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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article The Role of Event-Related Rumination and Perceived Social Support on Psychological Distress during the COVID-19 Pandemic: Results from Greater Daegu Region in South Korea Objective Research on psychological distress from the coronavirus disease 2019 (COVID-19) crisis has increased significantly, but the factors that can exacerbate or mitigate such distress have remained underexplored. To address the research gap, this study examined whether two types of rumination and perceived social support predict psychological distress during the pandemic. Methods Participants were recruited from communities of the greater Daegu area (n=316) where the first massive outbreak in South Korea occurred and most residents underwent substantial disruption of daily life. They completed self-report questionnaires that included measures of psychological distress, event-related rumination, and social support. Results The hierarchical regression analysis showed that maladaptive intrusive rumination and perceived social support predicted increases and decreases in psychological distress, respectively, even when subjective severity of COVID-19-related experiences was controlled. Putatively adaptive type of rumination (i.e., deliberate rumination) was not a significant predictor concurrently. Conclusion This is among the early endeavors to comprehensively understand risk and protective factors associated with an effective coping strategy against the COVID-19 crisis. Our results indicate that intrusive rumination aggravates but social support mitigates psychological distress during the pandemic, indicating that we can better adapt by differently attending to recent experiences and maintaining perceived social support. Kang, Hyo Shin; Kim, Bin-Na Kyungpook Natl Univ, Dept Psychol, Daegu, South Korea; Gachon Univ, Dept Psychol, 1342 Seongnam Daero, Seongnam 13120, South Korea 57219595147; 56125185200 shinebinna@gachon.ac.kr; PSYCHIATRY INVESTIGATION PSYCHIAT INVEST 1738-3684 1976-3026 18 5 SCIE;SSCI PSYCHIATRY 2021 3.202 54.2 0.83 2025-07-30 16 15 COVID-19; Mental health; Intrusive rumination; Social support POSTTRAUMATIC GROWTH; NATURAL DISASTER; MENTAL-HEALTH; PREDICTORS; US COVID-19; Intrusive rumination; Mental health; Social support adult; aged; anxiety; Article; Brief Symptom Inventory; coping behavior; coronavirus disease 2019; depression; digestive system disease assessment; disease severity; distress syndrome; educational status; event related rumination inventory; female; human; human experiment; Likert scale; male; mental health; mental stress; Multidimensional Scale of Perceived Social Support; pandemic; questionnaire; rumination; social support; somatization; South Korea English 2021 2021-05 10.30773/pi.2020.0455 바로가기 바로가기 바로가기 바로가기
Review A mini-review on the effects of COVID-19 on younger individuals Coronavirus disease 2019 (COVID-19) pandemic has uprooted our lives like never before since its onset in the late December 2019. The world has seen mounting infections and deaths over the past few months despite the unprecedented measures countries are implementing, such as lockdowns, social distancing, mask-wearing, and banning gatherings in large groups. Interestingly, young individuals seem less likely to be impacted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19. While the rate of transmission, symptom presentation, and fatality is lower in children than people from other age groups, they have been disproportionately affected by strict lockdown measures needed to curb viral spread. In this review, we describe the association between patient age and COVID-19, epidemiology of SARS-CoV-2 infection in children, psychological effects associated with lockdowns and school closures, and possible mechanisms underlying lower transmission rate of COVID-19 in children. Manivannan, Madhumitha; Jogalekar, Manasi P.; Kavitha, Muthu Subash; Maran, Balu Alagar Venmathi; Gangadaran, Prakash Elgin Acad, Elgin, IL 60120 USA; Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA; Hiroshima Univ, Grad Sch Adv Sci & Engn, Hiroshima 7398511, Japan; Univ Malaysia Sabah, Borneo Marine Res Inst, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia; Kyungpook Natl Univ, Sch Med, Dept Nucl Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, Plus KNU Biomed Convergence Program BK21, Daegu 41944, South Korea Gangadaran, Prakash/AAV-3102-2021; Venmathi Maran, Balu Alagar/G-5163-2014; Kavitha, M.S./AAI-6438-2020; Jogalekar, Manasi/AAG-6925-2020 58458546400; 57194462336; 57218147465; 58789989400; 54393130400 bavmaran@ums.edu.my;prakashg@knu.ac.kr; EXPERIMENTAL BIOLOGY AND MEDICINE EXP BIOL MED 1535-3702 1535-3699 246 3 SCIE MEDICINE, RESEARCH & EXPERIMENTAL 2021 4.088 54.3 1.16 2025-07-30 37 41 COVID-19; younger individuals; SARS-CoV-2; immune system; psychology; education UNITED-STATES; CHILDREN COVID-19; education; immune system; psychology; SARS-CoV-2; younger individuals Adolescent; Age Distribution; Child; Communicable Disease Control; COVID-19; Humans; SARS-CoV-2; Schools; antibiotic agent; corticosteroid; ferritin; influenza vaccine; programmed death 1 receptor; troponin; adult; aged; child; coronavirus disease 2019; disease transmission; education; fatality; fever; groups by age; health disparity; human; hysteria; immune response; immune system; myocarditis; myositis; nephrotic syndrome; prevalence; psychology; public health; Review; SARS coronavirus; social behavior; adolescent; age distribution; communicable disease control; epidemiology; pathogenicity; procedures; school English 2021 2021-02 10.1177/1535370220975118 바로가기 바로가기 바로가기 바로가기
Article Non-thermal plasma application enhances the recovery of transected sciatic nerves in rats This experimental research aimed to investigate the effects of non-thermal plasma on nerve regeneration after transected nerve damage using the sciatic nerve in Wistar albino (A) rats. The experiments were performed on 27 Wistar A rats. The rats underwent surgery for right sciatic nerve exposure and were divided into three groups (each group, n = 9) according to sciatic nerve transected injury (SNTI) and non-thermal plasma application: a non-nerve damage (non-ND) group, a only nerve damage without non-thermal plasma application (ND) group, and a nerve damage with non-thermal plasma application (ND + NTP) group. Subsequent to SNTI and immediate suture, non-thermal plasma was administered three times per week for eight weeks. Evaluation for functional recovery was performed using the static sciatic index measured over the full treatment period of eight weeks. The sciatic nerve specimens were obtained after euthanasia and third day from the last non-thermal plasma application. The sciatic nerve tissues were subjected to histological analysis. Behavior analysis presented that the ND + NTP group showed improved static sciatic index compared with the nerve damage group. Histopathological findings demonstrated that the ND + NTP group had more dense Schwann cells and well-established continuity of nerve fibers, greater than the nerve damage group. Immunohistochemistry showed that the ND + NTP group had increased levels of markers for microtubule-associated protein 2 (MAP2), tau, S100 calcium-binding protein B, and neurofilament-200 and regulated the overexpression of CD68 and MAP2. These results indicated that non-thermal plasma enhanced the motor function and restored the neuronal structure by accelerating myelination and axonal regeneration. Additionally, non-thermal plasma was confirmed to have a positive effect on the recovery of SNTI in rats. Lee, Sung-Tak; Jang, Yoon-Seo; Kim, Uk-Kyu; Kim, Hyung-Joon; Ryu, Mi-Heon; Kim, Gyoo-Cheon; Hwang, Dae-Seok Kyungpook Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, Daegu 41940, South Korea; Pusan Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, Gyeongnam 50612, South Korea; Pusan Natl Univ, Sch Dent, Dept Oral Physiol, BK21 Plus Project, Gyeongnam 50612, South Korea; Pusan Natl Univ, Sch Dent, Inst Translat Dent Sci, Gyeongnam 50612, South Korea; Pusan Natl Univ, Sch Dent, Dept Oral Pathol, BK21 Plus Project, Gyeongnam 50612, South Korea; Pusan Natl Univ, Sch Dent, Dept Dent Anat, BK21 Plus Project, Gyeongnam 50612, South Korea Kim, Hyung Joon/ABD-3143-2020 55931708300; 57216875517; 7102248962; 57102658200; 35771492000; 7403064124; 16835304000 dshwang@pusan.ac.kr; EXPERIMENTAL BIOLOGY AND MEDICINE EXP BIOL MED 1535-3702 1535-3699 246 11 SCIE MEDICINE, RESEARCH & EXPERIMENTAL 2021 4.088 54.3 0.43 2025-07-30 10 10 Nerve regeneration; nerve repair; non-thermal atmospheric-pressure plasma; cold plasma; plasma medicine; sciatic nerve injury of rat ATMOSPHERIC-PRESSURE PLASMA; AXONAL REGENERATION; BARRIER DISCHARGE; INJURY; FIBER; MICE; CELL; MACROPHAGES; INHIBITION; APOPTOSIS cold plasma; Nerve regeneration; nerve repair; non-thermal atmospheric-pressure plasma; plasma medicine; sciatic nerve injury of rat Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Axons; Macrophages; Male; Myelin Sheath; Nerve Regeneration; Plasma Gases; Rats, Wistar; Schwann Cells; Sciatic Nerve; Time Factors; CD68 antigen; methionyl aminopeptidase; microtubule associated protein 2; protein S100B; tau protein; axon; CD68 protein, rat; differentiation antigen; leukocyte antigen; animal experiment; animal model; Article; atmospheric pressure; cell proliferation; cold stress; controlled study; euthanasia; food intake; gene overexpression; histopathology; immunofluorescence; immunohistochemistry; male; microtubule; motor performance; muscle action potential; muscle contraction; myelin sheath; myelination; nerve block; nerve fiber regeneration; nerve injury; nerve regeneration; neurofilament; nonhuman; outcome assessment; plasma gas; protein expression; rat; sciatic nerve; animal; chemistry; cytology; drug effect; injury; macrophage; metabolism; pharmacology; physiology; plasma gas; Schwann cell; sciatic nerve; time factor; Wistar rat English 2021 2021-06 10.1177/1535370221996655 바로가기 바로가기 바로가기 바로가기
Review Recent developments in autophagy-targeted therapies in cancer Autophagy plays a crucial role in cellular development and differentiation as well as in the maintenance of homeostasis in healthy cells. Autophagy is well documented in neurodegenerative disorders, aging, and infectious diseases. However, recognizing its significance in cancer has always been challenging due to its tumor-promoting and suppressive attributes. Various modulators targeting key components of autophagy machinery directly or indirectly have been developed over the years, and have shown promising results in preclinical models. Some of these compounds are even being tested in clinical trials for safety and efficacy. A detailed review of strategies used to target autophagy in cancer is presented including our opinion on developing better therapies and outstanding issues. Jogalekar, Manasi P.; Veerabathini, Anurag; Gangadaran, Prakash Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA; Maxim Integrated Prod Inc, Chandler, AZ 85225 USA; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Nucl Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu 41944, South Korea Gangadaran, Prakash/AAV-3102-2021; Jogalekar, Manasi/AAG-6925-2020 57194462336; 57216493774; 54393130400 prakashg@knu.ac.kr; EXPERIMENTAL BIOLOGY AND MEDICINE EXP BIOL MED 1535-3702 1535-3699 246 2 SCIE MEDICINE, RESEARCH & EXPERIMENTAL 2021 4.088 54.3 0.35 2025-07-30 16 18 Autophagy; cancer; Beclin-1; mTOR; chloroquine REGULATES AUTOPHAGY; BECLIN 1; EXPRESSION; MACHINERY; HYDROGEL; SURVIVAL; PROTEIN; ATG12 Autophagy; Beclin-1; cancer; chloroquine; mTOR Animals; Autophagy; Clinical Trials as Topic; Disease Progression; Genes, Tumor Suppressor; Humans; Molecular Targeted Therapy; Neoplasms; beclin 1; binimetinib; capecitabine; carboplatin; carfilzomib; dabrafenib; dexamethasone; DNA vaccine; docetaxel; entinostat; etoposide; everolimus; gemcitabine; hydroxychloroquine; itraconazole; letrozole; microRNA; paclitaxel; palbociclib; peroxisome proliferator activated receptor alpha; phosphatidylinositol 3 kinase; rapamycin; reactive oxygen metabolite; regorafenib; sorafenib; sunitinib; trametinib; transcription factor EZH2; vorinostat; angiogenesis; apoptosis; autophagosome; autophagy (cellular); calcium signaling; cancer immunotherapy; cancer resistance; cancer risk; cancer therapy; carcinogenesis; cell maturation; cell proliferation; cell survival; chronic myeloid leukemia; colorectal cancer; cytotoxicity; genomic instability; glucose transport; homeostasis; human; immune response; molecularly targeted therapy; natural killer cell; overall survival; Review; signal transduction; tumor growth; tumor microenvironment; animal; autophagy; clinical trial (topic); disease exacerbation; genetics; neoplasm; pathology; tumor suppressor gene English 2021 2021-01 10.1177/1535370220966545 바로가기 바로가기 바로가기 바로가기
Review SARS-CoV-2 variants: A double-edged sword? Since the worldwide emergence of the COVID-19 outbreak, there have been international concerns about the possible viral evolution into variants with underlying mutations that may contribute to their increased transmissibility, disease severity, risk of death, and their potential escape from the immune response or may even lead to its extinction. Rigorous surveillance has revealed the variants harboring mutations in the spike protein, the main target of neutralizing antibodies generated through vaccination or herd immunity. In this review, we have highlighted major SARS-CoV-2 variants as well as other local strains along with their specific mutations, suspected changes in their characteristics, and their impact on the current pandemic and vaccine efficacy. We have also emphasized the need to develop widely protective interventions to curb further transmission of variants. Jogalekar, Manasi P.; Veerabathini, Anurag; Gangadaran, Prakash Brigham & Womens Hosp, Boston, MA 02115 USA; Maxim Integrated Prod Inc, Chandler, AZ 85225 USA; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 KNU Convergence Educ Program Biomed Sci Crea, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Nucl Med, Daegu 41944, South Korea ; Jogalekar, Manasi/AAG-6925-2020; Gangadaran, Prakash/AAV-3102-2021 57194462336; 57216493774; 54393130400 mjogalekar@bwh.harvard.edu; EXPERIMENTAL BIOLOGY AND MEDICINE EXP BIOL MED 1535-3702 1535-3699 246 15 SCIE MEDICINE, RESEARCH & EXPERIMENTAL 2021 4.088 54.3 0.61 2025-07-30 19 21 COVID-19; SARS-CoV-2; spike protein; mutations; variants; B; 1; 1; 7 COVID-19 B.1.1.7; COVID-19; mutations; SARS-CoV-2; spike protein; variants COVID-19; COVID-19 Vaccines; Host-Pathogen Interactions; Humans; Mutation; SARS-CoV-2; ad26.cov2.s vaccine; aspartic acid; convalescent plasma; influenza vaccine; monoclonal antibody; neutralizing antibody; nvx-cov2373 vaccine; SARS-CoV-2 vaccine; virus spike protein; antibody response; behavior assessment; coronavirus disease 2019; disease severity; disease transmission; drug efficacy; gene mutation; genetic variability; herd immunity; immune response; mortality; pandemic; Review; SARS-CoV-2 variant 501Y.V2; SARS-CoV-2 variant 796h; SARS-CoV-2 variant n501y; SARS-CoV-2 variant P.1 501y.V3; upper respiratory tract; vaccination; virus entry; virus replication; epidemiology; genetics; host pathogen interaction; human; mutation; pathogenicity; pharmacology; prevention and control English 2021 2021-08 10.1177/15353702211014146 바로가기 바로가기 바로가기 바로가기
Editorial Material A Case of Vesicobullous Rheumatoid Neutrophilic Dermatosis Ha, Dae-Lyong; Shin, Kihyuk; Kim, Hoon-Soo; Ko, Hyun-Chang; Kim, Byung-Soo; Kim, Moon-Bum Pusan Natl Univ, Sch Med, Dept Dermatol, Busan, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Kyungpook Natl Univ, Sch Med, Dept Dermatol, Daegu, South Korea Ko, Hyun-chang/ABF-7418-2021 57201367090; 57218366956; 57206211956; 57202265435; 55726523900; 7406088339 dhwl222@naver.com;teriakiller@hanmail.net;suekimm@hanmail.net;hcko@pusan.ac.kr;dockbs@pusan.ac.kr;drkmp@hanmail.net; JCR-JOURNAL OF CLINICAL RHEUMATOLOGY JCR-J CLIN RHEUMATOL 1076-1608 1536-7355 27 3 SCIE RHEUMATOLOGY 2021 3.902 54.4 0.93 2025-07-30 2 2 Humans; Neutrophils; Sweet Syndrome; methotrexate; nonsteroid antiinflammatory agent; adult; arthralgia; case report; clinical article; clinical feature; disease activity; disease course; disease duration; female; histopathology; human; human tissue; joint swelling; middle aged; neutrophil chemotaxis; Note; rash; rheumatoid arthritis; skin defect; skin disease; skin manifestation; vesicobullous rheumatoid neutrophilic dermatosis; acute febrile neutrophilic dermatosis; neutrophil English 2021 2021-04 10.1097/rhu.0000000000001292 바로가기 바로가기 바로가기 바로가기
Article Structural Flexibility of Peripheral Loops and Extended C-terminal Domain of Short Length Substrate Binding Protein from Rhodothermus marinus Substrate binding proteins (SBPs) bind to specific ligands in the periplasmic regions of cells and then bind to membrane proteins to participate in transport or signal transduction. Typically, SBPs consist of two alpha/beta domains and recognize the substrate by a flexible hinge region between the two domains. Conversely, the short-length SBPs are often observed in protein databases, which are located around methyl-accepting chemotaxis protein genes. We previously determined the crystal structure of Rhodothermus marinus SBP (named as RmSBP), consisting of a single alpha/beta domain; however, the substrate recognition mechanism is still unclear. To better understand the functions of short length RmSBP, we performed a comprehensive study, involving comparative structure analysis, computational substrate docking, and X-ray crystallographic data. RmSBP shares a high level of similarity in the alpha/beta domain region with other SBPs, but it has a distinct topology in the C-terminal domain. The substrate binding model suggested that conformational changes in the peripheral region of RmSBP was required to recognize the substrate. We determined the crystal structures of RmSBP at pH 5.5, 6.0, and 7.5. RmSBP showed structural flexibility in the beta 1-alpha 2 loop, beta 5-beta 6 loop, and extended C-terminal domains, based on the electron density map and temperature B-factor analysis. These results provide information that will further our understanding on the functions of the short length SBP. Bae, Ji-Eun; Kim, In Jung; Xu, Yongbin; Nam, Ki Hyun Kyungpook Natl Univ, Sch Life Sci, KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, KNU Inst Microorganisms, Daegu 41566, South Korea; Korea Univ, Div Biotechnol, Seoul 02841, South Korea; Dalian Minzu Univ, Coll Life Sci, Dept Bioengn, Dalian 116600, Liaoning, Peoples R China; Dalian Minzu Univ, Key Lab Biotechnol & Bioresources Utilizat, Minist Educ, Dalian 116024, Peoples R China; Pohang Univ Sci & Technol, Dept Life Sci, Pohang 37673, South Korea; Ernst Moritz Arndt Univ Greifswald, Inst Biochem, Dept Biotechnol & Enzyme Catalysis, D-17487 Greifswald, Germany Yongbin, Xu/AAS-8750-2020; Nam, Ki Hyun/N-6812-2019 57190605352; 57195531808; 23092421400; 13808340200 structures@postech.ac.kr; PROTEIN JOURNAL PROTEIN J 1572-3887 1875-8355 40 2 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY 2021 4 54.4 0.35 2025-07-30 5 5 Substrate-binding protein; SBP; ABC transport; alpha/beta domain; Rhodothermus marinus; SARS-CoV-2 ABC transport; Rhodothermus marinus; SARS-CoV-2; SBP; Substrate-binding protein; α/β domain Bacterial Proteins; Crystallography, X-Ray; Protein Binding; Protein Conformation; Rhodothermus; bacterial protein; protein binding; article; carboxy terminal sequence; conformational transition; crystal structure; factor analysis; molecular recognition; nonhuman; protein domain; Rhodothermus; Severe acute respiratory syndrome coronavirus 2; structure analysis; X ray crystallography; metabolism; protein conformation; Rhodothermus English 2021 2021-04 10.1007/s10930-021-09970-z 바로가기 바로가기 바로가기 바로가기
Article A Practical Methodology for Waste-to-Energy Facilities to Screen Toxic Combustible Wastes and Priority Metals Waste-to-energy technology is an alternative way to reduce fossil fuels and to secure energy resources. This technology can be readily applied to our real society because non-recyclable but combustible wastes are generated every day and the technology is already available and mature as shown in many facilities for waste incineration. However, this technology incurs environmental and human health concerns due to toxic metals in wastes, which have not been effectively managed because metal- and waste-related risk assessment is too time- and resource-consuming for field facilities. Thus, this study suggests a practical methodology to effectively screen toxic combustible wastes and to identify priority metals to be targeted for pollution prevention; and carries out a case study to demonstrate the methodology. The methodology is based on the assessment of toxicity potentials (for instance, cancer, non-cancer, and eco-toxicity potentials) from metals in combustible wastes on a per-energy basis. The toxicity potential is quantified by using (i) the metal contents and lower heating value (LHV) of a combustible waste and (ii) the characterization factors accounting for the fate, exposure, and effect of metals. A case study is performed by applying the methodology to waste cable coating, waste engine oil, waste paint, refuse-derived fuel (RDF), refuse plastic fuel (RPF), waste medium-density fiberboard (MDF), and wastewater sludge. The case study results showed that the cable coating, engine oil, brown paint, RDF, and wastewater sludge had relatively high toxicity potentials, and their priority metals were lead (Pb), zinc, and copper. This study can be used for waste-to-energy facilities to practically screen toxic waste fuels and to determine post-treatment processes that can effectively remove priority metals. [GRAPHICS] . Kim, Hyeoung-Seok; Park, Myoung-Gyun; Yeon, Eung-Jae; Lee, Dae Sung; Lim, Seong-Rin Kangwon Natl Univ, Dept Environm Engn, Coll Engn, Chunchon 24341, Gangwon, South Korea; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea 57218921110; 57218918558; 57218919803; 55568524907; 14626162700 daesung@knu.ac.kr;srlim@kangwon.ac.kr; WASTE AND BIOMASS VALORIZATION WASTE BIOMASS VALORI 1877-2641 1877-265X 12 6 SCIE ENVIRONMENTAL SCIENCES 2021 3.449 54.7 0.09 2025-07-30 1 2 Combustible waste; Metal; Toxicity potential; Waste-to-energy MUNICIPAL SOLID-WASTE; POTENTIAL ENVIRONMENTAL IMPACTS; SEWAGE-SLUDGE; POLLUTION PREVENTION; TRACE-ELEMENTS; HEAVY-METALS; FLY-ASH; SYSTEM; SOIL; COCOMBUSTION Combustible waste; Metal; Toxicity potential; Waste-to-energy Diseases; Engines; Fossil Fuels; Metals; Paint; Risk Assessment; Cable sheathing; Calorific value; Diseases; Engines; Environmental technology; Fossil fuels; Health risks; Lubricating oils; Metals; Paint; Refuse derived fuels; Risk assessment; Toxicity; Waste treatment; Wastes; Zinc coatings; Characterization factors; Combustible wastes; Human health concerns; Lower heating value; Pollution prevention; Post-treatment process; Waste medium density fiberboards; Waste to energy technologies; Waste incineration English 2021 2021-06 10.1007/s12649-020-01223-x 바로가기 바로가기 바로가기 바로가기
Article Peroxiredoxin-6 regulates p38-mediated epithelial-mesenchymal transition in HCT116 colon cancer cells Background: Peroxiredoxins (Prxs) are antioxidant enzymes that protect cells from oxidative stress induced by several factors. They regulate several signaling pathways, such as metabolism, immune response, and intracellular reactive oxygen species (ROS) homeostasis. Epithelial-mesenchymal transition (EMT) is a transforming process that induces the loss of epithelial features of cancer cells and the gain of the mesenchymal phenotype. The EMT promotes metastasis and cancer cell progression mediated by several pathways, such as mitogen-activated protein kinases (MAPKs) and epigenetic regulators. Methods: We used Prx6 overexpressed and downregulated HCT116 cells to study the mechanism between Prx6 and colon cancer. The expression of Prx6, GAPDH, Snail, Twist1, E-cadherin, Vimentin, N-cadherin, ERK, p-ERK, p38, p-p38, JNK, and p-JNK were detected by Western blotting. Additionally, an animal study for xenograft assay was conducted to explore the function of Prx6 on tumorigenesis. Cell proliferation and migration were determined by IncuCyte Cell Proliferation and colony formation assays. Results: We confirmed that the expression of Prx6 and EMT signaling highly occurs in HCT116 compared with that in other colon cancer cell lines. Prx6 regulates the EMT signaling pathway by modulating EMT-related transcriptional repressors and mesenchymal genes in HCT116 colon cancer cells. Under the Prx6-overexpressed condition, HCT116 cells proliferation increased significantly. Moreover, the HCT116 cells proliferation decreased in the siPrx6-treated cells. Eleven days after HCT116 cell injection, Prx6 was overexpressed in the HCT116-injected mice, and the tumor volume increased significantly compared with that of the control mice. Furthermore, Prx6 regulates EMT signaling through p38 phosphorylation in colon cancer cells. Conclusion: We suggested that Prx6 regulates EMT signaling pathway through p38 phosphorylation modulation in HCT116 colon cancer cells. Chae, Unbin; Kim, Bokyung; Kim, HanSeop; Park, Young-Ho; Lee, Seung Hwan; Kim, Sun-Uk; Lee, Dong-Seok Korea Res Inst Biosci & Biotechnol KRIBB, Futurist Anim Resource & Res Ctr, Cheongju 28116, South Korea; Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea; Korea Univ Sci & Technol UST, KRIBB Sch Biosci, Dept Funct Genom, Daejeon 34113, South Korea; Korea Res Inst Biosci & Biotechnol KRIBB, Natl Primate Res Ctr NPRC, Cheongju 28116, South Korea Kim, Sunuk/KJM-5211-2024 56414782600; 57205869587; 57203630238; 56246852400; 57202327400; 8278891100; 57210068061 lee1@knu.ac.kr; JOURNAL OF BIOLOGICAL RESEARCH-THESSALONIKI J BIOL RES-THESSALON 1790-045X 2241-5793 28 1 SCIE BIOLOGY 2021 2.576 54.8 0.59 2025-07-30 7 8 Colon cancer; Epithelial-mesenchymal transition (EMT); HCT116; p38; Peroxiredoxin 6 (Prx6) SIGNALING PATHWAYS; OVEREXPRESSION; APOPTOSIS; ACTIVATION; EXPRESSION; PROTEIN; BALANCE; PRDX6 Colon cancer; Epithelial–mesenchymal transition (EMT); HCT116; p38; Peroxiredoxin 6 (Prx6) English 2021 2021-11-23 10.1186/s40709-021-00153-6 바로가기 바로가기 바로가기 바로가기
Article Varadia, a new helicarionoidean semi-slug genus from India's Western Ghats (Stylommatophora: Helicarionoidea) We here describe a new Indian helicarionoidean genus, Varadia Bhosale & Raheem gen. nov., containing the single species Varadia amboliensis Bhosale, Thackeray, Muley & Raheem gen. et sp. nov. This new semi-slug is endemic to the northern and central Western Ghats and is primarily a forest-living species. We describe and figure the shell, reproductive system, radula, spermatophore and external morphology of this new species, and detail its known distribution. We explore its relationships to other helicarionoideans using phylogenetic analyses of DNA sequence data for part of the ribosomal RNA gene cluster and discuss the morphology of the new genus in relation to other, primarily South Indian, helicarionoidean taxa. Based on characters of the reproductive system, particularly the male genitalia and the gametolytic sac, we provisionally place Varadia gen. nov. in the Macrochlamydinae (Ariophantidae). This is consistent with the results of our molecular phylogenetic analyses. The combination of large size, broad, densely tuberculated shell lobes and a shell with ca 4 whorls and a disproportionately large body whorl makes V. amboliensis gen. et sp. nov. unique among the helicarionoidean taxa of the Western Ghats. The new semi-slug is also highly distinctive in the morphology of its male genitalia. Bhosale, Amrut R.; Saadi, Ahmed J.; Wade, Christopher M.; Thackeray, Tejas U.; Tamboli, Asif S.; Kadam, Suhas K.; Muley, Dipak, V; Raheem, Dinarzarde C. Shivaji Univ, Dept Zool, Kolhapur 416004, Maharashtra, India; Sadguru Gadage Maharaj Coll, Dept Zool, Karad, India; Fdn Biodivers Conservat, A1903, Pune 411041, Maharashtra, India; Univ Nottingham, Sch Life Sci, Univ Pk, Nottingham NG7 2RD, England; Univ Vienna, Dept Evolutionary Biol, Unit Integrat Zool, UZA1 Althanstr 14, A-1090 Vienna, Austria; Thackeray Wildlife Fdn, Mumbai 400051, Maharashtra, India; Shivaji Univ, Dept Biochem, Kolhapur 416004, Maharashtra, India; Kyungpook Natl Univ, Sch Life Sci, Res Inst Dok Do & Ulleung Do Isl, Dept Biol, 80 Daehak Ro, Daegu 41566, South Korea; Nat Hist Museum, Dept Life Sci, London SW7 5BD, England Tamboli, Asif/HJB-2803-2022; Kadam, Dr Suhas/HNI-6437-2023; Saadi, Ahmed/GPK-2090-2022; Kadam, Dr. Suhas/HNI-6437-2023 56730426700; 57209252892; 7102531607; 57164002400; 56974034100; 57188723669; 6602319157; 12752102300 amrutb18@gmail.com;ahmed.saadi@nottingham.ac.uk;chris.wade@nottingham.ac.uk;tejasthackeray@gmail.com;asift456@gmail.com;suhas397@gmail.com;drdvmuley@gmail.com;d.raheem@nhm.ac.uk; EUROPEAN JOURNAL OF TAXONOMY EUR J TAXON 2118-9773 757 SCIE ENTOMOLOGY;PLANT SCIENCES;ZOOLOGY 2021 1.398 54.8 0.67 2025-07-30 8 6 Varadia amboliensis gen. et sp. nov.; Macrochlamydinae; taxonomy; phylogenetics; ribosomal RNA gene cluster SENSU-LATO GASTROPODA; LAND SNAILS; AUSTRALIAN HELICARIONIDAE; EVOLUTIONARY RELATIONSHIPS; MOLECULAR PHYLOGENY; SYSTEMATIC REVISION; PULMONATA; LIMACOIDEA; ARIOPHANTIDAE; CONFIDENCE Macrochlamydinae; Phylogenetics; Ribosomal RNA gene cluster; Taxonomy; Varadia amboliensis gen. et sp. nov English 2021 2021-06-25 10.5852/ejt.2021.757.1413 바로가기 바로가기 바로가기 바로가기
Article The effect of materialism on conspicuous vs inconspicuous luxury consumption: focused on need for uniqueness, self-monitoring and self-construal Purpose: Previous research on luxury consumption has focused on conspicuous consumption; however, research on consumers' self-conceptual mechanism in inconspicuous luxury consumption context is scarce. The present study aims to investigate various self-concepts and their mechanisms for inconspicuous and conspicuous luxury consumption. Design/methodology/approach: An experiment with 215 participants from online survey website was conducted, and the hypotheses were tested using PROCESS Macro 3.4. Findings: The study findings are as follows. Materialistic consumers' preference between inconspicuous and conspicuous luxury products is dependent on distinctive self-conceptual mechanism. More specifically, materialistic consumers with independent self-construal prefer inconspicuous luxury brands because of high need for uniqueness, whereas non-materialistic consumers with interdependent self-construal prefer conspicuous luxury products because of high self-monitoring. Research limitations/implications: The present study uniquely shows conditions (moderated mediation) that the link between need for uniqueness (self-monitoring) and luxury consumption is stronger for those with independent (interdependent) self-construal than for those with interdependent (independent) self-construal. The present results extend and help better understanding of mechanisms and conditions of conspicuous and inconspicuous luxury consumption. Practical implications: Marketers are advised to design and produce unique vs popular luxury brands depending on consumer's motives and different self-concepts. Originality/value: This research contributes to extant literature by distinguishing between conspicuous and inconspicuous luxury consumption with two different mechanisms (need for uniqueness and self-monitoring). The present study further demonstrates that the two mechanisms are strongly sustained differently depending on consumer's levels of self-construal. Lee, Minyoung; Bae, Joonheui; Koo, Dong-Mo Kyungpook Natl Univ, Sch Management, Daegu, South Korea Koo, Dong-Mo/AAG-5411-2021; Bae, Joonheui/JXM-6789-2024 57218319647; 57202349513; 14121485100 bibianna0910@naver.com;regina721@knu.ac.kr;unlimited@knu.ac.kr; ASIA PACIFIC JOURNAL OF MARKETING AND LOGISTICS ASIA PAC J MARKET LO 1355-5855 1758-4248 33 3 SSCI BUSINESS 2021 4.643 54.9 1.53 2025-07-30 38 36 Inconspicuous luxury; Self-monitor; Need for uniqueness; Self-construal; Materialism; Moderated mediation SCALE DEVELOPMENT; CONSUMERS; BRANDS; BANDWAGON; VALUES; WILLINGNESS; ANTECEDENTS; VALIDATION; ATTITUDES; COGNITION Inconspicuous luxury; Materialism; Moderated mediation; Need for uniqueness; Self-construal; Self-monitor English 2021 2021-02-23 10.1108/apjml-12-2019-0689 바로가기 바로가기 바로가기 바로가기
Article Addition of Various Cellulosic Components to Bacterial Nanocellulose: A Comparison of Surface Qualities and Crystalline Properties Bacterial nanocellulose (BNC) is a biocompatible material with a lot of potential. To make BNC commercially feasible, improvements in its production and surface qualities must be made. Here, we investigated the in situ fermentation and generation of BNC by addition of different cellulosic substrates such as Avicel and carboxymethylcellulose (CMC) and using Komagataeibacter sp. SFCB22-18. The addition of cellulosic substrates improved BNC production by a maximum of about 5 times and slightly modified its structural properties. The morphological and structural properties of BNC were investigated by using Fourier transform-infrared spectroscopy (FT-IR), scanning electron microscopy and X-ray diffraction. Furthermore, a type-A cellulose-binding protein derived from Clostridium thermocellum, CtCBD3, was used in a novel biological analytic approach to measure the surface crystallinity of the BNC. Because Avicel and CMC may adhere to microfibrils during BNC synthesis or crystallization, cellulose-binding protein could be a useful tool for identifying the crystalline properties of BNC with high sensitivity. Bang, Won Yeong; Kim, Dong Hyun; Kang, Mi Dan; Yang, Jungwoo; Huh, Taelin; Lim, Young Woon; Jung, Young Hoon Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Ildong Biosci, Pyeongtaek 17957, South Korea; Korea Univ, Grad Sch, Dept Biotechnol, Seoul 02841, South Korea; Kyungpook Natl Univ, Sch Life Sci & Biotechnol, Daegu 41566, South Korea; Seoul Natl Univ, Sch Biol Sci & Inst Microbiol, Seoul 08826, South Korea Jung, Young/F-1703-2013; Kim, Dong Hyun/LDT-2672-2024 57208701768; 55574224522; 57311023600; 56076383700; 7007119367; 7402565072; 55550063700 younghoonjung@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 10 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0.34 2025-07-30 5 5 Bacterial nanocellulose; Komagataeibacter; cellulose-binding protein; Avicel; carboxymethyl cellulose; fermentation X-RAY-DIFFRACTION; I-BETA; SCAFFOLD; CMC Avicel; Bacterial nanocellulose; Carboxymethyl cellulose; Cellulose-binding protein; Fermentation; Komagataeibacter Acetobacteraceae; Biocompatible Materials; Carboxymethylcellulose Sodium; Cellulose; Microscopy, Electron, Scanning; Nanostructures; Protein Binding; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction; bacterial nanocellulose; binding protein; carboxymethylcellulose; microcrystalline cellulose; nanocellulose; type A cellulose binding protein; unclassified drug; biomaterial; cellulose; nanomaterial; protein binding; Article; bacterium; Clostridium thermocellum; controlled study; crystallization; fermentation; fibril; Fourier transform infrared spectroscopy; Komagataeibacter; nonhuman; scanning electron microscopy; surface property; synthesis; X ray diffraction; Acetobacteraceae; chemistry; infrared spectroscopy English 2021 2021-10 10.4014/jmb.2106.06068 바로가기 바로가기 바로가기 바로가기
Article Crystal Structure and Molecular Mechanism of Phosphotransbutyrylase from Clostridium acetobutylicum Acetone-butanol-ethanol (ABE) fermentation by the anaerobic bacterium Clostridium acetobutylicum has been considered a promising process of industrial biofuel production. Phosphotransbutyrylase (phosphate butyryltransferase, PTB) plays a crucial role in butyrate metabolism by catalyzing the reversible conversion of butyryl-CoA into butyryl phosphate. Here, we report the crystal structure of PTB from the Clostridial host for ABE fermentation, C. acetobutylicum, (CaPTB) at a 2.9 angstrom resolution. The overall structure of the CaPTB monomer is quite similar to those of other acyltransferases, with some regional structural differences. The monomeric structure of CaPTB consists of two distinct domains, the N- and C-terminal domains. The active site cleft was formed at the interface between the two domains. Interestingly, the crystal structure of CaPTB contained eight molecules per asymmetric unit, forming an octamer, and the size-exclusion chromatography experiment also suggested that the enzyme exists as an octamer in solution. The structural analysis of CaPTB identifies the substrate binding mode of the enzyme and comparisons with other acyltransferase structures lead us to speculate that the enzyme undergoes a conformational change upon binding of its substrate. Kim, Sangwoo; Kim, Kyung-Jin Kyungpook Natl Univ, Sch Life Sci, BK21 Four KNU Creat BioSesearch Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, KNU Inst Microorganisms, Daegu 41566, South Korea Kim, Kyung-Jin/MVY-3405-2025 59237076700; 55510867400 kkim@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 10 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0 2025-07-30 0 0 Clostridium acetobutylicum; phosphotransbutyrylase; butyryl-CoA; butyrate metabolism PHOSPHOTRANSACETYLASE; FERMENTATION; ACETONE; BIOSYNTHESIS; EXPRESSION; PATHWAY; SWITCH; ACID Butyrate metabolism; Butyryl-coa; Clostridium acetobutylicum; Phosphotransbutyrylase Acetone; Acyl Coenzyme A; Amino Acid Sequence; Bacterial Proteins; Butanols; Catalytic Domain; Clostridium acetobutylicum; Ethanol; Fermentation; Phosphate Acetyltransferase; Protein Structure, Quaternary; acetone; acyltransferase; alcohol; butanol; phosphotransbutyrylase; unclassified drug; acyl coenzyme A; bacterial protein; butyryl-coenzyme A; phosphate acetyltransferase; ABE fermentation; amino terminal sequence; Article; biocatalysis; biosynthesis; carboxy terminal sequence; Clostridium acetobutylicum; conformational transition; crystal structure; enzyme binding; nonhuman; size exclusion chromatography; structure analysis; tetramerization; amino acid sequence; chemistry; Clostridium acetobutylicum; enzyme active site; enzymology; fermentation; metabolism; protein quaternary structure English 2021 2021-10 10.4014/jmb.2109.09036 바로가기 바로가기 바로가기 바로가기
Article Determination of Strategic Spreads in East Asia This study develops a simple spread model to explain whether market dealers behave strategically when using electronic broking services. Our spread model stresses the role of an unexpected liquidity imbalance and its volatility for inventory risk, which contrasts sharply with previous studies that emphasised price volatility as the inventory risk. To capture a dealer's strategic behaviour, we introduce a new concept of a strategic weighted spread and test this new spread using the full information maximum likelihood method with the GARCH (1,1) process. Daily spread data from 1 January 2006 to 20 December 2016 is used to explore strategic spreading at the end of a trading day in East Asia. Different effects on strategic spreads of liquidity depth in Asian financial markets are also investigated by comparing strategic spreads between the thin and deep markets. The evidence provides support for our hypothesis that a dealer behaves strategically to avoid the unexpected inventory risk, and that the magnitude of this influence depends on the depth of the financial market. Kim, Heeho; Zhang, Hongxia Kyungpook Natl Univ, Sch Econ & Trade, Daehak Ro 80, Daegu 41566, South Korea; Shandong Normal Univ, Coll Econ, Jinan, Shandong, Peoples R China ; Kim, Heeho/AAO-8809-2021 36727893700; 57199714616 kimhh@knu.ac.kr; GLOBAL ECONOMIC REVIEW GLOBAL ECON REV 1226-508X 1744-3873 50 2 SSCI ECONOMICS 2021 1.843 55.0 0 2025-07-30 1 0 Imbalanced liquidity risk; price-clustering; strategic spreads; unexpected inventory; depth of markets; East Asian markets depth of markets; East Asian markets; Imbalanced liquidity risk; price-clustering; strategic spreads; unexpected inventory English 2021 2021-04-03 10.1080/1226508x.2020.1862693 바로가기 바로가기 바로가기 바로가기
Article Diversity and Plant Growth Promotion of Fungal Endophytes in Five Halophytes from the Buan Salt Marsh The diversity and plant growth-promoting ability of fungal endophytes that are associated with five halophytic plant species (Phragmites australis, Suaeda australis, Limonium tetragonum, Suaeda glauca Bunge, and Suaeda maritima) growing in the Buan salt marsh on the west coast of South Korea have been explored. About 188 fungal strains were isolated from these plant samples' roots and were then studied with the use of the internal transcribed spacer (ITS) region (ITS1-5.8S-ITS2). The endophytic fungal strains belonged to 33 genera. Alternaria (18%) and Fusarium (12.8%), of the classes Dothideomycetes and Sordariomycetes, were most rampant in the coastal salt marsh plants. There was a higher diversity in fungal endophytes that are isolated from S. glauca Bunge than in isolates from other coastal salt marsh plants. Plant growth- promoting experiments with the use of Waito-C rice seedlings show that some of the fungal strains could encourage a more efficient growth than others. Furthermore, gibberellins (GAs) GA1, GA3, and GA9 were seen in the Sa-1-4-3 isolate (Acrostalagmus luteoalbus) culture filtrate with a gas chromatography/mass spectrometry. Khalmuratova, Irina; Choi, Doo-Ho; Yoon, Hyeok-Jun; Yoon, Tae-Myung; Kim, Jong-Guk Kyungpook Natl Univ, Sch Life Sci & Biotechnol, Daegu 701701, South Korea; Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea 55908352900; 57211275161; 24759572800; 50263701700; 35277198800 tmyoon@knu.ac.kr;kimjg@knu.ac.kr; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY J MICROBIOL BIOTECHN 1017-7825 1738-8872 31 3 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY 2021 3.277 55.0 0.84 2025-07-30 10 10 Coastal salt marsh plants; fungal endophytes; Buan salt marsh; growth promotion; gibberellin Buan salt marsh; Coastal salt marsh plants; Fungal endophytes; Gibberellin; Growth promotion Alternaria; Ascomycota; Biodiversity; DNA, Fungal; Endophytes; Fusarium; Gibberellins; Oryza; Phylogeny; Plant Growth Regulators; Plant Roots; Polymerase Chain Reaction; Republic of Korea; Salt-Tolerant Plants; Sequence Analysis, DNA; Symbiosis; Wetlands; gibberellin; gibberellin 1; gibberellin 3; gibberellin 9; internal transcribed spacer; unclassified drug; fungal DNA; phytohormone; Acrostalagmus luteoalbus; Alternaria; Amaranthaceae; Article; biodiversity; controlled study; Dothideomycetes; endophytic fungus; fungal strain; fungus; fungus isolation; Fusarium; halophyte; Limonium tetragonum; mass fragmentography; nonhuman; Phragmites australis; plant growth; plant root; Plumbaginaceae; salt marsh; Sordariomycetes; South Korea; Suaeda australis; Suaeda glauca; Suaeda maritima; Alternaria; Ascomycetes; biodiversity; classification; DNA sequence; endophyte; Fusarium; genetics; growth, development and aging; halophyte; isolation and purification; metabolism; microbiology; Oryza; phylogeny; polymerase chain reaction; symbiosis; wetland English 2021 2021-03 10.4014/jmb.2012.12041 바로가기 바로가기 바로가기 바로가기
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IF (Impact Factor) 저널 영향력 지수. 최근 2년간 발표된 논문이 해당 연도에 평균적으로 인용된 횟수를 나타냅니다. 저널의 학술적 영향력을 나타내는 대표적인 지표입니다.
JCR (%) 해당 카테고리에서 저널이 위치하는 상위 백분율입니다. 값이 낮을수록 우수한 저널임을 의미합니다 (예: 5%는 상위 5%를 의미).
FWCI Field-Weighted Citation Impact. 분야별 가중 인용 영향력 지수입니다. 논문이 받은 인용을 동일 분야, 동일 연도, 동일 문헌 유형의 평균과 비교한 값입니다. 1.0이 평균이며, 1.0보다 높으면 평균 이상의 인용을 받았음을 의미합니다.
FWCI UpdateDate FWCI 값이 마지막으로 업데이트된 날짜입니다. FWCI는 인용이 누적됨에 따라 주기적으로 업데이트됩니다.
WOS Citation Web of Science에서 집계된 해당 논문의 총 인용 횟수입니다.
SCOPUS Citation SCOPUS에서 집계된 해당 논문의 총 인용 횟수입니다.
Keywords (WoS) 저자가 논문에서 직접 지정한 키워드입니다. Web of Science에 등록된 저자 키워드 목록입니다.
KeywordsPlus (WoS) Web of Science에서 자동으로 추출한 추가 키워드입니다. 논문의 참고문헌 제목에서 자주 등장하는 단어들로 생성됩니다.
Keywords (SCOPUS) 저자가 논문에서 직접 지정한 키워드입니다. SCOPUS에 등록된 저자 키워드 목록입니다.
KeywordsPlus (SCOPUS) SCOPUS에서 자동으로 추출하거나 추가한 색인 키워드입니다.
Language 논문이 작성된 언어입니다. 대부분 English이며, 그 외 다양한 언어로 작성된 논문이 포함될 수 있습니다.
Publication Year 논문이 출판된 연도입니다.
Publication Date 논문의 정확한 출판 날짜입니다 (년-월-일 형식).
DOI Digital Object Identifier. 디지털 객체 식별자로, 논문을 고유하게 식별하는 영구적인 식별번호입니다. 이를 통해 논문의 온라인 위치를 찾을 수 있습니다.