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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Inferior-Medial Approach to Laparoscopic Splenic Vessel-Preserving Distal Pancreatectomy | Background and Objectives: Complete preservation of the splenic vessels is ideal during laparoscopic spleen- preserving distal pancreatectomy (LSPDP). However, this remains challenging and time-consuming because the vessels are often deeply embedded in the pancreatic parenchyma. Herein, we introduce our inferior-medial approach to laparoscopic splenic vessel-preserving distal pancreatectomy (lap-SVPDP) and evaluate its safety and feasibility. Methods: Forty-three patients underwent LSPDP performed by a single surgeon at our institution: 26 (60.5%) lap-SVPDPs with an inferior-medial approach and 17 with the laparoscopic Warshaw technique (lap-WT). We compared the outcomes of the 2 groups. No patient undergoing lap-SVPDP required conversion to laparotomy or lap-WT. Results: Most preoperative characteristics and postoperative outcomes did not differ between the 2 groups; neither the operation time nor the intraoperative blood loss differed despite the greater technical complexity of lapSVPDP. The mean tumor size was greater in the lap-WT than the lap-SVPDP group (P 5 .001). The splenic vein patency rate of the lap-SVPDP group was not inferior to that of the open SVPDP group treated by the same surgeon. Conclusion: Inferior-medial approach lap-SVPDP could be a safe and feasible technique for lap-SVPDP; neither blood loss nor operation time is increased. | Park, Kee Tae; Kim, Joo Dong | Daegu Catholic Univ, Sch Med, Dept Surg, 33 Duryugongwon Ro,17 Gil, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Surg, Daegu, South Korea | 59941547000; 59767378800 | milledr@cu.ac.kr; | JSLS-JOURNAL OF THE SOCIETY OF LAPAROENDOSCOPIC SURGEONS | JSLS-J SOC LAPAROEND | 1086-8089 | 28 | 3 | SCIE | SURGERY | 2024 | 1.8 | 42.8 | N/A | 0 | 0 | laparoscopic splenic vessel distal pancrea tectomy; spleen-preserving | SPLEEN; PATENCY; PRESERVATION; METAANALYSIS; STRATEGY | laparoscopic splenic vessel distal pancrea-tectomy; spleen-preserving | English | 2024 | 2024 (JUL-SEP) | 10.4293/jsls.2024.00028 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Analysis of Retrofit SCR System for Small-Sized Ship Diesel Engines Using Numerical Methods | Tier III is being implemented to regulate the nitrogen oxides (NOx) emitted from ships, and selective catalytic reduction (SCR) systems are installed in ships to comply with this regulation. However, it is difficult to apply an SCR system to small or remodeled ships, because the engine room has limited space. Moreover, an SCR system should be installed in the consideration of the back-pressure of the engine exhaust gas, and the pressure should be less than the allowable back-pressure (less than 150 mmH2O) downstream of the turbocharger. The purpose of this study was to identify the design parameters to install a retrofitted SCR system in the limited space inside the engine room. A performance test was performed to develop the retrofitted SCR system applicable to small and size ships. A CFD analysis was performed by varying the exhaust gas velocity (6-12 m/s) and the porosity of honeycomb (60-90%) after a verification of CFD analysis and experiment results, obtained from an actual SCR system in a small-size ship. It was confirmed that when the exhaust gas velocity decreased, the back-pressure downstream of the turbocharger was reduced. In addition, the pressure variation was minimal when the catalyst porosity was 70% or more at the constant 8 m/s gas velocity. The results of the current study can guide the design of the retrofitted SCR system in small-size ship that has limited engine room space. | Hwang, Sung-Chul; Nam, Hyungseok | GET SCR Co Ltd, R&D Ctr, Miryang 50404, South Korea; Kyungpook Natl Univ, Sch Mech Engn, Daegu 41950, South Korea | 57191483720; 57190418228 | namhs219@knu.ac.kr; | KOREAN JOURNAL OF CHEMICAL ENGINEERING | KOREAN J CHEM ENG | 0256-1115 | 1975-7220 | 41 | 8 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;ENGINEERING, CHEMICAL | 2024 | 3.2 | 42.9 | 0 | 2025-05-07 | 0 | 0 | Retrofitted SCR system; Diesel engine; Numerical analysis; Back-pressure; Tier III | PERFORMANCE; EMISSION; AMMONIA; OIL | Back-pressure; Diesel engine; Numerical analysis; Retrofitted SCR system; Tier III | Computational fluid dynamics; Gases; Nitrogen oxides; Numerical methods; Porosity; Selective catalytic reduction; Ships; Turbomachinery; Back pressures; CFD analysis; Down-stream; Engine exhaust gas; Engine rooms; Exhaust gas velocity; Limited space; Retrofitted selective catalytic reduction system; Selective catalytic reduction systems; Tier III; Diesel engines | English | 2024 | 2024-08 | 10.1007/s11814-024-00143-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Effects of loading frequency and specimen size on the liquefaction resistance of clean sand | This study investigates the effects of loading frequency ( f ) and specimen size on the liquefaction resistance of clean sand. A series of cyclic direct simple shear tests were conducted on Jumunjin sand with varying consolidated relative densities (40% and 80%), f values (0.05, 0.10, and 0.20 Hz), and diameter to height ( D/H ) ratios (3.63, 3.18, 2.82, and 2.54). The results demonstrated the significant influence of f and D/H ratio on the number of cycles to liquefaction ( N cyc - liq ) and the cyclic resistance ratio ( CRR 15 ). It was observed that increasing f linearly increased N cyc - liq . Increasing the specimen height also led to higher N cyc - liq values irrespective of the f or relative density. Moreover, a positive correlation between CRR 15 and f indicated that higher f yielded higher CRR 15 . This relationship was more pronounced in dense sand than in loose sand. Specimen height also significantly affected CRR 15 , with increasing the specimen height resulting in higher CRR 15 values. Furthermore, the effect of f on CRR 15 was less significant compared to the influence of specimen height. The effect of f on the normalized cyclic resistance ratio ( NCRR ) was relatively negligible for loose sand but more substantial for dense sand depending on the D/H ratio. Data analysis revealed that the NCRR generally decreases as the D/H ratio increases. An interpolation formula was provided to calculate the NCRR based on the D/H ratio regardless of the f and relative density. | Park, Sung-Sik; Lee, Dong-Eun; Tran, Dong-Kiem-Lam | Kyungpook Natl Univ, Dept Civil Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Architectural Engn, 80 Daehak Ro, Daegu 41566, South Korea | Tran, Dong-Kiem-Lam/KLY-3827-2024 | 36241850300; 56605563300; 57217738208 | sungpark@knu.ac.kr;dolee@knu.ac.kr;lam.trandongkiem@uah.edu.vn; | GEOMECHANICS AND ENGINEERING | GEOMECH ENG | 2005-307X | 2092-6219 | 37 | 2 | SCIE | ENGINEERING, CIVIL;ENGINEERING, GEOLOGICAL | 2024 | 2.4 | 42.9 | 0 | 2025-05-07 | 0 | 0 | liquefaction resistance of sand; loading frequency; specimen height; specimen size ratio | STATIC LIQUEFACTION; SHEAR; BEHAVIOR; FINES; SOILS; FLOW | liquefaction resistance of sand; loading frequency; specimen height; specimen size ratio | Liquefaction; Cyclic resistance; Height ratio; Liquefaction resistance; Liquefaction resistance of sand; Loading frequencies; Resistance ratio; Size ratio; Specimen height; Specimen size ratio; Specimen sizes; Sand | English | 2024 | 2024-04-25 | 10.12989/gae.2024.37.2.123 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | Efficient recycling strategies for slurry TBM excavated soil | In downtown subway project most of excavated soil is discarded externally, whereas in road construction excavated soil is used as filling material and management of surplus soil becomes important factor for success of the project. Excavated materials from slurry shield TBM are discharged through discharge pipe to slurry treatment plant and excavated soil mixed with bentonite are separated in separation plant by grain size. Fine material has been discarded together in filter cake without recycling. Its volume can vary according to geologic condition but statistically fine material as filter cake is about 5%similar to 30% out of overall excavated volume. However, filter cake is non-toxic and can be recycled when mixed in the appropriate proportions with coarse aggregate. Therefore, in this study, utilization of excavated soil from a slurry shield TBM were examined and labtests were conducted to find the proper way for mixing filter cake and aggregate to be recycled as fill material for road construction | Nam, Sung-Min; Moon, Joon-Shik; Ko, Junyoung; Oh, Hyoungseok | Hyundai Engn & Construct, Dept Civil, Seoul, South Korea; Kyungpook Natl Univ, Dept Civil Engn, 80 Daehak Ro, Daegu 41566, South Korea; Chungnam Natl Univ, Dept Civil Engn, 99 Daehak Ro, Daejeon, South Korea | j.moon@knu.ac.kr; | GEOMECHANICS AND ENGINEERING | GEOMECH ENG | 2005-307X | 2092-6219 | 38 | 6 | SCIE | ENGINEERING, CIVIL;ENGINEERING, GEOLOGICAL | 2024 | 2.4 | 42.9 | 0 | bentonite recycling; fill material for road construction; filter cake recycling; slurry TBM | SHIELD | English | 2024 | 2024-09-25 | 10.12989/gae.2024.38.6.603 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Enhancing High-Rate Charge-Discharge Performance of Lithium-Sulfur Batteries Using Carbon Black Interlayer | In this study, the cathode was coated with Super P, a low-cost conductive carbon, to simplify the process and reduce cost. Electrodes with different sulfur ratios were assembled into cells to characterize their CV curves and impedances. The S0.6-sp cell shows a high discharge capacity of 600 mAh g(-1) at 2 C and 967 mAh g(-1) at 0.5 C. These values are 10% and 25% higher, respectively, compared to S0.53 cells with the same carbon-to-sulfur ratio. Afterward, the S0.6-sp cell was disassembled to observe the suppression of the shuttle effect by confirming the appearance of the separator. In addition, through SEM images, electrode structure collapse caused by the Li2S/Li2S2 layer was insignificant. | Lee, Jae Bin; Min, Gyeonguk; Lim, Won-Gwang; Kang, Hyunchul; Shin, Kyuchul; Yoon, Songhun; Lee, Jinwoo; Joo, Jin | Kyungpook Natl Univ, Dept Hydrogen & Renewable Energy, Daegu 41566, South Korea; Korea Adv Inst Sci & Technol KAIST, Dept Chem & Biomol Engn, 291 Daehak Ro, Daejeon 34141, South Korea; Chung Ang Univ, Sch Integrat Engn, 84 Heukseok Ro, Seoul 06974, South Korea; Kyungpook Natl Univ, Dept Appl Chem, Daegu 41566, South Korea | Lee, Joonseok/AAP-6003-2021 | 57193838726; 57217874626; 57188658399; 57221927010; 14030501800; 7404036205; 56007027600; 57189617034 | yoonshun@cau.ac.kr;jwlee1@kaist.ac.kr;joojin@knu.ac.kr; | KOREAN JOURNAL OF CHEMICAL ENGINEERING | KOREAN J CHEM ENG | 0256-1115 | 1975-7220 | 41 | 4 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;ENGINEERING, CHEMICAL | 2024 | 3.2 | 42.9 | 0 | 2025-05-07 | 0 | 0 | Lithium-sulfur batteries; Carbon black; Cathode coating; Interlayer; Electrochemical performances | LI-S BATTERY; POROUS CARBON; NANOMATERIALS; NANOTUBES; ELECTRODE; GRAPHENE; BARRIER; LAYER; HOST | Carbon black; Cathode coating; Electrochemical performances; Interlayer; Lithium–sulfur batteries | Cathodes; Electric discharges; Lithium; Lithium batteries; Sulfur; Cathode coating; Conductive carbon; Discharge capacities; Electrochemical performance; High rate charge/discharge performance; Interlayer; Lithium/sulfur batteries; Low-costs; Process costs; Reduce costs; Carbon black | English | 2024 | 2024-03 | 10.1007/s11814-024-00057-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Evaluation of durability performance for maintenance of tunnel structures due to repeated freezing and thawing | In this paper, the quantitative evaluation method is presented for the durability performance of mountain tunnel concrete linings experiencing freezing and thawing during winter season. To analyze the freeze-thaw characteristics of lining, the freezing time of the concrete lining was measured by the outside temperature. The heat flow analysis was conducted based on the freezing time measured through the indoor experiment, and based on this, the energy required to freeze the concrete lining by the temperature of the outside air could be analyzed. In addition, the temperature change during the winter season was measured through an instrument installed on the actual tunnel concrete lining, and based on the results of indoor and field experiments, criteria for freeze-thaw environment evaluation and progress evaluation were prepared. Also, an equation using the freezing index was proposed through regression analysis. | An, Jai-Wook; Moon, Joon-Shik; Kim, Hong-Kyoon | KALIS, Environm Social Governance Sect, Chang Won 52856, Gyeongsangnamdo, South Korea; Kyungpook Natl Univ, Dept Civil Engn, 80 Daehak Ro, Daegu 41566, South Korea; KALIS, Dept Ground Safety, Chang Won 52852, Gyeongsangnamdo, South Korea | 56911649100; 57149572000; 57844351600 | j.moon@knu.ac.kr; | GEOMECHANICS AND ENGINEERING | GEOMECH ENG | 2005-307X | 2092-6219 | 38 | 6 | SCIE | ENGINEERING, CIVIL;ENGINEERING, GEOLOGICAL | 2024 | 2.4 | 42.9 | 0.39 | 2025-05-07 | 2 | 1 | criteria development; durability performance; freeze-thaw characteristics; Heat flow analysis; quantitative evaluation method | criteria development; durability performance; freeze-thaw characteristics; Heat flow analysis; quantitative evaluation method | Concretes; Tunnel linings; Concrete linings; Criteria development; Durability performance; Freeze-thaw characteristic; Freeze/thaw; Freezing and thawing; Freezing time; Heat flow analysis; Quantitative evaluation methods; Winter seasons; Thawing | English | 2024 | 2024-09-25 | 10.12989/gae.2024.38.6.593 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Systematic Narrowing of ZIF-8 Apertures via Controlled 2-Ethylimidazole Doping for Hydrogen/Carbon Dioxide Separation | Sodalite (SOD) zeolitic-imidazolate frameworks (ZIFs) with uniform angstrom scale apertures can offer high gas sieving ability for separation applications. Fixed apertures of ZIFs can effectively separate specific gas pair but may not be able to provide similar level of separation for larger or smaller gas pairs. Multivariate (i.e., mixed-linker) ZIFs with controlled linker incorporation can provide desired aperture tuning but difficult to synthesize especially when incorporating linkers that would normally form different structures. Herein, we report a systematic narrowing of SOD ZIF-8 by partially replacing 2-methylimidazole (mIm) linkers of ZIF-8 with 2-ethylimidazole (eIm) via delayed linker addition (DLA) method. Percentages of eIm in the hybrid frameworks were determined to be around 14.3%, 9.1%, and 5.1% for ZIF-8 nuclei formed in 5, 12.5, and 20 min, respectively. Ethyl moiety of eIm restricts framework flexibility of the hybrid ZIF-8, shifts ZIF-8 gate-opening pressure to higher value, and eventually diminishes the gate-opening effect. Polysulfone (PSF)-based mixed-matrix membranes utilizing eIm-doped ZIF-8 as fillers displayed slight reduction in CO2 permeability (18.56 Barrer to 14.85 Barrer) which result in H2/CO2 ideal selectivity improvement. DLA method is expected to work well for other imidazole-based linkers and can perhaps be used to synthesize mixed-linker of other SOD ZIFs. | Yang, Lee; Park, Sunghwan; Han, Wong Zhong; Razak, Musab Abdul; Zhen, Lee Yong; Faires, Muhammed; Omar, Rozita; Choong, Thomas Shean Yeaw; Rohani, Rosiah; Hamid, Mohamad Rezi Abdul | Univ Putra Malaysia, Dept Chem & Environm Engn, Serdang 43400, Selangor, Malaysia; Kyungpook Natl Univ, Convergence Res Ctr Mech & Chem Engn CRCMCE, Dept Energy Chem Engn, Dept Adv Sci & Technol Convergence, Sangju Si 37224, South Korea; Univ Kebangsaan Malaysia, Fac Engn & Built Environm, Dept Chem & Proc Engn, Bangi 43600, Selangor, Malaysia | Razak, Musab/AAK-1412-2020; Hamid, Mohamad/AAG-5950-2021; rohani, rosiah/M-2005-2016 | 59132841100; 56402062100; 59132434400; 38961852200; 59133043500; 59132638700; 9274498300; 6602206037; 24169322700; 57201981848 | m_rezi@upm.edu.my; | KOREAN JOURNAL OF CHEMICAL ENGINEERING | KOREAN J CHEM ENG | 0256-1115 | 1975-7220 | 41 | 8 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;ENGINEERING, CHEMICAL | 2024 | 3.2 | 42.9 | 0.29 | 2025-05-07 | 1 | 1 | Metal-organic frameworks; Zeolitic-imidazole frameworks; Hybrid ZIFs; Mixed-matrix membranes; Gas separations | ZEOLITIC-IMIDAZOLATE FRAMEWORKS; METAL-ORGANIC FRAMEWORKS; MIXED-MATRIX MEMBRANES | Gas separations; Hybrid ZIFs; Metal–organic frameworks; Mixed-matrix membranes; Zeolitic-imidazole frameworks | Gases; Addition method; Gas separations; Gate openings; Hybrid zeolitic-imidazolate framework; Imidazol; Metalorganic frameworks (MOFs); Mixed-matrix membranes; Zeolitic imidazolate framework-8; Zeolitic imidazolate frameworks; Zeolitic-imidazole framework; Gas permeable membranes | English | 2024 | 2024-08 | 10.1007/s11814-024-00192-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A Latent Profile Analysis of Protean Career Attitude and Vocational Identity Status | This study aimed to examine individuals with adaptive protean career attitudes in the current era. Data were obtained from surveying 672 South Korean adults in their 30s and 40s, each with at least one year of work experience. Participants were categorized based on their protean career attitudes and vocational identity status, with subsequent exploration of their relationships with meaning in life, differentiation of self, and resilience. Data analysis involved latent profile analysis, maximum likelihood analysis, and BCH analysis. Results revealed three groups: "diffused wanderer," "organizational adapted citizen," and "protean career identity." The study confirmed the influence of meaning in life and differentiation of self within these profiles, along with differences in resilience. This research offers valuable insights into the characteristics of adaptable individuals based on their "protean career identity." | Moon, Eun Young; Park, Jungkyu; Ka, Yohan | Handong Global Univ, Grad Sch, Dept Psychol, 558 Handong Ro,Heunghae eup, Pohang, Gyeongbuk, South Korea; Kyungpook Natl Univ, Dept Psychol, Daegu, South Korea | 59238503800; 56206565000; 35388483100 | m.eunyoung@gmail.com; | JOURNAL OF CAREER DEVELOPMENT | J CAREER DEV | 0894-8453 | 1556-0856 | 51 | 5 | SSCI | PSYCHOLOGY, APPLIED | 2024 | 2.4 | 43.0 | 0 | 2025-05-07 | 0 | 0 | latent profile analysis; protean career attitudes; vocational identity status; resilience; maximum likelihood; Bolck-Croon-Hagenaars | LIFE; ORIENTATION; INTERPLAY; VARIABLES; MODELS | Bolck–Croon–Hagenaars; latent profile analysis; maximum likelihood; protean career attitudes; resilience; vocational identity status | English | 2024 | 2024-10 | 10.1177/08948453241266801 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Anti-Inflammatory Activity of Labdane and Norlabdane Diterpenoids from Leonurus sibiricus Related to Modulation of MAPKs Signaling Pathway | Leonurus sibiricus, a widely cultivated herbaceous plant in Asian countries, exhibits diverse medicinal applications. Recent studies emphasize its pharmacological properties and efficacy in promoting bone health. In addition to the known compounds and their pharmacological activities, in this study, we isolated and elucidated two new labdane-type diterpenoids, (3 R,5 R,6 S,10 S)-3,6-dihydroxy-15-ethoxy-7-oxolabden-8(9),13(14)-dien-15,16-olide (1) and (4 R,5 R,10 S)-18-hydroxy-14,15-bisnorlabda-8-en-7,13-dione (2), a new natural phenolic compound, and a known compound from L. sibiricus using advanced spectroscopic techniques, including circular dichroism spectroscopy, high-resolution mass spectrometry, and 1- and 2-dimensional NMR. Among these, compound 1 demonstrated potent inhibition of nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) mRNA expression levels, followed by compound 2. Whereas compounds 3 and 4 did not exhibit effectiveness in RAW264.7 macrophages. Moreover, compound 1 suppressed pro-inflammatory markers induced by lipopolysaccharide (LPS) stimulation. Compound 1 also suppressed iNOS and cyclooxygenase-2 (COX-2) protein levels and downregulated pro-inflammatory cytokines. Additionally, compound 1 showed inhibition of the phosphorylation of p38, JNK, and ERK, key mediators of the MAPK signaling pathway. These findings indicate that a natural-derived product, compound 1, might be a potential candidate as an anti-inflammation mediator. © 2024. Thieme. All rights reserved. | Trang, Nguyen Minh; Vinh, Le Ba; Phong, Nguyen Viet; Yang, Seo Young | College of Pharmacy, Chungnam National University, Daejeon, South Korea; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology, Hanoi, Viet Nam; Department of Biology Education, Teachers College, Institute for Phylogenomics and Evolution, Kyungpook National University, Daegu, South Korea; Department of Biology Education, Teachers College, Institute for Phylogenomics and Evolution, Kyungpook National University, Daegu, South Korea | 57413100500; 57190582257; 57205196739; 57215036954 | syy@knu.ac.kr; | Planta Medica | PLANTA MED | 0032-0943 | 1439-0221 | 91 | 1-2 | SCIE | CHEMISTRY, MEDICINAL;INTEGRATIVE & COMPLEMENTARY MEDICINE;PHARMACOLOGY & PHARMACY;PLANT SCIENCES | 2024 | 2 | 43.0 | 0 | 2025-05-07 | 0 | anti-inflammation; labdane diterpenoid; Leonurus sibiricus ; MAPKs | Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Diterpenes; Leonurus; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; 18 hydroxy 14,15 bisnorlabda 8 en 7,13 dione; 3,6 dihydroxy 15 ethoxy 7 oxolabden 8(9),13(14) dien 15,16 olide; antiinflammatory agent; cyclooxygenase 2; diterpenoid; inducible nitric oxide synthase; interleukin 1beta; interleukin 6; mitogen activated protein kinase; mitogen activated protein kinase p38; nitric oxide; norlabdane; stress activated protein kinase; tumor necrosis factor; unclassified drug; antiinflammatory agent; cyclooxygenase 2; diterpenoid; inducible nitric oxide synthase; labdane; lipopolysaccharide; nitric oxide; aerial plant part; animal cell; antiinflammatory activity; Article; carbon nuclear magnetic resonance; cell viability; circular dichroism; controlled study; density functional theory; down regulation; enzyme phosphorylation; heteronuclear multiple bond correlation; in vitro study; Leonurus sibiricus; MAPK signaling; mass spectrometry; mouse; mRNA expression level; MTT assay; nonhuman; nuclear Overhauser effect; proton nuclear magnetic resonance; RAW 264.7 cell line; real time polymerase chain reaction; time dependent density functional theory; animal; chemical structure; chemistry; drug effect; isolation and purification; Leonurus; metabolism | English | Final | 2024 | 10.1055/a-2440-5166 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | atcog8-2, A New Mutant Allele of the Conserved Oligomeric Golgi Complex 8, Reveals the Need for the COG Complex for Gametophyte Development in Arabidopsis | Angiosperms proliferate through double fertilization mediated by male (pollen) and female (embryo sac) gametophytes. To determine the genes essential for pollen development in Arabidopsis thaliana, we first generated a mutant population using an activation tagging vector with herbicide-resistance gene and screened mature pollen phenotypes. Then, a T-DNA insertional heterozygous line was isolated, initially named AP22-48, which produced high levels of abnormal pollen grains. Reciprocal crosses revealed that the genetic transmission of the mutant allele was completely blocked through the male and was highly limited through the female. Determination of T-DNA flanking sequences and genetic complementation of AP22-48 identified AtCOG8, a subunit of the Conserved Oligomeric Golgi (COG) complex, which is a tethering factor essential for the Golgi architecture and retrograde vesicle trafficking in eukaryotes. We renamed the mutant atcog8-2, with reference to a previous cog8 mutant (atcog8-1). While atcog8-1 induced male-specific defects during pollen tube growth, atcog8-2 mutant failed to produce normal gametophytes in both sexes. Detailed morphological analysis demonstrated aberrant development of the pollen and embryo sac in atcog8-2 mutants. This study, thus, strongly suggests that the COG complex functions are broad and indispensable for accurate gametophyte development, which is a prerequisite for sexual reproduction in Arabidopsis. | Oh, Sung Aeong; Nguyen, Tien Dung; Kim, Myung-Hee; Jang, Seonghoe; Park, Soon Ki | Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea; Thai Nguyen Univ, Coll Agr & Forestry, Fac Biotechnol & Food Technol, Thai Nguyen 24000, Vietnam; Natl Inst Agr Sci, Dept Agr Bioresources, Rural Dev Adm, Jeonju 54874, South Korea; World Vegetable Ctr Korea Off, Wonju 55365, Jeolabuk Do, South Korea | 7404104444; 59115396100; 57221718078; 7402219048; 8055974900 | psk@knu.ac.kr; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 67 | 2 | SCIE | PLANT SCIENCES | 2024 | 2 | 43.0 | 0.6 | 2025-05-07 | 1 | 1 | AtCOG8; COG complex; Golgi; Gametophyte; Development; Arabidopsis | CELL; GENE; PROLIFERATION; FERTILIZATION; REPRODUCTION; ORGANIZATION; TRAFFICKING; PROTEINS; STACKS; GROWTH | Arabidopsis; AtCOG8; COG complex; Development; Gametophyte; Golgi | English | 2024 | 2024-04 | 10.1007/s12374-023-09414-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Pollen-Expressed Plant U-Box Protein, OsPUB14 Involves in Rice Fertility and Degrades OsMTD2 | Understanding the intricacies of pollen tube growth in cereal crops, such as rice, is crucial for understanding crossbreeding, seed formation, and crop productivity. In this study, we investigated the molecular mechanisms underlying pollen tube germination and elongation in rice, focusing on the interaction between OsPUB14 and OsMTD2 and its impact on reactive oxygen species (ROS) regulation. Expression studies revealed that OsPUB14 was highly expressed in pollen and anther tissues, indicating its involvement in pollen function. We demonstrated that OsPUB14 belonging to group II U-box domain proteins, interacts with the kinase domain of OsMTD2 (a pollen-specific CrRLK1L member) and degrades it. This interaction subsequently reduces OsMTD2-mediated ROS generation. Moreover, the overexpression of OsPUB14 resulted in decreased ROS levels and reduced fertility in rice plants, emphasizing its role in reproductive processes. Yeast two-hybrid screening identified OsCRK10P and OsNET2D as potential interactors of OsPUB14, further expanding our understanding of the regulatory networks associated with pollen development. This study provides insight into the intricate interplay between pollen-specific plant U-box domain proteins (PUBs), demonstrating their roles in regulating ROS levels and ultimately influencing plant fertility. | Kim, Eun Young; Yun, Sang Dae; Kim, Myung-Hee; Kim, Ji-Hyun; Oh, Sung-Aeong; Lee, Jung Hyun; Son, Ye-Jin; Hong, Woo-Jong; Yun, Chan Mi; Moon, Sunok; Jung, Ki-Hong; Kim, Yu-Jin; Park, Soon Ki | Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea; Kyung Hee Univ, Dept Smart Farm Sci, Yongin 17104, South Korea; Natl Inst Agr Sci, Rural Dev Adm, Dept Agr Bioresources, Genom Div, Jeonju 54874, South Korea; Pusan Natl Univ, Life & Ind Convergence Res Inst, Dept Life Sci & Environm Biochem, Miryang 50463, South Korea; Kyung Hee Univ, Crop Biotech Inst, Grad Sch Green Biosci, Yongin 17104, South Korea | Hong, Woo-Jong/HPF-0756-2023; Jung, Ki/L-5570-2019 | 58353459000; 57210883667; 57221718078; 59642475200; 7404104444; 57219322810; 59257760500; 57194418669; 59331452800; 7401616474; 56022522000; 57074286200; 8055974900 | ableyoung@naver.com;yungold63@naver.com;running4859@gmail.com;jihyun0_0@pusan.ac.kr;aeongoh@knu.ac.kr;jkjk0802@naver.com;sonyeeejin921@gmail.com;hwj0602@khu.ac.kr;chanmi1017@naver.com;moonsun@khu.ac.kr;khjung2010@khu.ac.kr;yjkim2020@pusan.ac.kr;psk@knu.ac.kr; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 67 | 5 | SCIE | PLANT SCIENCES | 2024 | 2 | 43.0 | 0.6 | 2025-05-07 | 0 | 1 | Rice; Plant U-box domain protein (PUB); Reactive oxygen species (ROS); Protein degradation; Fertility | E3 UBIQUITIN LIGASE; CELLS | Fertility; Plant U-box domain protein (PUB); Protein degradation; Reactive oxygen species (ROS); Rice | English | 2024 | 2024-10 | 10.1007/s12374-024-09441-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | An induced pluripotent stem cell-based approach for hair follicle development and regeneration | Because hair loss is a common concern for many individuals, potential regenerative therapies of hair follicles have been extensively researched. Induced pluripotent stem cells (iPSCs) are a promising avenue for hair follicle regeneration. This review explores current iPSC-based approaches and highlights their potential applications and challenges in hair restoration. The principles of iPSC technology, iPSC differentiation into hair follicle precursor cells, and potential clinical implications for hair follicle regeneration are also discussed. This overview of iPSCs and their applications aims to contribute to our understanding of their role in hair restoration and potential future therapeutic applications. (c) 2024 The Author(s). Published by Elsevier BV on behalf of The Japanese Society for Regenerative Medicine. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/). | Sivamani, Poornima; Rajendran, Ramya Lakshmi; Gangadaran, Prakash; Ahn, Byeong-Cheol | Christian Med Coll & Hosp, Dept Pharmacol & Clin Pharmacol, Vellore, India; Kyungpook Natl Univ, Sch Med, Dept Nucl Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 FOUR KNU Convergence Educ Program Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Nucl Med, Daegu 41944, South Korea | Rajendran, Ramya/AAV-6338-2021; Gangadaran, Prakash/AAV-3102-2021 | 49061497000; 57195318729; 54393130400; 7202791511 | prakashg@knu.ac.kr;abc2000@knu.ac.kr; | REGENERATIVE THERAPY | REGEN THER | 2352-3204 | 26 | SCIE | CELL & TISSUE ENGINEERING;ENGINEERING, BIOMEDICAL | 2024 | 3.5 | 43.1 | 0.2 | 2025-05-07 | 2 | 2 | Hair loss; iPSCs; Hair follicle regeneration; Organoids; 3D culture | GENERATION; THERAPY | 3D culture; Hair follicle regeneration; Hair loss; iPSCs; Organoids | cell differentiation; drug administration; drug analysis; hair follicle; hair loss; human; human cell; induced pluripotent stem cell; nonhuman; organoid; ovary follicle development; regeneration; review; stem cell; therapy | English | 2024 | 2024-06 | 10.1016/j.reth.2024.07.005 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Extracellular vesicle mimetics engineered from mesenchymal stem cells and curcumin promote fibrosis regression in a mouse model of thioacetamide-induced liver fibrosis | Recent research suggests that advanced liver fibrosis could be reversed, but the therapeutic agents needed for the prevention of liver fibrosis remain to be elucidated. The beneficial effects of mesenchymal stem cells (MSCs) and MSC-derived extracellular vesicles (EVs) on liver fibrosis have been reported. However, the large-scale production of MSC-EVs remains challenging. The present study investigated the therapeutic effects of mouse MSC-derived EV mimetics (MEVMs) in combination with curcumin (antifibrotic compound) using a mouse model of thioacetamide-induced liver fibrosis. MEVMs were prepared through the serial extrusion of MSCs. These MEVMs were similar in size and morphology to the EVs. The biodistribution study showed that fiuorescently labeled MEVMs predominantly accumulated in the liver. The establishment of liver fibrosis was confirmed via increased collagen (histology), liver fibrosis score, a-smooth muscle actin (a-SMA), and vimentin proteins levels. Treatment with MEVMs, curcumin, or their combination decreased the amount of collagen in liver tissues, with the antifibrotic effects of MEVMs being further confirmed by the liver fibrosis score. All treatments decreased the expression of collagen 1a, a-SMA, and vimentin. MEVMs showed superior effects than curcumin. Thus, MSC-derived EVMs could be a potential alternative for the treatment of liver fibrosis. (c) 2024 Japanese Society of Regenerative Medicine. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | Gopal, Arunnehru; Gangadaran, Prakash; Rajendran, Ramya Lakshmi; Oh, Ji Min; Lee, Ho Won; Hong, Chae Moon; Kalimuthu, Senthilkumar; Han, Man-Hoon; Lee, Jaetae; Ahn, Byeong-Cheol | Kyungpook Natl Univ, Sch Med, Dept Nucl Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Nucl Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pathol, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Pathol, Daegu 41944, South Korea; Swamy Vivekanandha Med Coll Hosp & Res Inst, Cent Res Lab, Namakkal 637205, Tamil Nadu, India | ; Rajendran, Ramya/AAV-6338-2021; Gangadaran, Prakash/AAV-3102-2021 | 57203278478; 54393130400; 57195318729; 57190370462; 35337240700; 37050876700; 54794141400; 57194067936; 7601451907; 7202791511 | abc2000@knu.ac.kr; | REGENERATIVE THERAPY | REGEN THER | 2352-3204 | 26 | SCIE | CELL & TISSUE ENGINEERING;ENGINEERING, BIOMEDICAL | 2024 | 3.5 | 43.1 | 0.9 | 2025-05-07 | 3 | 3 | Extracellular vesicles-mimetics; Mesenchymal stem cells; Liver fibrosis; Curcumin | HEPATIC STELLATE CELLS; INHIBITOR; INJURY; DIFFERENTIATION; APOPTOSIS; PRESSURE; PROTECTS; MICE | Curcumin; Extracellular vesicles-mimetics; Liver fibrosis; Mesenchymal stem cells | curcumin; peroxisome proliferator activated receptor gamma; thioacetamide; animal cell; animal experiment; animal model; animal tissue; Article; bone marrow mesenchymal stem cell; controlled study; density gradient centrifugation; drug induced disease; hepatic stellate cell; histopathology; immunofluorescence assay; immunohistochemistry; liver fibrosis; male; mesenchymal stem cell; mouse; nonhuman; protein expression; reverse transcription polymerase chain reaction; RNA isolation; scanning electron microscopy; thioacetamide induced liver fibrosis; transmission electron microscopy; ultraviolet spectrophotometry; Western blotting | English | 2024 | 2024-06 | 10.1016/j.reth.2024.10.005 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | South Korean Provincial Government's Introduction of the International Baccalaureate and Its Educational Effects on Middle School Students: A Grounded Theory Study | In South Korea, the International Baccalaureate (IB) Middle Years Programme (MYP) has been implemented in public education for several years. This article explores the IB MYP's characteristics and educational effects by adopting the grounded theory research approach of Corbin and Strauss (1990, 2015). A total of 27 students from three public middle schools offering the IB MYP in one Korean city participated in interviews. Through the interviews, 151 concepts, 41 sub-categories, and 22 categories were identified. Compared to conventional Korean education, the IB MYP's noticeable traits include student-centered classes, inquiry-based learning, interdisciplinary subjects, writing-centered tests, and an emphasis on the IB learner profile. While these differences may initially pose difficulties for Korean students, they can lead to positive outcomes in the cognitive and affective domains, as well as in interpersonal relationships. Based on the findings, it is recommended that the Korean provincial government should develop a long-term vision both nationally and internationally. | Lee, Jieun; Ryu, Youngchul | Kyungpook Natl Univ, Daegu, South Korea; Busan Univ Foreign Studies, Busan 46234, South Korea | 55689967800; 59424540300 | sun072@bufs.ac.kr; | JOURNAL OF RESEARCH IN INTERNATIONAL EDUCATION | J RES INT EDUC | 1475-2409 | 1741-2943 | 23 | 3 | ESCI | EDUCATION & EDUCATIONAL RESEARCH | 2024 | 1.4 | 43.1 | 0 | 2025-05-07 | 0 | 0 | International Baccalaureate; Middle Years Programme; public education; education in Korea; grounded theory | PROGRAM | education in Korea; grounded theory; International Baccalaureate; Middle Years Programme; public education | English | 2024 | 2024-12 | 10.1177/14752409241303184 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Association between severity of pancreatic exocrine insufficiency and computed tomography-based morphological severity in patients with chronic pancreatitis | The association between pancreatic exocrine insufficiency (PEI) and morphologic findings in chronic pancreatitis has not yet been fully studied. Thus, the aim of this study was to investigate the correlation between PEI severity and computed tomography (CT)-based morphological severity in patients with chronic pancreatitis. This nationwide survey included 180 Korean participants with chronic pancreatitis aged 18 years or older between January 2018 and December 2021. PEI severity was measured by the PEI questionnaire (PEI-Q). Morphological severity was measured using a CT-based scoring system, which included pancreatic duct caliber, pancreatic duct stricture or intraductal obstructing calculus, pancreatic atrophy, and pancreatic calcification. In addition, 35 patients who received pancreatic enzyme replacement therapy (PERT) were evaluated by PEI-Q to determine whether PEI improved after PERT. PEI severity was normal (n = 89), mild (n = 69), moderate (n = 14), or severe (n = 8). Severities of pancreatic duct caliber and pancreatic duct stricture or intraductal obstructing calculus had small but significant associations with PEI severity (Cramer V = 0.121 and 0.141, respectively). Severities of pancreatic atrophy and pancreatic calcification were not significantly associated with PEI severity. PEI severity showed a significant improvement after PERT (P < .001). In conclusion, PEI severity had significant associations with CT-based morphological severities, including severities of pancreatic duct caliber and pancreatic duct stricture or intraductal obstructing calculus. In addition, PEI-Q could be a useful indicator for evaluating the therapeutic effect of PERT in clinical practice. | Lee, Jae Min; Lee, Sang Hyub; Choi, Young Hoon; Han, Sung Yong; Jo, Jung Hyun; Choe, Jung Wan; Kim, Eui Joo; Jang, Dong Kee; Jung, Min Kyu | Gyeongsang Natl Univ, Gyeongsang Natl Univ Changwon Hosp, Dept Internal Med, Coll Med, Chang Won, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Liver Res Inst, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med, Seoul, South Korea; Pusan Natl Univ, Pusan Natl Univ Hosp, Biomed Res Inst, Dept Internal Med,Sch Med, Busan, South Korea; Yonsei Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Korea Univ, Coll Med, Korea Univ Ansan Hosp, Dept Internal Med, Ansan, South Korea; Gachon Univ, Gil Med Ctr, Dept Internal Med, Coll Med, Incheon, South Korea; Seoul Natl Univ, Coll Med, Dept Internal Med, Boramae Med Ctr, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea | KANG, MIN KYU/ACI-8824-2022; Kim, Eui/P-8348-2019; Jo, Jung Hyun/V-8316-2019 | 56557482500; 36062488800; 57212256431; 57190127827; 55532796800; 56481120200; 36102878900; 56091787300; 56783168100 | 01179jm@naver.com;gidoctor@snu.ac.kr;crzyzs@naver.com;mirsaint@hanmail.net;junghyunjo83@yuhs.ac;jwchoe@korea.ac.kr;imetkim@gilhospital.com;mapmotive@hanmail.net;minky1973@hanmail.net; | MEDICINE | MEDICINE | 0025-7974 | 1536-5964 | 103 | 48 | SCIE | MEDICINE, GENERAL & INTERNAL | 2024 | 1.4 | 43.2 | 0 | 2025-05-07 | 0 | 0 | chronic pancreatitis; computed tomography; pancreatic exocrine insufficiency | ENZYME REPLACEMENT THERAPY | chronic pancreatitis; computed tomography; pancreatic exocrine insufficiency | Adult; Aged; Enzyme Replacement Therapy; Exocrine Pancreatic Insufficiency; Female; Humans; Male; Middle Aged; Pancreas; Pancreatic Ducts; Pancreatitis, Chronic; Republic of Korea; Severity of Illness Index; Tomography, X-Ray Computed; abdominal pain; adult; aged; alcohol consumption; Article; atrophy; body mass; chronic pancreatitis; computer assisted tomography; controlled study; diabetes mellitus; digestive system disease assessment; disease association; disease severity; endoscopic ultrasonography; enzyme replacement; exocrine pancreatic insufficiency; female; human; major clinical study; male; medical history; nuclear magnetic resonance imaging; observational study; pancreas calcification; pancreas disease; pancreatic duct; pancreatic exocrine insufficiency questionnaire; prevalence; prospective study; recurrent disease; risk factor; scoring system; smoking; steatorrhea; stenosis; complication; diagnostic imaging; enzyme replacement; epidemiology; exocrine pancreatic insufficiency; middle aged; pancreas; pathology; procedures; severity of illness index; South Korea; x-ray computed tomography | English | 2024 | 2024-11-29 | 10.1097/md.0000000000040737 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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