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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Isoliquiritigenin Reduces LPS-Induced Inflammation by Preventing Mitochondrial Fission in BV-2 Microglial Cells | Excessive microglial cell activation in the brain can lead to the production of various neurotoxic factors (e.g., pro-inflammatory cytokines, nitric oxide) which can, in turn, initiate neurodegenerative processes. Recent research has been reported that mitochondrial dynamics regulate the inflammatory response of lipopolysaccharide (LPS). Isoliquiritigenin (ISL) is a compound found in Glycyrrhizae radix with anti-inflammatory and antioxidant properties. In this study, we investigated the function of ISL on the LPS-induced pro-inflammatory response in BV-2 microglial cells. We showed that ISL reduced the LPS-induced increase in pro-inflammatory mediators (e.g., nitric oxide and pro-inflammatory cytokines) via the inhibition of ERK/p38/NF-kappa B activation and the generation of reactive oxygen species (ROS). Furthermore, ISL inhibited the excessive mitochondrial fission induced by LPS, regulating mitochondrial ROS generation and pro-inflammatory response by suppressing the calcium/calcineurin pathway to dephosphorylate Drp1 at the serine 637 residue. Interestingly, the ISL pretreatment reduced the number of apoptotic cells and levels of cleaved caspase3/PARP, compared to LPS-treated cells. Our findings suggested that ISL ameliorated the pro-inflammatory response of microglia by inhibiting dephosphorylation of Drp1 (Ser637)-dependent mitochondrial fission. This study provides the first evidence for the effects of ISL against LPS-induced inflammatory response related and its link to mitochondrial fission and the calcium/calcineurin pathway. Consequently, we also identified the protective effects of ISL against LPS-induced microglial apoptosis, highlighting the pharmacological role of ISL in microglial inflammation-mediated neurodegeneration. | Lee, Dong Gil; Nam, Bo Ra; Huh, Jae-Won; Lee, Dong-Seok | Kyungpook Natl Univ, Sch Life Sci, BK21 Plus KNU Creat BioRes Grp, Daegu, South Korea; Korea Res Inst Biosci & Biotechnol KRIBB, Cheongju, Cheongju, Chungcheongbuk, South Korea | 56824532400; 57219774809; 16645802900; 57210068061 | lee1@knu.ac.kr; | INFLAMMATION | INFLAMMATION | 0360-3997 | 1573-2576 | 44 | 2 | SCIE | CELL BIOLOGY;IMMUNOLOGY | 2021 | 4.657 | 49.7 | 1.21 | 2025-07-30 | 23 | 23 | microglia; lipopolysaccharide; isoliquiritigenin; mitochondrial fission; oxidative stress; calcium | NF-KAPPA-B; PROTEIN PHOSPHATASE; ACTIVATED MICROGLIA; ROS PRODUCTION; BRAIN; APOPTOSIS; MAPK; CALCINEURIN; DYNAMICS; LIPOPOLYSACCHARIDE | calcium; isoliquiritigenin; lipopolysaccharide; microglia; mitochondrial fission; oxidative stress | Animals; Anti-Inflammatory Agents; Apoptosis; Biomarkers; Calcineurin; Calcium; Cell Line; Chalcones; Cytokines; Flow Cytometry; Inflammation; Lipopolysaccharides; Mice; Microglia; Mitochondrial Dynamics; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; calcineurin; calcium; calpain; caspase 3; cyclooxygenase 2; dynamin related protein 1; I kappa B kinase; immunoglobulin enhancer binding protein; inducible nitric oxide synthase; interleukin 1beta; interleukin 6; isoliquiritigenin; messenger RNA; mitofusin 1; mitogen activated protein kinase; mitogen activated protein kinase p38; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; nitric oxide; protein Bax; protein bcl 2; reactive oxygen metabolite; stress activated protein kinase; transcription factor RelA; tumor necrosis factor; unclassified drug; antiinflammatory agent; biological marker; calcineurin; calcium; chalcone derivative; cytokine; isoliquiritigenin; lipopolysaccharide; lipopolysaccharide, E. coli O26-B6; animal cell; apoptosis; Article; BV-2 cell line; calcium cell level; controlled study; enzyme phosphorylation; flow cytometry; fluorescence intensity; in vitro study; lipopolysaccharide-induced inflammation; mitochondrial dynamics; mitochondrion; mouse; nonhuman; oxidative stress; protein dephosphorylation; real time polymerase chain reaction; Western blotting; animal; cell line; drug effect; inflammation; metabolism; microglia; pathophysiology; physiology; reverse transcription polymerase chain reaction | English | 2021 | 2021-04 | 10.1007/s10753-020-01370-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Prospective multicentre randomised clinical trial comparing survival rates, quality of life and nutritional status between advanced gastric cancer patients with different follow-up intensities: study protocol for the STOFOLUP trial | Introduction Patients who underwent curative gastrectorny for gastric cancer are regularly followed-up for the early detection of recurrence and postoperative symptom management. However, there is a lack of evidence with regard to proper surveillance intervals and diagnostic tools. This study aims to evaluate whether frequent surveillance tests have a survival benefit or improve the quality of life in patients who underwent curative resection for advanced gastric cancer. Methods and analysis The STOFOLUP trial is an investigator-initiated, parallel-assigned, multicentre randomised controlled trial involving 16 hospitals in the Republic of Korea. Patients (n=886) diagnosed with pathological stage II or III gastric adenocarcinoma will be randomised to either the 3-month or the 6-month group at a 1:1 ratio, stratified by trial site and tumour stage. Patients allocated to the 3-month group will undergo an abdominal CT scan every 3 months postoperatively and those allocated to the 6-month group will undergo CT every 6 months. The primary endpoint is 3-year overall survival and the secondary endpoints are quality of life, as assessed using KOrean QUality of life in Stomach cancer patients Study group-40, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and the stomach cancer-specific module (ST022), and nutritional outcomes. Other survival data including data concerning 3-year disease-free survival, recurrence-free survival, gastric cancer-specific survival and postrecurrence survival will also be estimated. The first patient was enrolled on July 2021 and active patient enrolment is currently underway. Ethics and dissemination This study has been approved by the Institutional Review Board of eight of the participating hospitals (NCC 2021-0085, KBSMC2021-01-059, SMC 2021-01-140, KC210EDE0082, 4-2021-0281, AJIRB-MED-INT-20-608, 2021-0515 and H-2102-093-1198). This study will be disseminated through peer-reviewed publications, national or international conferences. | Eom, Bang Wool; Koo, Dong-Hoe; An, Ji Yeong; Lee, Han Hong; Kim, Hyoung-Il; Hur, Hoon; Yoo, Moon-Won; Ryu, Min-Hee; Lee, Hyuk-Joon; Kim, Su Mi; Park, Ji-Ho; Min, Jae Seok; Seo, Kyung Won; Jeong, Sang-Ho; Jeong, Oh; Kwon, Oh Kyoung; Ryu, Seung Wan; Yoo, Chang Hak; Bae, Jae Moon; Ryu, Keun Won | Natl Canc Ctr, Ctr Gastr Canc, Goyang, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Sch Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Surg, Sch Med, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Surg, Seoul St Marys Hosp, Seoul, South Korea; Yonsei Univ, Severance Hosp, Dept Surg, Sch Med, Seoul, South Korea; Ajou Univ, Ajou Univ Hosp, Dept Surg, Sch Med, Suwon, South Korea; Univ Ulsan, Asan Med Ctr, Dept Surg, Coll Med, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Dept Oncol, Coll Med, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Surg, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Canc Res Inst, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Surg, Seongnam, South Korea; Gyeongsang Natl Univ, Gyeongsang Natl Univ Hosp, Dept Surg, Sch Med, Jinju, South Korea; Dongnam Inst Radiol & Med Sci, Dept Surg, Busan, South Korea; Kosin Univ, Gospel Hosp, Dept Surg, Coll Med, Busan, South Korea; Gyeongsang Natl Univ, Changwon Hosp, Dept Surg, Sch Med, Chang Won, South Korea; Chonnam Natl Univ, Hwasun Hosp, Dept Surg, Med Sch, Gwangju, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Surg, Sch Med, Daegu, South Korea; Keimyung Univ, Sch Med, Dept Surg, Dongsan Hosp, Daegu, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Surg, Sch Med, Seoul, South Korea | ; Eom, Bang Wool/K-4412-2016; Lee, Han/W-4924-2019; Hur, Hoon/AAI-1396-2019; Kim, Hyoungil/M-7288-2019; Eom, Bang/K-4412-2016; Min, Jae-Seok/ABG-5529-2022; Koo, Dong-Hoe/K-7561-2019 | 22984747200; 44261177000; 7202509644; 25723439600; 54402992800; 35319985500; 23020267900; 7101754860; 7501481303; 55694196400; 57202928322; 37031730000; 55436089700; 56949615000; 26428191900; 26536109900; 55420795900; 7201746340; 57199910551; 55667555300 | docryu@ncc.re.kr; | BMJ OPEN | BMJ OPEN | 2044-6055 | 11 | 12 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 3.007 | 49.7 | 0.8 | 2025-07-30 | 6 | 7 | CURATIVE RESECTION; ASYMPTOMATIC RECURRENCE; TOTAL GASTRECTOMY; VALIDATION; SURGERY; SURVEILLANCE; QLQ-C30 | gastrointestinal tumours; protocols & guidelines; surgery | Follow-Up Studies; Humans; Multicenter Studies as Topic; Nutritional Status; Prospective Studies; Quality of Life; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; albumin; cyanocobalamin; hemoglobin; iron; abdominal radiography; adjuvant chemotherapy; adult; advanced cancer; albumin blood level; Article; body composition; body mass; body weight change; cancer localization; cancer recurrence; cancer specific survival; cancer staging; cancer surgery; cancer survival; clinical trial protocol; controlled study; disease free survival; European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30; follow up; gastrectomy; hemoglobin blood level; human; information processing; iron binding capacity; iron blood level; metastasis; multicenter study; nutritional status; overall survival; parallel design; patient monitoring; postoperative care; prospective study; quality of life; randomization; randomized controlled trial; recurrence free survival; sample size; stomach adenocarcinoma; stomach surgery; surgical margin; survival rate; survival time; thorax radiography; time factor; vitamin blood level; x-ray computed tomography; multicenter study (topic); nutritional status; pathology; quality of life; randomized controlled trial (topic); stomach tumor | English | 2021 | 2021-12 | 10.1136/bmjopen-2021-056187 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Color Digital Holography Based on Generalized Phase-Shifting Algorithm with Monitoring Phase-Shift | Color digital holography (DH) has been researched in various fields such as the holographic camera and holographic microscope because it acquires a realistic color object wave by measuring both amplitude and phase. Among the methods for color DH, the phase-shifting DH has an advantage of obtaining a signal wave of objects without the autocorrelation and conjugate noises. However, this method usually requires many interferograms to obtain signals for all wavelengths. In addition, the phase-shift algorithm is sensitive to the phase-shift error caused by the instability or hysteresis of the phase shifter. In this paper, we propose a new method of color phase-shifting digital holography with monitoring the phase-shift. The color interferograms are recorded by using a focal plane array (FPA) with a Bayer color filter. In order to obtain the color signal wave from the interferograms with unexpected phase-shift values, we devise a generalized phase-shifting DH algorithm. The proposed method enables the robust measurement in the interferograms. Experimentally, we demonstrate the proposed algorithm to reconstruct the object image with negligibly small conjugate noises. | Jung, Minwoo; Jeon, Hosung; Lim, Sungjin; Hahn, Joonku | Kyungpook Natl Univ, Sch Elect & Elect Engn, 80 Daehak Ro, Daegu 41566, South Korea | 57216159562; 56663784700; 56706721300; 10142501600 | apvmf12@knu.ac.kr;jhs0485@office.knu.ac.kr;dlatjdwls0326@knu.ac.kr;jhahn@knu.ac.kr; | PHOTONICS | PHOTONICS-BASEL | 2304-6732 | 8 | 7 | SCIE | OPTICS | 2021 | 2.536 | 50.0 | 0.38 | 2025-07-30 | 5 | 4 | color holography; digital holography; phase-shift; phase measurement | INTERFEROMETRY; RECONSTRUCTION; RECOGNITION | Color holography; Digital holography; Phase measurement; Phase-shift | English | 2021 | 2021-07 | 10.3390/photonics8070241 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Effect of Reaction Product of Epichlorohydrin and Imidazole on the Electrodeposition Behavior of Zn-Ni Alloy from Alkaline Zincate Solution | A Zn-Ni alloy was electrodeposited on a Cu electrode at a current density of 10-5 000 A.m(-2), a charge of 5 x 10(4) C.m(-2), and temperature of 293 K in an unagitated zincate solution containing the reaction product of epichlorohydrin and imidazole (EI polymer) as a brightener. The effect of the EI polymer on the deposition behavior of the Zn-Ni alloy was investigated. The transition current densities at which the deposition behavior shifted from the normal type to anomalous were 50-100 A.m(-2) and 10-20 A.m(-2) in the EI polymer-free solution and polymer containing solutions, respectively, indicating that the EI polymer decreased the transition current density. The transition current density corresponded to the current density at which the potential of the total polarization curve significantly shifted from the more noble region than the equilibrium potential of Zn to the less noble region. The decrease in transition current density with EI polymer was attributed to the suppression of hydrogen evolution. In addition, the current efficiency for alloy deposition in the high-current-density region decreased due to the suppression of both Zn and Ni depositions. The Ni content of deposited films decreased with EI polymer, indicating that Ni deposition was more suppressed with the EI polymer addition than Zn deposition. With increasing current density, the crystals of the films deposited from the EI polymer-containing solution smoothened and showed significant brightness. The oxidation reaction of the films deposited from the EI polymer-containing solution was suppressed, thus causing the corrosion potential to shift to a noble direction. | Bae, Sung Hwa; Oue, Satoshi; Son, Injoon; Nakano, Hiroaki | Kyushu Univ, Grad Sch Engn, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan; Kyushu Univ, Fac Engn, Nishi Ku, 744 Motooka, Fukuoka 8190395, Japan; Kyungpook Natl Univ, Dept Mat Sci & Met, 80 Daehak Ro, Daegu 41566, South Korea | 57210171283; 6602167690; 9942975800; 35399160700 | nakano@zaiko.kyushu-u.ac.jp; | ISIJ INTERNATIONAL | ISIJ INT | 0915-1559 | 1347-5460 | 61 | 8 | SCIE | METALLURGY & METALLURGICAL ENGINEERING | 2021 | 1.864 | 50.0 | 0.95 | 2025-07-30 | 12 | 12 | zincate; zinc-nickel alloy; electrodeposition; brightener; anomalous codeposition; polarization curve; current density; transition current; current efficiency; corrosion potential | POLYETHYLENE-GLYCOL; CURRENT DENSITY; STEEL; DEPOSITION; MORPHOLOGY; MECHANISM; COATINGS; SULFATE; APPEARANCE; BATH | Anomalous codeposition; Brightener; Corrosion potential; Current density; Current efficiency; Electrodeposition; Polarization curve; Transition current; Zinc-nickel alloy; Zincate | Aromatic compounds; Corrosion; Current density; Electrodeposition; Electrodes; Nickel alloys; Polymer films; Reaction products; Corrosion potentials; Deposition behavior; Electro-deposition behaviors; Equilibrium potentials; High current densities; Oxidation reactions; Polarization curves; Transition currents; Chlorine containing polymers | English | 2021 | 2021 | 10.2355/isijinternational.isijint-2021-080 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | In Vivo Rodent Cervicothoracic Vasculature Imaging Using Photoacoustic Computed Tomography | Mice and rats are rodent specimens commonly used in multidisciplinary research. Specifically, vasculature imaging of rodents has been widely performed in preclinical studies using various techniques, such as computed tomography, magnetic resonance imaging, and ultrasound imaging. Photoacoustic CT (PACT) is a noninvasive, nonionizing optical imaging technique derived from photoacoustic tomography and benefits from using intrinsic endogenous contrast agents to produce three-dimensional volumetric data from images. In this study, a commercial PACT device was employed to assess the cervicothoracic vasculature of mouse and rat specimens, which has rarely been examined using PACT, under two conditions with depilation and skin incision. Various blood vessels, including the common carotid artery, internal/external jugular veins, cranial vena cava, internal thoracic vein, and mammary, were identified in the acquired PACT images. The difference between the depilated and skin-incised specimens also revealed the presence of branches from certain blood vessels and specific anatomical features such as the manubrium of the sternum. This study presents detailed PACT images observing the cervicothoracic vasculature of rodent specimens and is expected to be used as a reference for various preclinical experiments on mice and rats. | Lee, Junsoo; Cho, Hoseong; Park, Sungjo; Lee, Jaeyul; Seong, Daewoon; Wijesinghe, Ruchire Eranga; Han, Sangyeob; Kim, Shinheon; Jeon, Mansik; Kim, Jeehyun | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Pohang Univ Sci & Technol, Pohang Innotown Ctr, Pohang 37673, South Korea; Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA; Univ Sri Jayewardenepura, Fac Technol, Dept Mat & Mech Technol, Pitipana 10200, Homagama, Sri Lanka; Kyungpook Natl Univ, Inst Biomed Engn, Daegu 41566, South Korea | Wijesinghe, Ruchire/K-3797-2016; Lee, Jung Bok/HHZ-3200-2022; Lee, Junsoo/IUO-9627-2023; Han, Sangyeob/W-3206-2018 | 57209986073; 57209416599; 7501826338; 57188689420; 57212512353; 56018152300; 57193695305; 57226603736; 24171094000; 7601373350 | jslee5399@knu.ac.kr;ghtjd419@knu.ac.kr;psj2686@postech.ac.kr;jaeyul21@g.ucla.edu;smc7095@knu.ac.kr;erangawijesinghe@sjp.ac.lk;syhan850224@knu.ac.kr;shawnkim@knu.ac.kr;msjeon@knu.ac.kr;jeehk@knu.ac.kr; | PHOTONICS | PHOTONICS-BASEL | 2304-6732 | 8 | 8 | SCIE | OPTICS | 2021 | 2.536 | 50.0 | 0.19 | 2025-07-30 | 1 | 2 | rodent; small animal; vascular imaging; angiography; photoacoustic imaging; photoacoustic computed tomography; cervicothoracic vasculature | MOUSE; BEHAVIOR | Angiography; Cervicothoracic vasculature; Photoacoustic computed tomography; Photoacoustic imaging; Rodent; Small animal; Vascular imaging | English | 2021 | 2021-08 | 10.3390/photonics8080312 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Iron nitride based magnetic powder synthesized by mechanical alloying of Fe-based glassy powders and solid nitrogen compounds | Iron nitrides composed of abundant and inexpensive Fe and N compounds such as alpha''-Fe16N2 and gamma'-Fe4N are in the spotlight as potential magnetic materials for the next generation of electric vehicles. Extensive applications of iron nitrides, however, have not been reported since their mass production is yet to be established. Due to the low solubility of nitrogen in liquid iron, the production of iron nitrides through conventional steelmaking processes is difficult. Moreover, alpha''-Fe16N2 with a high saturation magnetization is known to be metastable and can form below 200 degrees C where diffusional phase transformations are slow. In this study, we propose a nonequilibrium process that can enhance the kinetics for iron nitride formation at low temperatures. Thermodynamically metastable Fe-based glassy alloy with a relatively open atomic packing structure was used as the starting material. Synthesis of iron nitrides during the mechanical alloying of Fe-based amorphous powders and solid nitrogen compounds was systematically studied to understand the mechanism of solid state nitriding reactions. In addition, thermal and magnetic properties were studied to provide a basis for practical applications of iron nitrides as rare-earth free magnetic materials. | Kim, Jinyoung; Hwang, Jiyong; Yi, Seonghoon | Kyungpook Natl Univ, Mat Sci & Met Engn, Daegu 41566, South Korea | ; Yi, Seonghoon/HGC-6912-2022 | 58384365900; 57190225749; 14008383000 | yish@knu.ac.kr; | JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | J MAGN MAGN MATER | 0304-8853 | 1873-4766 | 539 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;PHYSICS, CONDENSED MATTER | 2021 | 3.097 | 50.0 | 0.56 | 2025-07-30 | 9 | 10 | Fe-based metallic glass powder; Mechanical alloying; Iron nitride; Magnetic property | SATURATION MAGNETIZATION; FILMS; ALPHA''-FE16N2; FE16N2; MARTENSITE; MOMENT | Fe-based metallic glass powder 1; Iron nitride 3; Magnetic property 4; Mechanical alloying 2 | Aluminum nitride; Glass; Magnetic materials; Magnetic properties; Nitrides; Rare earths; Saturation magnetization; Solid state reactions; Fe-based; Fe-based metallic glass powder 1; Iron nitride 3; Iron nitrides; Magnetic powders; Magnetic property 4; Mechanical; Mechanical alloying 2; Metastables; Solid nitrogen; Iron compounds | English | 2021 | 2021-12-01 | 10.1016/j.jmmm.2021.168329 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Korean clinical practice guideline for pancreatic cancer 2021: A summary of evidence-based, multi-disciplinary diagnostic and therapeutic approaches | Pancreatic cancer is the eighth most common cancer and the fifth most common cause of cancer-related death in Korea. To enable standardization of management and facilitate improvements in outcome, a total of 53 multi-disciplinary experts in gastroenterology, surgery, medical oncology, radiation oncology, radiology, nuclear medicine, and pathology in Korea developed new recommendations that integrate the most up-to-date, evidence-based research findings and expert opinions. Recommendations were made on imaging diagnosis, endoscopic management, surgery, radiotherapy, palliative chemotherapy, and specific management procedures, including neoadjuvant treatment or adjuvant treatment for patients with resectable, borderline resectable, and locally advanced unresectable pancreatic cancer. This is the English version of the Korean clinical practice guideline for pancreatic cancer 2021. This guideline includes 20 clinical questions and 32 statements. This guideline represents the most standard guideline for the diagnosis and treatment of patients with pancreatic ductal adenocarcinoma in adults at this time in Korea. The authors believe that this guideline will provide useful and informative advice. (c) 2021 IAP and EPC. Published by Elsevier B.V. All rights reserved. | Kim, Sun-Whe; Yu, Jeong Il; Lee, Ik Jae; Park, Mi-Suk; Hwang, Shin Hye; Yang, Hyun Kyung; Jeong, Woo Kyoung; Lee, Seung Soo; Kim, Jung Hoon; Choi, Joon Young; O, Joo-Hyun; Lee, Jeong Won; Lee, Sang-Woo; Hong, Seung-Mo; Jang, Kee-Taek; Lee, Kyoung-Bun; Kim, Haeryoung; Choi, Mi Young; Lee, Woo Jin | Natl Canc Ctr, Goyang, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Ulsan, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Seoul, South Korea; Yonsei Univ, Coll Med, Gangnam Severance Hosp, Seoul, South Korea; Yonsei Univ, Coll Med, Severance Hosp, Seoul, South Korea; Natl Hlth Insurance Serv Ilsan Hosp, Goyang, South Korea; Seoul Natl Univ, Coll Med, Seoul Natl Univ Hosp, Seoul, South Korea; Catholic Univ, Coll Med, Seoul St Marys Hosp, Seoul, South Korea; Catholic Kwandong Univ, Coll Med, Int St Marys Hosp, Kangnung, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Daegu, South Korea; Natl Evidence Based Healthcare Collaborating Agcy, Seoul, South Korea | ; Lee, Kyoungbun/F-6358-2011; Yu, Jeong Il/MTC-0984-2025; Lee, Sang Mi/AAC-7045-2022; Kim, Yongkang/AAC-7436-2020; Choi, Joon/D-6140-2017; Lee, Woojin/AAZ-1735-2020; Jeong, Woo Kyoung/ABE-7025-2021; Lee, Sang/L-8626-2016 | 36062488800; 57205641466; 56607536600; 26028951400; 57202974895; 35310739500; 57203537385; 57278859200; 55532796800; 58838319500; 57206878084; 57225705236; 35227488700; 25951294300; 44261177000; 55801992400; 22954694200; 55295589700; 55740202300; 37117816900; 34968209400; 35211119200; 35210819100; 8933394000; 23397796100; 41562471000; 14819232800; 7402126748; 7402965187; 7801394373; 55446661100; 55897965000; 58761553100; 22635319800; 35212472500; 36786568600; 58669790400; 56397382400; 56121212600; 14012468500; 48061088800; 57964863500; 8941826200; 16023185400; 56675072800; 57196249819; 58628329900; 10140921200; 7501517217; 35307240200; 57129603200; 55619312784 | PANCREATOLOGY | PANCREATOLOGY | 1424-3903 | 1424-3911 | 21 | 7 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 3.977 | 50.0 | 0.71 | 2025-07-30 | 14 | 12 | Pancreatic cancer; Practice guideline; Surgery; Chemotherapy; Radiotherapy | EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY; MESENTERIC VEIN RESECTION; FORMING AUTOIMMUNE PANCREATITIS; CHEST COMPUTED-TOMOGRAPHY; NEOADJUVANT THERAPY; EXTENDED LYMPHADENECTOMY; DUCTAL ADENOCARCINOMA; OPEN PANCREATICODUODENECTOMY; STAGING LAPAROSCOPY; NAB-PACLITAXEL | Chemotherapy; Pancreatic cancer; Practice guideline; Radiotherapy; Surgery | Carcinoma, Pancreatic Ductal; Gastroenterology; Humans; Neoadjuvant Therapy; Pancreatic Neoplasms; antineoplastic agent; CA 19-9 antigen; fluorodeoxyglucose f 18; fluorouracil; folinic acid; gemcitabine; irinotecan; oxaliplatin; paclitaxel; programmed death 1 receptor; adjuvant chemotherapy; adjuvant radiotherapy; adjuvant therapy; advanced cancer; Article; Asia; biliary tract drainage; cancer combination chemotherapy; cancer palliative therapy; cancer recurrence; cancer staging; celiac artery; cytology; diagnostic imaging; diagnostic procedure; differential diagnosis; dissection; distal pancreatectomy; duodenum obstruction; endoscopic ultrasonography; endoscopic ultrasound guided fine needle biopsy; fine needle aspiration biopsy; fluoroscopy; hepatic portal vein; high risk patient; histology; human; inoperable cancer; interdisciplinary research; laparoscopy; laparotomy; liver metastasis; lung metastasis; lymph node dissection; metastasis; minimally invasive surgery; neoadjuvant chemoradiotherapy; neoadjuvant chemotherapy; neoadjuvant therapy; nerve plexus; nuclear magnetic resonance; nuclear magnetic resonance imaging; obstructive jaundice; palliative chemotherapy; pancreas cancer; pancreatic head cancer; pancreaticoduodenectomy; pancreatography; particle therapy; positron emission tomography-computed tomography; practice guideline; protein expression; radical resection; recurrent disease; stereotactic body radiation therapy; superior mesenteric artery; superior mesenteric vein; thorax radiography; transabdominal ultrasound; treatment planning; tumor regression; x-ray computed tomography; gastroenterology; pancreas carcinoma; pancreas tumor; practice guideline | English | 2021 | 2021-10 | 10.1016/j.pan.2021.05.004 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Malignant potential of small pancreatic neuroendocrine neoplasm and its risk factors: A multicenter nationwide study | Background: Pancreatic neuroendocrine neoplasms (PNENs) show heterogeneous biological behavior, and most small PNENs show indolent features. Consequently, selected cases can be considered for observation only, according to the National Comprehensive Cancer Network guideline, however, supporting clinical evidence is lacking. We investigated the clinical course of small PNENs and their risk factors for malignant potential. Methods: A total of 158 patients with small pathologically confirmed PNENs <= 2 cm in initial imaging were retrospectively enrolled from 14 institutions. The primary outcome was any metastasis or recurrence event during follow-up. Results: The median age was 57 years (range, 22-82 years), and 86 patients (54%) were female. The median tumor size at initial diagnosis was 13 mm (range, 7-20 mm). PNENs were pathologically confirmed by surgery in 137 patients and by EUS-guided fine needle aspiration biopsy (EUS-FNAB) in 21 patients. Eight patients underwent EUS-FNAB followed by surgical resection. The results of WHO grade were available in 150 patients, and revealed 123 grade 1, 25 grade 2, and 2 neuroendocrine carcinomas. A total of 145 patients (92%) underwent surgical resection, and three patients had regional lymph node metastasis. During the entire follow-up of median 45.6 months, 11 metastases or recurrences (7%) occurred. WHO grade 2 (HR 13.97, 95% CI 2.60-75.03, p = 0.002) was the only predictive factor for malignant potential in multivariable analysis. Conclusions: WHO grade is responsible for the malignant potential of small PNENs <= 2 cm. Thus, EUS-FNAB could be recommended in order to provide early treatment strategies of small PNENs. (C) 2020 Published by Elsevier B.V. on behalf of IAP and EPC.Y | Paik, Woo Hyun; Lee, Hee Seung; Lee, Kyong Joo; Jang, Sung Ill; Lee, Woo Jin; Hwang, Jin-Hyeok; Cho, Chang Min; Park, Chang-Hwan; Han, Jimin; Woo, Sang Myung; Jeong, Seok; Chon, Hyung Ku; Kim, Tae Nyeun; Lee, Jun Kyu; Han, Joung-Ho; Yoon, Jai Hoon; Kim, Yong-Tae; Cho, Jae Hee | Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Liver Res Inst, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Wonju Severance Christian Hosp, Dept Internal Med, Wonju, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Natl Canc Ctr, Ctr Liver & Pancreatobiliary Canc, Goyang, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Coll Med, Seongnam, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea; Daegu Catholic Univ, Div Gastroenterol, Dept Internal Med, Sch Med, Daegu, South Korea; Inha Univ, Dept Internal Med, Sch Med, Incheon, South Korea; Wonkwang Univ, Dept Internal Med, Coll Med, Iksan, South Korea; Yeungnam Univ, Dept Internal Med, Coll Med, Daegu, South Korea; Dongguk Univ, Dept Internal Med, Ilsan Hosp, Goyang, South Korea; Chungbuk Natl Univ, Chungbuk Natl Univ Hosp, Coll Med, Dept Internal Med, Cheongju, South Korea; Hanyang Univ, Seoul Hosp, Dept Internal Med, Coll Med, Seoul, South Korea | ; Kim, Yong Tae/CKE-7709-2022; Paik, Woo Hyun/B-9003-2016; Han, Jimin/AAC-5497-2022; Paik, Woo/B-9003-2016; Kim, Min/ACN-6827-2022; Cho, Jae Hee/AAL-8192-2020; Jeong, Seok/C-9987-2011; Chon, Hyung ku/AGO-1334-2022 | 35822559900; 56713997700; 35750090700; 43761242600; 55619312784; 35200778600; 57158287600; 57207441931; 8694531200; 14038271300; 56012707900; 57191108189; 8449938100; 57201264381; 56222314400; 7403587413; 56071859800; 56501033700 | yongtkim@snu.ac.kr;jhcho9328@yuhs.ac; | PANCREATOLOGY | PANCREATOLOGY | 1424-3903 | 1424-3911 | 21 | 1 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2021 | 3.977 | 50.0 | 1.1 | 2025-07-30 | 14 | 14 | Pancreatic neoplasm; Prognosis; Size; Recurrence; Metastasis | ENETS CONSENSUS GUIDELINES; FINE-NEEDLE-ASPIRATION; COMPUTED-TOMOGRAPHY; ENDOSCOPIC ULTRASONOGRAPHY; KI-67 INDEX; TUMORS; MANAGEMENT; DIAGNOSIS; RESECTION; FEATURES | Metastasis; Pancreatic neoplasm; Prognosis; Recurrence; Size | Adult; Aged; Aged, 80 and over; Biopsy, Fine-Needle; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lymphatic Metastasis; Male; Middle Aged; Neuroendocrine Tumors; Pancreatectomy; Pancreatic Neoplasms; Progression-Free Survival; Republic of Korea; Surveys and Questionnaires; Young Adult; CA 19-9 antigen; chromogranin A; cisplatin; contrast medium; everolimus; Ki 67 antigen; adult; aged; Article; cancer combination chemotherapy; cancer diagnosis; cancer grading; cancer surgery; cancer survival; chemoembolization; computer assisted tomography; distal pancreatectomy; distant metastasis; endoscopic ultrasound guided fine needle biopsy; event free survival; female; follow up; histopathology; human; human tissue; liver metastasis; lymph node metastasis; major clinical study; male; malignant transformation; metastasis; middle aged; neuroendocrine carcinoma; nuclear magnetic resonance; pancreas islet cell tumor; pancreaticoduodenectomy; preoperative evaluation; priority journal; recurrence free survival; recurrent disease; retrospective study; risk factor; segmentectomy; tumor volume; clinical trial; fine needle aspiration biopsy; Kaplan Meier method; lymph node metastasis; multicenter study; neuroendocrine tumor; pancreas tumor; pancreatectomy; pathology; questionnaire; South Korea; very elderly; young adult | English | 2021 | 2021-01 | 10.1016/j.pan.2020.11.016 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Morphology and surface characteristics of the anamorphic stage of powdery mildew Erysiphe australiana on crape myrtle leaves | The morphology and surface characteristics of the powdery mildew Erysiphe australiana growing on crape myrtle leaves were observed with field emission scanning electron microscopy. The powdery mildew infection caused distortion and withering of the leaves, and nearly all external parts such as flowers, petioles, and branches were covered by the whitish colonies. Hyphal proliferation was prevalent on the adaxial surface of the powdery mildew-infected leaves. Globose ascocarp initials with hyphal aggregations were frequently seen on the leaf surface. Collapsed conidia showed longitudinal striations or ridges on the surface and deep linear wrinkling. Foot-cells were straight and grew at right angles from the vegetative hyphae. The conidiophores had fragmented, cylindrical, non-chained conidia which were produced singly at the apex of the conidiophores. The germ tubes formed intercalary multi-lobed appressoria and the conidia produced filiform protrusions emerging from sub terminal positions. This study visualized previously unknown structures of E. australiana such as the ascocarp initials, filiform protrusions on conidia, and multi-lobed appressoria on germ tubes. These observations will facilitate the identification and taxonomy of this fungus and its allied species. | Kim, Ki Woo | Kyungpook Natl Univ, Sch Ecol & Environm Syst, Sangju 37224, South Korea; Kyungpook Natl Univ, Tree Diagnost Ctr, Sangju 37224, South Korea | Kim, Ki Woo/AAC-5623-2022 | 57201369889 | kiwoo@knu.ac.kr; | MICRON | MICRON | 0968-4328 | 1878-4291 | 143 | SCIE | MICROSCOPY | 2021 | 2.381 | 50.0 | 0.37 | 2025-07-30 | 8 | 7 | Appressoria; Ascocarp; Lagerstroemia indica | Appressoria; Ascocarp; Lagerstroemia indica | Field emission microscopes; Fungi; Scanning electron microscopy; Anamorphic; Field emission scanning electron microscopy; Germ tubes; Leaf surfaces; Powdery mildew; Surface characteristics; article; conidium; Erysiphe; foot; fruiting body; fungus hyphae; Lagerstroemia indica; leaf surface; nonhuman; powdery mildew; wrinkle; Morphology | English | 2021 | 2021-04 | 10.1016/j.micron.2021.103013 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Single- or double-membrane-bound vesicles and P, Ca, and Fe-containing granules in Xanthomonas citri cultured on a solid medium | The organelle-like structures of Xanthomonas citri, a bacterial pathogen that causes citrus canker, were investigated using an analytical transmission electron microscope. After high-pressure freezing, the bacteria were then freeze-substituted for imaging and element analysis. Miniscule electron-dense structures of varying shapes without a membrane enclosure were frequently observed near the cell poles in a 3-day culture. The bacteria formed cytoplasmic electron-dense spherical structures measuring approximately 50 nm in diameter. Furthermore, X. citri produced electron-dense or translucent ellipsoidal intracellular or extracellular granules. Singleor double-membrane-bound vesicles, including outer-inner membrane vesicles, were observed both inside and outside the cells. Most cells had been lysed in the 3-week X. citri culture, but they harbored one or two electron dense spherical structures. Contrast-inverted scanning transmission electron microscopy images revealed distinct white spherical structures within the cytoplasm of X. citri. Likewise, energy-dispersive X-ray spectrometry showed the spatial heterogeneity and co-localization of phosphorus, oxygen, calcium, and iron only in the cytoplasmic electron-dense spherical structures, thus corroborating the nature of polyphosphate granules. | Park, Junhyung; Je, A. Reum; Lee, Sang Gil; Jang, Jae Hyuck; Huh, Yang Hoon; Park, Jucheol; Kim, Ki Woo | Kyungpook Natl Univ, Dept Ecol & Environm Syst, Sangju 37224, South Korea; Korea Basic Sci Inst, Ctr Electron Microscopy Res, Daejeon 34133, South Korea; Gumi Elect & Informat Technol Res Inst, Test Anal Ctr, Gumi 39171, South Korea; Kyungpook Natl Univ, Tree Diagnost Ctr, Sangju 37224, South Korea | ; Lee, Sang/AAE-7003-2021; Kim, Ki Woo/AAC-5623-2022 | 57202928407; 56020294800; 57203597209; 36792809400; 7102963459; 8733446100; 57201369889 | hyh1127@kbsi.re.kr;kiwoo@knu.ac.kr; | MICRON | MICRON | 0968-4328 | 1878-4291 | 143 | SCIE | MICROSCOPY | 2021 | 2.381 | 50.0 | 0.06 | 2025-07-30 | 1 | 1 | Acidocalcisome; Membrane vesicle; Polyphosphate granule | Acidocalcisome; Membrane vesicle; Polyphosphate granule | Bacteria; Cell proliferation; Cytology; Granulation; High resolution transmission electron microscopy; Scanning electron microscopy; Spheres; Transmissions; Analytical transmission electron microscope; Bacterial pathogens; Dense structures; Energy dispersive X-ray spectrometry; High-pressure freezing; Scanning transmission electron microscopy; Spatial heterogeneity; Spherical structures; Electrons | English | 2021 | 2021-04 | 10.1016/j.micron.2021.103024 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Ultrastructure of phytoplasma-infected jujube leaves with witches' broom disease | The subcellular characteristics of phytoplasma-infected jujube (Ziziphus jujuba) leaves were investigated using transmission electron microscopy. Midrib fragments of witches' broom-diseased jujube leaves were collected from abnormally small leaves at an early stage of branch clustering. The diseased jujube leaves showed multi vesicular bodies (MVBs) with vesicles and tubules in the phloem parenchyma cells and sieve elements. The MVBs were connected to the plasma membrane appressed to the cell wall. There were increased callose collars at the pore-plasmodesma unit ends of the sieve elements in the diseased leaves than in control leaves. The proliferation of MVBs in the diseased jujube leaves could be associated with endoplasmic reticulum stress-dependent exosome release. The phytoplasma produced pleomorphic cells in sieve elements. Several types of putative extracellular structures were observed on the phytoplasma cells: (i) fimbriae-like threads, (ii) pili-like projections, (iii) flagella-like appendages, and (iv) tube-like structures. This study provides novel insights into intracellular obligate cell wall-less prokaryotes and host phloem structures. | Park, Junhyung; Kim, Hyo-Jeong; Huh, Yang Hoon; Kim, Ki Woo | Kyungpook Natl Univ, Dept Ecol & Environm Syst, Sangju 37224, South Korea; Korea Basic Sci Inst, Ctr Electron Microscopy Res, Cheongju 28119, South Korea; Kyungpook Natl Univ, Tree Diagnost Ctr, Sangju 37224, South Korea | Kim, Ki Woo/AAC-5623-2022 | 57202928407; 57261045600; 7102963459; 57201369889 | hyh1127@kbsi.re.kr;kiwoo@knu.ac.kr; | MICRON | MICRON | 0968-4328 | 1878-4291 | 148 | SCIE | MICROSCOPY | 2021 | 2.381 | 50.0 | 0.25 | 2025-07-30 | 4 | 4 | Exosome; Multivesicular bodies; Phytoplasma; Witches' broom disease; Ziziphus jujuba | COMBINED MICROSCOPY; VIRUS; CELLS | Exosome; Multivesicular bodies; Phytoplasma; Witches’ broom disease; Ziziphus jujuba | Cell membranes; High resolution transmission electron microscopy; Road construction; Sieves; Endoplasmic reticulum stress; Extracellular structure; In-control; Multivesicular bodies; Parenchyma cells; Phytoplasmas; Sub-cellular; Ziziphus jujuba; Cytology | English | 2021 | 2021-09 | 10.1016/j.micron.2021.103108 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Victimizing innovative employees: joint roles of in-role behavior and task interdependence | Purpose This study aims to examine how an employee's engagement in innovative behavior (IB) can lead to the experience of aggressive actions from other members of an organization and the joint roles of employee in-role performance and task interdependence in this relationship. Design/methodology/approach A field study conducted among a diverse sample of employees working in various industries provided converging evidence for the theorized predictions. The sample of 204 full-time employees is included in the analyses. Findings The results confirmed that innovative employees can be targets of victimization in an organization and employees' high in-role performance and high task interdependence jointly moderate the negative relationship between innovative performance and victimization. Research limitations/implications The current study should be evaluated in light of some limitations, such as single-source data and the use of cross-sectional data. Practical implications It is advised that innovative individuals should accomplish their required duties in highly task-interdependent contexts to avoid harmful responses from peers. Managers should be aware of the potential negative side of IB. The data involving various industries provide evidence for the generalizability of the research findings and conclusions. Originality/value This paper advances the understanding of the consequences of creative behavior by examining the unexplored aspect that innovative employees can become victims of peer mistreatments. It also expands the understanding of negative outcomes of engaging in creativity by concurrently examining moderating roles of in-role behavior and task interdependence. | Dadaboyev, Sherzodbek Murodilla Ugh; Baek, Yoonjung; Ahn, Scong Ik | Kyungpook Natl Univ, Sch Business Adm, Daegu, South Korea; Yeungnam Univ, Sch Business, Gyongsan, South Korea | Dadaboyev, Sherzodbek/JQV-8677-2023 | 57210810791; 57204128390; 57210820189 | yjbaek@knu.ac.kr; | INTERNATIONAL JOURNAL OF CONFLICT MANAGEMENT | INT J CONFL MANAGE | 1044-4068 | 1758-8545 | 32 | 2 | SSCI | COMMUNICATION | 2021 | 2.551 | 50.0 | 0.24 | 2025-07-30 | 3 | 4 | Task interdependence; Conservation of resources theory; In-role behavior; Victimization; Innovative behavior; Three-way interaction | ORGANIZATIONAL CITIZENSHIP BEHAVIOR; JOB DEMANDS; WORKPLACE; SELF; PERSONALITY; PERFORMANCE; RESISTANCE; RESOURCES; CONSERVATION; PERCEPTIONS | Conservation of resources theory; In-role behavior; Innovative behavior; Task interdependence; Three-way interaction; Victimization | English | 2021 | 2021-03-22 | 10.1108/ijcma-05-2020-0090 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Waterproof Galvanometer Scanner-Based Handheld Photoacoustic Microscopy Probe for Wide-Field Vasculature Imaging In Vivo | Photoacoustic imaging (PAI) is a hybrid non-invasive imaging technique used to merge high optical contrast and high acoustic resolution in deep tissue. PAI has been extensively developed by utilizing its advantages that include deep imaging depth, high resolution, and label-free imaging. As a representative implementation of PAI, photoacoustic microscopy (PAM) has been used in preclinical and clinical studies for its micron-scale spatial resolution capability with high optical absorption contrast. Several handheld and portable PAM systems have been developed that improve its applicability to several fields, making it versatile. In this study, we developed a laboratory-customized, two-axis, waterproof, galvanometer scanner-based handheld PAM (WP-GVS-HH-PAM), which provides an extended field of view (14.5 x 9 mm(2)) for wide-range imaging. The fully waterproof handheld probe enables free movement for imaging regardless of sample shape, and volume rate and scanning region are adjustable per experimental conditions. Results of WP-GVS-HH-PAM-based phantom and in vivo imaging of mouse tissues (ear, iris, and brain) confirm the feasibility and applicability of our system as an imaging modality for various biomedical applications. | Seong, Daewoon; Han, Sangyeob; Lee, Jaeyul; Lee, Euimin; Kim, Yoonseok; Lee, Junsoo; Jeon, Mansik; Kim, Jeehyun | Kyungpook Natl Univ, Coll IT Engn, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Med, Inst Biomed Engn, Daegu 41566, South Korea; Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA | ; Lee, Jung Bok/HHZ-3200-2022; Han, Sangyeob/W-3206-2018; Lee, Junsoo/IUO-9627-2023 | 57212512353; 57193695305; 57188689420; 57223052911; 57216828837; 57209986073; 24171094000; 7601373350 | smc7095@knu.ac.kr;syhan850224@knu.ac.kr;jaeyul21@g.ucla.edu;augustmini@knu.ac.kr;otter0618@knu.ac.kr;jslee5399@knu.ac.kr;msjeon@knu.ac.kr;jeehk@knu.ac.kr; | PHOTONICS | PHOTONICS-BASEL | 2304-6732 | 8 | 8 | SCIE | OPTICS | 2021 | 2.536 | 50.0 | 0.67 | 2025-07-30 | 11 | 9 | photoacoustic microscopy; handheld probe; wide-field imaging; in vivo vasculature imaging; 3D imaging | HIGH-RESOLUTION; HIGH-SPEED; TOMOGRAPHY | 3D imaging; Handheld probe; In vivo vasculature imaging; Photoacoustic microscopy; Wide-field imaging | English | 2021 | 2021-08 | 10.3390/photonics8080305 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Adaptive Decrease Window for BALIA (ADW-BALIA): Congestion Control Algorithm for Throughput Improvement in Nonshared Bottlenecks | The main design goals of the multipath transmission control protocol (MPTCP) are to improve the throughput and share a common bottleneck link fairly with a single-path transmission control protocol (TCP). The existing MPTCP congestion control algorithms achieve the goal of fairness with single-path TCP flows in a shared bottleneck, but they cannot maximize the throughput in nonshared bottlenecks, where multiple subflows traverse different bottleneck links. This is because the MPTCP is designed not to exceed the throughput of a single-path TCP competing in the bottleneck. Therefore, we believe that MPTCP congestion control should have different congestion window control mechanisms, depending on the bottleneck type. In this paper, we propose an adaptive decrease window (ADW) balanced linked adaptation (BALIA) congestion control algorithm that adaptively adjusts the congestion window decrease in order to achieve better throughput in nonshared bottlenecks while maintaining fairness with the single-path TCP flows in shared bottlenecks. The ADW-BALIA algorithm detects shared and nonshared bottlenecks based on delay fluctuations and it uses different congestion window decrease methods for the two types of bottleneck. When the delay fluctuations of the MPTCP subflows are similar, the ADW-BALIA algorithm behaves the same as the existing BALIA congestion control algorithm. If the delay fluctuations are dissimilar, then the ADW-BALIA algorithm adaptively modulates the congestion window reduction. We implement the ADW-BALIA algorithm in the Linux kernel and perform an emulation experiment that is based on various topologies. ADW-BALIA improves the aggregate MPTCP throughput by 20% in the nonshared bottleneck scenario, while maintaining fairness with the single-path TCP in the shared bottleneck scenario. Even in a triple bottleneck topology, where both types of bottlenecks exist together, the throughput increases significantly. We confirmed that the ADW-BALIA algorithm works stably for different delay paths, in competition with CUBIC flows, and with lossy links. | Kim, Geon-Hwan; Song, Yeong-Jun; Mahmud, Imtiaz; Cho, You-Ze | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea | Mahmud, Imtiaz/R-1089-2019 | 57189040274; 57210919165; 56203487900; 7404469829 | kgh76@ee.knu.ac.kr;syj5385@knu.ac.kr;imtiaz.tee@gmail.com;yzcho@ee.knu.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 3 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.26 | 2025-07-30 | 3 | 4 | multipath transmission control protocol (MPTCP); congestion control; nonshared bottleneck; fairness; throughput | Congestion control; Fairness; Multipath transmission control protocol (MPTCP); Nonshared bottleneck; Throughput | English | 2021 | 2021-02 | 10.3390/electronics10030294 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | An Efficient On-Demand Hardware Replacement Platform for Metamorphic Functional Processing in Edge-Centric IoT Applications | The paradigm of Internet-of-things (IoT) systems is changing from a cloud-based system to an edge-based system. These changes were able to solve the delay caused by the rapid concentration of data in the communication network, the delay caused by the lack of server computing capacity, and the security issues that occur in the data communication process. However, edge-based IoT systems performance was insufficient to process large numbers of data due to limited power supply, fixed hardware functions, and limited hardware resources. To improve their performance, application-specific hardware can be installed in edge devices, but performance cannot be improved except for specific applications due to a fixed function of an application-specific hardware. This paper introduces an edge-centric metamorphic IoT (mIoT) platform that can use various hardware modules through on-demand partial reconfiguration, despite the limited hardware resources of edge devices. In addition, this paper introduces an RISC-V based metamorphic IoT processor (mIoTP) with reconfigurable peripheral modules. We experimented to prove that the proposed structure can reduce the server access of edges and can be applied to a large-scale IoT system. Experiments were conducted in a single-edge environment and a large-scale environment combining one physical edge and 99 virtual edges. According to the experimental results, the edge-centric mIoT platform that executes the reconfiguration prediction algorithm at the edge was able to reduce the number of server accesses by up to 82.2% compared to our previous study in which the prediction process was executed at the server. Furthermore, we confirmed that there is no additional reconfiguration time overhead even for the large IoT systems. | Moon, Hyeongyun; Park, Daejin | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | 57206508978; 55463943600 | moonhg1209@gmail.com;boltanut@knu.ac.kr; | ELECTRONICS | ELECTRONICS-SWITZ | 2079-9292 | 10 | 17 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2021 | 2.69 | 50.2 | 0.19 | 2025-07-30 | 3 | 3 | IoT (Internet of Things); hardware reconfiguration; edge computing; metamorphic platform | INTERNET; THINGS; CLOUD; INTEGRATION; CHALLENGES | Edge computing; Hardware reconfiguration; IoT (Internet of Things); Metamorphic platform | English | 2021 | 2021-09 | 10.3390/electronics10172088 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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