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| ○ | ○ | Review | Hypomethylating agent-based post-transplant strategies to maximize the outcome of high-risk acute myeloid leukemia after allogeneic stem cell transplantation | Introduction Clinical outcomes of patients diagnosed with high-risk acute myeloid leukemia (AML) are poor, and relapse or refractoriness is main cause of treatment failure, even in those who underwent standard allogeneic stem cell transplantation (allo-SCT). Therefore, innovative or additional approaches are necessary to overcome refractoriness to the graft-versus-leukemia (GVL) effect immediately after allo-SCT. Areas covered Hypomethylating agents (HMA) present a feasible option that can be adopted during the post-transplant phase. Moreover, combination strategies based on HMA may induce a synergistic effect by promoting anti-leukemic effects that overcome residual leukemic burden, and it is a well-tolerated therapeutic option for high-risk disease. Relevant literatures published in the last 30 years were searched from PubMed to review the topic of AML, allo-SCT, and HMAs. Expert opinion Post-transplant therapy is strongly needed to improve the outcomes of allogeneic transplantation for certain AML patients classified with high-risk disease. In that sense, prophylactic and preemptive HMAs are a promising additive therapy for allogeneic recipients. | Baek, Dong Won; Kim, Juhyung; Cho, Hee Jeong; Moon, Joon Ho; Sohn, Sang Kyun | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Hematol Oncol, Daegu 41944, South Korea | 57191874272; 58739544500; 57216754907; 56568642700; 13310226800 | sksohn@knu.ac.kr; | EXPERT REVIEW OF HEMATOLOGY | EXPERT REV HEMATOL | 1747-4086 | 1747-4094 | 13 | 9 | SCIE | HEMATOLOGY | 2020 | 2.929 | 65.1 | 0.04 | 2025-06-25 | 1 | 1 | High-risk; acute myeloid leukemia; allogeneic stem cell transplantation; hypomethylating agent; minimal residual disease | DONOR LYMPHOCYTE INFUSIONS; ACUTE MYELOGENOUS LEUKEMIA; LOW-DOSE AZACITIDINE; REGULATORY T-CELLS; RETROSPECTIVE MULTICENTER ANALYSIS; CONVENTIONAL CARE REGIMENS; DNA METHYLATION; MYELODYSPLASTIC SYNDROME; OLDER PATIENTS; MAINTENANCE THERAPY | acute myeloid leukemia; allogeneic stem cell transplantation; High-risk; hypomethylating agent; minimal residual disease | Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Combined Modality Therapy; Decitabine; DNA Methylation; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Postoperative Care; Transplantation, Homologous; Treatment Outcome; antileukemic agent; antineoplastic agent; azacitidine; busulfan; cytarabine; decitabine; fludarabine; hypomethylating agent; idarubicin; unclassified drug; antineoplastic agent; azacitidine; CD135 antigen; decitabine; FLT3 protein, human; acute myeloid leukemia; adult; allogeneic hematopoietic stem cell transplantation; antileukemic activity; blast cell; bone marrow cell; case report; clinical article; cytogenetics; disease burden; donor lymphocyte infusion; gene mutation; high risk patient; human; male; middle aged; multiple cycle treatment; myeloablative conditioning; platelet count; priority journal; Review; synergistic effect; treatment outcome; treatment planning; acute myeloid leukemia; adverse event; allotransplantation; DNA methylation; drug effect; genetics; hematopoietic stem cell transplantation; mortality; multimodality cancer therapy; mutation; postoperative care; procedures | English | 2020 | 2020-09-01 | 10.1080/17474086.2020.1804355 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Large-strain consolidation analysis of PVD-installed soft soil considering the discharge capacity variation according to depth and time | Purpose: The consolidation behavior of prefabricated vertical drain (PVD)-installed soft deposits mainly depends on the PVD performance. The purpose of this study is to propose a numerical solution for the consolidation of PVD-installed soft soil using the large-strain theory, in which the reduction of discharge capacity of PVD according to depth and time is simultaneously considered. Design/methodology/approach: The proposed solution also takes into account the general constitute relationship of soft soil. Subsequently, the proposed solution is applied to analyze and compare with the monitoring data of two cases, one is the experimental test and another is the test embankment in Saga airport. Findings: The results show that the reduction of PVD discharge capacity according to depth and time increased the duration required to achieve a certain degree of consolidation. The consolidation rate is more sensitive to the reduction of PVD discharge capacity according to time than that according to the depth. The effects of the reduction of PVD discharge capacity according to depth are more evident when PVD discharge capacity decreases. The predicted results using the proposed numerical solution were validated well with the monitoring data for both cases in verification. Research limitations/implications: In this study, the variation of PVD discharge capacity is only considered in one-dimensional consolidation. However, it is challenging to implement a general expression for discharge capacity variation according to time in the two-dimensional numerical solution (two-dimensional plane strain model). This is the motivation for further study. Practical implications: A geotechnical engineer could use the proposed numerical solution to predict the consolidation behavior of the drainage-improved soft deposit considering the PVD discharge capacity variation. Originality/value: The large-strain consolidation of PVD-installed soft deposits could be predicted well by using the proposed numerical solution considering the PVD discharge capacity variations according to depth and time. © 2020, Emerald Publishing Limited. | Nguyen, Ba-Phu; Pradhan, Ananta Man Singh; Nguyen, Tan Hung; Doan, Nhat-Phi; Nguyen, Van-Quang; Huynh, Thanh-Canh | Department of Civil Engineering, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Viet Nam; Water Resource Research and Development Centre, Ministry of Energy, Water Resources and Irrigation, Government of Nepal, Kathmandu, Nepal; Department of Civil Engineering, Can Tho University of Technology, Can Tho, Viet Nam; Department of Civil Engineering, Kyungpook National University, Daegu, South Korea; Department of Civil and Environment Engineering, Hanyang University, Seoul, South Korea, Department of Civil Engineering, Vinh University, Vinh, Viet Nam; Department of Civil Engineering, Duy Tan University, Da Nang, Viet Nam, Center for Construction, Mechanics and Materials, Institute of Research and Development, Duy Tan University, Da Nang, Viet Nam | 57202113615; 55488606600; 57204362603; 58095587400; 57205661646; 55516115900 | nguyenbaphu@iuh.edu.vn; | Engineering Computations (Swansea, Wales) | ENG COMPUTATION | 0264-4401 | 1758-7077 | 38 | 4 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, MULTIDISCIPLINARY;MATHEMATICS, INTERDISCIPLINARY APPLICATIONS;MECHANICS | 2020 | 1.593 | 65.3 | 0.48 | 2025-06-25 | 15 | Consolidation; Discharge capacity; Large-strain theory; Prefabricated vertical drain; Soft soil | Deposits; Drainage; Embankments; Geotechnical engineering; Monitoring; Soils; Degree of consolidations; Design/methodology/approach; Discharge capacities; Large strain consolidation; Numerical solution; One dimensional consolidation; Prefabricated vertical drains; Two-dimensional plane strain model; Strain | English | Final | 2020 | 10.1108/ec-05-2020-0253 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Theoretical DFT interpretation of infrared spectra of biologically active arabinogalactan sulphated derivatives | Arabinogalactan (AG) and sulphated arabinogalactans which are products of chemical modification of arabinogalactan polysaccharide with anticoagulant properties were studied by experimental infrared (IR) spectroscopy combined with density functional theory simulations. Mutual analysis of experimental and theoretical IR frequencies indicates that the discrepancies between experiment and theory is caused by the influence of -OH groups, which led to the energy shift and broadening of the absorption IR bands. It was found that theoretical and experimental spectra correspond well within the 3000-4000 cm(-1) spectral region. Addition of sulphur group in AG structure causes hydroxyl group to become accessible for further sulphation. The difference between experimental and theoretical IR frequencies of sulphated AG derivatives is greater than that of the parent arabinogalactan due to the increase in the number of possible isomers and conformers. | Kazachenko, Aleksandr S.; Tomilin, Felix N.; Pozdnyakova, Anastasia A.; Vasilyeva, Natalia Yu; Malyar, Yuriy N.; Kuznetsova, Svetlana A.; Avramov, Pavel, V | FRC Krasnoyarsk Sci Ctr SB RAS, Inst Chem & Chem Technol SB RAS, 50-24 Akademgorodok, Krasnoyarsk 660036, Russia; Siberian Fed Univ, 79 Svobodny Pr, Krasnoyarsk 660041, Russia; FRC Krasnoyarsk Sci Ctr SB RAS, Kirensky Inst Phys SB RAS, 50-38 Akademgorodok, Krasnoyarsk 660036, Russia; Natl Res Tomsk State Univ, Lenin Ave 36, Tomsk 634050, Russia; Kyungpook Natl Univ, Dept Chem, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, 80 Daehak Ro, Daegu 41566, South Korea | Казаченко, Александр/AAP-4251-2020; Tomilin, Felix/F-3763-2014; Vasilyeva, Natalia/AAE-1865-2022; Malyar, Yuriy/E-3940-2014 | 57200968620; 6602246772; 57217067468; 57200545459; 55674311600; 7103182089; 7004322420 | leo_lion_leo@mail.ru; | CHEMICAL PAPERS | CHEM PAP | 2585-7290 | 1336-9075 | 74 | 11 | SCIE | CHEMISTRY, MULTIDISCIPLINARY | 2020 | 2.097 | 65.5 | 1.37 | 2025-06-25 | 29 | 27 | Arabinogalactan; Sulphated arabinogalactan; FTIR-spectra; Molecular structure; Density functional theory | DENSITY-FUNCTIONAL THEORIES; ASTRAGALUS POLYSACCHARIDE; ANTICOAGULANT ACTIVITY; NMR-SPECTROSCOPY; SIBERIAN LARCH; RAMAN; GLYCOSAMINOGLYCANS; REACTIVITY; SET | Arabinogalactan; Density functional theory; FTIR-spectra; Molecular structure; Sulphated arabinogalactan | English | 2020 | 2020-11 | 10.1007/s11696-020-01220-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | An efficient synthetic approach towards a single diastereomer of (2R,3R)-N²,N³-bis((S)-1-phenylethyl)butane-2,3-diamine via metalation and demetalation | A facile synthetic approach has been adopted towards the synthesis of (2R,3R)-N-2,N-3-bis((S)-1-phenylethyl)butane-2,3-diamine via demetalation of its dichloro Zn(II) complex, which itself was separated from a mixture of diastereomeric Zn(II) complexes by fractional crystallization. The synthesized chiral 1,2-diamine ligand was evaluated as a chiral auxiliary for the Cu(II)-catalysed asymmetric Henry reaction of 3-phenylpropanal and nitromethane, yielding (S)-1-nitro-4-phenylbutan-2-ol in excellent yields (up to 99%) and enantioselectivities (up to 97%). Graphic abstract A facile synthetic approach towards (2R,3R)-N-2,N-3-bis((S)-1-phenylethyl)butane-2,3-diamine (2b) via fractional crystallization and demetalation of its Zn(II) complex has been adopted. 2b served as a highly enantioselective pro-ligand with Cu(OAc)(2) for asymmetric Henry reaction of 3-phenylpropanal and nitromethane in the presence of base with 97% > ee and 99% yield. | Cho, Juhyun; Nayab, Saira; Jeong, Jong Hwa | Kyungpook Natl Univ, Dept Chem, 1370 Sankyuk Dong, Taegu 702701, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, 1370 Sankyuk Dong, Taegu 702701, South Korea; Shaheed Benazir Bhutto Univ, Dept Chem, Dir Upper, Khyber Pakhtunk, Pakistan | Nayab, Saira/JBS-3013-2023 | 57198450723; 36490286400; 7402045988 | drnayab@sbbu.edu.pk;jeongjh@knu.ac.kr; | TRANSITION METAL CHEMISTRY | TRANSIT METAL CHEM | 0340-4285 | 1572-901X | 45 | 1 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR | 2020 | 1.588 | 65.6 | 0 | 2025-06-25 | 1 | 1 | X-RAY STRUCTURES; STEREOSELECTIVE POLYMERIZATION; STRUCTURAL-CHARACTERIZATION; ASYMMETRIC CATALYSIS; VICINAL DIAMINES; COMPLEXES; LIGANDS; DERIVATIVES; CU(II); ZN | Butane; Copper compounds; Enantioselectivity; Ligands; Synthesis (chemical); Asymmetric Henry reactions; Chiral auxiliaries; Demetalation; Diastereomeric; Diastereomers; Enantioselective; Fractional crystallization; Synthetic approach; Zinc compounds | English | 2020 | 2020-01 | 10.1007/s11243-019-00351-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | An endophytic fungus Aspergillus violaceofuscus can be used as heat stress adaptive tool for Glycine max L. and Helianthus annuus L. | High temperature is one of the leading threats to the plants that severely affects crop quality as well as quantity. Endophytic fungi might be a new tool to safeguard crops against the perilous effects of global warming In this context, we isolated a thermal stress mitigating endophytic fungus from the fern Dryopteris filix L. The phylogenetic study and 18S rRNA sequence similarity confirmed the potential strain as Aspergillus violaceofuscus. The culture filtrate of A. violaceofuscus exhibited higher concentration of secondary metabolites that enhanced the total chlorophyll content, plant height and biomass of sunflower and soybean seedlings under heat stress. Conversely, the A. violaceofuscus associated plants achieved low levels of reactive oxygen species, abscisic acid, catalase, ascorbic acid oxidase, proline and an overall improved the nutritional value. The current study suggests that A. violaceofuscus can be used as heat stress adaptive tool in crops to achieve sustainable agriculture. | Ismail; Hamayun, Muhammad; Hussain, Anwar; Khan, Sumera Afzal; Iqbal, Amjad; Lee, In-Jung | Abdul Wali Khan Univ Mardan, Dept Bot, Mardan, Pakistan; Univ Peshawar, Ctr Biotechnol & Microbiol, Peshawar, Pakistan; Abdul Wali Khan Univ Mardan, Dept Food Sci & Technol, Mardan, Pakistan; Kyungpook Natl Univ, Sch Appl Biosci, Daegu, South Korea | Hussain, Anwar/N-1605-2019; Hamayun, Muhammad/B-1694-2010; Iqbal, Amjad/E-2010-2014; Lee, In-Jung/GLS-0432-2022; Khan, Abdul/H-5910-2011 | hamayun@awkum.edu.pk;ijlee@knu.ac.kr; | JOURNAL OF APPLIED BOTANY AND FOOD QUALITY | J APPL BOT FOOD QUAL | 1439-040X | 93 | SCIE | PLANT SCIENCES | 2020 | 1.451 | 65.7 | 18 | endophytic fungi; global warming; Aspergillus violaceofuscus; Dryopteris filix.; antioxidants; heat stress | PLANT-GROWTH; RAPID-DETERMINATION; ACID; GIBBERELLINS; PROLINE | English | 2020 | 2020 | 10.5073/jabfq.2020.093.014 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
| ○ | ○ | Article | Ultracompact Plasmonic Meta-pixel for Arbitrary Polarization Detection | Polarization of light is a fundamental characteristic which represents the oscillation of electric fields in electromagnetic optics. The utilization of polarization gives opportunities to analyze the light-matter interaction or improve the performance of optical devices. Miniaturization of polarimeter consisting of bulky optical components is an important challenge for applying to integrated photonic chips or sensors. In this letter, we propose a compact plasmonic polarimeter with six different plasmonic lenses for detecting Stokes parameters in near field. Each plasmonic lens, which focuses plasmonic fields under the specific polarization incidence, can be designed by pairs of nanoslit with different configurations. We theoretically and numerically show that the intensities of plasmonic focal spots can derive full Stokes parameter. We expect that the proposed work can contribute to miniaturization and integration of polarimeter. | Moon, Seong-Won; Lee, Seung Yeol | Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu 41566, South Korea | Lee, Seungwoo/U-8056-2017 | 57214123350; 55881869300 | seungyeol@knu.ac.kr; | PLASMONICS | PLASMONICS | 1557-1955 | 1557-1963 | 15 | 6 | SCIE | CHEMISTRY, PHYSICAL;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY | 2020 | 2.404 | 65.7 | 0.23 | 2025-06-25 | 3 | 3 | Surface plasmon polariton; Stokes parameter; Polarimeter; Metasurface; Plasmonic lens | SPIN-ORBIT INTERACTION; METASURFACE; NANOSLITS; ABSORBER | Metasurface; Plasmonic lens; Polarimeter; Stokes parameter; Surface plasmon polariton | English | 2020 | 2020-12 | 10.1007/s11468-020-01201-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Higher fatty liver index is associated with increased risk of new onset heart failure in healthy adults: a nationwide population-based study in Korea | BackgroundHeart failure (HF) is relatively common cardiovascular disease with high mortality and morbidity. Although it is associated with many cardiovascular risk factors, the association between nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, and HF has not been evaluated in a large-scale cohort study. Thus, we evaluated the ability of the fatty liver Index (FLI), a surrogate marker of NAFLD, to predict the development of HF in healthy individuals.MethodsWe analyzed the association between the FLI and new-onset HF with multivariate Cox proportional-hazards models in 308,578 healthy persons without comorbidities who underwent the National Health check-ups in the republic of Korea from 2009 to 2014.ResultsA total of 2532 subjects (0.8%) were newly diagnosed with HF during the study period (a median of 5.4years). We categorized our subjects into quartile groups according to FLI (Q1, 0-4.9; Q2, 5.0-12.5; Q3, 12.6-31.0; and Q4, >31.0). The cumulative incidence of HF was significantly higher in the highest FLI group than in the lowest FLI group (Q1, 307 [0.4%] and Q4, 890 [1.2%]; P<0.001). Adjusted hazard ratio (HRs) indicated that the highest FLI group was independently associated with an increased risk for HF (HR between Q4 and Q1, 2.709; 95% confidence interval=2.380-3.085; P<0.001). FLI was significantly associated with an increased risk of new-onset HF regardless of their baseline characteristics.ConclusionsHigher FLI was independently associated with increased risk of HF in a healthy Korean population. | Roh, Jae-Hyung; Park, Jae-Hyeong; Lee, Hanbyul; Yoon, Yong-Hoon; Kim, Minsu; Kim, Yong-Giun; Park, Gyung-Min; Lee, Jae-Hwan; Seong, In-Whan | Chungnam Natl Univ, Chungnam Natl Univ Hosp, Sch Med, Dept Cardiol Internal Med, 282 Munhwa Ro, Daejeon 35015, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Univ Ulsan, Coll Med, Ulsan Univ Hosp, Dept Cardiol, Ulsan, South Korea | ; Park, Jae-Hyeong/AAD-9015-2021; Lee, Yoon/ABA-8808-2020; Park, M.J./Y-5611-2019 | 57216309871; 36063048400; 59107079300; 56038479700; 57208554686; 57207444006; 25924423800; 36066387900; 35254371300 | jaehyeongpark@gmail.com; | BMC CARDIOVASCULAR DISORDERS | BMC CARDIOVASC DISOR | 1471-2261 | 20 | 1 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 2.298 | 65.9 | 1.65 | 2025-06-25 | 26 | 26 | Fatty liver index; Non-alcoholic fatty liver disease; Heart failure; Healthy people programs | GAMMA-GLUTAMYL-TRANSFERASE; CARDIOVASCULAR-DISEASE; INSULIN-RESISTANCE; FIBROSIS; DYSFUNCTION; NAFLD; HYPERTENSION; STEATOSIS; DIAGNOSIS; PROGNOSIS | Fatty liver index; Healthy people programs; Heart failure; Non-alcoholic fatty liver disease | Adult; Databases, Factual; Female; Healthy People Programs; Heart Failure; Humans; Incidence; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Republic of Korea; Risk Assessment; Risk Factors; Time Factors; adult; aged; Article; cohort analysis; comorbidity; controlled study; disease association; disease course; fatty liver; female; heart failure; human; incidence; Korea; major clinical study; male; medical examination; middle aged; nonalcoholic fatty liver; population research; prediction; priority journal; risk factor; factual database; health promotion; heart failure; nonalcoholic fatty liver; risk assessment; risk factor; South Korea; time factor | English | 2020 | 2020-04-28 | 10.1186/s12872-020-01444-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Molecular characteristics of antimicrobial resistance determinants and integrons in Salmonella isolated from chicken meat in Korea | The increase and spread of antimicrobial resistance, particularly multidrug resistance (MDR), in Salmonella isolated from food animal pose a serious public health concern worldwide. Therefore, the objective of this study was to characterize antimicrobial resistance and analyze the transferability of integrons and antimicrobial resistance genes in MDR Salmonella isolates from retail chicken meat in Korea. Among the 57 Salmonella isolates, 43 (75.4%) showed resistance to at least 1 antimicrobial agent and 29 (50.9%) exhibited MDR. The highest resistance was to nalidixic acid (73.7%), ampicillin (50.9%), tetracycline (42.1%), chloramphenicol (33.3%), and trimethoprim/sulfamethoxazole (33.3%). beta-lactamase-encoding genes were detected in 9 (31.0%) of 29 beta-lactam-resistant isolates. These genes were as follows: bla(CMY-2) (1 S. Albany), bla(CTX-M-79) (1 S. Virchow), and bla(CTX-M-15) (6 S. Virchow and 1 S. Enteritidis). Seventeen (70.8%) of the 24 tetracycline-resistant isolates harbored only tetA. Among the 19 trimethoprim/sulfamethoxazole-resistant isolates, sul1 was only identified in 3 (68.4%) isolates. cmlA was detected in 4 (21.1%) of the 19 chloramphenicol-resistant isolates. Both aminoglycoside-resistant isolates were positive for ant(2 '')-I. Class 1 integrons were observed in 28 (49.1%) isolates belonging to S. Albany (21 isolates), S. Virchow (6 isolate), and S. Enteritidis (1 isolate). All 29 MDR isolates carried one or more integrons and antimicrobial resistance genes. All isolates harboring the ESBL and pAmpC genes exhibited resistance to at least 4 different classes of antimicrobials, including cephalosporins and noncephalosporins. Furthermore, most (79.3%) of the MDR isolates carried 1 or 2 of conjugable plasmids, and the transfer of integrons and resistance genes via plasmids was confirmed in transconjugants, which showed resistance patterns similar to those of the donor strains. | Sin, M.; Yoon, S.; Kim, Y. B.; Noh, E. B.; Seo, K. W.; Lee, Y. J. | Kyungpook Natl Univ, Dept Publ Hlth, Coll Vet Med, Daegu 41566, South Korea; Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA | ; Yoon, Sunghyun/AAL-4806-2021 | 57216180664; 57216037473; 57200044764; 57209844683; 57203233812; 56612134500 | youngju@knu.ac.kr; | JOURNAL OF APPLIED POULTRY RESEARCH | J APPL POULTRY RES | 1056-6171 | 1537-0437 | 29 | 2 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | 2020 | 1.178 | 65.9 | 2.49 | 2025-06-25 | 20 | 22 | Salmonella; multidrug resistance; integron; antimicrobial resistance gene; plasmid | ESCHERICHIA-COLI; BETA-LACTAMASES; SUPPLY CHAIN; ENTERICA; PREVALENCE; GENES; SEROVARS; PLASMID; CHLORAMPHENICOL; TYPHIMURIUM | antimicrobial resistance gene; integron; multidrug resistance; plasmid; Salmonella | English | 2020 | 2020-06 | 10.1016/j.japr.2019.12.010 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Molecular characterization of multidrug-resistant avian pathogenic Escherichia coli from broiler chickens in Korea | This study was conducted to determine the phenotypic and genotypic characteristics of multidrug-resistant (MDR) avian pathogenic Escherichia coli (APEC). A total of 54 MDR APEC were divided into 23 serotypes, and O78 (16.6%) was the most frequently observed. The MDR APEC carried beta-lactamase-encoding genes (38.9%), integrons (61.6%), plasmid-mediated quinolone-resistant genes (20.4%), tetracycline-resistant genes (79.6%), sulfonamide-resistant genes (40.7%), and chloramphenicol-resistant genes (18.5%). Phylogenetic group D (44.4%), which is associated with extraintestinal strains, was the most frequently observed, but all MDR APEC, including groups A, B1, and B2, carried one or more virulence genes. This study analyzed the phenotypic and genotypic characterization in MDR APEC isolated from broilers with colibacillosis in Korea. It is important to monitor the occurrence of resistance genes in APEC. These bacteria may pose serious therapeutic problems when treating sick broilers. The MDR strains carried by animals and birds can enter the human food chain through the consumption of meat or other animal or poultry products. | Kim, Y. B.; Yoon, M. Y.; Seo, K. W.; Yoon, S.; Lee, Y. J. | Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Zoonoses Res Inst, Daegu 41566, South Korea; Samhwa GPS Breeding Agri Inc, Qual Control Team, Hongseong 32291, South Korea; Mississippi State Univ, Coll Vet Med, Dept Basic Sci, Mississippi State, MS 39762 USA | ; Yoon, Sunghyun/AAL-4806-2021 | 57200044764; 57214463716; 57203233812; 57216037473; 56612134500 | youngju@knu.ac.kr; | JOURNAL OF APPLIED POULTRY RESEARCH | J APPL POULTRY RES | 1056-6171 | 1537-0437 | 29 | 4 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | 2020 | 1.178 | 65.9 | 0.16 | 2025-06-25 | 1 | 4 | Avian pathogenic Escherichia coli; Serotypes; Multidrug resistance; Virulence gene; phylogenetic group | ANTIMICROBIAL RESISTANCE; STRAINS; GENES; VIRULENCE | Avian pathogenic Escherichia coli; Multidrug resistance; phylogenetic group; Serotypes; Virulence gene | English | 2020 | 2020-12 | 10.1016/j.japr.2020.09.014 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | On the Individuals Chart with Supplementary Runs Rules under Serial Dependence | To improve the sensitivity of a Shewhart control chart, it is common among practitioners to use supplementary runs rules. The performance of such runs rules charts is studied in the presence of positive autocorrelation caused by a first-order discrete autoregressive process. This type of data-generating process allows to compute the chart's run length properties exactly and efficiently, by utilizing the finite Markov chain embedding technique. Explicit formulae are derived for common types of runs rules. Afterwards, a detailed performance study about runs rules charts under serial dependence is presented. | Oh, Jungtaek; Weiss, Christian H. | Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Changwon Natl Univ, Res Inst Basic Sci, Chang Won, South Korea; Helmut Schmidt Univ, Dept Math & Stat, Hamburg, Germany | Oh, Jungtaek/GWP-5136-2022 | 57788549600; 7202167195 | mathguide@nate.com;weissc@hsu-hh.de; | METHODOLOGY AND COMPUTING IN APPLIED PROBABILITY | METHODOL COMPUT APPL | 1387-5841 | 1573-7713 | 22 | 3 | SCIE | STATISTICS & PROBABILITY | 2020 | 1.147 | 66.0 | 1.67 | 2025-06-25 | 8 | 10 | Shewhart control chart; Sensitizing runs rules; Autocorrelation; Finite Markov chain embedding; Run length performance | SHEWHART CONTROL CHARTS; MARKOV-CHAIN; LENGTH DISTRIBUTION; SCHEMES | Autocorrelation; Finite Markov chain embedding; Run length performance; Sensitizing runs rules; Shewhart control chart | English | 2020 | 2020-09 | 10.1007/s11009-019-09760-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A Subnormal Completion Problem for Weighted Shifts on Directed Trees, II | The subnormal completion problem on a directed tree is to determine, given a collection of weights on a subtree, whether the weights may be completed to the weights of a subnormal weighted shift on the directed tree. We study this problem on a directed tree with a single branching point, eta branches and the trunk of length 1 and its subtree which is the "truncation" of the full tree to vertices of generation not exceeding 2. We provide necessary and sufficient conditions written in terms of two parameter sequences for the existence of a subnormal completion in which the resulting measures are 2-atomic. As a consequence, we obtain a solution of the subnormal completion problem for this pair of directed trees when eta= 120). Thirty-nine patients with sleep disturbance who agreed to take LCE at bedtime completed 3-month follow-ups. We analyzed changes in the scores of motor, nonmotor, and sleep symptom scales over the 3 months. Results PD patients with sleep disturbance were at more advanced disease stages and had more severe motor, nonmotor, and sleep symptoms than those without sleep disturbance. Patients who took LCE at night showed improvements in motor (UPDRS part III, p = 0.007) and sleep symptoms (total PDSS, p < 0.001). Sleep features that benefitted from LCE included not only nocturnal motor components but also insomnia (PDSS items 2 and 3, p = 0.005 and p < 0.001) and rapid eye movement behavior disorder (PDSS item 6, p = 0.002; and RBDSQ, p < 0.001). Conclusion The use of LCE at bedtime may be a useful treatment for sleep disturbance in advanced PD patients with motor fluctuations. | Exner, George R.; Jung, Il Bong; Stochel, Jan; Yun, Hye Yeong | Univ Ulsan, Asan Med Ctr, Coll Med, Dept Neurol, 88 Olympio Ro 43 Gil, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Neurol, Daegu, South Korea | 57194448346; 57204969008; 57219164267; 57219161130; 57748908700; 57014206500; 56882955600 | sjchung@amo.seoul.kr;sjchung@amc.seoul.kr; | INTEGRAL EQUATIONS AND OPERATOR THEORY | J MOV DISORD | 2005-940X | 2093-4939 | 13 | 3 | SCIE | CLINICAL NEUROLOGY | 2020 | 2.683 | 66.1 | 0.81 | 2025-06-25 | 14 | 16 | Subnormal operator; Weighted shift on a directed tree; Subnormal completion problem; 2-Atomic measures | ALevodopa; Parkinson’s disease; Sleep wake disorders | English | 2020 | 2020-09 | 10.14802/jmd.20055 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Letter | Combined Hemichorea and Seizures in a Patient with Nonketotic Hyperglycemia | Kim, Ryul; Cho, Hee-Jin; Lee, Ho-Won; Jun, Jin-Sun | Seoul Natl Univ Hosp, Dept Neurol, Seoul, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurol, Daegu, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu, South Korea; Hallym Univ, Kangnam Sacred Heart Hosp, Coll Med, Dept Neurol, 1 Singil Ro, Seoul 07441, South Korea | 56591470700; 55937716400; 35337240700; 56523978900 | junjinsun0401@gmail.com; | JOURNAL OF MOVEMENT DISORDERS | J MOV DISORD | 2005-940X | 2093-4939 | 13 | 1 | SCIE | CLINICAL NEUROLOGY | 2020 | 2.683 | 66.1 | 0.79 | 2025-06-25 | 5 | 7 | CHOREA | English | 2020 | 2020-01 | 10.14802/jmd.19058 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Amine-functionalized graphene oxide/zinc hexacyanoferrate composites for cesium removal from aqueous solutions | Amine-functionalized graphene oxide/zinc hexacyanoferrate (amino-rGO/ZnHCF) composites were successfully synthesized for the removal of Cs+ from radioactive liquid waste. Their morphologies, surface areas, pore sizes, functional groups, and thermal stabilities were investigated by field-emission transmission electron microscopy, Brunauer-Emmett-Teller analysis, Fourier transform infrared spectroscopy, and thermogravimetry. Adsorption experiments revealed high adsorption capacities at pH 5-7 and stability below pH 9. The dependence of the synthesized composites on the pseudo-second-order model and the Temkin model was also observed. The results of this study indicate that the new amino-rGO/ZnHCF composites are good adsorbent candidates for Cs removal from aqueous solutions. | Choi, Jung-Weon; Park, Yoon-Ji; Lee, Hyun-Kyu; Choi, Sang-June | Kyungpook Natl Univ, Sch Architectural Civil Environm & Energy Engn, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Adv Energy Technol, 80 Daehak Ro, Daegu 41566, South Korea | 56996378900; 57209361847; 36465457300; 56605563600 | sjchoi@knu.ac.kr; | JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | J RADIOANAL NUCL CH | 0236-5731 | 1588-2780 | 323 | 2 | SCIE | CHEMISTRY, ANALYTICAL;CHEMISTRY, INORGANIC & NUCLEAR;NUCLEAR SCIENCE & TECHNOLOGY | 2020 | 1.371 | 66.2 | 0.16 | 2025-06-25 | 4 | 3 | Adsorption; Cesium; Zinc hexacyanoferrate; Adsorbent; Radionuclide; Radioactive liquid waste; Graphene oxide | SELECTIVE REMOVAL; COPPER HEXACYANOFERRATE; AGRICULTURAL RESIDUE; HALF-LIFE; SORPTION; NICKEL; NANOCOMPOSITE; ADSORPTION; WASTE; DECONTAMINATION | Adsorbent; Adsorption; Cesium; Graphene oxide; Radioactive liquid waste; Radionuclide; Zinc hexacyanoferrate | adsorbent; amine; cesium; functional group; graphene oxide; unclassified drug; zinc derivative; zinc hexacyanoferrate; adsorption; aqueous solution; Article; Brunauer Emmett Teller analysis; chemical parameters; chemical structure; controlled study; Fourier transform infrared spectroscopy; liquid waste; mathematical model; molecular stability; pH; pore size; pseudo second order model; radioactive waste; surface area; synthesis; Temkin model; thermogravimetry; thermostability; transmission electron microscopy | English | 2020 | 2020-02 | 10.1007/s10967-019-07002-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Increased risk of malignancy in patients aged over 50 with idiopathic inflammatory myositis compared to patients with osteoarthritis of the knee | Objectives: To estimate risk of malignancy in patients with idiopathic inflammatory myositis (IIM) compared to patients with knee osteoarthritis (OA). Methods: Patients with IIM and knee OA aged over 50, who had no history of malignancy, were identified using Korean National claims database from January 2012 to December 2014. They had been observed until a malignancy was diagnosed or up to the end of the study, December 2015. The incidence rate (IR) of malignancy in IIM patients was calculated and compared with knee OA patients using standardized incidence ratio (SIR). Results: A total of 634 polymyositis (PM) and 556 dermatomyositis (DM) patients were included. Overall, 100 solid (IR 270.4/10,000 person-years (PY), 95% confidence interval (CI) 217.4-323.4) and 12 hematologic malignancies (IR 32.4/10,000 PY, 95% CI 14.1-50.8) occurred. Compared with knee OA, risk of overall (SIR 1.5, 95% CI 1.2-1.8), solid (SIR 1.4, 95% CI 1.1-1.6), and hematologic malignancy (SIR 5.7, 95% CI 2.5-9.0) were increased in IIM patients. This was due to increased incidence of malignancy in DM (hematologic malignancy, SIR 8.7, 95% CI 2.7-14.7, solid malignancy, SIR 1.5, 95% CI 1.1-1.9). Conclusion: Patients with IIM, especially DM, have an increased risk of malignancy compared to patients with knee OA. | Kim, Hyoungyoung; Sung, Yoon-Kyoung; Choi, Seongmi; Im, Seul Gi; Jung, Sun-Young; Jang, Eun Jin; Yoo, Dae Hyun; Cho, Soo-Kyung | Hanyang Univ, Dept Rheumatol, Hosp Rheumat Dis, Seoul 04763, South Korea; Natl Hlth Insurance Serv, Hlth Insurance Policy Res Inst, Wonju, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Chung Ang Univ, Coll Pharm, Seoul, South Korea; Andong Natl Univ, Dept Informat Stat, Andong, South Korea | Yoo, Dae/M-3924-2017 | 57202108695; 15754508900; 57211676692; 57201022006; 57207445502; 37861741600; 34668711700; 35185890800 | skchomd@hanyang.ac.kr; | MODERN RHEUMATOLOGY | MOD RHEUMATOL | 1439-7595 | 1439-7609 | 30 | 5 | SCIE | RHEUMATOLOGY | 2020 | 3.023 | 66.2 | 0 | 2025-06-25 | 5 | 0 | Neoplasm; myositis; dermatomyositis; polymyositis | CANCER-RISK; NASOPHARYNGEAL CARCINOMA; PREDICTIVE FACTORS; INCIDENCE RATES; DERMATOMYOSITIS; POLYMYOSITIS; ASSOCIATION; MORTALITY; COHORT; MYOPATHIES | dermatomyositis; myositis; Neoplasm; polymyositis | Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Myositis; Neoplasms; Osteoarthritis, Knee; adult; Article; colorectal cancer; controlled study; dermatomyositis; female; health care system; health insurance; hematologic malignancy; human; ICD-10; idiopathic inflammatory myositis; knee osteoarthritis; larynx cancer; lip cancer; liver cancer; lung cancer; lymphoma; major clinical study; male; middle aged; morbidity; myositis; nonhodgkin lymphoma; oropharynx carcinoma; polymyositis; prevalence; prostate cancer; risk; standardized incidence ratio; thyroid cancer; age; aged; complication; knee osteoarthritis; myositis; neoplasm | English | 2020 | 2020-09-02 | 10.1080/14397595.2019.1660041 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Measurement of ⁿatNi(γ, xn)⁵⁷,⁵⁶Ni and ⁿatNi(γ, pxn)⁵⁸⁻⁵⁵Co reaction cross sections in bremsstrahlung with end-point energies of 65 and 75 MeV | The cross sections of Ni-nat(gamma, xn)Ni-57,Ni-56 and Ni-nat(gamma, pxn)Co58-55 reactions induced by bremsstrahlung end-point energies of 65 and 75 MeV were measured by using the method of activation along with off-line gamma-ray spectrometric technique. The Ni-nat(gamma, xn)Ni-57,Ni-56 and Ni-nat(gamma, pxn)Co58-55 reaction cross sections as a function of photon energy were also calculated by using TALYS 1.9 code. The flux-weighted average values at different end-point energies were obtained from the literature data, as well as from the theoretical values of TALYS and TENDL-2017 data library based on mono-energetic photons. Those were compared with the experimental data of present work and found to be in general agreement. It was also found that the experimental and theoretical cross-sections data increase with bremsstrahlung energy up to a certain value. After that the individual reaction cross sections slightly decrease with the increase of bremsstrahlung energy due to the opening of other reactions. As an example, the Ni-nat(gamma, xn)Ni-57 reaction cross section decreases when the Ni-nat(gamma, xn)Ni-56 reaction opens up. Similarly, the Ni-nat(gamma, pxn)Co-58 reaction cross section decreases when Ni-nat(gamma, pxn)Co-57 reaction opens up and so on. These observations indicate the role of excitation energy and its portion in different reaction channels. | Naik, Haladhara; Kim, Guinyun; Nguyen, Thi Hien; Kim, Kwangsoo; Shin, Sung-Gyun; Kye, Yong-uk; Cho, Moo-Hyun | Bhabha Atom Res Ctr, Radiochem Div, Mumbai 400085, Maharashtra, India; Kyungpook Natl Univ, Dept Phys, Daegu 702701, South Korea; Pohang Univ Sci & Technol, Div Adv Nucl Engn, Pohang 790784, South Korea | Nguyen, Thong/ABV-0605-2022 | 7005890232; 35313854400; 57201066391; 36137214700; 55770867100; 56020858600; 17136702900 | gnkim@knu.ac.kr; | JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | J RADIOANAL NUCL CH | 0236-5731 | 1588-2780 | 324 | 2 | SCIE | CHEMISTRY, ANALYTICAL;CHEMISTRY, INORGANIC & NUCLEAR;NUCLEAR SCIENCE & TECHNOLOGY | 2020 | 1.371 | 66.2 | 0.16 | 2025-06-25 | 4 | 4 | Cross section; Ni-nat(gamma xn)Ni-57,Ni-56 reactions; Ni-nat(gamma pxn)Co58-55 reactions; Al-27(gamma 2pn)Na-24 monitor reaction; Bremsstrahlung end-point energies of 65 and 75 MeV; Activation along with off-line gamma-ray spectrometric technique; TALYS 1; 9 calculation | NUCLEAR-DATA; REACTORS; SYSTEMS | <sup>27</sup>Al(γ2pn)<sup>24</sup>Na monitor reaction; <sup>nat</sup>Ni(γpxn)<sup>58−55</sup>Co reactions; <sup>nat</sup>Ni(γxn)<sup>57,56</sup>Ni reactions; Activation along with off-line γ-ray spectrometric technique; Bremsstrahlung end-point energies of 65 and 75 MeV; Cross section; TALYS 1.9 calculation | cobalt 55; cobalt 56; cobalt 57; cobalt 58; isotope; nickel 56; nickel 57; unclassified drug; 65 bremsstrahlung end point energy; 75 bremsstrahlung end point energy; Article; electron beam; gamma radiation; gamma spectrometry; irradiation; photon; radiation detection; radiation measurement; radioisotope decay; radiological parameters; reaction analysis | English | 2020 | 2020-05 | 10.1007/s10967-020-07105-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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