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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Article | Cardiovascular Responses to Nasal Stimulation Under Ethmoidal-Maxillary Nerve Block and Lidocaine Gel in Anesthetized Beagles | This study aimed to compare the effect of ethmoidal-maxillary nerve block (EMBLOCK) and topical application of 2% lido-caine gel (LGEL) on cardiovascular variables (heart rate and arterial blood pressure) during mechanical stimulation of the nasal cavity. The working hypothesis was that both techniques (EMBLOCK and LGEL) similarly blunt the cardiovascular responses to the stimulation. Six beagles were anesthetized using alfaxalone and isoflurane on three occasions with each treatment (EMBLOCK, LGEL, and control) in random order. The nasal cavity from the nose tip to the medial canthus was stimulated with a standard-tip cotton swab, and cardiovascular variables were recorded before and after stimulation. The maximum increases in heart rate and blood pressure were significantly smaller in EMBLOCK and LGEL than in the control. There was no significant difference between EMBLOCK and LGEL. Therefore, although further clinical studies are required, EMBLOCK and LGEL can be used because both EMBLOCK and LGEL attenuated the cardiovascular response to mechanical stimulation of the nasal cavity in dogs. | Kim, Hyunseok; Son, Won-gyun; Jang, Min; Kim, Dalhae; Shin, Donghwi; Kim, Jiyoung; Lee, Inhyung | Seoul Natl Univ, Dept Vet Surg Anesthesiol, Seoul, South Korea; Seoul Natl Univ, Coll Vet Med, Dept Vet Clin Sci, Seoul, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Vet Clin Sci, Daegu, South Korea | Lee, Inhyung/AAG-5018-2020; Kim, Hyunseok/NPI-8051-2025 | inhyunglee@snu.ac.kr; | JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION | J AM ANIM HOSP ASSOC | 0587-2871 | 1547-3317 | 58 | 6 | SCIE | VETERINARY SCIENCES | 2022 | 1.3 | 49.7 | 2 | BRONCHOSCOPY; ANESTHESIA; INJECTION | English | 2022 | 2022 (NOV-DEC) | 10.5326/jaaha-ms-7183 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Seasonal changes in the expression of molecular markers of stallion germ cells | The economic impacts of infertility and subfertility of stallions greatly influence the horse breeding in-dustry. Self-renewal and differentiation of spermatogonial stem cells are the initial processes to maintain an adequate sperm population. Thus, understanding these processes may provide useful information to reveal the causes and remedies of subfertile and infertile stallions. Stallions are seasonal breeders. About 50% of the sperm population is reduced during the non-breeding season (NBS) in stallions. The sea-sonal regulation of spermatogenesis renders stallions as ideal models to understand the process of sperm production. Furthermore, comparing internal and external factors related to spermatogenesis during the breeding season (BS) and NBS may provide a solution for subfertile/infertile stallions. It is especially perti-nent to study the expression pattern of different protein markers during undifferentiated, differentiating, and differentiated spermatogonia. Deleted in azoospermia-like (DAZL), undifferentiated cell transcription factor 1 (UTF-1), and protein gene product 9.5 (PGP9.5) are the molecular markers expressed at different stages of spermatogenesis. However, whether the expression pattern of these molecular markers is similar throughout the year in stallion remains undetermined. The objectives of this study were to (1) investigate the expression pattern and localization of DAZL, UTF-1, and PGP9.5 within seminiferous tubules and (2) evaluate the relative mRNA levels of these three germ cell markers in stallion testes during BS and NBS. Immunohistochemistry was performed to check and compare the expression pattern and localization of DAZL, UTF-1, and PGP9.5 antibodies. Reverse transcription-quantitative PCR analysis was performed to calculate the relative mRNA expression levels in the testes. Testicular tissues from thoroughbred stallions were collected during routine castration that was carried out in field conditions. Immunostaining of germ cells with DAZL and UTF-1 in BS and NBS were not significantly different. However, the relative mRNA expression levels of DAZL and UTF-1 were significantly different in both groups. Interestingly, the im-munolabeling and the relative mRNA expression of PGP9.5 were significantly different between BS and NBS. From these results, it is hypothesized that the expression level of these putative molecular markers might be gonadotropin-dependent in stallion testes.(c) 2022 Elsevier Inc. All rights reserved. | Shakeel, Muhammad; Jung, Heejun; Yoon, Duhak; Yoon, Minjung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, South Korea; Kyungpook Natl Univ, Dept Horse Compan & Wild Anim Sci, Sangju 37224, South Korea; Kyungpook Natl Univ, Res Ctr Horse Ind, Sangju 37224, South Korea; Pir Mehr Ali Shah Arid Agr Univ, Fac Vet & Anim Sci, Dept Clin Studies, Rawalpindi 44000, Pakistan; Kyungpook Natl Univ, Dept Horse Compan & Wild Anim Sci, Sangju, South Korea | 57209179360; 56374279800; 7202875754; 22137296500 | mjyoonemail@gmail.com; | JOURNAL OF EQUINE VETERINARY SCIENCE | J EQUINE VET SCI | 0737-0806 | 1542-7412 | 118 | SCIE | VETERINARY SCIENCES | 2022 | 1.3 | 49.7 | 1.33 | 2025-06-25 | 6 | 6 | spermatogonial stem cell; molecular marker; immunohistochemistry; infertility; mRNA expression | FAMILY PROTEINS; C-KIT; DAZL; QUALITY; TESTES; UTF1; GENE; SPERMATOGONIA; CULTURE; BINDING | immunohistochemistry; infertility; molecular marker; mRNA expression; spermatogonial stem cell | Animals; Biomarkers; Horses; Male; Proteins; RNA, Messenger; Seasons; Semen; Spermatogonia; Testis; deleted in azoospermia protein 1; gonadotropin; messenger RNA; molecular marker; biological marker; messenger RNA; protein; animal experiment; animal model; antibody labeling; Article; controlled study; gene product; germ cell; histopathology; immunohistochemistry; male; male infertility; mRNA expression level; nonhuman; quantitative analysis; real time reverse transcription polymerase chain reaction; seasonal variation; seminiferous tubule; spermatogenesis; spermatogonium; stallion; subfertility; testis tissue; animal; genetics; horse; metabolism; season; sperm; spermatogonium; testis | English | 2022 | 2022-11 | 10.1016/j.jevs.2022.104109 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles | BACKGROUND Dermal papillae (DP) and outer root sheath (ORS) cells play important roles in hair growth and regeneration by regulating the activity of hair follicle (HF) cells. AIM To investigate the effects of human mesenchymal stem cell-derived extracellular vesicles (hMSC-EVs) on DP and ORS cells as well as HFs. EVs are known to regulate various cellular functions. However, the effects of hMSC-EVs on hair growth, particularly on human-derived HF cells (DP and ORS cells), and the possible mechanisms underlying these effects are unknown. METHODS hMSC-EVs were isolated and characterized using transmission electron micro scopy, nanoparticle tracking analysis, western blotting, and flow cytometry. The activation of DP and ORS cells was analyzed using cellular proliferation, migration, western blotting, and real-time polymerase chain reaction. HF growth was evaluated ex vivo using human HFs. RESULTS Wnt3a is present in a class of hMSC-EVs and associated with the EV membrane. hMSC-EVs promote the proliferation of DP and ORS cells. Moreover, they translocate beta-catenin into the nucleus of DP cells by increasing the expression of beta-catenin target transcription factors (Axin2, EP2 and LEF1) in DP cells. Treatment with hMSC-EVs also promoted the migration of ORS cells and enhanced the expression of keratin (K) differentiation markers (K6, K16, K17, and K75) in ORS cells. Furthermore, treatment with hMSC-EVs increases hair shaft elongation in cultured human HFs. CONCLUSION These findings suggest that hMSC-EVs are potential candidates for further preclinical and clinical studies on hair loss treatment. | Rajendran, Ramya Lakshmi; Gangadaran, Prakash; Kwack, Mi Hee; Oh, Ji Min; Hong, Chae Moon; Sung, Young Kwan; Lee, Jaetae; Ahn, Byeong-Cheol | Kyungpook Natl Univ, Sch Med, Dept Nucl Med, 680 Gukchaebosangro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 FOUR KNU Convergence Educ Program Biomed Sci, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Immunol, Daegu 41944, South Korea; Kyungpook Natl Univ Hosp, Dept Nucl Med, Daegu 41944, South Korea | Gangadaran, Prakash/AAV-3102-2021; Rajendran, Ramya/AAV-6338-2021 | 57195318729; 54393130400; 6507685557; 57190370462; 37050876700; 55663365300; 7601451907; 7202791511 | abc2000@knu.ac.kr; | WORLD JOURNAL OF STEM CELLS | WORLD J STEM CELLS | 1948-0210 | 14 | 7 | SCIE | CELL & TISSUE ENGINEERING;CELL BIOLOGY | 2022 | 4.1 | 50.0 | 0.92 | 2025-06-25 | 9 | 9 | Mesenchymal stem cells; Extracellular vesicles; Hair growth; Dermal papillae; Outer root sheath cells | PAPILLA CELLS | Dermal papillae; Extracellular vesicles; Hair growth; Mesenchymal stem cells; Outer root sheath cells | ataxin 2; beta catenin; keratin; lymphoid enhancer factor 1; alopecia; androgenic alopecia; Article; cell activation; cell differentiation; cell function; cell migration; cell migration assay; cell proliferation; cell proliferation assay; confocal microscopy; controlled study; ex vivo study; exosome; flow cytometry; hair; hair follicle; hair growth; hair transplantation; human; human cell; immunofluorescence assay; internalization (cell); mesenchymal stem cell; outer hair cell; papillary dermis; phase contrast microscopy; real time polymerase chain reaction; skin cell; transmission electron microscopy; Western blotting | English | 2022 | 2022-07-26 | 10.4252/wjsc.v14.i7.527 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical adaptation of synthetic MRI-based whole brain volume segmentation in children at 3 T: comparison with modified SPM segmentation methods | Purpose To validate the use of synthetic magnetic resonance imaging (SyMRI) volumetry by comparing with child-optimized SPM 12 volumetry in 3 T pediatric neuroimaging. Methods In total, 106 children aged 4.7-18.7 years who underwent both synthetic and 3D T1-weighted imaging and had no abnormal imaging/neurologic findings were included for the SyMRI vs. SPM T1-only segmentation (SPM T1). Forty of the 106 children who underwent an additional 3D T2-weighted imaging were included for the SyMRI vs. SPM multispectral segmentation (SPM multi). SPM segmentation using an age-appropriate atlas and inverse-transforming template-space intracranial mask was compared with SyMRI segmentation. Volume differences between SyMRI and SPM T1 were plotted against age to evaluate the influence of age on volume difference. Results Measurements derived from SyMRI and two SPM methods showed excellent agreements and strong correlations except for the CSF volume (CSFV) (intraclass correlation coefficients = 0.87-0.98; r = 0.78-0.96; relative volume difference other than CSFV = 6.8-18.5% [SyMRI vs. SPM T1] and 11.3-22.7% [SyMRI vs. SPM multi]). Dice coefficients of all brain tissues (except CSF) were in the range 0.78-0.91. The Bland-Altman plot and age-related volume difference change suggested that the volume differences between the two methods were influenced by the volume of each brain tissue and subject's age (p < 0.05). Conclusion SyMRI and SPM segmentation results were consistent except for CSFV, which supports routine clinical use of SyMRI-based volumetry in pediatric neuroimaging. However, caution should be taken in the interpretation of the CSF segmentation results. | Lee, So Mi; Kim, Eunji; You, Sun Kyoung; Cho, Hyun-Hae; Hwang, Moon Jung; Hahm, Myong-Hun; Cho, Seung Hyun; Kim, Won Hwa; Kim, Hye Jung; Shin, Kyung Min; Park, Byunggeon; Chang, Yongmin | Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu, South Korea; Kyungpook Natl Univ, Dept Radiol, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Dept Med & Biol Engn, Daegu, South Korea; Chungnam Natl Univ, Chungnam Natl Univ Hosp, Dept Radiol, Coll Med, Daejeon, South Korea; Ewha Womans Univ, Coll Med, Dept Radiol, Anyangcheon Ro 1071, Seoul 07985, South Korea; Ewha Womans Univ, Coll Med, Med Res Inst, Anyangcheon Ro 1071, Seoul 07985, South Korea; Gen Elect GE Healthcare Korea, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Mol Med, 130 Dongdeok Ro, Daegu 41944, South Korea | 56824903400; 57215273419; 56710939300; 56544900900; 57200114449; 56015548700; 55686242700; 36081886500; 57203506201; 7402410737; 57211532915; 7501840633 | ychang@knu.ac.kr; | NEURORADIOLOGY | NEURORADIOLOGY | 0028-3940 | 1432-1920 | 64 | 2 | SCIE | CLINICAL NEUROLOGY;NEUROIMAGING;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2022 | 2.8 | 50.0 | 0.62 | 2025-06-25 | 5 | 5 | Synthetic MRI; SPM; Children; Brain segmentation; Multispectral segmentation | INTRACRANIAL VOLUME; TISSUE; QUANTIFICATION; IMAGES | Brain segmentation; Children; Multispectral segmentation; SPM; Synthetic MRI | adolescent; adult; Article; brain size; brain tissue; cerebrospinal fluid; child; controlled study; female; gray matter volume; human; image analysis; image segmentation; intermethod comparison; major clinical study; male; neuroimaging; neurologic disease; nuclear magnetic resonance imaging; segmentation algorithm; T1 weighted imaging; T2 weighted imaging; volumetry; white matter | English | 2022 | 2022-02 | 10.1007/s00234-021-02779-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Comparative studies on physicochemical properties of rice with germinated dark purple giant embryo rice and normal embryo rice | Background and objectives As a cultivar developed by breeding, pigmented rice Keunnunjami has a dark purple pericarp and a giant embryo and has been found to possess strong antioxidant properties. The present study investigated the effect of 72-hr germination on the physicochemical properties of Keunnunjami, in comparison with that of its parental pigmented normal embryo cultivar, Heukjinju, and ordinary normal brown rice. Findings Germination generally increased the amounts of reducing sugar, amino acids isoleucine, leucine, phenylalanine, valine, alanine, cysteine, glycine, proline, and tyrosine, and minerals such as calcium, magnesium, and phosphorus while it decreased the levels of histidine, lysine, methionine, threonine, arginine, aspartic acid, glutamic acid, serine, and potassium in the rice grains. The germinated Keunnujami exhibited higher amounts of essential and non-essential amino acids and reducing sugar than the germinated Heukjinju and normal brown rice. The starch granules from all rice samples showed holes and pits on the surface after germination. Conclusions These changes in the chemical composition and morphological properties are possibly due to partial hydrolysis of starch and protein caused by enzymes that were activated during germination. Significance and novelty Results of this study could serve as the baseline information for evaluating the quality and possible food industry applications of germinated Keunnunjami. | Chung, Soo Im; Kang, Mi Young | Kyungpook Natl Univ, Ctr Food & Nutr Genom Res, Daegu, South Korea; Kyungpook Natl Univ, Dept Food Sci & Nutr, Daegu, South Korea | Kim, Eun-Young/GQQ-0147-2022 | 39862602700; 7401549322 | mykang@knu.ac.kr; | CEREAL CHEMISTRY | CEREAL CHEM | 0009-0352 | 1943-3638 | 99 | 2 | SCIE | CHEMISTRY, APPLIED;FOOD SCIENCE & TECHNOLOGY | 2022 | 2.4 | 50.0 | 0.28 | 2025-06-25 | 3 | 3 | chemical composition; germination; Keunnunjami; pigmented rice; starch | BROWN RICE; BRAN EXTRACTS; STARCH; DIGESTIBILITY; COMPONENTS | chemical composition; germination; Keunnunjami; pigmented rice; starch | Amino acids; Cultivation; Grain (agricultural product); Physicochemical properties; Starch; Antioxidant properties; Brown rice; Chemical compositions; Comparatives studies; Keunnunjami; Methionine; Physicochemical property; Pigmented rice; Reducing sugars; Sugar amino acids; Germination | English | 2022 | 2022-03 | 10.1002/cche.10483 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Comparison of Efficacy and Safety of Statin-Ezetimibe Combination Therapy with Statin Monotherapy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Studies | Introduction Dyslipidemia in diabetes mellitus is characterized by hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), and elevated low-density lipoprotein cholesterol (LDL-C). Additionally, the potentially increased risk of morbidity and mortality following atherosclerotic cardiovascular diseases should be considered in the treatment of dyslipidemia in patients with diabetes. Methods We performed a meta-analysis of the published data to compare the effects of HMG-CoA reductase inhibitor (statin)-ezetimibe combination therapy and statin monotherapy on lipid and glucose parameters in patients with diabetes. We also compared safety based on the adverse events reported for the two groups. Results In total, 17 articles were included in this meta-analysis. In the efficacy assessment, the combination treatment afforded a significantly greater reduction in LDL-C than did statin monotherapy (standard difference in means 0.691; 95% confidence interval 0.534-0.847). A significantly greater improvement effect was observed in the levels of HDL-C, total cholesterol, triglyceride, and apolipoprotein B, but not apolipoprotein A1, with combination therapy than with statin monotherapy. Additionally, combination therapy reduced fasting blood glucose levels more significantly than did statin monotherapy. In terms of safety, there were no significant differences in treatment-related adverse events between the two treatments. Conclusions Statin-ezetimibe combination therapy enhances levels of LDL-C and other lipids without increasing the risk of adverse events compared with statin monotherapy. The present meta-analysis presents valid evidence for appropriate drug regimens to treat dyslipidemia in patients with diabetes. Registration PROSPERO Identifier Number CRD42021244578 | Shin, Kwang-Hee; Choi, Hye Duck | Kyungpook Natl Univ, Coll Pharm, Res Inst Pharmaceut Sci, Daegu, South Korea; Yeungnam Univ, Coll Pharm, Gyongsan, Gyeongbuk, South Korea | 35216279300; 36877353300 | chd80@hotmail.com; | AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS | AM J CARDIOVASC DRUG | 1175-3277 | 1179-187X | 22 | 4 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS;PHARMACOLOGY & PHARMACY | 2022 | 3 | 50.0 | 0.36 | 2025-06-25 | 6 | 6 | ATORVASTATIN 20 MG; EZETIMIBE/SIMVASTATIN 10/20; GLYCEMIC CONTROL; CLINICAL-TRIALS; LIPID PROFILE; CHOLESTEROL; MELLITUS; SIMVASTATIN; LIPOPROTEIN; INTESTINE | Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Diabetes Mellitus; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Treatment Outcome; apolipoprotein A1; apolipoprotein B; atorvastatin; ezetimibe; fluindostatin; glucose; hemoglobin A1c; high density lipoprotein cholesterol; hydroxymethylglutaryl coenzyme A reductase inhibitor; low density lipoprotein cholesterol; rosuvastatin; simvastatin; triacylglycerol; cholesterol; ezetimibe; hydroxymethylglutaryl coenzyme A reductase inhibitor; hypocholesterolemic agent; low density lipoprotein cholesterol; adult; aged; allergy; carotid artery disease; cholesterol blood level; combination drug therapy; comparative effectiveness; controlled study; diabetes mellitus; drug efficacy; drug safety; drug withdrawal; dyslipidemia; female; gastrointestinal symptom; glucose blood level; human; insulin dependent diabetes mellitus; male; meta analysis; metabolic syndrome X; middle aged; monotherapy; muscle disease; non insulin dependent diabetes mellitus; randomized controlled trial (topic); Review; systematic review; combination drug therapy; diabetes mellitus; treatment outcome | English | 2022 | 2022-07 | 10.1007/s40256-021-00516-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Impact of scanning strategy on the accuracy of complete-arch intraoral scans: a preliminary study on segmental scans and merge methods | PURPOSE. This study investigated the accuracy of full-arch intraoral scans obtained by various scan strategies with the segmental scan and merge methods. MATERIALS AND METHODS. Seventy intraoral scans (seven scans per group) were performed using 10 scan strategies that differed in the segmental scan (1, 2, or 3 segments) and the scanning motion (straight, zigzag, or combined). The three-dimensional (3D) geometric accuracy of scan images was evaluated by comparison with a reference image in an image analysis software program, in terms of the arch shape discrepancies. Measurement parameters were the intermolar distance, interpremolar distance, anteroposterior distance, and global surface deviation. One-way analysis of variance and Tukey honestly significance difference post hoc tests were carried out to compare differences among the scan strategy groups (alpha = .05). RESULTS. The linear discrepancy values of intraoral scans were not different among scan strategies performed with the single scan and segmental scan methods. In general, differences in the scan motion did not show different accuracies, except for the intermolar distance measured under the scan conditions of a 3-segmental scan and zigzag motion. The global surface deviations were not different among all scan strategies. CONCLUSION. The segmental scan and merge methods using two scan parts appear to be reliable as an alternative to the single scan method for full-arch intraoral scans. When three segmental scans are involved, the accuracy of complete arch scan can be negatively affected. | Mai, Hai Yen; Mai, Hang-Nga; Lee, Cheong-Hee; Lee, Kyu-Bok; Kim, So-yeun; Lee, Jae-Mok; Lee, Keun-Woo; Lee, Du-Hyeong | Kyungpook Natl Univ, Sch Dent, Dept Prosthodont, Daegu, South Korea; Kyungpook Natl Univ, Inst Translat Res Dent, Daegu, South Korea; Kyungpook Natl Univ, Dept Periodontol, Sch Dent, Daegu, South Korea; VHS Med Ctr, Seoul, South Korea | ; Mai, Hang-Nga/Q-9865-2018 | 57217872800; 56964780900; 56101128900; 15925571200; 57190972249; 17346330000; 56208733400; 35770948000 | deweylee@knu.ac.kr; | JOURNAL OF ADVANCED PROSTHODONTICS | J ADV PROSTHODONT | 2005-7806 | 2005-7814 | 14 | 2 | SCIE | DENTISTRY, ORAL SURGERY & MEDICINE | 2022 | 2.6 | 50.0 | 7.38 | 2025-06-25 | 19 | 29 | Intraoral scan; Scan strategy; Accuracy; Image stitching; Segmental scan; Scan motion | SCANNERS; IMPRESSIONS; PRECISION; SYSTEMS | Accuracy; Image stitching; Intraoral scan; Scan motion; Scan strategy; Segmental scan | English | 2022 | 2022-04 | 10.4047/jap.2022.14.2.88 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Impact of successful restoration of sinus rhythm in patients with atrial fibrillation and acute heart failure: Results from the Korean Acute Heart Failure registry | Background: Restoring and maintaining sinus rhythm (SR) in patients with atrial fibrillation (AF) failed to show superior outcomes over rate control strategies in prior randomized trials. However, there is sparse data on their outcomes in patients with acute heart failure (AHF). Methods: From December 2010 to February 2014, 5,625 patients with AHF from 10 tertiary hospi- tals were enrolled in the Korean Acute Heart Failure registry, including 1,961 patients whose initial electrocardiogram showed AF. Clinical outcomes of patients who restored SR by pharmacological or electrical cardioversion (SR conversion group, n = 212) were compared to those of patients who showed a persistent AF rhythm (AF persistent group, n = 1,662). Results: All-cause mortality both in-hospital and during the follow-up (median 2.5 years) were sig- nificantly lower in the SR conversion group than in the AF persistent group after adjustment for risk factors (adjusted hazard ratio [HR]; 95% confidence interval [CI] = 0.26 [0.08-0.88], p = 0.031 and 0.59 [0.43-0.82], p = 0.002, for mortality in-hospital and during follow-up, respectively). After 1:3 propensity score matching (SR conversion group = 167, AF persistent group = 501), successful restoration of SR was associated with lower all-cause mortality (HR [95% CI] = 0.68 [0.49-0.93], p = 0.015), heart failure rehospitalization (HR [95% CI] = 0.66 [0.45-0.97], p = 0.032), and compos- ite of death and heart failure rehospitalization (HR [95% CI] = 0.66 [0.51-0.86], p = 0.002). Conclusions: Patients with AHF and AF had significantly lower mortality in-hospital and during follow-up if rhythm treatment for AF was successful, underscoring the importance of restoring SR in with AHF. (Cardiol J 2022; 29, 3: 472-480) | Cho, Youngjin; Oh, Il-Young; Park, Jin Joo; Oh, Byung-Hee; Jeon, Eun-Seok; Kim, Jae-Joong; Hwang, Kyung-Kuk; Cho, Myeong-Chan; Chae, Shung Chull; Baek, Sang Hong; Kang, Seok-Min; Yoo, Byung-Su; Ahn, Youngkeun; Choi, Dong-Ju | Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Sungkyunkwan Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Univ Ulsan, Dept Internal Med, Coll Med, Seoul, South Korea; Chungbuk Natl Univ, Dept Internal Med, Coll Med, Cheongju, South Korea; Kyungpook Natl Univ, Dept Internal Med, Coll Med, Daegu, South Korea; Catholic Univ Korea, Dept Internal Med, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Wonju Coll Med, Wonju, South Korea; Chonnam Natl Univ, Dept Internal Med, Heart Res Ctr, Gwangju, South Korea | ; Oh, Byung-Hee/G-9875-2011; Choi, Dong-Ju/J-5686-2012; Oh, Il-Young/ACC-0418-2022; Jeong, Gi/AAB-2830-2021 | 56313472800; 8724022000; 35799900000; 57216293873; 7004279641; 36065764100; 7402426370; 7401727518; 7101962036; 7201371594; 7405685375; 7102851884; 56937721300; 35274349200 | djchoi@snubh.org; | CARDIOLOGY JOURNAL | CARDIOL J | 1897-5593 | 1898-018X | 29 | 3 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2022 | 3 | 50.0 | 0.23 | 2025-06-25 | 3 | 3 | atrial fibrillation; acute heart failure; cardioversion | CATHETER ABLATION; MORTALITY; MANAGEMENT; THERAPY; TRIAL; RISK | acute heart failure; atrial fibrillation; cardioversion | Atrial Fibrillation; Electric Countershock; Heart Failure; Humans; Registries; Republic of Korea; Treatment Outcome; angiotensin receptor antagonist; beta adrenergic receptor blocking agent; brain natriuretic peptide; creatinine; hemoglobin; acute heart failure; acute heart infarction; adult; aged; all cause mortality; Article; artificial ventilation; atrial fibrillation; biochemistry; cerebrovascular disease; CHA2DS2 VAS score; chronic kidney failure; clinical outcome; cohort analysis; electrocardiogram; electrocardiography; female; follow up; heart failure; heart restoration; hospital mortality; hospital outcome; hospital readmission; hospitalization; human; hypertension; ischemic heart disease; laboratory test; major clinical study; male; medical procedures; multicenter study; outcome assessment; propensity score; sinus rhythm; tachycardia; tertiary care center; valvular heart disease; atrial fibrillation; cardioversion; complication; epidemiology; heart failure; register; South Korea; treatment outcome | English | 2022 | 2022-05 | 10.5603/cj.a2020.0103 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Alterations of Functional Connectivity in Patients With Restless Legs Syndrome | Restless legs syndrome (RLS) is a common neurological illness marked by a strong desire to move one's legs, usually in association with uncomfortable sensations. Recent studies have investigated brain networks and connectivity in RLS. The advent of network analysis has greatly improved our understanding of the brain and various neurological disorders. A few studies have investigated alterations in functional connectivity in patients with RLS. This article reviews functional connectivity studies of patients with RLS, which have identified significant alterations relative to healthy controls in several brain networks including thalamic, salience, default-mode, and small-world networks. In addition, network changes related to RLS treatment have been found, including to repetitive transcranial magnetic stimulation, transcutaneous spinal cord direct-current stimulation, and dopaminergic drugs. These findings suggest that the underlying pathogenesis of RLS includes alterations in the functional connectivity in the brain and that RLS is a network disorder. | Park, Kang Min; Kim, Keun Tae; Kang, Kyung Wook; Park, Jung A.; Seo, Jong-Geun; Kim, Jiyoung; Chang, Hyeyeon; Kim, Eun Young; Cho, Yong Won | Inje Univ, Haeundae Paik Hosp, Dept Neurol, Coll Med, Busan, South Korea; Keimyung Univ, Dept Neurol, Sch Med, 1095 Dalgubeoldae Ro, Daegu 42601, South Korea; Chonnam Natl Univ Hosp, Dept Neurol, Gwangju, South Korea; Daegu Catholic Univ, Dept Neurol, Med Ctr, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurol, Daegu, South Korea; Pusan Natl Univ, Dept Neurol, Sch Med, Busan, South Korea; Konyang Univ, Dept Neurol, Sch Med, Daejeon, South Korea; Chungnam Natl Univ, Dept Neurol, Sejong Hosp, Sejong, South Korea | ; Kim, Keun Tae/IQU-1105-2023; Kim, Eun Young/KWU-6580-2024 | 55676211700; 57204465615; 57211333312; 57225162068; 16040307500; 57190768301; 59830570400; 58600592200; 55080335000 | neurocho@gmail.com; | JOURNAL OF CLINICAL NEUROLOGY | J CLIN NEUROL | 1738-6586 | 2005-5013 | 18 | 3 | SCIE | CLINICAL NEUROLOGY | 2022 | 3.1 | 50.2 | 0.87 | 2025-06-25 | 14 | 15 | restless legs syndrome; brain; magnetic resonance imaging | DIRECT-CURRENT STIMULATION; DEFAULT MODE NETWORK; DIAGNOSTIC-CRITERIA | Brain; Magnetic resonance imaging; Restless legs syndrome | dopamine receptor stimulating agent; default mode network; functional connectivity; functional magnetic resonance imaging; human; International Restless Legs Syndrome Study Group Rating Scale; nuclear magnetic resonance imaging; repetitive transcranial magnetic stimulation; resting state network; restless legs syndrome; Review; salience network; small world network; thalamic network | English | 2022 | 2022-05 | 10.3988/jcn.2022.18.3.290 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical Usefulness of Simultaneous Electroencephalography and Functional Magnetic Resonance Imaging in Children With Focal Epilepsy | Background and Purpose The current study analyzed the interictal epileptiform discharge (IED)-related hemodynamic response and aimed to determine the clinical usefulness of simultaneous electroencephalography and functional magnetic resonance imaging (EEG-fMRI) in defining the epileptogenic zone (EZ) in children with focal epilepsy. Methods Patients with focal epilepsy showing IEDs on conventional EEG were evaluated using EEG-fMRI. Statistical analyses were performed using the times of spike as events modeled with multiple hemodynamic response functions. The area showing the most significant t-value for blood-oxygen-level-dependent (BOLD) changes was compared with the presumed EZ. Moreover, BOLD responses between -9 and +9 s around the spike times were analyzed to track the hemodynamic response patterns over time. Results Half (n=13) of 26 EEG-fMRI investigations of 19 patients were successful. Two patients showed 2 different types of spikes, resulting in 15 analyses. The maximum BOLD response was concordant with the EZ in 11 (73.3%) of the 15 analyses. In 10 (66.7%) analyses, the BOLD response localized the EZs more specifically. Focal BOLD responses in the EZs occurred before IEDs in 11 analyses and were often widespread after IEDs. Hemodynamic response patterns were consistent in the same epilepsy syndrome or when repeating the investigation in the same patients. Conclusions EEG-fMRI can provide additional information for localizing the EZ in children with focal epilepsy, and also reveal the pathogenesis of pediatric epilepsy by evaluating the patterns in the hemodynamic response across time windows of IEDs. | Lee, Yun Jeong; Bae, Hyunwoo; Byun, Jun Chul; Kwon, Soonhak; Oh, Sung Suk; Kim, Saeyoon | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Pediat, Daegu, South Korea; Keimyung Univ, Dongsan Hosp, Sch Med, Dept Pediat, Daegu, South Korea; Daegu Gyeongbuk Med Innovat Fdn K MEDI Hub, Med Device Dev Ctr, Daegu, South Korea; Yeungnam Univ, Med Ctr, Coll Med, Dept Pediat, Daegu, South Korea | Bae, Hyunwoo/LMN-7326-2024 | 55978748900; 57877451300; 55671798400; 55468232200; 57193393986; 53984438900 | ssoh@kmedihub.re.kr;sysnow88@hanmail.net; | JOURNAL OF CLINICAL NEUROLOGY | J CLIN NEUROL | 1738-6586 | 2005-5013 | 18 | 5 | SCIE | CLINICAL NEUROLOGY | 2022 | 3.1 | 50.2 | 0.11 | 2025-06-25 | 1 | 1 | electroencephalography; functional magnetic resonance imaging; child; focal epilepsy | EEG-FMRI; HEMODYNAMIC-RESPONSE; SPIKES; LOCALIZATION; DISCHARGES; ACTIVATION; SPECT; MRI; VARIABILITY; SENSITIVITY | child; electroencephalography; focal epilepsy; functional magnetic resonance imaging | English | 2022 | 2022-09 | 10.3988/jcn.2022.18.5.535 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Letter | Statin-Induced Immune-Mediated Necrotizing Myopathy Does Not Always Present With Immediate or Severe Symptoms | Kang, Minsung; Park, Young-Eun; Shin, Jin-Hong; Seok, Hung Youl | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurol, Daegu, South Korea; Pusan Natl Univ Hosp, Dept Neurol, Busan, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Neurol, Yangsan, South Korea; Keimyung Univ, Sch Med, Dongsan Med Ctr, Dept Neurol, 1035 Dalgubeol Daero, Daegu 42601, South Korea | Shin, Jin-Hong/AAZ-8809-2020; Seok, Hung Youl/HZI-4365-2023 | 57719257600; 7405375250; 36538204000; 24472118000 | shy2354@gmail.com; | JOURNAL OF CLINICAL NEUROLOGY | J CLIN NEUROL | 1738-6586 | 2005-5013 | 18 | 4 | SCIE | CLINICAL NEUROLOGY | 2022 | 3.1 | 50.2 | 0.96 | 2025-06-25 | 2 | 2 | MYOSITIS | acid phosphatase; anti hmgcr antibody; autoantibody; creatine kinase; methylprednisolone; rosuvastatin; unclassified drug; action potential; adult; autoimmune profiling; biceps brachii muscle; bilateral thigh muscle; case report; clinical article; clinical feature; clinical observation; diffuse hyperintense t2 weighted signals; drug withdrawal; hip flexion; human; human tissue; hyperlipidemia; immunoassay; laboratory test; left vastus lateralis; Letter; middle aged; muscle biopsy; muscle fiber size; muscle weakness; musculoskeletal system parameters; myopathy; needle electromyography; nerve conduction; neurologic examination; nuclear magnetic resonance imaging; physical parameters; polyphasic motor unit potential; polyphasic motor unit potentials with short duration; polyphasic motor unit potentials with small amplitude; positive sharp wave of right biceps; proximal weakness of lower extremity; proximal weakness of upper extremity; radiological parameters; rectus femoris muscle; sensory system; slight weakness in shoulder abduction; statin induced immune mediated necrotizing myopathy; T2 weighted imaging; tendon reflex; thyroid function | English | 2022 | 2022-07 | 10.3988/jcn.2022.18.4.489 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Effects of Aging Methods and Periods on Quality Characteristics of Beef | The objective of this study was to determine effects of aging methods (wet -aged, dry-aged, and packaged dry-aged) during 60 d on quality traits and microbial characteristics of beef. Wet-aged beef was packed by vacuum packaging and stored in a 4 degrees C refrigerator. Dry-aged beef was used without packaging. Packaged dry-aged beef was packaged in commercial bags. Dry-aged and packaged dry-aged samples were stored in a meat ager at 2 degrees C-4 degrees C with 85%-90% relative humidity. Meat color, crust thickness, aging loss, cooking loss, Warner-Bratzler shear force (WBSF), texture profile analysis, Torrymeter, meat pH, water activity, volatile basic nitrogen (VBN), thiobarbituric acid reactant substances (TBARS), and microbial analysis were measured or performed every 15 d until 60 d of aging time. Meat color changed significantly with increasing aging time. Differences in meat color among aging methods were observed. Aging losses of dry-aged and packaged dry-aged samples were higher than those of wet-aged samples. Wet-aged beef showed higher cooking loss, but lower WBSF than dry-aged and packaged dry-aged beef. VBN and TBARS showed an increasing tendency with increasing aging time. Differences of VBN and TBARS among aging methods were found. Regarding microbial analysis, counts of yeasts and molds were different among aging methods at the initial aging time. Packaged dry-aged and dry-aged beef showed similar values or tendency. Significant changes occurred during aging in all aging methods. Packaged dry aging and dry aging could result in similar quality traits and microbial characteristics of beef. | Kim, SolJi; Kim, GwangHeun; Moon, Chan; Ko, KyoungBo; Choi, YoungMin; Choe, JeeHwan; Ryu, YounChul | Jeju Natl Univ, SARI, Div Biotechnol, Jeju 63243, South Korea; Kyungpook Natl Univ, Dept Anim Sci, Sangju 37224, South Korea; Korea Natl Univ Agr & Fisheries, Dept Livestock, Major Beef Sci, Jeonju 54874, South Korea | 57985369800; 57984480800; 57985013300; 59122334100; 57226673843; 26631522600; 7103412014 | jchoe@korea.kr;ycryu@jejunu.ac.kr; | FOOD SCIENCE OF ANIMAL RESOURCES | FOOD SCI ANIM RESOUR | 2636-0772 | 2636-0780 | 42 | 6 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2022 | 3 | 50.4 | 2.5 | 2025-06-25 | 21 | 19 | dry aging methods; long-term aging; microbial safety; packaged dry-aged beef | DRY-AGED BEEF; LIPID OXIDATION; MEAT; TENDERIZATION; PALATABILITY; STEAKS; TIME; PORK; BAG | dry aging methods; long-term aging; microbial safety; packaged dry-aged beef | English | 2022 | 2022 | 10.5851/kosfa.2022.e63 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Asymmetric Contribution of Blastomere Lineages of First Division of the Zygote to Entire Human Body Using Post-Zygotic Variants | Background: In humans, after fertilization, the zygote divides into two 2n diploid daughter blastomeres. During this division, DNA is replicated, and the remaining mutually exclusive genetic mutations in the genome of each cell are called post-zygotic variants. Using these somatic mutations, developmental lineages can be reconstructed. How these two blastomeres are contributing to the entire body is not yet identified. This study aims to evaluate the cellular contribution of two blastomeres of 2-cell embryos to the entire body in humans using post-zygotic variants based on whole genome sequencing. Methods: Tissues from different anatomical areas were obtained from five donated cadavers for use in single-cell clonal expansion and bulk target sequencing. After conducting whole genome sequencing, computational analysis was applied to find the early embryonic mutations of each clone. We developed our in-house bioinformatics pipeline, and filtered variants using strict criteria, composed of mapping quality, base quality scores, depth, soft-clipped reads, and manual inspection, resulting in the construction of embryological phylogenetic cellular trees. Results: Using our in-house pipeline for variant filtering, we could extract accurate true positive variants, and construct the embryological phylogenetic trees for each cadaver. We found that two daughter blastomeres, L1 and L2 (lineage 1 and 2, respectively), derived from the zygote, distribute unequally to the whole body at the clonal level. From bulk target sequencing data, we validated asymmetric contribution by means of the variant allele frequency of L1 and L2. The asymmetric contribution of L1 and L2 varied from person to person. Conclusion: We confirmed that there is asymmetric contribution of two daughter blastomeres from the first division of the zygote across the whole human body. | Kwon, Seong Gyu; Bae, Geon Hue; Choi, June Hyug; Mali, Nanda Maya; Jun, Mee Sook; Kim, Dong Sun; Han, Man-Hoon; Park, Seongyeol; Ju, Young Seok; Choi, Seock Hwan; Oh, Ji Won | Kyungpook Natl Univ, Sch Med, Dept Anat, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, BK21 Plus KNU Biomed Convergence Program, Daegu, South Korea; Kyungpook Natl Univ Hosp, Biomed Res Inst, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pathol, Daegu, South Korea; Korea Adv Inst Sci & Technol KAIST, Grad Sch Med Sci & Engn GSMSE, Daejeon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Yonsei Univ, Dept Anat, Coll Med, Seoul, South Korea | ; Ju, Young Seok/E-1324-2012; Ju, Young/E-1324-2012; Oh, Ji/AAZ-3153-2020; Kim, Dae/AAJ-7518-2021 | 57221465679; 57578938100; 57195986324; 57195987350; 7006544857; 57125070500; 57194067936; 56488636200; 25947457600; 9742645500; 36093206200 | skhwan.script@gmail.com;G1@yuhs.ac; | TISSUE ENGINEERING AND REGENERATIVE MEDICINE | TISSUE ENG REGEN MED | 1738-2696 | 2212-5469 | 19 | 4 | SCIE | CELL & TISSUE ENGINEERING;ENGINEERING, BIOMEDICAL | 2022 | 3.6 | 50.5 | 0.11 | 2025-06-25 | 1 | 1 | Clonal expansion; Somatic mutation; Lineage tracing; Asymmetry; Early embryonic mutations; Mutation filtering | PREIMPLANTATION GENETIC DIAGNOSIS; BLASTOCYST BIOPSY; MOUSE; EMBRYOS; CELLS; IMPLANTATION; SEGREGATION; TOTIPOTENCY; MUTATIONS; FRAMEWORK | Asymmetry; Clonal expansion; Early embryonic mutations; Lineage tracing; Mutation filtering; Somatic mutation | Blastomeres; Human Body; Humans; Phylogeny; Zygote; Clone cells; Cloning; Genes; Phylogenetic; Trees (mathematics); Asymmetry; Cellulars; Clonal expansion; Early embryonic mutation; Embryonics; Human bodies; Lineage tracing; Mutation filtering; Somatic mutation; Whole genome sequencing; allele; article; bioinformatics; blastomere; cadaver; case report; clinical article; embryo; female; filtration; gene frequency; human; human cell; male; phylogenetic tree; pipeline; somatic mutation; whole genome sequencing; zygote; blastoma; phylogeny; Pipelines | English | 2022 | 2022-08 | 10.1007/s13770-022-00443-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Comparative response of two seasonal spotted wing drosophila (Drosophila suzukii) morphs to different classes of insecticides | Drosophila suzukii Matsumura (Drosophilidae) is a devasting invasive pest affecting berry crops and cherry production throughout North America, South America, and Europe. This species has two different morph phenotypes, winter and summer morphs, which are temperature dependent. Chemical control is the most widely used management approach for managing the spotted wing drosophila, D. suzukii. Little is known regarding the differential response of the two seasonal morphs to insecticides. In this study, we identified a high number of differentially expressed genes likely involved in phase I, II, and III of detoxification pathways and other cuticular proteins in winter morphs as compared to summer morphs. Specifically, several detoxification genes (phase I: Cyp4e3, Cyp4s3, Cyp6d5, Cyp49a1, Cyp318a1; phase II: GstD10, Ugt35Bb, Ugt37b1, Ugt58Fa; phase III: Mdr65) were overexpressed more than two-fold in winter morph. Additionally, we determined the median lethal concentration, LC50, values of Malathion, Cyantraniliprole, Imidan, Zeta-cypermethrin, and Spinetoram insecticides to compare the insecticide susceptibility against two seasonal morphs of D. suzukii. For most of the pesticides tested, there were no differences between the LC50 values, between summer and winter morphs, however, we found that winter morph exhibited an LC50 value of Spinetoram 3.7-fold, significantly higher than that of the summer morph. Overall, we demonstrated that seasonally induced different morphological phenotypes may result in different transcriptional response of phases I, II, and III of the detoxification pathways and other cuticular proteins. However, we found different responses to at least one insecticide, Spinetoram. It remains to be determined what are underlying physiological differences that lead to these changes in response to Spinetoram. | Seong, Keon Mook; Sun, Weilin; Huang, Juan; Gut, Larry; Kim, Young Ho; Pittendrigh, Barry R. | Chungnam Natl Univ, Dept Appl Biol, Daejeon, South Korea; Purdue Univ, Dept Entomol, Lafayette, IN USA; Michigan State Univ, Dept Entomol, E Lansing, MI USA; Kyungpook Natl Univ, Dept Ecol Sci, Sangju, South Korea | Kim, Young/J-5414-2012; Sun, Wei Lin/JMB-5547-2023 | 59672065600; 55726591200; 35274880500; 6602523315; 58516491300; 59853281200 | kseong6@cnu.ac.kr; | ENTOMOLOGICAL RESEARCH | ENTOMOL RES | 1738-2297 | 1748-5967 | 52 | 11 | SCIE | ENTOMOLOGY | 2022 | 1.3 | 50.5 | 0.58 | 2025-06-25 | 3 | 3 | differentially expressed genes; Drosophila suzukii; resistance management; seasonal polymorphism | ECONOMIC-ANALYSIS; REVENUE LOSSES; TEMPERATURES; MATSUMURA | differentially expressed genes; Drosophila suzukii; resistance management; seasonal polymorphism | English | 2022 | 2022-11 | 10.1111/1748-5967.12624 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Effects of urbanization on carabid beetles in an urban riparian area | Urban rivers and riparian areas serve as corridors that move matter, organisms, and energy to urban areas from adjacent landscapes. However, anthropogenic disturbances and obstructions in river basins have severely impeded the function of many urban rivers as ecological corridors. Here, we used carabid beetles to assess the impact of urbanization on a river and its riparian areas. We identified carabid diversity and composition along an urbanization gradient. We classified 1,855 individuals in 17 species along a river. The carabid communities in riparian areas reflected critically disturbed habitats, and their composition markedly differed between the riparian areas and their adjacent habitats. Carabid beetle diversity sharply decreased with increasing urbanization. Flight capacity and feeding type varied along the urbanization gradient. Environmental variables associated with urbanization such as riparian quality and disturbance level significantly influenced carabid diversity. Land use type in increasingly urbanized areas was correlated with decreased carabid diversity and increased carabid dominance. Patch density, patch size, and interspersion metrics revealed that fragmentation and isolation influenced carabid diversity. Mitigation of disturbances and conservation of riparian microhabitats are required to improve biodiversity in riparian areas. | Do, Yuno; Choi, Moon Bo | Kongju Natl Univ, Dept Biol Sci, Gongju, South Korea; Kyungpook Natl Univ, Inst Plant Med, Daegu, South Korea; Kyungpook Natl Univ, Coll Agr & Life Sci, Dept Plant Protect & Quarantine, Daegu 41566, South Korea | 52163435800; 51863232400 | kosinchoi@hanmail.net; | ENTOMOLOGICAL RESEARCH | ENTOMOL RES | 1738-2297 | 1748-5967 | 52 | 6 | SCIE | ENTOMOLOGY | 2022 | 1.3 | 50.5 | 0.19 | 2025-06-25 | 1 | 1 | carabid; habitat connectivity; isolation; patchy disturbance; riparian; urbanization | SPECIES RICHNESS; GROUND BEETLES; LAND-USE; ASSEMBLAGES; LANDSCAPES; DIVERSITY; PATTERNS; CONSERVATION; COLEOPTERA; IMPACTS | carabid; habitat connectivity; isolation; patchy disturbance; riparian; urbanization | English | 2022 | 2022-06 | 10.1111/1748-5967.12601 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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