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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Effect of Serial Home-Based Exercise Immediately after Latissimus Dorsi Reconstruction in Patients with Breast Cancer | Purpose: This study investigated the effects of a serial home-based exercise program in the affected upper extremity immediately after latissimus dorsi (LD) flap reconstruction with mastectomy in order to improve the functional impairment and quality of life in breast cancer survivors. Methods: Patients with breast cancer scheduled for a mastectomy immediately followed by autologous LD flap reconstruction surgery were enrolled. Forty-five patients were included as an intervention group who received a serial home-based exercise program with stretching and strengthening for upper extremities preoperatively (T0), and 2 weeks (T1), 6 weeks (T2), and 3 months (T3) postoperatively. Thirty-five patients were included as the control group. We evaluated the range of movement in the shoulder at T0, T1, T2, T3, 6 months (T4), and 12 months (T5) postoperatively. We also evaluated the disability of the upper extremity using disabilities of the arm, shoulder, and hand (DASH) questionnaire and quality of life using the 36-Item Short-Form Health Survey (SF-36) at T0, T3, T4, and T5. Results: There were significant differences in interaction effects between time and shoulder flexion and internal and external rotation. Post hoc, the intervention group showed more improvement of movement in internal rotation at T2 and T5 and external rotation at T2, T3, and T4. Furthermore, there were significant differences in interaction effects between DASH scores and time in the two groups. Post hoc, there were significantly lower DASH scores at T3, T4, and T5 in the intervention group. There were significant differences in interaction effects of physical role functioning, vitality, and mental health scores of SF-36 and time in the two groups. Post hoc, physical role functioning scores at T3 and T4 and vitality and mental health scores at T3 were elevated in the intervention group. Conclusion: A serial home-based exercise after LD flap reconstruction is effective for the rehabilitation of the affected upper extremity and enhances the quality of life. | Park, Eunhee; Lee, Joon Seok; Park, Ho Yong; Yang, Jung Dug; Jung, Tae-Du | Kyungpook Natl Univ, Sch Med, Dept Rehabil Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Rehabil Med, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Plast & Reconstruct Surg, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Surg, Chilgok Hosp, Daegu 41404, South Korea | PARK, JUN-YOUNG/P-5981-2015; LEE, JIN/Q-3108-2018; Yang, Jung/R-7806-2019 | 56107216400; 56496041000; 56564377200; 55171704700; 36622364500 | lambyang@knu.ac.kr;teeed0522@knu.ac.kr; | HEALTHCARE | HEALTHCARE-BASEL | 2227-9032 | 10 | 9 | SCIE;SSCI | HEALTH CARE SCIENCES & SERVICES;HEALTH POLICY & SERVICES | 2022 | 2.8 | 48.9 | 0.34 | 2025-06-25 | 3 | 3 | breast neoplasm; mammaplasty; recovery of function; exercise | SHOULDER FUNCTION; KOREAN VERSION; HEALTH SURVEY; FLAP | breast neoplasm; exercise; mammaplasty; recovery of function | English | 2022 | 2022-09 | 10.3390/healthcare10091760 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Effects of an Eye-Tracking Linkage Attention Training System on Cognitive Function Compared to Conventional Computerized Cognitive Training System in Patients with Stroke | Objective: The purpose of the study was to investigate the effects of an eye-tracking linkage attention training system on cognitive function compared to a conventional computerized cognitive training system in stroke patients with cognitive impairment. Methods: This retrospective study was enrolled 40 stroke patients who received cognitive rehabilitation. The intervention consisted of 30 sessions and 30 min per session. Before and after the intervention, we assessed cognitive functions by Mini-Mental State Examination (MMSE-K) and activities of daily living by Modified Barthel Index (K-MBI) and administered a computerized neuropsychological test (CNT). Results: In both groups, there were significant improvements in MMSE-K and K-MBI (p < 0.05). In the visual and auditory attention test of the CNT, the eye-tracking linkage attention training group was significantly improved after intervention (p < 0.05). However, there were no significant differences in the conventional computerized cognitive training group. In addition, there were significant improvements in all memory tests of the CNT in the eye-tracking linkage attention training group. However, in the conventional computerized cognitive training group, there were significant improvements in some memory tests of the CNT. Conclusions: The training of poststroke cognitive impairment patients using an eye-tracking linkage attention training system may improve visuospatial attention and may be helpful for the improvement of short-term memory and independent performances in daily life activities. | Moon, Sung-Jun; Park, Chan-Hee; Jung, Sang In; Yu, Ja-Won; Son, Eun-Chul; Lee, Hye Na; Jeong, Hyeonggi; Jang, Sueun; Park, Eunhee; Jung, Tae-Du | Kyungpook Natl Univ, Dept Rehabil Med, Unit Rehabil Therapy, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ Hosp, Dept Rehabil Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Rehabil Med, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ, Sch Med, Dept Rehabil Med, Daegu 41944, South Korea | 57210988160; 57299095700; 57022688600; 57223965181; 57479985400; 57480676700; 57480541600; 57480261500; 56107216400; 36622364500 | sukusail@naver.com;chany9090@gmail.com;normalman80@gmail.com;jawon0809@naver.com;ironperson@nate.com;lucky167@nate.com;bados1@nate.com;jes3158@naver.com;ehmdpark@knu.ac.kr;teeed0522@knu.ac.kr; | HEALTHCARE | HEALTHCARE-BASEL | 2227-9032 | 10 | 3 | SCIE;SSCI | HEALTH CARE SCIENCES & SERVICES;HEALTH POLICY & SERVICES | 2022 | 2.8 | 48.9 | 0.91 | 2025-06-25 | 7 | 8 | stroke; attention; eye-tracking technology; cognition | IMPAIRMENT; REHABILITATION; MOVEMENTS; PEOPLE; ADL | Attention; Cognition; Eye-tracking technology; Stroke | English | 2022 | 2022-03 | 10.3390/healthcare10030456 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Gluteal Compartment Syndrome and Rhabdomyolysis after Prolonged Laparoscopic Nephroureterectomy and Treatment Strategies Including Rehabilitation: A Case Report | Background: Rhabdomyolysis is a clinical symptom caused by the rapid release of intracellular components such as myoglobin, lactate dehydrogenase, and creatine kinase into the blood circulation. It is commonly caused by muscular injury including compartment syndrome, infection, drugs, etc. Although it rarely occurs during surgery, the incidence may increase if risk factors such as long operation time, improper posture, and condition of being overweight exist. Case Presentation: A 46-year-old male patient complained of pain and weakness in the right hip area and several abnormal findings were observed in the blood sample, reflecting muscle injury and decreased renal function after prolonged urological surgery. He was confirmed as having rhabdomyolysis, which was caused by compartment syndrome of the right gluteal muscle. After the diagnosis, conservative cares were performed in the acute phase and rehabilitation treatments were performed in the chronic phase. After conservative treatment and rehabilitation, blood sample values returned to almost normal ranges and both level of pain and muscle strength were significantly improved. In addition, about 25 days after discharge, he almost recovered to pre-operative condition. Conclusion: Careful attention is required to prevent intraoperative compartment syndrome. It also suggests that not only medical treatment but also early patient-specific rehabilitation is important in patients with rhabdomyolysis after prolonged surgery. | Jeong, Jae-Gyeong; Choi, Seock Hwan; Kim, Ae-Ryoung; Hwang, Jong-Moon | Kyungpook Natl Univ Hosp, Dept Rehabil Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Rehabil Med, Daegu 41944, South Korea | 57222016696; 9742645500; 57196257330; 56367634000 | cloud90524@naver.com;skhwan@gmail.com;ryoung20@hanmail.net;hti82@hanmail.net; | HEALTHCARE | HEALTHCARE-BASEL | 2227-9032 | 10 | 1 | SCIE;SSCI | HEALTH CARE SCIENCES & SERVICES;HEALTH POLICY & SERVICES | 2022 | 2.8 | 48.9 | 0.23 | 2025-06-25 | 2 | 2 | compartment syndrome; rhabdomyolysis; nephroureterectomy; surgery; rehabilitation | RADICAL NEPHRECTOMY; UROLOGIC SURGERY; FLANK POSITION; RISK-FACTORS; DIAGNOSIS; INJURY; PATHOGENESIS | Compartment syndrome; Nephroureterectomy; Rehabilitation; Rhabdomyolysis; Surgery | English | 2022 | 2022-01 | 10.3390/healthcare10010047 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Impaired Affordance Perception as the Basis of Tool Use Deficiency in Alzheimer's Disease | The present study investigated whether defective affordance perception capacity underpins tool use deficits in patients with Alzheimer's disease (AD). An affordance, a concept James Gibson introduced, scales environmental objects to an animal's action capabilities, thus offering opportunities for action. Each man-made artifact carries both a primary affordance (its designed function) and secondary affordances. In Experiment 1, participants identified secondary affordances of objects as a measure of their ability to identify alternative uses of familiar tools. A single response Go/No-Go task was administered to 4 groups: AD, mild cognitive impairment (MCI), Parkinson's disease (PD), and elderly controls (EC). Groups were matched for age and years of education. The AD group performed poorest, followed by MCI, and PD and EC. EC and PD groups' results failed to reach statistical significance, and the AD group performed at chance. In Experiment 2, participants judged the physical properties of the same objects used in Experiment 1. Even AD patients performed reliably, ruling out a visual processing deficit as the basis for their poor performance in Experiment 1. Results suggest that degraded affordance detection capacity can differentiate AD from normal aging and other neurodegenerative disorders and could be an affordable marker for AD, even in the early stages of AD. | Kim, Nam-Gyoon; Effken, Judith A.; Lee, Ho-Won | Keimyung Univ, Dept Psychol, Daegu 42601, South Korea; Univ Arizona, Coll Nursing, Tucson, AZ 85724 USA; Kyungpook Natl Univ, Sch Med, Dept Neurol, Daegu 41404, South Korea | 7403396492; 6603872209; 35337240700 | nk70@kmu.ac.kr;jaeffken@comcast.net;neuromd@knu.ac.kr;k70@kmu.ac.kr; | HEALTHCARE | HEALTHCARE-BASEL | 2227-9032 | 10 | 5 | SCIE;SSCI | HEALTH CARE SCIENCES & SERVICES;HEALTH POLICY & SERVICES | 2022 | 2.8 | 48.9 | 0.23 | 2025-06-25 | 2 | 2 | Alzheimer's disease; affordance; apraxia of tool use; alternative tool use; Go/No-Go task; preclinical stage | MILD COGNITIVE IMPAIRMENT; PARKINSONS-DISEASE; CLINICAL-DIAGNOSIS; IDEOMOTOR APRAXIA; SEMANTIC MEMORY; RECOMMENDATIONS; KNOWLEDGE; DEMENTIA; SYSTEM; BRAIN | affordance; alternative tool use; Alzheimer’s disease; apraxia of tool use; go/no-go task; preclinical stage | English | 2022 | 2022-05 | 10.3390/healthcare10050839 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Satisfaction Factors with a Dental Unit Chair System in South Korea: A Dentist's Perspective | This study aimed to survey users' satisfaction with a dental unit chair in order to highlight the elements affecting the dentist's satisfaction. The questionnaire items were drawn up with seven components that constitute a dental unit chair, including the light, patient seat, foot controller, water fountain and cuspidor, monitor, bracket table and controller, and dentist chair. With these questionnaire elements, a pilot experiment was conducted to test the reliability, and reliability analysis was conducted. The scale reliability was checked using Cronbach's alpha coefficient. Bartlett's test of sphericity, the Kaiser-Meyer-Olkin (KMO) measure, and factor analysis were performed to test whether the items would constitute appropriate questionnaire items for the survey. The survey was conducted with 26 dentists with more than three years of clinical experience. A correlation analysis was conducted using Pearson's correlation coefficient (PCC) (alpha = 0.05) to analyze the impact of the factors on the overall satisfaction with the dental unit chair. The items that were strongly correlated with the overall satisfaction score of the dental unit chair were the design and appearance quality of the dental unit chair (PCC = 0.781), its maintenance (PCC = 0.784), and the overall satisfaction with the water fountain and cuspidor (PCC = 0.703) (p < 0.05). Most of the questionnaire items could affect the overall satisfaction with the dental unit chair. Additionally, because the design and appearance quality, maintenance, and overall satisfaction with the water fountain and cuspidor may have the greatest impact on the overall satisfaction with the dental unit chair, the improvement of these elements may bring about the enhancement of the overall satisfaction. | Son, Keunbada; Son, Young-Tak; Jin, Myoung-Uk; Lee, Kyu-Bok | Kyungpook Natl Univ, Adv Dent Device Dev Inst, Daegu 41940, South Korea; Kyungpook Natl Univ, Grad Sch, Dept Dent Sci, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Conservat Dent, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Prosthodont, Daegu 41940, South Korea | Son, Keunbada/AAG-8089-2019; SON, Keunbada/AAG-8089-2019 | 57202916520; 57219111205; 56492091300; 15925571200 | sonkeunbada@gmail.com;dudxkr741@naver.com;musljin@knu.ac.kr;kblee@knu.ac.kr; | HEALTHCARE | HEALTHCARE-BASEL | 2227-9032 | 10 | 3 | SCIE;SSCI | HEALTH CARE SCIENCES & SERVICES;HEALTH POLICY & SERVICES | 2022 | 2.8 | 48.9 | 0.11 | 2025-06-25 | 1 | 1 | dental unit chair; satisfaction factor; design; dentist; survey | HAND | Dental unit chair; Dentist; Design; Satisfaction factor; Survey | English | 2022 | 2022-03 | 10.3390/healthcare10030437 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | The First Step to Initiate Pediatric Palliative Care: Identify Patient Needs and Cooperation of Medical Staff | Few Korean hospitals had experience in pediatric palliative care. Since the beginning of the national palliative care project, interest in pediatric palliative care has gradually increased, but the establishment of professional palliative care is still inadequate due to a lack of indicators. This study aimed to find considerations in the process of initiating palliative care services. The general and clinical characteristics of 181 patients aged less than 24 years who were registered at the pediatric palliative care center from January 2019 to August 2021 were evaluated. Life-limiting condition group 1 had the largest number of patients. The primary need for palliative care was psychological and emotional support, followed by information sharing and help in communication with the medical staff in decision-making processes. Seventy-two patients were technologically dependent, with one to four technical supports for each patient. The registration of patients with cancer increased with time, and the time from disease diagnosis to consultation for pediatric palliative care service was significantly reduced. In conclusion, before starting pediatric palliative care, it is necessary to understand the needs of patients and their families and to cooperate with medical staff. | Bae, Su Hyun; Kim, Yeo Hyang | Kyungpook Natl Univ, Pediat Palliat Care Ctr, Childrens Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ, Dept Social Welf, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu 41566, South Korea | 57419144600; 57032023800 | b_suhyun@naver.com;kimyhmd@knu.ac.kr; | HEALTHCARE | HEALTHCARE-BASEL | 2227-9032 | 10 | 1 | SCIE;SSCI | HEALTH CARE SCIENCES & SERVICES;HEALTH POLICY & SERVICES | 2022 | 2.8 | 48.9 | 0.34 | 2025-06-25 | 4 | 3 | palliative care; children; life-limiting condition | OF-LIFE; CHILDREN; AVAILABILITY; COMPLEXITY | Children; Life-limiting condition; Palliative care | English | 2022 | 2022-01 | 10.3390/healthcare10010127 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Prognostic Value of Mesorectal Lymph Node Micrometastases in ypN0 Rectal Cancer After Chemoradiation | Introduction: More than 25% of patients with node-negative colorectal cancer experience a recurrent disease even after curative surgery. This suggests the existence and oncologic influence of micrometastasis in regional lymph nodes or in distant organs. The objective of this study was to identify mesorectal lymph node micrometastases using an immunohistochemical analysis and to determine its prognostic value in node-negative rectal cancer after neoadjuvant chemoradiation. Materials and Methods: A total of 91 patients who received preoperative chemoradiation and radical resection for rectal cancer were included. Based on conventional hematoxylin and eosin staining, all patients had a node-negative disease. Mesorectal lymph nodes from resected specimens were re-evaluated to detect micrometastases by immunohistochemistry using anticytokeratin antibody AE1/AE3. The clinicopathologic data were collected from a prospectively maintained database of colorectal cancer patients and analyzed retrospectively. Results: Micrometastases of mesorectal lymph nodes were detected in nine patients (9.9%). The three-year overall survival was similar regardless of micrometastasis (88.9% in the positive group versus 90.7% in the negative group, P = 0.681); however, the three-year disease-free survival was significantly poorer in the patients with micrometastases (40.0% versus 84.2%, P = 0.001). In the multivariate analysis, the advanced pT category (ypT3/T4 versus ypT0: hazard ratio [HR] 10.477, 95% confidence interval [CI] 1.102-99.594, P = 0.041) and micrometastases in mesorectal lymph nodes (HR 5.655, 95% CI 1.837-17.409, P = 0.003) were independent prognostic factors for disease-free survival. Conclusions: In node-negative rectal cancer after preoperative chemoradiation, immunohistochemically detected micrometastases of mesorectal lymph nodes were significantly correlated with poor disease-free survival. (c) 2022 Published by Elsevier Inc. | Kang, Byung Mo; Park, Jun-Seok; Kim, Hye Jin; Park, Soo Yeon; Yoon, Ghilsuk; Choi, Gyu-Seog | Hallym Univ, Chuncheon Sacred Heart Hosp, Dept Surg, Coll Med, Chunchon, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Surg, 807 Hogukno, Daegu 702210, South Korea | Park, Joonhong/AAZ-9885-2020; Kim, Hye/W-1059-2019 | 35292222200; 35226761100; 57204567554; 40561578300; 57204691355; 8058759100 | kyuschoi@knu.ac.kr; | JOURNAL OF SURGICAL RESEARCH | J SURG RES | 0022-4804 | 1095-8673 | 276 | SCIE | SURGERY | 2022 | 2.2 | 49.1 | 0.62 | 2025-06-25 | 3 | 3 | Immunohistochemistry; Lymph nodes; Micrometastases; Rectal cancer; Survival | NEGATIVE COLORECTAL-CANCER; PREOPERATIVE RADIOTHERAPY; CARCINOMA; IDENTIFICATION; FLUOROURACIL | Immunohistochemistry; Lymph nodes; Micrometastases; Rectal cancer; Survival | Humans; Lymph Nodes; Lymphatic Metastasis; Neoplasm Micrometastasis; Neoplasm Staging; Prognosis; Rectal Neoplasms; Retrospective Studies; cytokeratin AE1; cytokeratin AE3; cytokine antibody; fluorodeoxyglucose f 18; fluorouracil; folinic acid; oxaliplatin; adult; advanced cancer; aged; Article; cancer combination chemotherapy; cancer free survival; cancer patient; cancer prognosis; cancer surgery; cancer survival; continuous infusion; female; histopathology; human; human tissue; immunohistochemistry; lymph node metastasis; major clinical study; male; micrometastasis; multimodality cancer therapy; neoadjuvant chemoradiotherapy; overall survival; preoperative treatment; prospective study; radical resection; rectum cancer; retrospective study; cancer staging; lymph node; lymph node metastasis; micrometastasis; pathology; prognosis; rectum tumor | English | 2022 | 2022-08 | 10.1016/j.jss.2022.02.040 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Meeting Abstract | Changes in Socio-economic Status after Stroke: The Prospective Cohort Study | Son, Minam; Shin, Seyoung; Chang, Won Hyuk; Sohn, Min Kyun; Lee, Jongmin; Kim, Deog Young; Shin, Yong-Il; Oh, Gyung-Jae; Lee, Yang-Soo; Joo, Min Cheol; Lee, So Young; Song, Min-Keun; Han, Junhee; Ahn, Jeonghoon; Kim, Yun-Hee | Sungkyunkwan Univ, Samsung Med Ctr, Dept Phys & Rehabil Med,Sch Med, Ctr Prevent & Rehabil,Heart Vasc Stroke Inst, Seoul, South Korea; Chungnam Natl Univ, Dept Rehabil Med, Coll Med, Daejeon, South Korea; Konkuk Univ, Sch Med, Dept Rehabil Med, Seoul, South Korea; Yonsei Univ, Coll Med, Dept & Res Inst Rehabil Med, Seoul, South Korea; Pusan Natl Univ, Yangsan Hosp, Sch Med, Dept Rehabil Med, Pusan, South Korea; Wonkwang Univ, Sch Med, Dept Prevent Med, Iksan, South Korea; Kyungpook Natl Univ, Sch Med, Kyungpook Natl Univ Hosp, Dept Rehabil Med, Daegu, South Korea; Wonkwang Univ, Sch Med, Dept Rehabil Med, Iksan, South Korea; Jeju Natl Univ, Sch Med, Jeju Natl Univ Hosp, Dept Rehabil Med, Jeju, South Korea; Chonnam Natl Univ, Med Sch, Dept Phys & Rehabil Med, Gwangju, South Korea; Hallym Univ, Dept Stat, Chunchon, South Korea; Ewha Womans Univ, Dept Hlth Convergence, Seoul, South Korea; Sungkyunkwan Univ, Dept Digital Healthcare, Dept Hlth Sci & Technol, Dept Med Device Management & Res,SAIHST, Seoul, South Korea | Ahn, Jeonghoon/CAA-1956-2022; kim, deog young/Q-8498-2019; Lee, Jongmin/Q-4909-2019; Kim, Yun-Hee/GVS-6426-2022 | CEREBROVASCULAR DISEASES | CEREBROVASC DIS | 1015-9770 | 1421-9786 | 51 | SUPPL 1 | SCIE | CLINICAL NEUROLOGY;PERIPHERAL VASCULAR DISEASE | 2022 | 2.9 | 49.3 | 0 | English | 2022 | 2022-11 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Article | Changes in Stroke Patients' Health-Seeking Behavior by COVID-19 Epidemic Regions: Data from the Korean Stroke Registry | Introduction: The coronavirus disease 2019 (COVID-19) pandemic has led to changes in stroke patients' healthcare use. This study evaluated changes in Korean stroke patients' health-seeking behaviors and stroke care services using data from the Korean Stroke Registry (KSR). Methods: We reviewed data from patients with acute stroke and transient ischemic attack (TIA) during 2019 (before COVID-19 period) and 2020 (COVID-19 period). Outcomes included patient characteristics, time from stroke onset to hospital arrival, and in-hospital stroke pathways. Subgroup analyses were performed for an epidemic region (Daegu city and Gyeongsangbuk-do region, the D-G region). Results: The study included 1,792 patients from the pre-COVID-19 period and 1,555 patients from the COVID-19 period who visited hospitals that contribute to the KSR. During the COVID-19 period, the D-G region had two-thirds the number of cases (vs. the pre-CO-VID-19 period) and a significant decrease in the proportion of patients with TIA (9.97%-2.91%). Unlike other regions, the median onset-to-door time increased significantly in the D-G region (361 min vs. 526.5 min, p = 0.016), and longer onset-to-door times were common for patients with mild symptoms and who were in their 60s or 70s. The number of patients who underwent intravenous thrombolysis also decreased during the COVID-19 period, although the treatment times were not significantly different between the 2 periods. Discussion/Conclusion: Korean stroke patients in a CO-VID-19 epidemic region exhibited distinct changes in health-seeking behaviors. Appropriate triage system and public education regarding the importance of early treatment are needed during the COVID-19 pandemic. | Jeong, Han-Yeong; Lee, Eung-Joon; Kang, Min Kyoung; Nam, Ki-Woong; Bae, Jeonghoon; Jeon, Kipyoung; Jung, Keun-Hwa; Ko, Sang-Bae; Oh, Mi Sun; Lee, Ji Sung; Hwang, Jaechun; Jeong, Eunhwan; Lee, Jun; Do, Jin-Kuk; Sohn, Sung-Il; Kwon, Sun U.; Bae, Hee-Joon; Yoon, Byung-Woo; Park, Jong-Moo | Seoul Natl Univ Hosp, Ctr Emergency Med, Dept Neurol, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Neurol, Seoul, South Korea; Eulji Univ, Uijeongbu Eulji Med Ctr, Dept Neurol, Uijongbu, South Korea; Hallym Univ, Dept Neurol, Sacred Heart Hosp, Anyang, South Korea; Asan Med Ctr, Clin Res Ctr, Seoul, South Korea; Kyungpook Natl Univ, Dept Neurol, Chilgok Hosp, Daegu, South Korea; S Pohang Stroke & Spine Ctr, Dept Neurol, Pohang, South Korea; Yeungnam Univ, Dept Neurol, Med Ctr, Daegu, South Korea; Daegu Catholic Univ, Dept Neurol, Med Ctr, Daegu, South Korea; Keimyung Univ, Dept Neurol, Dongsan Med Ctr, Daegu, South Korea; Univ Ulsan, Dept Neurol, Asan Med Ctr, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Cerebrovasc Ctr, Dept Neurol,Coll Med, Seoul, South Korea | Yoon, Byung/J-5557-2012; Bae, Hee-Joon/J-5503-2012 | 57210509084; 57211337971; 57298821400; 57189377536; 57220197011; 56999928000; 7402479984; 7403326154; 24492191600; 57212925539; 54980345300; 57222358438; 55894819500; 8691392500; 36479287000; 7402624264; 7103223963; 13310144900; 8407334400 | thrombolysis@gmail.com; | CEREBROVASCULAR DISEASES | CEREBROVASC DIS | 1015-9770 | 1421-9786 | 51 | 2 | SCIE | CLINICAL NEUROLOGY;PERIPHERAL VASCULAR DISEASE | 2022 | 2.9 | 49.3 | 1.38 | 2025-06-25 | 11 | 12 | Stroke; Transient ischemic attack; Coronavirus disease 2019; Health-seeking behavior; Stroke registry | IMPACT | Coronavirus disease 2019; Health-seeking behavior; Stroke; Stroke registry; Transient ischemic attack | COVID-19; Humans; Pandemics; Patient Acceptance of Health Care; Registries; Republic of Korea; Retrospective Studies; Stroke; adult; aged; Article; atherosclerosis; atrial fibrillation; blood clot lysis; brain ischemia; cerebrovascular accident; coronary artery disease; coronavirus disease 2019; diabetes mellitus; education; emergency health service; emergency ward; epidemic; female; follow up; health care utilization; human; hyperlipidemia; hypertension; major clinical study; male; middle cerebral artery occlusion; National Institutes of Health Stroke Scale; pandemic; prevalence; prospective study; Rankin scale; retrospective study; risk factor; scoring system; stroke patient; transient ischemic attack; cerebrovascular accident; patient attitude; register; South Korea | English | 2022 | 2022-03 | 10.1159/000519093 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Meeting Abstract | Prediction of Functional Ambulation in Subacute Stroke Patients: The KOSCO Study | Cho, Doona; Kim, Jisu; Shin, Seyoung; Chang, Won Hyuk; Kim, Deog Young; Lee, Jongmin; Sohn, Min Kyun; Song, Min-Keun; Shin, Yong-il; Lee, Yang-Soo; Joo, Min Cheol; Lee, So Young; Han, Junhee; Ahn, Jeonghoon; Oh, Gyung-Jae; Kim, Yun-Hee | Sungkyunkwan Univ, Sch Med, Samsung Med Ctr,Dept Phys & Rehabil Med, Ctr Prevent & Rehabil,Heart Vasc Stroke Inst, Seoul, South Korea; Yonsei Univ, Coll Med, Dept & Res Inst Rehabil Med, Seoul, South Korea; Konkuk Univ, Sch Med, Dept Rehabil Med, Seoul, South Korea; Chungnam Natl Univ, Coll Med, Dept Rehabil Med, Daejeon, South Korea; Chonnam Natl Univ, Med Sch, Dept Phys & Rehabil Med, Gwangju, South Korea; Pusan Natl Univ, Yangsan Hospita, Sch Med, Dept Rehabil Med, Pusan, South Korea; Kyungpook Natl Univ Hosp, Sch Med, Dept Rehabil Med, Daegu, South Korea; Wonkwang Univ, Sch Med, Dept Rehabil Med, Iksan, South Korea; Jeju Natl Univ, Sch Med, Jeju Natl Univ Hosp, Dept Rehabil Med, Jeju, South Korea; Hallym Univ, Dept Stat, Chunchon, South Korea; Ewha Womans Univ, Dept Hlth Convergence, Seoul, South Korea; Wonkwang Univ, Sch Med, Dept Prevent Med, Iksan, South Korea; Sungkyunkwan Univ, Dept Hlth Sci & Technol, Dept Digital Hlth, Dept Med Device Management & Res,SAIHST, Seoul, South Korea | Kim, Yun-Hee/GVS-6426-2022; Lee, Jongmin/Q-4909-2019; kim, deog young/Q-8498-2019; Ahn, Jeonghoon/CAA-1956-2022 | CEREBROVASCULAR DISEASES | CEREBROVASC DIS | 1015-9770 | 1421-9786 | 51 | SUPPL 1 | SCIE | CLINICAL NEUROLOGY;PERIPHERAL VASCULAR DISEASE | 2022 | 2.9 | 49.3 | 0 | English | 2022 | 2022-11 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | ○ | Article | Synthetic propeptide design to enhance the secretion of heterologous proteins by Saccharomyces cerevisiae | Heterologous protein production in Saccharomyces cerevisiae is a useful and effective strategy with many advantages, including the secretion of proteins that require posttranslational processing. However, heterologous proteins in S. cerevisiae are often secreted at comparatively low levels. To improve the production of the heterologous protein, human granulocyte colony-stimulating factor (hG-CSF) in S. cerevisiae, a secretion-enhancing peptide cassette including an hIL-1 beta-derived propeptide, was added and used as a secretion enhancer to alleviate specific bottlenecks in the yeast secretory pathway. The effects of three key parameters-N-glycosylation, net negative charge balance, and glycine-rich flexible linker-were investigated in batch cultures of S. cerevisiae. Using a three-stage design involving screening, selection, and optimization, the production and secretion of hG-CSF by S. cerevisiae were significantly increased. The amount of extracellular mature hG-CSF produced by the optimized propeptide after the final stage increased by 190% compared to that of the original propeptide. Although hG-CSF was used as the model protein in the current study, this strategy applies to the enhanced production of other heterologous proteins, using S. cerevisiae as the host. | Cho, Ji Sung; Oh, Hye Ji; Jang, Young Eun; Kim, Hyun Jin; Kim, Areum; Song, Jong-Am; Lee, Eun Jung; Lee, Jeewon | Korea Univ, Coll Engn, Dept Chem & Biol Engn, Anam Ro 145, Seoul 136713, South Korea; Kyungpook Natl Univ, Sch Appl Chem Engn, Dept Chem Engn, Daehak Ro 80, Daegu 41566, South Korea | Lee, Seung Eun/ABG-1607-2021 | 57767120200; 57767852900; 57208085671; 57210863429; 57767853000; 18038701000; 57239965200; 7601480997 | eunjunglee@knu.ac.kr;leejw@korea.ac.kr; | MICROBIOLOGYOPEN | MICROBIOLOGYOPEN | 2045-8827 | 11 | 3 | SCIE | MICROBIOLOGY | 2022 | 3.4 | 49.3 | 1.61 | 2025-06-25 | 16 | 17 | human granulocyte colony-stimulating factor; Saccharomyces cerevisiae; secretion efficiency; synthetic propeptides | COLONY-STIMULATING FACTOR; ENDOGENOUS SIGNAL PEPTIDES; FACTOR HG-CSF; RECOMBINANT PROTEIN; N-GLYCOSYLATION; FEBRILE NEUTROPENIA; PRIMARY PROPHYLAXIS; COST-EFFECTIVENESS; HUMAN INTERLEUKIN-1-BETA; RECEIVING CHEMOTHERAPY | human granulocyte colony-stimulating factor; Saccharomyces cerevisiae; secretion efficiency; synthetic pro-peptides | Glycosylation; Humans; Mercury; Peptides; Saccharomyces cerevisiae; glycine; granulocyte colony stimulating factor; interleukin 1beta; mating hormone alpha factor; synthetic peptide; yeast killer factor; mercury; peptide; amino acid sequence; Article; controlled study; fungus culture; nonhuman; protein cleavage; protein expression; protein folding; protein glycosylation; protein secretion; protein transport; Saccharomyces cerevisiae; genetics; glycosylation; human; metabolism | English | 2022 | 2022-06 | 10.1002/mbo3.1300 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Anatomical View of Thoracodorsal Artery Variants Using Computed Tomography Angiography | Background: The latissimus dorsi (LD) muscle has a dominant pedicle with one thoracodorsal artery and receives sufficient blood by segmental circulation through several perforators. Thus, it is widely used in various reconstructive surgeries. We are reporting on the patterns of the thoracodorsal artery analyzed by chest computed tomography (CT) angiography. Methods: We analyzed the preoperative chest CT angiography results of 350 patients scheduled to undergo LD flap breast reconstruction following complete mastectomy for breast cancer between October 2011 and October 2020. Results: A total of 700 blood vessels were classified according to the Kyungpook National University Plastic Surgery-Thoracodorsal Artery (KNUPS-TDA) classification: 388 (185 right and 203 left), 126 (64 right and 62 left), 91 (49 right and 42 left), 57 (27 right and 30 left), and 38 (25 right and 13 left) vessels were classified as type I, type II, type III, type IV, and type V, respectively. Among 350 patients, 205 patients showed matching types for left and right vessels, whereas 145 patients showed mismatching types. For 205 patients with matching types, the distribution by type was 134, 30, 30, 7, and 4 patients with type I, type II, type III, type IV, and type V, respectively. For 145 patients with mismatching types, the distribution by different combinations was 48, 25, 28, 19, 2, 9, 7, 3, 1, and 3 patients with type I + type II, type I + type III, type I + type IV, type I + type V, type II + type III, type II + type IV, type II + type V, type III + type IV, type III + type V, and type IV + type V, respectively. Conclusion: While there is some diversity in the vascular anatomical structures of the LD flap, the dominant vessel can be found in a similar location in almost all cases and no flap had absence of a dominant vessel. Therefore, in surgical procedures using the thoracodorsal artery as the pedicle, preoperative radiological confirmation is not absolutely necessary; however, due to variants, performing the surgery with an understanding of this aspect should lead to good outcomes. © 2023. Thieme. All rights reserved. Thieme Medical Publishers, Inc. | Cho, Hyun Geun; Kang, Byeongju; Ryu, Jeong Yeop; Choi, Kang Young; Yang, Jung Dug; Chung, Ho Yun; Cho, Byung Chae; Lee, Jeeyeon; Park, Ho Yong; Lee, Joon Seok | Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, Daegu, South Korea | 57211205767; 57279815300; 56366349400; 57203745682; 55171704700; 7404007181; 55662871100; 37079213100; 56564377200; 56496041000 | leejspo@knu.ac.kr; | Journal of Reconstructive Microsurgery | J RECONSTR MICROSURG | 0743-684X | 1098-8947 | 39 | 8 | SCIE | SURGERY | 2022 | 2.1 | 49.5 | 0.41 | 2025-06-25 | 2 | latissimus dorsi flap; pedicle; thoracodorsal artery; vascular anatomy | Angiography; Arteries; Breast Neoplasms; Computed Tomography Angiography; Female; Humans; Mastectomy; Tomography, X-Ray Computed; iopamidol; pamiray 250; adult; aged; Article; breast cancer; breast reconstruction; cancer surgery; computed tomographic angiography; disease classification; female; human; latissimus dorsi flap; major clinical study; partial mastectomy; preoperative evaluation; simple mastectomy; thoracodorsal artery; thorax radiography; angiography; artery; breast tumor; diagnostic imaging; mastectomy; procedures; x-ray computed tomography | English | Final | 2022 | 10.1055/a-2040-1651 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Anti-skin-aging effects of tissue-cultured mountain-grown ginseng and quantitative HPLC/ELSD analysis of major ginsenosides | Mountain-grown ginseng has free radical scavenging activity and suppresses inflammation. We evaluated the anti-skinaging effects of tissue-cultured mountain-grown ginseng (TG) and its major ginsenosides. The effect of three extracts of TG and ginsenosides Rg1 (1), Rf (2), Rb1 (3), Re (4), and Rd (5) on the secretion of matrix metalloproteinase-1 (MMP-1) and collagen type I alpha 1 (COLIA1) was compared with that of tumor necrosis factor-alpha (TNF-alpha) stimulation of human dermal fibroblasts (HDFs), as determined via enzyme-linked immunosorbent assay. An analytical high-performance liquid chromatographic method with evaporative light-scattering detection (HPLC/ELSD) was developed for the simultaneous determination of the major ginsenosides in TG obtained via supercritical fluid CO2 or ethanol extraction. TG residues obtained via supercritical fluid CO2 extraction (TG1) and TG not subject to extraction (TG3) suppressed MMP-1 secretion in TNF-alpha-stimulated HDFs. Major ginsenoside content was higher in the TG1 than in residues extracted with ethanol (TG2) and TG3; ginsenoside Rg1 (1) content was the highest among all TG residues. Among them, ginsenosides Rg1 (1) and Re (4) suppressed MMP-1 in TNF-alpha-stimulated HDFs, whereas ginsenosides Rb1 (3) and Rd (5) increased COLIA1. In conclusion, TG and its active ginsenosides may have anti-skin-aging effects. Ginsenoside Rg1 (1) may also be beneficial in ameliorating skin damage. HPLC/ELSD can identify major ginsenosides and supercritical fluid CO2 extraction can be applied during health supplement or drug development. [GRAPHICS] . | Kim, Juree; Phung, Hung Manh; Lee, Sullim; Kim, Keun Tae; Son, Tae Kwon; Kang, Ki Sung; Lee, Sanghyun | Chung Ang Univ, Dept Plant Sci & Technol, Anseong 17546, South Korea; Gachon Univ, Dept Prevent Med, Seongnam 13120, South Korea; Gachon Univ, Dept Life Sci, Seongnam 13120, South Korea; Ximin Co Ltd, Daegu 42809, South Korea; Kyungpook Natl Univ, Dept Farm Management, Daegu 41566, South Korea; Apple Bio Co Ltd, Daegu 41566, South Korea; Chung Ang Univ, BET Res Inst, Anseong 17546, South Korea; Nat Prod Inst Sci & Technol, Anseong 17546, South Korea | ; Lee, Eun-Hye/KDN-5679-2024 | 57221873557; 57218609316; 57203754056; 57763668000; 24924047300; 8963300800; 56822660000 | slee@cau.ac.kr; | JOURNAL OF NATURAL MEDICINES | J NAT MED-TOKYO | 1340-3443 | 1861-0293 | 76 | 4 | SCIE | CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY | 2022 | 3.3 | 49.5 | 0.75 | 2025-06-25 | 5 | 6 | Anti-skin-aging; HPLC/ELSD; Supercritical fluid CO2 extraction; Tissue-cultured mountain-grown ginseng | PANAX-GINSENG; SAPONINS; RE; IDENTIFICATION; ANTIOXIDANT; CHEMISTRY; EXTRACT | Anti-skin-aging; HPLC/ELSD; Supercritical fluid CO<sub>2</sub> extraction; Tissue-cultured mountain-grown ginseng | Aging; Carbon Dioxide; Chromatography, High Pressure Liquid; Ethanol; Ginsenosides; Humans; Matrix Metalloproteinase 1; Panax; Tumor Necrosis Factor-alpha; collagen type I alpha 1 chain; ginseng extract; ginsenoside Rb 1; ginsenoside Rd; ginsenoside Re; ginsenoside Rf; ginsenoside Rg 1; interstitial collagenase; tumor necrosis factor; alcohol; carbon dioxide; ginsenoside; interstitial collagenase; tumor necrosis factor; analytic method; antiaging activity; Article; calibration; controlled study; drug screening; drug structure; enzyme inhibition; enzyme linked immunosorbent assay; enzyme release; evaporative light scattering detection; high performance liquid chromatography; human; human cell; light scattering; limit of detection; limit of quantitation; plant tissue culture; process development; skin defect; skin fibroblast; skin protection; validation process; aging; chemistry; high performance liquid chromatography; Panax; procedures | English | 2022 | 2022-09 | 10.1007/s11418-022-01633-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Inhibitory functions of cornuside on TGFBIp-mediated septic responses | Transforming growth factor p-induced protein (TGFBIp), as an extracellular matrix protein, is expressed TGF-p in some types of cells. Experimental sepsis is mediated by expressed and released TGFBIp in primary human umbilical vein endothelial cells (HUVECs). Cornuside (CNS) is a bisiridoid glucoside compound found in the fruit of Cornus officinalis SIEB. et ZUCC. Based on the known functions of CNS, such as the immunomodulatory and anti-inflammatory activities, we tested whether TGFBIp-mediated septic responses were suppressed by CNS in human endothelial cells and mice and investigated the underlying anti-septic mechanisms of CNS. Data showed that the secretion of TGFBIp by lipopolysaccharide (LPS) and severe septic responses by TGFBIp were effectively inhibited by CNS. And, TGFBIp-mediated sepsis lethality and pulmonary injury were reduced by CNS. Therefore, the suppression of TGFBIp-mediated septic responses by CNS suggested that CNS may be used as a potential therapeutic agent for several vascular inflammatory diseases, with the inhibition of the TGFBIp signaling pathway as the mechanism of action. [GRAPHICS] . | Ryu, Soo Ho; Kim, Chaeyeong; Kim, Nayeon; Lee, Wonhwa; Bae, Jong-Sup | Kyungpook Natl Univ, Coll Pharm, Res Inst Pharmaceut Sci, 80 Daehak Ro, Daegu 41566, South Korea; Sungkyunkwan Univ, Dept Chem, 2066 Seobu Ro, Suwon 16419, South Korea | Bae, Jong-Sup/AAU-9724-2020; Lee, Wonhwa/GLQ-6506-2022 | 57418127000; 57418696700; 57226179942; 50161632800; 16021543200 | wonhwalee@skku.edu;baejs@knu.ac.kr; | JOURNAL OF NATURAL MEDICINES | J NAT MED-TOKYO | 1340-3443 | 1861-0293 | 76 | 2 | SCIE | CHEMISTRY, MEDICINAL;PHARMACOLOGY & PHARMACY | 2022 | 3.3 | 49.5 | 0.62 | 2025-06-25 | 7 | 7 | Cornuside; TGFBIp; Sepsis; Severe inflammation; HUVEC | MATRIX PROTEIN BETA-IG-H3; SMOOTH-MUSCLE-CELLS; GROWTH; LIPOPOLYSACCHARIDE; ADHESION; SEPSIS; GENE; SUPPRESSES; EXPRESSION; MIGRATION | Cornuside; HUVEC; Sepsis; Severe inflammation; TGFBIp | Animals; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Pyrans; Transforming Growth Factor beta; 3 (4,5 dimethyl 2 thiazolyl) 2,5 diphenyltetrazolium bromide; antiinflammatory agent; cell adhesion molecule; cornuside; glucoside; immunoglobulin enhancer binding protein; messenger RNA; transforming growth factor beta; unclassified drug; cornuside; glucoside; pyran derivative; transforming growth factor beta; animal experiment; animal model; animal tissue; Article; cell viability; controlled study; enzyme activation; experimental sepsis; gene; human; human cell; in vitro study; in vivo study; lethality; leukocyte adherence; leukocyte migration; lung injury; male; mortality rate; mouse; nonhuman; protein expression; protein secretion; signal transduction; TGFBIp gene; umbilical vein endothelial cell; animal; C57BL mouse; metabolism | English | 2022 | 2022-03 | 10.1007/s11418-021-01601-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Regional and annual patterns in respiratory virus co-infection etiologies and antibiotic prescriptions for pediatric mycoplasma pneumoniae pneumonia | - OBJECTIVE: Mycoplasma pneu-moniae (M. pneumoniae) pneumonia is the sec-ond-most common cause of community -ac-quired pneumonia (CAP). This study aimed at investigating into the prevalence of macro-lide-resistant M. pneumoniae(MRMP) with respi-ratory virus co-infection and the antibiotic pre-scriptions in children with CAP in four provinces in Korea, and to assess the variations in the find-ings across regions and throughout the year. PATIENTS AND METHODS: This prospective study was conducted in 29 hospitals in Korea between July 2018 and June 2020. Among the enrolled 1,063 children with CAP, all 451 patients with M. pneumoniae underwent PCR assays of M. pneumoniae and respiratory viruses, and the presence of point mutations of residues 2063 and 2064 was evaluated. RESULTS: Gwangju-Honam (88.6%) showed the highest prevalence of MRMP pneumonia, while Daejeon-Chungcheong (71.3%) showed the lowest, although the differences in preva-lence were not significant (p=0.074). Co -infec-tion of M. pneumoniae pneumonia and respira-tory virus was observed in 206 patients (45.4%), and rhinovirus co-infection (101 children; 22.2%) was the most frequent. The prevalence of MRMP pneumonia with respiratory virus co-infection and the antibiotic prescriptions differed signifi-cantly among the four provinces (p 0.05) during the study period. CONCLUSIONS: The prevalence of M. pneu-moniae pneumonia with virus co-infection and antibiotic prescriptions could differ according to region, although the MRMP pneumonia rate showed no difference within Korea. | Sung, M.; Choi, H-J; Lee, M-H; Lee, J-Y; Kim, H-B; Ahn, Y-M; Kim, J-K; Kim, H-Y; Jung, S-S; Kim, M.; Kang, E-K; Yang, E-A; Lee, S-J; Park, Y.; Seo, J-H; Lee, E.; Yang, E-S; Park, K-S; Shin, M.; Chung, H-L; Jang, Y-Y; Choi, B-S; Kim, H.; Jung, J-A; Yu, S-T; Roh, E-J; Lee, E-S; Kim, J-T; Kim, B-S; Hwang, Y-H; Sol, I-S; Yang, H-J; Han, M-Y; Yew, H-Y; Cho, H-M; Kim, H-Y; Hn, Y-H; Im, D-H; Hwang, K.; Yoo, J.; Jung, S-O; Jeon, Y-H; Shim, J-Y; Chung, E-H | Soonchunhyang Univ, Dept Pediat, Gumi Hosp, Gumi, South Korea; Incheon Med Ctr, Dept Pediat, Incheon, South Korea; Hallym Univ, Dept Pediat, Chuncheon Sacred Heart Hosp, Chunchon, South Korea; Inje Univ, Dept Pediat, Sanggye Paik Hosp, Seoul, South Korea; Eulji Univ Hosp, Dept Pediat, Seoul, South Korea; Kangwon Natl Univ, Dept Pediat, Sch Med, Chunchon, South Korea; Pusan Natl Univ, Dept Pediat, Childrens Hosp, Yangsan, South Korea; Chungnam Natl Univ, Coll Med, Dept Pediat, Sejong Hosp, Sejong, South Korea; Dongguk Univ, Dept Pediat, Ilsan Hosp, Goyang, South Korea; Catholic Univ Korea, Coll Med, Dept Pediat, Seoul, South Korea; Eulji Univ, Sch Med, Dept Pediat, Daejeon, South Korea; Wonkwang Univ, Coll Med, Dept Pediat, Sanbon Hosp, Gunpo, South Korea; Dankook Univ, Dept Pediat, Coll Med, Cheonan, South Korea; Chonnam Natl Univ Med Sch, Chonnam Natl Univ Hosp, Dept Pediat, Gwangju, South Korea; Chosun Univ, Chosun Univ Hosp, Coll Med, Dept Pediat, Gwangju, South Korea; Presbyterian Med Ctr, Dept Pediat, Jeonju, South Korea; Soonchunhyang Univ, Coll Med, Dept Pediat, Bucheon Hosp, Bucheon, South Korea; Catholic Univ Daegu, Dept Pediat, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Dong A Univ, Dept Pediat, Coll Med, Busan, South Korea; Wonkwang Univ, Dept Pediat, Sch Med, Iksan, South Korea; Chungnam Natl Univ Hosp, Dept Pediat, Daejeon, South Korea; Catholic Univ Korea, Coll Med, Dept Pediat, Uijeongbu St Marys Hosp, Uijongbu, South Korea; Univ Ulsan, Gangneung Asan Hosp, Dept Pediat, Coll Med, Kangnung, South Korea; Busan St Marys Hosp, Dept Pediat, Busan, South Korea; Yonsei Univ, Severance Hosp, Dept Pediat, Coll Med, Seoul, South Korea; Soonchunhyang Univ, Seoul Hosp, Dept Pediat, Coll Med, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Pediat, Sch Med, Seongnam, South Korea; Kogel Hosp, Dept Pediat, Daejeon, South Korea; Kwangju Christian Hosp, Dept Pediat, Kwangju, South Korea; Pusan Natl Univ, Dept Pediat, Sch Med, Pusan, South Korea; Bundang Jesaeng Hosp, Dept Pediat, Seongnam, South Korea; Korea Dis Control & Prevent Agcy KDCA, Bur Infect Dis Diag Control, Divison Bacterial Dis, Sejong, South Korea; Hallym Univ, Dept Pediat, Dongtan Sacred Heart Hosp, Hwasung, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Pediat, Sch Med, Seoul, South Korea | Kim, Ju-Hyoung/N-1450-2019; Chung, Eunhee/AAX-6863-2020; kim, jeeyoung/AFK-5620-2022; Lee, Hoan/J-5616-2012; Lee, Min Young/GMX-1345-2022; Park, Eunju/AAC-5266-2021; Kim, Ha/AAC-5619-2019; Kim, Yongkang/AAC-7436-2020 | 57191221568; 58837142100; 56903238400; 57144743100; 57191720302; 56735321800; 7601384283; 59051653300; 57202732881; 56984405900; 55485131500; 55607660500; 57777804500; 57192714127; 22981399000; 58678989600; 36764244300; 56664911600; 8063810800; 7404006674; 59033110100; 56547873100; 59615136400; 7402897005; 56178493500; 57218885323; 57560987500; 35201365200; 35210645200; 57212011693; 56690279400; 15053595400; 16301607700; 57559889700; 57779499700; 57261054400; 57873438900; 57873439000; 8716633300; 57873805200; 55262166300; 26537543200; 7201856163; 35975693800 | jy7.shim@samsung.com;ehchung@cnu.ac.kr; | EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | EUR REV MED PHARMACO | 1128-3602 | 26 | 16 | SCIE | PHARMACOLOGY & PHARMACY | 2022 | 3.3 | 49.5 | 0.31 | 2025-06-25 | 3 | 2 | Key Mycoplasma pneumoniae; Macrolide-resistant My-coplasma pneumoniae; Macrolide-sensitive Mycoplas-ma pneumoniae; Children | COMMUNITY-ACQUIRED PNEUMONIA; REQUIRING HOSPITALIZATION; MACROLIDE RESISTANCE; CHILDREN; INFECTION | Children; Macrolide-resistant Mycoplasma pneumoniae; Macrolide-sensitive Mycoplasma pneumoniae; Mycoplasma pneumoniae | English | 2022 | 2022 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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