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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Large field-of-view microlens array with low crosstalk and uniform angular resolution for tabletop integral imaging display Tabletop autostereoscopic displays have the advantage of displaying realistic three-dimensional (3D) content. In particular, the Integral imaging (InIm) method is superior in tabletop displays, as it is possible to make the system small using microlens arrays (MLA). Off-the-shelf MLAs have a small field of view (FOV) and are unsuitable for tabletop displays where the half viewing angle is typically around 45 degrees. The MLA for tabletop display also needs to have uniform angular resolution and low crosstalk to display 3D content. In this paper, we designed a new MLA with a multilayer structure and a reversed lens shape. This lens array has a wide viewing angle of -58 degrees to +58 degrees, with uniform angular resolution and low crosstalk of less than 0.2. We implemented a tabletop display using our MLA and verified its properties experimentally. The misallocation error of the elemental image is experimentally measured and compensated for as well. Heo, Daerak; Kim, Beomjun; Lim, Sungjin; Moon, Woonchan; Lee, Dongkil; Hahn, Joonku Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehak Ro, Daegu 41566, South Korea; Korea Photon Technol Inst, Spatial Opt Informat R&D Ctr, Gwangju, South Korea 57197871664; 57216150371; 56706721300; 56340460500; 37047045400; 10142501600 jhahn@knu.ac.kr; JOURNAL OF INFORMATION DISPLAY J INFORM DISPLAY 1598-0316 2158-1606 24 1 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY 2023 3.7 40.0 1.13 2025-06-25 10 10 Three-dimensional display; integral imaging; microlens design; crosstalk reduction; equidistant lens 3-DIMENSIONAL DISPLAY; FLOATING DISPLAY; LIGHT-FIELD; SYSTEM crosstalk reduction; equidistant lens; integral imaging; microlens design; Three-dimensional display Field emission displays; Microlenses; Nematic liquid crystals; Optical instrument lenses; Stereo image processing; Three dimensional displays; 3D content; Angular resolution; Crosstalk reduction; Equidistant lens; Integral imaging; Micro lens; Micro-lens arrays; Microlens design; Tabletop displays; Three-dimensional display; Crosstalk English 2023 2023-01-02 10.1080/15980316.2022.2136275 바로가기 바로가기 바로가기 바로가기
Article Structural and luminescence properties of transparent borate glass co-doped with Gd³⁺/Pr³⁺ for photonics application A new glass system of lithium borate doped with Gd2O3 and Pr2O3 has been fabricated using a conventional melt quenching technique. The physical parameters, such as density, molar volume, and refractive index, were measured and found to increase as the concentrations of lanthanide oxide (Gd2O3 and Pr2O3) in the glass increased, revealing the underlying structural changes. According to the results of XRD and FTIR, the synthesized glasses exhibited an amorphous structure, and borate complexes served as the triangular BO3, tetrahedral BO4, and OH group amounts in oxide glass. The photoluminescence (PL) spectra show characteristic emission bands resulting from f-f transitions of Pr3+ ions. The strongest emission occurred at 603 nm, corresponding to the transition from the 1D2 state to the 3H4 state. The optimal concentration of Gd2O3 for maximizing emission intensity was found to be 5.0 mol%, and this concentration will be used in the next experiment with varying Pr2O3 concentrations. In the subsequent experiment, emission spectra were recorded by exciting the glass with light at wavelengths of 445 nm, 469 nm, and 483 nm. The resulting emission spectra displayed the characteristic pattern associated with the emission of Pr3+. This emission peak at 603 nm represented the strongest intensity in the spectra, which is a common characteristic of Pr3+ emission. The emission intensity of the glasses initially increases with increasing concentrations of Pr2O3 up to 0.3 mol%, but beyond this concentration, the emission intensity starts to decrease. This behavior indicates the occurrence of a quenching effect at the 0.3 mol% concentration of Pr2O3. X-ray absorption near-edge structure (XANES) analysis confirmed that praseodymium ions were predominantly in the 3 + oxidation state. The chemical composition of the created glass was confirmed to be suitable for photonics applications. Manyum, P.; Rittisut, W.; Wantana, N.; Ruangtaweep, Y.; Rujirawat, S.; Kamonsuangkasem, K.; Yimnirun, R.; Prasatkhetragarn, A.; Intachai, N.; Kothan, S.; Kim, H. J.; Kaewkhao, J. Suranaree Univ Technol, Sch Phys, Ctr Excellence High Energy Phys & Astrophys, Nakhon Ratchasima 30000, Thailand; Nakhon Pathom Rajabhat Univ, Fac Sci & Technol, Phys Program, Nakhon Pathom 73000, Thailand; Nakhon Pathom Rajabhat Univ, Ctr Excellence Glass Technol & Mat Sci, Nakhon Pathom 73000, Thailand; Synchrotron Light Res Inst Publ Org, 111 Univ Ave, Nakhon Ratchasi 30000, Thailand; Vidyasirimedhi Inst Sci & Technol VISTEC, Sch Energy Sci & Engn, Rayong 21210, Thailand; Vidyasirimedhi Inst Sci & Technol VISTEC, Res Network NANOTEC VISTEC Nanotechnol Energy, Rayong 21210, Thailand; Univ Phayao, Sch Sci, Appl Sci Program, Phayao 56000, Thailand; Chiang Mai Univ, Fac Associated Med Sci, Ctr Radiat Res & Med Imaging, Dept Radiol Technol, Chiang Mai 50200, Thailand; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea Intachai, Nuttawadee/HOH-1735-2023; Kim, Hong Joo/AAE-1178-2022 6506891657; 57208675448; 56267058700; 37108588700; 6603107856; 55437015900; 24504594000; 23098474100; 57221909427; 6507017165; 59051568100; 23974520300 pmanyum@sut.ac.th;suchart.kothan@cmu.ac.th;jakrapong@webmail.npru.ac.th; MATERIALS TODAY COMMUNICATIONS MATER TODAY COMMUN 2352-4928 37 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY 2023 3.7 40.0 1.03 2025-06-25 10 10 Photoluminescence; Oxidation state OPTICAL-PROPERTIES; DY3+; ABSORPTION; EMISSION Gd<sub>2</sub>O<sub>3</sub> and Pr<sub>2</sub>O<sub>3</sub>; Oxidation state; Photoluminescence Emission spectroscopy; Fourier transform infrared spectroscopy; Gadolinium compounds; Glass; Lithium compounds; Praseodymium compounds; Quenching; Refractive index; Synthesis (chemical); X ray absorption; Borate glass; Co-doped; Emission spectrums; Emissions intensity; Gd2O3 and pr2O3; Glass systems; Luminescence properties; Melt quenching techniques; Oxidation state; Photonic application; Photoluminescence English 2023 2023-12 10.1016/j.mtcomm.2023.107078 바로가기 바로가기 바로가기 바로가기
Article Anatomical Consideration for Anterior Approach of Cervicothoracic Junction: A Computed Tomography Image Analysis Background: In the cervicothoracic junction (CTJ), there is limited working space to perform the posterior-only approach. Therefore, a combined anterior approach is required in some cases. However, the great vessels and sternum obstruct the anterior corridor and make the anterior approach difficult. We analyzed relevant anatomical structures encountered during the anterior approach in the CTJ and evaluated the feasibility of previously reported surgical corridors. Methods: We retrospectively examined 49 patients who underwent neck computed tomography angiography between January 2015 and May 2020. Using the coronal images, we measured the intercarotid artery angle (ICAA), intercarotid artery distance (ICAD), shape of the brachiocephalic trunk (BCT), and position of the BCT base. We then measured the most cranial level requiring manubriotomy for the anterior approach (ML), the most caudal level accessible through the superior corridor (SC), and the most caudal level through the inferior corridor (IC) according to the surgeon's line of sight using the sagittal axis image. Results: The mean ICAA and ICAD were 50.83 degrees +/- 15.23 degrees and 33.38 +/- 12.11 mm, respectively. Notably, BCT shape was of the convex type in most cases (42.9%), followed by the straight type (36.7%). In addition, the base of BCT was most commonly located inside the body (49%). Moreover, ICAA and ICAD were significantly greater in men. Although men mostly had the BCT base inside the body (64.3%), female mostly had it on the edge of the body (47.6%). Notably, ML showed the highest frequency (16.3%) in the T1 lower and upper bodies. Furthermore, through SC and IC, it was possible to approach the T4 lower body and T6 midbody, respectively. SC showed the highest frequency (16.3%) in the T3 lower body, and IC showed the highest frequency (20.4%) in the T5 midbody. Conclusions: ICAA and ICAD were larger and higher in men. BCT was convex and located inside the body in most cases. The accessible level of ML, SC, and IC were T1, T3, and T5, respectively. For the anterior approach in the CTJ, preoperative vascular and accessible level analysis of corridors is essential to decide on the appropriate corridor and reduce complications. Park, Eugene J.; Jeong, Bo-Gil; Min, Woo-Kie Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthoped Surg, 130 Dongdeok Ro, Daegu 41944, South Korea 55371642100; 58617976200; 8548041000 oswkmin@gmail.com; CLINICS IN ORTHOPEDIC SURGERY CLIN ORTHOP SURG 2005-291X 2005-4408 15 5 SCIE ORTHOPEDICS 2023 1.9 40.1 0 2025-06-25 0 0 Thoracic spine; Orthopedic procedures; Brachiocephalic trunk; Manubrium UPPER THORACIC SPINE; CERVICAL-SPINE; TUMORS Brachiocephalic trunk; Manubrium; Orthopedic procedures; Thoracic spine Cervical Vertebrae; Female; Humans; Male; Orthopedic Procedures; Retrospective Studies; Thoracic Vertebrae; Tomography, X-Ray Computed; adult; aged; Article; brachiocephalic trunk; cardiovascular parameters; clinical article; clinical evaluation; cohort analysis; computed tomographic angiography; computer assisted tomography; feasibility study; female; human; human cell; human tissue; image analysis; intercarotid artery angle; intercarotid artery distance; male; middle aged; retrospective study; spinal angiography; cervical vertebra; diagnostic imaging; orthopedic surgery; procedures; surgery; thoracic vertebra; x-ray computed tomography English 2023 2023-10 10.4055/cios22394 바로가기 바로가기 바로가기 바로가기
Review Current Research on the Influence of Statin Treatment on Rotator Cuff Healing Rotator cuff tears are a condition characterized by damage to the muscles and tendons that connect the scapula and humerus, which are responsible for shoulder rotation and arm lifting. Metabolic factors such as diabetes, thyroid disease, high cholesterol, vitamin D deficiency, obesity, and smoking have been associated with an increased risk of rotator cuff tears. Interestingly, patients with hyperlipidemia, a condition characterized by high levels of cholesterol and other fats in the blood, have been found to have a higher incidence of rotator cuff tears and breakdown of tendon matrix. As a result, statin therapy, which is commonly used to lower cholesterol levels in hyperlipidemia, has been explored as a potential treatment to improve clinical outcomes in rotator cuff tears. However, the results of preclinical and clinical studies on the effects of statins on tendon healing in rotator cuff tears are limited and not well-defined. Moreover, since hyperlipidemia and rotator cuff tears are more prevalent in older individuals, a literature review on the efficacy and safety of statin therapy in this population is needed. Yoon, Jong Pil; Park, Sung-Jin; Kim, Dong-Hyun; Shim, Bum-Jin; Chung, Seok Won Kyungpook Natl Univ Hosp, Dept Orthoped Surg, Daegu, South Korea; Konkuk Univ, Dept Orthopaed Surg, Med Ctr, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Orthoped Surg, 130 Dongdeok, Daegu 41944, South Korea 36098548400; 58527890700; 57198637188; 57201499293; 37065938600 knuhos_sh2@naver.com; CLINICS IN ORTHOPEDIC SURGERY CLIN ORTHOP SURG 2005-291X 2005-4408 15 6 SCIE ORTHOPEDICS 2023 1.9 40.1 1.01 2025-06-25 5 6 Statin; Rotator cuff; Tendon healing; Lipid-lowering therapy; Hyperlipidemia HYPERCHOLESTEROLEMIA; SIMVASTATIN; ATORVASTATIN; TENDON; HYPERLIPIDEMIA; MUSCLE; RISK; INFILTRATION; PRAVASTATIN; GUIDELINES Hyperlipidemia; Lipid-lowering therapy; Rotator cuff; Statin; Tendon healing Aged; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Rotator Cuff; Rotator Cuff Injuries; Treatment Outcome; atorvastatin; cyclooxygenase 2; hydroxymethylglutaryl coenzyme A reductase inhibitor; low density lipoprotein cholesterol; mevinolin; pravastatin; prostaglandin E2; rosuvastatin; silk fibroin; simvastatin; cholesterol; hydroxymethylglutaryl coenzyme A reductase inhibitor; antifibrotic activity; atherosclerotic plaque; drug megadose; drug safety; drug tolerability; familial hypercholesterolemia; human; hypercholesterolemia; hyperlipidemia; hypertransaminasemia; muscle strength; myalgia; myopathy; nonhuman; reoperation; Review; rhabdomyolysis; risk factor; rotator cuff repair; rotator cuff rupture; tendinitis; aged; hyperlipidemia; rotator cuff; rotator cuff injury; treatment outcome English 2023 2023-12 10.4055/cios23131 바로가기 바로가기 바로가기 바로가기
Article CyTOF analysis for differential immune cellular profiling between latent tuberculosis infection and active tuberculosis Limited data exist about the comparative immune cell population profile determined by cytometry by time-of -flight (CyTOF) analysis between active tuberculosis (TB) and latent TB infection (LTBI). In this study, we per-formed CyTOF analysis using peripheral blood mononuclear cells (PBMCs) to compare the differential immune cellular profile between active TB and LTBI. A total of 51 subjects (active TB [n = 34] and LTBI [n = 17]) were included. CyTOF analysis of 16 subjects (active TB [n = 8] and LTBI [n = 8]) identified a significantly higher Th17-like cell population in active TB than in LTBI. This finding was validated in the remaining 35 subjects (active TB [n = 26] and LTBI [n = 9]) using flow cytometry analysis, which consistently reveals a higher per-centage of Th17 cell population in active TB (p = 0.032). The Th1/Th17 ratio represented good ability to discriminate between active TB and LTBI (AUC = 0.812). Among patients with active TB, the Th17 cell per-centage was found to be lower in more advanced forms of the disease. Additionally, Th17 cell percentage positively correlated with the levels of IL-6 and neutrophil-lymphocyte ratio, respectively. In conclusion, CyTOF analysis of PBMCs showed a significantly higher percentage of Th17 cells in active TB although fairly similar immune cell populations between active TB and LTBI were observed. Kim, Chang Ho; Kim, Ha-Jeong; Park, Ji Eun; Lee, Yong Hoon; Ha Choi, Sun; Seo, Hyewon; Yoo, Seung Soo; Lee, Shin Yup; Cha, Seung Ick; Park, Jae Yong; Lee, Jaehee Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, BK21 Plus KNU Biomed Convergence Program,Dept Phys, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, 680 Gukchaebosang Ro, Daegu 700842, South Korea Park, Jinkyeong/GLV-1649-2022; Lee, You/T-6086-2019; Lee, Jaehee/S-1697-2018; Lee, Jun Young/CAI-2335-2022 7409873555; 57191717512; 57195437358; 57199022948; 57199723585; 55612130200; 56479781600; 49863712700; 35227126400; 58360293800; 13805476000 jaelee@knu.ac.kr; TUBERCULOSIS TUBERCULOSIS 1472-9792 1873-281X 140 SCIE IMMUNOLOGY;MICROBIOLOGY;RESPIRATORY SYSTEM 2023 2.8 40.1 0.33 2025-06-25 2 2 CyTOF; Tuberculosis; Latent; Th17; Flow cytometry T-CELLS; MYCOBACTERIUM-TUBERCULOSIS; TH17; CYTOMETRY CyTOF; Flow cytometry; Latent; Th17; Tuberculosis Flow Cytometry; Humans; Latent Tuberculosis; Leukocytes, Mononuclear; Mycobacterium tuberculosis; Tuberculosis; CD3 antigen; CD4 antigen; CD8 antigen; chemokine receptor CCR4; chemokine receptor CCR6; chemokine receptor CXCR3; gamma interferon; interleukin 10; interleukin 2; interleukin 6; transforming growth factor beta; tumor necrosis factor; adult; Article; CD8+ T lymphocyte; cell population; cellular immunity; controlled study; female; flow cytometry; human; immune response; immunocompetent cell; latent tuberculosis; lung tuberculosis; major clinical study; male; neutrophil lymphocyte ratio; peripheral blood mononuclear cell; prospective study; receiver operating characteristic; Th1 cell; Th17 cell; time of flight mass spectrometry; tuberculosis; flow cytometry; latent tuberculosis; mononuclear cell; Mycobacterium tuberculosis English 2023 2023-05 10.1016/j.tube.2023.102344 바로가기 바로가기 바로가기 바로가기
Article Outcomes of Angular Stable Locking System in Femoral Diaphyseal Fractures of Elderly Patients: A Multicenter Comparative Study Background: The angular stable locking system (ASLS) was developed to provide additional stability to the distal interlocking screw of the intramedullary (IM) nail. Effects of ASLS on the treatment of femoral diaphyseal fractures in the elderly remain un-known. The aim of this study was to compare radiological outcomes of IM nailing using ASLS screws to IM nails with conventional interlocking screws in elderly patients with femoral shaft fractures. Methods: A multicenter retrospective review of 129 patients (average age, 73.5 years; 98 women and 31 men) aged 65 years or older who underwent IM nail fixation for femoral diaphyseal fractures (AO/Orthopaedic Trauma Association [OTA] classification 32) was conducted. Demographic information of patients, fracture site (subtrochanteric or shaft), fracture type (traumatic or atypical), and AO/OTA fracture classification were investigated. Reduction status was evaluated by postoperative plain radiography. Pres-ence of union and time to union were evaluated through serial plain radiograph follow-up. Reoperation due to nonunion or implant failure was also evaluated. Results: ASLS was used in 65 patients (50.3%). A total of 118 patients (91.5%) achieved union without additional surgery and the mean union time was 31.8 +/- 13.0 weeks. In terms of reduction status, angulation was greater in the group using ASLS. There were no statistically significant differences of union rate, time to union, and reoperation rate according to the use of ASLS (p > 0.05). There was no difference in the outcomes according to the use of ASLS even when the analysis was divided in terms of fracture site or fracture type (p > 0.05). In further subgroup analysis, only the traumatic subtrochanteric area group showed statistically sig-nificantly shorter time to union when ASLS was used (p = 0.038). Conclusions: In geriatric patients with femoral diaphyseal fractures, the use of ASLS was not considered to have a significant effect on fracture healing. Fracture healing seemed to be more affected by surgical techniques such as minimizing the gap and fracture characteristics such as atypical femoral fractures, rather than implants. Hwang, Kyu Tae; Kook, Incheol; Lee, Jae-Ho; Oh, Chang-Wug; Sohn, Oog-Jin; Kim, Ji Wan; Park, Ki-Chul Hanyang Univ Hosp, Dept Orthopaed Surg, Seoul, South Korea; Hanyang Univ, Dept Orthopaed Surg, Guri Hosp, Guri, South Korea; Kyungpook Natl Univ Hosp, Dept Orthopaed Surg, Daegu, South Korea; Yeungnam Univ, Dept Orthopaed Surg, Med Ctr, Daegu, South Korea; Univ Ulsan, Asan Med Ctr, Dept Orthopaed Surg, Coll Med, Seoul, South Korea; Hanyang Univ, Dept Orthopaed Surg, Guri Hosp, 153 Gyeongchun ro, Guri 11923, South Korea ; Hwang, Kyu/R-7249-2016; Oh, Chang-Wug/AAO-4602-2021; Hwang, Kyu Tae/R-7249-2016 35336689700; 58263258100; 57200821240; 22135834200; 14043970900; 55898554400; 56062454500 kcpark@hanyang.ac.kr; CLINICS IN ORTHOPEDIC SURGERY CLIN ORTHOP SURG 2005-291X 2005-4408 15 3 SCIE ORTHOPEDICS 2023 1.9 40.1 0.87 2025-06-25 0 3 Femoral shaft; Traumatic fracture; Atypical fracture; Angular stable locking system; Intramedullary nail INTRAMEDULLARY NAILS; SHAFT FRACTURES; STABILITY; FIXATION; FEMUR; EPIDEMIOLOGY; MOVEMENTS Angular stable locking system; Atypical fracture; Femoral shaft; Intramedullary nail; Traumatic fracture Aged; Bone Nails; Female; Femoral Fractures; Fracture Fixation, Intramedullary; Fracture Healing; Humans; Male; Reoperation; Retrospective Studies; Treatment Outcome; aged; Article; bone radiography; comparative study; controlled study; demographics; device failure; female; femoral shaft; femur diaphysis; femur fracture; femur shaft fracture; femur subtrochanteric fracture; fracture healing; fracture nonunion; geriatric patient; human; intramedullary nailing; major clinical study; male; outcome assessment; postoperative monitoring; radiological parameters; reoperation; retrospective study; surgical technique; clinical trial; diagnostic imaging; multicenter study; procedures; treatment outcome English 2023 2023-06 10.4055/cios22215 바로가기 바로가기 바로가기 바로가기
Article The Impact of C-Reactive Protein-To-Albumin Ratio on Mortality in Patients with Acute Kidney Injury Requiring Continuous Renal Replacement Therapy: A Multicenter Retrospective Study Introduction: C-reactive protein-to-albumin ratio (CAR) is a prognostic marker in various diseases that represents patients' inflammation and nutritional status. Here, we aimed to investigate the prognostic value of CAR in critically ill patients with severe acute kidney injury requiring continuous renal replacement therapy (CRRT). Methods: We retrospectively collected data from eight tertiary hospitals in Korea from 2006-2021. The patients were divided into quartiles according to CAR levels at the time of CRRT initiation. Cox regression analyses were performed to investigate the effect of CAR on in-hospital mortality. The mortality prediction performance of CAR was evaluated using the area under the curve (AUC), net reclassification improvement (NRI), and integrated discrimination improvement (IDI). Results: In total, 3,995 patients who underwent CRRT were included, and the in-hospital mortality rate was 67.3% during the follow-up period. The 7-day, 30-day, and inhospital mortality rates increased toward higher CAR quartiles (all p < 0.001). After adjusting for confounding variables, the higher quartile groups had an increased risk of in-hospital mortality (quartile 3: adjusted hazard ratio [aHR], 1.26, 95% confidence interval [CI], 1.10-1.43, p < 0.001; quartile 4: aHR, 1.22, 95% CI, 1.07-1.40, p = 0.003). CAR combined with Acute Physiology and Chronic Health Evaluation II or Sequential Organ Failure Assessment scores significantly increased the predictive power compared to each severity score alone for AUC, NRI, and IDI (all p < 0.05). Conclusions: A high CAR is associated with increased inhospital mortality in critically ill patients requiring CRRT. The combined use of CAR and severity scores provides better predictive performance for mortality than the severity score alone. © 2023 S. Karger AG, Basel. Jeon, You Hyun; Lee, Sung Woo; Jeon, Yena; Cho, Jang-Hee; Jung, Jiyun; Lee, Jangwook; Park, Jae Yoon; Kim, Yong Chul; Ban, Tae Hyun; Park, Woo Yeong; Kim, Kipyo; Kim, Hyosang; Kim, Kyeong Min; Lim, Jeong-Hoon Division of Nephrology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea; Department of Internal Medicine, Uijeongbu Eulji University Medical Center, Uijeongbu, South Korea; Department of Statistics, Kyungpook National University, Daegu, South Korea; Division of Nephrology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea; Data Management and Statistics Institute, Dongguk University Ilsan Hospital, Goyang, South Korea, Research Center for Chronic Disease and Environmental Medicine, Dongguk University College of Medicine, Gyeongju, South Korea; Research Center for Chronic Disease and Environmental Medicine, Dongguk University College of Medicine, Gyeongju, South Korea, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, South Korea; Research Center for Chronic Disease and Environmental Medicine, Dongguk University College of Medicine, Gyeongju, South Korea, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, South Korea, Department of Internal Medicine, Dongguk University College of Medicine, Gyeongju, South Korea; Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea; Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Daegu, South Korea; Department of Internal Medicine, Inha University School of Medicine, Incheon, South Korea; Division of Nephrology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Internal Medicine, Daejeon Eulji University Hospital, College of Medicine, Eulji University, Daejeon, South Korea; Division of Nephrology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea 57820096000; 56708181900; 57209909350; 7403536291; 57211813518; 57223232128; 56603383500; 57026583000; 56119751700; 36344980100; 57164118000; 57190118848; 57199438486; 55360244300 jh-lim@knu.ac.kr;km1209@eulji.ac.kr; Nephron NEPHRON 1660-8151 2235-3186 148 6 SCIE UROLOGY & NEPHROLOGY 2023 2.3 40.1 1.04 2025-06-25 5 Acute kidney injury; C-reactive protein-to-albumin ratio; Continuous renal replacement therapy; Critical care; Mortality Acute Kidney Injury; Aged; C-Reactive Protein; Continuous Renal Replacement Therapy; Critical Illness; Female; Hospital Mortality; Humans; Male; Middle Aged; Prognosis; Republic of Korea; Retrospective Studies; Serum Albumin; albumin; C reactive protein; hypertensive agent; C reactive protein; serum albumin; acute kidney failure; aged; analytical parameters; APACHE; Article; artificial ventilation; C-reactive protein-to-albumin ratio; chronic obstructive lung disease; cohort analysis; continuous renal replacement therapy; controlled study; critically ill patient; female; follow up; human; in-hospital mortality; injury severity; Korea; leukemia; major clinical study; male; metastasis; mortality rate; mortality risk; multicenter study (topic); nutritional status; predictive value; prognosis; reference value; retrospective study; sepsis; Sequential Organ Failure Assessment Score; tertiary care center; acute kidney failure; blood; clinical trial; critical illness; epidemiology; hospital mortality; metabolism; middle aged; mortality; multicenter study; prognosis; South Korea; therapy English Final 2023 10.1159/000534970 바로가기 바로가기 바로가기
Article An Advanced Multiplex Real-Time Reverse Transcription Loop-Mediated Isothermal Amplification Assay for Rapid and Reliable Detection of Porcine Epidemic Diarrhea Virus and Porcine Internal Positive Control For rapid and reliable detection of porcine epidemic diarrhea virus (PEDV) from pig clinical samples, a multiplex, real-time, reverse transcription loop-mediated isothermal amplification (mqRT-LAMP) was developed using two sets of primers and assimilating probes specific to the PEDV N gene and the Sus scrofa beta-actin gene, which was used as an endogenous internal positive control (EIPC) to avoid false-negative results. The assay specifically amplified both target genes of PEDV and EIPC in a single reaction without any interference but did not amplify other porcine viral nucleic acids. The limit of detection was 10 copies/mu L, 100-fold lower than that of a reverse transcription-polymerase chain reaction (RT-PCR) and equivalent to that of quantitative/real-time RT-PCR (qRT-PCR). This assay has high repeatability and reproducibility with coefficients of variation < 4.0%. The positive signal of the mqRT-LAMP assay was generated within 25 min, demonstrating advantages in rapid detection of PEDV over RT-PCR or qRT-PCR assay, which require at least 2 h turnaround times. In clinical evaluation, the detection rate of PEDV by mqRT-LAMP assay (77.3%) was higher than that of RT-PCR assay (69.7%), and comparable to qRT-PCR (76.8%) with almost 100% concordance (kappa value 0.98). The developed mqRT-LAMP assay can serve as an advanced alternative method for PEDV diagnosis because it has high sensitivity and specificity, rapidity, and reliability even in resource-limited laboratories. Kim, Hye-Ryung; Kim, Jong-Min; Baek, Ji-Su; Park, Jonghyun; Ku, Bok Kyung; Kim, Won-Il; Jeoung, Hye-Young; Lee, Kyoung-Ki; Park, Choi-Kyu Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Vet Biomed Sci, Daegu 41566, South Korea; Jeonbuk Natl Univ, Coll Vet Med, Iksan 54596, South Korea; Anim & Plant Quarantine Agcy, Gimcheon Si 39660, Gyeongsangbuk D, South Korea 57195772612; 57277964700; 58111837700; 57210160562; 55730056800; 9745131200; 54924137400; 38163138800; 24768064900 gpfuddl25@knu.ac.kr;kjm51062@knu.ac.kr;sy20103712@knu.ac.kr;parkjh@knu.ac.kr;kubk@korea.kr;kwi0621@jbnu.ac.kr;jhy98@korea.kr;naturelkk@korea.kr;parkck@knu.ac.kr; VIRUSES-BASEL VIRUSES-BASEL 1999-4915 15 11 SCIE VIROLOGY 2023 3.8 40.2 0.57 2025-06-25 3 3 PEDV; multiplex real-time RT-LAMP; assimilating probe; N gene; Sus scrofa beta-actin gene; internal positive control POLYMERASE-CHAIN-REACTION; TRANSMISSIBLE GASTROENTERITIS VIRUS; STOOL SPECIMENS; PCR; LAMP; STRAINS; GUIDELINES; DIAGNOSIS; PEDV assimilating probe; internal positive control; multiplex real-time RT-LAMP; N gene; PEDV; Sus scrofa β-actin gene Animals; Coronavirus Infections; LAMP assay; Nucleic Acid Amplification Techniques; Porcine epidemic diarrhea virus; Reproducibility of Results; Reverse Transcription; Sensitivity and Specificity; Swine; Swine Diseases; beta actin; Sus scrofa beta actin; unclassified drug; agar gel electrophoresis; Article; bioinformatics; Classical swine fever virus; clinical evaluation; controlled study; cycle threshold value; diagnostic test accuracy study; DNA extraction; DNA sequence; false negative result; Foot and mouth disease virus; gene expression; gene sequence; limit of detection; loop mediated isothermal amplification; measurement accuracy; measurement repeatability; multiplex real time polymerase chain reaction; multiplex reverse transcription polymerase chain reaction; nonhuman; Porcine circovirus 2; Porcine epidemic diarrhea virus; porcine internal positive control; Porcine parvovirus; porcine rotavirus; real time reverse transcription polymerase chain reaction; reliability; reproducibility; RNA transcription; Sanger sequencing; sensitivity and specificity; tissue microarray; turnaround time; virus replication; virus transmission; animal; Coronavirus infection; genetics; loop mediated isothermal amplification; nucleic acid amplification techniques; pig; procedures; reverse transcription; swine disease; veterinary medicine English 2023 2023-11 10.3390/v15112204 바로가기 바로가기 바로가기 바로가기
Article Ferromagnetic chloro-bridged copper(II) coordination polymer: Synthesis, structure, magnetism, and DNA cleavage effects A new coordination polymer, [Cu(pmaeOH)Cl-2](n), based on the copper(II) ion and 2-(2-pyridine-2-ylmethylamino)ethanol (pmaeOH) ligand was obtained from a methanol solution. The coordination polymer was characterized by elemental analysis, infrared spectroscopy, X-ray single-crystal diffraction, magnetic susceptibility measurements, and DNA cleavage effect. The crystal structure of the polymer consisted of a one-dimensional (1-D) chain with each copper(II) atom six-coordinated (by three nitrogen atoms and three chlorine atoms) in a severely distorted octahedral geometry. The polymer exhibited ferromagnetic behavior within the 1-D chain (J = 6.35 cm(-1)) through the long bond distances of copper(II) and chloride ions. The copper(II) complex cleaves scDNA through oxidative pathways, where the reactive oxygen species (ROS) involved in DNA cleavage are the superoxide radical (center dot O-2(-)), singlet oxygen (O-1(2)), and hydrogen peroxide (H2O2). This paper reports the new synthesis of a ferromagnetically coupled polymer bridged with a chloride ion and its DNA cleavage effect for molecular memory devices and DNA repair applications. (C) 2022 Elsevier B.V. All rights reserved. Jang, Yoon Jung; Han, Ji Hoon; Min, Kil Sik Yeungnam Univ, Coll Basic Educ, Gyongsan 38541, Gyeongbuk, South Korea; Andong Natl Univ, Dept Appl Chem, Andong 36729, South Korea; Kyungpook Natl Univ, Dept Chem Educ, Daegu 41566, South Korea Jang, Yoon/Z-1136-2019 7201869031; 57194237504; 7201466885 minks@knu.ac.kr; JOURNAL OF MOLECULAR STRUCTURE J MOL STRUCT 0022-2860 1872-8014 1271 SCIE CHEMISTRY, PHYSICAL 2023 4 40.2 0.7 2025-06-25 4 5 Copper(II) ion; Coordination polymer; Structure; Magnetic properties; DNA cleavage HIGH-TEMPERATURE-SERIES; CRYSTAL-STRUCTURES; CU(II) COMPLEXES; HYDROGEN-BONDS; LIGANDS Coordination polymer; Copper(II) ion; DNA cleavage; Magnetic properties; Structure Atoms; Chlorine compounds; Coordination reactions; Copper compounds; Crystal atomic structure; DNA; Ferromagnetic materials; Ferromagnetism; Infrared spectroscopy; Magnetic susceptibility; Oxygen; Single crystals; 1D chain; 2 pyridines; Chloride ions; Coordination Polymers; Coordination-polymers; Copper(II) ion; DNA cleavage; Ferromagnetics; Polymer synthesis; Pyridine-2; Ions English 2023 2023-01-05 10.1016/j.molstruc.2022.134136 바로가기 바로가기 바로가기 바로가기
Article First Detection and Genetic Characterization of Swine Orthopneumovirus from Domestic Pig Farms in the Republic of Korea Novel swine orthopneumovirus (SOV) infections have been identified in pigs in the USA and some European countries but not in Asian countries, including South Korea, to date. The current study reports the first SOV infections in four domestic pig farms located in four provinces across South Korea. The detection rate of SOV in oral fluid samples using qRT-PCR was 4.4% (14/389), indicating the presence of the virus in pigs at commercial farms in Korea. Two complete genome sequences and one glycoprotein (G) gene sequence were obtained from SOV-positive samples. The complete genome analysis of KSOV-2201 and KSOV-2202 strains showed 98.2 and 95.4% homologies with a previously reported SOV, and the phylogenetic tree exhibited a high correlation with a previously reported SOV strain from the US and a canine pneumovirus (CPnV) strain from China. Based on the genetic analysis of the viral G gene, the murine pneumonia virus (MPV)-like orthopneumoviruses (MLOVs) were divided into two genogroups (G1 and G2). Seventeen CPnVs and two feline pneumoviruses were grouped into G1, while the Korean SOV strains identified in this study were grouped into G2 along with one SOV and two CPnVs. These results will contribute to expanding our understanding of the geographical distribution and genetic characteristics of the novel SOV in the global pig population. Park, Jonghyun; Kim, Hye-Ryung; Lee, Eon-Bee; Lee, Sang-Kwon; Kim, Won-Il; Lyoo, Young S.; Park, Choi-Kyu; Ku, Bok Kyung; Jeoung, Hye-Young; Lee, Kyoung-Ki; Park, Seung-Chun Kyungpook Natl Univ, Inst Anim Biomed Sci, Coll Vet Med, Lab Vet Pharmacokinet & Pharmacodynam, 80 Daehak Ro, Daegu 41566, South Korea; DIVA Bio Inc, Daegu 41519, South Korea; Kyungpook Natl Univ, Coll Vet Med, Inst Vet Biomed Sci, Daegu 41566, South Korea; Jeonbuk Natl Univ, Coll Vet Med, 79 Gobong Ro, Iksan 54596, South Korea; Konkuk Univ, Coll Vet Med, 120 Neungdong Ro, Seoul 05029, South Korea; Anim & Plant Quarantine Agcy, Gimcheon 39660, South Korea ; Lee, Sang-Kwon/IYI-9991-2023; Park, Seung-Chun/AAV-3388-2021; Lee, Jung Bok/HHZ-3200-2022 57210160562; 57195772612; 57216526135; 56494541400; 55730056800; 35501431200; 24768064900; 9745131200; 54924137400; 38163138800; 7501832396 parkjh@knu.ac.kr;gpfuddl25@knu.ac.kr;eonbee@gmail.com;sklee10@knu.ac.kr;kwi0621@jbnu.ac.kr;lyoo@konkuk.ac.kr;parkck@knu.ac.kr;kubk@korea.kr;jhy98@korea.kr;naturelee@korea.kr;parksch@knu.ac.kr; VIRUSES-BASEL VIRUSES-BASEL 1999-4915 15 12 SCIE VIROLOGY 2023 3.8 40.2 0.19 2025-06-25 1 1 genome sequencing; phylogenetic analysis; swine orthopneumovirus; pneumovirus genome sequencing; phylogenetic analysis; pneumovirus; swine orthopneumovirus Animals; Cats; Dogs; Farms; Mice; Phylogeny; Pneumovirus; Republic of Korea; Respiratory Syncytial Viruses; Sus scrofa; Swine; Swine Diseases; Article; bioinformatics; DNA sequence; domestic pig; gene sequence; genetic analysis; genome analysis; Human respiratory syncytial virus; Korea; metagenomics; Murine pneumonia virus; nonhuman; phylogeny; Pneumovirus; Porcine circovirus 2; prevalence; reverse transcription polymerase chain reaction; RNA extraction; sequence analysis; sequence homology; virus genome; virus isolation; virus transmission; whole genome sequencing; agricultural worker; animal; cat; dog; mouse; pig; South Korea; swine disease English 2023 2023-12 10.3390/v15122371 바로가기 바로가기 바로가기 바로가기
Article Insights into the inhibitory activity and mechanism of action of flavonoids from the stems and branches of Acer mono Maxim. against ?-glucosidase via kinetic analysis, molecular docking, and molecular dynamics simulations Acer mono Maxim. (mono maple), a deciduous tree found in temperate regions, has been reported to have a variety of pharmacological properties, including antioxidant, hepatoprotective, and osteoclastogenesis-inhibitory effects. However, the potential mechanism by which secondary metabolites inhibit alpha- glucosidase activity has not been investigated. In this study, 12 flavonoids (1 -12) were isolated from the stems and branches of A. mono Maxim. and structurally elucidated using modern spectroscopic tech-niques. The inhibitory activity and mechanism of action of the isolated flavonoids against alpha-glucosidase were studied through in vitro assays, enzyme kinetic analysis, molecular docking, and molecular dynamics simulations. Among all test compounds, two dimeric flavan-3-ols (1 and 2) exhibited strong alpha-glucosidase inhibitory effect, with IC50 values of 49.69 and 48.80 mu M, respectively, and showed non-competitive inhi-bition of alpha-glucosidase. The findings observed from in vitro and in silico studies suggests that two active compounds, 1 and 2, may be appropriate for future research into the development of new alpha-glucosidase inhibitors.(c) 2023 Elsevier B.V. All rights reserved. Phong, Nguyen Viet; Yang, Seo Young; Min, Byung Sun; Kim, Jeong Ah Kyungpook Natl Univ, Coll Pharm, Vessel Organ Interact Res Ctr, VOICE MRC, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Pharm, FOUR Community Based Intelligent Novel Drug Discov, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu 41566, South Korea; Sangji Univ, Dept Pharmaceut Engn, Wonju 26339, South Korea; Daegu Catholic Univ, Coll Pharm, Drug Res & Dev Ctr, Gyeongbuk 38430, South Korea; Daegu Catholic Univ, Coll Pharm, Gyeongbuk 38430, South Korea; Kyungpook Natl Univ, Coll Pharm, Daegu 41566, South Korea Nguyen, Viet Phong/AAQ-4207-2021 57205196739; 57215036954; 55663638200; 24722570900 bsmin@cu.ac.kr;jkim6923@knu.ac.kr; JOURNAL OF MOLECULAR STRUCTURE J MOL STRUCT 0022-2860 1872-8014 1282 SCIE CHEMISTRY, PHYSICAL 2023 4 40.2 2.24 2025-06-25 15 16 Acer mono Maxim; Flavonoid; ? -glucosidase; Kinetic analysis; Molecular docking; Molecular dynamics ALPHA-GLUCOSIDASE; DRYOPTERIS-CRASSIRHIZOMA; STILBENE GLYCOSIDES; PHLOROGLUCINOLS; IDENTIFICATION; DERIVATIVES; FLAVANONES; RHIZOMES; MAPLE Acer mono Maxim.; Flavonoid; Kinetic analysis; Molecular docking; Molecular dynamics; α-glucosidase Flavonoids; Kinetics; Metabolites; Molecular modeling; Acer mono maxim.; Dynamics simulation; Flavonoid; Glucosidase; Inhibitory activity; Inhibitory mechanism; Kinetic analysis; Mechanism of action; Molecular docking; Α-glucosidase; Molecular dynamics English 2023 2023-06-15 10.1016/j.molstruc.2023.135188 바로가기 바로가기 바로가기 바로가기
Article Performance and interaction mechanism of a new highly efficient benzimidazole-based epoxy resin for corrosion inhibition of carbon steel in HCl: A study based on experimental and first-principles DFTB simulations Thanks to their excellent properties, epoxy resins are the first choice for many engineering applications. In this regard, herein, a new epoxy resin, namely 1-(oxiran-2-ylmethyl-1H-benzo[d]imidazole (BIZ epoxy), was synthesized and characterized by nuclear magnetic resonance (1H, 13C NMR) and Fourier trans -form infrared-attenuated total reflection (FTIR-ATR)) techniques. The corrosion inhibition properties of prepared epoxy resin for carbon steel (CS) in 1.0 mol/L HCl were evaluated using electrochemical and scanning electron microscope (SEM) techniques. Furthermore, reactivity and interaction mechanisms be-tween epoxy resin molecule and the iron surface were investigated using quantum chemical parameters (QCPs) and Density-Functional Tight-Binding (DFTB). Electrochemical studies by potentiodynamic polar-ization curves (PPC) and electrochemical impedance spectroscopy (EIS) showed that the BIZ epoxy acted as a barrier against the acid corrosion of CS with an inhibition efficiency of 93 % at 1 mmol/L. The ad-sorption of BIZ epoxy followed the Langmuir adsorption isotherm and was found to be a physicochemical process. The SEM analysis showed a significant difference in surface morphology of CS after inhibition due to the formation of a protective barrier. DFTB simulation of BIZ epoxy - Fe(110) surface revealed the formation of a chemical bond and several long-range van der Waals interactions. The projected density of states (PDOS) of isolated and adsorbed systems confirmed the physicochemical nature of interactions between inhibitor molecule and Fe(110) surface.(c) 2022 Elsevier B.V. All rights reserved. Damej, M.; Molhi, A.; Lgaz, H.; Hsissou, R.; Aslam, J.; Benmessaoud, M.; Rezki, N.; Lee, H-S.; Lee, D-E. Mohammed V Univ Rabat, High Sch Technol, Environm Mat & Sustainable Dev Team CERNE2D, Rabat, Morocco; Hanyang Univ ERICA, Innovat Durable Bldg & Infrastruct Res Ctr, Ctr Creat Convergence Educ, 55 Hanyangdaehak Ro, Ansan 15588, Gyeonggi Do, South Korea; Ibn Tofail Univ, Lab Organ Chem Catalyst & Environm, Fac Sci, PO 242, Kenitra 14000, Morocco; Taibah Univ, Coll Sci, Dept Chem, Yanbu 30799, Saudi Arabia; Taibah Univ, Dept Chem, 30002, Al Madina Al Mounawara, Saudi Arabia; Hanyang Univ ERICA, Dept Architectural Engn, 1271 Sa 3 Dong, Ansan 15588, South Korea; Kyungpook Natl Univ, Sch Architecture Civil Environm & Energy Engn, 80 Daehak Ro, Daegu 41566, South Korea; Hanyang Univ, Dept Architectural Engn, Ansan 15588, South Korea HSISSOU, Rachid/C-1032-2018; Molhi, Abdu Ahmed/ITV-6074-2023; Hsissou, Rachid/C-1032-2018; Lee, HanSeung/E-9087-2013; Aslam, Jeenat/ABG-9277-2020; Lgaz, Hassane/U-9805-2019; Lee, Han-Seung/E-9087-2013; damej, mohamed/ABC-5889-2021 57151492700; 57222158456; 56707358100; 57193233249; 55342653000; 57151142600; 12770220800; 57956643400; 56605563300 hlgaz@hanyang.ac.kr;dolee@knu.ac.kr; JOURNAL OF MOLECULAR STRUCTURE J MOL STRUCT 0022-2860 1872-8014 1273 SCIE CHEMISTRY, PHYSICAL 2023 4 40.2 5.6 2025-06-25 35 41 Corrosion inhibitor; Carbon steel; Epoxy resin; Benzimidazole; Density of states MILD-STEEL; SURFACE; RESISTANCE; EXTRACT; ALLOY; IRON Benzimidazole; Carbon steel; Corrosion inhibitor; Density of states; Epoxy resin Chlorine compounds; Electrochemical corrosion; Electrochemical impedance spectroscopy; Epoxy resins; Fourier transform infrared spectroscopy; Infrared reflection; Molecules; Morphology; Nuclear magnetic resonance; Physicochemical properties; Quantum chemistry; Scanning electron microscopy; Steel corrosion; Surface morphology; Van der Waals forces; Benzimidazoles; Corrosion inhibition; Densities of state; Density-functional tight-binding; Epoxy; First principles; Interaction mechanisms; Performance; Property; Scanning electrons; Corrosion inhibitors English 2023 2023-02-05 10.1016/j.molstruc.2022.134232 바로가기 바로가기 바로가기 바로가기
Article DssPyLib: An open-source python FEM software to solve Poisson equation in 2-D using distributed source scheme This paper introduces DssPyLib, an open-source Python software to compute 2-D electrostatic and magnetostatic fields using the finite element method. With a minimalist interface and non-overlapping simple shapes, the software supports integral and finite element numerical solutions for open boundary problems. The software also provides numerical solutions using Distributed Source Scheme, a technique to reduce error around the sources of the field. An overview of the structure and features of DssPyLib is presented along with experimental validation. The software also features extraction of valuable information such as vector field at any point and force on any field source. The software explores various sources of errors and the methods to reduce errors in numerical simulations. (c) 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Goona, Nithin Kumar; Naik, Shraddha M.; Parne, Saidi Reddy; Paul, Anand Natl Inst Technol Goa, Dept Appl Sci, Ponda 403401, Goa, India; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu 41566, South Korea Naik, Shraddha/AAX-9472-2020; Paul, Anand/V-6724-2017; PARNE, SAIDI/ACZ-3648-2022 57219620061; 57200942684; 37049313200; 56650522400 nithin.goona@gmail.com;nithingoona@nitgoa.ac.in; SOFTWAREX SOFTWAREX 2352-7110 21 SCIE COMPUTER SCIENCE, SOFTWARE ENGINEERING 2023 2.4 40.5 0.11 2025-06-25 1 1 Finite element method; Integral method; Poisson equation; Python; Numerical solution; Dirichlet boundary condition FINITE-DIFFERENCE METHOD; ACCURACY Dirichlet boundary condition; Finite element method; Integral method; Numerical solution; Poisson equation; Python Boundary conditions; Finite element method; High level languages; Numerical methods; Numerical models; Open source software; Open systems; Poisson equation; Dirichlet boundary condition; Distributed sources; Experimental validations; Integral method; Magnetostatic field; Numerical solution; Open boundary problems; Open-source; Simple++; Software support; Python English 2023 2023-02 10.1016/j.softx.2023.101308 바로가기 바로가기 바로가기 바로가기
Article High-resolution 3D winds derived from a modified WISSDOM synthesis scheme using multiple Doppler lidars and observations The WISSDOM (Wind Synthesis System using Doppler Measurements) synthesis scheme was developed to derive high-resolution 3-dimensional (3D) winds under clear-air conditions. From this variational-based scheme, detailed wind information was obtained from scanning Doppler lidars, automatic weather stations (AWSs), sounding observations, and local reanalysis datasets (LDAPS, Local Data Assimilation and Prediction System), which were utilized as constraints to minimize the cost function. The objective of this study is to evaluate the performance and accuracy of derived 3D winds from this modified scheme. A strong wind event was selected to demonstrate its performance over complex terrain in Pyeongchang, South Korea. The size of the test domain is 12x12 km(2) extended up to 3 km a.m.s.l. (above mean sea level) height with a remarkably high horizontal and vertical resolution of 50 m. The derived winds reveal that reasonable patterns were explored from a control run, as they have significant similarity with the sounding observations. The results of intercomparisons show that the correlation coefficients between derived horizontal winds and sounding observations are 0.97 and 0.87 for u- and nu-component winds, respectively, and the averaged bias (root mean square deviation, RMSD) of horizontal winds is between -0.78 and 0.09 (1.77 and 1.65) m s(-1). The correlation coefficients between WISSDOM-derived winds and lidar QVP (quasi-vertical profile) are 0.84 and 0.35 for u- and v-component winds, respectively, and the averaged bias (RMSD) of horizontal winds is between 2.83 and 2.26 (3.69 and 2.92) m s(-1). The statistical errors also reveal a satisfying performance of the retrieved 3D winds; the median values of wind directions are -5 to 5 (0 to 2.5)degrees, the wind speed is approximately -1 to 3 m s(-1) (-1 to 0.5 m s(-1)), and the vertical velocity is -0.2 to 0.6 m s-1 compared with the lidar QVP (sounding observations). A series of sensitivity tests with different weighting coefficients, radius of influence (RI) in interpolation, and various combination of different datasets were also performed. The results indicate that the present setting of the control run is the optimal reference to WISSDOM synthesis in this event and will help verify the impacts against various scenarios and observational references in this area. Tsai, Chia-Lun; Kim, Kwonil; Liou, Yu-Chieng; Lee, GyuWon Kyungpook Natl Univ, Ctr Atmospher REmote sensing CARE, Dept Astron & Atmospher Sci, Daegu Gwangyeogsi, South Korea; Natl Cent Univ, Dept Atmospher Sci, Jhongli, Taiwan; Chinese Culture Univ, Dept Atmospher Sci, Taipei, Taiwan ; Tsai, Chia-Lun/AHI-4361-2022; Kim, Kwonil/HTN-0103-2023; Liou, Yu-Chieng/H-5178-2012 55474132500; 57191964318; 7102949463; 7404852271 gyuwon@knu.ac.kr; ATMOSPHERIC MEASUREMENT TECHNIQUES ATMOS MEAS TECH 1867-1381 1867-8548 16 3 SCIE METEOROLOGY & ATMOSPHERIC SCIENCES 2023 3.2 40.5 1.32 2025-06-25 8 8 IMMERSED BOUNDARY METHOD; COMPLEX TERRAIN; RADAR OBSERVATIONS; SINGLE-DOPPLER; KINEMATIC STRUCTURE; PART I; FLOW; PRECIPITATION; RETRIEVAL; MODEL Kangwon; Pyeongchang; South Korea; accuracy assessment; Doppler lidar; interpolation; observational method; three-dimensional modeling English 2023 2023-02-16 10.5194/amt-16-845-2023 바로가기 바로가기 바로가기 바로가기
Article Primary and additional treatment preference in aggressive retinopathy of prematurity and type 1 retinopathy of prematurity Objective This study aimed to evaluate the preference for antivascular endothelial growth factor (anti-VEGF) versus laser ablation therapy as primary and additional treatment in aggressive retinopathy of prematurity (ROP) and type 1 ROP. Methods This multicentre retrospective study was conducted at nine medical centres across South Korea. A total of 94 preterm infants with ROP who underwent primary treatment between January 2020 and December 2021 were enrolled. All eyes were classified as having type 1 ROP or aggressive ROP. Data on the zone, primary treatment chosen, injection dose, presence of reactivation and additional treatment were collected and analysed. Results Seventy infants (131 eyes) with type 1 ROP and 24 infants (45 eyes) with aggressive ROP were included. Anti-VEGF injection was selected as the primary treatment in 74.05% of the infants with type 1 ROP and 88.89% with aggressive ROP. Anti-VEGF injection was selected as the ROP was located in zone I or posterior zone II, and laser ablation was selected when it was located in zone II. The anti-VEGF injection doses varied and tended to be higher in the aggressive ROP group. Infants with aggressive ROP were 2.08 times more likely to require additional treatment than those with type 1 ROP. When ROP reactivation occurred, laser therapy was preferred as an additional treatment. Conclusion In Korea, the preference for anti-VEGF therapy or laser therapy differed according to ROP subtype, zone and primary or secondary treatment. These findings suggest that ROP treatment are considered according to ROP subtype, location and reactivation. Jang, Ji Hye; Kang, Yong Koo; Park, Han Sang; Kim, Kiyoung; Kim, Sung Soo; Han, Jae Yong; Kim, Hyun Wong; Bang, Jong Wook; Song, Jae Shin; Park, Sang Jun; Woo, Se Joon; Joo, Kwang Sic; Yoo, Woong-Sun; Chung, Inyoung; Cho, Yong-Wun; Lee, Jong Hyun; Choi, Hun Jin; Chung, Yoo-Ri Keimyung Univ, Dongsan Med Ctr, Dept Ophthalmol, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Ophthalmol, Sch Med, Daegu, South Korea; Kyung Hee Univ, Dept Ophthalmol, Sch Med, Seoul, South Korea; Yonsei Univ, Severance Hosp, Inst Vis Res, Dept Ophthalmol,Coll Med, Seoul, South Korea; Inje Univ, Haeundae Paik Hosp, Dept Ophthalmol, Coll Med, Busan, South Korea; Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Ophthalmol, Seoul, South Korea; Gyeongsang Natl Univ, Sch Med, Dept Ophthalmol, Jinju, South Korea; Inje Univ, Ilsan Paik Hosp, Dept Ophthalmol, Coll Med, Busan, South Korea; Ajou Univ, Dept Ophthalmol, Sch Med, Suwon, South Korea ; KANG, YONG KOO/IVH-8723-2023; Yoo, Woong-Sun/O-2777-2019; Woo, Se Joon/I-7357-2013; LEE, JUNGUN/GLR-9927-2022; Park, Sang Jun/C-3234-2015; Woo, Joon/I-7357-2013; Kim, Sung-Soo/ABD-3771-2021; KIM, KIYOUNG/GWM-6103-2022 57218653758; 57204703736; 57208186456; 57190837975; 57837548700; 55728837600; 58083837400; 57212483012; 57891666300; 56144621600; 7402852174; 55648181100; 56187651200; 8561133700; 56024820700; 55690073100; 57015860900; 24340889000 mjmom99@naver.com; BMJ OPEN OPHTHALMOLOGY BMJ OPEN OPHTHALMOL 2397-3269 8 1 ESCI OPHTHALMOLOGY 2023 2 40.5 0.65 2025-06-25 2 2 Retina; Treatment Lasers; Treatment Medical ENDOTHELIAL GROWTH-FACTOR; INTRAVITREAL BEVACIZUMAB; LASER PHOTOCOAGULATION; POSTERIOR RETINOPATHY; RANIBIZUMAB; MANAGEMENT; EFFICACY; PHARMACOKINETICS; REACTIVATION; AFLIBERCEPT Retina; Treatment Lasers; Treatment Medical Angiogenesis Inhibitors; Endothelial Growth Factors; Humans; Infant; Infant, Newborn; Infant, Premature; Intravitreal Injections; Retinopathy of Prematurity; Retrospective Studies; Vascular Endothelial Growth Factor A; bevacizumab; ranibizumab; angiogenesis inhibitor; endothelial cell growth factor; vasculotropin A; aggressive retinopathy of prematurity; Article; female; human; infant; laser therapy; major clinical study; male; prematurity; retina detachment; retrolental fibroplasia; retrospective study; South Korea; treatment response; type 1 retinopathy of prematurity; clinical trial; intravitreal drug administration; multicenter study; newborn; retrolental fibroplasia English 2023 2023-01 10.1136/bmjophth-2022-001166 바로가기 바로가기 바로가기 바로가기
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KeywordsPlus (SCOPUS) SCOPUS에서 자동으로 추출하거나 추가한 색인 키워드입니다.
Language 논문이 작성된 언어입니다. 대부분 English이며, 그 외 다양한 언어로 작성된 논문이 포함될 수 있습니다.
Publication Year 논문이 출판된 연도입니다.
Publication Date 논문의 정확한 출판 날짜입니다 (년-월-일 형식).
DOI Digital Object Identifier. 디지털 객체 식별자로, 논문을 고유하게 식별하는 영구적인 식별번호입니다. 이를 통해 논문의 온라인 위치를 찾을 수 있습니다.