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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Frequency Performance Distribution Index for Short-Term System Frequency Reliability Forecast Considering Renewable Energy Integration | Risk in a power system's ability to survive imminent disturbances without recourse to low operational cost and non-interruptive energy delivery remains the responsibility of every grid operator. Intermittencies in renewable energy and dynamic load variations influence the quality of power supply. The sudden changes affect the system frequency, compromising the reliability of the system grid; generation response to frequency regulation is momentous in such an incident. Slower response or smaller reserve capacity may cause a power shortage. This paper proposes a novel predictive scheme for a short-term operational reliability evaluation for system operations planning. The proposed method evaluates the operational reliability of system frequency whiles considering high renewable power penetration and energy storage system incorporation. Required energy generations, and other grid parameters, are modelled as stochastic inputs to the framework. We formulate a reliability index as a frequency distribution considering system frequency control dynamics and processes. The IEEE Reliability Test System (RTS) is used to prove the efficacy of the proposed model. | Agyeman, Kofi Afrifa; Umezawa, Ryota; Han, Sekyung | Kyungpook Natl Univ, Elect Engn Dept, Daegu 41566, South Korea; Tokyo Inst Technol, Dept Elect Engn, Tokyo 1528550, Japan | 56925217000; 57192234496; 36023785800 | ingKofiAgyeman@gmail.com;r.umezawa.for.business@gmail.com;skhan@knu.ac.kr; | ENERGIES | ENERGIES | 1996-1073 | 13 | 11 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 0.15 | 2025-06-25 | 1 | 2 | automatic generation control; reliability index; load forecast; battery storage system; system frequency control | POWER-SYSTEMS; WIND POWER; OPERATIONAL ADEQUACY; HIGH PENETRATION; GENERATION; FARMS; MODEL | Automatic generation control; Battery storage system; Load forecast; Reliability index; System frequency control | Dynamic loads; Stochastic systems; Energy storage systems; Frequency distributions; Frequency performance; Frequency regulations; IEEE-reliability test system; Operational reliability; Quality of power supply; Renewable energy integrations; Reliability | English | 2020 | 2020-06 | 10.3390/en13112945 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Generation Capacity Expansion Planning Considering Hourly Dynamics of Renewable Resources | As more generation capacity using renewable sources is accommodated in the power system, methods to represent the uncertainty of renewable sources become more important, and stochastic models with different methods for uncertainty representation are introduced. This paper investigates the impacts of hourly variability representation of random variables on a stochastic generation capacity expansion planning model. In order to represent the hourly variability as well as uncertainty of the random parameters such as wind power availability, solar irradiance, and load, AutoRegressive-To-Anything (ARTA) stochastic process is applied. By using autocorrelations and marginal distributions of the random parameters, a stochastic process with hourly intervals is generated, where generated random sample paths are used for scenarios. A mathematical formulation using stochastic programming is presented, and a modified IEEE 300-bus system with transmission line constraints is employed to the mathematical model as a test system. Optimal generation capacity solutions obtained using GAMS/CPLEX are compared to the ones from the model only capturing the uncertainty and seasonal variability of the random parameters. The comparison results indicate that the economic value of solar photovoltaic (PV) generation may be overestimated in the case where the hourly variability is not reflected; thus, ignoring the hourly variability may lead to higher building costs and higher capacity of solar PV systems. | Park, Heejung | Kyungpook Natl Univ, Sch Energy Engn, Daegu 41556, South Korea | 56484825400 | h.park@knu.ac.kr; | ENERGIES | ENERGIES | 1996-1073 | 13 | 21 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 0.35 | 2025-06-25 | 6 | 5 | renewable energy; stochastic generation planning; power system expansion; solar PV; energy economics | VARIABILITY; SYSTEMS | Energy economics; Power system expansion; Renewable energy; Solar PV; Stochastic generation planning | Random processes; Solar buildings; Solar power generation; Stochastic programming; Stochastic systems; Wind power; Generation capacity; Marginal distribution; Mathematical formulation; Seasonal variability; Solar photovoltaics; Stochastic generation; Uncertainty representation; Wind power availability; Stochastic models | English | 2020 | 2020-11 | 10.3390/en13215626 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Hydrothermal Investigation of a Microchannel Heat Sink Using Secondary Flows in Trapezoidal and Parallel Orientations | Thermal performance enhancement in microchannel heat sinks has recently become a challenge due to advancements in modern microelectronics, which demand compatibility with heat sinks able to dissipate ever-increasing amounts of heat. Recent advancements in manufacturing techniques, such as additive manufacturing, have made the modification of the microchannel heat sink geometry possible well beyond the conventional rectangular model to improve the cooling capacity of these devices. One such modification in microchannel geometry includes the introduction of secondary flow channels in the walls between adjacent mainstream microchannels. The present study computationally models secondary flow channels in regular trapezoidal and parallel orientations for fluid circulation through the microchannel walls in a heat sink design. The heat sink is made of silicon wafer, and water is used as the circulating fluid in this study. Continuity, momentum, and energy equations are solved for the fluid flow through the regular trapezoidal secondary flow and parallel secondary flow designs in the heat sink with I-type, C-type, and Z-type inlet-outlet configurations. Plots of velocity contours show that I-type geometry creates optimal flow disruption in the heat sink. Therefore, for this design, the pressure drop and base plate temperatures are plotted for a volumetric flow rate range, and corresponding contour plots are obtained. The results are compared with corresponding trends for the conventional rectangular microchannel design, and associated trends are explained. The study suggests that the flow phenomena such as flow impingement onto the microchannel walls and formation of vortices inside the secondary flow passages coupled with an increase in heat transfer area due to secondary flow passages may significantly improve the heat sink performance. | Memon, Safi Ahmed; Cheema, Taqi Ahmad; Kim, Gyu Man; Park, Cheol Woo | Kyungpook Natl Univ, Sch Mech Engn, 80 Daehakro, Daegu 41566, South Korea; Ghulam Ishaq Khan Inst Engn Sci & Technol, Fac Mech Engn, Topi 23460, Pakistan | 58757911600; 36522492600; 55664733000; 7408416474 | safibta@gmail.com;tacheema@giki.edu.pk;gyuman.kim@knu.ac.kr;chwoopark@knu.ac.kr; | ENERGIES | ENERGIES | 1996-1073 | 13 | 21 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 0.96 | 2025-06-25 | 16 | 19 | thermal performance; microchannels; secondary flow; flow disruption | PERFORMANCE; DESIGN | Flow disruption; Microchannels; Secondary flow; Thermal performance | 3D printers; Channel flow; Geometry; Heat sinks; Heat transfer performance; Microchannels; Microelectronics; Secondary flow; Silicon wafers; Manufacturing techniques; Micro channel heat sinks; Microchannel geometries; Modern microelectronics; Parallel orientation; Rectangular microchannels; Thermal performance enhancements; Volumetric flow rate; Parallel flow | English | 2020 | 2020-11 | 10.3390/en13215616 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Potential Liquid-Organic Hydrogen Carrier (LOHC) Systems: A Review on Recent Progress | The depletion of fossil fuels and rising global warming challenges encourage to find safe and viable energy storage and delivery technologies. Hydrogen is a clean, efficient energy carrier in various mobile fuel-cell applications and owned no adverse effects on the environment and human health. However, hydrogen storage is considered a bottleneck problem for the progress of the hydrogen economy. Liquid-organic hydrogen carriers (LOHCs) are organic substances in liquid or semi-solid states that store hydrogen by catalytic hydrogenation and dehydrogenation processes over multiple cycles and may support a future hydrogen economy. Remarkably, hydrogen storage in LOHC systems has attracted dramatically more attention than conventional storage systems, such as high-pressure compression, liquefaction, and absorption/adsorption techniques. Potential LOHC media must provide fully reversible hydrogen storage via catalytic processes, thermal stability, low melting points, favorable hydrogenation thermodynamics and kinetics, large-scale availability, and compatibility with current fuel energy infrastructure to practically employ these molecules in various applications. In this review, we present various considerable aspects for the development of ideal LOHC systems. We highlight the recent progress of LOHC candidates and their catalytic approach, as well as briefly discuss the theoretical insights for understanding the reaction mechanism. | Rao, Puma Chandra; Yoon, Minyoung | Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea | RAO, PURNA CHANDRA/T-7112-2017; Rao, Purna Chandra/AHI-3532-2022 | 56378818800; 25222186500 | purna@knu.ac.kr;myyoon@knu.ac.kr; | ENERGIES | ENERGIES | 1996-1073 | 13 | 22 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 9.01 | 2025-06-25 | 250 | 255 | liquid-organic hydrogen carrier (LOHC); hydrogen storage; hydrogenation; dehydrogenation; catalyst | CATALYTIC DEHYDROGENATION; DECALIN DEHYDROGENATION; HETEROGENEOUS CATALYSIS; NITROGEN-HETEROCYCLES; CHEMICAL HYDRIDES; STORAGE; RELEASE; TOLUENE; CARBON; FUEL | Catalyst; Dehydrogenation; Hydrogen storage; Hydrogenation; Liquid-organic hydrogen carrier (LOHC) | Dehydrogenation; Fossil fuels; Fuel cells; Global warming; Hydrogen economy; Hydrogen fuels; Hydrogenation; Liquids; Thermodynamics; Bottleneck problem; Catalytic hydrogenation; Fuel cell application; High pressure compression; Organic substances; Reaction mechanism; Storage and delivery; Thermodynamics and kinetics; Hydrogen storage | English | 2020 | 2020-11 | 10.3390/en13226040 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Statistical Methodology for the Definition of Standard Model for Energy Analysis of Residential Buildings in Korea | This study was conducted to propose an optimal methodology for deriving a standard model from existing residential buildings. To strategically improve existing residential buildings, it is necessary to identify standard models that can be used as quantitative standards. In this study, a total of six methods were established for different algorithms in the dimensionality reduction and clustering stage of the data preprocessing stage. In addition, a total of 22,342 households' data were analyzed, and a total of 26 variables were used to perform cluster analysis. The process of method 6 (data pre-processing, principal components analysis, clustering [K-medoids], verification) was proposed as a way to derive the standard model from the existing Korean housing. The method proposed in this study is capable of deriving a number of standard models considering all variables (n) in a single analysis. The representative building derived in this study contains a lot of building data, so it can be effectively used for planning and research related to buildings on a regional and national scale. In addition, this process can be applied to various buildings to derive representative buildings. | Nam, Hye-Ryeong; Kim, Seo-Hoon; Han, Seol-Yee; Lee, Sung-Jin; Hong, Won-Hwa; Kim, Jong-Hun | Korea Inst Energy Res, Energy ICT Convergence Res Dept, Daejeon 34101, South Korea; Kyungpook Natl Univ, Sch Architectural Civil Environm & Energy Engn, 80 Daehak Ro, Daegu 41566, South Korea | 57224678166; 57201465295; 57208553554; 57194414378; 7401527968; 57214338689 | nhryeong@kier.re.kr;takesky@kier.re.kr;syhan@kier.re.kr;sjleeki@kier.re.kr;hongwonhwa@gmail.com;jonghun@kier.re.kr; | ENERGIES | ENERGIES | 1996-1073 | 13 | 21 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 0.15 | 2025-06-25 | 2 | 2 | standard model; representative building; clustering; energy retrofit | RETROFIT | Clustering; Energy retrofit; Representative building; Standard model | Cluster analysis; Dimensionality reduction; Data preprocessing; Energy analysis; Existing residential buildings; Principal components analysis; Quantitative standards; Residential building; Statistical methodologies; The standard model; Housing | English | 2020 | 2020-11 | 10.3390/en13215796 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | Study on the correlation between partial discharge energy and SF6 decomposition gas generation | In this paper, the amount of SF6 decomposition gases due to the partial discharge (PD) was studied in the SF6 gas-insulated transformer. The long-term PD degradation experiment was performed while controlling the discharge magnitude using the surface discharge, and the gas generation amount was measured by using gas chromatography for SO2F2, SOF2, SO2, CO, and CF4. In addition, to investigate the relationship between the partial discharge energy and the decomposed gas generation amount, partial discharge energy was calculated by a data processing program and converted to the unit of joule per mole. With the finite element method (FEM), the electric field distribution and SF6 gas decomposition mechanism were explained for the partial discharge energy effect on the gas generation. This study helps understand the relationship between the partial discharge energy and the decomposed gas generation ratio with the experimental results and can be used for the diagnosis of PD and maintenance process for the gas-insulated transformers. © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | Cho, Yong Sung; Hong, Tae Yoon; Youn, Young Woo; Sun, Jong Ho; Lee, Se-Hee | Advanced Power Apparatus Research Center, Korea Electrotechnology Research Institute (KERI), Changwon, 51543, South Korea, Laboratory for Electromagnetic Multiphysics, Kyungpook National University (KNU), Daegu, 41566, South Korea; Advanced Power Apparatus Research Center, Korea Electrotechnology Research Institute (KERI), Changwon, 51543, South Korea; Advanced Power Apparatus Research Center, Korea Electrotechnology Research Institute (KERI), Changwon, 51543, South Korea; Advanced Power Apparatus Research Center, Korea Electrotechnology Research Institute (KERI), Changwon, 51543, South Korea; Laboratory for Electromagnetic Multiphysics, Kyungpook National University (KNU), Daegu, 41566, South Korea | 55472200200; 57218937685; 24825813000; 56115744900; 55009905600 | shlees@knu.ac.kr; | Energies | ENERGIES | N/A | 1996-1073 | 13 | 18 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 0.51 | 2025-06-25 | 11 | Decomposed components; Gas chromatography; Gas-insulated transformer; Partial discharge energy | Data handling; Decomposition; Gas chromatography; Gas generators; Gases; Partial discharges; Sulfur dioxide; Sulfur hexafluoride; Decomposed gas; Decomposition gas; Discharge energy; Discharge magnitude; Electric field distributions; Gas generation; Gas-insulated transformers; Maintenance process; SF6 insulation | English | Final | 2020 | 10.3390/en13184655 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Thermal Comfort in the Passenger Compartment Using a 3-D Numerical Analysis and Comparison with Fanger's Comfort Models | The paper presents the human thermal comfort inside a car cabin using three-dimensional numerical analysis and state of the art comfort models. Vehicular thermal comfort is a must concern factor in modern car manufacturing industries. Numerical simulations have been performed to accurately predict the temperature inside the car cabin and velocity of airflow. The numerical results are then compared using Fanger's model, the equivalent temperature model and the modified Fanger's model. A link has been developed using a general thermal comfort index for the considered human thermal comfort models. The general thermal comfort index takes into consideration all the investigated parameters that affect the vehicular thermal comfort thereby evaluating the whole car environment. The thermally comfortable conditions for the driver and passengers in a vehicular cabin are also addressed based on some of the thermal comfort indexes available in literature. In addition, the solar load has also been added using a surface radiation model to consider the environmental heat load effect on cabin thermal comfort. | Khatoon, Saboora; Kim, Man-Hoe | Kyungpook Natl Univ, Sch Mech Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, IEDT, Daegu 41566, South Korea | 57197833125; 55686310000 | saboorakhatoon@yahoo.com;manhoe.kim@knu.ac.kr; | ENERGIES | ENERGIES | 1996-1073 | 13 | 3 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 1.73 | 2025-06-25 | 34 | 41 | human thermal comfort; car ventilation; solar load; Fanger's model; equivalent temperature; computational fluid dynamics | TEMPERATURE CONTROL; RELATIVE-HUMIDITY; SOLAR-RADIATION; AIR-FLOW; CABIN; ENVIRONMENT; SENSATION; SYSTEM; STATE | Car ventilation; Computational fluid dynamics; Equivalent temperature; Fanger's model; Human thermal comfort; Solar load | Air; Computational fluid dynamics; Numerical analysis; Thermal comfort; 3-D numerical analysis; Equivalent temperature; Human thermal comfort; Passenger compartment; Solar load; Surface radiation models; Thermal comfort index; Three-dimensional numerical analysis; Numerical models | English | 2020 | 2020-02 | 10.3390/en13030690 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Volume and Surface Resistivity Measurement of Insulating Materials Using Guard-Ring Terminal Electrodes | Recently, eco-friendly energy conversion policies have been being promoted through de-nuclearization and de-coal. For this purpose, a super grid should be built to optimize sustainable renewable energy resources such as solar and wind power. Accordingly, considering the various problems such as technology and cost, a system for efficient energy transmission is required. Hence, research is being actively conducted to apply it, owing to the development of the high voltage direct current (HVDC) system. Among HVDC systems, the cable system is extremely important, in addition to the measurement of the dielectric breakdown strength, space charge, and volume resistivity of insulating materials. The existing resistivity measurement method measures both the volume and surface resistivity using a three-terminal electrode that is used in the international standards of American Society for Testing and Materials (ASTM) D 257 and International Electrotechnical Commission (IEC) 60093. However, the circuit configuration differs depending on the measurement of the volume and surface resistivity; moreover, when a DC voltage is applied to the insulator, a charging current flows and there are multiple samples to be measured, which takes a considerable amount of time. Therefore, in this study, we proposed a new type of resistivity measurement system that is based on the existing three-terminal electrode system. Furthermore, we produced a system capable of simultaneously measuring the volume and surface resistivity. Finally, using this system, we compared and analyzed the volume and surface resistivity of five insulating materials. | Lee, Heon-Gyeong; Kim, Jin-Gyu | Kyungpook Natl Univ, Dept Elect Engn, High Voltage & Plasma Applicat Lab HVPAL, Daegu 41566, South Korea | 57210461319; 54680957000 | hglee0211@knu.ac.kr;kjg@knu.ac.kr; | ENERGIES | ENERGIES | 1996-1073 | 13 | 11 | SCIE | ENERGY & FUELS | 2020 | 3.004 | 61.0 | 0.49 | 2025-06-25 | 13 | 13 | volume resistivity; surface resistivity; leakage current | Leakage current; Surface resistivity; Volume resistivity | Coal industry; Dielectric materials; Electric breakdown; Electrodes; Energy conversion; Insulating materials; Insulation; Wind power; American society for testing and materials; Circuit configurations; Dielectric breakdown strength; High voltage direct current; International Electrotechnical Commission; International standards; Resistivity measurement; Three terminal electrodes; HVDC power transmission | English | 2020 | 2020-06 | 10.3390/en13112811 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | White blood cell labeling with Technetium-99m (⁹⁹mTc) using red blood cell extracellular vesicles-mimetics | Background: Extracellular vesicles, have gained increasing attention for their application in drug delivery. Here, we developed a novel method for radiolabeling WBCs with Tc-99m using RBC-derived extracellular vesicles-mimetics (EVMs), and monitored in vivo inflammation tracking of Tc-99m-WBC using gamma camera in acute inflammation mouse model. Methods: Engineered EVMs from RBCs were produced by a one-step extrusion method. RBC-EVMs were analyzed by NTA and TEM. Cells were labeled with Tc-99m by using Tc-99m-RBC-EVMs. Inflammation mice model was prepared and confirmed by F-18-FDG PET/CT. Tc-99m-WBCs were injected in mice, and their biodistribution was analyzed by gamma camera. Finding: The radiochemical purity of Tc-99m-RBC-EVMs was 100%. The Tc-99m-labeling din affect the size and morphology. The Tc-99m in the cytoplasm of RBC-EVMs was successfully confirmed by high angle annular dark field STEM (scanning transmission electron microscope). Cells were successfully labeled with Tc-99m using Tc-99m-RBC-EVMs, and the counts per minute was increased in dose- and time-dependent manners. The F-18-FDG PET/CT images confirmed establishment of acute inflammation (left mouse foot). Tc-99m-WBCs showed higher uptake in the inflamed foot than non-inflamed foot. Interpretation: This novel method for radiolabeling WBCs using RBC-EVMs. Tc-99m labeling may be a feasible method to monitor the in vivo biodistribution of cells. | Son, Seung Hyun; Oh, Ji Min; Gangadaran, Prakash; Ji, Hyun Dong; Lee, Ho Won; Rajendran, Ramya Lakshmi; Baek, Se Hwan; Gopal, Arunnehru; Kalimuthu, Senthilkumar; Jeong, Shin Young; Lee, Sang-Woo; Lee, Jaetae; Ahn, Byeong-Cheol | Kyungpook Natl Univ, Sch Med, Dept Nucl Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Nucl Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu, South Korea | ; Gangadaran, Prakash/AAV-3102-2021; Rajendran, Ramya/AAV-6338-2021; Lee, Jaetae/AAR-3317-2021; lee, sangwoo/KUD-1906-2024 | 56596907400; 57190370462; 54393130400; 57191592819; 35337240700; 57195318729; 57194785139; 57203278478; 54794141400; 36164032500; 57196249819; 7601451907; 7202791511 | abc2000@knu.ac.kr; | BLOOD CELLS MOLECULES AND DISEASES | BLOOD CELL MOL DIS | 1079-9796 | 1096-0961 | 80 | SCIE | HEMATOLOGY | 2020 | 3.039 | 61.2 | 0.99 | 2025-06-25 | 17 | 18 | Inflammation; White blood cell; Technetium-99m; Gamma camera; Red blood cell; Extracellular vesicles-mimetics | DRUG-DELIVERY; EXOSOMES; INFLAMMATION; NANOVESICLES; LEUKOCYTES; IN-111; HMPAO; ACID | Extracellular vesicles-mimetics; Gamma camera; Inflammation; Red blood cell; Technetium-99m; White blood cell | Animals; Cell Tracking; Disease Models, Animal; Erythrocytes; Extracellular Vesicles; Female; Inflammation; Leukocytes; Mice; Molecular Imaging; Radiopharmaceuticals; Rats; Staining and Labeling; Subcellular Fractions; Technetium; Tissue Distribution; fluorodeoxyglucose f 18; technetium 99m; radiopharmaceutical agent; technetium; animal cell; animal experiment; animal model; animal tissue; Article; biological monitoring; cell engineering; cell labeling; cellular distribution; controlled study; cytoplasm; drug distribution; drug purity; erythrocyte; erythrocyte structure; exosome; female; foot disease; in vivo study; inflammation; isotope labeling; leukocyte; mouse; nonhuman; positron emission tomography-computed tomography; priority journal; radiochemistry; rat; scanning electron microscopy; scanning transmission electron microscopy; time factor; animal; cell fractionation; cell tracking; diagnostic imaging; disease model; erythrocyte; exosome; inflammation; leukocyte; metabolism; molecular imaging; procedures; staining; tissue distribution; ultrastructure | English | 2020 | 2020-02 | 10.1016/j.bcmd.2019.102375 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | In-situ analysis of the hydration ability of bone graft material using a synchrotron radiation X-ray micro-CT | The conventional micro-computed tomography (mu CT) is a non-destructive imaging technique used for obtaining 2D and 3D information for scaffolds. The main composition and internal structure are important in mimicking and designing the characteristics of natural bone. This study was three-dimensional evaluating the external or internal structures and the hydration effects of bone graft materials by using the in-situ image technique. Synchrotron radiation micro-computed tomography (SR-mu CT) was used to extract information on the geometry of two biphasic calcium phosphates (BCP) with identical chemicals and different micro-macro porosity, pore size distribution, and pore interconnection pathways. Volume analysis by hydration was used to measure the two bone graft materials at 0, 5, and 10-min intervals. The SR-mu CT image was achieved with information regarding the internal pore structure and hydration effects evaluated under 3D visualization. Both types of bone graft materials showed structures suitable for tissue engineering applications. The SR-mu CT in-situ techniques with 3D information provided a detailed view of the structures. Thus, SR-mu CT could be an available, unbiased 3D alternative to in-situ analysis. | Seo, Seung-Jun; Kim, Yong-Gun | Kyungpook Natl Univ, Sch Dent, Dept Periodontol, A3DI, Daegu, South Korea; Kyungpook Natl Univ, Inst Translat Res Dent, Daegu, South Korea | 59056013900; 55622694400 | periokyg@knu.ac.kr; | JOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALS | J APPL BIOMATER FUNC | 2280-8000 | 18 | SCIE | BIOPHYSICS;ENGINEERING, BIOMEDICAL;MATERIALS SCIENCE, BIOMATERIALS | 2020 | 2.604 | 61.3 | 0.47 | 2025-06-25 | 8 | 9 | In-situ analysis; hydration effect; bone graft material; synchrotron radiation X-ray micro-CT | SCAFFOLDS; REGENERATION; POROSITY | bone graft material; hydration effect; In-situ analysis; synchrotron radiation X-ray micro-CT | Bone and Bones; Porosity; Synchrotrons; Tissue Engineering; X-Ray Microtomography; Calcium phosphate; Computerized tomography; Hydration; Pore size; Pore structure; Synchrotrons; Three dimensional computer graphics; Tissue; Tissue engineering; calcium phosphate; 3D information; Bone graft materials; Composition structure; Hydration effects; In-situ analysis; Internal structure; Natural bone; Non-destructive imaging; Synchrotron radiation X-ray micro-CT; X-ray micro-CT; Article; bone graft; controlled study; geometry; hydration; micro-computed tomography; pore size distribution; porosity; surface property; synchrotron radiation micro-computed tomography; three-dimensional imaging; bone; diagnostic imaging; micro-computed tomography; synchrotron; tissue engineering; Synchrotron radiation | English | 2020 | 2020-12 | 10.1177/2280800020963476 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Hepatic protective effects of sulforaphane through the modulation of inflammatory pathways | The aim of this study was to investigate the effects of sulforaphane (SFN) on lipopolysaccharide (LPS)-induced liver failure, and to elucidate underlying mechanisms. SFN, a natural isothiocyanate present in cruciferous vegetables such as broccoli and cabbage, is effective in preventing carcinogenesis, diabetes, and inflammatory responses. Mice were treated intravenously with SFN at 12 h after LPS treatment. LPS significantly increased mortality, serum levels of liver damage markers, and inflammatory cytokines, and toll-like receptor 4 (TLR4) protein expression, which were reduced by SFN. Our results suggest that SFN protects against LPS-induced liver damage, indicating its potential to treat liver diseases. | Lee, Changhun; Yang, Sumin; Lee, Bong-Seon; Jeong, So Yeon; Kim, Kyung-Min; Ku, Sae-Kwang; Bae, Jong-Sup | Kyungpook Natl Univ, Coll Pharm, CMRI, Res Inst Pharmaceut Sci,Plus KNU Multiom Based Cr, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Appl BioSci, Div Plant Biosci, Daegu 41566, South Korea; Daegu Haany Univ, Coll Korean Med, Dept Anat & Histol, 1 Haanydaero, Gyongsan 38610, South Korea | Bae, Jong-Sup/AAU-9724-2020; Kim, Kyung-Min Kim/C-7007-2014 | 59109211900; 57204186412; 57204178543; 58443839300; 34868260300; 7006331005; 16021543200 | gucci200@hanmail.net;baejs@knu.ac.kr; | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | J ASIAN NAT PROD RES | 1028-6020 | 1477-2213 | 22 | 4 | SCIE | CHEMISTRY, APPLIED;CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY;PLANT SCIENCES | 2020 | 1.571 | 61.5 | 0.45 | 2025-06-25 | 11 | 10 | Sulforaphane; liver failure; inflammation; toll-like receptor; lipopolysaccharide | TOLL-LIKE RECEPTORS; KAPPA-B; FAILURE; INJURY; LIVER | inflammation; lipopolysaccharide; liver failure; Sulforaphane; toll-like receptor | Animals; Isothiocyanates; Lipopolysaccharides; Liver; Mice; Molecular Structure; alanine aminotransferase; aspartate aminotransferase; beta interferon; I kappa B kinase alpha; immunoglobulin enhancer binding protein; interleukin 6; lamin B; lamin B1; mitogen activated protein kinase; mitogen activated protein kinase p38; myeloid differentiation factor 88; protein c jun; stress activated protein kinase; sulforaphane; toll like receptor 4; toll like receptor adaptor molecule 1; tumor necrosis factor; unclassified drug; isothiocyanic acid derivative; lipopolysaccharide; sulforafan; alanine aminotransferase blood level; animal experiment; animal model; animal tissue; antiinflammatory activity; Article; aspartate aminotransferase blood level; cell viability; controlled study; cytokine production; drug effect; drug mechanism; hepatitis; human; human cell; lipopolysaccharide-induced liver injury; liver failure; liver histology; liver protection; male; mouse; nonhuman; protein blood level; protein expression; signal transduction; survival analysis; animal; chemical structure; liver | English | 2020 | 2020-04-02 | 10.1080/10286020.2019.1581174 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Relative Survival Benefit by Hormonal Receptor Status of Adding Trastuzumab to Neoadjuvant Chemotherapy in Breast Cancer Patients | Purpose: Neoadjuvant chemotherapy (NAC) involving trastuzumab markedly increases pathologic complete response (pCR) rates in patients with human epidermal growth factor receptor 2-positive (HER2+) breast cancer. Despite increasing pCR rates, long-term survival gains are controversial owing to distinctive biologic behavior mediated by the presence of hormonal receptors (HRs) that may interact with HER2 receptors. We, therefore, investigated the differences in relative survival gain provided by neoadjuvant trastuzumab-based chemotherapy on HR positive (HR+) status of patients. Methods: We retrospectively ana Patient clinical characteristics were compared usin lyzed women with stage II or III HER2+ breast cancer who underwent NAC followed by a breast cancer surgery between 2008 and 2013. The survival benefits of adding trastuzumab to NAC were analyzed by classifying patients into HR+ and HR negative (HR-) groups. Results: Of 666 patients included in the study, 374 (52.1%) were HR+ and 319 (47.9%) were HR-. In the HR+ group, trastuzumab treatment led to higher pCR rates and significantly better breast cancer specific survival (BCSS) and overall survival (OS) than no trastuzumab treatment. However, among patients with HR- breast cancer, trastuzumab treatment showed no statistically significant difference between BCSS and OS following multivariate analysis. Conclusion: We found that the addition of trastuzumab to NAC improved relative survival benefit in HER2+/HR+ patients than in HER2+/HR- patients, even though the pCR rate increases were lower. Although pCR has been regarded as a surrogate marker for estimating long-term survival benefits after NAC, it alone may not translate into real long-term oncologic outcomes in particular cancer subtypes after trastuzumab-based NAC. Further longer-term evaluation of the objective survival benefit after NAC driven by a dual HER2 block according to HR status is warranted. | Schneider, Jean; Lee, Hyouk Jin; Nam, Seok Jin; Lee, Soo Jung; Jung, Jin Hyang; Jung, Sung Hoo; Lim, Seung Taek; Jeon, Ye Won; Gwak, Hongki | Univ Texas Austin, Coll Nat Sci, Austin, TX 78712 USA; Segyero Hosp, Busan, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Surg, Div Breast Surg,Sch Med, Seoul, South Korea; Yeungnam Univ Hosp, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Dept Surg, Sch Med, Daegu, South Korea; Jeonbuk Natl Univ, Dept Surg, Med Sch, Jeonju, South Korea; Catholic Univ Korea, St Vincents Hosp, Coll Med, Dept Surg,Div Breast & Thyroid Surg Oncol, 93 Jungbu Daero, Suwon 16247, South Korea | ; Park, Jin-Hong/F-1829-2014; gwak, hongki/HGB-1082-2022; Lee, Jong-Mok/KVY-9550-2024 | 57209803125; 56709043900; 7402276023; 57203597252; 57209310173; 24171343100; 57203787062; 57199705020; 57201058931 | hkgwak@gmail.com; | JOURNAL OF BREAST CANCER | J BREAST CANCER | 1738-6756 | 2092-9900 | 23 | 3 | SCIE | ONCOLOGY | 2020 | 3.588 | 61.8 | 0.2 | 2025-06-25 | 4 | 5 | Breast neoplasms; Induction chemotherapy; Receptor; ErbB-2; Survival; Trastuzumab | PATHOLOGICAL COMPLETE RESPONSE; LONG-TERM OUTCOMES; CELL LUNG-CANCER; ASIAN PATIENTS; TRIAL; THERAPY; HER2; ASSOCIATION; EXPRESSION | Breast neoplasms; Induction chemotherapy; Receptor, ErbB-2; Survival; Trastuzumab | epidermal growth factor receptor; epidermal growth factor receptor 2; hormone receptor; trastuzumab; adult; aged; Article; breast cancer molecular subtype; cancer adjuvant therapy; cancer hormone therapy; cancer prognosis; cancer specific survival; cancer staging; cancer surgery; clinical outcome; clinical trial; controlled clinical trial; controlled study; disease free survival; disease marker; female; follow up; gene overexpression; human; human tissue; immunohistochemistry; long term survival; major clinical study; mastectomy; middle aged; neoadjuvant chemotherapy; overall survival; partial mastectomy; retrospective study; survival analysis; very elderly; young adult | English | 2020 | 2020-06 | 10.4048/jbc.2020.23.e34 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | The Therapeutic Effect of Cyclin-Dependent Kinase 4/6 Inhibitor on Relapsed Ectopic Male Breast Cancer | Ectopic male breast cancer is very rare. Consequently, there is a lack of prospective clinical trials, and most recommendations for treatment are based on the experiences of clinicians and data from female breast cancer patients. The United States Food and Drug Administration has recently approved palbociclib combined with endocrine therapy for advanced male breast cancer because of the positive results of its use in metastatic female breast cancer. Therefore, it is worth considering cyclin-dependent kinase 4/6 inhibitors as alternatives to conventional chemotherapies for advanced male breast cancer patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative cancers. The present case report introduces the use of palbociclib plus letrozole as first-line therapy for an elderly male patient with relapsed ectopic breast cancer, notwithstanding the limitations of the current national health insurance policy. | Baek, Dong Won; Park, Jee Young; Lee, Soo Jung; Chae, Yee Soo | Kyungpook Natl Univ, Canc Res Inst, Dept Oncol Hematol, Chilgok Hosp,Sch Med, 807 Hoguk Ro, Daegu 41404, South Korea; Kyungpook Natl Univ, Canc Res Inst, Dept Pathol, Chilgok Hosp,Sch Med, 807 Hoguk Ro, Daegu 41404, South Korea | Park, Jung Hwan/AAA-1951-2022 | 57191874272; 57226185359; 57203597252; 57190793908 | yschae@knu.ac.kr; | JOURNAL OF BREAST CANCER | J BREAST CANCER | 1738-6756 | 2092-9900 | 23 | 5 | SCIE | ONCOLOGY | 2020 | 3.588 | 61.8 | 0 | 2025-06-25 | 1 | 1 | Breast neoplasms; Male; Palbociclib | PALBOCICLIB; LETROZOLE | Breast neoplasms; Male; Palbociclib | BRCA2 protein; cyclin dependent kinase inhibitor; cyclophosphamide; doxorubicin; epidermal growth factor receptor 2; estrogen receptor; goserelin; letrozole; paclitaxel; palbociclib; progesterone receptor; tamoxifen; aged; Article; case report; clinical article; human; human tissue; male; male breast cancer; positron emission tomography-computed tomography | English | 2020 | 2020-10 | 10.4048/jbc.2020.23.e39 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Discovery, Crystal Growth, and Scintillation Properties of Novel Tl-Based Scintillators | Pioneered by our group, thallium (Tl)-based inorganic halide single-crystals are potential new scintillators. Most of these scintillators exhibit excellent scintillation performance, including peak emission between 370 and 450 nm, good energy resolutions, high light yield (more than 50 000 ph MeV-1) and fast decay-time (less than 40 ns). In addition, these scintillators demonstrate good pulse shape discrimination capability. The grown pure crystals show strong luminescence and high light yields due to the presence of Tl ion in the host lattice. Thanks to the high Z-number and density of the Tl, the grown scintillators have high density (rho > 4 g cm(-3)) and high effective Z-number (Z(eff) >= 60). Being hygroscopic, like other halide scintillators, these single crystals are grown by the Bridgman technique. It is expected that the discovered scintillators will perform better than most commercial scintillators used in different applications. Significant improvement in the scintillation properties are achieved with the modification of the crystal growth procedure of the grown scintillators. Preliminary results revealed that these scintillators are very promising from an application point of view, while further investigations are underway for the enhancement of the present scintillators as well as for the discovery of new compounds of this family. | Kim, HongJoo; Rooh, Gul; Khan, Arshad; Vuong, Phan Quoc; Kim, Sunghwan | Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Abdul Wali Khan Univ, Dept Phys, Mardan 23200, Pakistan; Cheongju Univ, Dept Radiol Sci, Cheongju 41566, South Korea | Rooh, Gul/AAF-2076-2019; Kim, Hong Joo/AAE-1178-2022; Khan, Arshad/ABB-1566-2021 | 59051568100; 24401665700; 56017063700; 57207618553; 36165569900 | hongjoo@knu.ac.kr; | CRYSTAL RESEARCH AND TECHNOLOGY | CRYST RES TECHNOL | 0232-1300 | 1521-4079 | 55 | 10 | SCIE | CRYSTALLOGRAPHY | 2020 | 1.639 | 62.0 | 0.26 | 2025-06-25 | 5 | 5 | Bridgman method; luminescence; scintillation light yield | PULSE-SHAPE DISCRIMINATION; CE3+; LUMINESCENCE; RAY | Bridgman method; luminescence; scintillation light yield | Crystal growth; Crystallization; Light; Scintillation; Scintillation counters; Single crystals; Thallium compounds; Bridgman techniques; Energy resolutions; Inorganic halides; Peak emissions; Pulse shape discrimination; Scintillation performance; Scintillation properties; Strong luminescence; Ionization | English | 2020 | 2020-10 | 10.1002/crat.202000074 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Ascending projection of jaw-closing muscle-proprioception to the intralaminar thalamic nuclei in rats | An invasive intralaminar thalamic stimulation and a non-invasive application of oral splint are both effective in treating tic symptoms of patients with Tourette syndrome (TS). Therefore, these two treatments may exert some influence on the same brain region in TS patients. We thus hypothesized that the proprioceptive input arising from the muscle spindles of jaw-closing muscles (JCMSs), known to be increased by the application of oral splint, is transmitted to the intralaminar thalamic nuclei. To test this issue, we morphologically and electrophysiologically examined the thalamic projections of proprioceptive input from the JCMSs to the intralaminar thalamic nuclei of rats. We first injected an anterograde tracer, biotinylated dextranamine, into the electrophysiologically identified supratrigeminal nucleus, which is known to receive proprioceptive inputs from the JCMSs via the trigeminal mesencephalic neurons. A moderate number of biotinylated dextranamine-labeled axon terminals were bilaterally distributed in the oval paracentral nucleus (OPC) of the intralaminar thalamic nuclei. We also detected electrophysiological responses to the electrical stimulation of bilateral masseter nerves and to sustained jaw-opening in the OPC. After injection of retrograde tracer (cholera toxin B subunit or Fluorogold) into the OPC, neuronal cell bodies were retrogradely labeled in the rostrodorsal portion of the bilateral supratrigeminal nucleus. Here, we show that proprioceptive inputs from the JCMSs are conveyed to the OPC in the intralaminar nuclei via the supratrigeminal nucleus. This study can help to understand previously unrecognized pathways of proprioception ascending inputs from the brainstem to the thalamus, which may contribute to treatments of TS patients. | Sato, Fumihiko; Kado, Seiya; Tsutsumi, Yumi; Tachibana, Yoshihisa; Ikenoue, Etsuko; Furuta, Takahiro; Uchino, Katsuro; Bae, Yong Chul; Uzawa, Narikazu; Yoshida, Atsushi | Osaka Univ, Grad Sch Dent, Dept Oral Anat & Neurobiol, 1-8 Yamadaoka, Suita, Osaka 5650871, Japan; Osaka Univ, Grad Sch Dent, Dept Oral & Maxillofacial Surg 2, Suita, Osaka 5650871, Japan; Kobe Univ, Div Syst Neurosci, Grad Sch Med, Kobe, Hyogo 6500017, Japan; Takarazuka Univ Med & Hlth Care, Dept Acupuncture, Takarazuka, Hyogo 6660162, Japan; Kyungpook Natl Univ, Sch Dent, Dept Anat & Neurobiol, Daegu 700412, South Korea | 37112998700; 57216320819; 57196150893; 47461520500; 57185769100; 7201372674; 35742156800; 56377838800; 6603144046; 55757780066 | yoshida@dent.osaka-u.ac.jp; | BRAIN RESEARCH | BRAIN RES | 0006-8993 | 1872-6240 | 1739 | SCIE | NEUROSCIENCES | 2020 | 3.252 | 62.1 | 0.39 | 2025-06-25 | 8 | 7 | Deep sensation; Muscle spindle; Supratrigeminal nucleus; Thalamus; Tourette syndrome; Deep brain stimulation | MESENCEPHALIC TRIGEMINAL NEURONS; DEEP BRAIN-STIMULATION; PARABRACHIAL NUCLEUS; MIDLINE; PATHWAYS; TRACT | Deep brain stimulation; Deep sensation; Muscle spindle; Supratrigeminal nucleus; Thalamus; Tourette syndrome | Animals; Brain; Brain Mapping; Brain Stem; Cerebral Cortex; Disease Models, Animal; Intralaminar Thalamic Nuclei; Jaw; Male; Muscle Spindles; Muscle, Skeletal; Neural Pathways; Neurons; Proprioception; Rats; Rats, Wistar; Thalamic Nuclei; Tourette Syndrome; Trigeminal Nuclei; cholera toxin B subunit; dextranamine; fluorogold; tracer; unclassified drug; animal experiment; Article; biotinylation; brain nucleus; brain stem; electrophysiological procedures; electrostimulation; Gilles de la Tourette syndrome; jaw closing muscle spindle; male; muscle spindle; nerve ending; nonhuman; oval paracentral nucleus; priority journal; proprioception; rat; supratrigeminal nucleus; thalamus intralaminar nucleus; trigeminal nucleus; animal; brain; brain cortex; brain mapping; disease model; innervation; jaw; muscle spindle; nerve cell; nerve tract; pathophysiology; physiology; procedures; proprioception; skeletal muscle; thalamus intralaminar nucleus; thalamus nucleus; Wistar rat | English | 2020 | 2020-07-15 | 10.1016/j.brainres.2020.146830 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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