; Medical imaging; Mitochondria; Nanocrystals; Semiconductor quantum dots; antineoplastic agent; carbon; quantum dot; reactive oxygen metabolite; Anisomeles indica; Apoptotic signaling; Bio-imaging; Breast cancer cells; Carbon dots; Carbon quantum dots; Catmint; MDA-MB-231; Signalling pathways; Triple-negative breast cancers; apoptosis; cell survival; chemistry; drug effect; drug screening; drug therapy; human; Lamiaceae; metabolism; mitochondrial membrane potential; pathology; signal transduction; triple negative breast cancer; tumor cell line; Cell death | English | 2024 | 2024-08 | 10.1002/bio.4848 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Nonlinear Modeling of a Piezoelectric Actuator-Driven High-Speed Atomic Force Microscope Scanner Using a Variant DenseNet-Type Neural Network | Piezoelectric actuators (PEAs) are extensively used for scanning and positioning in scanning probe microscopy (SPM) due to their high precision, simple construction, and fast response. However, there are significant challenges for instrument designers due to their nonlinear properties. Nonlinear properties make precise and accurate control difficult in cases where position feedback sensors cannot be employed. However, the performance of PEA-driven scanners can be significantly improved without position feedback sensors if an accurate mathematical model with low computational costs is applied to reduce hysteresis and other nonlinear effects. Various methods have been proposed for modeling PEAs, but most of them have limitations in terms of their accuracy and computational efficiencies. In this research, we propose a variant DenseNet-type neural network (NN) model for modeling PEAs in an AFM scanner where position feedback sensors are not available. To improve the performance of this model, the mapping of the forward and backward directions is carried out separately. The experimental results successfully demonstrate the efficacy of the proposed model by reducing the relative root-mean-square (RMS) error to less than 0.1%. | Nguyen, Thi Thu; Otieno, Luke Oduor; Juma, Oyoo Michael; Nguyen, Thi Ngoc; Lee, Yong Joong | Kyungpook Natl Univ, Sch Mech Engn, 80 Daehakro, Daegu 41566, South Korea; Dedan Kimathi Univ Technol, Dept Elect & Elect Engn, Private Bag 10143, Dedan Kimathi, Kenya; Kyungpook Natl Univ, Dept Smart Mobil Engn, 80 Daehakro, Daegu 41566, South Korea | Otieno, Luke/KHW-8698-2024 | 58811314600; 57205578290; 58553964600; 57216184573; 57183248500 | thunt@knu.ac.kr;luke.otieno@dkut.ac.ke;michaeljuma@knu.ac.kr;2022226280@knu.ac.kr;yjlee76@knu.ac.kr; | ACTUATORS | ACTUATORS | 2076-0825 | 13 | 10 | SCIE | ENGINEERING, MECHANICAL;INSTRUMENTS & INSTRUMENTATION | 2024 | 2.3 | 43.7 | 0.45 | 2025-05-07 | 0 | 1 | high-speed atomic force microscopy (HS-AFM); hysteresis; nonlinear system; DenseNet-type neural network | COMPENSATION | DenseNet-type neural network; high-speed atomic force microscopy (HS-AFM); hysteresis; nonlinear system | English | 2024 | 2024-10 | 10.3390/act13100391 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Synthesis of Luminescent Copper Nanoparticles Using Couroupita guianensis Flower Extract: Evaluation of Antibacterial and Anticancer Activities | The biosynthesis of nanoparticles is a crucial research area aimed at developing innovative, cost-effective, and eco-friendly synthesis techniques for various applications. Herein, we synthesized copper oxide nanoparticles (CuNPs) using Couroupita guianensis flower extract via a simple green synthesis method. These green CuNPs demonstrate promising antimicrobial activity and anticancer activity against A549 nonsmall cell lung cancer (NSCLC) cells. We comprehensively characterized the CuNPs using UV spectrum, XRD, FTIR, SEM, and EDS analyses. The antibacterial and anticancerous performance is attributed to their spherical-like morphology, which enhances effective interaction with bacterial and cancer cells. Moreover, CuNPs proved effective in inactivating Escherichia coli, achieving 2%, 52%, and 99% inactivation at 0, 30, and 60 min, respectively, and Listeria monocytogenes, achieving 1%, 48%, and 98% inactivation at 0, 30, and 60 min, respectively, under visible light. Furthermore, the CuNPs exhibited significant anticancer activity against A549 NSCLC cells, achieving cell viability reductions of 10%, 30%, 50%, 70%, 83%, and 91% at concentrations of 25, 50, 100, 150, 200, and 250 mu g/mL, respectively. The green synthesized CuNPs demonstrate their potential in biomedical applications. | Saritha, P.; Arunprakash, S.; Srinivasan, P.; Selvankumar, T.; Aldawood, Saad; Kim, Woong; Velu, Manikandan; Song, Kwang Soup | Arignar Anna Govt Arts Coll, Dept Bot, Namakkal, Tamil Nadu, India; Saveetha Univ, Saveetha Dent Coll & Hosp, Saveetha Inst Med & Tech Sci, Dept Biomat, Chennai, India; Saveetha Univ, Saveetha Med Coll & Hosp, Saveetha Inst Med & Tech Sci, Ctr Global Hlth Res, Chennai, India; King Saud Univ, Coll Sci, Dept Phys & Astron, Riyadh, Saudi Arabia; Kyungpook Natl Univ, Dept Environm Engn, Daegu, South Korea; Kumoh Natl Inst Technol, Dept Med IT Convergence Engn, Gumi, South Korea | ; Thangaswamy, Selvankumar/M-5777-2015; Aldawood, Saad/F-9334-2018; Selvankumar, Thangaswamy/W-1639-2019 | 59351276700; 54881927900; 57190217427; 24485017700; 56116892200; 55581636400; 57194505368; 7401740642 | arunbot2003@rediffmail.com; | LUMINESCENCE | LUMINESCENCE | 1522-7235 | 1522-7243 | 39 | 10 | SCIE | CHEMISTRY, ANALYTICAL | 2024 | 3 | 43.7 | 2.5 | 2025-05-07 | 3 | 8 | anticancer activities; bacteria inactivation; Couroupita guianensis; flower extract; photonic | ASSISTED GREEN SYNTHESIS; ORANGE II DYE; DEGRADATION | anticancer activities; bacteria inactivation; Couroupita guianensis; flower extract; photonic | A549 Cells; Anti-Bacterial Agents; Antineoplastic Agents; Cell Proliferation; Cell Survival; Copper; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Escherichia coli; Flowers; Green Chemistry Technology; Humans; Listeria monocytogenes; Luminescence; Metal Nanoparticles; Microbial Sensitivity Tests; Plant Extracts; Fourier transform infrared spectroscopy; Green Synthesis; Listeria; Lung cancer; Metal nanoparticles; Near infrared spectroscopy; antiinfective agent; antineoplastic agent; copper; metal nanoparticle; plant extract; Anti-bacterial activity; Anticancer activities; Bacteria inactivation; Copper nanoparticles; Couroupita guianensis; Flower extracts; Lung cancer cells; Non small cell lung cancer; Research areas; Synthesised; A-549 cell line; cell proliferation; cell survival; chemistry; dose response; drug effect; drug screening; Escherichia coli; flower; green chemistry; human; Listeria monocytogenes; luminescence; microbial sensitivity test; synthesis; Escherichia coli | English | 2024 | 2024-10 | 10.1002/bio.4913 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Diagnostic performance of procalcitonin for bacterial infection in severe alcoholic hepatitis compared with C-reactive protein | BackgroundSevere alcoholic hepatitis is a catastrophic disease with a mortality rate of up to 35-50% at 30 days. Bacterial infection is an important prognostic factor in patients with severe alcoholic hepatitis, but it is difficult to detect the presence of infection immediately. Procalcitonin (PCT) is a well-known inflammatory marker that can detect bacterial infections in various diseases early. Therefore, we aimed to evaluate the diagnostic accuracy of PCT for bacterial infection in severe alcoholic hepatitis.MethodsWe prospectively enrolled patients with severe alcoholic hepatitis, defined as modified Maddrey's Discriminant Function >= 32, from 10 medical centers. At admission, we performed an initial evaluation including physical examination, laboratory test, radiology, blood and urine culture, PCT, and C-reactive protein (CRP). We compared the receiver operating characteristic (ROC) curves of PCT and CRP for bacterial infection, systemic inflammatory response syndrome (SIRS), and sepsis among total patients.ResultsA total of 108 patients with severe alcoholic hepatitis were enrolled. The number of bacterial infections, SIRS, and sepsis were 31 (28.7%), 41 (38.0%), and 19 (17.6%), respectively. The patients with bacterial infection had significantly higher MELD scores (24.0 vs. 15.0), PCT levels (1.5 vs. 0.4 ng/mL), and CRP levels (4.9 vs. 2.5 mg/dL) compared to those without bacterial infection. The area under the ROC curve (AUROC) of PCT vs. CRP for bacterial infection was 0.752 and 0.655, respectively (P = 0.113). The AUROC of PCT vs. CRP for SIRS was 0.699 and 0.662, respectively (P = 0.490). The AUROC of PCT vs. CRP for sepsis was 0.780 and 0.630, respectively (P = 0.027).ConclusionsAmong patients with severe alcoholic hepatitis, PCT showed a trend of superior diagnostic performance in the early detection of bacterial infection and sepsis compared to CRP. Although PCT might have better potential to diagnose sepsis in the setting of severe alcoholic hepatitis, it is necessary to find more reliable diagnostic markers. | Kang, Min Kyu; Lee, Yu Rim; Park, Soo Young; Seo, Kwang Il; Lee, Sang Soo; Kim, Byung Seok; Song, Jeong Eun; Yoon, Jun Sik; Hong, Young Mi; Yoon, Ki Tae; Chung, Woo Jin; Park, Seung Ha; Kim, Eunju; Jun, Kyung Ran; Park, Jung Gil; Baek, Yang-Hyun; Heo, Nae-Yun | Yeungnam Univ, Coll Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kosin Univ, Coll Med, Gospel Hosp, Dept Internal Med, Busan, South Korea; Gyeongsang Natl Univ, Changwon Hosp, Sch Med, Dept Internal Med, Chang Won, South Korea; Daegu Catholic Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Inje Univ, Busan Paik Hosp, Coll Med, Dept Internal Med, Busan, South Korea; Pusan Natl Univ, Coll Med, Yangsan Hosp, Dept Internal Med, Yangsan, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Internal Med, Daegu, South Korea; Inje Univ, Coll Med, Haeundae Paik Hosp, Dept Internal Med, Busan, South Korea; Inje Univ, Haeundae Paik Hosp, Dept Lab Med, Coll Med, Busan, South Korea; Dong A Univ, Coll Med, Dept Internal Med, Busan, South Korea | Kang, Min Kyu/AHI-4762-2022; Heo, Nae-Yun/LUY-9667-2024; Lee, Sang/P-7617-2019; Seo, Kwang Il/IUP-1034-2023; KIM, BYUNGSEOK/KDR-6539-2024 | 59142854300; 57194094753; 57191674344; 57194628377; 36183832300; 55974276800; 57189097150; 57195953972; 56405847000; 14820137300; 55741230500; 35171133100; 57216035574; 8934779400; 57216816399; 15844799800; 14022750600 | p100100@dau.ac.kr;H00175@paik.ac.kr; | BMC GASTROENTEROLOGY | BMC GASTROENTEROL | 1471-230X | 24 | 1 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 2.6 | 43.9 | 0 | 2025-05-07 | 0 | 1 | Alcoholic hepatitis; Bacterial infection; Sepsis; Procalcitonin; C-reactive protein | SYSTEMIC INFLAMMATORY RESPONSE; ORGAN FAILURE; SERUM; CORTICOSTEROIDS; PREDNISOLONE; DEFINITIONS; THERAPY; MARKERS; SEPSIS | Alcoholic hepatitis; Bacterial infection; C-reactive protein; Procalcitonin; Sepsis | Adult; Bacterial Infections; Biomarkers; C-Reactive Protein; Female; Hepatitis, Alcoholic; Humans; Male; Middle Aged; Procalcitonin; Prospective Studies; ROC Curve; Sensitivity and Specificity; Sepsis; Severity of Illness Index; Systemic Inflammatory Response Syndrome; alanine aminotransferase; albumin; aspartate aminotransferase; bilirubin; C reactive protein; creatinine; gamma glutamyltransferase; hemoglobin; procalcitonin; biological marker; C reactive protein; procalcitonin; Acinetobacter; acute pyelonephritis; adult; alcohol consumption; alcoholic hepatitis; Article; Aspergillus; assessment of humans; bacteremia; bacterial infection; bacterial peritonitis; body height; body temperature; body weight; Campylobacter; cellulitis; chemiluminescence immunoassay; cholecystitis; clinical outcome; clinical trial; Clostridioides difficile; Clostridium difficile infection; colitis; controlled study; diagnostic accuracy; diagnostic procedure; diagnostic test accuracy study; electrochemiluminescence immunoassay; empyema; Enterococcus; enzyme linked fluorescent assay; Escherichia coli; female; human; immunoturbidimetry; international normalized ratio; Klebsiella pneumoniae; latex agglutination test; leukocyte count; major clinical study; male; middle aged; Model For End Stage Liver Disease Score; modified Maddreys discriminant function score; multicenter study; multiple organ failure; pneumonia; predictive value; prospective study; quick Sequential Organ Failure Assessment Score; receiver operating characteristic; sensitivity and specificity; sepsis; Sequential Organ Failure Assessment Score; severe alcoholic hepatitis; Staphylococcus; Streptococcus agalactiae; systemic inflammatory response syndrome; urea nitrogen blood level; urinary tract infection; bacterial infection; blood; comparative study; complication; diagnosis; metabolism; receiver operating characteristic; severity of illness index | English | 2024 | 2024-11-25 | 10.1186/s12876-024-03519-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Reading of small bowel capsule endoscopy after frame reduction using an artificial intelligence algorithm | Objectives Poorly visualized images that appear during small bowel capsule endoscopy (SBCE) can confuse the interpretation of small bowel lesions and increase the physician's workload. Using a validated artificial intelligence (AI) algorithm that can evaluate the mucosal visualization, we aimed to assess whether SBCE reading after the removal of poorly visualized images could affect the diagnosis of SBCE. Methods A study was conducted to analyze 90 SBCE cases in which a small bowel examination was completed. Two experienced endoscopists alternately performed two types of readings. They used the AI algorithm to remove poorly visualized images for the frame reduction reading (AI user group) and conducted whole frame reading without AI (AI non-user group) for the same patient. A poorly visualized image was defined as an image with < 50% mucosal visualization. The study outcomes were diagnostic concordance and reading time between the two groups. The SBCE diagnosis was classified as Crohn's disease, bleeding, polyp, angiodysplasia, and nonspecific finding. Results The final SBCE diagnoses between the two groups showed statistically significant diagnostic concordance (k = 0.954, p < 0.001). The mean number of lesion images was 3008.5 +/- 9964.9 in the AI non-user group and 1401.7 +/- 4811.3 in the AI user group. There were no cases in which lesions were completely removed. Compared with the AI non-user group (120.9 min), the reading time was reduced by 35.6% in the AI user group (77.9 min). Conclusions SBCE reading after reducing poorly visualized frames using the AI algorithm did not have a negative effect on the final diagnosis. SBCE reading method integrated with frame reduction and mucosal visualization evaluation will help improve AI-assisted SBCE interpretation. | Oh, Dong Jun; Hwang, Youngbae; Kim, Sang Hoon; Nam, Ji Hyung; Jung, Min Kyu; Lim, Yun Jeong | Dongguk Univ, Dongguk Univ Ilsan Hosp, Coll Med, Dept Internal Med, 27 Dongguk Ro, Goyang 10326, South Korea; Chungbuk Natl Univ, Dept Elect Engn, Cheongju, South Korea; Chung Ang Univ, Gwangmyeong Hosp, Coll Med, Dept Internal Med, Gwangmyeong, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Gastroenterol & Hepatol, Daegu, South Korea | KANG, MIN KYU/ACI-8824-2022; Kim, Soo-Jin/P-2677-2014 | 57203029221; 7402311392; 57215900945; 42361607200; 56783168100; 56501161800 | drlimyj@gmail.com; | BMC GASTROENTEROLOGY | BMC GASTROENTEROL | 1471-230X | 24 | 1 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2024 | 2.6 | 43.9 | 2.68 | 2025-05-07 | 5 | 6 | Artificial intelligence; Capsule endoscopy; Frame reduction; Mucosal visualization | DEVICE-ASSISTED ENTEROSCOPY; DISORDERS EUROPEAN-SOCIETY; DIAGNOSIS | Artificial intelligence; Capsule endoscopy; Frame reduction; Mucosal visualization | Artificial Intelligence; Capsule Endoscopy; Colonic Diseases; Crohn Disease; Humans; Intestine, Small; Retrospective Studies; algorithm; angiodysplasia; Article; artificial intelligence; capsule endoscopy; clinical examination; clinical outcome; controlled study; Crohn disease; endoscopist; frame reduction reading; gastrointestinal endoscopy; human; image analysis; image processing; imaging and display; intestinal bleeding; intestine injury; major clinical study; small bowel capsule endoscopy; small bowel polyp; vascular lesion; workload; artificial intelligence; colon disease; Crohn disease; diagnostic imaging; pathology; retrospective study; small intestine | English | 2024 | 2024-02-22 | 10.1186/s12876-024-03156-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Stochastic seismic acoustic impedance inversion via a Markov-chain Monte Carlo method using a single GPU card | Seismic acoustic impedance inversion plays an important role in understanding subsurface structures and obtaining subsurface properties. The stochastic approach is one of the methods used for impedance inversion, and it aims to produce more reliable results by accounting for modeling uncertainty. Stochastic inversion represents the uncertainty of a subsurface model as a probability distribution and uses this distribution to estimate model parameters. In this study, seismic acoustic impedance inversion was performed using a Markov-chain Monte Carlo approach, which is a sampling method used in the stochastic process. Utilizing Bayesian inference based on prior information and observed data, we implemented acceptance probabilities and performed acoustic impedance inversion for field data through iterative calculations. We employed a single GPU card to execute the inversion algorithm and conducted a comparative analysis with the results obtained using a cluster composed of multiple CPU cores. Through a computational speed analysis, the efficiency of the algorithm using a GPU was verified, while uncertainty analysis was employed for algorithm validation. Through these analyses, we confirmed the feasibility of applying our developed GPU algorithm to tasks that require the inversion of extensive data, such as high-resolution seismic exploration and CO2 storage monitoring. | Moon, Seokjoon; Cho, Yongchae; Sim, Yongwoo; Lee, Donghak; Jun, Hyunggu | Seoul Natl Univ, Dept Energy Syst Engn, Seoul 08826, South Korea; Seoul Natl Univ, Res Inst Energy & Resources, Dept Energy Syst Engn, 1 Gwanak Ro, Seoul 08826, South Korea; Collaborat Computat Link, 122 Gwanak Ro, Seoul 08791, South Korea; Kyungpook Natl Univ, Dept Geol, 80 Daehak Ro, Daegu 41566, South Korea | Jun, Hyunggu/ABT-7172-2022; Cho, Yongchae/AAA-7647-2021 | 58711144900; 55513719100; 58986633800; 58986459900; 56048061400 | yc.cho@snu.ac.kr; | JOURNAL OF APPLIED GEOPHYSICS | J APPL GEOPHYS | 0926-9851 | 1879-1859 | 224 | SCIE | GEOSCIENCES, MULTIDISCIPLINARY;MINING & MINERAL PROCESSING | 2024 | 2.1 | 43.9 | 1.26 | 2025-05-07 | 3 | 3 | Stochastic inversion; Markov-chain Monte Carlo; GPU acceleration; Speedup analysis | UNCERTAINTY QUANTIFICATION | GPU acceleration; Markov-chain Monte Carlo; Speedup analysis; Stochastic inversion | Acoustic impedance; Bayesian networks; Clustering algorithms; Computational efficiency; Digital storage; Graphics processing unit; Inference engines; Iterative methods; Markov processes; Monte Carlo methods; Seismic prospecting; Seismology; Stochastic models; Stochastic systems; Uncertainty analysis; Acoustic impedance inversion; GPU accelerations; Markov chain Monte Carlo; Markov chain Monte Carlo method; Markov Chain Monte-Carlo; Speedup analyse; Stochastic inversion; Stochastics; Subsurface properties; Subsurface structures; algorithm; carbon dioxide; carbon storage; data inversion; Markov chain; Monte Carlo analysis; seismic data; stochasticity; Probability distributions | English | 2024 | 2024-05 | 10.1016/j.jappgeo.2024.105357 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The IAHS Science for Solutions decade, with Hydrology Engaging Local People IN one Global world (HELPING) | The new scientific decade (2023-2032) of the International Association of Hydrological Sciences (IAHS) aims at searching for sustainable solutions to undesired water conditions - whether it be too little, too much or too polluted. Many of the current issues originate from global change, while solutions to problems must embrace local understanding and context. The decade will explore the current water crises by searching for actionable knowledge within three themes: global and local interactions, sustainable solutions and innovative cross-cutting methods. We capitalise on previous IAHS Scientific Decades shaping a trilogy; from Hydrological Predictions (PUB) to Change and Interdisciplinarity (Panta Rhei) to Solutions (HELPING). The vision is to solve fundamental water-related environmental and societal problems by engaging with other disciplines and local stakeholders. The decade endorses mutual learning and co-creation to progress towards UN sustainable development goals. Hence, HELPING is a vehicle for putting science in action, driven by scientists working on local hydrology in coordination with local, regional, and global processes. | Arheimer, Berit; Cudennec, Christophe; Castellarin, Attilio; Grimaldi, Salvatore; Heal, Kate V.; Lupton, Claire; Sarkar, Archana; Tian, Fuqiang; Kileshye Onema, Jean-Marie; Archfield, Stacey; Bloeschl, Guenter; Chaffe, Pedro L. Borges; Croke, Barry F. W.; Dembele, Moctar; Leong, Chris; Mijic, Ana; Mosquera, Giovanny M.; Nlend, Bertil; Olusola, Adeyemi O.; Polo, Maria J.; Sandells, Melody; Sheffield, Justin; van Hateren, Theresa C.; Shafiei, Mojtaba; Adla, Soham; Agarwal, Ankit; Aguilar, Cristina; Andersson, Jafet C. M.; Andraos, Cynthia; Andreu, Ana; Avanzi, Francesco; Bart, Ryan R.; Bartosova, Alena; Batelaan, Okke; Bennett, James C.; Bertola, Miriam; Bezak, Nejc; Boekee, Judith; Bogaard, Thom; Booij, Martijn J.; Brigode, Pierre; Buytaert, Wouter; Bziava, Konstantine; Castelli, Giulio; Castro, Cyndi V.; Ceperley, Natalie C.; Chidepudi, Sivarama K. R.; Chiew, Francis H. S.; Chun, Kwok P.; Dagnew, Addisu G.; Dekongmen, B. W.; Del Jesus, Manuel; Dezetter, Alain; Do Nascimento Batista, Jose A.; Doble, Rebecca C.; Dogulu, Nilay; Eekhout, Joris P. C.; Elci, Alper; Elenius, Maria; Finger, David C.; Fiori, Aldo; Fischer, Svenja; Foerster, Kristian; Ganora, Daniele; Gargouri Ellouze, Emna; Ghoreishi, Mohammad; Harvey, Natasha; Hrachowitz, Markus; Jampani, Mahesh; Jaramillo, Fernando; Jongen, Harro J.; Kareem, Kola Y.; Khan, Usman T.; Khatami, Sina; Kingston, Daniel G.; Koren, Gerbrand; Krause, Stefan; Kreibich, Heidi; Lerat, Julien; Liu, Junguo; Liu, Suxia; Madruga de Brito, Mariana; Mahe, Gil; Makurira, Hodson; Mazzoglio, Paola; Merheb, Mohammad; Mishra, Ashish; Mohammad, Hiba; Montanari, Alberto; Mujere, Never; Nabavi, Ehsan; Nkwasa, Albert; Orduna Alegria, Maria E.; Orieschnig, Christina; Ovcharuk, Valeriya; Palmate, Santosh S.; Pande, Saket; Pandey, Shachi; Papacharalampous, Georgia; Pechlivanidis, Ilias; Penny, Gopal; Pimentel, Rafael; Post, David A.; Prieto, Cristina; Razavi, Saman; Salazar-Galan, Sergio; Sankaran Namboothiri, Adarsh; Santos, Pedro P.; Savenije, Hubert; Shanono, Nura J.; Sharma, Ashutosh; Sivapalan, Murugesu; Smagulov, Zhanibek; Szolgay, Jan; Teng, Jin; Teuling, Adriaan J.; Teutschbein, Claudia; Tyralis, Hristos; van Griensven, Ann; van Schalkwyk, Andries J.; van Tiel, Marit; Viglione, Alberto; Volpi, Elena; Wagener, Thorsten; Wang, Xiaojun; Wang-Erlandsson, Lan; Wens, Marthe; Xia, Jun | Swedish Meteorol & Hydrol Inst SMHI, Hydrol Res, Norrkoping, Sweden; INRAE, Inst Agro, SAS, Rennes, France; Univ Bologna, Dept Civil Chem Environm & Mat Engn DICAM, Bologna, Italy; Univ Tuscia, DIBAF Dept, Viterbo, Italy; Univ Edinburgh, Sch GeoSci, Edinburgh, Midlothian, Scotland; IAHS Ltd, UKCEH Wallingford, Wallingford, Oxon, England; Natl Inst Hydrol, Roorkee, Uttar Pradesh, India; Tsinghua Univ, Dept Hydraul Engn, State Key Lab Hydrosci & Engn, Beijing, Peoples R China; North West Univ, WaterNet, Potchefstroom, South Africa; Univ Lubumbashi, Sch Ind Engineers, Lubumbashi, DEM REP CONGO; US Geol Survey, Water Mission Area, 959 Natl Ctr, Reston, VA 22092 USA; Vienna Univ Technol, Inst Hydraul Engn & Water Resources Management, Vienna, Austria; Univ Fed Santa Catarina, Dept Sanit & Environm Engn, Florianopolis, SC, Brazil; Australian Natl Univ, Inst Water Futures, Canberra, ACT, Australia; Int Water Management Inst IWMI, Accra, Ghana; Res Inst Humanity & Nat, Linkage, Kyoto, Japan; Imperial Coll London, Dept Civil & Environm Engn, London, England; Pontificia Univ Catolica Peru PUCP, Dept Ingn, Lima, Peru; Univ Douala, Dept Earth Sci, Fac Sci, Douala, Cameroon; York Univ, Fac Environm & Urban Change, Toronto, ON, Canada; Univ Cordoba, Andalusian Inst Earth Syst Res, DAUCO, Cordoba, Spain; Northumbria Univ, Dept Geog & Environm Sci, Newcastle Upon Tyne, Tyne & Wear, England; Univ Southampton, Sch Geog & Environm Sci, Southampton, Hants, England; Acacia Water, Gouda, Netherlands; Norwegian Inst Bioecon Res, Div Environm & Nat Resources, As, Norway; Delft Univ Technol, Dept Water Management, Delft, Netherlands; Indian Inst Technol, Dept Hydrol, Roorkee 247667, Uttar Pradesh, India; St Joseph Univ, Fac Engn, ESIB, Beirut, Lebanon; CIMA Res Fdn, Savona, Italy; Univ Calif Merced, Sierra Nevada Res Inst, Merced, CA USA; Flinders Univ S Australia, Coll Sci & Engn, Adelaide, SA, Australia; CSIRO, Canberra, ACT, Australia; Univ Ljubljana, Fac Civil & Geodet Engn, Ljubljana, Slovenia; Univ Twente, Fac Engn Technol, Water Engn & Management, Enschede, Netherlands; Univ Rennes, CNRS, Geosci Rennes UMR 6118, Rennes, France; Georgian Tech Univ, Dept Hydraul Engn & Civil Construct, Fac Civil Engn, Atlanta, GA USA; Univ Florence, Dept Agr Food Environm & Forestry DAGRI, Florence, Italy; Univ Geneva, UNESCO Chair Hydropolit, Geneva, Switzerland; Univ Geneva, Inst Environm Sci ISE, Geneva, Switzerland; Natl Ctr Atmospher Res, POB 3000, Boulder, CO 80307 USA; Univ Bern, Inst Geog, Hydrol, Bern, Switzerland; Univ Rouen Normandie, CNRS, M2C UMR 6143, UNICAEN, Rouen, France; Bur Rech Geol & Minieres, Orleans, France; Univ West England, Dept Geog, Bristol, Avon, England; Millennium Water Alliance, Water Sanitat & Hyg, Bahir Dar, Ethiopia; Ho Tech Univ, Dept Agr Engn, Ho, Ghana; Univ Cantabria, Inst Hidraul Ambiental, Santander, Spain; Univ Montpellier, CNRS, HydroSci Montpellier, IRD,IMT Ales, Montpellier, France; Univ Estadual Campinas, Dept Water Resources, Campinas, Brazil; World Meteorol Org WMO, Hydrol Water Resources & Cryosphere Branch, Geneva, Switzerland; CEBAS CSIC, Soil & Water Conservat Res Grp, El Puntal, Spain; Dokuz Eylul Univ, Dept Environm Engn, Izmir, Turkiye; Reykjavik Univ, Dept Engn, Reykjavik, Iceland; Roma Tre Univ, DICITA, Rome, Italy; Wageningen Univ & Res, Hydrol & Environm Hydraul, Wageningen, Netherlands; Weihenstephan Triesdorf Univ Appl Sci, Inst Ecol & Landscape, Freising Weihenstephan, Germany; Politecn Torino, Dept Environm Land & Infrastruct Engn DIATI, Turin, Italy; Univ Tunis El Manar, Natl Engn Sch Tunis, Civil Engn Dept, Tunis, Tunisia; Univ Saskatchewan, Global Inst Water Secur, Dept Civil Geol & Environm Engn, Sch Environm & Sustainabil, Saskatoon, SK, Canada; Australian Natl Univ, Inst Water Futures, Canberra, ACT, Australia; Australian Natl Univ, Fenner Sch Environm & Soc, Canberra, ACT, Australia; Int Water Management Inst IWMI, Colombo, Sri Lanka; Stockholm Univ, Stockholm, Sweden; Wageningen Univ, Meteorol & Air Qual, Wageningen, Netherlands; Kyungpook Natl Univ, Dept Adv Sci & Technol Convergence, Sangju, Gyeongbuk, South Korea; York Univ, Civil Engn, York, N Yorkshire, England; Univ Melbourne, Dept Infrastruct Engn, Parkville, Vic, Australia; Univ Otago, Sch Geog, Dunedin, New Zealand; Univ Utrecht, Copernicus Inst Sustainable Dev, Utrecht, Netherlands; Univ Birmingham, Sch Geog Earth & Environm Sci, Birmingham, W Midlands, England; GFZ German Res Ctr Geosci, Sect Hydrol, Potsdam, Germany; North China Univ Water Resources & Elect Power, Henan Prov Key Lab Hydrosphere & Watershed Water, Zhengzhou, Henan, Peoples R China; Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Key Lab Water Cycle & Related Land Surface Proc, Beijing, Peoples R China; Univ Chinese Acad Sci, Coll Resources & Environm, Sino Danish Coll, Beijing, Peoples R China; UFZ Helmholtz Ctr Environm Res, Dept Urban & Environm Sociol, D-04318 Leipzig, Germany; Univ Zimbabwe, Dept Construct & Civil Engn, Harare, Zimbabwe; Univ Brescia, Dept Civil Environm Architectural Engn & Math DIC, Brescia, Italy; Univ Zimbabwe, Dept Geog Geospatial Sci & Earth Observat, Harare, Zimbabwe; Australian Natl Univ, Responsible Innovat Lab, Australian Natl Ctr Publ Awareness Sci, Canberra, ACT, Australia; Vrije Univ Brussel, Dept Water & Climate, Brussels, Belgium; Int Inst Appl Syst Anal IIASA, Laxenburg, Austria; Univ Kansas, Kansas Geol Survey, Lawrence, KS 66045 USA; Univ Montpellier, Inst Agro, AgroParisTech, UMR G Eau,IRD,BRGM,CIRAD,INRAE, Montpellier, France; Odessa State Environm Univ, Hydrometeorol Inst, Odessa, Ukraine; Texas A&M Univ, Dept Biol & Agr Engn, El Paso AgriLife Res & Extens Ctr, College Stn, TX 77843 USA; Forest Res Inst, Forest Ecol & Climate Change, Dehra Dun, Uttarakhand, India; Natl Tech Univ Athens, Dept Topog, Athens, Greece; Environm Def Fund, Climate Resilient Water Syst, New York, NY USA; Univ Pablo de Olavide, Agroecosyst Hist Lab, Seville, Spain; TKM Coll Engn, Dept Civil Engn, Peroor, India; Univ Lisbon, Inst Geog & Spatial Planning, Associate Lab TERRA, Ctr Geog Studies, Lisbon, Portugal; Bayero Univ Kano, Dept Agr & Environm Engn, Kano, Nigeria; Univ Illinois, Dept Civil & Environm Engn, Champaign, IL USA; Inst Geog & Water Secur JSC, Water Resources Lab, Alma Ata, Kazakhstan; Slovak Univ Technol Bratislava, Dept Land & Water Resources Management, Bratislava, Slovakia; Uppsala Univ, Dept Earth Sci, Uppsala, Sweden; Swiss Fed Inst Technol, Lab Hydraul Hydrol & Glaciol VAW, Zurich, Switzerland; Swiss Fed Inst Forest Snow & Landscape Res WSL, Birmensdorf, Switzerland; Univ Potsdam, Inst Environm Sci & Geog, Potsdam, Germany; Nanjing Hydraul Res Inst, Natl Key Lab Water Disaster Prevent, Nanjing 210029, Peoples R China; Minist Water Resources, Res Ctr Climate Change, Nanjing 210029, Peoples R China; Stockholm Univ, Stockholm Resilience Ctr, Stockholm, Sweden; Vrije Univ Amsterdam, Inst Environm Studies, Amsterdam, Netherlands; Wuhan Univ, Res Inst Water Secur RIWS, Wuhan, Peoples R China | ; Santos, Pedro/D-7076-2014; Castro, Cyndi/AAY-8693-2020; Doble, Rebecca/B-8293-2008; Papacharalampous, Georgia/A-6617-2019; Jaramillo, Fernando/T-4713-2017; Kileshye Onema, Jean-Marie/MEP-5323-2025; Pande, Saket/A-2671-2009; Teuling, Ryan/D-2318-2014; Ghoreishi, Mohammad/AAZ-5010-2021; Orieschnig, Christina/ISB-1670-2023; Hamed, Mohammed/AAW-7463-2021; Kreibich, Heidi/HNR-9624-2023; Castellarin, Attilio/B-2508-2009; Bennett, James/C-8456-2013; Elçi, Alper/B-6664-2009; OrdunaAlegria, MariaElena/LKJ-0728-2024; Madruga de Brito, Mariana/E-7069-2017; Razavi, Saman/L-3725-2013; Sharma, Ashutosh/AAM-3049-2020; Post, David/A-9563-2011; Gargouri-Ellouze, Emna/R-7289-2016; Fiori, Aldo/A-2321-2010; Dezetter, Alain/J-8367-2016; Viglione, Alberto/M-4860-2017; Palmate, Santosh/O-9594-2018; Polo, Maria/L-8018-2014; Wens, Marthe/HLP-9895-2023; Bziava, Konstantine/AAO-5821-2021; Mazzoglio, Paola/HJP-5919-2023; Cudennec, Christophe/A-6952-2008; Jampani, Mahesh/S-8682-2018; Szolgay, Jan/AAC-5336-2019; Penny, Gopal/AAA-6895-2021; Mosquera, Giovanny/G-9319-2017; Wang-Erlandsson, Lan/V-5999-2019; Andreu, Ana/AAS-6098-2020; Khatami, Sina/E-3157-2012; Tyralis, Hristos/A-1480-2019; Ceperley, Natalie/F-3962-2016; Batista, José/NLN-7163-2025; van Tiel, Marit/CAA-1282-2022; Smagulov, Zhanibek/GYR-3184-2022; Jongen, Harro/ABZ-5462-2022; Adla, Soham/JXM-9154-2024; Dembélé, Moctar/P-7609-2019; Wagener, Thorsten/C-2062-2008; Chiew, Francis/A-9743-2011; Fischer, Svenja/I-9496-2019; Chaffe, Pedro/AAW-3900-2020; MISHRA, ASHISH/IAI-2611-2023; Lerat, Julien/C-4168-2012; Pimentel, Rafael/L-3238-2015; Batelaan, Okke/C-7306-2008; Savenije, H/AAS-1883-2020; Kingston, Daniel/ABC-2010-2021; van Griensven, Ann/M-4312-2013; Montanari, Alberto/B-5427-2009; Merheb, Mohammad/ADE-3037-2022; Buytaert, Wouter/D-9912-2011; Chun, Kwok/P-5782-2018; Brigode, Pierre/B-7481-2014; Ovcharuk, Valeriya/H-3953-2018; Olusola, Adeyemi/GQP-2042-2022; Eekhout, Joris/B-3146-2016; Bezak, Nejc/AFN-5317-2022; Croke, Barry/A-2275-2008; Finger, David/AFS-6986-2022; Andersson, Jafet/S-1129-2019; Nabavi, Ehsan/JFS-5800-2023; Dagnew, Addisu/AAE-9406-2020; Krause, Stefan/C-4351-2008; Kareem, Kola/AAQ-8968-2021; Dogulu, Nilay/H-8995-2019; Dekongmen, Benjamin Wullobayi/ABD-4693-2021; Bartosova, Alena/HSC-1368-2023; Prieto, Cristina/Y-9015-2019; Teutschbein, Claudia/P-5504-2014; Salazar-Galán, Sergio/Y-7484-2019; Castelli, Giulio/O-2592-2018; Avanzi, Francesco/G-8504-2014; Teng, Jin/A-8611-2011; Andraos, Cynthia/MZR-2628-2025; Chidepudi, Sivarama Krishna Reddy/HKW-3667-2023; Tian, Fuqiang/M-9958-2013; del Jesus, Manuel/E-8860-2012; Pechlivanidis, Ilias/AAC-6979-2019; Booij, Martijn/C-7753-2011; Sheffield, Justin/A-6388-2008 | 6701506575; 6603925381; 6603944928; 7005688502; 6701649697; 57209714896; 23973661500; 7103096618; 14631996600; 16678344600; 7004862771; 25639362700; 6701639025; 57190374023; 57196057761; 55354024800; 56414720200; 57201492011; 43261635900; 58868399800; 56115779300; 7102636633; 57211514826; 56348783700; 57210748261; 57196058350; 36674489000; 35228445500; 57339256700; 7006379945; 55631580800; 36102162900; 6603371464; 6701427325; 53663198100; 57204612134; 56019823000; 57945556500; 6601952412; 55950028700; 55248276100; 6506727482; 57220834781; 57194380100; 57216828868; 53981054900; 58043373300; 7004309625; 26666468500; 57222050481; 57242344200; 55144771700; 6603339836; 57994944000; 14420829100; 56734560800; 55437615400; 6603631991; 55195589500; 7003771163; 57200342073; 56537601000; 36988392200; 36979163700; 25027530500; 57222525030; 58223294100; 8682392100; 37665642000; 55583329700; 57463043400; 57217253943; 36185269300; 56740552100; 13205714100; 57204166652; 36971236700; 8146124100; 22735054100; 57200122300; 35226162700; 57189252152; 57763818500; 14626695500; 57217288568; 57216192833; 57216964593; 59249250900; 55765625400; 37047648300; 57189073126; 57217202296; 57212452298; 57226299805; 14050737300; 57188994237; 16068916900; 57202809670; 57193572430; 35786333200; 55935648500; 55796340500; 7103012572; 57204790998; 39062138000; 57312689100; 59248796200; 56499523100; 7003427413; 57163937600; 57204024490; 56223343300; 58283187400; 23398364000; 35184226100; 8839237600; 36477558800; 36160730400; 59249094500; 59249094600; 57200419069; 25824453700; 8221993300; 8363445500; 36469504300; 56035883000; 57220588368; 57211494148 | berit.arheimer@smhi.se; | HYDROLOGICAL SCIENCES JOURNAL | HYDROLOG SCI J | 0262-6667 | 2150-3435 | 69 | 11 | SCIE | WATER RESOURCES | 2024 | 2.5 | 43.9 | 21.34 | 2025-05-07 | 11 | 12 | Water crises; holistic solutions; co-creation; transdisciplinary; local context; Anthropocene | EARTH SYSTEM SCIENCE; WATER CHALLENGES; KNOWLEDGE; SERVICES; SOCIETY; EUROPE; FUTURE | Anthropocene; co-creation; holistic solutions; local context; transdisciplinary; Water crises | English | 2024 | 2024-08-17 | 10.1080/02626667.2024.2355202 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Exploration of MELK as a downstream of Del-1 and druggable targets in triple-negative breast cancer | PurposeIn our previous study, Developmental endothelial locus-1 (Del-1) was a promising predictive marker for breast cancer. However, the downstream targets of Del-1 remain unknown. Here, we sought to discover a druggable target downstream of Del-1 and investigate the mechanism by which it regulates the course of breast cancer.MethodsTo investigate Del-1 downregulation effect on breast cancer, we performed transcriptome analysis using RNA sequencing of Del-1 knockdowned MDA-MB-231 cell line Plus, to investigate the expression of Del-1 and Maternal embryonic leucine zipper kinase (MELK), mRNA levels in eight different triple-Negative Breast Cancer (TNBC) cell lines were analyzed. High-throughput sequencing was performed on total RNA isolated. OTS167 was used for MELK inhibition. The effects of MELK on cell proliferation and invasion were determined using the MTT and Matrigel transwell assays. Furthermore, we examined MELK expression in breast cancer tissue.ResultsDel-1 and MELK mRNA expression levels were significantly higher in the TNBC cell lines, MDA-MB-468, HCC-1806, and MBA-MB-231. Knocking down Del-1 with siRNA in HCC-1806 and MBA-MB-231 cells significantly decreased MELK expression and thus suggested a possible relationship between Del-1 and MELK. In MDA-MB-468 cells, a basal-like 1 TNBC cell line, OTS167 significantly inhibited breast cancer cell proliferation and promoted cell apoptosis. To further investigate the relationship between Del-1 and MELK, dual inhibition of both Del-1 and MELK was performed, which significantly reduced the viability of MDA-MB-468 and MBA-MB-231 cells.ConclusionWe found that MELK acts downstream of Del-1 and is a promising druggable target, especially in basal-like and mesenchymal stem-like subtype. | Lee, In Hee; Lee, Soo Jung; Kang, Byeongju; Lee, Jeeyeon; Jung, Jin Hyang; Park, Ho Yong; Park, Ji-Young; Park, Nora Jee-Young; Kim, Eun Ae; Kang, Jieun; Chae, Yee Soo | Kyungpook Natl Univ, Kyungpook Natl Univ, Sch Med, Dept Oncol Hematol,Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Breast & Thyroid Surg, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Daegu, South Korea | ; PARK, JUN-YOUNG/P-5981-2015; Park, Young-Bae/J-5490-2012 | 57191881516; 57203597252; 57279815300; 37079213100; 57209310173; 56564377200; 57210160197; 57226185359; 55241586600; 57212252058; 57190793908 | yschae@knu.ac.kr; | BREAST CANCER RESEARCH AND TREATMENT | BREAST CANCER RES TR | 0167-6806 | 1573-7217 | 205 | 1 | SCIE | ONCOLOGY | 2024 | 3 | 44.0 | 0.47 | 2025-05-07 | 1 | 1 | Breast cancer; Del-1; MELK; TNBC | DEVELOPMENTAL ENDOTHELIAL LOCUS-1; REGULATOR; BIOMARKER; GROWTH | Breast cancer; Del-1; MELK; TNBC | Apoptosis; Calcium-Binding Proteins; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Protein Serine-Threonine Kinases; Triple Negative Breast Neoplasms; developmental endothelial locusc 1; maternal embryonic leucine zipper kinase; matrigel; messenger RNA; protein serine threonine kinase; scleroprotein; small interfering RNA; unclassified drug; calcium binding protein; cell adhesion molecule; EDIL3 protein, human; MELK protein, human; protein serine threonine kinase; apoptosis; Article; breast cancer; cancer tissue; cell cycle arrest; cell proliferation; controlled study; down regulation; downstream processing; female; gene expression profiling; high throughput sequencing; human; human cell; human tissue; liver cell carcinoma; major clinical study; MDA-MB-231 cell line; MDA-MB-468 cell line; mesenchyme; molecularly targeted therapy; mRNA expression level; protein expression; RNA sequencing; transcriptomics; triple negative breast cancer; cell motion; cell proliferation; gene expression regulation; genetics; metabolism; pathology; triple negative breast cancer; tumor cell line | English | 2024 | 2024-05 | 10.1007/s10549-023-07198-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | ReadGuard: Integrated SSD Management for Priority-Aware Read Performance Differentiation | When multiple apps with different I/O priorities share a high-performance SSD, it is important to differentiate the I/O QoS level based on the I/O priority of each app. In this paper, we study how a modern flash-based SSD should be designed to support priority-aware read performance differentiation. From an in-depth evaluation study using 3D TLC SSDs, we observed that existing FTLs have several weaknesses that need to be improved for better read performance differentiation. In order to overcome the existing FTL weaknesses, we propose ReadGuard, , a novel priority-aware SSD management technique that enables an FTL to manage its blocks in a fully read-latency-aware fashion. ReadGuard leverages a new read-latency-centric block quality marker that can accurately distinguish the read latency of a block and ensures that higher-quality blocks are used for higher-priority apps. ReadGuard extends an existing suspend/resume technique to handle collisions among reads. Our experimental results show that a ReadGuard-enabled SSD is effective in supporting differentiated read performance in modern 3D flash SSDs. | Chun, Myoungjun; Kim, Myungsuk; Lee, Dusol; Park, Jisuno; Kim, Jihong | Seoul Natl Univ, Seoul, South Korea; Kyungpook Natl Univ, Daegu, South Korea; POSTECH, Pohang, South Korea | 57211568029; 57194859467; 57219877309; 56095781900; 57202122647 | mjchun@davinci.snu.ac.kr;ms.kim@knu.ac.kr;dslee@davinci.snu.ac.kr;jisungpark@postech.ac.kr;jihong@davinci.snu.ac.kr; | ACM TRANSACTIONS ON STORAGE | ACM T STORAGE | 1553-3077 | 1553-3093 | 20 | 4 | SCIE | COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, SOFTWARE ENGINEERING | 2024 | 2.6 | 44.1 | 0.37 | 2025-05-07 | 0 | 1 | flash memory; read latency optimization; I/O priority | INDUCED LEAKAGE CURRENT; NAND FLASH; DATA RETENTION | Additional Key Words and PhrasesSSD; flash memory; I/O priority; read latency optimization | Memory management; Additional key word and phrasesssd; Depth evaluations; Evaluation study; I/O priority; Key words; Latency optimizations; Performance; Read latencies; Read latency optimization; Read performance; Flash-based SSDs | English | 2024 | 2024-11 | 10.1145/3676884 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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