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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Endophytic Fungi of Salt-Tolerant Plants: Diversity and Ability to Promote Plant Growth Suaeda australis, Phragmites australis, Suaeda maritima, Suaeda glauca Bunge, and Limonium tetragonum in the Seocheon salt marsh on the west coast of the Korean Penincula were sampled in order to identify the endophytes inhabiting the roots. A total of 128 endophytic fungal isolates belonging to 31 different genera were identified using the fungal internal transcribed spacer (ITS) regions and the 5.8S ribosomal RNA gene. Fusarium, Paraconiothyrium and Alternaria were the most commonly isolated genera in the plant root samples. Various diversity indicators were used to assess the diversity of the isolated fungi. Pure cultures containing each of the 128 endophytic fungi, respectively, were tested for the plant growth-promoting abilities of the fungus on Waito-C rice germinals. The culture filtrate of the isolate Lt-1-3-3 significantly increased the growth of shoots compared to the shoots treated with the control. Lt-1-3-3 culture filtrate was analyzed and showed the presence of gibberellins (GA1 2.487 ng/ml, GA3 2.592 ng/ml, GA9 3.998, and GA24 6.191 ng/ml). The culture filtrate from the Lt-1-3-3 fungal isolate produced greater amounts of GA9 and GA24 than the wild-type Gibberella fujikuroi, a fungus known to produce large amounts of gibberellins. By the molecular analysis, fungal isolate Lt-1-3-3 was identified as Gibberella intermedia, with 100% similarity. Khalmuratova, Irina; Choi, Doo-Ho; Kim, Jong-Guk; Lee, In-Seon Kyungpook Natl Univ, Sch Life Sci & Biotechnol, Daegu 41566, South Korea; Keimyung Univ, Dept Food Sci & Technol, Daegu 42601, South Korea 55908352900; 57211275161; 35277198800; 15832174200 inseon@kmu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 11 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0.93 2025-07-30 13 13 Coastal plants; fungal diversity; fungal endophytes; plant growth-promoting activity; gibberellin HOST; ACID Coastal plants; Fungal diversity; Fungal endophytes; Gibberellin; Plant growth-promoting activity Alternaria; Ascomycota; DNA, Fungal; DNA, Ribosomal Spacer; Endophytes; Fusarium; Gibberellins; Oryza; Plant Development; Plant Roots; Republic of Korea; RNA, Ribosomal, 5.8S; Salt-Tolerant Plants; Wetlands; gibberellin; fungal DNA; ribosomal spacer DNA; RNA 5.8S; Alternaria; Article; coastal waters; controlled study; endophytic fungus; Fusarium; halophyte; Limonium tetragonum; microbial diversity; nonhuman; Paraconiothyrium; Phragmites australis; plant growth; Suaeda australis; Suaeda glauca bunge; Suaeda maritima; Ascomycetes; classification; endophyte; genetics; growth, development and aging; halophyte; isolation and purification; microbiology; Oryza; plant development; plant root; South Korea; wetland English 2021 2021-11 10.4014/jmb.2106.06007 바로가기 바로가기 바로가기 바로가기
Article Functions of PUF Family RNA-Binding Proteins in Aspergillus nidulans RNA-binding proteins are involved in RNA metabolism and posttranscriptional regulation of various fundamental biological processes. The PUF family of RNA-binding proteins is highly conserved in eukaryotes, and its members regulate gene expression, mitochondrial biogenesis, and RNA processing. However, their biological functions in Aspergillus species remain mostly unknown in filamentous fungi. Here we have characterized the puf genes in the model organism Aspergillus nidulans. We generated deletion mutant strains for the five putative puf genes present in the A. nidulans genome and investigated their developmental phenotypes. Deletion of pufA or pufE affected fungal growth and asexual development. pufA mutants exhibited decreased production of asexual spores and reduced mRNA expression of genes regulating asexual development. The pufE deletion reduced colony growth, increased formation of asexual spores, and delayed production of sexual fruiting bodies. In addition, the absence of pufE reduced both sterigmatocystin production and the mRNA levels of genes in the sterigmatocystin cluster. Finally, pufE deletion mutants showed reduced trehalose production and lower resistance to thermal stress. Overall, these results demonstrate that PufA and PufE play roles in the development and sterigmatocystin metabolism in A. nidulans. Son, Sung-Hun; Jang, Seo-Yeong; Park, Hee-Soo Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Integrat Biol, Daegu 41566, South Korea Park, Hee-Soo/AAC-6422-2019 57214091244; 57224108380; 15751448400 phsoo97@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 5 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0.34 2025-07-30 4 4 PUF domain; RNA-binding protein; asexual development; sterigmatocystin; conidia ASEXUAL SPORULATION; SEXUAL DEVELOPMENT; TRANSCRIPTS; ENCODES; CLUSTER; DESIGN; AFLR asexual development; conidia; PUF domain; RNA-binding protein; sterigmatocystin Aspergillus nidulans; Fungal Proteins; Gene Expression Regulation, Fungal; Mutation; Protein Domains; RNA, Messenger; RNA-Binding Proteins; Spores, Fungal; Sterigmatocystin; Thermotolerance; Trehalose; fungal RNA; messenger RNA; Pumilio Fem 3 binding factor protein; RNA binding protein; sterigmatocystin; trehalose; unclassified drug; fungal protein; messenger RNA; RNA binding protein; sterigmatocystin; trehalose; Article; asexual spore; Aspergillus nidulans; controlled study; fruiting body; fungal development; fungal gene; fungal genome; fungus growth; fungus mutant; gene deletion; gene expression; gene expression level; nonhuman; phenotype; protein function; pufA gene; pufE gene; temperature stress; Aspergillus nidulans; biosynthesis; fungus spore; gene expression regulation; genetics; growth, development and aging; heat tolerance; metabolism; mutation; protein domain English 2021 2021-05 10.4014/jmb.2101.01011 바로가기 바로가기 바로가기 바로가기
Article Periplanetasin-2 Enhances the Antibacterial Properties of Vancomycin or Chloramphenicol in Escherichia coli Periplanetasin-2 from cockroach exhibits broad-spectrum antimicrobial activity. The underlying antibacterial mechanisms rely on the stimulation of reactive oxygen species overproduction to induce apoptotic cell death. A promising strategy to increase the bioavailability of periplanetasin-2 involves reducing the dose through combination therapy with other antibacterials that show synergistic effects. Thus, the synergistic antibacterial activity of periplanetasin-2 with conventional antibacterial agents and its mechanisms was examined against Escherichia coli in this study. Among the agents tested, the combinations of periplanetasin-2 with vancomycin and chloramphenicol exhibited synergistic effects. Periplanetasin-2 in combination with vancomycin and chloramphenicol demonstrated antibacterial activity through the intracellular oxidative stress response. The combination with vancomycin resulted in the enhancement of bacterial apoptosislike death, whereas the combination with chloramphenicol enhanced oxidative stress damage. These synergistic interactions of periplanetasin-2 can help broaden the spectrum of conventional antibiotics. The combination of antimicrobial peptides and conventional antibiotics is proposed as a novel perspective on treatments to combat severe bacterial infection. Lee, Heejeong; Hwang, Jae Sam; Lee, Dong Gun Kyungpook Natl Univ, Sch Life Sci, BK21 Four KNU Creat BioRes Grp, Daegu 41566, South Korea; Natl Acad Agr Sci, Dept Agr Biol, RDA, Wonju 55365, South Korea Lee, Dong-Gun/IWD-9833-2023 56010549700; 16637012100; 55668060900 dglee222@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 2 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0.51 2025-07-30 6 6 Periplanetasin-2; vancomycin; chloramphenicol; synergistic interaction ANTIMICROBIAL PEPTIDE; SILVER NANOPARTICLES; COMBINATION THERAPY; DNA-DAMAGE; ANTIBIOTICS; MECHANISMS; DEATH Chloramphenicol; Periplanetasin-2; Synergistic interaction; Vancomycin Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Chloramphenicol; Drug Synergism; Escherichia coli; Microbial Sensitivity Tests; Oxidative Stress; Vancomycin; amikacin; antiinfective agent; bacterial protein; calcium; caspase; cefotaxime; chloramphenicol; ciprofloxacin; kanamycin; lipid; norfloxacin; periplanetasin 2; polypeptide antibiotic agent; reactive oxygen metabolite; rifampicin; unclassified drug; vancomycin; antiinfective agent; antimicrobial cationic peptide; chloramphenicol; vancomycin; antibacterial activity; antimicrobial activity; apoptosis; Article; bacterial infection; bacterial strain; bacterium culture; calcium cell level; cell death; controlled study; disease severity; drug bioavailability; drug mechanism; enzyme activation; Escherichia coli infection; flow cytometry; lipid peroxidation; minimum inhibitory concentration; nonhuman; oxidative stress; synergistic effect; drug effect; drug potentiation; Escherichia coli; growth, development and aging; metabolism; microbial sensitivity test English 2021 2021-02 10.4014/jmb.2010.10058 바로가기 바로가기 바로가기 바로가기
Article Production of Algal Biomass and High-Value Compounds Mediated by Interaction of Microalgal Oocystis sp. KNUA044 and Bacterium Sphingomonas KNU100 There is growing interest in the production of microalgae-based, high-value by-products as an emerging green biotechnology. However, a cultivation platform for Oocystis sp. has yet to be established. We therefore examined the effects of bacterial culture additions on the growth and production of valuable compounds of the microalgal strain Oocystis sp. KNUA044, isolated from a locally adapted region in Korea. The strain grew only in the presence of a clear supernatant of Sphingomonas sp. KNU100 culture solution and generated 28.57 mg/ l/d of biomass productivity. Protein content (43.9 wt%) was approximately two- fold higher than carbohydrate content (29.4 wt%) and lipid content (13.9 wt%). Oocystis sp. KNUA044 produced the monosaccharide fucose (33 mu g/mg and 0.94 mg/l/d), reported here for the first time. Fatty acid profiling showed high accumulation (over 60%) of polyunsaturated fatty acids (PUFAs) compared to saturated (29.4%) and monounsaturated fatty acids (9.9%) under the same culture conditions. Of these PUFAs, the algal strain produced the highest concentration of linolenic acid (C18: 3.3; 40.2%) in the omega-3 family and generated eicosapentaenoic acid (C20:5.3; 6.0%), also known as EPA. Based on these results, we suggest that the application of Sphingomonas sp. KNU100 for strain-dependent cultivation of Oocystis sp. KNUA044 holds future promise as a bioprocess capable of increasing algal biomass and high-value bioactive by- products, including fucose and PUFAs such as linolenic acid and EPA. Na, Ho; Jo, Seung-Woo; Do, Jeong-Mi; Kim, Il-Sup; Yoon, Ho-Sung Kyungpook Natl Univ, Dept Biol, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Life Sci, BK21 Plus KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Adv Bioresource Res Ctr, Daegu 41566, South Korea 57211975842; 56018962600; 57208562245; 55477678200; 7402990205 92kis@hanmail.net;hsy@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 3 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0.51 2025-07-30 10 11 Oocystis spp.; Sphingomonas spp.; symbiotic interaction; algal biomass; eicosapentaenoic acid; fucose POLYUNSATURATED FATTY-ACIDS; SULFATED POLYSACCHARIDES; BIOCHEMICAL-CHARACTERIZATION; EICOSAPENTAENOIC ACID; GREEN MICROALGA; CULTIVATION; LIPIDS; WATER; TEMPERATURE; STRAINS Algal biomass; Eicosapentaenoic acid; Fucose; Oocystis spp.; Sphingomonas spp.; Symbiotic interaction Biofuels; Biomass; Carbohydrate Metabolism; Culture Media; Eicosapentaenoic Acid; Fatty Acids; Fucose; Industrial Microbiology; Lipids; Microalgae; Microbial Interactions; Protein Biosynthesis; Republic of Korea; Sphingomonas; Symbiosis; biodiesel; fucose; icosapentaenoic acid; linolenic acid; monounsaturated fatty acid; omega 3 fatty acid; polyunsaturated fatty acid; saturated fatty acid; biofuel; fatty acid; fucose; icosapentaenoic acid; icosapentaenoic acid ethyl ester; lipid; algal growth; Article; bacterium culture; bacterium identification; biomass production; carbohydrate analysis; controlled study; lipid composition; lipid storage; microalga; microbial interaction; nonhuman; Oocystis; Oocystis heteromucosa; protein content; South Korea; Sphingomonas; biomass; biosynthesis; carbohydrate metabolism; culture medium; growth, development and aging; metabolism; microalga; microbiology; organismal interaction; procedures; protein synthesis; Sphingomonas; symbiosis English 2021 2021-03 10.4014/jmb.2009.09055 바로가기 바로가기 바로가기 바로가기
Article Pyrosequencing and Taxonomic Composition of the Fungal Community from Soil of Tricholoma matsutake in Gyeongju Tricholoma matsutake is an ectomycorrhizal fungus that has a symbiotic relationship with the root of Pinus densiflora. Soil microbial communities greatly affect the growth of T. matsutake, however, few studies have examined the characteristics of these communities. In the present study, we analyzed soil fungal communities from Gyeongju and Yeongdeok using metagenomic pyrosequencing to investigate differences in fungal species diversity, richness, and taxonomic composition between the soil under T. matsutake fruiting bodies (Sample 2) and soil where the fairy ring of T. matsutake was no longer present (Sample 1). The same spot was investigated three times at intervals of four months to observe changes in the community. In the samples from Yeongdeok, the number of valid reads was lower than that at Gyeongju. The operational taxonomic units of most Sample 2 groups were less than those of Sample 1 groups, indicating that fungal diversity was low in the T. matsutake- dominant soil. The soil under the T. matsutake fruiting bodies was dominated by more than 51% T. matsutake. From fall to the following spring, the ratio of T. matsutake decreased. Basidiomycota was the dominant phylum in most samples. G-F1-2, G-F2-2, and Y-F1-2 had the genera Tricholoma, Umbelopsis, Oidiodendron, Sagenomella, Cladophialophora, and Phialocephala in common. G-F1-1, G-F2-1, and Y-F1-1 had 10 genera including Umbelopsis and Sagenomella in common. From fall to the following spring, the amount of phyla Basidiomycota and Mucoromycota gradually decreased but that of phylum Ascomycota increased. We suggest that the genus Umbelopsis is positively related to T. matsutake. Jeong, Minji; Choi, Doo-Ho; Cheon, Woo-Jae; Kim, Jong-Guk Kyungpook Natl Univ, Dept Life Sci & Biotechnol, Daegu 41566, South Korea; Gyeongsangbuk Do Forest Environm Res Inst, Dept Forest Environm, Gyeong Ju 38174, South Korea 57205877584; 57211275161; 57189041656; 35277198800 kimjg@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 5 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0.34 2025-07-30 3 4 Fungal community; Tricholoma matsutake; metagenomics MICROBIAL COMMUNITIES; ECTOMYCORRHIZAL FUNGI; BACTERIAL DIVERSITY; FAIRY RING; FOREST; PLANT; METAGENOMICS; MYCELIUM; PROTEIN; TREES Fungal community; metagenomics; Tricholoma matsutake Agaricales; Fungi; High-Throughput Nucleotide Sequencing; Metagenomics; Mycobiome; Pinus; Republic of Korea; Seasons; Soil Microbiology; article; Cladophialophora; fruiting body; fungal community; metagenomics; nonhuman; phylum; pyrosequencing; soil; species diversity; spring; Tricholoma matsutake; Umbelopsis; Agaricales; classification; fungus; genetics; growth, development and aging; high throughput sequencing; isolation and purification; metagenomics; microbiology; mycobiome; physiology; pine; season; South Korea English 2021 2021-05 10.4014/jmb.2103.03021 바로가기 바로가기 바로가기 바로가기
Article Safety Evaluation of Bifidobacterium breve IDCC4401 Isolated from Infant Feces for Use as a Commercial Probiotic Previously, our research group isolated Bifidobacterium breve IDCC4401 from infant feces as a potential probiotic. For this study, we evaluated the safety of B. breve IDCC4401 using genomic and phenotypic analyses. Whole genome sequencing was performed to identify genomic characteristics and investigate the potential presence of genes encoding virulence, antibiotic resistance, and mobile genetic elements. Phenotypic analyses including antibiotic susceptibility, enzyme activity, production of biogenic amines (BAs), and proportion of D-/L-lactate were evaluated using E-test, API ZYM test, high-performance liquid chromatography (HPLC), and D-/L-lactic acid assay respectively. The genome of B. breve IDCC4401 consists of 2,426,499 bp with a GC content of 58.70% and 2,016 coding regions. Confirmation of the genome as B. breve was provided by its 98.93% similarity with B. breve DSM20213. Furthermore,B. breve IDCC4401 genes encoding virulence and antibiotic resistance were not identified. Although B. breve IDCC4401 showed antibiotic resistance against vancomycin, we confirmed that this was an intrinsic feature since the antibiotic resistance gene was not present. B. breve IDCC4401 showed leucine arylamidase, cystine arylamidase, alpha-galactosidase, beta-galactosidase, and alpha-glucosidase activities, whereas it did not show production of harmful enzymes such as beta-glucosidase and beta-glucuronidase. In addition, B. breve IDCC4401 did not produce any tyramine, histamine, putrescine, cadaverine, or 2-phenethylamine, which are frequently detected BAs during fermentation. B. breve IDCC4401 produced 95.08% of L-lactate and 4.92% of D-lactate. Therefore, our findings demonstrate the safety of B. breve IDCC 4401 as a potential probiotic for use in the food industry. Choi, In Young; Kim, Jinhee; Kim, Su-Hyeon; Ban, O-Hyun; Yang, Jungwoo; Park, Mi-Kyung Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Food & Bioind Res Inst, Daegu 41566, South Korea; Korea Res Inst Chem Technol, Drug Informat Platform Ctr, Daejeon 41566, South Korea; Ildong BioSci, Pyeongtaek 17957, South Korea Park, Mi-Kyung/J-9643-2017 57200112496; 57216273873; 57217051011; 57219226382; 56076383700; 7404491155 parkmik@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 7 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 1.27 2025-07-30 17 16 Safety evaluation; probiotics; Bifidobacterium breve LACTIC-ACID BACTERIA; BIOGENIC-AMINES; STRAINS Bifidobacterium breve; Probiotics; Safety evaluation Anti-Bacterial Agents; Bacterial Proteins; Bifidobacterium breve; Drug Resistance, Bacterial; Feces; Food Safety; Genes, Bacterial; Genome, Bacterial; Humans; Infant; Lactic Acid; Microbial Sensitivity Tests; Probiotics; Vancomycin; alpha galactosidase; alpha glucosidase; ampicillin; aryl acylamidase; beta galactosidase; beta glucuronidase; biogenic amine; chloramphenicol; clindamycin; cystine arylamidase; erythromycin; gentamicin; kanamycin; lactic acid; leucine arylamidase; probiotic agent; streptomycin; tetracycline; unclassified drug; vancomycin; antiinfective agent; bacterial protein; lactic acid; vancomycin; antibiotic resistance; antibiotic sensitivity; Article; assay; bacterial gene; bacterial genome; bacterial virulence; Bifidobacterium breve; controlled study; DNA base composition; enzyme activity; epsilometer test; fermentation; genomics; high performance liquid chromatography; human; ifidobacterium breve IDCC4401; infant; lactic acid assay; minimum inhibitory concentration; mobile genetic element; whole genome sequencing; Bifidobacterium breve; drug effect; feces; food safety; genetics; isolation and purification; metabolism; microbial sensitivity test; microbiology English 2021 2021-07 10.4014/jmb.2103.03041 바로가기 바로가기 바로가기 바로가기
Article Helicoidal surfaces with prescribed curvatures in a conformally flat 3-space In this paper, we study a conformally flat 3-space. F-3 which is an Euclidean 3-space with a conformally flat metric with the conformal factor 1/F-2, where F(x) = e(-x12-x22) for x = (x(1), x(2), x(3)) is an element of R-3. In particular, we construct all helicoidal surfaces in F-3 by solving the second-order non-linear ODE with extrinsic curvature and mean curvature functions. As a result, we give classification of minimal helicoidal surfaces as well as examples for helicoidal surfaces with some extrinsic curvature and mean curvature functions in F-3. Lee, Chul Woo; Lee, Jae Won; Yoon, Dae Won Gyeongsang Natl Univ, Dept Math Educ, Jinju 52828, South Korea; Gyeongsang Natl Univ, RINS, Jinju 52828, South Korea; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea 7202875768; 56100882300; 55917980500 mathisu@knu.ac.kr;leejaew@gnu.ac.kr;dwyoon@gnu.ac.kr; GEORGIAN MATHEMATICAL JOURNAL GEORGIAN MATH J 1072-947X 1572-9176 28 5 SCIE MATHEMATICS 2021 0.9 55.1 0.22 2025-07-30 2 1 Conformally flat space; helicoidal surface; extrinsic curvature; mean curvature Conformally flat space; extrinsic curvature; helicoidal surface; mean curvature English 2021 2021-10 10.1515/gmj-2020-2087 바로가기 바로가기 바로가기 바로가기
Article Physicochemical, antioxidant, microstructural, and sensory characteristics of biscuits as affected by addition of onion residue Onion residue, obtained from onion processing, is valuable source of health-promoting compounds including polyphenols, mainly quercetin. In this study, biscuits were prepared by enrichment with onion residue (OS). Moreover, the influence of OS supplementation on physicochemical properties, antioxidant activities, mineral profiles, microstructural and sensory characteristics of biscuits were evaluated. Overall, the addition of OS up to 3% level significantly (p < 0.05) improved nutritional components, quercetin content, antioxidant activities and sensory scores of supplemented biscuits whereas further rises in OS caused sharply declining tendency in textural and sensorial properties. The environmental scanning electron microscopy (ESEM) results showed that OS hindered the structural formation of gluten network in biscuits and led to achieve loose biscuits. X-ray diffraction (XRD) revealed that addition of OS reduced the area of the crystallization zone. Biscuits added with OS up to 3% could be utilized as convenience foods and vehicle of improved nutritional status with health beneficial bioactive compounds. Moreover, supplementation of OS led to improvement of functional properties of biscuits as valuable source of bioactive compounds. Jiang, Guihun; Wu, Zhaogen; Ameer, Kashif; Song, Chunmei Jilin Med Univ, Sch Publ Hlth, 5 Jilin St, Jilin 132013, Jilin, Peoples R China; Chonnam Natl Univ, Integrat Food Biosci & Biotechnol, Gwangju 61186, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea Jiang, Guihun/KHU-2065-2024; Ameer, Kashif/H-5449-2019 57118696300; 57216727114; 57190066397; 57219310782 jiangguihun1@hotmail.com; JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION J FOOD MEAS CHARACT 2193-4126 2193-4134 15 1 SCIE FOOD SCIENCE & TECHNOLOGY 2021 3.006 55.2 0.84 2025-07-30 11 13 Biscuits; Onion residue; Physicochemical properties; Sensory characteristics WHEAT-FLOUR; QUALITY; DOUGH Biscuits; Onion residue; Physicochemical properties; Sensory characteristics Antioxidants; Flavonoids; Phenols; Physicochemical properties; Scanning electron microscopy; Anti-oxidant activities; Crystallization zone; Environmental scanning electron microscopies (ESEM); Functional properties; Health promoting compounds; Sensorial properties; Sensory characteristics; Structural formation; Bakeries English 2021 2021-02 10.1007/s11694-020-00681-0 바로가기 바로가기 바로가기 바로가기
Article The cumulative dose-dependent effects of metformin on the development of tuberculosis in patients newly diagnosed with type 2 diabetes mellitus Background Diabetes mellitus (DM) is a well-known risk factor for tuberculosis (TB). Metformin, which is an essential anti-diabetic drug, has been shown to exhibit anti-TB effects in patients with DM. Its effect on preventing the development of TB among patients who are newly diagnosed with DM remains unclear. Methods This was a retrospective cohort study using the claims database of the Korean Health Insurance Review and Assessment Service. The study population included patients who were newly diagnosed with type 2 DM and who were treated with anti-diabetic drugs between 1 January 2003 and 31 March 2011. A patient was defined as a metformin user if he/she had taken metformin for more than 28 days within 6 months since cohort entry, and as a metformin non-user if he/she had never been treated with metformin. The development of TB within 2 years after the index date was compared by Cox proportional hazard regression models between metformin users and 1:1 propensity score (PS)-matched non-users. Results Among 76,973 patients who were newly diagnosed with type 2 DM, 13,396 were classified as metformin users, 52,736 were classified as metformin non-users, and 10,841 were excluded from the final analysis. PS-matched Cox proportional hazard regression models revealed that metformin use was not associated overall with the prevention of TB development (HR 1.17; 95% CI 0.75-1.83; P = 0.482). There was a trend, however, towards a reduction in the development of TB among patients taking a higher cumulative dose of metformin. Patients who were in the highest quartile (Q4) of cumulative metformin dose had only a 10% risk of developing TB compared to metformin non-users. In contrast, during the early phases of metformin treatment, patients in the second quartile (Q2) of cumulative metformin use had a higher risk of developing TB than patients in the first quartile (Q1). Conclusions Only the highest cumulative doses of metformin were protective against the development of TB among patients who were newly diagnosed with type 2 DM; lower cumulative doses of metformin did not appear to reduce the incidence of active TB infection. Heo, Eunyoung; Kim, Eunyoung; Jang, Eun Jin; Lee, Chang-Hoon SNU SMG Boramae Med Ctr, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Andong Natl Univ, Dept Informat Stat, Andong, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Div Pulm & Crit Care Med, Seoul, South Korea Kim, Chang Gon/IAP-6721-2023; Lee, Hwan-Soo/AAO-7583-2021 55640179600; 59682525500; 37861741600; 56150043400 kauri670@empal.com; BMC PULMONARY MEDICINE BMC PULM MED 1471-2466 21 1 SCIE RESPIRATORY SYSTEM 2021 3.32 55.3 0.61 2025-07-30 9 9 Diabetes mellitus; Tuberculosis; Metformin; Prevention; Effect ACTIVATION; INFECTION; RISK; AMPK Diabetes mellitus; Effect; Metformin; Prevention; Tuberculosis Adult; Aged; Databases, Factual; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Propensity Score; Proportional Hazards Models; Republic of Korea; Retrospective Studies; Risk Factors; Tuberculosis; metformin; antidiabetic agent; metformin; adult; aged; Article; clinical evaluation; cohort analysis; data base; disease course; dose response; drug effect; female; high risk population; human; major clinical study; male; middle aged; non insulin dependent diabetes mellitus; retrospective study; risk factor; scoring system; trend study; tuberculosis; dose response; factual database; incidence; non insulin dependent diabetes mellitus; propensity score; proportional hazards model; South Korea; tuberculosis English 2021 2021-09-25 10.1186/s12890-021-01667-4 바로가기 바로가기 바로가기 바로가기
Article The Cross-Lagged Panel Analysis between Frailty and Physical Activity among Community-Dwelling Older Adults by Age Groups Objectives: This study was to investigate the reciprocal relationship between frailty and physical activity among older adults by age group (middle-old: 70-79 years; oldest-old: 80-84 years) within 2 years using cross-lagged panel analysis. Methods: The study data were derived from the Korean Frailty and Aging Cohort Study, and a total of 1092 participants were included. Results: Frailty and high physical activity had significant reciprocal relationships in the middle-old group, which indicates that frailty was associated with less high physical activity, and high physical activity predicts less frailty after 2 years. In the oldest-old group, there was no statistically significant reciprocal relationship between frailty and any level of physical activity reference to low physical activity and vice versa after 2 years. Discussion: Further studies on the relationship between frailty and physical activity of the oldest-old population and specific physical activity guidelines for older adults are needed. Sagong, Hae; Jang, Ah Ram; Kim, Da Eun; Won, Chang Won; Yoon, Ju Young Seoul Natl Univ, Coll Nursing, 103 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Coll Nursing, Ctr Human Caring Nurse Leaders, Future Brain Korea 21 Project 4, Seoul, South Korea; Kyungpook Natl Univ, Res Inst Nursing Sci, Coll Nursing, Daegu, South Korea; Kyung Hee Univ, Coll Med, Seoul, South Korea; Seoul Natl Univ, Res Inst Nursing Sci, Seoul, South Korea 57201527227; 57211535292; 57197746076; 56693973800; 55363051400 yoon26@snu.ac.kr; JOURNAL OF AGING AND HEALTH J AGING HEALTH 0898-2643 1552-6887 33 5-6 SSCI GERONTOLOGY;HEALTH POLICY & SERVICES 2021 2.609 55.4 1.27 2025-07-30 11 13 frailty; physical activity; longitudinal study; older adults EXERCISE; DEPRESSION; PREVALENCE; DISABILITY; DISEASE frailty; longitudinal study; older adults; physical activity Aged; Aged, 80 and over; Aging; Cohort Studies; Exercise; Frail Elderly; Frailty; Geriatric Assessment; Humans; Independent Living; aged; aging; cohort analysis; exercise; frail elderly; frailty; geriatric assessment; human; independent living; very elderly English 2021 2021-06 10.1177/0898264320987365 바로가기 바로가기 바로가기 바로가기
Article Enzymatic transformation products of phloretin as potent antiadipogenic compounds Enzymatic structure modification of the representative chalcone phloretin (1) with polyphenol oxidase from Agaricus bisporus origin produced 2 new biphenyl-type phloreoxin (2) and phloreoxinone (3), and a previously undescribed (2R)-5,7,3',5'-tetrahydroxyflavanone (4). The structure of these new oxidized products 2-4 elucidated by interpreting the spectroscopic data (NMR and FABMS) containing the absolute stereochemistry is established by the analysis of the circular dichroism spectrum. Compared to the original phloretin, the new products (2) and (3) showed highly improved antiadipogenic potencies both toward pancreatic lipase and accumulation of 3T3-L1 cells. Also, phloreoxin (2) effectively inhibited the expression of C/EBP beta, PPAR gamma, and aP2 at the mRNA level in the 3T3 adipocytes. Thus, phloreoxin (2), containing a biphenyl moiety catalyzed by A. bisporus polyphenol oxidase, have the potential to influence the antiadipogenic capacity. [GRAPHICS] Enzymatic oxidation products 2 and 3 of phloretin as potent antiadipogenic effects. Jeong, Gyeong Han; Cho, Jae-Hyeon; Park, Eui Kyun; Kim, Tae Hoon Daegu Univ, Dept Food Sci & Biotechnol, Gyongsan, South Korea; Gyeongsang Natl Univ, Coll Vet Med, Inst Anim Med, Jinju, South Korea; Kyungpook Natl Univ, Dept Pathol & Regenerat Med, Daegu, South Korea 57194900369; 14035176800; 37071072400; 56906394500 jaehcho@gnu.ac.kr;epark@knu.ac.kr;skyey7@daegu.ac.kr; BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY BIOSCI BIOTECH BIOCH 0916-8451 1347-6947 85 12 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY;BIOTECHNOLOGY & APPLIED MICROBIOLOGY;CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY 2021 2.337 55.5 0.23 2025-07-30 4 4 polyphenol oxidase; phloretin oxidation; biotransformation; pancreatic lipase; adipocyte differentiation POLYPHENOL OXIDASE; HORSERADISH-PEROXIDASE; THERMAL INACTIVATION; ALPHA-GLUCOSIDASE; LIPASE; INHIBITORS; BIOTRANSFORMATION; (+)-CATECHIN; PHLORHIZIN; FLAVONOIDS adipocyte differentiation; biotransformation; pancreatic lipase; phloretin oxidation; polyphenol oxidase Phloretin; Spectroscopic analysis; phloretin; Adipocyte differentiation; Agaricus bisporus; Chalcones; Enzymatic transformation; Pancreatic lipase; Phloretin; Phloretin oxidation; Polyphenol oxidase; Structure modification; Transformation products; Dichroism English 2021 2021-12 10.1093/bbb/zbab168 바로가기 바로가기 바로가기 바로가기
Article Magnetic ion-imprinted polymer based on mesoporous silica for selective removal of Co(II) from radioactive wastewater A magnetically separable Co(II)-imprinted polymer based on mesoporous silica (mag@silica-CIP) was synthesized for use as an adsorbent for the selective removal of Co(II). The optimal pH for Co(II) adsorption was found to be 5. Increasing the amount of the Co(II)-imprinted polymer layer on the surface of mag@silica led to an increase in the maximum adsorption capacity for Co(II). The mag@silica-CIP selectively adsorbed Co(II) even in the presence of competing species such as Fe(II), Ni(II), and Mn(II) ions. Thermodynamic experiments revealed that the adsorption of Co(II) by mag@silica-CIP is an endothermic and spontaneous process. Lee, Hyun-Kyu; Choi, Jung-Weon; Choi, Sang-June Kyungpook Natl Univ, Res Inst Adv Energy Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Architectural Civil Environm & Energy Engn, Daegu, South Korea sjchoi@knu.ac.kr; SEPARATION SCIENCE AND TECHNOLOGY SEP SCI TECHNOL 0149-6395 1520-5754 56 11 SCIE CHEMISTRY, MULTIDISCIPLINARY;ENGINEERING, CHEMICAL 2021 2.799 55.6 17 Cobalt; ion-imprinted polymer; mesoporous silica; selectivity; adsorption AQUEOUS-SOLUTION; PB(II); COPPER; NANOPARTICLES; RECOGNITION; ADSORPTION; EXTRACTION; ADSORBENT; TRANSPORT; KINETICS English 2021 2021-07-24 10.1080/01496395.2020.1797798 바로가기 바로가기 바로가기
Article Penalizing 'runaway' migrant wives: commercial cross-border marriages and home space as confinement This study examines the use of the term 'gachul (absconding from home)' in courts and immigration policies to punish the behavior of marriage migrant women who enter South Korea after marriage and then leave their husbands. The study focuses on penalized mobility outside migrants' marital homes, which is interpreted as deviance from the expected family role. By conceptualizing home as a confinable space, the paper discusses migrant women's exclusion from citizenship based on their contribution to the family. The paper draws from cases heard in criminal courts and laws and policies, paying attention to the conflation of criminal, immigration, and family laws and the effect on marriage and family. Notably, it highlights cases of uxoricide, marital rape, and international child abduction. The cases reveal that judicial and executive bodies penalize marriage migrants' departure from home, regardless of the justification for their actions. Yi, Sohoon Kyungpook Natl Univ, Dept Sociol, Daegu, South Korea Yi, Sohoon/AAS-7454-2020 57191161678 sohoon.yi@knuac.kr;sohoon.yi@knu.ac.kr; CITIZENSHIP STUDIES CITIZENSHIP STUD 1362-1025 1469-3593 25 7 SSCI POLITICAL SCIENCE 2021 1.797 55.6 0.26 2025-07-30 5 3 Marriage migration; criminalization; immigration policies; divorce; domestic violence SOCIAL REPRODUCTION; MIGRATION; CITIZENSHIP; IMMIGRATION; ILLEGALITY; FAMILY criminalization; divorce; domestic violence; immigration policies; Marriage migration South Korea; border region; crime; divorce; domestic violence; immigration policy; international migration; marriage English 2021 2021-10-03 10.1080/13621025.2021.1968682 바로가기 바로가기 바로가기 바로가기
Article Augmenting the Delsarte bound: A forbidden interval for the order of maximal cliques in strongly regular graphs In this paper, we study the order of a maximal clique in an amply regular graph with a fixed smallest eigenvalue by considering a vertex that is adjacent to some (but not all) vertices of the maximal clique. As a consequence, we show that if a strongly regular graph contains a Delsarte clique, then the parameter mu is either small or large. Furthermore, we obtain a cubic polynomial that assures that a maximal clique in an amply regular graph is either small or large (under certain assumptions). Combining this cubic polynomial with the claw-bound, we rule out an infinite family of feasible parameters (v, k, lambda, mu) for strongly regular graphs. Lastly, we provide tables of parameters (v, k, lambda, mu) for nonexistent strongly regular graphs with smallest eigenvalue -4, -5, -6 or -7. (C) 2021 Elsevier Ltd. All rights reserved. Greaves, Gary R. W.; Koolen, Jack H.; Park, Jongyook Nanyang Technol Univ, Sch Phys & Math Sci, 21 Nanyang Link, Singapore 637371, Singapore; Univ Sci & Technol China, Sch Math Sci, 96 Jinzhai Rd, Hefei 230026, Anhui, Peoples R China; Univ Sci & Technol China, CAS Wu Wen Tsun Key Lab Math, 96 Jinzhai, Hefei 230026, Anhui, Peoples R China; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea Greaves, Gary/K-1072-2016 gary@ntu.edu.sg;koolen@ustc.edu.cn;jongyook@knu.ac.kr; EUROPEAN JOURNAL OF COMBINATORICS EUR J COMBIN 0195-6698 1095-9971 97 SCIE MATHEMATICS 2021 0.89 55.7 2 English 2021 2021-10 10.1016/j.ejc.2021.103384 바로가기 바로가기 바로가기
Correction Reconfiguring graph homomorphisms on the sphere (vol 86, 103086, 2020) Lee, Jae-Baek; Noel, Jonathan A.; Siggers, Mark Kyungpook Natl Univ, Coll Nat Sci, Daegu 702701, South Korea; Univ Warwick, Dept Comp Sci, Coventry CV4 7AL, W Midlands, England; Univ Warwick, DIMAP, Coventry CV4 7AL, W Midlands, England Lee, Juhyung/JQV-8143-2023 57201389745; 36998759100; 14519683600 mhsiggers@knu.ac.kr; EUROPEAN JOURNAL OF COMBINATORICS EUR J COMBIN 0195-6698 1095-9971 94 SCIE MATHEMATICS 2021 0.89 55.7 0 2025-07-30 0 0 English 2021 2021-05 10.1016/j.ejc.2020.103296 바로가기 바로가기 바로가기 바로가기
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Publication Year 논문이 출판된 연도입니다.
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