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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Reconstruction of the initial function from the solution of the fractional wave equation measured in two geometric settings | Photoacoustic tomography (PAT) is a novel and rapidly developing technique in the medical imaging field that is based on generating acoustic waves inside of an object of interest by stimulating non-ionizing laser pulses. This acoustic wave was measured by using a detector on the outside of the object it was then converted into an image of the human body after several inversions. Thus, one of the mathematical problems in PAT is reconstructing the initial function from the solution of the wave equation on the outside of the object. In this study, we consider the fractional wave equation and assume that the point-like detectors are located on the sphere and hyperplane. We demonstrate a way to recover the initial function from the data, namely, the solution of the fractional wave equation, measured on the sphere and hyperplane. | Jung, Hyungyeong; Moon, Sunghwan | Kyungpook Natl Univ, Sch Math, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Dept Math, Daegu, South Korea | 57451362400; 56063426100 | sunghwan.moon@knu.ac.kr; | ELECTRONIC RESEARCH ARCHIVE | ELECTRON RES ARCH | 2688-1594 | 30 | 12 | SCIE | MATHEMATICS | 2022 | 0.8 | 51.4 | 0.25 | 2025-06-25 | 1 | 1 | photoacoustic; tomography; wave equation; fractional derivative | MELLIN INTEGRAL TRANSFORM; INVERSION FORMULAS | Fractional derivative; Photoacoustic; Tomography; Wave equation | English | 2022 | 2022 | 10.3934/era.2022225 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Riemannian Concircular Structure Manifolds | In this manuscript, we give the definition of Riemannian concircular structure manifolds. Some basic properties and integrability condition of such manifolds are established. It is proved that a Riemannian concircular structure manifold is semisymmetric if and only if it is concircularly flat. We also prove that the Riemannian metric of a semisymmetric Riemannian concircular structure manifold is a generalized soliton. In this sequel, we show that a conformally flat Riemannian concircular structure manifold is a quasi-Einstein manifold and its scalar curvature satisfies the partial differential equation Delta r = partial derivative(2)r/partial derivative t(2) + alpha(n - 1)partial derivative r/partial derivative t. To validate the existence of Riemannian concircular structure manifolds, we present some non-trivial examples. In this series, we show that a quasi-Einstein manifold with a divergence free concircular curvature tensor is a Riemannian concircular structure manifold. | Chaubey, Sudhakar Kumar; Suh, Young Jin | Univ Technol & Appl Sci Shinas, Dept Informat Technol, Sect Math, POB 77, Shinas 324, Oman; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Kyungpook Natl Univ, RIRCM, Daegu 41566, South Korea | ; Chaubey, S./ABB-6952-2021 | 36117508600; 7202260479 | sudhakar.chaubey@shct.edu.om;yjsuh@knu.ac.kr; | FILOMAT | FILOMAT | 0354-5180 | 36 | 19 | SCIE | MATHEMATICS, APPLIED;MATHEMATICS | 2022 | 0.8 | 51.4 | 0.99 | 2025-06-25 | 3 | 4 | Riemannian manifolds; (RCS)(n)-manifolds; curvature tensors; symmetric spaces; torse-forming vector field; concircular vector field; generalized soliton | VECTOR-FIELDS; SPACES | (RCS)<sub>n</sub>-manifolds; concircular vector field; curvature tensors; generalized soliton; Riemannian manifolds; symmetric spaces; torse-forming vector field | English | 2022 | 2022 | 10.2298/fil2219699c | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Validation of items on the NDDIE and PHQ-9 associated with suicidal ideation during suicidality screening in patients with epilepsy | Purpose: : This study was performed to validate individual items on the Neurological Disorders Depression Inventory for Epilepsy (NDDIE) and the Patient Health Questionnaire-9 (PHQ-9), as well as their total scores, during suicidality screening of patients with epilepsy (PWE). Methods: : PWE were assessed with the Mini International Neuropsychiatric Interview (MINI), the NDDIE, and the PHQ-9. Moderate to high suicidality, as assessed by the Suicidality Module of the MINI, was considered the standard measurement. Each item and overall scores for the NDDIE and PHQ-9 were evaluated by receiver operating characteristic (ROC) curve analyses. The optimal cutoff criteria were identified as those with the highest Youden index. Results: : Of the 213 participants, 20 (9.4%) had moderate to high suicidality. Item 4 on the NIDDE and item 9 on the PHQ-9, representing suicidal ideation, showed the best psychometric properties for suicidality. A cutoff of >1 for item 4 on the NDDIE showed an area under the ROC curve (AUC) of 0.853, a sensitivity of 90.0%, and a specificity of 72.0%. A cutoff >0 for item 9 on the PHQ-9 showed an AUC of 0.851, a sensitivity of 90.0%, and a specificity of 74.6%. The specificities and positive predictive values of item 4 on the NDDIE and item 9 on the PHQ-9 were higher in patients with depression than those in the overall patient population. Conclusion: : Item 4 of NDDIE and Item 9 of PHQ-9 showed value in screening for suicidality. Use of these items may rapidly identify suicidality among PWE. | Kim, Hyo Jae; Jeon, Ji-Ye; Kim, Hyun-Woo; Lee, Sang-Ahm | Univ Ulsan, Asan Med Ctr, Dept Neurol, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Neurol, Chilgok, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Neurol, Yangsan, South Korea | Lee, Dong/J-2778-2012 | 57193096910; 57194943660; 57226027023; 57190211641 | salee@amc.seoul.kr; | SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | SEIZURE-EUR J EPILEP | 1059-1311 | 1532-2688 | 99 | SCIE | CLINICAL NEUROLOGY;NEUROSCIENCES | 2022 | 3 | 51.7 | 1.14 | 2025-06-25 | 10 | 10 | Epilepsy; Suicidality; PHQ-9; NDDIE; Suicidal ideation | DISORDERS DEPRESSION INVENTORY; RISK-FACTORS; PEOPLE; PREVALENCE; VALIDITY; VERSION | Epilepsy; NDDIE; PHQ-9; Suicidal ideation; Suicidality | anticonvulsive agent; antidepressant agent; adult; Article; controlled study; depression; depression assessment; epilepsy; epileptic patient; female; high risk patient; human; instrument validation; intermediate risk patient; Korean (people); major clinical study; male; mini international neuropsychiatric interview; Neurological Disorders Depression Inventory for Epilepsy; Patient Health Questionnaire 9; predictive value; prevalence; psychometry; receiver operating characteristic; screening; sensitivity and specificity; suicidal behavior; suicidal ideation; Youden index | English | 2022 | 2022-07 | 10.1016/j.seizure.2022.05.011 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Editorial Material | Assessment of Medication Adherence and Pharmacist Intervention Are Important for the Care of Patients with Inflammatory Bowel Disease | Kim, Eun Sil; Kang, Ben | Sungkyunkwan Univ, Sch Med, Kangbuk Samsung Hosp, Dept Pediat, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea | 康, 奔/JMQ-0812-2023 | 57205500267; 57194823199 | benkang@knu.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 5 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0.72 | 2025-06-25 | 1 | 1 | NONADHERENCE | Chronic Disease; Humans; Inflammatory Bowel Diseases; Medication Adherence; Pharmacists; Crohn disease; decision making; Editorial; health care system; health insurance; human; inflammatory bowel disease; medication compliance; patient care; pharmacist; ulcerative colitis; chronic disease; inflammatory bowel disease; medication compliance | English | 2022 | 2022-09 | 10.5009/gnl220358 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Association between Fecal Calprotectin and Mucosal Healing in Pediatric Patients with Crohn's Disease Who Have Achieved Sustained Clinical Remission with Anti-Tumor Necrosis Factor Agents | Background/Aims: Although mucosal healing (MH) is acknowledged as the treatment target in the treat-to-target era, there are limitations on repeated endoscopic examinations, especially in pediatric patients. We aimed to investigate whether fecal calprotectin (FC) could serve as a surrogate marker for the assessment of MH in pediatric patients with Crohn's disease (CD) who have achieved sustained clinical remission (CR) while treated with anti-tumor necrosis factor (TNF) agents. Methods: This multicenter retrospective cross-sectional study included pediatric CD patients who had sustained a CR for at least 6 months with anti-TNF agents and who simultaneously underwent ileocolonoscopy and FC tests during follow-up. MH was defined as the absence of any ulcer on ileocolonoscopy. Results: A total of 131 patients were included in this study. MH was observed in 87 patients (66.7%). The FC level was significantly lower in patients with MH than in those without MH (median 49.0 mg/kg vs 599.0 mg/kg; p<0.001). According to the multivariate logistic regression analysis, FC was the only factor associated with MH (odds ratio, 0.62; 95% confidence interval [CI], 0.52 to 0.73; p<0.001). According to the receiver operating characteristic curve analysis, the optimal cutoff value for FC for the association with MH was <140 mg/kg (area under the curve 0.890, 95% CI 0.829 to 0.951, sensitivity 78.2%, specificity 88.6%, p<0.001). Conclusions: FC was associated with MH in pediatric patients with CD who had achieved a sustained CR for at least 6 months with anti-TNF agents. In these patients, FC can be used to stratify patients and guide decisions regarding ileocolonoscopy in the treat-to-target era. | Lee, Yoo Min; Choi, Sujin; Choe, Byung-Ho; Jang, Hyo-Jeong; Kim, Seung; Koh, Hong; Kim, Eun Sil; Kim, Mi Jin; Choe, Yon Ho; Kang, Ben | Soonchunhyang Univ, Dept Pediat, Coll Med, Bucheon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Crohns & Colitis Assoc Daegu Gyeongbuk CCAiD, Daegu, South Korea; Keimyung Univ, Dept Pediat, Sch Med, Daegu, South Korea; Yonsei Univ, Severance Hosp, Dept Pediat, Coll Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Pediat, Sch Med, Seoul, South Korea | ; 康, 奔/JMQ-0812-2023; Choe, Byung-Ho/KSM-6251-2024; Kim, Mi Jin/GXH-9639-2022; Lee, Yong Jae/GLR-4153-2022 | 55588928200; 57223972405; 57574977300; 55355948500; 57196230792; 35789948700; 57205500267; 56638815200; 21333712100; 57194823199 | yonho.choe@samsung.com;benkang@knu.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 1 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0.44 | 2025-06-25 | 5 | 5 | Crohn disease; Infliximab; Adalimumab; Child; Adolescent | INFLAMMATORY-BOWEL-DISEASE; ENDOSCOPIC ACTIVITY; ACTIVITY INDEX; CHILDREN; MARKER; LACTOFERRIN; DIAGNOSIS; THERAPY; RELAPSE; SCORE | Adalimumab; Adolescent; Child; Crohn disease; Infliximab | Biomarkers; Child; Crohn Disease; Cross-Sectional Studies; Feces; Humans; Infliximab; Leukocyte L1 Antigen Complex; Retrospective Studies; Severity of Illness Index; Tumor Necrosis Factor Inhibitors; adalimumab; calgranulin; infliximab; tumor necrosis factor inhibitor; biological marker; calgranulin; tumor necrosis factor inhibitor; adolescent; age distribution; Article; child; controlled study; Crohn disease; cross-sectional study; disease classification; disease marker; feces level; female; follow up; human; ileocolonoscopy; intestine mucosa; major clinical study; male; medical decision making; multicenter study; pediatric patient; remission; retrospective study; school child; sensitivity and specificity; sex difference; tertiary care center; chemistry; clinical trial; feces; pathology; severity of illness index | English | 2022 | 2022-01 | 10.5009/gnl20300 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Comparison between Pediatric Crohn's Disease and Ulcerative Colitis at Diagnosis in Korea: Results from a Multicenter, Registry-Based, Inception Cohort Study | Background/Aims: We aimed to compare the differences in pediatric Crohn's disease (CD) and ulcerative colitis (UC) at diagnosis in Korea. Methods: This was a multicenter, registry-based, inception cohort study conducted at five centers in Korea between 2013 and 2017. Baseline demographics, clinical characteristics, and results from laboratory, endoscopic, radiologic examinations were compared between pediatric CD and UC patients who were <19 years old at diagnosis. Results: A total 307 patients were included (227 CD [73.9%] and 80 UC [26.1%]). The male to female ratio was 2.49:1 for CD, and 1.49:1 for UC (p=0.019). Median age at diagnosis was 14.4 years (interquartile range, 12.4 to 16.2) for CD, and 14.4 years (interquartile range, 11.7 to 16.5) for UC (p=0.962). Hematochezia was the only dominant symptom in UC patients compared to CD patients (86.2% vs 30.8%, p<0.001). White blood cell counts, platelet counts, erythrocyte sedimentation rate, and C-reactive protein levels were significantly higher, and serum albumin level was significantly lower in CD patients than in UC patient. Anti- Saccharomyces cerevisiae antibody was positive in 44.5% and 16.2% of CD and UC patients, respectively (p<0.001), and antineutrophil cytoplasmic antibody was positive in 15.0% and 58.8% of CD and UC patients, respectively (p<0.001). Terminal ileal involvement was prominent in CD, while rectal involvement was more prominent in UC. Small bowel involvement and perianal perforating diseases were also more prominent in CD. Conclusions: This is the first a multicenter study in Korea to compare the differences between pediatric CD and UC at diagnosis in Korea. A large-scale, national study is expected to better clarify these findings in the future. (Gut Liver 2022;16:921-929) | Park, Sowon; Kang, Ben; Kim, Seung; Choi, Sujin; Suh, Hyo Rim; Kim, Eun Sil; Park, Ji Hyung; Kim, Mi Jin; Choe, Yon Ho; Lee, Yeoun Joo; Park, Jae Hong; Ryoo, Eell; Koh, Hong; Choe, Byung-Ho | Yonsei Univ, Severance Hosp, Coll Med, Dept Pediat, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Pediat, Seoul, South Korea; Pusan Natl Univ, Sch Med, Dept Pediat, Yangsan, South Korea; Gachon Univ, Coll Med, Dept Pediat, Incheon, South Korea | Choe, Byung-Ho/KSM-6251-2024; 康, 奔/JMQ-0812-2023; Kim, Mi Jin/GXH-9639-2022; Lee, Yeoun Joo/AGP-1813-2022 | 57020161000; 57194823199; 57196230792; 57223972405; 57203059359; 57205500267; 57326465000; 56638815200; 21333712100; 34877162300; 57202928590; 19837506900; 35789948700; 57574977300 | bhchoi@knu.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 6 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0.52 | 2025-06-25 | 5 | 6 | Inflammatory bowel disease; Korea; Crohn disease; Ulcerative colitis; Child | INFLAMMATORY-BOWEL-DISEASE; C-REACTIVE PROTEIN; CLINICAL CHARACTERISTICS; 5-YEAR ANALYSES; CHILDREN; TRENDS | Child; Crohn disease; Inflammatory bowel disease; Korea; Ulcerative colitis | Adult; Child; Cohort Studies; Colitis, Ulcerative; Female; Humans; Male; Registries; Republic of Korea; Young Adult; albumin; C reactive protein; calgranulin; hemoglobin; neutrophil cytoplasmic antibody; abdominal pain; adolescent; anus fistula; Article; biopsy; body mass; body weight loss; capsule endoscopy; child; cohort analysis; colonoscopy; computer assisted tomography; Crohn disease; Crohn Disease Activity Index; diagnostic procedure; diarrhea; disease registry; endoscopy; erythrocyte sedimentation rate; esophagogastroduodenoscopy; female; fever; hematochezia; hematocrit; histology; human; inflammatory bowel disease; intestine endoscopy; Korea; laboratory test; leukocyte count; magnetic resonance enterography; major clinical study; male; mouth ulcer; multicenter study; perianal abscess; radiology; ulcerative colitis; vomiting; adult; clinical trial; epidemiology; register; South Korea; ulcerative colitis; young adult | English | 2022 | 2022-11 | 10.5009/gnl210488 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effect of Sodium Alginate on Gastrointestinal Symptoms after Esophagogastroduodenoscopy with Biopsy: Randomized Controlled Trial | Background/Aims: After esophagogastroduodenoscopy (EGD) with biopsy, some patients experience gastrointestinal symptoms. This study investigated the effect of sodium alginate on biopsy-related gastrointestinal symptoms. Methods: In this open-label, randomized, controlled trial, patients undergoing EGD with biopsy were randomly assigned to a treatment or control group. In the treatment group, sodium alginate was orally administered for 3 days after EGD. Patients completed questionnaires about their gastrointestinal symptoms at baseline (past week), the day after returning home, and after another 3 days. Gastrointestinal symptoms, including abdominal pain, epigastric pain/soreness, heartburn, acid reflux, nausea/vomiting, borborygmus, abdominal distension, and belching, were rated using an upper gastrointestinal symptom rating scale (GSRS). Results: A total of 210 persons (138 men) who underwent EGD with biopsy were enrolled and allocated to the treatment (n=104) or control (n=106) group. At baseline, the demographic factors and GSRS scores were not different between the control and treatment groups. The epigastric pain/soreness score increased in the control group after endoscopic biopsy (+0.056), whereas the score was decreased in the treatment group (-0.067) (p=0.042). In the treatment group, the scores for acid regurgitation and epigastric soreness decreased during follow-up from those at baseline (p<0.05), whereas there were no significant reductions in the control group. The scores for belching and borborygmus decreased during follow-up only in the treatment group. Abdominal bloating decreased in both the control and treatment groups. Conclusions: Sodium alginate reduced epigastric pain/soreness after EGD with biopsy. Therefore, the prescription of sodium alginate should be considered after endoscopic biopsy. | Nam, Su Youn; Lee, Sang Won; Jeon, Seong Woo; Kwon, Yong Hwan | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Daegu, South Korea | ; Jeon, Seongwoo/AAU-4618-2020 | 55617028500; 57209989084; 9733636500; 55775556800 | swjeon@knu.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 1 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0.17 | 2025-06-25 | 2 | 2 | Alginates; Biopsy; Abdominal pain | GASTRIC-MUCOSA; REGENERATION; EFFICACY; INJURY; ULCER | Abdominal pain; Alginates; Biopsy | Alginates; Biopsy; Endoscopy, Digestive System; Gastroesophageal Reflux; Heartburn; Humans; Male; alginic acid; lamina g; alginic acid; abdominal distension; abdominal pain; adult; aged; Article; bloating; borborygmus; controlled study; demography; digestive system disease assessment; drug effect; endoscopic biopsy; epigastric pain; erosive gastritis; eructation; esophagogastroduodenoscopy; female; follow up; gastroesophageal reflux; gastrointestinal symptom; heartburn; Helicobacter infection; histopathology; human; human tissue; major clinical study; male; nausea; questionnaire; randomized controlled trial; reflux esophagitis; treatment duration; upper gastrointestinal symptom rating scale; very elderly; vomiting; biopsy; digestive tract endoscopy; gastroesophageal reflux; heartburn | English | 2022 | 2022-01 | 10.5009/gnl20298 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effectiveness and Safety of Golimumab in Patients with Ulcerative Colitis: A Multicenter, Prospective, Postmarketing Surveillance Study | Background/Aims: Golimumab has been used for patients with ulcerative colitis (UC) since 2013. However, there is limited data on the effectiveness and safety of the real-world use of golimumab in Asian patients. Methods: This was a multicenter, prospective, observational study. We enrolled patients with moderate-to-severe UC who were administered subcutaneous golimumab at 46 medical centers between May 2014 and November 2019. The primary outcome was the effectiveness and safety of golimumab at week 22. Clinical outcomes and adverse events were assessed according to partial Mayo score at weeks 0, 2, 6, 14, and 22. Results: A total of 130 patients were included (mean age: 45.7 +/- 16.0 years). The clinical response/remission rates at weeks 2, 6, 14, and 22 were 40.4%/22.9%, 56.0%/35.8%, 70.6%/49.5%, and 67.9%148.6%, respectively. Based on full Mayo score at week 14, clinical response and remission rates were 84.2% and 39.5%, respectively. Mucosal healing rate was 65.8%. In multivariate analysis with logistic regression, longer disease duration was significantly associated with a higher clinical response rate (adjusted odds ratio [aOR], 1.136; 95% confidence interval [CI), 1.006 to 1.282; p=1.040 at week 6; aOR, 1.256; 95% CI, 1.049 to 1.503; p=0.013 at week 22). A higher baseline Mayo endoscopic subscore was significantly associated with a lower clinical response rate at week 6 (aOR, 0.248; 95% CI, 0.089 to 0.692; p=0.008). The incidence of adverse drug reactions was 4.6% (6/130, nine events). No serious unexpected adverse drug reactions or deaths were reported. Conclusions: Golimumab was effective and safe as an induction and maintenance treatment for Korean patients with moderate-to-severe UC. | Yu, Jongwook; Park, Soo Jung; Kim, Hyung Wook; Lim, Yun Jeong; Park, Jihye; Cha, Jae Myung; Ye, Byong Duk; Kim, Tae Oh; Kim, Hyun-Soo; Lee, Hyun Seok; Jung, Su Young; Kim, Youngdoe; Choi, Chang Hwan | Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Inst Gastroenterol, Coll Med, Seoul, South Korea; Pusan Natl Univ, Dept Internal Med, Yangsan Hosp, Yangsan, South Korea; Dongguk Univ, Coll Med, Dept Internal Med, Ilsan Hosp, Goyang, South Korea; Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea; Kyung Hee Univ, Dept Internal Med, Sch Med, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Dept Gastroenterol, Coll Med, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Inflammatory Bowel Dis Ctr, Coll Med, Seoul, South Korea; Inje Univ, Dept Internal Med, Haeundae Paik Hosp, Busan, South Korea; Yonsei Univ, Dept Internal Med, Wonju Coll Med, Wonju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Daegu, South Korea; Janssen Korea Ltd, Med Affairs, Seoul, South Korea; Chung Ang Univ, Dept Internal Med, Coll Med, Seoul, South Korea | Kim, Sara/F-2951-2013; Cheon, Jung-Eun/J-5684-2012; Park, Jihye/AAC-1333-2022; Kim, Seong Cheol/ABD-1493-2022; LIM, Yun Jeong/KVY-6446-2024; Kim, Yong-Sik/J-5418-2012; Kim, Hyung/J-5451-2012; Yu, Jongwook/HMV-5712-2023; Ye, Byong/AAF-4955-2020 | 57015768000; 56042287100; 56231863100; 56501161800; 56693432000; 57203991065; 14069472300; 57189056554; 55739553100; 36647886100; 57898510700; 57192809503; 56799609000 | gicch@cau.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 5 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0.44 | 2025-06-25 | 4 | 6 | Ulcerative colitis; Golimumab; Tumor necrosis factor-alpha | CLINICAL-RESPONSE; TUBERCULOSIS; MODERATE; REMISSION; PHARMACOKINETICS; INDUCTION; THERAPY; AGENTS; DRUGS | Golimumab; Tumor necrosis factor-α; Ulcerative colitis | Adult; Antibodies, Monoclonal; Colitis, Ulcerative; Drug-Related Side Effects and Adverse Reactions; Humans; Middle Aged; Prospective Studies; Remission Induction; Severity of Illness Index; Treatment Outcome; golimumab; tumor necrosis factor; golimumab; monoclonal antibody; abdominal pain; adult; allergic rhinitis; anemia; Article; clinical effectiveness; controlled clinical trial; controlled study; disease duration; drug response; drug safety; endoscopy; female; fever; gastrointestinal disease; heart palpitation; human; infection; infestation; major clinical study; male; middle aged; multicenter study; observational study; pneumonia; prospective study; rectum hemorrhage; respiratory tract disease; thorax disease; tuberculosis; ulcerative colitis; adverse drug reaction; clinical trial; remission; severity of illness index; treatment outcome | English | 2022 | 2022-09 | 10.5009/gnl210335 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Exploration of Potential Gut Microbiota-Derived Biomarkers to Predict the Success of Fecal Microbiota Transplantation in Ulcerative Colitis: A Prospective Cohort in Korea | Background/Aims: Although fecal microbiota transplantation (FMT) has been proven as one of the promising treatments for patients with ulcerative colitis (UC), potential prognostic markers regarding the clinical outcomes of FMT remain elusive. Methods: We collected fecal samples of 10 participants undergoing FMT to treat UC and those from the corresponding donors. We categorized them into two groups: responders and nonresponders. Sequencing of the bacterial 16S rRNA gene was conducted on the samples to explore bacterial composition. Results: Analyzing the gut microbiota of patients who showed different outcomes in FMT presented a distinct microbial niche. Source tracking analysis showed the nonresponder group had a higher rate of preservation of donor microbiota, underscoring that engraftment degrees are not one of the major drivers for the success of FMT. At the phylum level, Bacteroidetes bacteria were significantly depleted (p<0.003), and three genera, including Enterococcus, Rothia, and Pediococcus, were enriched in the responder group before FMT (p=0.003, p=0.025, and p=0.048, respectively). Furthermore, we applied a machine learning algorithm to build a prediction model that might allow the prediction of FMT outcomes, which yielded an area under the receiver operating characteristic (ROC) curve of 0.844. Notably, the microbiota-based model was much better at predicting outcomes than the clinical features model (area under the ROC curve=0.531). Conclusions: This study is the first to suggest the significance of indigenous microbiota of recipients as a critical factor. The result highlights that bacterial composition should be evaluated before FMT to select suitable patients and achieve better efficiency. (Gut Liver, Published online August 17, 2022) | Kang, Gi-Ung; Park, Sowon; Jung, Yeongyun; Jee, Jai J.; Kim, Min-Sueng; Lee, Seungjun; Lee, Dong-Woo; Shin, Jae-Ho; Koh, Hong | Kyungpook Natl Univ, Dept Appl Biosci, Daegu, South Korea; Yonsei Univ, Severance Hosp, Severance Fecal Microbiota Transplantat Ctr, Dept Pediat,Coll Med, Seoul, South Korea; Pukyong Natl Univ, Dept Food Sci & Nutr, Busan, South Korea; Yonsei Univ, Dept Biotechnol, Seoul, South Korea | ; Lee, Seungjun/S-9826-2019; Lee, Jin-Woong/IQT-2676-2023; shin, Jaeho/K-6792-2013 | 57211635810; 57020161000; 57197833801; 57416948300; 57224861638; 56437333700; 57195068659; 57224125922; 35789948700 | jhshin@knu.ac.kr;KHONG@yuhs.ac; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 5 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0.61 | 2025-06-25 | 9 | 7 | Fecal microbiota transplantation; Fecal microbiota transplantation outcome; Ma-chine learning; Ulcerative colitis | INFLAMMATORY-BOWEL-DISEASE; CROHNS-DISEASE; MECHANISMS; REMISSION; INTENSITY; INDUCTION | Fecal microbiota transplantation; Fecal microbiota transplantation outcome; Machine learning; Ulcerative colitis | Biomarkers; Colitis, Ulcerative; Fecal Microbiota Transplantation; Feces; Gastrointestinal Microbiome; Humans; Prospective Studies; RNA, Ribosomal, 16S; Treatment Outcome; azathioprine; biological marker; biological product; budesonide; mesalazine; RNA 16S; steroid; biological marker; RNA 16S; adult; Article; Bacteroidetes; clinical article; clinical feature; cohort analysis; controlled study; Enterococcus; fecal microbiota transplantation; feces; female; human; intestine flora; longitudinal study; machine learning; male; Pediococcus; prediction; prospective study; receiver operating characteristic; retrospective study; RNA sequencing; Rothia; species composition; treatment response; ulcerative colitis; fecal microbiota transplantation; treatment outcome; ulcerative colitis | English | 2022 | 2022-09 | 10.5009/gnl210369 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Prognosis and Clinical Characteristics of Patients with Pancreatic Ductal Adenocarcinoma Diagnosed by Endoscopic Ultrasonography but Indeterminate on Computed Tomography | Background/Aims: Endoscopic ultrasonography (EUS) provides high-resolution images and is superior to computed tomography (CT) scan in diagnosing small pancreatic ductal adenocarcinoma (PDAC). As a result, the use of EUS for early detection of PDAC has attracted attention. This study aimed to identify the clinical and radiological characteristics of patients with PDAC diagnosed by EUS but not found on CT scan. Methods: The medical records of patients diagnosed with PDAC at 12 tertiary referral centers in Korea from January 2003 to April 2019 were reviewed. This study included patients with pancreatic masses not clearly observed on CT scan but identified on EUS. The clinical characteristics and radiological features of the patients were analyzed, and survival analysis was performed. Results: A total of 83 patients were enrolled. The most common abnormal CT findings other than a definite mass was pancreatic duct dilatation, which was identified in 61 patients (73.5%). All but four patients underwent surgery. The final pathologic stages were as follows: IA (n=31, 39.2%), IB (n=8, 10.1%), IIA (n=20, 25.3%), IIB (n=17, 21.5%), III (n=2, 2.5%), and IV (n=1, 1.4%). The 5-year survival rate of these patients was 50.6% (95% confidence interval, 38.8% to 66.7%). Elevated liver function testing and R1 resection emerged as significant predictors of mortality in the multivariable Cox regression analysis. Conclusions: This multicenter study demonstrated favorable long-term prognosis in patients with PDAC diagnosed by EUS but indeterminate on CT scan. EUS should be considered for patients with suspected PDAC but indeterminate on CT scan. (Gut Liver 2022;16:474-482) | Ko, Sung Woo; Kim, Tae Hyeon; Song, Tae Jun; Kim, Seong-Hun; Seo, Dong-Wan; Yoon, Jai Hoon; Cho, Chang Min; Cho, Jae Hee; Choi, Jun-Ho; Lee, Dong Wook; Lee, Sang Hyub; Yoon, Seung Bae; Lee, Tae Hoon; Kim, Gwang Ha; Chun, Hoon Jai | Asan Med Ctr, Dept Gastroenterol, Seoul, South Korea; Wonkwang Univ, Dept Internal Med, Sch Med, Iksan, South Korea; Jeonbuk Natl Univ, Dept Internal Med, Res Inst Clin Med, Biomed Res Inst,Jeonbuk Natl Univ Hosp, Jeonju, South Korea; Hanyang Univ, Dept Internal Med, Div Gastroenterol, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Gachon Univ, Dept Internal Med, Coll Med, Incheon, South Korea; Dankook Univ, Dept Internal Med, Coll Med, Cheonan, South Korea; Daegu Catholic Univ, Dept Internal Med, Sch Med, Daegu, South Korea; Seoul Natl Univ, Coll Med, Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Coll Med, Seoul Natl Univ Hosp, Liver Res Inst, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea; Soonchunhyang Univ, Sch Med, Dept Internal Med, Div Gastroenterol,Cheonan Hosp, Cheonan, South Korea; Pusan Natl Univ, Sch Med, Dept Internal Med, Busan, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Korea Univ, Inst Digest Dis & Nutr, Dept Internal Med, Div Gastroenterol & Hepatol,Coll Med, Seoul, South Korea | ; Cho, Jae Hee/AAL-8192-2020; Lee, Tae/B-1160-2013; Lee, Taehoon/D-9498-2017; Kim, Gwang Ha/ABF-3932-2021; Song, Taejun/JVZ-2733-2024 | 57215925662; 36062469400; 26028951400; 57206878084; 7201422887; 7403587413; 57158287600; 58838319500; 55661671700; 57202974895; 36062488800; 35217323900; 16506642900; 35214772400; 7202215162 | kth@wku.ac.kr;medi01@naver.com; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 3 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0.35 | 2025-06-25 | 4 | 4 | Pancreatic neoplasms; Endosonography; Kaplan-Meier estimate | LYMPH-NODE RATIO; CANCER; CT; PANCREATICODUODENECTOMY; DILATATION; RESECTION; SERIES; IMPACT; SIGNS; RISK | Endosonography; Kaplan-Meier estimate; Pancreatic neoplasms | Carcinoma, Pancreatic Ductal; Endosonography; Humans; Pancreatic Ducts; Pancreatic Neoplasms; Prognosis; Retrospective Studies; Tomography, X-Ray Computed; alanine aminotransferase; alkaline phosphatase; aspartate aminotransferase; bilirubin; CA 19-9 antigen; contrast medium; gamma glutamyltransferase; midazolam; pethidine; propofol; abdominal pain; adult; Article; bile duct dilatation; body weight loss; cancer prognosis; cancer staging; color Doppler flowmetry; common bile duct; computer assisted tomography; controlled study; diagnostic test accuracy study; echography; endoscopic ultrasonography; female; fever; fine needle aspiration biopsy; follow up; human; jaundice; liver function test; lymph node metastasis; lymphadenopathy; magnetic resonance cholangiopancreatography; major clinical study; male; mortality; neoadjuvant chemotherapy; overall survival; pancreatic ductal carcinoma; pancreaticoduodenectomy; positron emission tomography; predictive value; retrospective study; tumor volume; clinical trial; diagnostic imaging; endoscopic ultrasonography; multicenter study; pancreas carcinoma; pancreas tumor; pancreatic duct; pathology; prognosis; x-ray computed tomography | English | 2022 | 2022-05 | 10.5009/gnl210123 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Correction | Prognosis and Clinical Characteristics of Patients with Pancreatic Ductal Adenocarcinoma Diagnosed by Endoscopic Ultrasonography but Indeterminate on Computed Tomography (vol 16, pg 474, 2022) | Ko, Sung Woo; Kim, Tae Hyeon; Song, Tae Jun; Kim, Seong-Hun; Seo, Dong-Wan; Yoon, Jai Hoon; Cho, Chang Min; Cho, Jae Hee; Choi, Jun-Ho; Lee, Dong Wook; Lee, Sang Hyub; Yoon, Seung Bae; Lee, Tae Hoon; Kim, Gwang Ha; Chun, Hoon Jai | Asan Med Ctr, Dept Gastroenterol, Seoul, South Korea; Wonkwang Univ, Dept Internal Med, Sch Med, Iksan, South Korea; Jeonbuk Natl Univ, Dept Internal Med, Res Inst Clin Med, Biomed Res Inst,Jeonbuk Natl Univ Hosp, Jeonju, South Korea; Hanyang Univ, Div Gastroenterol, Dept Internal Med, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Gachon Univ, Dept Internal Med, Coll Med, Incheon, South Korea; Dankook Univ, Coll Med, Dept Internal Med, Cheonan, South Korea; Daegu Catholic Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Liver Res Inst, Coll Med, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea; Soonchunhyang Univ, Sch Med, Div Gastroenterol, Dept Internal Med,Cheonan Hosp, Cheonan, South Korea; Pusan Natl Univ, Dept Internal Med, Pusan Natl Univ Hosp, Sch Med, Pusan, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Korea Univ, Coll Med, Div Gastroenterol & Hepatol, Dept Internal Med,Inst Digest Dis & Nutr, Seoul, South Korea | Cho, Jae Hee/AAL-8192-2020; Kim, Gwang Ha/ABF-3932-2021; Lee, Tae/B-1160-2013; Song, Taejun/JVZ-2733-2024 | 57215925662; 36062469400; 26028951400; 57206878084; 7201422887; 7403587413; 57158287600; 58838319500; 55661671700; 57202974895; 36062488800; 35217323900; 16506642900; 35214772400; 7202215162 | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 16 | 5 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2022 | 3.4 | 52.2 | 0 | 2025-06-25 | 0 | 0 | erratum | English | 2022 | 2022-09 | 10.5009/gnl210123.e | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Alterations of Power Spectral Density in Salience Network during Thought-action Fusion Induction Paradigm in Obsessive-compulsive Disorder | Objective: Recent studies highlighted the triple-network model which illustrated the interactions among three large-scale networks including salience network (SN). The functional magnetic resonance imaging used in this study was designed to investigate the characteristics of three large-scale networks associated with the thought-action fusion (TAF) in patients with obsessive-compulsive disorder (OCD) using power spectral density (PSD) analysis. Methods: This study included 32 OCD patients and 38 age-matched healthy controls (HC). The TAF task was modified from the experiment of Rassin. PSD from time courses in large-scale networks of each subject was measured to compare between the groups for both TAF and resting state. Results: In SN, OCD reported lower power in the low-frequency domain of SN compared to HC using the two-sample t test during the TAF task (t = -2.395, p = 0.019) but not in the resting state. The PSD in the low-frequency domain of the SN had a significant negative correlation with state score in the guilty inventory (r = -0.361, p = 0.042) in OCD patients. Conclusion: This study suggests that OCD patients showed reduced SN power which can be prominent in a certain situation, such as TAF. In addition, the PSD alterations in SN cause difficulty in processing ambiguous emotional cues in social situations, and the difficulty can be connected with a negative feeling (e.g., guilt). | Lee, Sang Won; Kim, Eunji; Jang, Tae Yang; Choi, Heajung; Kim, Seungho; Song, Huijin; Hwang, Moon Jung; Chang, Yongmin; Lee, Seung Jae | Kyungpook Natl Univ, Dept Psychiat, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Psychiat, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Med & Biol Engn, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Psychiat, Daegu, South Korea; Seoul Natl Univ Hosp, Biomed Res Inst, Seoul, South Korea; GE Hlth Korea, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Mol Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Radiol, Daegu, South Korea | Lee, Seung/AAI-1191-2020 | 55820414800; 57215273419; 57219848497; 57220585921; 57218284791; 8231186700; 57200114449; 7501840633; 58509400200 | ychang@knu.ac.kr;jayleemd@knu.ac.kr; | CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE | CLIN PSYCHOPHARM NEU | 1738-1088 | 2093-4327 | 20 | 3 | SCIE | NEUROSCIENCES;PHARMACOLOGY & PHARMACY | 2022 | 3.2 | 52.3 | 0.4 | 2025-06-25 | 3 | 3 | Obsessive-compulsive disorder; Power spectral density; Salience network; Triple-network model | DEFAULT-MODE; ANTERIOR CINGULATE; BRAIN NETWORKS; FUNCTIONAL CONNECTIVITY; SUPPRESSION; METAANALYSIS; PSYCHOPATHOLOGY; RESPONSIBILITY; MODULATION; CORTEX | Obsessive-compulsive disorder; Power spectral density; Salience network; Triple-network model | adult; analysis; angular gyrus; anterior insula; Article; clinical article; clinical assessment tool; controlled study; correlation analysis; default mode network; electric shock; emotion; female; functional magnetic resonance imaging; guilt; guilty inventory; hippocampus; human; inferior frontal gyrus; inferior parietal cortex; inferior temporal gyrus; male; medial prefrontal cortex; middle occipital gyrus; middle temporal gyrus; obsessive compulsive disorder; posterior cingulate; power spectral density; precentral sulcus; precuneus; putamen; reaction time; resting state network; salience network; social behavior; thinking; thought action fusion | English | 2022 | 2022-08 | 10.9758/cpn.2022.20.3.415 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Acute Twin-to-Twin Transfusion Syndrome Resulting in Fetal Bradycardia and Neonatal Death: A Case Report | In monochorionic twins with no evidence of chronic twin-to-twin transfusion syndrome or twin anemia-polycythemia sequence, a sudden onset of fetal transfusion syndrome after the second trimester of pregnancy is defined as acute twin-to-twin transfusion syndrome. Labor pain, change in the fetal position, and birth order are known risk factors for this condition, and the hemoglobin level of the donor twin is usually reported to be <12 g/dL. We report a recent case of acute twin-to-twin transfusion syndrome without effective labor pain causing cervical changes, resulting in fetal bradycardia and neonatal death after birth; however, the anemia of the donor twin was not as severe as has been reported previously in twin-to-twin transfusion syndrome cases. | Kim, Mi Ju; Kim, Hyun Mi; Cha, Hyun-Hwa; Kim, Haemin; Kim, Hyo-Shin; Seong, Won Joon | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Dept Obstet & Gynecol, Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Obstet & Gynecol, Sch Med, Daegu 41404, South Korea | Kim, Mi Ju/HGU-8470-2022; Kim, Young-Il/ISS-7678-2023 | 55908927600; 57219838830; 37033517800; 57222634904; 57868107000; 26656946000 | wjseong@knu.ac.kr; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 12 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0.16 | 2025-06-25 | 1 | 1 | acute twin-to-twin transfusion syndrome; anemia of donor twin; fetal bradycardia; monochorionic twin; neonatal death | WEIGHT DISCORDANCE; RISK | acute twin-to-twin transfusion syndrome; anemia of donor twin; fetal bradycardia; monochorionic twin; neonatal death | Anemia; Bradycardia; Female; Fetofetal Transfusion; Humans; Infant, Newborn; Labor Pain; Perinatal Death; Polycythemia; Pregnancy; Twins, Monozygotic; anemia; bradycardia; case report; complication; female; human; labor pain; monozygotic twins; newborn; newborn anemia; perinatal death; polycythemia; pregnancy | English | 2022 | 2022-12 | 10.3390/medicina58121813 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical Characteristics of TZAP (ZBTB48) in Hepatocellular Carcinomas from Tissue, Cell Line, and TCGA | Background and Objectives: ZBTB48 is a telomere-related protein that has been renamed telomeric zinc finger-associated protein (TZAP). It favorably binds to elongated telomeres to regulate their appropriate length. However, TZAP expression has not been investigated in hepatocellular carcinomas (HCC). Materials and Methods: The clinical significance of TZAP expression in 72 HCC was investigated. Additionally, its findings were supported by open big data and cancer cell lines. Results: TZAP expression level was not associated with the clinical parameters of HCC. TZAP expression induced a poorer survival result (overall survival, p = 0.020; disease-free survival, p = 0.012). TCGA data showed TZAP expression was more frequently found in HCCs with hepatitis C infection (p = 0.023). However, TCGA data revealed that TZAP expression did not predict HCC prognosis. In a cell line study, TZAP inhibition via siRNA suppressed PLC/PRF/5 cell growth; however, cell viability was increased in HepG2 cells. Conclusions: We presented the clinical and prognostic values of TZAP expression in HCC tissues and cancer cell lines. Additionally, the TCGA results also revealed a significant role for TZAP expression. TZAP expression may involve HCC progression and its prognosis. | Jung, Soo-Jung; Kil, So-Hyun; Lee, Hye Won; Park, Tae In; Lee, Yun-Han; Kim, Jongwan; Lee, Jae-Ho | Keimyung Univ, Sch Med, Dept Anat, 1095 Dalgubeol Daero, Daegu 42601, South Korea; CHA Univ, CHA Gumi Med Ctr, Dept Anesthesiol & Pain Med, Gumi 39295, South Korea; Keimyung Univ, Dept Pathol, Sch Med, Daegu 42601, South Korea; Kyungpook Natl Univ, Dept Pathol, Sch Med, Daegu 42601, South Korea; Keimyung Univ, Sch Med, Dept Mol Med, Daegu 42601, South Korea; Dong Eui Inst Technol, Dept Biomed Lab Sci, 54 Yangji Ro, Busan 47230, South Korea | Lee, Jae-Ho/I-1935-2019 | 57193347340; 58025470900; 57907713300; 7401801814; 57191172104; 57205021741; 55224798300 | dahyun@dit.ac.kr;anato82@dsmc.or.kr; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 12 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0.16 | 2025-06-25 | 0 | 1 | TZAP; telomere; hepatocellular carcinoma; ZBTB48 | TELOMERE LENGTH; CANCER | hepatocellular carcinoma; telomere; TZAP; ZBTB48 | Carcinoma, Hepatocellular; Cell Line, Tumor; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Prognosis; Telomere; Transcription Factors; Zinc Fingers; DNA binding protein; transcription factor; ZBTB48 protein, human; zinc finger protein; gene expression regulation; genetics; human; liver cell carcinoma; liver tumor; pathology; prognosis; telomere; tumor cell line | English | 2022 | 2022-12 | 10.3390/medicina58121778 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Correlation between Maternal Weight Gain in Each Trimester and Fetal Growth According to Pre-Pregnancy Maternal Body Mass Index in Twin Pregnancies | Background andObjectives: This study aimed to determine the correlation between maternal weight gain in each trimester and fetal growth according to pre-pregnancy maternal body mass index in twin pregnancies. Materials and Methods: We conducted a retrospective review of the medical records of 500 twin pregnancies delivered at 28 weeks' gestation or greater at a single tertiary center between January 2011 and December 2020. We measured the height, pre-pregnant body weight, and maternal body weight of women with twin pregnancies and evaluated the relationship between the maternal weight gain at each trimester and fetal growth restriction according to pre-pregnancy body mass index. Results: The overweight pregnant women were older than the normal or underweight pregnant women, and the risk of gestational diabetes was higher. The underweight pregnant women were younger, and the incidence of preterm labor and short cervical length during pregnancy was higher in the younger group. In normal weight pregnant women, newborn babies' weight was heavier when their mothers gained weight, especially when they gained weight in the second trimester. Mothers' weight gain in the first trimester was not a significant factor to predict fetal growth. The most predictive single factor for the prediction of small neonates was weight gain during 24-28 and 15-18 weeks, and the cutoff value was 6.2 kg (area under the curve 0.592, p < 0.001). Conclusions: In twin pregnancy, regardless of the pre-pregnant body mass index, maternal weight gain affected fetal growth. Furthermore, weight gain in the second trimester of pregnancy is considered a powerful indicator of fetal growth, especially in normal weight pregnancies. | Kim, Mi Ju; Kim, Hyun Mi; Cha, Hyun-Hwa; Seong, Won Joon | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Obstet & Gynecol, Daegu 41944, South Korea | Kim, Mi Ju/HGU-8470-2022 | 55908927600; 57219838830; 37033517800; 26656946000 | wjseong@knu.ac.kr; | MEDICINA-LITHUANIA | MEDICINA-LITHUANIA | 1010-660X | 1648-9144 | 58 | 9 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 2.6 | 52.4 | 0 | 2025-06-25 | 0 | 0 | twin pregnancy; maternal weight gain; fetal growth; maternal complications; neonatal outcomes | OF-MEDICINE GUIDELINES; PERINATAL OUTCOMES; ASSOCIATION; PATTERNS; RISK | fetal growth; maternal complications; maternal weight gain; neonatal outcomes; twin pregnancy | Body Mass Index; Female; Fetal Development; Gestational Weight Gain; Humans; Infant, Newborn; Pregnancy; Pregnancy, Twin; Retrospective Studies; Thinness; Weight Gain; body mass; body weight gain; female; fetus development; gestational weight gain; human; newborn; pregnancy; retrospective study; twin pregnancy; underweight | English | 2022 | 2022-09 | 10.3390/medicina58091209 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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