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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Article | Effect of glycerol addition time on the cryopreserved Korean native brindle cattle (Chikso) sperm quality | Although cryopreservation is an efficient method for maintaining the biological and genetic resources of sperm, the sperm damage during the cryopreservation process cannot be ignored. It should be possible to obtain the most effective cryopreservation performance by accurately grasping the effects of various factors on the cryopreservation of sperm. The previous study demonstrated that a suitable standard protocol for cryopreservation of Korean native brindled cattle (Chikso) does not exist, based on the methods for semen cryopreservation of Chikso differ in each research center. The most obvious difference between most of protocols is the addition of glycerol before and after cooling during the Chikso cryopreserved semen process. Therefore we focused on the effects of glycerol addition time on the quality of cryopreserved Chikso sperm. In the present study, 27 individual Chikso samples were collected by transrectal massage and divided into two parts: the "cryopreservation method A" group (adding glycerol before cooling) and the "cryopreservation method B" group (adding glycerol after cooling). Meanwhile, the values of various sperm parameters were derived from each group, including sperm motility, kinematics, capacitation status, cell viability, and intracellular ATP levels, which we used to compare and evaluate sperm function. The results of this study indicated that during the semen cryopreservation process of the Chikso, the addition of glycerol after cooling yielded superior results in a variety of sperm parameters, such as sperm motility, progressive motility, rapid motility, VCL, VSL, VAP, ALH, capacitation status, viability, and intracellular ATP level after freezing and thawing. Our study is suggested that the glycerol addition time during the cryopreservation process for Chikso should be considered. In addition, our results may be provided reference to develop suitable the cryopreservation procedure of the Chikso sperm. | Ma, Lei; Kim, Dae-Hyun; Jung, Eun-Ju; Lee, Woo-Jin; Hwang, Ju-Mi; Bae, Jeong-Won; Jung, Dae-Jin; Yi, Jun Koo; Lee, Sang Moo; Ha, Jae Jung; Kwon, Woo-Sung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju, Gyeongsangbuk D, South Korea; Gyeongbuk Livestock Res Inst, Yeongju, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Dept Anim Biotechnol, Sangju, Gyeongsangbuk D, South Korea | Bae, Jeong-Won/AAH-4932-2021; Kwon, Woo-Sung/J-6731-2019; Yi, Junkoo/JBR-8507-2023 | hjjggo@korea.kr;wskwon@knu.ac.kr; | ANIMAL REPRODUCTION | ANIM REPROD | 1806-9614 | 1984-3143 | 19 | 1 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | 2022 | 1.7 | 52.4 | 1 | cryopreservation; glycerol adding time; Korean native brindle cattle (Chikso); Sperm functions | FATTY-ACID-COMPOSITION; COLD SHOCK INJURY; POSTTHAW QUALITY; FERTILITY; RECOVERY; MOTILITY | English | 2022 | 2022 | 10.1590/1984-3143-ar2021-00581/12 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Evaluation of alumina slurry dispersion by nuclear magnetic resonance relaxation as a comparison to conventional dispersion evaluation methods | In this paper, we evaluated the particle dispersion degree of alumina slurry containing a dispersant by solvent nuclear magnetic resonance (NMR) relaxation and compared it with conventional dispersion evaluation methods such as viscosity, particle size, and sedimentation height measurements. The dispersion of slurry was evaluated via numerical analysis of the transverse relaxation time (T-2). The effect of the changes in different parameters of the experiment in terms of milling time, solid loading, and dispersant amount was investigated by NMR relaxation as well as conventional methods. The results of NMR relaxation measurements revealed that T-2 correlates well with other dispersion evaluation methods; thus, it is an efficient technique to evaluate the dispersion of alumina slurry, specifically, when studying the effect of the change in milling time and dispersion amount. | Shakirbay, Akerke; Choi, Jeong Sik; Kim, Dong Chul; Shin, Hyo Soon; Yeo, Dong Hun; Lee, Joon Hyung | Korea Inst Ceram Engn & Technol, Elect Convergence Mat Div, 101 Sohoro, Jinju, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu, South Korea | 57737551300; 57737693000; 57226389154; 35273922400; 7006551146; 57204923460 | hsin@kicet.re.kr; | MAGNETIC RESONANCE IN CHEMISTRY | MAGN RESON CHEM | 0749-1581 | 1097-458X | 60 | 9 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;CHEMISTRY, PHYSICAL;SPECTROSCOPY | 2022 | 2 | 52.4 | 0.19 | 2025-06-25 | 2 | 3 | alumina slurry; dispersion evaluation method; NMR relaxation | NMR SOLVENT RELAXATION; POLYMER; OPTIMIZATION; ADSORPTION; SILICA | alumina slurry; dispersion evaluation method; NMR relaxation | Alumina; Aluminum oxide; Dispersions; Milling (machining); Particle size; Particle size analysis; Petroleum reservoir evaluation; Alumina slurry; Dispersants; Dispersion degree; Dispersion evaluation method; Evaluation methods; Magnetic resonance relaxation; Milling time; Nuclear magnetic resonance relaxation; Particle dispersion; Particles sizes; Nuclear magnetic resonance | English | 2022 | 2022-09 | 10.1002/mrc.5291 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Long-Term Survival Rate of Autogenous Tooth Transplantation: Up to 162 Months | Background and Objectives: The purpose of this study is to observe the usefulness of autogenous tooth transplantation by examining the cumulative survival rate according to the period of auto-transplanted teeth as pre-implant treatment. Materials and Methods: This study was conducted on 111 patients who visited Kyungpook National University Dental Hospital and underwent autogenous tooth transplantation between November 2008 and January 2021 (about 13 years). The cumulative survival rate of autogenous tooth transplantation according to the causes of extraction of the recipient tooth (caries, periapical lesion, crack, crown fracture, periodontitis) and condition of opposing teeth (natural teeth vs. fixed prosthesis). The cumulative survival rate of autogenous tooth transplantation according to the age (under 30 vs. over 30) was also investigated and it was examined whether there were any differences in each factor. Results: The average follow-up period was 12 months, followed by a maximum of 162 months. The 24-month cumulative survival rate of all auto-transplanted teeth was 91.7%, 83.1% at 60 months and the 162-month cumulative survival rate was 30.1%. There were no statistical differences between the causes of extraction of the recipient's teeth, differences in the condition of the opposing teeth, and differences under and over the age of 30. Conclusions: The survival rate of autogenous tooth transplantation appears to be influenced by the conditions of the donor tooth rather than the conditions of the recipient tooth. Although autogenous tooth transplantation cannot completely replace implant treatment, it is meaningful in that it can slightly delay or at least earn the time until implant placement is possible. | Park, Jin-Han; Kim, Yong-Gun; Suh, Jo-Young; Jin, Myoung-Uk; Lee, Jae-Mok | Kyungpook Natl Univ, Dept Periodontol, Sch Dent, Daegu 41940, South Korea; Kyungpook Natl Univ, Dept Conservat Dent, Sch Dent, Daegu 41940, South Korea | 57959011500; 55622694400; 7201514992; 56492091300; 17346330000 | musljin@knu.ac.kr;leejm@knu.ac.kr; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 11 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 1.28 | 2025-06-25 | 6 | 8 | autogenous tooth transplantation; long-term survival rate; pre-implant treatment | 370 AUTOTRANSPLANTED PREMOLARS; DENTAL IMPLANTS; TEETH; SUBSEQUENT; REPLANTATION; MAXILLARY; INCISORS | autogenous tooth transplantation; long-term survival rate; pre-implant treatment | Follow-Up Studies; Humans; Survival Rate; Tooth; Tooth Extraction; Tooth Fractures; Transplantation, Autologous; Treatment Outcome; autotransplantation; follow up; human; survival rate; tooth; tooth extraction; tooth fracture; transplantation; treatment outcome | English | 2022 | 2022-11 | 10.3390/medicina58111517 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Natural Course of Early Detected Acute Peripancreatic Fluid Collection in Moderately Severe or Severe Acute Pancreatitis | Background and Objectives: Acute peripancreatic fluid collection (APFC) is an acute local complication of acute pancreatitis (AP) according to the revised Atlanta classification. Sometimes APFC resolves completely, sometimes it changes into a pseudocyst or walled-off necrosis (WON), so called late complications. The aim of this study is to investigate the natural course of APFC detected on early computed tomography (CT) in moderately severe (MSAP) or severe AP (SAP). Materials and Methods: From October 2014 to September 2015, patients with MSAP or SAP were enrolled if there was APFC within 48 h of onset on imaging studies at six medical centers. The status of fluid collection was followed 4-8 weeks after onset. Initial laboratory findings, CT findings and clinical scoring systems were analyzed. Results: A total of 68 patients were enrolled and APFC was completely resolved in 32 (66.7%) patients in the MSAP group and 9 (34.6%) in the SAP group. Patients with a high bedside index for severity in acute pancreatitis (BISAP) score (>= 3 points) were common in the SAP group. C-reactive protein (CRP) after 48 h from admission and BUN level were also high in the SAP group. In multivariate analysis, BISAP score (>= 3 points), elevation of CRP after 48 h (>= 150 mg/L) and nasojejunal feeding after 48 h were risk factors for the development of late complications. Conclusions: Spontaneous resolution of APFC was more common in MSAP group and APFC can be changed to pseudocyst or WON in patients with elevated BISAP score, CRP level after 48 h, and non-improved abdominal pain. | Lee, Dong Wook; Kim, Ho Gak; Cho, Chang Min; Jung, Min Kyu; Heo, Jun; Cho, Kwang Bum; Kim, Sung Bum; Kim, Kook Hyun; Kim, Tae Nyeun; Han, Jimin; Kim, Hyunsoo | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu 41944, South Korea; Daegu Catholic Univ, Dept Internal Med, Sch Med, Daegu 42472, South Korea; Keimyung Univ, Dept Internal Med, Sch Med, Daegu 42601, South Korea; Yeungnam Univ, Dept Internal Med, Coll Med, Daegu 42415, South Korea; Daegu Fatima Hosp, Dept Internal Med, Daegu 41199, South Korea | Kim, Sung/I-2997-2017; KANG, MIN KYU/ACI-8824-2022; Kim, Seok-Hwan/G-9981-2015; Han, Jimin/AAC-5497-2022; Kim, Min/ACN-6827-2022 | 57202974895; 7410139763; 57158287600; 56783168100; 36448170600; 7403956834; 36619660100; 37094434600; 8449938100; 8694531200; 59053057100 | hgkim@cu.ac.kr; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 8 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0.96 | 2025-06-25 | 3 | 6 | acute pancreatitis; acute peripancreatic fluid collection; revised Atlanta classification | BLOOD UREA NITROGEN; ATLANTA CLASSIFICATION; GUIDELINES; MORTALITY; PREDICTION; MANAGEMENT | acute pancreatitis; acute peripancreatic fluid collection; revised Atlanta classification | Acute Disease; C-Reactive Protein; Hospitalization; Humans; Necrosis; Pancreatitis; Severity of Illness Index; C reactive protein; acute disease; complication; hospitalization; human; metabolism; necrosis; pancreatitis; severity of illness index | English | 2022 | 2022-08 | 10.3390/medicina58081131 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Novel Animal Model of Spontaneous Cerebral Petechial Hemorrhage Using Focused Ultrasound in Rats | Background and Objectives: Petechial cerebral hemorrhages can be caused by various factors, such as traumas, cerebral infarctions, and aging, and is related to the disruption of the blood-brain barrier or the cellular damage of blood vessels. However, there is no animal model that recapitulates cerebral petechial hemorrhages. Materials and Methods: Here, we implemented a petechial hemorrhage using a novel technology, i.e., microbubble-assisted focused ultrasound (MB + FUS). Results: This method increases the permeability of the blood-brain barrier by directly applying mechanical force to the vascular endothelial cells through cavitation of the microbubbles. Microbubble-enhanced cavitation has the advantage of controlling the degree and location of petechial hemorrhages. Conclusions: We thus generated a preclinical rat model using noninvasive focal MB + FUS. This method is histologically similar to actual petechial hemorrhages of the brain and allows the achievement of a physiologically resembling petechial hemorrhage. In the future, this method shall be considered as a useful animal model for studying the pathophysiology and treatment of petechial cerebral hemorrhages. | Yoon, Sang-Youl; Han, Mun; Lee, Chaejin; Lee, Eun-Hee; Kim, Moonsik; Kim, Kyoung-Tae; Hwang, Jeong-Hyun; Na, Sungdae; Park, Juyoung; Park, Ki-Su | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurosurg, Daegu 41404, South Korea; Daegu Gyeongbuk Med Innovat Fdn, Med Device Dev Ctr, Daegu 41061, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Neurosurg, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pathol, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ Hosp, Dept Biomed Engn, Daegu 41944, South Korea; Gachon Univ, Dept High Tech Med Device, Seongnam 13120, South Korea | 57195615457; 55671172700; 57211989339; 57212665883; 57195918515; 57201369790; 7403896906; 56366244500; 55329181100; 55932363100 | customplus@naver.com;munhan@dgmif.re.kr;cjleee01@gmail.com;ehlee@dgmif.re.kr;teiroa83@gmail.com;nskimkt7@knu.ac.kr;jhwang1027@gmail.com;bluepoison14@gmail.com;opedoors@gmail.com;kiss798@gmail.com; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 7 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0.16 | 2025-06-25 | 1 | 1 | focused ultrasound; blood-brain barrier; acoustic cavitation; ultrasound field stimulation | TRANSCRIPTION; EXPRESSION | acoustic cavitation; blood–brain barrier; focused ultrasound; ultrasound field stimulation | Animals; Blood-Brain Barrier; Cerebral Hemorrhage; Disease Models, Animal; Endothelial Cells; Microbubbles; Rats; animal; blood brain barrier; brain hemorrhage; diagnostic imaging; disease model; endothelium cell; microbubble; physiology; rat | English | 2022 | 2022-07 | 10.3390/medicina58070881 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Pancreas Involvement of Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type, Presenting as Acute Pancreatitis: A Case Report | Background: The main etiology of acute pancreatitis includes biliary origin and alcohol, although various other causes include drugs (i.e., L-asparaginase) or malignant tumors. Since accurate identification of etiologies is crucial for determining therapeutic planning, the assessment of cause should be performed as early as possible. Case presentation: A 57-year-old Korean man was admitted for chemotherapy. The patient did not drink alcohol for religious reason. 26 days prior to admission, a 4 cm-sized testicular mass was observed in ultrasound and he received right radial orchiectomy. Extranodal natural killer/T-cell lymphoma, nasal type, was diagnosed. After confirming no additional abnormal findings, chemotherapy (using the regimens Dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide) was begun. On Day 8 of chemotherapy, L-asparaginase was started and he complained of sudden onset epigastric pain after 2 days. Acute pancreatitis was diagnosed and, in order to determine if the acute pancreatitis occurred due to L-asparaginase or pancreas involvement of extranodal natural killer/T-cell lymphoma, endoscopic ultrasonography guided fine needle biopsy was performed and observed diffusely infiltrated tumor cells. Therefore, he was given a final diagnosis of acute pancreatitis due to pancreas involvement of extranodal natural killer/T-cell lymphoma, nasal type. Discussion: Acute pancreatitis caused by pancreas involvement of extranodal natural killer/T-cell lymphoma, nasal type, is a very rare disease but can occur during chemotherapy. To identify the cause of acute pancreatitis, endoscopic ultrasonography guided fine needle biopsy can be considered. | Lee, Dong Wook; Kim, Yun Jeong; Cho, Chang Min | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Emergency Med, Daegu 41944, South Korea | 57202974895; 57202340666; 57158287600 | storm5333@naver.com;eumto@naver.com;cmcho@knu.ac.kr; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 8 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0.16 | 2025-06-25 | 2 | 1 | extranodal natural killer; T-cell lymphoma; nasal type; acute pancreatitis; fine needle biopsy | acute pancreatitis; extranodal natural killer/T-cell lymphoma; fine needle biopsy; nasal type | Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Humans; Killer Cells, Natural; Lymphoma, Extranodal NK-T-Cell; Male; Middle Aged; Pancreas; Pancreatitis; antineoplastic agent; asparaginase; acute disease; case report; complication; human; male; middle aged; natural killer cell; NK T cell lymphoma; pancreas; pancreatitis; pathology | English | 2022 | 2022-08 | 10.3390/medicina58080991 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Predicting Severity of Acute Pancreatitis | Acute pancreatitis has a diverse etiology and natural history, and some patients have severe complications with a high risk of mortality. The prediction of the severity of acute pancreatitis should be achieved by a careful ongoing clinical assessment coupled with the use of a multiple-factor scoring system and imaging studies. Over the past 40 years, various scoring systems have been suggested to predict the severity of acute pancreatitis. However, there is no definite and ideal scoring system with a high sensitivity and specificity. The interest in new biological markers and predictive models for identifying severe acute pancreatitis testifies to the continued clinical importance of early severity prediction. Although contrast-enhanced computed tomography (CT) is considered the gold standard for diagnosing pancreatic necrosis, early scanning for the prediction of severity is limited because the full extent of pancreatic necrosis may not develop within the first 48 h of presentation. This article provides an overview of the available scoring systems and biochemical markers for predicting severe acute pancreatitis, with a focus on their characteristics and limitations. | Lee, Dong Wook; Cho, Chang Min | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu 41944, South Korea | 57202974895; 57158287600 | storm5333@naver.com;cmcho@knu.ac.kr; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 6 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 2.83 | 2025-06-25 | 35 | 36 | acute pancreatitis; severity; predicting factors | BLOOD UREA NITROGEN; APACHE-II SCORE; RISK-FACTOR; PLEURAL EFFUSION; MORTALITY; CT; ULTRASOUND; GUIDELINES; MANAGEMENT; NECROSIS | acute pancreatitis; predicting factors; severity | Acute Disease; Biomarkers; Humans; Pancreatitis, Acute Necrotizing; Predictive Value of Tests; Prognosis; Retrospective Studies; Severity of Illness Index; biological marker; acute disease; acute hemorrhagic pancreatitis; human; predictive value; prognosis; retrospective study; severity of illness index | English | 2022 | 2022-06 | 10.3390/medicina58060787 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Semantic Segmentation Dataset for AI-Based Quantification of Clean Mucosa in Capsule Endoscopy | Background and Objectives: Capsule endoscopy (CE) for bowel cleanliness evaluation primarily depends on subjective methods. To objectively evaluate bowel cleanliness, we focused on artificial intelligence (AI)-based assessments. We aimed to generate a large segmentation dataset from CE images and verify its quality using a convolutional neural network (CNN)-based algorithm. Materials and Methods: Images were extracted and divided into 10 stages according to the clean regions in a CE video. Each image was classified into three classes (clean, dark, and floats/bubbles) or two classes (clean and non-clean). Using this semantic segmentation dataset, a CNN training was performed with 169 videos, and a clean region (visualization scale (VS)) formula was developed. Then, measuring mean intersection over union (mIoU), Dice index, and clean mucosal predictions were performed. The VS performance was tested using 10 videos. Results: A total of 10,033 frames of the semantic segmentation dataset were constructed from 179 patients. The 3-class and 2-class semantic segmentation's testing performance was 0.7716 mIoU (range: 0.7031-0.8071), 0.8627 Dice index (range: 0.7846-0.8891), and 0.8927 mIoU (range: 0.8562-0.9330), 0.9457 Dice index (range: 0.9225-0.9654), respectively. In addition, the 3-class and 2-class clean mucosal prediction accuracy was 94.4% and 95.7%, respectively. The VS prediction performance for both 3-class and 2-class segmentation was almost identical to the ground truth. Conclusions: We established a semantic segmentation dataset spanning 10 stages uniformly from 179 patients. The prediction accuracy for clean mucosa was significantly high (above 94%). Our VS equation can approximately measure the region of clean mucosa. These results confirmed our dataset to be ideal for an accurate and quantitative assessment of AI-based bowel cleanliness. | Ju, Jeong-Woo; Jung, Heechul; Lee, Yeoun Joo; Mun, Sang-Wook; Lee, Jong-Hyuck | Pusan Natl Univ, Biomed Res Inst, Yangsan Hosp, Yangsan 50612, South Korea; Captos Co Ltd, Yangsan 50652, South Korea; Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu 41566, South Korea; Pusan Natl Univ, Sch Med, Dept Pediat, Yangsan Hosp, Yangsan 50612, South Korea; Seoreu Co Ltd, Busan 46288, South Korea | ; Jung, Heechul/HTL-7199-2023; Lee, Yeoun Joo/AHA-7302-2022 | 55651859700; 55652175200; 34877162300; 57023227700; 57491056900 | veryju@gmail.com;heechul@knu.ac.kr;moonmissing@gmail.com;soulwalker@naver.com;jhlee@seoreu.com; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 3 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 1.59 | 2025-06-25 | 8 | 10 | semantic segmentation; deep learning; capsule endoscopy; small bowel cleanliness; visualization scale | BOWEL PREPARATION; GRADING SYSTEM; QUALITY; VALIDATION; YIELD; SCORE | Capsule endoscopy; Deep learning; Semantic segmentation; Small bowel cleanliness; Visualization scale | Artificial Intelligence; Capsule Endoscopy; Humans; Mucous Membrane; Neural Networks, Computer; Semantics; artificial intelligence; capsule endoscopy; human; mucosa; procedures; semantics | English | 2022 | 2022-03 | 10.3390/medicina58030397 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Superior Mesenteric Artery Occlusion Caused by Infective Endocarditis and Worsened by Mycotic Aneurysm and Intracranial Hemorrhage: A Case Report | The superior mesenteric artery (SMA) is more commonly occluded than other abdominal arteries due to anatomical factors. Though rare, SMA occlusion is life-threatening. We present the case of a 50-year-old male patient who presented with fever and abdominal pain and was subsequently diagnosed with SMA embolism, SMA mycotic aneurysm, and infective endocarditis. Many patients visit the emergency room complaining of abdominal pain. Although SMA occlusion diagnosis is rare in these cases, detailed examination and close monitoring of patients are warranted considering the high mortality rate of this disease. | Kim, Changho; Oh, Tak-Hyuk | Kyungpook Natl Univ, Sch Med, Dept Emergency Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Thorac & Cardiovasc Surg, Daegu 41944, South Korea | 56441824200; 59278524700 | 9754130@hanmail.net; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 11 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0.32 | 2025-06-25 | 2 | 2 | superior mesenteric artery; endocarditis; mycotic aneurysm; intracranial hemorrhage | DIAGNOSIS | endocarditis; intracranial hemorrhage; mycotic aneurysm; superior mesenteric artery | Abdominal Pain; Aneurysm, Infected; Endocarditis; Endocarditis, Bacterial; Humans; Intracranial Hemorrhages; Male; Mesenteric Artery, Superior; Middle Aged; abdominal pain; bacterial endocarditis; brain hemorrhage; case report; complication; endocarditis; human; infected aneurysm; male; middle aged; superior mesenteric artery | English | 2022 | 2022-11 | 10.3390/medicina58111585 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The Changes in Trends of Lower Gastrointestinal Endoscopy Conducted in Children and Adolescents after the COVID-19 Outbreak in Korea | Background and Objectives: The coronavirus disease 2019 (COVID-19) pandemic has affected medical practice in diverse ways. We aimed to investigate the change in trends of lower gastrointestinal (LGI) endoscopy conducted in children and adolescents after the COVID-19 outbreak in Korea. Material and Methods: This was a multicenter, retrospective study conducted in Korea. We included children and adolescents aged Results: We included 1307 patients in this study. Colonoscopies, instead of sigmoidoscopies, were conducted in most patients in the postCOVID-19 era compared to those in the preCOVID-19 era (86.9% vs. 78.5%, p = 0.007). The diagnosis of inflammatory bowel disease (IBD) was also significantly higher in the postCOVID-19 era compared to the preCOVID-19 era (47.2% vs. 28.5%, p < 0.001). According to multivariate logistic regression analysis, age at LGI endoscopy, LGI bleeding indication, and IBD diagnosis were independently associated with the use of a colonoscopy over a sigmoidoscopy (odds ratio (OR) 1.19, 95% confidence interval (CI) 1.12-1.27, p < 0.001; OR 0.56, 95% CI 0.37-0.83, p = 0.005; OR 1.80, 95% CI 1.20-2.77, p = 0.006, respectively). Conclusions: The COVID-19 pandemic has changed LGI endoscopy practice trends of pediatric gastroenterologists in Korea, who tended to perform lesser LGI endoscopies compared to previous years while conducting significantly more colonoscopies than sigmoidoscopies in the postCOVID-19 era. Furthermore, these colonoscopies were significantly associated with the diagnosis of IBD, as well as a significant increase in IBD diagnosis in the postCOVID-19 era. | Lee, Sang Woo; Kang, Ben; Choi, Sujin; Choe, Byung-Ho; Kim, Yu Bin; Lee, Kyung Jae; Kim, Hyun Jin; Jang, Hyo-Jeong; Choi, So Yoon; Yi, Dae Yong; Choi, You Jin; Kim, Ju Young; Lee, Eun Hye; Lee, Yoo Min | Kyungpook Natl Univ, Sch Med, Dept Pediat, 130 Dongdeok Ro, Daegu 41944, South Korea; Ajou Univ, Dept Pediat, Sch Med, 164 World Cup Ro, Suwon 16499, South Korea; Hallym Univ, Dept Pediat, Coll Med, 1 Hallymdaehak Gil, Chunchon 24252, South Korea; Chungnam Natl Univ Hosp, Dept Pediat, 282 Munhwa Ro, Daejeon 35015, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Pediat, Sch Med, 1035 Dalgubeol Daero, Daegu 42601, South Korea; Kosin Univ, Coll Med, Dept Pediat, Gospel Hosp, 262 Gamcheon Ro, Busan 49267, South Korea; Chung Ang Univ, Chung Ang Univ Hosp, Dept Pediat, Coll Med, 102 Heukseok Ro, Seoul 06973, South Korea; Inje Univ, Dept Pediat, Ilsan Paik Hosp, Juhwa Ro 170, Goyang 10380, South Korea; Eulji Univ Hosp, Dept Pediat, 95 Dunsanseo Ro, Daejeon 35233, South Korea; Eulji Univ, Nowon Eulji Med Ctr, Dept Pediat, Sch Med, 68 Hangeulbiseok Ro, Seoul 01830, South Korea; Soonchunhyang Univ, Coll Med, Dept Pediat, Bucheon Hosp, Bucheon 14584, South Korea | Choe, Byung-Ho/KSM-6251-2024; Kim, Ju/AAV-3029-2020; Yi, Dae/G-1729-2014; lee, dong/I-9385-2017; Lee, Yun-Soo/AAA-7364-2022; Kim, Youngmin/C-7926-2019; lee, sangwoo/KUD-1906-2024; 康, 奔/JMQ-0812-2023 | 57369796700; 57194823199; 57223972405; 57574977300; 57212382905; 57022460500; 58975661600; 55355948500; 57207282105; 57190851975; 56063619400; 57202996384; 57188855950; 55588928200 | benkang@knu.ac.kr;flana512@naver.com; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 10 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0.32 | 2025-06-25 | 2 | 2 | colitis ulcerative; colonoscopy; COVID-19; Crohn's disease; inflammatory bowel diseases | PEDIATRIC COLONOSCOPY | colitis ulcerative; colonoscopy; COVID-19; Crohn’s disease; inflammatory bowel diseases | Adolescent; Child; COVID-19; Endoscopy, Gastrointestinal; Humans; Inflammatory Bowel Diseases; Pandemics; Republic of Korea; Retrospective Studies; adolescent; child; clinical trial; complication; epidemiology; gastrointestinal endoscopy; human; inflammatory bowel disease; multicenter study; pandemic; retrospective study; South Korea | English | 2022 | 2022-10 | 10.3390/medicina58101378 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Analysis of national surveillance of respiratory pathogens for community-acquired pneumonia in children and adolescents | Background Respiratory infections among children, particularly community-acquired pneumonia (CAP), is a major disease with a high frequency among outpatient and inpatient visits. The causes of CAP vary depending on individual susceptibility, the epidemiological characteristics of the community, and the season. We performed this study to establish a nationwide surveillance network system and identify the causative agents for CAP and antibiotic resistance in Korean children with CAP. Methods The monitoring network was composed of 28 secondary and tertiary medical institutions. Upper and lower respiratory samples were assayed using a culture or polymerase chain reaction (PCR) from August 2018 to May 2020. Results A total of 1023 cases were registered in patients with CAP, and PCR of atypical pneumonia pathogens revealed 422 cases of M. pneumoniae (41.3%). Respiratory viruses showed a positivity rate of 65.7% by multiplex PCR test, and human rhinovirus was the most common virus, with 312 cases (30.5%). Two hundred sixty four cases (25.8%) were isolated by culture, including 131 cases of S. aureus (12.8%), 92 cases of S. pneumoniae (9%), and 20 cases of H. influenzae (2%). The cultured, isolated bacteria may be colonized pathogen. The proportion of co-detection was 49.2%. The rate of antibiotic resistance showed similar results as previous reports. Conclusions This study will identify the pathogens that cause respiratory infections and analyze the current status of antibiotic resistance to provide scientific evidence for management policies of domestic respiratory infections. Additionally, in preparation for new epidemics, including COVID-19, monitoring respiratory infections in children and adolescents has become more important, and research on this topic should be continuously conducted in the future. | Roh, Eui Jeong; Lee, Mi-Hee; Lee, Ji Young; Kim, Hyo-Bin; Ahn, Young Min; Kim, Ja Kyoung; Kim, Hyoung Young; Jung, Sung-Su; Kim, Minji; Kang, Eun Kyeong; Yang, Eun-Ae; Lee, Soo Jin; Park, Yang; Seo, Ju-Hee; Lee, Eun; Yang, Eun Seok; Park, Kang Seo; Shin, Meeyong; Chung, Hai Lee; Jang, Yoon Young; Choi, Bong Seok; Jung, Jin-A; Yu, Seung Taek; Sung, Myongsoon; Kim, Jin Tack; Kim, Bong-Seong; Hwang, Yoon Ha; Sol, In-Suk; Yang, Hyeon-Jong; Han, Man Yong; Yew, Hae Young; Cho, Hyoung Min; Kim, Hye-Young; Ahn, Yeon-Hwa; Lee, Eun Sil; Kim, Dong Hyeok; Hwang, Kyujam; Jung, Sang Oun; Shim, Jung Yeon; Chung, Eun Hee | Chungnam Natl Univ Hosp, Dept Pediat, Daejeon, South Korea; Incheon Med Ctr, Dept Pediat, Incheon, South Korea; Hallym Univ, Dept Pediat, Chuncheon Sacred Heart Hosp, Chunchon, South Korea; Inje Univ, Dept Pediat, Sanggye Paik Hosp, Seoul, South Korea; Eulji Univ Hosp, Dept Pediat, Seoul, South Korea; Kangwon Natl Univ, Dept Pediat, Sch Med, Chunchon, South Korea; Pusan Natl Univ, Dept Pediat, Childrens Hosp, Yangsan, South Korea; Chungnam Natl Univ, Coll Med, Dept Pediat, Sejong Hosp, Sejong, South Korea; Dongguk Univ, Dept Pediat, Ilsan Hosp, Goyang, South Korea; Catholic Univ Korea, Dept Pediat, Daejeons St Marys Hosp, Daejeon, South Korea; Eulji Univ Hosp, Dept Pediat, Daejeon, South Korea; Wonkwang Univ, Dept Pediat, Sanbon Hosp, Gunpo, South Korea; Dankook Univ, Dept Pediat, Coll Med, Cheonan, South Korea; Chonnam Natl Univ, Chonnam Natl Univ Hosp, Dept Pediat, Med Sch, Gwangju, South Korea; Chosun Univ, Chosun Univ Hosp, Coll Med, Dept Pediat, Gwangju, South Korea; Presbyterian Med Ctr, Dept Pediat, Jeonju, South Korea; Soonchunhyang Univ, Dept Pediat, Bucheon Hosp, Bucheon, South Korea; Daegu Catholic Univ, Dept Pediat, Med Ctr, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Dong A Univ, Dept Pediat, Coll Med, Busan, South Korea; Wonkwang Univ, Dept Pediat, Sch Med, Iksan, South Korea; Soonchunhyang Univ Hosp, Dept Pediat, Gumi, South Korea; Catholic Univ Korea, Coll Med, Dept Pediat, Uijeongbu St Marys Hosp, Uijongbu, South Korea; Univ Ulsan, Gangneung Asan Hosp, Dept Pediat, Coll Med, Kangnung, South Korea; Busan St Marys Hosp, Dept Pediat, Busan, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Pediat, Sch Med, Seoul, South Korea; Soonchunhyang Univ Hosp, Dept Pediat, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Pediat, Sch Med, Seongnam, South Korea; Kogel Hosp, Dept Pediat, Daejeon, South Korea; Kwangju Christian Hosp, Dept Pediat, Kwangju, South Korea; Pusan Natl Univ Hosp, Dept Pediat, Pusan, South Korea; Bundang Jesaeng Hosp, Dept Pediat, Seongnam, South Korea; Korea Dis Control & Prevent Agcy KDCA, Bur Infect Dis Diag Control, Div Bacterial Dis, Sejong, South Korea; Chungnam Natl Univ, Dept Pediat, Sch Med, Daejeon, South Korea | Lee, Hoan/J-5616-2012; kim, jeeyoung/AFK-5620-2022; Park, Eunju/AAC-5266-2021; Lee, Min Young/GMX-1345-2022; Kim, Ju-Hyoung/N-1450-2019; Chung, Eunhee/AAX-6863-2020; Lee, Ha/ABF-6005-2020 | 57218885323; 56903238400; 57144743100; 57191720302; 56735321800; 7601384283; 59051653300; 57202732881; 56984405900; 55485131500; 55607660500; 57203597389; 57192714127; 22981399000; 58678989600; 36764244300; 56664911600; 8063810800; 7404006674; 57194429050; 56547873100; 7402897005; 56178493500; 57191221568; 35201365200; 35210645200; 57212011693; 56690279400; 15053595400; 16301607700; 57559889700; 57779499700; 57261054400; 57560766400; 57560987500; 57560987600; 8716633300; 55262166300; 7201856163; 35975693800 | jy7.shim@samsung.com;ehchung@cnu.ac.kr; | BMC INFECTIOUS DISEASES | BMC INFECT DIS | 1471-2334 | 22 | 1 | SCIE | INFECTIOUS DISEASES | 2022 | 3.7 | 52.6 | 2.53 | 2025-06-25 | 22 | 23 | Pneumonia; Child; Surveillance; Epidemiology | MYCOPLASMA-PNEUMONIAE; ETIOLOGY; EPIDEMIOLOGY; HOSPITALIZATION; INFECTIONS; PREVALENCE; ADULTS; AGE | Child; Epidemiology; Pneumonia; Surveillance | Adolescent; Child; Community-Acquired Infections; COVID-19; Humans; Multiplex Polymerase Chain Reaction; Pneumonia, Mycoplasma; Staphylococcus aureus; aminoglycoside; cephalosporin; lincomycin; macrolide; penicillin derivative; quinolone; tetracycline; vancomycin; antibiotic resistance; antibiotic sensitivity; Article; bacterial colonization; bacterium culture; bacterium detection; bacterium isolate; child; community acquired pneumonia; controlled study; coronavirus disease 2019; demography; disease registry; disease surveillance; drug use; epidemic; evidence based practice; female; groups by age; Haemophilus influenzae; health care policy; human; infant; lower respiratory tract; major clinical study; male; multiplex polymerase chain reaction; Mycoplasma pneumoniae; nonhuman; patient care; patient monitoring; patient participation; polymerase chain reaction; respiratory tract infection; Rhinovirus; school child; Staphylococcus aureus; Streptococcus pneumoniae; tertiary care center; upper respiratory tract; adolescent; community acquired infection; microbiology; Mycoplasma pneumoniae; procedures | English | 2022 | 2022-04-04 | 10.1186/s12879-022-07263-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Post-acute COVID-19 syndrome in patients after 12 months from COVID-19 infection in Korea | Background As the coronavirus disease 2019 (COVID-19) pandemic continues to progress, awareness about its long-term impacts has been growing. To date, studies on the long-term course of symptoms, factors associated with persistent symptoms, and quality of life after 12 months since recovery from acute COVID-19 have been limited. Methods A prospective online survey (First: September 8, 2020-September 10, 2020; Second: May 26, 2021-June 1, 2021) was conducted on recovered patients who were previously diagnosed with COVID-19 between February 13, 2020 and March 13, 2020 at Kyungpook National University Hospital. Responders aged between 17 and 70 years were included in the study. Overall, 900 and 241 responders were followed up at 6 and 12 months after recovery from COVID-19 in the first and second surveys, respectively. Clinical characteristics, self-reported persistent symptoms, and EuroQol-5-dimension (EQ5D) index score were investigated for evaluating quality of life. Results The median period from the date of the first symptom onset or COVID-19 diagnosis to the time of the survey was 454 (interquartile range [IQR] 451-458) days. The median age of the responders was 37 (IQR 26.0-51.0) years, and 164 (68.0%) responders were women. Altogether, 11 (4.6%) responders were asymptomatic, and 194 (80.5%), 30 (12.4%), and 6 (2.5%) responders had mild, moderate, and severe illness, respectively. Overall, 127 (52.7%) responders still experienced COVID-19-related persistent symptoms and 12 (5.0%) were receiving outpatient treatment for such symptoms. The main symptoms were difficulty in concentration, cognitive dysfunction, amnesia, depression, fatigue, and anxiety. Considering the EQ5D index scores, only 59.3% of the responders did not have anxiety or depression. Older age, female sex, and disease severity were identified as risk factors for persistent neuropsychiatric symptoms. Conclusion COVID-19-related persistent symptoms improved over time; however, neurological symptoms can last longer than other symptoms. Continuous careful observation of symptom improvement and multidisciplinary integrated research on recovered COVID-19 patients are required. | Kim, Yoonjung; Bitna-Ha; Kim, Shin-Woo; Chang, Hyun-Ha; Kwon, Ki Tae; Bae, Sohyun; Hwang, Soyoon | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Div Infect Dis,Dept Internal Med, 130 Dongdeok Ro, Daegu 41944, South Korea | ; Hwang, Soyoon/HHM-5762-2022; Kim, Sooyeon/AAA-8521-2022; Kim, Jihyun/F-6940-2013 | 57203160508; 57432828300; 8710731500; 7407521688; 9733850500; 57219699506; 57203160675 | ksw2kms@knu.ac.kr; | BMC INFECTIOUS DISEASES | BMC INFECT DIS | 1471-2334 | 22 | 1 | SCIE | INFECTIOUS DISEASES | 2022 | 3.7 | 52.6 | 11.03 | 2025-06-25 | 90 | 96 | COVID-19; SARS-CoV-2; Sequelae; Persistent symptoms; Long COVID; Quality of life | SEQUELAE | COVID-19; Long COVID; Persistent symptoms; Quality of life; SARS-CoV-2; Sequelae | Adolescent; Adult; Aged; COVID-19; COVID-19 Testing; Female; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Republic of Korea; Young Adult; adolescent; adult; aged; amnesia; anxiety disorder; Article; cognitive defect; controlled study; coronavirus disease 2019; depression; disease severity; European Quality of Life 5 Dimensions questionnaire; fatigue; female; follow up; human; major clinical study; male; middle aged; nasopharyngeal swab; nonhuman; prevalence; prospective study; quality of life; quarantine; real time reverse transcription polymerase chain reaction; risk factor; scoring system; self report; Severe acute respiratory syndrome coronavirus 2; South Korea; young adult; complication; epidemiology | English | 2022 | 2022-01-27 | 10.1186/s12879-022-07062-6 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Relationship between the appropriateness of antibiotic treatment and clinical outcomes/medical costs of patients with community-acquired acute pyelonephritis: a multicenter prospective cohort study | Background: Inappropriate use of antibiotics not only increases antibiotic resistance as collateral damage but also increases clinical failure rates and medical costs. The purpose of this study was to determine the relationship between the appropriateness of antibiotic prescription and outcomes of community-acquired acute pyelonephritis (CA-APN). Methods: A multicenter prospective cohort study was conducted at eight hospitals in Korea between September 2017 and August 2018. All hospitalized patients aged >= 19 years who were diagnosed with CA-APN on admission were recruited. The appropriateness of empirical and definitive antibiotics, as well as the appropriateness of antibiotic treatment duration and route of administration, was evaluated in accordance with the guideline and expert opinions. Clinical outcomes and medical costs were compared between patients who were administered antibiotics 'appropriately' and 'inappropriately.' Results: A total of 397 and 318 patients were eligible for the analysis of the appropriateness of empirical and definitive antibiotics, respectively. Of them, 10 (2.5%) and 18 (5.7%) were administered 'inappropriately' empirical and definitive antibiotics, respectively. Of the 119 patients whose use of both empirical and definitive antibiotics was classified as 'optimal,' 57 (47.9%) received antibiotics over a longer duration than that recommended; 67 (56.3%) did not change to oral antibiotics on day 7 of hospitalization, even after stabilization of the clinical symptoms. Patients who were administered empirical antibiotics 'appropriately' had shorter hospitalization days (8 vs. 10 days, P = 0.001) and lower medical costs (2381.9 vs. 3235.9 USD, P = 0.002) than those who were administered them 'inappropriately.' Similar findings were observed for patients administered both empirical and definitive antibiotics 'appropriately' and those administered either empirical or definitive antibiotics 'inappropriately'. Conclusions: Appropriate use of antibiotics leads to better outcomes, including reduced hospitalization duration and medical costs. | Yoon, Choseok; Park, Se Yoon; Kim, Bongyoung; Kwon, Ki Tae; Ryu, Seong-yeol; Wie, Seong-Heon; Jo, Hyun-uk; Kim, Jieun; Hong, Kyung-Wook; Kim, Hye In; Kim, Hyun Ah; Kim, Mi-Hee; Bae, Mi-Hyun; Sohn, Yong-Hak; Kim, Jieun; Lee, Yangsoon; Pai, Hyunjoo | Republ Korea Army, Infantry Div 27, Med Team, Med Commend Internal Med, Hwacheon, South Korea; Soonchunhyang Univ, Seoul Hosp, Coll Med, Div Infect Dis,Dept Internal Med, Seoul, South Korea; Hanyang Univ, Coll Med, Dept Internal Med, 222-1 Wangsimni Ro, Seoul 04763, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Internal Med, Daegu, South Korea; Catholic Univ Korea, St Vincent Hosp, Coll Med, Div Infect Dis,Dept Internal Med, Seoul, South Korea; Good Moonhwa Hosp, Dept Urol, Busan, South Korea; Gyeongsang Natl Univ, Gyeongsang Natl Univ Hosp, Sch Med, Div Infect Dis,Dept Internal Med, Jinju, South Korea; Daegu Fatima Hosp, Dept Internal Med, Daegu, South Korea; Hanyang Univ, Coll Med, Dept Lab Med, Seoul, South Korea; Seegene Med Fdn, Seoul, South Korea; Soonchunhyang Univ, Seoul Hosp, Coll Med, Dept Lab Med, Seoul, South Korea | Hong, Kyung-Wook/T-3067-2018; Kim, Seog/J-5403-2012; Pai, Hyunjoo/M-7492-2018; Kim, Jong/K-3445-2013; Kim, Hanjin/KYP-2633-2024; Lee, Min Young/GMX-1345-2022; Lee, Yangsoon/C-9751-2015; Kim, Woo/AAG-1822-2019 | 57439094500; 55259986400; 55622077200; 9733850500; 9733513600; 12796392700; 57219027371; 51963871600; 38461203300; 57208153832; 57059615500; 56001471000; 57032150100; 35270009900; 56528660800; 56107271700; 57225132406 | sobakas@hanyang.ac.kr; | BMC INFECTIOUS DISEASES | BMC INFECT DIS | 1471-2334 | 22 | 1 | SCIE | INFECTIOUS DISEASES | 2022 | 3.7 | 52.6 | 0.57 | 2025-06-25 | 5 | 5 | Acute pyelonephritis; Urinary tract infection; Antibiotics; Korea | URINARY-TRACT-INFECTIONS; ESCHERICHIA-COLI; EARLY SWITCH; GUIDELINES; IMPACT; EPIDEMIOLOGY; THERAPY; WOMEN | Acute pyelonephritis; Antibiotics; Korea; Urinary tract infection | Anti-Bacterial Agents; Drug Resistance, Microbial; Hospitalization; Humans; Prospective Studies; Pyelonephritis; antibiotic agent; antiinfective agent; acute pyelonephritis; adult; antibiotic therapy; Article; clinical outcome; cohort analysis; community acquired infection; controlled study; female; health care cost; hospital admission; hospital patient; hospitalization; human; Korea; major clinical study; male; middle aged; multicenter study; observational study; prescription; prospective study; treatment duration; young adult; antibiotic resistance; clinical trial; pyelonephritis | English | 2022 | 2022-02-01 | 10.1186/s12879-022-07097-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The effect of the multimodal intervention including an automatic notification of catheter days on reducing central line-related bloodstream infection: a retrospective, observational, quasi-experimental study | Background A central venous catheter (CVC) is an important medical device, but it could be preceding infection and the risk of central line-associated bloodstream infection (CLABSI). CLABSI is a common healthcare-associated infection but results in high cost and mortality; therefore, various efforts to reduce CLABSI have been attempted. Methods This is a retrospective, observational, quasi-experimental study in the intensive care unit (ICU) of a single tertiary care hospital. We reviewed and analysed the data of CLABSI rates and days from the insertion to the removal of the temporary CVC between January 2018 and June 2021 with transient periods over 9 months. Sequentially, all patients with the CVC in the ICU underwent the following interventions: maximal barrier precaution, automatic notification of catheter days and 2% chlorhexidine gluconate bathing. A segmented regression analysis of interrupted time series was conducted to compare the CLABSI rates before and after the introduction of multimodal interventions. During study periods, the impact of interventions on CLABSI was evaluated using multivariate logistic regression analyses. Results A total of 76,504 patient-days, 28,312 catheter days and 66 CLABSI cases were reviewed in ICU-hospitalised patients. As additional interventions, the CLABSI rate declined from 3.1 per 1000 CVC days to 1.2 per 1000 CVC days in post-interventions. In the pre-intervention and post-intervention periods, 4146 patents had one more short-term CVC. In the multivariate logistic regression analyses, multimodal intervention was one of determinants reducing CLABSI rates (odds ratio (OR), 0.52 [95% confidence interval {CI}, 0.28-0.94]). Indwelling time of CVC over 10 days was the risk factor for CLABSI rates (OR, 6.27 [95% CI, 3.36-12.48]). Of the three interventions, the automatic notification of catheter days was associated with decreased median monthly total CVC days and duration of CVC days per patient. Conclusions Multidisciplinary and evidence-based interventions could lead to a decrease in the CLABSI rates. Moreover, the automatic notification of catheter days of the electronic medical healthcare system has shortened the time of indwelling CVC. | Bae, Sohyun; Kim, Yoonjung; Chang, Hyun-Ha; Kim, Sungjin; Kim, Hyun-Ji; Jeon, Hyeyoung; Cho, Juhee; Lee, Juyoung; Chae, Hwajin; Han, Gyeongmin; Kim, Shin-Woo | Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Div Infect Dis, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Infect Control Off, Daegu, South Korea | ; Kim, Tae-You/J-2750-2012; Cho, Juhee/ABD-2280-2021 | 57219699506; 57203160508; 7407521688; 57789657000; 57789657100; 57576266900; 57789657200; 57789014300; 57576052800; 57790073400; 57189703358 | ksw2kms@knu.ac.kr; | BMC INFECTIOUS DISEASES | BMC INFECT DIS | 1471-2334 | 22 | 1 | SCIE | INFECTIOUS DISEASES | 2022 | 3.7 | 52.6 | 1.03 | 2025-06-25 | 15 | 10 | Infection control; Central venous catheter; Bloodstream infection; Automated medical records system | CENTRAL-VENOUS-CATHETER; INTENSIVE-CARE-UNIT; RISK-FACTORS; PREVENTION; ASSOCIATION; OUTCOMES; BUNDLE; RATES | Automated medical records system; Bloodstream infection; Central venous catheter; Infection control | Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Central Venous Catheters; Humans; Observational Studies as Topic; Retrospective Studies; Sepsis; chlorhexidine gluconate; adult; aged; Article; automation; catheter infection; catheter removal; clinical effectiveness; controlled study; disease notification; female; hospital patient; human; intensive care unit; major clinical study; male; observational study; retrospective study; risk factor; safety; tertiary care center; adverse device effect; adverse event; bacteremia; catheter infection; central venous catheter; central venous catheterization; procedures; sepsis | English | 2022 | 2022-07-08 | 10.1186/s12879-022-07588-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Development of an Animal Stereotactic Device for Preclinical Research on Tumor Response After Stereotactic Radiosurgery | BACKGROUND: In gamma knife radiosurgery, the tumor response to radiation is an important predictor of clinical treatment results. Since brain tumors have different char-acteristics and growth patterns, depending on the type, the tumors' response to radiation are also different. Compared with various other clinical treatments, there is a dearth of research on the development of gamma knife-magnetic resonance imaging (MRI) preclinical experimental equip-ment. Hence, the identification of preclinical equipment necessity for experimental animals will provide meaning-ful data for the provision of clinical assistance to humans.OBJECTIVES: A device for stereotactic radiosurgery capable of MRI in small animals was developed. The feasibility of creating a preplan by means of small animal images was then assessed.METHODS: A device for stereotaxic surgery of small animals using a 48-channel MRI coil was developed using a 3 dimensional printer. Rat brain-MRI images were ob-tained with a 3.0 T MRI scanner using a multi-channel coil. The acquired MRI images were transferred to a Gamma -Plan workstation to establish a preplan.RESULTS: To gamma rays to the targeted site on animals, a positioning device combined with a G-frame was mounted on a gamma knife. Planning of radiosurgery based on MRI images became possible with GammaPlan workstations.CONCLUSIONS: Preclinical experiments using small animals are possible with the use of stereotactic devices. In clinical treatment, preclinical experimental results will provide meaningful information. | Kim, Byungmok; Yang, Ji-Ung; Chang, Yongmin; Choi, Hea Jung; Jang, Kyungeun; Yoon, Sang-Youl; Park, Seong-Hyun | Kyungpook Natl Univ, Dept Med & Biol Engn, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Neurosurg, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Radiol, Daegu, South Korea; Korea Inst Radiol & Med Sci KIRAMS, Div Appl RI, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Mol Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurosurg, Daegu, South Korea; Asan Med Ctr, Dept Radiat Oncol, Seoul, South Korea; AIRS Med, Seoul, South Korea | 57220575172; 57212217968; 7501840633; 57220585921; 56740018300; 57195615457; 21734563200 | nsdoctor@naver.com; | WORLD NEUROSURGERY | WORLD NEUROSURG | 1878-8750 | 1878-8769 | 166 | SCIE | CLINICAL NEUROLOGY;SURGERY | 2022 | 2 | 52.8 | 0 | 2025-06-25 | 0 | 0 | Animal SRS frame adapters; Animal stereotactic device; Gamma knife neurosurgery; Multi-channel coil; Stereotactic radiosurgery | GAMMA-KNIFE RADIOSURGERY; MRI | Animal SRS frame adapters; Animal stereotactic device; Gamma knife neurosurgery; Multi-channel coil; Stereotactic radiosurgery | Animals; Brain Neoplasms; Humans; Magnetic Resonance Imaging; Radiosurgery; Rats; animal; brain tumor; diagnostic imaging; human; nuclear magnetic resonance imaging; procedures; radiosurgery; rat | English | 2022 | 2022-10 | 10.1016/j.wneu.2022.08.007 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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