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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Real Scarless Transoral Robotic Thyroidectomy Using Three Ports Without Axillary Incision | Introduction: Conventional transoral robotic thyroidectomy (TORT) requires an axillary incision and additional flap dissection. This study aimed to outline the first ever experiences with TORT using three ports without axillary incision and compare the results between three-port and four-port TORT. Materials and Methods: A total of 100 consecutive patients were enrolled. The study sample comprised 47 patients who underwent four-port TORT from November 2016 to June 2017, and 53 patients who underwent three-port TORT from September 2018 to June 2019. The indication of the three-port TORT was the anterior/posterior length of the thyroid Results: Operative time (minutes) was shorter in the three-port group (166.3 +/- 35.4 versus 138.5 +/- 34.4, P = .005). Hospital stay (days) was also shorter in the three-port group (3.8 +/- 0.4 versus 2.4 +/- 0.6, P = .003). TORT using three ports yielded a higher cosmetic satisfaction (3.68 +/- 0.52 versus 3.89 +/- 0.30, P = .002). Postoperative complications, level of calcium, parathyroid hormone, and pain were not significantly different between the groups. Conclusions: Our study showed that three-port TORT was associated with a shorter operative time, hospital stay, and excellent cosmesis than the conventional four-port option. In conclusion, TORT using three ports is a comparable and an effective operation method as a real scarless operation. | Kim, Wan Wook; Park, Chan Sub; Lee, Jeeyeon; Jung, Jin Hyang; Park, Ho Yong; Tufano, Ralph P. | Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea; Johns Hopkins Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Baltimore, MD 21205 USA | PARK, JUN-YOUNG/P-5981-2015 | 26023273400; 57208483662; 37079213100; 57209310173; 56564377200; 7006462546 | kww1324@naver.com; | JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES | J LAPAROENDOSC ADV S | 1092-6429 | 1557-9034 | 30 | 11 | SCIE | SURGERY | 2020 | 1.878 | 66.6 | 0.89 | 2025-06-25 | 10 | 10 | thyroidectomy; robotic; scarless thyroidectomy; transoral | ENDOSCOPIC THYROIDECTOMY; SERIES | robotic; scarless thyroidectomy; thyroidectomy; transoral | Adult; Female; Humans; Length of Stay; Male; Middle Aged; Minimally Invasive Surgical Procedures; Neck Dissection; Operative Time; Postoperative Complications; Postoperative Period; Retrospective Studies; Robotic Surgical Procedures; Thyroid Neoplasms; Thyroidectomy; antibiotic agent; calcium; paracetamol; parathyroid hormone; tramadol; adult; antibiotic prophylaxis; Article; calcium blood level; controlled study; esthetics; female; fistula; human; hypocalcemia; incision; length of stay; major clinical study; male; operation duration; parathyroid hormone blood level; patient satisfaction; perforation; postoperative complication; postoperative infection; postoperative pain; priority journal; recurrent laryngeal nerve palsy; seroma; skin flap; thyroid weight; thyroidectomy; transoral robotic surgery; middle aged; minimally invasive surgery; neck dissection; postoperative period; procedures; retrospective study; robot assisted surgery; thyroid tumor; thyroidectomy | English | 2020 | 2020-11-01 | 10.1089/lap.2020.0102 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Intraoperative allogeneic blood transfusion is associated with adverse oncological outcomes in patients with surgically treated non-metastatic clear cell renal cell carcinoma | Background The objective of this study was to provide more definitive information about the prognostic impact of perioperative blood transfusion (PBT) on patients with surgically treated renal cell carcinoma (RCC). Methods A database of 4019 patients with clear cell RCC, all of whom underwent radical or partial nephrectomy as primary therapy as part of a multi-institutional Korean collaboration between 1988 and 2015, was analyzed retrospectively. PBT was defined as transfusion of allogeneic red blood cells during surgery or postsurgical period. Receipt of a PBT, as well as the amount and time of blood transfusion (BT), was compared. Results Overall, 335 (8.3%) patients received a PBT: 84 received postoperative BT, 202 received intraoperative BT, and 49 received both intraoperative and postoperative BT. Patients receiving a PBT had a poor preoperative immuno-nutritional status, and aggressive tumor characteristics. Multivariate analyses identified PBT as an independent predictor of recurrence-free survival and cancer-specific survival. Prognostic impact of PBT was restricted to those with locally advanced stage (pT3-4), and who underwent radical nephrectomy. Among patients who received a PBT, intraoperative (but not postoperative) BT was a prognostic factor for survival. Among patients who received intraoperative BT, those receiving three or more transfusion units had a significantly worse survival. Conclusion Receipt of a PBT was an independent predictor of RFS and CSS in patients with surgically treated RCC, specifically locally advanced disease. Regarding the prognostic impact of timing or dose of PBT on survival, intraoperative BT and >= 3 pRBC units were associated with adverse oncological outcomes. | Kang, Ho Won; Seo, Sung Pil; Kim, Won Tae; Yun, Seok Joong; Lee, Sang-Cheol; Kim, Wun-Jae; Hwang, Eu Chang; Kang, Seok Ho; Hong, Sung-Hoo; Chung, Jinsoo; Kwon, Tae Gyun; Kim, Hyeon Hoe; Kwak, Cheol; Byun, Seok-Soo; Kim, Yong-June | Chungbuk Natl Univ, Dept Urol, Coll Med, 1st Chungdae Ro, Cheongju 28644, Chungbuk, South Korea; Chungbuk Natl Univ Hosp, Dept Urol, Cheongju, South Korea; Chonnam Natl Univ, Dept Urol, Hwasun Hosp, Hwasun Gun, South Korea; Korea Univ, Dept Urol, Sch Med, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Urol, Seoul, South Korea; Natl Canc Ctr, Dept Urol, Goyang, South Korea; Kyungpook Natl Univ, Dept Urol, Coll Med, Daegu, South Korea; Seoul Natl Univ, Dept Urol, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Urol, Bundang Hosp, 166 Gumi Ro, Seongnam 463707, Kyunggi Do, South Korea | ; Kim, Yong-June/E-5622-2012; Lee, Sang/E-4151-2012; Kim, Jae-hyung/J-8504-2012; Kim, Kyu/E-7814-2012; Kwak, Cheol/J-2731-2012; Hwang, Eu/K-3680-2019; Kim, Hyeon/J-5450-2012 | 35757703900; 56115644100; 57203514393; 16302421300; 57218216917; 8081691400; 8441681300; 7405684686; 37030299600; 16678454900; 15073765400; 56593347100; 7005639032; 7004818488; 26422204800 | ssbyun@snubh.org;urokyj@cbnu.ac.kr; | INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY | INT J CLIN ONCOL | 1341-9625 | 1437-7772 | 25 | 8 | SCIE | ONCOLOGY | 2020 | 3.402 | 66.7 | 0.18 | 2025-06-25 | 7 | 7 | Renal cell carcinoma; Nephrectomy; Transfusion; Prognosis; Survival | UROTHELIAL CARCINOMA; SURVIVAL; CANCER; PROGNOSIS; SURGERY; IMPACT; RECURRENCE | Nephrectomy; Prognosis; Renal cell carcinoma; Survival; Transfusion | Adult; Aged; Blood Transfusion; Carcinoma, Renal Cell; Female; Humans; Intraoperative Care; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Multivariate Analysis; Nephrectomy; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome; adult; advanced cancer; adverse outcome; allogeneic red blood cell transfusion; Article; cancer patient; cancer prognosis; cancer specific survival; controlled study; erythrocyte transfusion; female; human; immune status; major clinical study; male; nutritional status; partial nephrectomy; perioperative period; priority journal; radical nephrectomy; recurrence free survival; renal cell carcinoma; retrospective study; adverse event; aged; blood transfusion; clinical trial; Kaplan Meier method; kidney tumor; middle aged; mortality; multicenter study; multivariate analysis; nephrectomy; pathology; peroperative care; procedures; prognosis; renal cell carcinoma; survival rate; treatment outcome | English | 2020 | 2020-08 | 10.1007/s10147-020-01694-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Gamma-ray bursts with extended emission: classifications, energy correlations and radiation properties | Thanks to more and more gamma-ray bursts with measured redshift and extended emission detected by the recent space telescopes, it is urgent and possible to check whether those previous energy correlations still satisfy the particular sample involving only the bursts accompanied by tail radiations. Using 20 long and 22 short bursts with extended emission, we find that the popular gamma-ray energy correlations of the intrinsic peak energy versus the isotropic energy (Amati relation) and the intrinsic peak energy versus the peak luminosity (Yonetoku relation) do exist in both short and long bursts. However, it is much better if these gamma-ray bursts with extended emissions are reclassified into two subgroups of E-I and E-II that make the above energy correlations more tight. As proposed by Zhang et al., the energy correlations can be utilized to distinguish these kinds of gamma-ray bursts in the plane of bolometric fluence versus peak energy as well. Interestingly, the peculiar short GRB 170817A belongs to the E-I group in the fluence versus peak energy plane, but it is an outlier of both the Amati and Yonetoku relations even though the off-axis effect has been corrected. Furthermore, we compare the radiation features between the extended emissions and the prompt gamma-rays in order to search for their possible connections. Taking into account all these factors, we conclude that gamma-ray bursts with extended emission are still required to model with dichotomic groups, namely E-I and E-II classes, which hint that they might have different origins. | Zhang, Xiao-Lu; Zhang, Chuan-Tao; Li, Xu-Juan; Su, Fu-Fang; Dong, Xiao-Fei; Chang, Heon-Young; Zhang, Zhi-Bin | Qufu Normal Univ, Coll Phys & Engn, Qufu 273165, Shandong, Peoples R China; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, 1370 Sankyuk Dong, Daegu 702701, South Korea; Qufu Normal Univ, Shandong Prov Key Lab Laser Polarizat & Informat, Qufu 273165, Shandong, Peoples R China | zhang, zhibin/IQS-5892-2023 | 58449541200; 57218183372; 57221809567; 8881632300; 57216888420; 7407524806; 57192634952 | astrophy0817@163.com; | RESEARCH IN ASTRONOMY AND ASTROPHYSICS | RES ASTRON ASTROPHYS | 1674-4527 | 2397-6209 | 20 | 12 | SCIE | ASTRONOMY & ASTROPHYSICS | 2020 | 1.469 | 66.9 | 0.41 | 2025-06-25 | 13 | 13 | gamma-ray burst: general; method: statistics; radiation mechanisms: non-thermal | PEAK LUMINOSITY; SHORT GRBS; AFTERGLOW; ESTIMATOR; INJECTION; ACCRETION; SUPERNOVA; EVOLUTION; INDICATOR; SPECTRA | Gamma-ray burst: general; Method: statistics; Radiation mechanisms: non-thermal | English | 2020 | 2020-12 | 10.1088/1674-4527/20/12/201 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Synergetic effect of cross-linking and interfacial interaction in carbon fiber reinforced thermoplastic to enhance its tensile strength by electron-beam irradiation | A carbon fiber reinforced thermoplastic (CFRTP) was irradiated with a high energy electron-beam. As a result, the tensile strength of high-density polyethylene (HDPE)-based CFRTPs was significantly improved by gradually increasing the electron-beam dose. It was confirmed that the adhesion between CF and HDPE was improved and the surface properties of CF and HDPE were readily modified by electron-beam. It was verified from spectroscopic analysis that various oxygen-containing functional groups were formed on the surface of CF and HDPE by irradiation and we believe that strong attractive interactions took place among these functional groups at the interface of CFs and HDPE. Finally, it was conclusive that electron-beam irradiation provided two main effects on CFRTPs. One was cross-linking of thermoplastic resin for efficient load transfer from resin to CF and the other was formation of surface functional group and attractive interaction of these functional groups at the interface of fiber and matrix. These two effects showed synergetic contribution to enhance the mechanical properties of CFRTP. | Jung, Soonyoung; Park, Se Kye; Ghim, Han-do; Lee, Dong Yun; Yoo, Seung Hwa | Korea Inst Ind Technol, Daegyeong Reg Div, 59 Yangho Gil, Yeongcheon Si 38822, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Dept Adv Organ Mat Sci & Engn, Daegu, South Korea; Kyungpook Natl Univ, Dept Polymer Sci & Engn, Daegu, South Korea | 57210572051; 57210575824; 6602195799; 57211001605; 57190001859 | shyoo@kitech.re.kr; | CARBON LETTERS | CARBON LETT | 1976-4251 | 2233-4998 | 30 | 2 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2020 | 1.917 | 67.1 | 1.08 | 2025-06-25 | 21 | 22 | Electron-beam irradiation; Carbon fiber reinforced thermoplastic; Oxygen-containing functional group; Fiber-matrix interface; Interfacial adhesion; Attractive interaction | FIBER/EPOXY COMPOSITES; MECHANICAL-PROPERTIES; FUNCTIONAL-GROUPS; ADHESION; IMPROVEMENT; POLYETHYLENE; NANOTUBES; OXIDATION; SURFACES; ENERGY | Attractive interaction; Carbon fiber reinforced thermoplastic; Electron-beam irradiation; Fiber-matrix interface; Interfacial adhesion; Oxygen-containing functional group | Adhesion; Electron beams; Electrons; Fiber reinforced plastics; Fibers; High density polyethylenes; Irradiation; Oxygen; Resins; Spectroscopic analysis; Attractive interactions; Carbon fiber reinforced; Carbon fiber reinforced thermoplastic; Cross linking; Electron beam irradiation; Fiber reinforced thermoplastics; Fiber/matrix interface; High-density polyethylenes; Interfacial adhesions; Oxygen-containing functional groups; Tensile strength | English | 2020 | 2020-04 | 10.1007/s42823-019-00082-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Identification of Zoonotic Tick-Borne Pathogens from Korean Water Deer (Hydropotes inermis argyropus) | Korean water deer (Hydropotes inermis argyropus) are widespread in the Republic of Korea (ROK). Mostly, Korean water deer are essential hosts for maintaining ticks and tick-borne diseases (TBDs). Here, we investigated the prevalence of tick-borne pathogens (TBPs) among rescued Korean water deer.Anaplasma phagocytophilum(21.4%, 6/28),Anaplasma capra(14.3%, 4/28),Babesia capreoli(3.6%, 1/28), andCoxiella burnetii(3.6%, 1/28) were detected, butBorrelia burgdorferi,Ehrlichia,Rickettsia, andTheileriainfections were not found.A. phagocytophilumwas the most commonly detected pathogen, and co-infection withA.capraandB.capreoliwas also noted in one Korean water deer. To our knowledge, this is the first article ofB.capreoliinfection in Korean water deer in the ROK. The infecting isolate ofA. phagocytophilumwas genetically characterized by 16S ribosomal RNA (rRNA) gene and ankyrin-related protein (ankA) gene. Although the 16S rRNA gene alone may not be informative enough to delineate distinct host species,ankA-based phylogeny revealed a high identity of Korean water deer sequences with those of the causative agent of human granulocytic anaplasmosis.A. caprawas detected by using citrate synthase gene (gltA), heat-shock protein (groEL), and major surface protein 4 (msp4) genes. Phylogenetic tree based on these gene markers revealed that there were at least two distinct variants withinA. capracirculating in the ROK. One variant originated from different hosts including humans, ticks, goats, and sheep, whereas the other variant was reported recently in Korean water deer in the ROK. Consequently, these sequences were identified to belong to a zoonotic species. Sequencing analysis of the 18S rRNA gene revealed that our isolate belonged toB. capreoliand was distinct fromBabesia divergensandBabesia venatorum. Moreover, our isolate showed 92.2% homology withB. capreolisequences, indicating that these differences may be attributed to the different tick species that transmitB. capreolior to different host species. Genotyping and phylogenetic analysis ofC. burnetiibased on 16S rRNA and IS1111 genes revealed that our isolate was grouped with several strains ofC. burnetiiand was genetically distant fromCoxiella-like bacteria isolates. The present results highlight that Korean water deer act as potential reservoir hosts for zoonotic TBPs, and thus play an important role in the transmission of TBDs in humans, animals, and livestock. | Shin, Seung-Uk; Park, Yu-Jin; Ryu, Ji-Hyoung; Jang, Dong-Hun; Hwang, Sunwoo; Cho, Hyung-Chul; Park, Jinho; Han, Jae-Ik; Choi, Kyoung-Seong | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Coll Ecol & Environm Sci, Sangju 37224, South Korea; Kyungpook Natl Univ, Coll Ecol & Environm Sci, Dept Horse Compan & Wild Anim, Sangju, South Korea; Jeonbuk Natl Univ, Coll Vet Med, Dept Vet Internal Med, Iksan, South Korea; Jeonbuk Natl Univ, Coll Vet Med, Lab Wild Med, Iksan, South Korea | kschoi3@knu.ac.kr; | VECTOR-BORNE AND ZOONOTIC DISEASES | VECTOR-BORNE ZOONOT | 1530-3667 | 1557-7759 | 20 | 10 | SCIE | INFECTIOUS DISEASES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 2.133 | 67.2 | 20 | Anaplasma phagocytophilum; Anaplasma capra; Babesia capreoli; Coxiella burnetii; Korean water deer | COXIELLA-BURNETII INFECTION; ANAPLASMA-PHAGOCYTOPHILUM; Q-FEVER; BABESIA SPP.; RUMINANTS; COINFECTION; PREVALENCE; BOVIS; GENE; PCR | English | 2020 | 2020-10-01 | 10.1089/vbz.2019.2609 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Molecular and Serological Investigation of Severe Fever with Thrombocytopenia Syndrome Virus in Cats | Background:Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonosis in China, the Republic of Korea (ROK), and Japan. The presence of the SFTS virus (SFTSV) in companion, livestock, and wild animals has been reported. Recently, human SFTS-like clinical symptoms in cats and cheetahs have been reported in Japan. Therefore, the prevalence of the SFTSV gene or antibody in cats is important for public health as well as veterinary medicine. Materials and Methods:Sera were collected from 201 feral and house cats in the ROK in 2017. Samples were analyzed for the presence of the SFTSV gene after RT-nested PCR amplification and for anti-SFTSV antibodies after enzyme linked immunosorbent assay. Results:Eight (4.0%) and nine (4.5%) of 201 cat sera were found to be positive for the SFTSV gene and anti-SFTSV nucleocapsid protein antibodies, respectively. Specifically, 5.9% feral and 2.0% house cats were positive for the SFTSV gene, and 6.9% feral and 2.0% house cats were positive for anti-SFTSV antibodies. All sequences of the SFTSV S segment obtained were included in Japanese/Korean SFTSV clades, as opposed to the Chinese clade. Conclusions:This study constitutes the first serological study of SFTSV in house and feral cats in the ROK. Evidence of SFTSV in companion animals indicates that SFTSV can circulate in homes and that more intensive precautions and education measures are needed for companion animal guardians and veterinarians. | Kang, Jun-Gu; Cho, Yoon-Kyung; Han, Sun-Woo; Jeon, Kyeongseok; Choi, Hooncheol; Kim, Jong-Ho; Cho, Nam-Hyuk; Choi, Kyoung-Seong; Chae, Joon-Seok | Seoul Natl Univ, Coll Med, Dept Microbiol & Immunol, Seoul, South Korea; Seoul Natl Univ, Med Res Ctr, Inst Endem Dis, Seoul, South Korea; Seoul Natl Univ, Res Inst Vet Sci, BK21 Plus Program Creat Vet Sci Res, Lab Vet Internal Med, Seoul 08826, South Korea; Seoul Natl Univ, Coll Vet Med, Seoul 08826, South Korea; 24 Hours Smart Anim Med Ctr, Seoul, South Korea; Kyungpook Natl Univ, Coll Ecol & Environm Sci, Dept Anim Sci & Biotechnol, Sangju, South Korea | Choi, Eun-Young/JXO-0422-2024 | 40561359000; 59795833400; 57216636732; 57211714813; 57211711708; 57220168973; 34973855600; 7403949556; 7102478039 | jschae@snu.ac.kr; | VECTOR-BORNE AND ZOONOTIC DISEASES | VECTOR-BORNE ZOONOT | 1530-3667 | 1557-7759 | 20 | 12 | SCIE | INFECTIOUS DISEASES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 2.133 | 67.2 | 0.54 | 2025-06-25 | 14 | 13 | severe fever with thrombocytopenia syndrome virus; SFTS; tick-borne pathogen; cat; Korea | SOUTH-KOREA; ANIMALS; DOGS | cat; Korea; severe fever with thrombocytopenia syndrome virus; SFTS; tick-borne pathogen | Animals; Antibodies, Viral; Cats; Female; Genes, Viral; Male; Ownership; Phlebovirus; Republic of Korea; Seroepidemiologic Studies; Serologic Tests; nucleocapsid protein; viral protein; virus antibody; virus DNA; virus RNA; virus antibody; amplicon; antibody titer; Article; bacterial strain; blood sampling; cat; Chinese; cladistics; controlled study; DNA extraction; enzyme linked immunosorbent assay; female; feral cat; indirect ELISA; Japan; Korea; male; molecular diagnosis; nested polymerase chain reaction; nonhuman; nucleotide sequence; phylogenetic tree; phylogeny; prevalence; priority journal; real time polymerase chain reaction; serology; seroprevalence; severe fever with thrombocytopenia syndrome; virus gene; animal; blood; genetics; immunology; organization and management; Phlebovirus; seroepidemiology; serology; South Korea; virology | English | 2020 | 2020-12-01 | 10.1089/vbz.2020.2649 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Time series analysis of delta neutrophil index as the predictor of sepsis in patients with acute poisoning | Delta neutrophil index (DNI), which reflects the fraction of immature granulocytes, is used to detect infection and sepsis from noninfectious conditions, but few studies have evaluated in the early stage of acute poisoning. This retrospective observational study was performed on acute poisoning patients who visited to the emergency department (ED) and were consecutively admitted in intensive care units over 18-month period. The serial DNI, conventional inflammatory biomarkers, and culture results were obtained in the ED and after admission. The outcomes were the identification of sepsis, bacteremia, and 30-day mortality. Of 166 patients (mean age, 56.0 years) in this cohort, 59 (35.5%) had sepsis and 29 (17.5%) had bacteremia. Initial and peak DNI fractions 24 h after ED admission were strong independent predictors of sepsis development. Analysis of the area under the curve according to multiple receiver operating characteristics showed that DNI had a higher capability to predict sepsis than other parameters (0.815 for DNI, 0.700 for procalcitonin, 0.681 for C-reactive protein, and 0.741 for white blood cell). Using multivariable logistic regression analysis, it was found that DNI was an independent predictor of sepsis (95% confidence interval (CI) of odds: 1.03-1.18) and bacteremia (95% CI: 1.01-1.14). Therefore, initial and serial measurement of DNI may serve as useful risk predictor for development of sepsis or bacteremia in acute poisoning. | Park, S. J.; Park, J.; Lee, M. J.; Seo, J. S.; Ahn, J. Y.; Cho, J. W. | Kyungpook Natl Univ, Dept Emergency Med, Sch Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Dongguk Univ, Dept Emergency Med, Ilsan Hosp, Coll Med, Seoul, South Korea | Ahn, Jae Yun/N-2652-2017 | 57221239353; 54389875200; 55507282600; 55614793100; 56937505400; 7403536065 | emmam@knu.ac.kr; | HUMAN & EXPERIMENTAL TOXICOLOGY | HUM EXP TOXICOL | 0960-3271 | 1477-0903 | 39 | 1 | SCIE | TOXICOLOGY | 2020 | 2.903 | 67.2 | 0.51 | 2025-06-25 | 10 | 7 | Sepsis; delta neutrophil index; procalcitonin; biochemical markers; poisoning | INFLAMMATORY RESPONSE SYNDROME; CRITICALLY-ILL PATIENTS; CARE INFECTION SCORE; INTENSIVE-CARE; PROGNOSTIC MARKER; PROCALCITONIN; BACTERIAL; THERAPY; DISEASE | biochemical markers; delta neutrophil index; poisoning; procalcitonin; Sepsis | Biomarkers; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Inflammation; Male; Middle Aged; Neutrophils; Retrospective Studies; Sepsis; C reactive protein; procalcitonin; biological marker; acute poisoning; adult; aged; area under the curve; Article; bacteremia; controlled study; delta neutrophil index; disease association; emergency ward; female; granulocyte; hospital admission; human; intensive care unit; intoxication; leukocyte; major clinical study; male; mortality; neutrophil; observational study; prediction; priority journal; receiver operating characteristic; retrospective study; risk factor; sepsis; time series analysis; adverse drug reaction; inflammation; middle aged; neutrophil; physiology; sepsis | English | 2020 | 2020-01 | 10.1177/0960327119878244 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | On a conjecture posed by Benhissi and Koja | Let = (R-n)(n >= 0) be an ascending chain of commutative rings with identity and (resp., ) the generalized composite Hurwitz series ring (resp., generalized composite Hurwitz polynomial ring). In this paper, we completely characterize when the rings and are PS-rings. More precisely, we show that and are always PS-rings. This is an affirmative answer to the question raised by Benhissi and Koja. Communicated by Silvana Bazzoni | Kim, Dong Kyu; Lim, Jung Wook | Kyungpook Natl Univ, Coll Nat Sci, Dept Math, Daegu 41566, South Korea | 57211492493; 35766755400 | jwlim@knu.ac.kr; | COMMUNICATIONS IN ALGEBRA | COMMUN ALGEBRA | 0092-7872 | 1532-4125 | 48 | 6 | SCIE | MATHEMATICS | 2020 | 0.762 | 67.4 | 0 | 2025-06-25 | 1 | 1 | Annihilator; generalized composite Hurwitz series ring; generalized composite Hurwitz polynomial ring; idempotent element; PS-ring | RINGS | Annihilator; generalized composite Hurwitz polynomial ring; generalized composite Hurwitz series ring; idempotent element; PS-ring | English | 2020 | 2020-06-02 | 10.1080/00927872.2020.1721733 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Opuntia humifusa aqueous extract alleviates ethanol-induced gastric ulcer in a mouse model | Objective: To investigate the effect of Opuntia humifusa aqueous extract on gastric ulcers. Methods: An ethanol-induced model was used to examine the protective effect of Opuntia humifusa against gastric ulcers. The gastric ulcer index was evaluated via clinical observation and image analysis. Various inflammatory indicators were determined by RT-PCR and Western blotting assays. Results: The gastric ulcer index was reduced to 8% in the group treated with Opuntia humifusa aqueous extract compared with that in the control group. RT-PCR analysis revealed that MUC5AC expression was reduced to 39% in the control group compared with the non-treated group, whereas the omeprazole and Opuntia humifusa aqueous extract-treated groups increased the expression to 95% and 79%, respectively. Moreover, the expressions of various cytokines including TNF-alpha, IL-1 beta, and IL-6 were increased in the control group, while decreasing in Opuntia humifusa aqueous extract-treated group. Opuntia humifusa aqueous extract also suppressed the expressions of iNOS, COX-2, and its transcription factor NF-kappa B and increased mucus content considerably as compared to the control group. Conclusions: These results suggest that Opuntia humifusa aqueous extract is suitable as an alternative remedy for gastric ulcer treatment. | Yoo, Chi-Yeol; Son, Hyeong-U; Fanar, Alshammari; Choi, Hee-Jung; Alam, Md; Lee, Sang-Han | Kyungpook Natl Univ, Dept Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Food & Bioind Res Inst, Daegu 41566, South Korea | Lee, Seung Eun/ABG-1607-2021; kim, jm/O-5935-2014 | 57201151911; 53881847500; 57218551129; 58742906900; 56706777100; 57221453703 | sang@knu.ac.kr; | ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE | ASIAN PAC J TROP BIO | 2221-1691 | 2588-9222 | 10 | 9 | SCIE | TROPICAL MEDICINE | 2020 | 1.545 | 67.4 | 0.24 | 2025-06-25 | 3 | 6 | DAMAGE; INFLAMMATION; EXPRESSION | Gastric lesions; Gastric ulcer; Image analysis; Mucin; Opuntia humifusa | antiulcer agent; chlorogenic acid; cyclooxygenase 2; gallic acid; immunoglobulin enhancer binding protein; inducible nitric oxide synthase; interleukin 1; interleukin 13; interleukin 4; interleukin 6; mucin 5AC; omeprazole; Opuntia extract; Opuntia humifusa extract; rutoside; tumor necrosis factor; unclassified drug; animal experiment; animal model; animal tissue; Article; controlled study; ethanol-induced gastric ulcer; gene expression; high performance liquid chromatography; immunohistochemistry; male; mouse; nonhuman; Opuntia; Opuntia humifusa; priority journal; protein expression; real time polymerase chain reaction; RNA analysis; stomach tissue | English | 2020 | 2020-09 | 10.4103/2221-1691.290131 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Some change of rings results on (n, m)-SG modules and (n, m)-SG rings | Let nP1 and kP0 be fixed integers and R be a ring. We show that R is (n, k)-SG with G-gldimoR= k if and only if Rx1, x2, :::, xm is on, k = m=-SG with G-gldimoRx1, x2, :::, xm= k = m: We also give an example of a 2-SGDedekind domain which is not an SG-Dedekind domain. | Hu, Kui; Lim, Jung Wook; Zhou, De Chuan | Southwest Univ Sci & Technol, Coll Sci, Mianyang 621010, Sichuan, Peoples R China; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea | 55557444100; 35766755400; 56739669900 | hukui200418@163.com; | COMMUNICATIONS IN ALGEBRA | COMMUN ALGEBRA | 0092-7872 | 1532-4125 | 48 | 9 | SCIE | MATHEMATICS | 2020 | 0.762 | 67.4 | 0.57 | 2025-06-25 | 3 | 3 | n-SG-projective module; n-SG-global dimensions; n-SG-injective modules | n-SG-global dimensions; n-SG-injective modules; n-SG-projective module | English | 2020 | 2020-09-01 | 10.1080/00927872.2020.1754843 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Review | Microbial extracellular RNAs and their roles in human diseases | Extracellular RNAs (exRNAs) are released by extracellular vesicles, small membranous nanoparticles secreted by all cell types. When transported into cells, exRNAs can modulate gene expression or cellular responses in the target cells since many small RNAs have regulatory functions. Indeed, it is widely acknowledged that endogenous exRNAs in the human body are related to various diseases. However, microbial exRNAs have been less studied, and their connection to host diseases has just begun to be explored. In this review, I will discuss analytical methods for exRNAs and the potential use of exRNAs as disease biomarkers. I also consider current progress in understanding the regulation of host mechanisms by microbial exRNAs as inter-kingdom communication, efforts to utilize extracellular vesicles as therapeutic vehicles loaded with engineered RNA cargos, and a putative connection between microbial exRNA-based regulation of host responses and human diseases such as Alzheimer's. This overview aims to present novel insights into pathogenesis with regard to the function of microbial exRNAs as "disease-relevant travelers." Impact statement The number of commensal bacteria in the body surpasses the number of actual human cells. Thus, various interactions between microbes and human cells constitute an inevitable phenomenon. Recent evidence has led to bacterial extracellular RNAs (exRNAs) being proposed as good candidates for microbe-host inter-kingdom communication tools as they can modulate the expression of host genes. However, research findings on the relevance of interactions between extracellular RNA and human diseases are still in their infancy. Nevertheless, substantial data suggest that microbial exRNAs are implicated in various human diseases both at local and distant sites. By exploring various scenarios for the involvement of microbial exRNAs in human diseases, we may better understand the role of exRNAs as "communication signals" for diseases and thereby develop novel therapeutic strategies by using them and their carrier extracellular vesicles. | Lee, Heon-Jin | Kyungpook Natl Univ, Dept Microbiol & Immunol, Sch Dent, Daegu 4940, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41940, South Korea | 36462383000 | heonlee@knu.ac.kr; | EXPERIMENTAL BIOLOGY AND MEDICINE | EXP BIOL MED | 1535-3702 | 1535-3699 | 245 | 10 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL | 2020 | 2.691 | 67.5 | 0.2 | 2025-06-25 | 9 | 9 | Extracellular vesicle; exosome; extracellular RNA; microRNA; small RNA; systemic disease; inter-kingdom communication | OUTER-MEMBRANE VESICLES; MICRORNA-SIZE; BACTERIA; BIOGENESIS; SECRETION | exosome; extracellular RNA; Extracellular vesicle; inter-kingdom communication; microRNA; small RNA; systemic disease | Extracellular Vesicles; Humans; Microbiota; RNA, Bacterial; biological marker; interleukin 8; microRNA; small interfering RNA; bacterial RNA; Aggregatibacter actinomycetemcomitans; antimicrobial activity; bioinformatics; Borrelia burgdorferi; cancer therapy; Candida albicans; density gradient centrifugation; endocytosis; Escherichia coli; exosome; flow cytometry; gene control; gene expression; human; immunoprecipitation; microbial activity; Mycobacterium marinum; Mycobacterium tuberculosis; nonhuman; phagocytosis; Porphyromonas gingivalis; Pseudomonas aeruginosa; Review; RNA sequence; signal transduction; tumor volume; ultracentrifugation; exosome; microflora | English | 2020 | 2020-05 | 10.1177/1535370220923585 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Novel 2019 coronavirus: Genome structure, clinical trials, and outstanding questions | Novel 2019 coronavirus has created havoc across the globe since its emergence in December 2019 in Wuhan, China, and fast spreading potential. While we were able to identify the causative agent within a few days of the disease outbreak, several questions still remain unanswered. In this review, we discuss the extent of virus spread, current statistics, SARS-CoV-2 genome organization, comparison between the novel coronavirus and causative agents involved in previous outbreaks, ongoing clinical trials and myths associated with the virus. Lastly, we provide insights into the future perspectives which could prove useful for the scientific community as they work on finding the cure against the disease. Impact statement Early availability of the sequence, the genetic material of SARS-CoV-2 (the virus that causes COVID-19), has prompted efforts towards identifying a safe and effective vaccine in the current public health emergency. To that end, understanding the pathophysiology of disease is crucial for scientists around the world. Since conventional vaccine development and manufacturing may take several years, it is important to think about alternative strategies that we could use to mitigate imminent catastrophe. We hope that this article will open up new avenues and provide insights that could potentially save hundreds of lives affected by COVID-19. | Jogalekar, Manasi P.; Veerabathini, Anurag; Gangadaran, Prakash | Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA; Maxim Integrated Prod Inc, Chandler, AZ 85225 USA; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Nucl Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu 41944, South Korea | Veerabathini, Anurag/T-4152-2019; Gangadaran, Prakash/AAV-3102-2021; Jogalekar, Manasi/AAG-6925-2020 | 57194462336; 57216493774; 54393130400 | prakash.gangadaran@hotmail.com;prakashg@knu.ac.kr; | EXPERIMENTAL BIOLOGY AND MEDICINE | EXP BIOL MED | 1535-3702 | 1535-3699 | 245 | 11 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL | 2020 | 2.691 | 67.5 | 0.95 | 2025-06-25 | 22 | 26 | SARS-CoV-2; COVID-19; coronavirus; Wuhan; 2019-nCoV; MERS-CoV; SARS-CoV; China | 2019-nCoV; China; coronavirus; COVID-19; MERS-CoV; SARS-CoV; SARS-CoV-2; Wuhan | Adenosine Monophosphate; Alanine; Antiviral Agents; Betacoronavirus; China; Communicable Disease Control; Coronavirus Infections; Genome, Viral; Humans; Middle East Respiratory Syndrome Coronavirus; Pandemics; Pneumonia, Viral; SARS Virus; Serine Proteinase Inhibitors; adenosine phosphate; alanine; antivirus agent; remdesivir; serine proteinase inhibitor; anorexia; Article; artificial intelligence; coronavirus disease 2019; coughing; disease surveillance; fatigue; gene structure; health care policy; heart arrhythmia; human; immune response; lymphocytopenia; machine learning; Middle East respiratory syndrome coronavirus; nonhuman; public health; Severe acute respiratory syndrome coronavirus 2; vaccination; virus detection; virus replication; virus shedding; Betacoronavirus; China; communicable disease control; Coronavirus infection; drug effect; genetics; pandemic; procedures; SARS coronavirus; virus genome; virus pneumonia | English | 2020 | 2020-06 | 10.1177/1535370220920540 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Production of 7,10,12-trihydroxy-8(E)-octadecenoic acid from ricinoleic acid by Pseudomonas aeruginosa KNU-2B | Microbial production of hydroxy fatty acids (HFAs) was widely studied because of important biological properties of HFAs. Among microorganisms producing HFAs, Pseudomonas aeruginosa PR3 was well known to produce various HFAs from different unsaturated fatty acids. Recently, a new variant species of P. aeruginosa PR3 was isolated and characterized, showing improved efficiency for producing 7,10-dihydroxy-8(E)-octadecenoic acid from oleic acid. In this study, we report the production of 7,10,12-trihydroxy-8(E)-octadecenoic acid (TOD) from ricinoleic acid by the newly isolated P. aeruginosa KNU-2B. TOD was efficiently produced from ricinoleic acid by KNU-2B with the maximum conversion yield of 56.7% under the optimum reaction conditions of pH 8.0 and 48-h incubation at 27 degrees C, 150 rpm. Under optimized reaction conditions, maximum TOD production reached 340.3 mg/100 mL of the culture. However, requirement of nutritional factors by KNU-2B for production of TOD were considerably different from those by PR3 strain. | Lee, Yeon-Jung; Moon, Ji-Sun; Kim, In-Hwan; Kim, Hak-Ryul | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Korea Univ, Grad Sch, Dept Publ Hlth Sci, Seoul, South Korea; Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu, South Korea | Lee, Eun-Hye/KDN-5679-2024 | 57213606684; 57216253626; 47161438300; 57191717289 | hakrkim@knu.ac.kr; | BIOTECHNOLOGY LETTERS | BIOTECHNOL LETT | 0141-5492 | 1573-6776 | 42 | 8 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2020 | 2.461 | 67.6 | 0 | 2025-06-25 | 2 | 2 | Pseudomonas aeruginosa KNU-2B; Bioconversion; Trihydroxy fatty acid; Optimization; Ricinoleic acid | (9,12,13)-TRIHYDROXY-11E (10E)-OCTADECENOIC ACID; HYDROXY FATTY-ACIDS; LINOLEIC-ACID; 7,10-DIHYDROXY-8(E)-OCTADECENOIC ACID; OLEIC-ACID; ANTIBACTERIAL ACTIVITY; CONVERSION; COMPOUND; PLANT; BIOCONVERSION | Bioconversion; Optimization; Pseudomonas aeruginosa KNU-2B; Ricinoleic acid; Trihydroxy fatty acid | Hydroxy Acids; Oleic Acids; Pseudomonas aeruginosa; Ricinoleic Acids; Bacteria; Bioconversion; Monounsaturated fatty acids; Optimization; 7,10,12-trihydroxy-8-octadecenoic acid; hydroxyacid; oleic acid; ricinoleic acid; Biological properties; Hydroxy fatty acids; Microbial production; Nutritional factors; Optimized reaction conditions; Optimum reaction conditions; Pseudomonas aeruginosa; Ricinoleic acid; chemistry; metabolism; Pseudomonas aeruginosa; Oleic acid | English | 2020 | 2020-08 | 10.1007/s10529-020-02883-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Strong alkaline condition is preferable for producing 7,10-dihydroxy-8(E)-hexadecenoic acid from palmitoleic acid by Pseudomonas aeruginosa KNU-2B | Microbial bioconversion of a given substrate is considered an efficient and eco-friendly tool for value-added industrial compound generation from natural products. Among natural products, unsaturated fatty acids have been used as substrates to produce various functional hydroxy fatty acids. In this study, we report the production of 7,10-dihydroxy-8(E)-hexadecenoic acid (DHD) from palmitoleic acid by a new strain, Pseudomonas aeruginosa KNU-2B. KNU-2B efficiently produced DHD from palmitoleic acid and required a strong alkaline condition for maximum DHD production. The maximum DHD amount produced under pH 10.0 and 48-h incubation at 27 degrees C and 150 rpm was 219.5 mg/100 mL culture. Other important nutritional factors were also investigated to obtain optimum DHD production. | Moon, Ji-Sun; Lee, Yeon-Jung; Kim, In-Hwan; Kim, Hak-Ryul | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Korea Univ, Grad Sch, Dept Publ Hlth Sci, Seoul, South Korea; Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu, South Korea | Lee, Eun-Hye/KDN-5679-2024 | 57216253626; 57213606684; 47161438300; 57191717289 | hakrkim@knu.ac.kr; | BIOTECHNOLOGY LETTERS | BIOTECHNOL LETT | 0141-5492 | 1573-6776 | 42 | 9 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2020 | 2.461 | 67.6 | 0 | 2025-06-25 | 1 | 1 | Palmitoleic acid; Dihydroxy fatty acid; Alkaline condition; Bioconversion; Pseudomonas aeruginosa KNU-2B | HYDROXY FATTY-ACIDS; LINOLEIC-ACID; OLEIC-ACID; 7,10-DIHYDROXY-8(E)-OCTADECENOIC ACID; RICINOLEIC ACID; COMPOUND; INTERMEDIATE; CONVERSION; BIOCONVERSION; PLANT | Alkaline condition; Bioconversion; Dihydroxy fatty acid; Palmitoleic acid; Pseudomonas aeruginosa KNU-2B | Bioreactors; Culture Media; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Hydrogen-Ion Concentration; Pseudomonas aeruginosa; Alkalinity; Bacteria; Substrates; 7,10-dihydroxy-8-hexadecenoic acid; monounsaturated fatty acid; palmitoleic acid; unsaturated fatty acid; Alkaline conditions; Eco-friendly; Hydroxy fatty acids; Industrial compounds; Natural products; Nutritional factors; Palmitoleic acid; Pseudomonas aeruginosa; bioreactor; chemistry; culture medium; metabolism; pH; Pseudomonas aeruginosa; Unsaturated fatty acids | English | 2020 | 2020-09 | 10.1007/s10529-020-02899-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | CRISPR/Cas-mediated Fubp1 silencing disrupts circadian oscillation of Per1 protein via downregulating Syncrip expression | Most living organisms have physiological and behavioral circadian rhythms controlled by molecular clocks. In mammals, several core clock genes show self-perpetuating oscillation profiles of their messenger RNAs (mRNAs) and proteins through an auto-regulatory transcription-translation feedback loop (TTFL). As a critical component in the molecular clock system, Period 1 (Per1) contributes to the maintenance of circadian rhythm duration predominantly in peripheral clocks. Alterations in Per1 expression and oscillating patterns lead to the development of cancers as well as circadian rhythm abnormalities. In this study, we demonstrate that the phasic profile of Per1 protein was clearly disrupted in CRISPR/Cas-mediated Fubp1-deficient cells. Although Fubp1 does not show rhythmic expression, Fubp1 upregulates the mRNA and protein level of Syncrip, the main post-transcriptional regulator of Per1 protein oscillation. In addition to the diverse physiological functions of Fubp1, including cell-cycle regulation and cellular metabolic control, our results suggest new roles for Fubp1 in the molecular clock system. | Kim, Tae-Jun; Sung, Jae Hun; Shin, Jae-Cheon; Kim, Do-Yeon | Kyungpook Natl Univ, Sch Dent, Dept Pharmacol, Daegu 41940, South Korea; Pohang Ctr Evaluat Biomat, Pohang Technopk, Pohang 37668, Gyeongbuk, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41940, South Korea | ; Kim, Do-Yeon/AET-3021-2022; Kim, Yong-Tae/HQZ-0240-2023 | 57200911346; 57211444360; 56446079300; 57203012542 | jcshin@ptp.or.kr;dykim82@knu.ac.kr; | CELL BIOLOGY INTERNATIONAL | CELL BIOL INT | 1065-6995 | 1095-8355 | 44 | 2 | SCIE | CELL BIOLOGY | 2020 | 3.612 | 68.0 | 0.12 | 2025-06-25 | 5 | 3 | circadian rhythm; CRISPR; Cas; Fubp1; oscillation; Per1; Syncrip | RNA-BINDING PROTEIN; HNRNP-Q; MESSENGER-RNA; GENE-EXPRESSION; TRANSLATION; CLOCKS | circadian rhythm; CRISPR/Cas; Fubp1; oscillation; Per1; Syncrip | Animals; Circadian Rhythm; CRISPR-Cas Systems; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation; Gene Silencing; Heterogeneous-Nuclear Ribonucleoproteins; Mice; NIH 3T3 Cells; Period Circadian Proteins; RNA, Messenger; RNA-Binding Proteins; cell protein; Fubp1 protein; messenger RNA; PER1 protein; Syncrip protein; unclassified drug; circadian rhythm signaling protein; DNA binding protein; fubp1 protein, mouse; heterogeneous nuclear ribonucleoprotein; messenger RNA; Per1 protein, mouse; RNA binding protein; Syncrip protein, mouse; Article; cell cycle regulation; cell metabolism; circadian rhythm; controlled study; CRISPR Cas system; down regulation; metabolic regulation; molecular clock; protein expression; protein function; protein protein interaction; transcription regulation; upregulation; animal; circadian rhythm; gene expression regulation; gene silencing; genetics; metabolism; mouse; NIH 3T3 cell line | English | 2020 | 2020-02 | 10.1002/cbin.11242 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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