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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Can Current Recommendations on Sun Exposure Sufficiently Increase Serum Vitamin D Level?: One-Month Randomized Clinical Trial | Background: Lack of sunlight exposure is the primary reason for the worldwide epidemic of vitamin D deficiency. Although recommended sunlight exposure guidelines exist, there is no evidence regarding whether current guidelines are optimal for increasing vitamin D levels among individuals with vitamin D deficiency. Methods: Sixty Korean adults aged 20-49 years with serum 25-hydroxyvitamin D (25[OH) D) levels of >= 20 ng/mL at follow-up. The daily living group showed no difference in vitamin D levels (-0.7 ng/mL, P= 0.516). Conclusion: Sunlight exposure was not sufficient to overcome vitamin D insufficiency or deficiency in the current study subjects. Effectiveness of current sunlight exposure guidelines among various populations should be reassessed in larger clinical studies. | Lee, Yu-Mi; Kim, Se-A; Lee, Duk-Hee | Kyungpook Natl Univ, Sch Med, Dept Prevent Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Biomed Sci, Grad Sch, Daegu, South Korea; Kyungpook Natl Univ, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu, South Korea | 57075191600; 56311702800; 57211851121 | lee_dh@knu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 8 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.8 | 2025-06-25 | 38 | 17 | Vitamin D Deficiency; Sunlight Exposure; Vitamin D Supplementation; 25(OH)D; 1,25(OH)(2)D; Randomized Clinical Trial | HUMAN-SKIN; SUNLIGHT; HEALTH; METABOLISM; ADULTS | 1,25(OH)2D; 25(OH)D; Randomized clinical trial; Sunlight exposure; Vitamin D deficiency; Vitamin D supplementation | Adult; Dietary Supplements; Female; Guidelines as Topic; Humans; Male; Middle Aged; Seasons; Sunlight; Vitamin D; Young Adult; 25-hydroxyvitamin D; vitamin D; adult; blood; controlled study; dietary supplement; female; human; male; middle aged; practice guideline; randomized controlled trial; season; sunlight; young adult | English | 2020 | 2020-03-02 | 10.3346/jkms.2020.35.e50 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Changes in Characteristics of Patients with Liver Cirrhosis Visiting a Tertiary Hospital over 15 Years: a Retrospective Multi-Center Study in Korea | Background: Liver cirrhosis has become a heavy burden not only for patients, but also for our society. However, little is known about the recent changes in clinical outcomes and characteristics of patients with cirrhosis-related complications in Korea. Therefore, we aimed to evaluate changes in characteristics of patients with liver cirrhosis in Daegu-Gyeongbuk province in Korea over the past 15 years. Methods: We retrospectively reviewed the medical records of 15,716 liver cirrhotic patients from 5 university hospitals in Daegu-Gyeongbuk province from 2000 to 2014. The Korean Standard Classification of Diseases-6 code associated with cirrhosis was investigated through medical records and classified according to the year of first visit. Results: A total of 15,716 patients was diagnosed with cirrhosis. A number of patients newly diagnosed with cirrhosis has decreased each year. In 2000, patients were most likely to be diagnosed with hepatitis B virus (HBV) cirrhosis, followed by alcoholic cirrhosis. There was a significant decrease in HBV (P < 0.001), but alcohol, hepatitis C virus (HCV), and nonalcoholic fatty liver disease (NAFLD) showed a significant increase during the study period (alcohol, P = 0.036; HCV, P = 0.001; NAFLD, P = 0.001). At the time of initial diagnosis, the ratio of Child-Turcotte-Pugh (CTP) class A gradually increased from 23.1% to 32.9% (P < 0.001). The most common cause of liver-related hospitalization in 2000 was hepatocellular carcinoma (HCC) (25.5%); in 2014, gastrointestinal bleeding with esophageal and gastric varices (21.4%) was the most common cause. Cases of hospitalization with liver-related complication represented 76.4% of all cases in 2000 but 70.9% in 2014. Incidence rate of HCC has recently increased. In addition, HCC-free survival was significantly lower in CTP class A than in classes B and C. Finally, there was significant difference in HCC occurrence according to causes (P < 0.001). HBV and HCV cirrhosis had lower HCC-free survival than alcoholic and NAFLD cirrhosis. Conclusion: In recent years, the overall number of cirrhosis patients has decreased. This study confirmed the recent trend in decrease of cirrhosis, especially of cirrhosis due to HBV, and the increase of HCV, alcoholic and NAFLD cirrhosis. Targeted screening for at-risk patients will facilitate early detection of liver diseases allowing effective intervention and may have decreased the development of cirrhosis and its complications. | Jang, Won Young; Chung, Woo Jin; Jang, Byoung Kuk; Hwang, Jae Seok; Lee, Heon Ju; Hwang, Moon Joo; Kweon, Young Oh; Tak, Won Young; Park, Soo Young; Lee, Su Hyun; Lee, Chang Hyeong; Kim, Byung Seok; Kim, Si Hye; Suh, Jeong Ill; Park, Jun Gi | Keimyung Univ, Dept Internal Med, Sch Med, 1095 Dalgubeol Daero, Daegu 42601, South Korea; Yeungnam Univ, Dept Internal Med, Coll Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Catholic Univ, Dept Internal Med, Daegu Sch Med, Daegu, South Korea; Dongguk Univ, Dept Internal Med, Coll Med, Gyeongju, South Korea | KIM, YOUNG JIN/E-9374-2011; park, soo-young/N-3170-2017; Kim, Seul Kee/A-6076-2015; Lee, Hyo-Suk/J-5618-2012 | 57218289218; 55741230500; 58849853600; 57205851488; 55085510500; 57097504300; 7004694832; 7004074582; 57191674344; 56592477600; 55784781600; 55974276800; 55263366100; 7201515001; 57217685855 | chung50@dsmc.or.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 29 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.4 | 2025-06-25 | 9 | 9 | Liver Cirrhosis; Hepatocellular Carcinoma; Epidemiology | C VIRUS-INFECTION; HEPATITIS-B; HEPATOCELLULAR-CARCINOMA; CLINICAL-OUTCOMES; RISK; EPIDEMIOLOGY; STRATEGIES | Epidemiology; Hepatocellular carcinoma; Liver cirrhosis | Adult; Aged; Carcinoma, Hepatocellular; Female; Hepatitis B; Hepatitis C; Hospitalization; Humans; Kaplan-Meier Estimate; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Neoplasms; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Republic of Korea; Retrospective Studies; Risk Factors; Severity of Illness Index; Tertiary Care Centers; adult; aged; alcohol liver cirrhosis; clinical trial; complication; female; hepatitis B; hepatitis C; hospitalization; human; Kaplan Meier method; liver cell carcinoma; liver cirrhosis; liver tumor; male; middle aged; mortality; multicenter study; nonalcoholic fatty liver; pathology; retrospective study; risk factor; severity of illness index; South Korea; tertiary care center | English | 2020 | 2020-07-27 | 10.3346/jkms.2020.35.e233 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Characteristics of Acute Stroke in Patients with Coronavirus Disease 2019 and Challenges in Stroke Management during an Epidemic | Coronavirus disease 2019 (COVID-19) is an ongoing pandemic infection associated with high morbidity and mortality. The Korean city of Daegu endured the first large COVID-19 outbreak outside of China. Since the report of the first confirmed case in Daegu on February 18, 2020, a total of 6,880 patients have been reported until May 29, 2020. We experienced five patients with ischemic stroke and COVID-19 during this period in four tertiary hospitals in Daegu. The D-dimer levels were high in all three patients in whom D-dimer blood testing was performed. Multiple embolic infarctions were observed in three patients and suspected in one. The mean time from stroke symptom onset to emergency room arrival was 22 hours. As a result, acute treatment for ischemic stroke was delayed. The present case series report raises the possibility that the coronavirus responsible for COVID-19 causes or worsens stroke, perhaps by inducing inflammation. The control of COVID-19 is very important; however, early and proper management of stroke should not be neglected during the epidemic. | Kwon, Doo Hyuk; Do, Youngrok; Eun, Mi-Yeon; Lee, Jun; Park, Hyungjong; Sohn, Sung-Il; Hong, Jeong-Ho | Keimyung Univ, Daegu Dongsan Hosp, Dept Neurol, Sch Med, Daegu, South Korea; Catholic Univ Daegu, Daegu Catholic Univ Hosp, Dept Neurol, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurol, Daegu, South Korea; Yeungnam Univ, Yeungnam Univ Hosp, Dept Neurol, Sch Med, Daegu, South Korea; Keimyung Univ, Keimyung Univ Dongsan Hostpial, Dept Neurol, Sch Med, Daegu, South Korea | ; Eun, Mi-Yeon/AAV-2877-2021; Hong, Jeong-Ho/AAE-1002-2022; Park, Hyungjong/AAI-5361-2020; Hong, Jeong-Ho/T-8099-2018 | 57216938491; 57203177485; 36463396500; 55894819500; 57199865406; 36479287000; 55931654800 | neurohong79@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 35 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.64 | 2025-06-25 | 8 | 8 | Ischemic Stroke; Coronavirus Disease; Korea; Stroke Management; D-dimer | Coronavirus disease; D-dimer; Ischemic stroke; Korea; Stroke management | Aged; Aged, 80 and over; Betacoronavirus; Coronavirus Infections; Cytokines; Emergency Medical Services; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Middle Aged; Pandemics; Pneumonia, Viral; Republic of Korea; Stroke; Thromboembolism; Thrombolytic Therapy; Time-to-Treatment; cytokine; fibrin degradation product; fibrin fragment D; aged; Betacoronavirus; blood; case report; cerebrovascular accident; Coronavirus infection; emergency health service; female; fibrinolytic therapy; human; male; middle aged; mortality; pandemic; pathology; procedures; South Korea; thromboembolism; time to treatment; very elderly; virus pneumonia | English | 2020 | 2020-09-07 | 10.3346/jkms.2020.35.e324 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Characteristics of Ocular Manifestations of Patients with Coronavirus Disease 2019 in Daegu Province, Korea | Background: The coronavirus disease 2019 (COVID-19) has reportedly affected almost 23 million people, with more than 800 thousand deaths globally. There have been a few reports on the ocular manifestations of COVID-19 patients in China but no reports in Korea. The present study aimed to examine ocular manifestations of COVID-19 patients in Korea. Methods: COVID-19 patients admitted from March 2020 to April 2020 at Keimyung University Dongsan Hospital and Keimyung University Daegu Dongsan Hospital were reviewed retrospectively for ocular manifestations. During the period of hospitalization, ocular symptoms as well as blood test results were noted and analyzed. Patients were then divided into the first-episode and relapsed group and ocular symptoms were analyzed in the groups. Results: A total of 103 patients were included in this study. Among them, 71 patients were in the first-episode group and 32 patients in the relapsed group. No significant differences were determined in terms of positivity of ocular symptoms between the first-episode group (12 patients, 16.9%) and the relapsed group (10 patients, 31.3%, P > 0.05). Symptoms of positive upper respiratory infection and lower creatine phosphokinase were determined to be related to positive ocular symptoms. Conjunctival congestion was noted in seven patients. In the subgroup analysis, the conjunctival congestion-positive patients exhibited higher positivity of upper respiratory infection symptoms (100%) as compared with those in the negative group (40%, P = 0.017). Conclusion: Positive upper respiratory infection symptoms and lower creatine phosphokinase were determined to be related to ocular symptoms in COVID-19 patients. Among these patients, positive upper respiratory infection symptoms were associated with conjunctival congestion. | Lee, You Hyun; Kim, Yu Cheol; Shin, Jae Pil | Keimyung Univ, Sch Med, Dept Ophthalmol, Daegu Dongsan Hosp, Daegu, South Korea; Keimyung Univ, Sch Med, Dept Ophthalmol, Dongsan Hosp, 1035 Dalgubeoldae Ro, Daegu 42601, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Ophthalmol, Daegu, South Korea | Lee, You Hyun/ISV-2828-2023; Kim, Yucheol/LRS-9072-2024 | 57191708556; 57209137254; 56517350400 | eyedr@dsmc.or.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 35 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.72 | 2025-06-25 | 8 | 11 | Coronavirus; COVID-19; Conjunctival Congestion; Ocular Manifestations | CLINICAL CHARACTERISTICS | Conjunctival congestion; Coronavirus; COVID-19; Ocular manifestations | Adult; Betacoronavirus; C-Reactive Protein; Conjunctival Diseases; Coronavirus Infections; Creatine Kinase; Dry Eye Syndromes; Female; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Pandemics; Pneumonia, Viral; Procalcitonin; Republic of Korea; Retrospective Studies; Vision Disorders; C reactive protein; creatine kinase; lactate dehydrogenase; procalcitonin; adult; Betacoronavirus; blood; conjunctiva disease; Coronavirus infection; dry eye; female; human; male; middle aged; pandemic; pathogenicity; pathology; retrospective study; South Korea; virology; virus pneumonia; visual disorder | English | 2020 | 2020-09-07 | 10.3346/jkms.2020.35.e322 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January-May 2020 | Background: The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity of healthcare systems, and the quality of medical care. We assessed the clinical outcomes of patients with COVID-19 during the first wave of the epidemic in Korea. Methods: Using a modified World Health Organization clinical record form, we obtained clinical data for 3,060 patients with COVID-19 treated at 55 hospitals in Korea. Disease severity scores were defined as: 1) no limitation of daily activities; 2) limitation of daily activities but no need for supplemental oxygen; 3) supplemental oxygen via nasal cannula; 4) supplemental oxygen via facial mask; 5) non-invasive mechanical ventilation; 6) invasive mechanical ventilation; 7) multi-organ failure or extracorporeal membrane oxygenation therapy; and 8) death. Recovery was defined as a severity score of 1 or 2, or discharge and release from isolation. Results: The median age of the patients was 43 years of age; 43.6% were male. The median time from illness onset to admission was 5 days. Of the patients with a disease severity score of 3-4 on admission, 65 (71.5%) of the 91 patients recovered, and 7 (7.7%) died due to illness by day 28. Of the patients with disease severity scores of 5-7, 7 (19.5%) of the 36 patients recovered, and 8 (22.2%) died due to illness by day 28. None of the 1,324 patients who were = 80 years of age, respectively. Conclusion: In Korea, almost all patients of = 50 years of age, the fatality rate increased with age, reaching 14% in patients of >= 80 years of age. | Sung, Ho Kyung; Kim, Jin Yong; Heo, Jeonghun; Seo, Haesook; Jang, Young Soo; Kim, Hyewon; Koh, Bo Ram; Jo, Neungsun; Oh, Hong Sang; Baek, Young Mi; Park, Kyung-Hwa; Shon, Jeung A.; Kim, Min-Chul; Kim, Joon Ho; Chang, Hyun-Ha; Park, Yukyung; Kang, Yu Min; Lee, Dong Hyun; Oh, Dong Hyun; Park, Hyun Jung; Song, Kyoung-Ho; Lee, Eun Kyoung; Jeong, Hyeongseok; Lee, Ji Yeon; Ko, Ja-Young; Choi, Jihee; Ryu, Eun Hwa; Chung, Ki-hyun; Oh, Myoung-don | Natl Med Ctr, Natl Emergency Med Ctr, Seoul, South Korea; Incheon Med Ctr, Dept Internal Med, Div Infect Dis, Incheon, South Korea; Busan Med Ctr, Dept Pulmonol, Busan, South Korea; Seoul Metropolitan Seobuk Hosp, Dept TB, Seoul, South Korea; Seoul Metropolitan Seonam Hosp, Dept Orthoped Surg, Seoul, South Korea; Chungju Med Ctr, Dept Lab Med, Chungju, South Korea; Gyeonggi Prov Med Ctr, Dept Internal Med, Ansung Hosp, Anseong, South Korea; Chungcheongnam Do Gongju Med Ctr, Dept Infect Control, Gongju, South Korea; Armed Forces Capital Hosp, Dept Internal Med, Div Infect Dis, Seongnam, South Korea; Chungcheongnam Seosan Med Ctr, Dept Infect Control, Seosan, South Korea; Chonnam Natl Univ, Dept Infect Dis, Med Sch, Gwangju, South Korea; Yeongju Red Cross Hosp, Dept Nursing, Yeongju, South Korea; Chung Ang Univ Hosp, Dept Internal Med, Div Infect Dis, Seoul, South Korea; Gyeonggi Prov Med Ctr, Dept Surg, Uijeongbu Hosp, Uijongbu, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Infect Dis, Daegu, South Korea; Korea Workers Compensat & Welf Serv, Dept Internal Med, Daegu Hosp, Daegu, South Korea; Myongji Hosp, Dept Internal Med, Div Infect Dis, Goyang, South Korea; Chungcheongnam Do Cheonan Med Ctr, Dept Internal Med, Cheonan, South Korea; Seoul Med Ctr, Dept Internal Med, Div Infect Dis, Seoul, South Korea; Jeonllanam Do Suncheon Med Ctr, Dept Internal Med, Sunchon, South Korea; Seoul Natl Univ, Dept Internal Med, Div Infect Dis, Bundang Hosp, Seongnam, South Korea; Cheongju Med Ctr, Infect Control Team, Cheongju, South Korea; Chungnam Natl Univ, Dept Internal Med, Div Infect Dis, Sch Med, Daejeon, South Korea; Keimyung Univ, Dept Internal Med, Div Infect Dis, Dongsan Hosp, Daegu, South Korea; Gyeonggi Prov Med Ctr, Paju Hosp, Intens Care Team, Paju, South Korea; Gyeonggi Prov Med Ctr, Icheon Hosp, Infect Control Team, Icheon, South Korea; Korea Workers Compensat & Welf Serv, Changwon Hosp, Infect Control Team, Chang Won, South Korea; Natl Med Ctr, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Internal Med, Coll Med, Seoul, South Korea | Oh, Hong Sang/GZL-1065-2022; Kim, Min Chul/IYJ-9897-2023; Kim, Jung/L-9791-2019; Kim, Soon Hee/GXF-6736-2022; Sung, Ho Kyung/LSL-4710-2024; Oh, Dong/AAO-8832-2020 | 57214169573; 57211142178; 57218362936; 37666048000; 57218360869; 59051328900; 57216275479; 57218360375; 56909332000; 57218361558; 57219637574; 57218362281; 57212315585; 57218363128; 7407521688; 57217294505; 55267459000; 57218362235; 55241215000; 57218362855; 23398486700; 57199433801; 57218219136; 57216774221; 57218360980; 57218362263; 57218362598; 57216275353; 7201600302 | mdohmd@snu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 30 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 4.22 | 2025-06-25 | 53 | 56 | COVID-19; SARS-CoV-2; Prognosis; Cohort Study; Korea | Cohort study; COVID-19; Korea; Prognosis; SARS-CoV-2 | Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Coronavirus Infections; Data Collection; Disease Progression; Female; Geography; Hospitalization; Humans; Infant; Infant, Newborn; Male; Middle Aged; Mortality; Outcome Assessment, Health Care; Pandemics; Patient Isolation; Pneumonia, Viral; Republic of Korea; Respiration, Artificial; Severity of Illness Index; Surge Capacity; Treatment Outcome; World Health Organization; Young Adult; adolescent; adult; aged; artificial ventilation; child; Coronavirus infection; disease exacerbation; female; geography; hospitalization; human; infant; information processing; male; middle aged; mortality; newborn; pandemic; patient isolation; preschool child; severity of illness index; South Korea; surge capacity; treatment outcome; very elderly; virus pneumonia; World Health Organization; young adult | English | 2020 | 2020-08-03 | 10.3346/jkms.2020.35.e280 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical Impact of Implantable Cardioverter-Defibrillator Therapy and Mortality Prediction Model for Effective Primary Prevention in Korean Patients | Background: Studies on the efficacy of implantable cardioverter-defibrillator (ICD) therapy for primary prevention in Asian patients are relatively lacking compared to those for secondary prevention. Also, it is important to stratify which patients will benefit from ICD therapy for primary prevention. Methods: Of 483 consecutive patients who received new implantation of ICD in 9 centers in Korea, 305 patients with reduced left ventricular systolic function and/or documented ventricular fibrillation/tachycardia were enrolled and divided into primary (n = 167) and secondary prevention groups (n = 138). Results: During mean follow-up duration of 2.6 +/- 1.6 years, appropriate ICD therapy occurred in 78 patients (25.6%), and appropriate ICD shock and anti-tachycardia pacing occurred in 15.1% and 15.1% of patients, respectively. Appropriate ICD shock rate was not different between the two groups (primary 12% vs. secondary 18.8%, P = 0.118). However, appropriate ICD therapy rate including shock and anti-tachycardia pacing was significantly higher (primary 18% vs. secondary 34.8%, P = 0.001) in the secondary prevention group. Type of prevention and etiology, appropriate and inappropriate ICD shock did not affect all-cause death. High levels of N-terminal pro-B-type natriuretic peptide, New York Heart Association functional class, low levels of estimated glomerular filtration ratio, and body mass index were associated with death before appropriate ICD shock in the primary prevention group. When patients were categorized in 5 risk score groups according to the sum of values defined by each cut-off level, significant differences in death rate before appropriate ICD shock were observed among risk 0 (0%), 1 (3.6%), 2 (3%), 3 (26.5%), and 4 (40%) (P < 0.001). Conclusion: In this multicenter regional registry, the frequency of appropriate ICD therapy is not low in the primary prevention group. In addition, combination of poor prognostic factors of heart failure is useful in risk stratification of patients who are not benefiting from ICD therapy for primary prevention. | Bae, Myung Hwan; Cho, Yongkeun; Hwang, Jongmin; Park, Hyoung-Seob; Han, Seongwook; Lee, Young Soo; Cho, Hyun Jun; Jung, Byung Chun; Lee, Chan-Hee; Hyun, Dae-Woo; Park, Jong Sung; Ahn, Jinhee; Kim, Ki-Hun; Shin, Dong-Gu | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Keimyung Univ, Dept Internal Med, Dongsan Med Ctr, Daegu, South Korea; Daegu Catholic Univ, Dept Internal Med, Med Ctr, Daegu, South Korea; Daegu Fatima Gen Hosp, Dept Internal Med, Daegu, South Korea; Yeungnam Univ, Dept Internal Med, Med Ctr, 170 Hyeonchung Ro, Daegu 42415, South Korea; Andong Gen Hosp, Dept Internal Med, Andong, South Korea; Dong A Univ Hosp, Dept Internal Med, Busan, South Korea; Pusan Natl Univ Hosp, Dept Internal Med, Busan, South Korea; Inje Univ, Dept Internal Med, Busan Haeundae Paik Hosp, Busan, South Korea | ; Kim, Seong Cheol/ABD-1493-2022 | 36607356800; 9249593500; 57215648513; 36175197800; 7405944969; 56368143800; 39161095700; 8042202500; 36045642800; 55666084700; 54781638800; 56560475600; 34770981100; 14045949300 | dgshin@med.yu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 9 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.24 | 2025-06-25 | 5 | 6 | Implantable Cardioverter-Defibrillator; Primary Prevention; Risk Assessment | ANTIARRHYTHMIC-DRUG THERAPY; HEART-FAILURE; TRIAL; ASSOCIATION; PROGNOSIS | Implantable cardioverter-defibrillator; Primary prevention; Risk assessment | Aged; Cardiomyopathies; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Female; Follow-Up Studies; Heart Ventricles; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Primary Prevention; Proportional Hazards Models; Registries; Republic of Korea; Risk Factors; Treatment Outcome; Ventricular Dysfunction, Left; brain natriuretic peptide; peptide fragment; pro-brain natriuretic peptide (1-76); adverse device effect; aged; blood; cardiomyopathy; complication; electrocardiography; female; follow up; heart left ventricle function; heart ventricle; human; implantable cardioverter defibrillator; Kaplan Meier method; male; middle aged; mortality; pathophysiology; primary prevention; proportional hazards model; register; risk factor; South Korea; sudden cardiac death; treatment outcome | English | 2020 | 2020-03-09 | 10.3346/jkms.2020.35.e49 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | COVID-19 Outbreak and Its Association with Healthcare Workers' Emotional Stress: a Cross-Sectional Study | Background: The coronavirus disease 2019 (COVID-19) outbreak has exposed healthcare workers to extreme physical workloads and psychological challenges. Thus, we aimed to assess the immediate correlates of emotional stress and to identify which specific jobs, departments, and exposure types are risk factors for emotional stress in healthcare workers. Methods: In this cross-sectional study conducted from April 2 to 10, 2020, university hospital workers were administered self-reported questionnaires that covered general characteristics and included the Patient Health Questionnaire, Generalized Anxiety Disorder scale, and a visual analog scale. At-risk groups for depression and anxiety were identified, and the odds ratios for depression and anxiety were analyzed after adjusting for age, gender, education, marital status, and duration of employment. Results: The data of 1,003 participants were analyzed. Of these, 14.2% worked in wards for confirmed COVID-19 cases and 15.2% had had direct contact with these patients. Treating patients with COVID-19 was associated with depression and anxiety, while dealing with COVID-19 test samples was associated with depression. Exposure to random or unspecified patients was also associated with depression. Lastly, social rejection and other negative experiences were associated with depression and anxiety. Conclusion: The COVID-19 outbreak is correlated with healthcare workers' emotional stress, and specific types of jobs and duties involving close contact with these patients can be risk factors. Interestingly, even low-exposure groups reported significant depression and anxiety as a result of social stigma and uncertainty. Adequate and timely management measures for emotional stress are required for vulnerable and at-risk groups. | Park, Chulyong; Hwang, Jong-Moon; Jo, Seongmin; Bae, Seong Jin; Sakong, Joon | Yeungnam Univ Hosp, Dept Occupat & Environm Med, Daegu, South Korea; Yeungnam Univ, Coll Med, Dept Prevent Med & Publ Hlth, 170 Hyeonchung Ro, Daegu 42415, South Korea; Kyungpook Natl Univ Hosp, Dept Rehabil Med, Daegu, South Korea | Sakong, Joon/AFE-2002-2022; Park, Chulyong/AAN-1464-2020 | 57190335503; 56367634000; 57218242337; 57219699504; 6506105070 | jjsakong@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 41 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 2.07 | 2025-06-25 | 34 | 30 | COVID-19; Daegu; PHQ-9; GAD-7 | ACUTE RESPIRATORY SYNDROME; PSYCHOLOGICAL IMPACT; SARS OUTBREAK; DEPRESSION; PHQ-9; VALIDITY | COVID-19; Daegu; GAD-7; PHQ-9 | Adult; Anxiety; Coronavirus Infections; Cross-Sectional Studies; Depressive Disorder; Female; Health Personnel; Humans; Male; Middle Aged; Occupational Stress; Odds Ratio; Pandemics; Pneumonia, Viral; Republic of Korea; Risk Factors; Self Report; Social Distance; Workload; Young Adult; adult; anxiety; Coronavirus infection; cross-sectional study; depression; female; health care personnel; human; job stress; male; middle aged; odds ratio; pandemic; psychology; risk factor; self report; social distance; South Korea; virus pneumonia; workload; young adult | English | 2020 | 2020-10-26 | 10.3346/jkms.2020.35.e372 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Development of Antibiotic Classification for Measuring Antibiotic Usage in Korean Hospitals Using a Modified Delphi Method | In 2019, a project designed to develop a system for measuring and comparing antibiotic usage in hospitals was launched in Korea. As part of this project, we developed a means to classify antibiotic usage in Korean hospitals using a modified Delphi method. In results, the following categories of antibiotic classification were accepted for use in Korean hospitals: 1) broad-spectrum antibacterial agents predominantly used for hospital-onset infections in adults, 2) broad-spectrum antibacterial agents predominantly used for community-acquired infections in adults, 3) antibacterial agents predominantly used for resistant gram-positive infections in adults, 4) narrow-spectrum beta-lactam agents in adults, 5) antibacterial agents predominantly used for extensive antibiotic resistant gram-negative bacteria in adults, and 6) total antibacterial agents. | Kim, Bongyoung; Yoon, Young Kyung; Kim, Dong-Sook; Jeong, Su Jin; Ahn, Song Vogue; Park, Sun Hee; Kwon, Ki Tae; Kim, Hong Bin; Park, Yoon Soo; Kim, Shin-Woo; Kiem, Sungmin; Choi, Jun Yong | Hanyang Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Korea Univ, Dept Internal Med, Div Infect Dis, Coll Med, Seoul, South Korea; Dept Res Hlth Insurance Review & Assessment Serv, Wonju, South Korea; Yonsei Univ, Coll Med, Dept Internal Med, 50 Yonsei Ro, Seoul 03722, South Korea; Ewha Womans Univ, Dept Hlth Convergence, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Infect Dis, Daegu, South Korea; Seoul Natl Univ, Coll Med, Dept Internal Med, Div Infect Dis,Bundang Hosp, Seoul, South Korea; Chungnam Natl Univ, Sch Med, Sejong Hosp, Dept Infect Dis Internal Med, Sejong, South Korea | ; Hwang, Soyoon/HHM-5762-2022; Park, Yoon/C-6472-2015; Kim, Bongyoung/H-3409-2018; Kyung, Yoon/AAS-3428-2020; Kim, Hee/AAU-6368-2021; Kim, Hyuk Soon/IQW-9348-2023; Kim, Hong Bin/J-5452-2012; Choi, Jah/AAA-4835-2022; Kim, Woo/AAG-1822-2019; Ahn, Song/AAK-2900-2021; Kim, Sun/G-3451-2013 | 55622077200; 25947937900; 56109775000; 55545686800; 47360986600; 57208684295; 9733850500; 35307429400; 7405373036; 8710731500; 6603471324; 57791298700 | seran@yuhs.ac; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 30 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.16 | 2025-06-25 | 5 | 5 | Antibiotics; Stewardship; Hospitals; Measurement; Korea | INFECTIONS | Antibiotics; Hospitals; Korea; Measurement; Stewardship | Adult; Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Delphi Technique; Drug Resistance, Bacterial; Humans; antiinfective agent; adult; antibiotic resistance; classification; community acquired infection; cross infection; Delphi study; human | English | 2020 | 2020-08-03 | 10.3346/jkms.2020.35.e241 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Drive-Through Screening Center for COVID-19: a Safe and Efficient Screening System against Massive Community Outbreak | As the coronavirus disease 2019 (COVID-19) outbreak is ongoing, the number of individuals to be tested for COVID-19 is rapidly increasing. For safe and efficient screening for COVID-19, drive-through (DT) screening centers have been designed and implemented in Korea. Herein, we present the overall concept, advantages, and limitations of the COVID-19 DT screening centers. The steps of the DT centers include registration, examination, specimen collection, and instructions. The entire service takes about 10 minutes for one testee without leaving his or her cars. Increased testing capacity over 100 tests per day and prevention of cross-infection between testees in the waiting space are the major advantages, while protection of staff from the outdoor atmosphere is challenging. It could be implemented in other countries to cope with the global COVID-19 outbreak and transformed according to their own situations. | Kwon, Ki Tae; Ko, Jae-Hoon; Shin, Heejun; Sung, Minki; Kim, Jin Yong | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Med, Div Infect Dis,Sch Med, Seoul, South Korea; Soonchunhyang Univ Hosp, Dept Emergency Med, Bucheon, South Korea; Sejong Univ, Dept Architectural Engn, Seoul, South Korea; Incheon Med Ctr, Dept Internal Med, Div Infect Dis, 217 Bangchuk Ro, Incheon 22532, South Korea | Hwang, Soyoon/HHM-5762-2022; Shin, Heejun/R-1289-2018 | 9733850500; 55804188300; 57203345040; 56108483100; 57211142178 | kjykey@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 11 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 13.69 | 2025-06-25 | 92 | 183 | Drive-through; Screening; SARS-CoV-2; COVID-19; Outbreak | COVID-19; Drive-through; Outbreak; SARS-CoV-2; Screening | Automobiles; Betacoronavirus; Communicable Disease Control; Coronavirus Infections; Humans; Mass Screening; Pneumonia, Viral; Republic of Korea; COVID-19; severe acute respiratory syndrome coronavirus 2; Betacoronavirus; car; communicable disease control; coronavirus disease 2019; Coronavirus infection; human; mass screening; procedures; Severe acute respiratory syndrome coronavirus 2; South Korea; virus pneumonia | English | 2020 | 2020-03-23 | 10.3346/jkms.2020.35.e123 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Epidemiological Study of Hereditary Hemolytic Anemia in the Korean Pediatric Population during 1997-2016: a Nationwide Retrospective Cohort Study | Background: Hereditary hemolytic anemia (HHA) is a rare disease characterized by premature red blood cell (RBC) destruction due to intrinsic RBC defects. The RBC Disorder Working Party of the Korean Society of Hematology established and updated the standard operating procedure for making an accurate diagnosis of HHA since 2007. The aim of this study was to investigate a nationwide epidemiology of Korean HHA. Methods: We collected the data of a newly diagnosed pediatric HHA cohort (2007-2016) and compared this cohort's characteristics with those of a previously surveyed pediatric HHA cohort (1997-2006) in Korea. Each participant's information was retrospectively collected by a questionnaire survey. Results: A total of 369 children with HHA from 38 hospitals distributed in 16 of 17 districts of Korea were investigated. RBC membranopathies, hemoglobinopathies, RBC enzymopathies, and unknown etiologies accounted for 263 (71.3%), 59 (16.0%), 23 (6.2%), and 24 (6.5%) of the cases, respectively. Compared to the cohort from the previous decade, the proportions of hemoglobinopathies and RBC enzymopathies significantly increased (P < 0.001 and P = 0.008, respectively). Twenty-three of the 59 hemoglobinopathy patients had immigrant mothers, mostly from South-East Asia. Conclusion: In Korea, thalassemia traits have increased over the past 10 years, reflecting both increased awareness of this disease and increased international marriages. The enhanced recognition of RBC enzymopathies is due to advances in diagnostic technique; however, 6.5% of HHA patients still do not have a clear diagnosis. It is necessary to improve accessibility of diagnosing HHA. | Shim, Ye Jee; Jung, Hye Lim; Shin, Hee Young; Kang, Hyoung Jin; Choi, Jung Yoon; Hah, Jeong Ok; Lee, Jae Min; Lim, Young Tak; Yang, Eu Jeen; Baek, Hee Jo; Choi, Hyoung Soo; Yoo, Keon Hee; Park, Jun Eun; Kim, Seongkoo; Kim, Ji Yoon; Park, Eun Sil; Im, Ho Joon; Chueh, Hee Won; Kim, Soon Ki; Lee, Jae Hee; Yoo, Eun Sun; Park, Hyeon Jin; Lee, Jun Ah; Park, Meerim; Kang, Hyun Sik; Park, Ji Kyoung; Lee, Na Hee; Park, Sang Kyu; Lee, Young-Ho; Lee, Seong Wook; Choi, Eun Jin; Kong, Seom Gim | Keimyung Univ, Sch Med, Dept Pediat, Dongsan Med Ctr, Daegu, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Dept Pediat, 29 Saemunan Ro, Seoul 03181, South Korea; Seoul Natl Univ, Childrens Hosp, Canc Res Inst, Dept Pediat,Coll Med, 103 Daehak Ro, Seoul 03080, South Korea; Daegu Fatima Hosp, Dept Pediat, Daegu, South Korea; Yeungnam Univ, Dept Pediat, Coll Med, Daegu, South Korea; Pusan Natl Univ, Pusan Natl Univ Childrens Hosp, Dept Pediat, Sch Med, Yangsan, South Korea; Chonnam Natl Univ, Hwasun Hosp, Dept Pediat, Med Sch, Gwangju, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Pediat, Coll Med, Seongnam, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Pediat, Sch Med, Seoul, South Korea; Ajou Univ, Dept Pediat, Sch Med, Suwon, South Korea; Catholic Univ Korea, Coll Med, Dept Pediat, Seoul St Marys Hosp, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Pediat, Daegu, South Korea; Gyeongsang Natl Univ, Gyeongsang Natl Univ Hosp, Dept Pediat, Coll Med, Jinju, South Korea; Univ Ulsan, Asan Med Ctr, Dept Pediat, Coll Med,Childrens Hosp, Seoul, South Korea; Dong A Univ, Dept Pediat, Coll Med, Busan, South Korea; Inha Univ Hosp, Dept Pediat, Incheon, South Korea; Chosun Univ Hosp, Dept Pediat, Gwangju, South Korea; Ewha Womans Univ, Seoul Hosp, Dept Pediat, Coll Med, Seoul, South Korea; Natl Canc Ctr, Ctr Pediat Canc, Dept Pediat, Goyang, South Korea; Jeju Natl Univ, Jeju Natl Univ Hosp, Dept Pediat, Sch Med, Jeju, South Korea; Inje Univ, Busan Paik Hosp, Dept Pediat, Coll Med, Busan, South Korea; Cha Univ, Cha Bundang Med Ctr, Dept Pediat, Seongnam, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Pediat, Coll Med, Ulsan, South Korea; Hanyang Univ, Dept Pediat, Seoul Hosp, Seoul, South Korea; Korea Univ, Ansan Hosp, Dept Pediat, Coll Med, Ansan, South Korea; Daegu Catholic Univ, Dept Pediat, Sch Med, Daegu, South Korea; Kosin Univ, Gospel Hosp, Dept Pediat, Coll Med, Busan, South Korea | ; Park, Jun/AAL-8733-2020; Park, Jung Hoon/CZZ-0090-2022; Choi, Jungyoon/AAA-3883-2021; Lee, Jae Min/H-8475-2013 | 57222517942; 7403029925; 56582799400; 7404071502; 57102078500; 7003942219; 39261799700; 7402565128; 56594276100; 36724802200; 24576435400; 35304229600; 35488820600; 55486370800; 57205408095; 26030635800; 14524798500; 39261421100; 55190025100; 57206731882; 20936704200; 35739156500; 23097522100; 36626096800; 54401204700; 35332704400; 58425859900; 57209835309; 43262250600; 56480908500; 35075812900; 36982973800 | hl.jung@samsung.com;hyshin@snu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 33 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.8 | 2025-06-25 | 15 | 14 | Congenital Hemolytic Anemia; Hereditary Spherocytosis; Hemoglobinopathies; Thalassemia; Glucose-6-phosphate Dehydrogenase Deficiency; Pyruvate Kinase | PYRUVATE-KINASE DEFICIENCY; MOLECULAR CHARACTERIZATION; WORKING PARTY; THALASSEMIA; DIAGNOSIS; MUTATIONS; SOCIETY | Congenital hemolytic anemia; Glucose-6-phosphate dehydrogenase deficiency; Hemoglobinopathies; Hereditary spherocytosis; Pyruvate kinase; Thalassemia | Adolescent; Anemia, Hemolytic, Congenital; Anemia, Hemolytic, Congenital Nonspherocytic; Child; Child, Preschool; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobinopathies; Hemoglobins; Hospitals; Humans; Infant; Infant, Newborn; Male; Polymorphism, Genetic; Pyruvate Kinase; Pyruvate Metabolism, Inborn Errors; Republic of Korea; Retrospective Studies; Surveys and Questionnaires; hemoglobin; hemoglobin B; pyruvate kinase; adolescent; child; disorders of carboxylic acid metabolism; female; genetic polymorphism; genetics; glucose 6 phosphate dehydrogenase deficiency; hemoglobinopathy; hereditary hemolytic anemia; hospital; human; infant; male; newborn; preschool child; questionnaire; retrospective study; South Korea | English | 2020 | 2020-08-24 | 10.3346/jkms.2020.35.e279 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Establishment of a Nationwide Korean Imaging Cohort of Coronavirus Disease 2019 | Background: The Korean Society of Thoracic Radiology (KSTR) recently constructed a nation-wide coronavirus disease 2019 (COVID-19) database and imaging repository, referred to the Korean imaging cohort of COVID-19 (KICC-19) based on the collaborative efforts of its members. The purpose of this study was to provide a summary of the clinico-epidemiological data and imaging data of the KICC-19. Methods: The KSTR members at 17 COVID-19 referral centers retrospectively collected imaging data and clinical information of consecutive patients with reverse transcription polymerase chain reaction-proven COVID-19 in respiratory specimens from February 2020 through May 2020 who underwent diagnostic chest computed tomography (CT) or radiograph in each participating hospital. Results: The cohort consisted of 239 men and 283 women (mean age, 52.3 years; age range, 11-97 years). Of the 522 subjects, 201 (38.5%) had an underlying disease. The most common symptoms were fever (n = 292) and cough (n = 245). The 151 patients (28.9%) had lymphocytopenia, 86 had (16.5%) thrombocytopenia, and 227 patients (43.5%) had an elevated CRP at admission. The 121 (23.4%) needed nasal oxygen therapy or mechanical ventilation (n = 38; 7.3%), and 49 patients (9.4%) were admitted to an intensive care unit. Although most patients had cured, 21 patients (4.0%) died. The 465 (89.1%) subjects underwent a low to standard-dose chest CT scan at least once during hospitalization, resulting in a total of 658 CT scans. The 497 subjects (95.2%) underwent chest radiography at least once during hospitalization, which resulted in a total of 1,475 chest radiographs. Conclusion: The KICC-19 was successfully established and comprised of 658 CT scans and 1,475 chest radiographs of 522 hospitalized Korean COVID-19 patients. The KICC-19 will provide a more comprehensive understanding of the clinical, epidemiological, and radiologic characteristics of patients with COVID-19. | Yoon, Soon Ho; Ham, Soo-Youn; Nam, Bo Da; Chae, Kum Ju; Lee, Dabee; Yoo, Jin Young; Bak, So Hyeon; Kim, Jin Young; Kim, Jin Hwan; Kim, Ki Beom; Jung, Jung Im; Lim, Jae-Kwang; Lee, Jong Eun; Chung, Myung Jin; Lee, Young Kyung; Kim, Young Seon; Jo, Ji Eun; Lee, Sang Min; Kwon, Woocheol; Park, Chang Min; Kim, Yun-Hyeon; Jeong, Yeon Joo | Seoul Natl Univ Hosp, Dept Radiol, Seoul Natl Coll Med, Seoul, South Korea; Kangbuk Samsung Hosp, Dept Radiol, Seoul, South Korea; Soonchunhyang Univ, Coll Med, Dept Radiol, Seoul Hosp, Seoul, South Korea; Jeonbuk Natl Univ, Dept Radiol, Res Inst Clin, Biomed Res Inst, Jeonju, South Korea; Dankook Univ Hosp, Dept Radiol, Cheonan, South Korea; Chungbuk Natl Univ Hosp, Dept Radiol, Cheongju, South Korea; Keimyung Univ, Sch Med, Dept Radiol, Dongsan Hosp, Daegu, South Korea; Keimyung Univ, Sch Med, Dept Radiol, Dongsan Hosp, Daegu, South Korea; Chungnam Natl Univ Hosp, Dept Radiol, Coll Med, Daejeon, South Korea; Daegu Fatima Hosp, Dept Radiol, Daegu, South Korea; Sungkyunkwan Univ, Dept Radiol, Samsung Med Ctr, Sch Med, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiol, Daegu, South Korea; Chonnam Natl Univ Hosp, Dept Radiol, Gwangju, South Korea; Sungkyunkwan Univ, Dept Radiol, Samsung Med Ctr, Sch Med, Seoul, South Korea; Seoul Med Ctr, Dept Radiol, Seoul, South Korea; Yeungnam Univ, Coll Med, Dept Radiol, Yeungnam Univ Hosp, Daegu, South Korea; Busan Med Ctr, Dept Radiol, Busan, South Korea; Univ Ulsan, Dept Radiol, Asan Med Ctr, Coll Med, Seoul, South Korea; Univ Ulsan, Res Inst Radiol, Asan Med Ctr, Coll Med, Seoul, South Korea; Ewha Womans Univ, Dept Radiol, Seoul Hosp, Seoul, South Korea; Pusan Natl Univ, Sch Med, Dept Radiol, Pusan Natl Univ Hosp, Busan, South Korea; Biomed Res Inst, Busan, South Korea | ; Park, Chang/J-8409-2016; Yoon, Soon/AAL-1640-2020; Lee, Jung-Seok/L-6826-2019; Kim, Jin Young/AAB-6510-2020; Chung, Myung/C-1876-2011; Nam, Boda/MSX-2031-2025; Kim, Juhee/KFS-3069-2024; Yoo, Jin/AAG-6414-2019 | 57219956574; 35893853100; 57193992783; 57195310676; 57216496820; 57193577386; 57192422019; 55862597800; 55910532600; 59080545400; 7402897119; 55515341400; 57196009389; 55728272500; 56436943800; 57192908764; 57220153071; 57203597198; 57027170100; 16234023200; 35313444300; 57706214000 | jeongyj@pusan.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 46 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.88 | 2025-06-25 | 15 | 14 | Coronavirus Infections; Radiography; Thoracic; Computed Tomography | PNEUMONIA; COVID-19; DAEGU | Coronavirus Infections; Radiography, Thoracic; Computed Tomography | Adolescent; Adult; Aged; Aged, 80 and over; Child; Cohort Studies; COVID-19; Female; Humans; Male; Middle Aged; Radiography, Thoracic; Retrospective Studies; SARS-CoV-2; Tomography, X-Ray Computed; Young Adult; adolescent; adult; aged; child; cohort analysis; diagnostic imaging; female; human; male; middle aged; procedures; retrospective study; therapy; thorax radiography; very elderly; x-ray computed tomography; young adult | English | 2020 | 2020-11-30 | 10.3346/jkms.2020.35.e413 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | IgG Seroprevalence of COVID-19 among Individuals without a History of the Coronavirus Disease Infection in Daegu, Korea | Background: Seroprevalence studies of coronavirus disease 2019 (COVID-19) from many countries have shown that the number of undiagnosed missing cases is much larger than that of confirmed cases, irrespective of seroprevalence levels. Considering the strategy of Korea entailing massive testing and contact tracing from the beginning of epidemic, the number of undiagnosed missing cases in Korea may be negligible. This study was conducted to estimate the seroprevalence of COVID-19 among individuals who were never diagnosed with COVID-19 in Daegu, the epicenter of COVID-19 epidemic in Korea. Methods: Serologic testing for immunoglobulin G antibody based on immunochromatographic assay was conducted in 103 patients and 95 guardians aged 18 to 82 years without any history of COVID-19 diagnosis, who visited outpatient clinics of a single university-affiliated hospital from May 25 to June 5, 2020. Results: The estimated seroprevalence was 7.6% (95% confidence interval, 4.3%-12.2%) with 15 positive cases. Among them, only one had a polymerase chain reaction (PCR)-confirmed case among their close contacts and 13 did not experience COVID-19-related symptoms. Seroprevalence was similar between patients and guardians. Based on this figure, the number of undiagnosed missing cases in Daegu was estimated to be a dozen times more than the number of confirmed cases based on PCR testing. Conclusion: Despite the limitation of a small and unrepresentative sample, this is the first study on seroprevalence of COVID-19 in Korea. Our study suggested that the number of undiagnosed missing cases was substantial even with the stringent strategy adopted in Korea, similar to that of other countries. | Song, Suk-Kyoon; Lee, Duk-Hee; Nam, Jun-Ho; Kim, Kyung-Tae; Do, Jung-Suk; Kang, Dae-Won; Kim, Sang-Gyung; Cho, Myung-Rae | Daegu Catholic Univ Hosp, Dept Orthoped, 33 Duryugongwon Ro 17 Gil, Daegu 42472, South Korea; Kyungpook Natl Univ, Sch Med, Dept Prevent Med, Daegu, South Korea; Daegu Catholic Univ Hosp, Dept Lab Med, 33 Duryugongwon Ro 17 Gil, Daegu 42472, South Korea | ; Kim, Mi-Kyung/E-8682-2012 | 57215009048; 57211851121; 57219418315; 55710529400; 57204710869; 57216976291; 7601590190; 35145207900 | sgkim@cu.ac.kr;cmr0426@cu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 29 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 2.87 | 2025-06-25 | 37 | 39 | Antibody Test; COVID-19; Daegu; Hospital Visitors; Seroprevalence; Korea | Antibody Test; COVID-19; Daegu; Hospital Visitors; Korea; Seroprevalence | Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Antibodies, Viral; Betacoronavirus; Contact Tracing; Coronavirus Infections; Female; Humans; Immunoglobulin G; Male; Mass Screening; Middle Aged; Pandemics; Pneumonia, Viral; Polymerase Chain Reaction; Republic of Korea; Seroepidemiologic Studies; Serologic Tests; Surveys and Questionnaires; Undiagnosed Diseases; Young Adult; immunoglobulin G; virus antibody; adolescent; adult; aged; Betacoronavirus; blood; contact examination; Coronavirus infection; female; human; immunology; male; mass screening; middle aged; outpatient department; pandemic; polymerase chain reaction; procedures; questionnaire; seroepidemiology; serology; South Korea; very elderly; virology; virus pneumonia; young adult | English | 2020 | 2020-07-27 | 10.3346/jkms.2020.35.e269 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Impacts of Remaining Single above the Mean Marriage Age on Mental Disorders and Suicidality: a Nationwide Study in Korea | Background: This study investigated the impact of getting older than the mean marriage age on mental disorders and suicidality among never-married people. Methods: We performed an epidemiological survey, a nationwide study of mental disorders, in 2016. In this study, a multi-stage cluster sampling was adopted. The Korean version of the Composite International Diagnostic Interview was conducted with 5,102 respondents aged 18 years or above. The associations between never-married status, mental disorders, and suicidality were explored according to whether the mean age of first marriage (men = 32.8 years; women = 30.1 years) had passed. Results: Never-married status over the mean marriage age was associated with agoraphobia, obsessive-compulsive disorder, mood disorders, and major depressive disorder after adjusting for sociodemographic factors. Respondents with never-married status above the mean marriage age were associated with suicide attempts (adjusted odds ratio [aOR], 3.21; 95% confidence interval [CI], 1.36-7.60) after controlling for sociodemographic factors and lifetime prevalence of mental disorders, while respondents with never-married status under the mean marriage age were not. Moreover, in respondents with never-married status, getting older than the mean marriage age was associated with suicidal ideations (aOR, 1.49; 95% CI, 1.04-2.15) and suicide attempts (aOR, 3.38; 95% CI, 1.46-7.84) after controlling for sociodemographic factors and lifetime prevalence of mental disorders. Conclusion: Never-married status above the mean first marriage age was associated with mental disorders and suicidality. These findings suggest the need for a national strategy to develop an environment where people with never-married status do not suffer even if their marriage is delayed. | Lee, Jimin; Kim, Hyerim; Woo, Jungmin; Chang, Sung Man; Hong, Jin Pyo; Lee, Dong-Woo; Hahm, Bong-Jin; Cho, Seong-Jin; Park, Jong-Ik; Jeon, Hong Jin; Seong, Su Jeong; Park, Jee Eun; Kim, Byung-Soo | Kyungpook Natl Univ Hosp, Dept Psychiat, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Psychiat, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Sungkyunkwan Univ, Sch Med, Dept Psychiat, Seoul, South Korea; Inje Univ, Dept Psychiat, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Psychiat, Coll Med, Seoul, South Korea; Gachon Univ, Dept Psychiat, Coll Med, Incheon, South Korea; Kangwon Natl Univ, Dept Psychiat, Sch Med, Chunchon, South Korea; Kangdong Sacred Heart Hosp, Dept Psychiat, Seoul, South Korea; Kyungpook Natl Univ, Dept Psychiat, Chilgok Hosp, Daegu, South Korea | Lee, Dong/H-2427-2012; Kim, Byung-Soo/H-4047-2013; Hahm, Bong-Jin/J-5714-2012 | 57219156372; 57219156193; 56241307600; 23092756400; 55729426400; 56337476800; 6601908426; 55572091200; 15036290300; 35195917400; 55079714000; 56119414400; 57214661242 | because99@hanmail.net; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 37 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.64 | 2025-06-25 | 13 | 13 | Marriage; Single Person; Mental Disorders; Suicide; Cross-sectional Studies | GENERALIZED ANXIETY DISORDER; ALCOHOL-USE DISORDER; MARITAL-STATUS; RISK-FACTORS; GENDER DIFFERENCES; HEALTH BEHAVIORS; CO-MORBIDITY; PREVALENCE; DEPRESSION; LIFE | Cross-sectional Studies; Marriage; Mental Disorders; Single Person; Suicide | Adolescent; Adult; Aged; Cross-Sectional Studies; Humans; Interviews as Topic; Marriage; Mental Disorders; Middle Aged; Prevalence; Republic of Korea; Socioeconomic Factors; Suicide, Attempted; Surveys and Questionnaires; Young Adult; adolescent; adult; aged; cross-sectional study; human; interview; marriage; mental disease; middle aged; pathology; prevalence; questionnaire; socioeconomics; South Korea; suicide attempt; young adult | English | 2020 | 2020-09-21 | 10.3346/jkms.2020.35.e319 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Implantable Cardioverter-defibrillator Utilization and Its Outcomes in Korea: Data from Korean Acute Heart Failure Registry | Background: There are sparse data on the utilization rate of implantable cardioverterdefibrillator (ICD) and its beneficial effects in Korean patients with heart failure with reduced left ventricular ejection fraction (LVEF). Methods: Among 5,625 acute heart failure (AHF) patients from 10 tertiary university hospitals across Korea, 485 patients with reassessed LVEF <= 35% at least 3 months after the index admission were enrolled in this study. The ICD implantation during the follow-up was evaluated. Mortality was compared between patients with ICDs and age-, sex-, and follow-up duration matched control patients. Results: Among 485 patients potentially indicated for an ICD for primary prevention, only 56 patients (11.5%) underwent ICD implantation during the follow-up. Patients with ICD showed a significantly lower all-cause mortality compared with their matched control population: adjusted hazard ratio (HR) (95% confidence interval [CI]) = 0.39 (0.16-0.92), P = 0.032. The mortality rate was still lower in the ICD group after excluding patients with cardiac resynchronization therapy (adjusted HR [95% CI] = 0.09 [0.01-0.63], P = 0.015). According to the subgroup analysis for ischemic heart failure, there was a significantly lower all-cause mortality in the ICD group than in the no-ICD group (HR [95% CI] = 0.20 [0.06- 0.72], P = 0.013), with a borderline statistical significance (interaction P = 0.069). Conclusion: Follow-up data of this large, multicenter registry suggests a significant under utilization of ICD in Korean heart failure patients with reduced LVEF. Survival analysis implies that previously proven survival benefit of ICD in clinical trials could be extrapolated to Korean patients. | Cho, Youngjin; Cho, Sang-Yeong; Oh, Il-Young; Lee, Ji Hyun; Park, Jin Joo; Lee, Hae-Young; Kim, Kye Hun; Yoo, Byung-Su; Kang, Seok-Min; Baek, Sang Hong; Jeon, Eun-Seok; Kim, Jae-Joong; Cho, Myeong-Chan; Chae, Shung Chull; Oh, Byung-Hee; Choi, Dong-Ju | Seoul Natl Univ Bundang Hosp, Dept Internal Med, Seongnam, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Chonnam Natl Univ, Dept Internal Med, Heart Res Ctr, Gwangju, South Korea; Yonsei Univ, Dept Internal Med, Wonju Coll Med, Wonju, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Catholic Univ Korea, Dept Internal Med, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Dept Internal Med, Seoul, South Korea; Univ Ulsan, Dept Internal Med, Coll Med, Seoul, South Korea; Chungbuk Natl Univ, Dept Internal Med, Coll Med, Cheongju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea | ; Kim, Kyung-Hee/JBI-8300-2023; Oh, Il-Young/ACC-0418-2022; Oh, Byung-Hee/G-9875-2011; lee, wj/JNR-4926-2023; Jeong, Gi/AAB-2830-2021; Choi, Dong-Ju/J-5686-2012 | 56313472800; 57215306271; 8724022000; 57203144552; 35799900000; 56151235500; 56150430800; 7102851884; 7405685375; 7201371594; 7004279641; 36065764100; 7401727518; 7101962036; 57216293873; 35274349200 | djchoi@snubh.org; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 46 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.16 | 2025-06-25 | 3 | 3 | Implantable Cardioverter-defibrillator; Heart Failure | EJECTION FRACTION; MYOCARDIAL-INFARCTION; REGIONAL-VARIATIONS; CARVEDILOL; GUIDELINES; MORTALITY; SURVIVAL; BLOCKER | Heart Failure; Implantable Cardioverter-defibrillator | Aged; Defibrillators, Implantable; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Proportional Hazards Models; Registries; Republic of Korea; Survival Analysis; Tertiary Care Centers; Treatment Outcome; Ventricular Function, Left; aged; clinical trial; female; follow up; heart failure; heart left ventricle function; human; implantable cardioverter defibrillator; male; middle aged; mortality; physiology; proportional hazards model; register; South Korea; survival analysis; tertiary care center; treatment outcome | English | 2020 | 2020-11-30 | 10.3346/jkms.2020.35.e397 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Incremental Predictive Value of Plasma Renin Activity as a Prognostic Biomarker in Patients with Heart Failure | Background: The association of N-terminal pro-B type natriuretic peptide (NT-proBNP) and plasma renin activity (PRA) for the prognosis of the patients with acute heart failure (HF) has not been fully investigated. This study aimed to determine the association between NT-proBNP and PRA and to investigate the incremental value of PRA to NT-proBNP for predicting long term prognosis in patients with acute HF. Methods: Three hundred and ninety-six patients (mean age, 64.7 +/- 15.9 years; 46.5% female) presenting with acute HF were enrolled between December 2004 and July 2013. Patients with newly diagnosed HF as well as patients with acute exacerbated chronic HF were included. The prognosis was assessed with the composite event of all-cause mortality and readmission for HF during a 2-year follow-up period. Results: The etiology of HF was ischemic in 116 (29.3%) patients. In a Cox proportional hazards model, log-transformed PRA (hazard ratio [HR), 1.205; P= 0.007) was an independent predictor of the composite outcome of all-cause mortality and readmission for HF in addition to age (HR, 1.032; P= 0.001), white blood cell (WBC) count (HR, 1.103; P< 0.001), and left ventricular ejection fraction (LVEF) (HR, 0.978; P= 0.013). Adding PRA to age, sex, LVEF, and NT-proBNP significantly improved the prediction for the composite outcome ofall-cause mortality and readmission for HF, as shown by the net reclassification improvement (0.47; P< 0.001) and integrated discrimination improvement (0.10; P< 0.001). Conclusion: PRA could provide incremental predictive value to NT-proBNP for predicting long term prognosis in patients with acute HF. | Park, Bo Eun; Yang, Dong Heon; Kim, Hyeon Jeong; Park, Yoon Jung; Kim, Hong Nyun; Jang, Se Yong; Bae, Myung Hwan; Lee, Jang Hoon; Park, Hun Sik; Cho, Yongkeun; Chae, Shung Chull | Kyungpook Natl Univ Hosp, Dept Internal Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Cardiol Ctr, Daegu, South Korea | Park, Hang-soo/AEH-1640-2022 | 57201131446; 35277423400; 57204359002; 57216539556; 56706769800; 57207977889; 36607356800; 54581258000; 57198844106; 9249593500; 7101962036 | ddhyang@knu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 35 | 42 | SCIE | MEDICINE, GENERAL & INTERNAL | 2020 | 2.153 | 54.8 | 0.16 | 2025-06-25 | 4 | 3 | Renin; Heart Failure; Natriuretic Peptides; Prognosis | ANGIOTENSIN SYSTEM; ESSENTIAL-HYPERTENSION; HORMONE; ATTACK | Heart Failure; Natriuretic Peptides; Prognosis; Renin | Aged; Aged, 80 and over; Area Under Curve; Biomarkers; Female; Heart Failure; Humans; Kaplan-Meier Estimate; Leukocyte Count; Male; Middle Aged; Natriuretic Peptide, Brain; Patient Readmission; Peptide Fragments; Prognosis; Proportional Hazards Models; Renin; Retrospective Studies; ROC Curve; Ventricular Function, Left; biological marker; brain natriuretic peptide; peptide fragment; pro-brain natriuretic peptide (1-76); renin; aged; area under the curve; blood; female; heart failure; heart left ventricle function; hospital readmission; human; Kaplan Meier method; leukocyte count; male; middle aged; mortality; pathology; physiology; prognosis; proportional hazards model; receiver operating characteristic; retrospective study; very elderly | English | 2020 | 2020-11-02 | 10.3346/jkms.2020.35.e351 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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