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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Review | Practices of Motivators in Adopting Agile Software Development at Large Scale Development Team from Management Perspective | Agile software development methodologies have become the most popular software development methods in the last few years. These methodologies facilitate rapid development. The low cost and prioritized user satisfaction make these methodologies more attractive. These methodologies were also intended for small scale developmental teams. Therefore, challenges were encountered when these methodologies were used in large-scale development teams. This study was based on the identification of factors which were discovered in our previous study. Some of the factors included "leadership strong commitment and team autonomy ", "cooperative organizational culture ", and "team competency-agile development expertise ". A total of 147 practices were identified in this study via a systematic literature review. These practices will help practitioners and project managers to adopt agile software methodologies and encourage them to the enhance them. | Khan, Rashid Ali; Abrar, Muhammad Faisal; Baseer, Samad; Majeed, Muhammad Faran; Usman, Muhammad; Ur Rahman, Shams; Cho, You-Ze | Qurtuba Univ, Dept Comp Sci, Peshawar 25000, Pakistan; Univ Engn & Technol, Dept Comp Sci, Mardan 23200, Pakistan; Univ Engn & Technol, Dept Comp Syst Engn, Peshawar 25000, Pakistan; Shaheed Benazir Bhutto Univ, Dept Comp Sci, Sheringal 18000, Pakistan; Univ Engn & Technol, Dept Comp Software Engn, Mardan 23200, Pakistan; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | Abrar, Muhammad Faisal/AEE-6150-2022; Muhammad, Usman/W-6993-2019; Usman, Muhammad/P-5066-2015 | 57195471399; 57204396178; 37012568400; 57190983686; 56844860100; 57270540500; 7404469829 | rashid.buniry@gmail.com;abrarfaisal49@gmail.com;drsamadbaseer@uetpeshawar.edu.pk;m.faran.majeed@ieee.org;usman@uetmardan.edu.pk;shams@uetmardan.edu.pk;yzcho@ee.knu.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 19 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.36 | 2025-07-30 | 6 | 15 | practices; systematic literature review; agile transformation; scaling agile | CRITICAL SUCCESS FACTORS; DEVELOPMENT METHODOLOGIES; CHALLENGES; PEOPLE | Agile transformation; Practices; Scaling agile; Systematic literature review | English | 2021 | 2021-10 | 10.3390/electronics10192341 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Proxy-Based Adaptive Transmission of MP-QUIC in Internet-of-Things Environment | With the growth of Internet of Things (IoT) services and applications, the efficient transmission of IoT data has been crucially required. The IETF has recently developed the QUIC protocol for UDP-based multiplexed and secure transport. The Multipath QUIC (MP-QUIC) is also being discussed as an extension of QUIC in the multipath network environment. In this paper, we propose a proxy-based adaptive MP-QUIC transmission for throughput enhancement in the IoT environment. In the proposed scheme, a proxy device is employed between IoT clients and IoT server to aggregate the traffics of many clients in the access network. The proxy will transport a large among of traffics to the server, adaptively to the network conditions, by using multiple paths in the backbone network. For this purpose, the proxy device employs a path manager to monitor the current network conditions and a connection manager to manage the MP-QUIC connections with the IoT server over the backbone network with multiple paths. For effective MP-QUIC transmission, the proxy will transmit the prioritized packets to the server using the best path with the lowest round-trip time (RTT), whereas the non-prioritized packets are delivered over the other paths for traffic load balancing in the network. From the testbed experimentations with the MP-QUIC implementation and ns-3 simulation modules, we see that the proposed scheme can outperform the normal QUIC (using a single path) and the existing MP-QUIC scheme (using the round-robin policy) in terms of response delay and total transmission delay. Such performance gaps tend to increase as the link delays and packet loss rates get larger in the network. | Firmansyah, Muhammad Hafidh; Jung, Joong-Hwa; Koh, Seok-Joo | Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu 41566, South Korea | ; Firmansyah, Muhammad Hafidh/KVX-8263-2024 | 57219819685; 57194055389; 8958394800 | hafid@knu.ac.kr;godopu16@gmail.com;sjkoh@knu.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 17 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.26 | 2025-07-30 | 3 | 4 | QUIC; MP-QUIC; IoT; proxy; path manager; connection manager | Connection manager; IoT; MP-QUIC; Path manager; Proxy; QUIC | English | 2021 | 2021-09 | 10.3390/electronics10172175 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Reducing Complexity of Server Configuration through Public Cloud Storage | Hosting networking applications typically involves a server publicly accessible over the Internet. However, preparing a server requires excessive time and effort, particularly for non-expert users. This is because users configure multiple elements including the server, host firewalls, and network firewalls, while considering their interactions. To address this problem, we propose a method that uses public cloud storage, such that all messages are communicated through the storage between the server and clients. As the storage is public and accessible over the Internet, users need not consider firewalls and can focus on configuring the server. We implemented the proposed method for web applications and evaluated its performance by accessing applications from 90 hosts in diverse locations. The evaluation showed that the proposed method does not incur extra delays and clients can access the applications as reliably as the current practice of configuring servers. We also recruited 54 participants and examined the time required to configure a server with the proposed method compared to configuration using current practice. This study demonstrated that the proposed method reduces configuration time from 40-60 to nearly 30 min. We believe that the proposed method provides a basis for improving the manageability of server configuration. | Lee, Sihyung | Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu 41566, South Korea | 15623380100 | sihyunglee@knu.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 11 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.13 | 2025-07-30 | 1 | 2 | server configuration; network configuration; public cloud storage; networking applications | Network configuration; Networking applications; Public cloud storage; Server configuration | English | 2021 | 2021-06 | 10.3390/electronics10111277 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Sensorless PMSM Drive Inductance Estimation Based on a Data-Driven Approach | In the permanent magnet synchronous motor (PMSM) sensorless drive method, motor inductance is a decisive parameter for rotor position estimation. Due to core magnetic saturation, the motor current easily invokes inductance variation and degrades rotor position estimation accuracy. For a constant load torque, saturated inductance and inductance error in the sensorless drive method are constant. Inductance error results in constant rotor position estimation error and minor degradations, such as less optimal torque current, but no speed estimation error. For a periodic load torque, the inductance parameter error periodically fluctuates and, as a result, the position estimation error and speed error also periodically fluctuate. Periodic speed error makes speed regulation and load torque compensation especially difficult. This paper presents an inductance parameter estimator based on polynomial neural network (PNN) machine learning for PMSM sensorless drive with a period load torque compensator. By applying an inductance estimator, we also proposed a magnetic saturation compensation method to minimize periodic speed fluctuation. Simulation and experiments were conducted to validate the proposed method by confirming improved position and speed estimation accuracy and reduced system vibration against periodic load torque. | Park, Gwangmin; Kim, Gyeongil; Gu, Bon-Gwan | Kyungpook Natl Univ, Sch Energy Engn, Daegu 41566, South Korea | 35305888000; 57222521137; 50061273700 | gmpark00@knu.ac.kr;ruddlf0222@naver.com;bggu@knu.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 7 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.97 | 2025-07-30 | 11 | 15 | sensorless control; magnetic saturation; inductance variation; polynomial neural network (PNN); group method of data handling (GMDH); noise; vibration; harshness (NVH) | Group method of data handling (GMDH); Inductance variation; Magnetic saturation; Noise, vibration, and harshness (NVH); Polynomial neural network (PNN); Sensorless control | English | 2021 | 2021-04 | 10.3390/electronics10070791 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Textile Triboelectric Nanogenerators with Diverse 3D-Spacer Fabrics for Improved Output Voltage | Electrically superior triboelectric nanogenerators (TENG) using 3D fabric and PDMS show great application potential for biokinetic energy harvesting and multifunctional self-power devices. In this study, TENG with fabric-PDMS-fabric structure was produced using various 3D fabrics and PDMS. The peak-to-peak output voltage of various 3D fabrics was compared. The output voltage changes due to structure and vertical fibers. Also, the coefficient of surface friction between the PDMS and the fabric improves the output voltage. TENG using different 3D-spacer polymeric fabrics showed different maximum peak-to-peak output voltage performance. It is attributed to the stiffness, lateral elasticity and 3D morphology of the fabrics. It is considered that those factors including stiffness, lateral elasticity and 3D morphology influence the densities in vertical and lateral fiber to fiber interaction. | Kwon, Dae-Hyeon; Kwon, Jin-Hyuk; Jeong, Jaebum; Lee, Youngju; Biswas, Swarup; Lee, Dong-Wook; Lee, Sohee; Bae, Jin-Hyuk; Kim, Hyeok | Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehakro, Daegu 41566, South Korea; Korea Inst Ceram Engn & Technol KICET, Nano Mat & Nano Technol Ctr, Jinju 52851, South Korea; Korea Inst Ind Technol KITECH, Appl Robot R&D Dept, Ansan 15588, South Korea; Univ Seoul, Inst Informat Technol, Sch Elect & Comp Engn, 163 Seoulsiripdaero, Seoul 02504, South Korea; Gyeongsang Natl Univ, Res Inst Nat Sci, Dept Clothing & Text, 501 Jinjudaero, Gyeongsangnamdo 52828, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | Biswas, Swarup/AAH-5067-2019 | 57222761479; 7202469243; 57208145522; 57222758878; 7402251506; 55516365700; 37056928800; 35326180700; 57191718658 | kdh0663@naver.com;rnjs3055@naver.com;iriver0208@naver.com;dydwn0603@naver.com;Biswas.swarup1988@gmail.com;dwlee@kitech.re.kr;sohee.lee@gnu.ac.kr;jhbae@ee.knu.ac.kr;hyeok.kim@uos.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 8 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.65 | 2025-07-30 | 10 | 11 | 3D fabric; triboelectric nanogenerator; knitting structure; output voltage | 3D fabric; Knitting structure; Output voltage; Triboelectric nanogenerator | English | 2021 | 2021-04 | 10.3390/electronics10080937 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Virtualization of Self-Driving Algorithms by Interoperating Embedded Controllers on a Game Engine for a Digital Twining Autonomous Vehicle | Computer simulation based on digital twin is an essential process when designing self-driving cars. However, designing a simulation program that is exactly equivalent to real phenomena can be arduous and cost-ineffective because too many things must be implemented. In this paper, we propose the method using the online game GTA5 (Grand Theft Auto5), as a groundwork for autonomous vehicle simulation. As GTA5 has a variety of well-implemented objects, people, and roads, it can be considered a suitable tool for simulation. By using OpenCV (Open source computer vision) to capture the GTA5 game screen and analyzing images with YOLO (You Only Look Once) and TensorFlow based on Python, we can build a quite accurate object recognition system. This can lead to writing of algorithms for object avoidance and lane recognition. Once these algorithms have been completed, vehicles in GTA5 can be controlled through codes composed of the basic functions of autonomous driving, such as collision avoidance and lane-departure prevention. In addition, the algorithm tested with GTA5 has been implemented with a programmable RC car (Radio control car), DonkeyCar, to increase reliability. By testing those algorithms, we can ensure that the algorithms can be conducted in real time and they cost low power and low memory size. Therefore, we have found a way to approach digital twin technology one step more easily. | Yun, Heuijee; Park, Daejin | Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea | ; Yun, Heuijee (Heejee)/GOJ-9000-2022 | 57222516795; 55463943600 | heuijee@knu.ac.kr;boltanut@knu.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 17 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.91 | 2025-07-30 | 8 | 14 | autonomous driving; simulation; digital twin; lane detection; game engine; OpenCV; DonkeyCar | CO-SIMULATION; SYSTEM; DESIGN | Autonomous driving; Digital twin; DonkeyCar; Game engine; Lane detection; OpenCV; Simulation | English | 2021 | 2021-09 | 10.3390/electronics10172102 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Security Awareness: The First Step in Information Security Compliance Behavior | In this study, we use the attentional phase of social learning theory to link workplace security-related experiences and observations to employees' security awareness. The responses of 398 organizational employees serve to test our research model using structural equational modeling with AMOS 22.0. The results show security awareness arises from both explicit and subjective security experiences in the workplace. Our respondents indicate knowledge of a physical system has little, if any, effect on security awareness. However, security education, policy, visibility and managerial security participation are important for producing security awareness. Furthermore, managerial participation strengthens the links between organizational security efforts and security awareness. We discuss the implications of our study for future security compliance research and practice. | Hwang, Inho; Wakefield, Robin; Kim, Sanghyun; Kim, Taeha | Korea Polytech Univ, Shihung, South Korea; Baylor Univ, Waco, TX 76798 USA; Kyungpook Natl Univ, Daegu, South Korea; Chung Ang Univ, Seoul, South Korea | 55167929000; 8648274400; 57210208391; 59782842700 | ksh@knu.ac.kr; | JOURNAL OF COMPUTER INFORMATION SYSTEMS | J COMPUT INFORM SYST | 0887-4417 | 2380-2057 | 61 | 4 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS | 2021 | 3.317 | 50.3 | 3.79 | 2025-07-30 | 44 | 54 | Word; information security; awareness; social learning theory; compliance intention; security visibility; management participation; security policy | POLICY COMPLIANCE; SYSTEMS; MANAGEMENT; MOTIVATION; IMPACT; MODEL; PRESSURES; KNOWLEDGE; THREATS | awareness; compliance intention; information security; management participation; security policy; security visibility; social learning theory; Word | Managers; Security systems; Visibility; awareness; compliance intention; Security policy; Social learning theory; Word; Security of data | English | 2021 | 2021-07-04 | 10.1080/08874417.2019.1650676 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Antiplatelet effect of cudraxanthone B is related to inhibition of calcium mobilization, αIIbβ3 activation, and clot retraction | Cudrania tricuspidata (C. tricuspidata) is widespread throughout Asia and has known to have various physiological activities such as, inflammation, diabetes, obesity and tumor. Cudrania tricuspidata, a rich source of xanthones and flavonoids, have been investigated phytochemically and biologically. However, research of these compounds on platelets is limited. Therefore, we searched for a new substance from various xanthones and flavonoids in C. tricuspidata. We confirmed the results that steppogenin and isoderrone suppress human platelets among the various components isolated from C. tricuspidata, and as a result of analyzing the antiplatelet effect using additional new samples, we found that cudraxanthone B (CXB) has the effect of suppressing human platelets. Therefore, we studied the potential efficacies of CXB on human platelet aggregation and its inhibitory mechanism. Inhibitory effects of CXB on platelet aggregation were assessed using washed platelets, followed by measurement of [Ca2+](i) mobilization and dense granule release, fibrinogen binding, fibronectin adhesion assay, and clot retraction. Our data showed that CXB suppressed collagen-induced human platelet aggregation, [Ca2+](i) mobilization, fibrinogen binding, fibronectin adhesion and clot retraction without cytotoxicity. Thus, our results show that inhibitory effects of CXB on human platelet activation and thrombus formation, suggesting its potential use as a natural substance for preventing platelet-induced thrombosis. | Shin, Jung-Hae; Irfan, Muhammad; Rhee, Man Hee; Kwon, Hyuk-Woo | Catholic Kwandong Univ, Dept Biomed Lab Sci, Kangnung 25601, South Korea; Kyungpook Natl Univ, Coll Vet Med, Lab Physiol & Cell Signaling, Daegu 41566, South Korea; Univ Illinois, Dept Oral Biol, Chicago, IL USA; Far East Univ, Dept Biomed Lab Sci, Eumseong 27601, Chungbuk, South Korea | Rhee, Man/O-5705-2016; Irfan, Muhammad/AAY-1961-2021 | 56244056800; 35069404400; 57211035357; 55200547400 | kwonhw@kdu.ac.kr; | APPLIED BIOLOGICAL CHEMISTRY | APPL BIOL CHEM | 2468-0834 | 2468-0842 | 64 | 1 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2021 | 3.206 | 50.4 | 0.26 | 2025-07-30 | 7 | 6 | Cudraxanthone B; Ca2+ mobilization; alpha IIb/beta 3 activation; Granule secretion; Clot retraction | Ca<sup>2+</sup> mobilization; Clot retraction; Cudraxanthone B; Granule secretion; αIIb/β3 activation | Adhesion; Calcium; Chemical activation; Flavonoids; Granulation; Ca 2+; Ca2+ mobilization; Clot retraction; Cudraxanthone B; Flavonoid; Granule secretion; Inhibitory effect; Mobilisation; Platelet aggregation; Αiib/β3 activation; Platelets | English | 2021 | 2021-01 | 10.1186/s13765-020-00575-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Enhanced ceramides production by Lactobacillus rhamnosus IDCC 3201 and its proposed mechanism | The use of probiotics has been applied for a variety of fields (e.g., immune system, mental health, and heart). In this study, the feasibility of lysates from L. rhamnosus IDCC 3201 for cosmetic ingredients was evaluated. More specifically, enhanced ceramides production in human epidermal keratinocytes by the lysates and its proposed machanism were investigated through in vitro and genome analysis. In results, enhanced spingomyelinase activity and thereby increased ceramides production by the lysates from L. rhamnosus IDCC 3201 was observed. Furthermore, it was found that the existence of glucosylceramdase in L. rhamonsus IDCC 3201 was attributed to enhanced ceramides production. Finally, it was verified that the lysates from L. rhamonsus IDCC 3201 was regarded as safe for its use as cosmetic materials. Thus, these findings have significant implications that might lead to the development of functional and safe cosmetic products from probiotics. | Kim, Myun Soo; Lee, Minjee; Oh, Hanna; Seo, Wonsang; Kim, Gwang-Seob; Ban, O-Hyun; Shin, Minhye; Jung, Young Hoon; Yang, Jungwoo | INTERCARE, 1 Naeyuri 1 Gil, Cheonan Si 31027, Chungcheongnam, South Korea; Ildong Biosci, 17 Poseunggongdan Ro, Pyeongtaek Si 17957, Gyeonggi Do, South Korea; Ildong Pharmaceut, 2 Baumoe Ro 27 Gil, Seoul 06752, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Seoul Natl Univ, Res Inst Agr & Life Sci, Seoul 00826, South Korea; Seoul Natl Univ, Dept Agr Biotechnol, Seoul 00826, South Korea; Kyungpook Natl Univ, Inst Fermentat Biotechnol, Daegu 41566, South Korea | ; Jung, Young/F-1703-2013 | 57225050979; 57221979843; 57225044456; 57439134500; 57225053759; 57219226382; 57208401604; 55550063700; 56076383700 | younghoonjung@knu.ac.kr;yjw@ildong.com; | APPLIED BIOLOGICAL CHEMISTRY | APPL BIOL CHEM | 2468-0834 | 2468-0842 | 64 | 1 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2021 | 3.206 | 50.4 | 0.2 | 2025-07-30 | 5 | 4 | Ceramides; Glucosylceramidase; Probiotics; Skin health; Sphingomyelinase | STRATUM-CORNEUM; ANTIBIOTIC-RESISTANCE; SPHINGOMYELINASE; BARRIER | Ceramides; Glucosylceramidase; Probiotics; Skin health; Sphingomyelinase | Ceramides; Cosmetics; Cosmetics ingredient; Glucosylceramidase; Human epidermal keratinocytes; In-vitro analysis; Lactobacillus rhamnosus; Lysates; Mental health; Probiotics; Skin health; Sphingomyelinase; Probiotics | English | 2021 | 2021-12 | 10.1186/s13765-021-00620-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Potato extract inhibits lipase activity and ameliorates gut microbiome dysbiosis and weight gain in mice fed a high-fat diet | Curtailing the absorption of triglycerides (TGs) is a preferred pathway for treating obesity. Our previous study demonstrated that the water-soluble fraction from potato could inhibit the lipase activity of patatin, one of the major proteins in potato. This aqueous fraction was purified and concentrated by deproteination and reversed-phase chromatography to investigate the effectiveness against obesity. Biochemical analyses indicated that the fraction non-competitively inhibited pancreatic lipase (PLase) with a half-maximal inhibitory concentration of 10.17 mu g/mL, and was named as potato-derived lipase inhibitory fraction (PI). Animal studies on C57BL/6 mice showed that in mice fed a high-fat diet (HFD), PI treatment resulted in reductions in body weight gain, adipose fat deposition, and liver TGs, and ameliorated the gut microbiome dysbiosis caused by HFD feeding; meanwhile, orlistat, a well-known lipase inhibitor, diverged the gut microbiome profile in mice fed a HFD. High resolution electronspray ionization-Orbitrap tandem mass spectrometry identified gallic acid, 4-hydroxybenzoic acid, and protocatechuic acid, which are known to have lipase inhibitory activities, in PI. However, these compounds could not reconstitute comparable specific inhibitory activity of PI inferring the existence of another inhibitory compound(s) to be identified in PI. | Katimbwa, Dorsilla Anono; Ma, Jinsung; Kim, Chang-Kil; Hahn, Dongyup; Lim, Jinkyu | Kyungpook Natl Univ, Dept Food Biomat, 80 Daehak Ro, Daegu, South Korea; Kyungpook Natl Univ, Dept Hort Sci, Daegu, South Korea | 57221787136; 57200022185; 7409880701; 36554163400; 7403454071 | jkylim@knu.ac.kr; | APPLIED BIOLOGICAL CHEMISTRY | APPL BIOL CHEM | 2468-0834 | 2468-0842 | 64 | 1 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2021 | 3.206 | 50.4 | 0.46 | 2025-07-30 | 8 | 8 | Gut microbiome; Obesity; Pancreatic lipase inhibition; Potatoes (Solanum tuberosum L; tubers) | Gut microbiome; Obesity; Pancreatic lipase inhibition; Potatoes (Solanum tuberosum L. tubers) | Chromatography; Mass spectrometry; Nutrition; Gut microbiome; High-fat-diet; Lipase activity; Lipase inhibitions; Microbiome; Obesity; Pancreatic lipase; Pancreatic lipase inhibition; Potato (solanum tuberosa L tuber); Solanum tuberosum L; Mammals | English | 2021 | 2021-01-28 | 10.1186/s13765-021-00590-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Responses of inflammation signaling pathway by saucerneol D from elicitor-treated Saururus chinensis on pro-inflammatory responses in LPS-stimulated Raw 264.7 cell | This study confirmed the association with inflammation-related proteins, mediators, and cytokines using saucerneol D from Saururus chinensis leaf, a useful ingredient increased through elicitor treatment. To confirm the anti-inflammatory effect, saucerneol D were treated with lipopolysaccharide, which induces pro-inflammatory factors in Raw 264.7 cell. The pro-inflammatory influences were measured by dint of chemical assay and western blotting as well as ELISA. As a result, the content of saucerneol D was changed when eicitor was treated by various concentration (1.5, and 3 mg/mL) in S. chinensis leaves. In addition, the expression levels of hyaluronidase and pro-inflammatory-related factors [nitric oxide (NO), inducible NO synthase (iNOS), and cyclooxygenase-2 (COX-2)] were regulated according to the saucerneol D content in the elicitor-treated and non-treated groups. Therefore, after confirming that saucerneol D has an inhibitory effect on pro-inflammatory-related factors, saucerneol D was adjusted by concentration and compared with the control substance to verify the efficacy. Saucerneol D was adjusted to a concentration that did not toxic to macrophages through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Saucerneol D controlled at various concentrations inhibited iNOS and COX-2 proteins. NO produced by iNOS activity, prostaglandin E-2 (PGE(2)), an inflammatory mediator produced by COX-2 activity, and pro-inflammatory cytokines [interleukin-1 beta (IL-1 beta), IL-6, tumor necrosis factor-alpha (TNF-alpha)] were significantly suppressed. Therefore, it was confirmed that saucerneol D, an active ingredient increased by the elicitor treatment, could be used as a functional material that controls inflammatory factors. | Lee, Eun-Ho; Cho, Young-Je | Kyungpook Natl Univ, Food & Bioind Res Inst, Sch Food Sci & Biotechnol, 80 Univ St, Daegu 41566, South Korea | 56347429100; 55265396300 | yjcho@knu.ac.kr; | APPLIED BIOLOGICAL CHEMISTRY | APPL BIOL CHEM | 2468-0834 | 2468-0842 | 64 | 1 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2021 | 3.206 | 50.4 | 0.2 | 2025-07-30 | 2 | 3 | Cytokine; Elicitation; Inflammation; Macrophages; Saucerneol D | Cytokine; Elicitation; Inflammation; Macrophages; Saucerneol D | Cell death; Functional materials; Macrophages; Pathology; Proteins; Cyclooxygenase 2; Cytokines; Elicitation; Inflammation; Inflammatory response; Raw 264.7 cells; Related factors; Saucerneol D; Signalling pathways; Synthases; Nitric oxide | English | 2021 | 2021-02-13 | 10.1186/s13765-020-00585-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Simultaneous determination of 13 mycotoxins in feedstuffs using QuEChERS extraction | Mycotoxins are secondary metabolites produced by various fungi and are known to have a significant negative impact on human and animal health. When feedstuffs are contaminated with mycotoxins, their toxicities may be caused a variety of diseases. In this study, the residual mycotoxins in feedstuffs were analyzed using LC-MS/MS incorporated with QuEChERS extraction. Analytical method validation was performed for LOD, LOQ, linearity, and recoveries with consideration of matrix effects prior to the residual analysis. They were all reached to the accepted range of validation level. Using 39 feedstuff samples (5 g) for mycotoxin analysis, nine samples were contaminated by four major mycotoxins such as fumonisin B1 (FB1), deoxynivalenol, fumonisin B2, and zearalenone. Among them, FB1 was detected at the highest concentration as 18.0943 mg/kg. The total sum of fumonisins in 39 samples did not exceed the maximum residual level (MRL) criterion set by Korean Food and Drug Administration. Altogether, intensive management of mycotoxins in Korean feedstuffs should be implemented with proper and routine monitoring, even their residual concentrations are not exceeded over the MRL levels because of high frequent detection found in this study. | Jo, Hyeong-Wook; Park, Min-Kyu; Heo, Hyo-min; Jeon, Hwang-Ju; Choi, Sung-Deuk; Lee, Sung-Eun; Moon, Joon-Kwan | Hankyong Natl Univ, Hansalim Agrofood Anal Ctr, Ind Acad Cooperat Fdn, Suwon 16500, South Korea; Ulsan Natl Inst Sci & Technol UNIST, Sch Urban & Environm Engn, Ulsan 44919, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Hankyong Natl Univ, Dept Plant Life & Environm Sci, Anseong 17579, South Korea | Jeon, Hwangju/JDW-9035-2023; Choi, Sung-Deuk/F-4827-2010 | 56763478100; 57037486700; 57222635211; 56328792200; 58530775200; 55890041600; 8536720000 | sdchoi@unist.ac.kr;selpest@knu.ac.kr;jkmoon264@gmail.com; | APPLIED BIOLOGICAL CHEMISTRY | APPL BIOL CHEM | 2468-0834 | 2468-0842 | 64 | 1 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2021 | 3.206 | 50.4 | 0.98 | 2025-07-30 | 17 | 17 | Mycotoxins; QuEChERS; LC-MS/MS; Feedstuffs; Fumonisines | ASPERGILLUS-FLAVUS; FOOD; CONTAMINATION; ANTIFUNGAL; FUNGI | Feedstuffs; Fumonisines; LC–MS/MS; Mycotoxins; QuEChERS | Extraction; Metabolites; Feedstuffs; Fumonisin; Fumonisin B1; Fumonisine; LC-MS-MS; Lc.ms/ms; QuEChERS; Residual levels; Secondary metabolites; Simultaneous determinations; Mycotoxins | English | 2021 | 2021-04-05 | 10.1186/s13765-021-00602-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Synthesis, characterization, and antioxidant activity in vitro of selenium-Euryale ferox Salisb. polysaccharide | In order to obtain and explore selenide composed of selenium and polysaccharide, three parameters were selected to optimize the synthesis process of selenium-Euryale ferox Salisb. polysaccharide (Se-ESPS) by Box-Behnken design. Furthermore, ESPS-B1 separated from ESPS was selenitized to Se-ESPS-B1 by the optimal synthesis process, then the characterization, and antioxidant activity in vitro of Se-ESPS-B1 were explored. The result manifested that the Se content of Se-ESPS was (2.915 +/- 0.03) mg/g according to the optimal synthesis process of Se-ESPS (reaction time at 5 h, reaction temperature at 81 celcius, weight ratio of Na2SeO3 to ESPS at 0.9 g/g). A series of detection results indicated that the characterizations of Se-ESPS-B1 were apparently distinguished from that of ESPS-B1. Moreover, the antioxidant experiments in vitro demonstrated that Se-ESPS-B1 could exert antioxidant activity by scavenging DPPH, ABTS,center dot OH, and increasing reduction ability. In conclusion, the synthesis process is an effective approach to harvest selenium-polysaccharide, and Se-ESPS-B1 may be utilized as a potential antioxidant or selenium nutritional supplement. | Dong, Fang; Zheng, Hu-Zhe; Jeong, Woo-Sik; Chung, Shin-Kyo; Qu, Zhong-Yuan; Zou, Xiang; Liu, Chen; Xiang, Qiong; Feng, Feng | Jiangsu Food & Pharmaceut Sci Coll, Sch Hlth Sci, Huaian 223003, Peoples R China; Harbin Univ Commerce, Sch Pharm, Harbin 150076, Peoples R China; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Univ Sussex, Sch Life Sci, Brighton BN1 9RH, E Sussex, England; China Pharmaceut Univ, Sch Life Sci & Technol, Nanjing 211198, Peoples R China | Jeong, Woo-Sik/AAN-6885-2020 | 36960153500; 35217210000; 10440750200; 7404292790; 21234187700; 8678784200; 57226711750; 57226722179; 59801104800 | dong1234fang@126.com;20171018@jsfpc.edu.cn; | APPLIED BIOLOGICAL CHEMISTRY | APPL BIOL CHEM | 2468-0834 | 2468-0842 | 64 | 1 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2021 | 3.206 | 50.4 | 0.91 | 2025-07-30 | 14 | 17 | Selenium-Euryale ferox Salisb; polysaccharide; Synthesis optimization; Characterization; Antioxidant activity | EXTRACTION OPTIMIZATION; SELENYLATION MODIFICATION; ANTITUMOR-ACTIVITY; POMACE EXTRACTS; SELENOPROTEINS | Antioxidant activity; Characterization; Selenium-Euryale ferox Salisb. polysaccharide; Synthesis optimization | Antioxidants; Selenium compounds; Sodium compounds; Antioxidant activities; Characterization; In-vitro; Optimal synthesis; Selenia-euryale ferox salisb.; Selenides; Selenium and; Synthesis optimization; Synthesis process; Three parameters; Selenium | English | 2021 | 2021-12 | 10.1186/s13765-021-00631-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Reconfiguration of homomorphisms to reflexive digraph cycles | Let G be a digraph and B be a fixed reflexive digraph cycle. Given two homomorphisms phi, phi' : G -> B, a walk from phi of phi' in the Hom-graph Hom(G, B) corresponds to what is often called a reconfiguration sequence of the homomorphisms. Except in the case that B contains a 4-cycle, containing an oriented cycle of algebraic girth 0, we give a polynomial time algorithm that either finds a path between two given homomorphisms or discovers an obstruction certifying the non-existence of such a path. (C) 2021 Elsevier B.V. All rights reserved. | Brewster, Richard C.; Lee, Jae-baek; Siggers, Mark | Thompson Rivers Univ, Dept Math, Kamloops, BC, Canada; Univ Victoria, Dept Math & Stat, Victoria, BC, Canada; Kyungpook Natl Univ, Coll Nat Sci, Daegu 702701, South Korea | ; Lee, Juhyung/JQV-8143-2023 | 7005644208; 57201389745; 14519683600 | rbrewster@tru.ca;dlwoqor0923@uvic.ca;mhsiggers@knu.ac.kr; | DISCRETE MATHEMATICS | DISCRETE MATH | 0012-365X | 1872-681X | 344 | 8 | SCIE | MATHEMATICS | 2021 | 0.961 | 50.6 | 0.4 | 2025-07-30 | 2 | 3 | Graph homomorphism; Recolouring; Reconfiguration; Reflexive digraph; Hom-graph | Graph homomorphism; Hom-graph; Recolouring; Reconfiguration; Reflexive digraph | English | 2021 | 2021-08 | 10.1016/j.disc.2021.112441 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Pharmacokinetics of α-amanitin in mice using liquid chromatography-high resolution mass spectrometry and in vitro drug-drug interaction potentials | The aim of this study was to determine pharmacokinetics of alpha-amanitin, a toxic bicyclic octapeptide isolated from the poisonous mushrooms, following intravenous (iv) or oral (po) administration in mice using a newly developed and validated liquid chromatography-high resolution mass spectrometry. The iv injected alpha-amanitin disappeared rapidly from the plasma with high a clearance rate (26.9-30.4 ml/min/kg) at 0.1, 0.2, or 0.4 mg/kg doses, which was consistent with a rapid and a major excretion of alpha-amanitin via the renal route (32.6%). After the po administration of alpha-amanitin at doses of 2, 5, or 10 mg/kg to mice, the absolute bioavailability of alpha-amanitin was 3.5-4.8%. Due to this low bioavailability, 72.5% of the po administered alpha-amanitin was recovered from the feces. When alpha-amanitin is administered po, the tissue to plasma area under the curve ratio was higher in stomach > large intestine > small intestine > lung similar to kidneys > liver but not detected in brain, heart, and spleen. The high distribution of alpha-amanitin to intestine, kidneys, and liver is in agreement with the previously reported major intoxicated organs following acute alpha-amanitin exposure. In addition, alpha-amanitin weakly or negligibly inhibited cytochrome P450 and 5'-diphospho-glucuronosyltransferase enzymes activity in human liver microsomes as well as major drug transport functions in mammalian cells overexpressing transporters. Data suggested remote drug interaction potential may be associated with alpha-amanitin exposure. | Park, Ria; Choi, Won-Gu; Lee, Min Seo; Cho, Yong-Yeon; Lee, Joo Young; Kang, Han Chang; Sohn, Chang Hwan; Song, Im-Sook; Lee, Hye Suk | Catholic Univ Korea, Coll Pharm, Bucheon 14662, South Korea; Catholic Univ Korea, BK21 Four Sponsored Adv Program SmartPharma Leade, Bucheon, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Emergency Med, Seoul, South Korea; Kyungpook Natl Univ, Daegu, South Korea | ; Kang, Han/I-5999-2019; Cho, Yong-Yeon/AAD-4263-2020 | 57215577826; 57184763300; 57225079010; 55472207900; 57215684977; 36150873700; 35933678400; 7201564500; 35316111800 | sianalee@catholic.ac.kr; | JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES | J TOXICOL ENV HEAL A | 1528-7394 | 1087-2620 | 84 | 20 | SCIE | ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH;TOXICOLOGY | 2021 | 3.24 | 50.7 | 1.12 | 2025-07-30 | 16 | 17 | alpha-amanitin; pharmacokinetics; tissue distribution; drug interaction; drug metabolizing enzymes; drug transporters | BETA-AMANITIN; AMATOXINS; QUANTIFICATION; VALIDATION; PHALLOIDIN; MUSHROOMS; TOXICITY; PLASMA; TOXINS; DAMAGE | drug interaction; drug metabolizing enzymes; drug transporters; pharmacokinetics; tissue distribution; α-amanitin | Alpha-Amanitin; Animals; Chromatography, Liquid; Dose-Response Relationship, Drug; Drug Interactions; Humans; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Microsomes; Poisons; ABC transporter subfamily B; alpha amanitin; breast cancer resistance protein; cytochrome P450; cytochrome P450 1A2; cytochrome P450 2A6; cytochrome P450 2B6; cytochrome P450 2C19; cytochrome P450 2C8; cytochrome P450 2C9; cytochrome P450 2D6; cytochrome P450 3A4; drug metabolizing enzyme; glucuronosyltransferase; mycotoxin; organic anion transporter; organic anion transporter 1; organic anion transporter 3; organic cation transporter; organic cation transporter 2; solute carrier organic anion transporter 1B1; solute carrier organic anion transporter 1B3; unclassified drug; verproside; alpha amanitin; intoxication; animal experiment; area under the curve ratio; Article; controlled study; drug bioavailability; drug clearance; drug distribution; drug excretion; electrospray; elimination half-life; feces; high performance liquid chromatography; human; human cell; human tissue; in vitro study; large intestine; liquid chromatography; liquid chromatography-mass spectrometry; liver; male; mass spectrometry; mouse; nonhuman; pharmacokinetic parameters; small intestine; tissue distribution; animal; dose response; drug interaction; enzymology; Institute for Cancer Research mouse; metabolism; microsome | English | 2021 | 2021-10-18 | 10.1080/15287394.2021.1944942 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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