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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Shadow extension for ray casting enhances volumetric visualization in real-time 4D-OCT | Progress in swept source laser technology and graphics processing unit (GPU) have led to the realization of real time four-dimensional optical coherence tomography (4D-OCT). Various rendering algorithms have been introduced for volumetric OCT leading to enhanced spatial comprehension. These algorithms still cannot provide sufficient visual realism. Shadowing is one of the advanced rendering techniques used to provide realistic spatial comprehension for objects in space. We developed and implemented a shadow extension for ray casting for real-time 4D-OCT, using both a swept source (SS)-OCT and spectral domain (SD)-OCT. Our technique builds upon previously developed ray casting techniques, adding an additional shadowing computation. The shadow extension for ray casting yields greater three-dimensionality of objects via self-shadowing, and also improves depth perception of objects. We imaged a beveled needle hovering over a flat surface and found that the positioning of a beveled needle can be accurately determined in relation to the environment. The shadowing algorithm was implemented using texture memory of the GPU, which realized video rendering rate. The complete processing pipeline requires 47 ms with a volume size of 1024 x 256 x 100, with a 100 kHz sweep rate SS-OCT. This new algorithm may enhance interactive surgical guidance during ophthalmic microsurgery. | Jeong, Hyeonseog; Kim, Hyung-Jin; Hyeon, Min Gyu; Kim, Pilun; Choi, Youngwoon; Kim, Beop-Min | Korea Univ, Dept Bioconvergence Engn, Anam Ro 145, Seoul 02481, South Korea; Korea Univ, Res Inst Hlth Sci, Anam Ro 145, Seoul 02481, South Korea; Korea Univ, Dept Bio Micro Syst Technol, Anam Ro 145, Seoul 02481, South Korea; Kyungpook Natl Univ, Biomed Engn Res, Gukchaebosang Ro 680, Daegu 41944, South Korea | 57208298948; 56849749600; 57103519500; 56967482800; 57196325597; 35229693300 | bmk515@korea.ac.kr; | OPTICS COMMUNICATIONS | OPT COMMUN | 0030-4018 | 1873-0310 | 460 | SCIE | OPTICS | 2020 | 2.31 | 51.0 | 0.16 | 2025-06-25 | 4 | 4 | Optical coherence tomography; Real time volume rendering; GPU accelerated; Advanced rendering | OPTICAL COHERENCE TOMOGRAPHY; GRAPHICS PROCESSING UNIT; NEEDLE TRACKING; MEGAHERTZ OCT; SURGERY | Advanced rendering; GPU accelerated; Optical coherence tomography; Real time volume rendering | Computer graphics equipment; Depth perception; Graphics processing unit; Needles; Pipeline processing systems; Program processors; Surgery; Textures; Tomography; Volume rendering; Advanced rendering; GPU-accelerated; Laser technologies; Real time; Rendering algorithms; Spectral domains; Surgical guidance; Volumetric visualization; Optical tomography | English | 2020 | 2020-04-01 | 10.1016/j.optcom.2020.125237 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Comparative assessment regarding antioxidative and nutrition potential of Moringa oleifera leaves by bacterial fermentation | Moringa is considered as a miraculous plant because of its outstanding health-promoting properties. Moringa leaves are used in various forms for various purposes owing to its potential against that purpose. This experiment was performed to utilize the hidden potential of Moringa leaves. The Moringa leaves were fermented by Bacillus subtilis KCTC 13,241 for 24, 48, 72 and 96 h to identify the best time duration of fermentation. The antioxidant potential of fermented Moringa leaves was estimated by measuring the total phenolic content (TPC), total isoflavones content (TIFC), DPPH and ABTS free radical scavenging activity and SOD-like activity. In addition to these parameters, the concentration of various total amino acids (TAA) and fatty acids were also determined. The best treatment was 48 h fermented Moringa leaves because of the best results in all measured parameters except in fatty acids concentration. The highest fatty acids concentration was recorded in 24 h fermented leaves. The results of 48 h fermented Moringa leaves regarding TAA, TPC, TIFC, DPPH and ABTS radical scavenging potential and SOD-like activity were 121.95 +/- 3.74 mg/g, 310.25 +/- 3.77 mu g GAE/g, 1083.38 +/- 5.92 mu g/g, 63.12 +/- 2.38%, 78.45 +/- 3.32%, and 34.55 +/- 1.05% respectively. The palmitic, stearic, oleic, linoleic and linolenic acid concentration in 24 h fermented Moringa leaves was 55.32 +/- 1.93, 56.02 +/- 2.12, 53.82 +/- 2.54, 55.95 +/- 1.62 and 56.41 +/- 1.43% respectively. In conclusion, the present results disclose that fermented Moringa leaves are the source of natural antioxidants and nutrients. | Ali, Muhammad Waqas; Ilays, Muhammad Zahaib; Saeed, Muhammad Tariq; Shin, Dong-Hyun | Univ Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands, England; Kyungpook Natl Univ, Sch Appl Biosci, Plant Resource Dev Lab, Daegu 41566, South Korea; Univ Agr Faisalabad, Fac Agr, Faisalabad 38000, Pakistan; Hazara Univ, Fac Sci, Dept Agr, Khyber Pakhtunkhwa 21300, Pakistan | ; Saeed, Muhammad/I-8592-2019; Ali, Muhammad/V-1019-2017 | 59849025200; 35092606700; 59635675600; 7403352903 | dhshin@knu.ac.kr; | JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE | J FOOD SCI TECH MYS | 0022-1155 | 0975-8402 | 57 | 3 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2020 | 2.701 | 51.4 | 0.4 | 2025-06-25 | 7 | 8 | Antioxidants; Moringa oleifera; Medicinal plant; Fermentation; Isoflavones | BACILLUS-SUBTILIS; IN-VITRO; PHENOLIC-COMPOUNDS; ACID; STRESS; CONSTITUENTS; EXTRACTION; FLAVONOIDS | Antioxidants; Fermentation; Isoflavones; Medicinal plant; Moringa oleifera | Antioxidants; Bacteriology; Fermentation; Flavonoids; Free radicals; Linoleic acid; Palmitic acid; Bacterial fermentations; Comparative assessment; Free radical scavenging activity; Isoflavones; Linoleic and linolenic acids; Medicinal plants; Moringa oleifera; Total phenolic content; Plants (botany) | English | 2020 | 2020-03 | 10.1007/s13197-019-04146-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Core-periphery segregation in evolving prisoner's dilemma networks | Dense cooperative networks are an essential element of social capital for prosperous societies. These networks enable individuals to overcome collective action dilemmas by enhancing trust. In many biological and social settings, network structures evolve endogenously as agents exit relationships and build newones. However, the interplay between game strategy and interaction structure by which evolutionary dynamics leads to self-organization of dense cooperative networks has not been understood. Our prisoner's dilemma experiments with exit and partner choice options show that core-periphery segregation of cooperators and defectors drives the emergence of cooperation. Cooperators' Quit-for-Tat and defectors' Roving strategy lead to a highly asymmetric core and periphery structure. Densely connected to each other at the core, cooperators successfully isolate defectors at the periphery and earn larger payoffs. | Sohn, Yunkyu; Choi, Jung-Kyoo; Ahn, T. K. | Waseda Univ, Sch Polit Sci & Econ, Shinjuku Ku, 1-6-1 Nishiwaseda, Tokyo 1698050, Japan; Kyungpook Natl Univ, Sch Econ & Trade, 1370 Sankyuk Dong, Daegu 702701, South Korea; Seoul Natl Univ, Dept Polit Sci & Int Relat, Gwanakro 1, Seoul 151746, South Korea | 56019816900; 27171100800; 29067471400 | tkahn@snu.ac.kr; | JOURNAL OF COMPLEX NETWORKS | J COMPLEX NETW | 2051-1310 | 2051-1329 | 8 | 1 | SCIE | MATHEMATICS, INTERDISCIPLINARY APPLICATIONS | 2020 | 2.011 | 51.4 | 0.56 | 2025-06-25 | 4 | 6 | economic experiment; dynamic network; evolution; core-periphery structure; quit-for-tat; roving | PROMOTE COOPERATION; SOCIAL NETWORKS; EVOLUTION; TOPOLOGY; MODEL | core-periphery structure; dynamic network; economic experiment; evolution; quit-for-Tat; roving | Biology; Game theory; Core peripheries; Dynamic network; Economic experiments; evolution; quit-for-Tat; roving; Defects | English | 2020 | 2020-02 | 10.1093/comnet/cnz021 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Correction | Core-periphery segregation in evolving prisoner's dilemma networks (vol , pg , ) | Sohn, Yunkyu; Choi, Jung-Kyoo; Ahn, T. K. | Waseda Univ, Sch Polit Sci & Econ, Shinjuku Ku, 1-6-1 Nishiwaseda, Tokyo 1698050, Japan; Kyungpook Natl Univ, Sch Econ & Trade, 1370 Sankyuk Dong, Daegu 702701, South Korea; Seoul Natl Univ, Dept Polit Sci & Int Relat, Gwanakro 1, Seoul 151746, South Korea | 56019816900; 27171100800; 29067471400 | tkahn@snu.ac.kr; | JOURNAL OF COMPLEX NETWORKS | J COMPLEX NETW | 2051-1310 | 2051-1329 | 8 | 5 | SCIE | MATHEMATICS, INTERDISCIPLINARY APPLICATIONS | 2020 | 2.011 | 51.4 | 0 | 2025-06-25 | 3 | 0 | English | 2020 | 2020-10-01 | 10.1093/comnet/cnz042 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | E-sensing, calibrated PSL, and improved ESR techniques discriminate irradiated fresh grapefruits and lemons | Grapefruit and lemon were exposed to phytosanitary irradiation doses of 0, 0.4, and 1 kGy, and then electronic-sensing screening of irradiation status and identification of radiation-induced ESR markers were conducted during 20 days storage. Codex standard photostimulated luminescence measurement (PSL1) was not a reliable indicator of irradiation status. Electronic tongue and electronic nose, however, showed potential as screening tools for discriminating irradiated fruits from non-irradiated counterparts based on principal component analysis of taste attributes and flavor patterns. Calibrated PSL approach clearly distinguished irradiated from non-irradiated samples based on the PSL ratio (PSL2/PSL1). Verification of irradiation status by electron spin resonance spectroscopy revealed clear paramagnetic centers from both irradiated fruits samples and ethanol-vacuum drying pretreatment improved radiation-induced ESR signal detection; not prominent enough in 0.4 kGy-irradiated commodities during 20 days of storage. Peel parts of both fruits showed high limonene which proportionally increased with irradiation doses (p < 0.05 kGy). | Jo, Yunhee; Ameer, Kashif; Chung, Namhyeok; Kang, Yoon-Han; Ahn, Dong U.; Kwon, Joong-Ho | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Hlth & Environm Inst Daegu, Hlth Res Dept, Daegu 42183, South Korea; PMAS Arid Agr Univ, Inst Food & Nutr Sci, Rawalpindi 46300, Pakistan; Gangneung Wonju Natl Univ, Dept Food Proc & Distribut, Wonju 26403, Gangwon Do, South Korea; Iowa State Univ, Dept Anim Sci, Ames, IA 50011 USA | Ameer, Kashif/H-5449-2019 | 56533194300; 57190066397; 56533286200; 57193838458; 55701286500; 36814712700 | jhkwon@knu.ac.kr; | JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE | J FOOD SCI TECH MYS | 0022-1155 | 0975-8402 | 57 | 1 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2020 | 2.701 | 51.4 | 0.32 | 2025-06-25 | 9 | 10 | Citrus; Phytosanitary irradiation; Detection; Electronic sensing; Volatiles | ELECTRONIC NOSE; VINEGARS; TONGUE | Citrus; Detection; Electronic sensing; Phytosanitary irradiation; Volatiles | Citrus fruits; Data handling; Electronic nose; Electronic tongues; Error detection; Irradiation; Magnetic moments; Principal component analysis; Radiation; Citrus; Electronic sensing; Irradiated samples; Paramagnetic centers; Photo stimulated luminescence; Phytosanitary; Radiation-induced; Volatiles; Electron spin resonance spectroscopy | English | 2020 | 2020-01 | 10.1007/s13197-019-04068-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Editorial Material;Article | Improving MapReduce scheduler for heterogeneous workloads in a heterogeneous environment | Big data is largely influencing business entities and research sectors to be more data-driven. Hadoop MapReduce is one of the cost-effective ways to process large scale datasets and offered as a service over the Internet. Even though cloud service providers promise an infinite amount of resources available on-demand, it is inevitable that some of the hired virtual resources for MapReduce are left unutilized and makespan is limited due to various heterogeneities that exist while offering MapReduce as a service. As MapReduce v2 allows users to define the size of containers for the map and reduce tasks, jobs in a batch become heterogeneous and behave differently. Also, the different capacity of virtual machines in the MapReduce virtual cluster accommodate a varying number of map/reduce tasks. These factors highly affect resource utilization in the virtual cluster and the makespan for a batch of MapReduce jobs. Default MapReduce job schedulers do not consider these heterogeneities that exist in a cloud environment. Moreover, virtual machines in MapReduce virtual cluster process an equal number of blocks regardless of their capacity, which affects the makespan. Therefore, we devised a heuristic-based MapReduce job scheduler that exploits virtual machine and MapReduce workload level heterogeneities to improve resource utilization and makespan. We proposed two methods to achieve this: (i) roulette wheel scheme based data block placement in heterogeneous virtual machines, and (ii) a constrained 2-dimensional bin packing to place heterogeneous map/reduce tasks. We compared heuristic-based MapReduce job scheduler against the classical fair scheduler in MapReduce v2. Experimental results showed that our proposed scheduler improved makespan and resource utilization by 45.6% and 47.9% over classical fair scheduler. | Jeyaraj, Rathinaraja; Ananthanarayana, V. S.; Paul, Anand | Natl Inst Technol Karnataka, Dept IT, Mangalore, India; Kyungpook Natl Univ, Sch Comp Sci & Engn, 80 Daehakro, Daegu 702701, South Korea | S, A/AAE-2005-2020; Jeyaraj, Rathinaraja/ABB-7781-2021; Paul, Anand/V-6724-2017 | 57203111601; 23396223700; 56650522400 | paul.editor@gmail.com; | CONCURRENCY AND COMPUTATION-PRACTICE & EXPERIENCE | CONCURR COMP-PRACT E | 1532-0626 | 1532-0634 | 32 | 17 | SCIE | COMPUTER SCIENCE, SOFTWARE ENGINEERING;COMPUTER SCIENCE, THEORY & METHODS | 2020 | 1.536 | 51.4 | 0.6 | 2025-06-25 | 0 | 11 | bin packing; heterogeneous workloads/jobs; map/reduce task placement | DATA PLACEMENT; BIG DATA; PERFORMANCE | bin packing; heterogeneous workloads/jobs; map/reduce task placement | Cloud computing; Cost effectiveness; Large dataset; Network security; Scheduling; Virtual machine; Bin packing; Cloud environments; Cloud service providers; Heterogeneous environments; Heterogeneous workloads; Large-scale datasets; Map/reduce; Resource utilizations; Job shop scheduling | English | 2020 | 2020-09-10 | 10.1002/cpe.5558 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Mathematical Model of COVID-19 Transmission Dynamics in South Korea: The Impacts of Travel Restrictions, Social Distancing, and Early Detection | The novel coronavirus disease (COVID-19) poses a severe threat to public health officials all around the world. The early COVID-19 outbreak in South Korea displayed significant spatial heterogeneity. The number of confirmed cases increased rapidly in the Daegu and Gyeongbuk (epicenter), whereas the spread was much slower in the rest of Korea. A two-patch mathematical model with a mobility matrix is developed to capture this significant spatial heterogeneity of COVID-19 outbreaks from 18 February to 24 March 2020. The mobility matrix is taken from the movement data provided by the Korea Transport Institute (KOTI). Some of the essential patch-specific parameters are estimated through cumulative confirmed cases, including the transmission rates and the basic reproduction numbers (local and global). Our simulations show that travel restrictions between the epicenter and the rest of Korea effectively prevented massive outbreaks in the rest of Korea. Furthermore, we explore the effectiveness of several additional strategies for the mitigation and suppression of Covid-19 spread in Korea, such as implementing social distancing and early diagnostic interventions. | Kim, Byul Nim; Kim, Eunjung; Lee, Sunmi; Oh, Chunyoung | Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Korea Inst Sci & Technol, Nat Prod Informat Res Ctr, Kangnung 25451, South Korea; Kyung Hee Univ, Dept Appl Math, Yongin 17104, South Korea; Chonnam Natl Univ, Dept Math Educ, Gwangju 61186, South Korea | 24281456900; 55964356400; 55716483800; 56236882400 | air1227@gmail.com;eunjung.kim@kist.re.kr;sunmilee@khu.ac.kr;cyoh@jnu.ac.kr; | PROCESSES | PROCESSES | 2227-9717 | 8 | 10 | SCIE | ENGINEERING, CHEMICAL | 2020 | 2.847 | 51.4 | 1.32 | 2025-06-25 | 19 | 26 | COVID-19 transmission dynamics in South Korea; two-patch mathematical model; mobility data; basic reproduction number; cumulative incidence; travel restrictions; social distancing; early diagnostic interventions | INTERVENTIONS | Basic reproduction number; COVID-19 transmission dynamics in South Korea; Cumulative incidence; Early diagnostic interventions; Mobility data; Social distancing; Travel restrictions; Two-patch mathematical model | English | 2020 | 2020-10 | 10.3390/pr8101304 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Chronic Infiltration of T Lymphocytes into the Brain in a Non-human Primate Model of Parkinson's Disease | Study of interactions between the nervous system and immunity offers insights into the pathogenesis of Parkinson's disease (PD) and potential therapeutic strategies for neurodegenerative diseases. Studies on rodents have revealed regulatory mechanisms of microglial activation and T lymphocyte recruitment in PD. However, the mechanisms underlying chronic T lymphocyte infiltration into the brain after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) injection into a non-human primate (NHP) model of PD remain unknown. This study aimed to investigate changes in serum RANTES (regulated on activation, normal T cell expression and secretion) and analyze the chronic infiltration of T lymphocytes into the brain and microglia activation in NHPs at 48 weeks post-MPTP administration. We found selective and local chronic infiltration of CD4+ and CD8+ T lymphocytes, loss of dopaminergic neurons, dopamine transporter expression, chronic normalization of RANTES in the peripheral blood, and altered microglial morphology at 48 weeks after MPTP injection. This study confirms the involvement of CD4+ and CD8+ T lymphocyte infiltration in MPTP-induced NHP models of PD. Additionally, we corroborated previous findings regarding the mechanisms of T lymphocyte-induced neurodegeneration. The findings of chronic infiltration of T lymphocytes in our NHP model of PD provide novel insights into PD pathogenesis and the development of preventive and therapeutic agents. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of IBRO. | Seo, Jincheol; Park, Junghyung; Kim, Keonwoo; Won, Jinyoung; Yeo, Hyeon-Gu; Jin, Yeung Bae; Koo, Bon-Sang; Lim, Kyung Seob; Jeong, Kang-Jin; Kang, Philyong; Lee, Hwal-Yong; Choi, Won Seok; Baek, Seung Ho; Jeon, Chang-Yeop; Hong, Jung-Joo; Huh, Jae-Won; Kim, Young-Hyun; Park, Sang Je; Kim, Sun-Uk; Lee, Dong-Seok; Lee, Sang-Rae; Lee, Youngjeon | Korea Res Inst Biosci & Biotechnol, Natl Primate Res Ctr, Cheongju 28116, South Korea; Kyungpook Natl Univ, Sch Life Sci, BK21 Plus KNU Creat BioRes Grp, Daegu 41566, South Korea; Korea Univ Sci & Technol, KRIBB Sch Biosci, Dept Funct Genom, Daejeon 34113, South Korea; KRIBB, Futurist Anim Resource & Res Ctr, Cheongju 28116, South Korea | Kim, Junghwan/AAV-1973-2020; Koo, Bon-Sang/AAT-6063-2021; Kim, Sunuk/KJM-5211-2024; 김, 영현/HLH-3847-2023; Park, Junghyung/KXQ-7522-2024; Lee, Youngjeon/LZH-8969-2025 | 57200518242; 55671747100; 57204572034; 56018670200; 56263762800; 35344928700; 57204576307; 36470521900; 56181213100; 56720870900; 57204156780; 57215086073; 57207138619; 56522472100; 36808240600; 16645802900; 54393408600; 24348800900; 8278891100; 57210068061; 16026266200; 57199022088 | neurosci@kribb.re.kr; | NEUROSCIENCE | NEUROSCIENCE | 0306-4522 | 1873-7544 | 431 | SCIE | NEUROSCIENCES | 2020 | 3.59 | 51.5 | 1.25 | 2025-06-25 | 24 | 23 | Parkinson's disease; MPTP; non-human primate; T-cell; RANTES; dopamine transporter | PERIPHERAL-BLOOD LYMPHOCYTES; MPTP MOUSE MODEL; INTRACEREBROVENTRICULAR INJECTION; MICROGLIAL ACTIVATION; ADAPTIVE IMMUNITY; TEMPLATE ATLAS; MONKEY MODEL; DOPAMINE; CELLS; NEURODEGENERATION | dopamine transporter; MPTP; non-human primate; Parkinson's disease; RANTES; T-cell | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Parkinson Disease; Primates; 1,2,3,6 tetrahydro 1 methyl 4 phenylpyridine; dopamine transporter; RANTES; adult; animal cell; animal experiment; animal model; animal tissue; Article; blood sampling; brain function; CD4+ T lymphocyte; CD8+ T lymphocyte; cell activation; cell structure; controlled study; dopaminergic nerve cell; female; lymphocytic infiltration; Macaca fascicularis; microglia; nerve degeneration; nonhuman; Parkinson disease; pathogenesis; priority journal; protein expression; animal; brain; C57BL mouse; disease model; mouse; primate | English | 2020 | 2020-04-01 | 10.1016/j.neuroscience.2020.01.043 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Letter | Treatment outcomes of patients with salivary duct carcinoma undergoing surgery and postoperative radiotherapy | Lee, Dong Soo; Lee, Chang Geol; Keum, Ki Chang; Chung, Seung Yeun; Kim, Taehyung; Wu, Hong-Gyun; Kim, Jin Ho; Sung, Myung-Whun; Ahn, Soon-Hyun; Cho, Kwan Ho; Kang, Ki Mun; Oh, Young-Taek; Kim, Jin Hee; Kang, Min Kyu | Catholic Univ Korea, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Yonsei Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Radiat Oncol, Seoul, South Korea; Seoul Natl Univ, Coll Med, Canc Res Inst, Seoul, South Korea; Seoul Natl Univ, Med Res Ctr, Inst Radiat Med, Seoul, South Korea; Seoul Natl Univ, Coll Med, Dept Otorhinolaryngol Head & Neck Surg, Seoul, South Korea; Natl Canc Ctr, Res Inst & Hosp, Proton Therapy Ctr, Goyang, South Korea; Gyeongsang Natl Univ, Sch Med, Dept Radiat Oncol, Jinju, South Korea; Gyeongsang Natl Univ, Changwon Hosp, Jinju, South Korea; Ajou Univ, Sch Med, Dept Radiat Oncol, Suwon, South Korea; Keimyung Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiat Oncol, Daegu, South Korea | Lee, Chang/HME-1129-2023; KANG, MIN KYU/ACI-8824-2022; Kang, Kimun/AAA-3684-2022; Kim, Kunhong/C-1304-2008; Cho, Hwa Jin/AFA-1420-2022; Ahn, Soon-Hyun/J-5528-2012; Kim, Juhee/KFS-3069-2024; Wu, Hong/J-5547-2012 | 57811935400; 7410147639; 6602364397; 57194017690; 55763792349; 7405583405; 56723658800; 7202291312; 35721449100; 56507757300; 13003101000; 56812468700; 56441016600; 57201933342 | cglee1023@yuhs.ac;mkkang@knu.ac.kr; | ACTA ONCOLOGICA | ACTA ONCOL | 0284-186X | 1651-226X | 59 | 5 | SCIE | ONCOLOGY | 2020 | 4.089 | 51.5 | 0.73 | 2025-06-25 | 5 | 5 | GLAND CANCERS | Adult; Aged; Carcinoma; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Radiotherapy, Adjuvant; Republic of Korea; Retrospective Studies; Salivary Ducts; Salivary Gland Neoplasms; Young Adult; antineoplastic agent; adjuvant chemotherapy; adult; aged; cancer control; cancer patient; cancer prognosis; cancer radiotherapy; cancer surgery; cancer survival; clinical article; controlled study; disease free survival; female; human; Letter; lymph node metastasis; male; neck dissection; overall survival; parotid gland cancer; parotidectomy; postoperative care; priority journal; salivary duct carcinoma; salivary gland carcinoma; treatment failure; treatment outcome; wide excision; adjuvant radiotherapy; carcinoma; clinical trial; epidemiology; follow up; Kaplan Meier method; middle aged; mortality; multicenter study; pathology; radiation response; retrospective study; salivary gland duct; salivary gland tumor; South Korea; surgery; young adult | English | 2020 | 2020-05-03 | 10.1080/0284186x.2020.1730005 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Fuel poverty and rebound effect in South Korea: An estimation for home appliances using the modified regression model | Since the occurrence of oil shocks in the 1970s, a number of countries have introduced fuel poverty programs. However, rebound effects could be problematic even in these programs. In particular, there are two controversies surrounding rebound effects: the magnitude of rebound effects and the influence of income on these effects. This study attempts to resolve these issues by empirically estimating the rebound effects of individual home appliances for low-income households. Thereafter, it compares the rebound effects for low-income families with those for all-income families. Analyses results suggest that the magnitude of rebound effects highly depends on individual home appliances, and that these effects are usually larger for low-income households. Thus, the differences in rebound effects between all-income and low-income households also depend on individual appliances. Therefore, policy-makers should meticulously consider the rebound effects of individual home appliances when planning energy efficiency programs. | Jin, Sang-Hyeon | Kyungpook Natl Univ, Sch Publ Adm, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Publ Affairs, 80 Daehakro, Daegu 41566, South Korea | Jin, Sang-Hyeon/AFU-7621-2022 | 55587091300 | upperhm@knu.ac.kr; | ENERGY & ENVIRONMENT | ENERG ENVIRON-UK | 0958-305X | 2048-4070 | 31 | 7 | SSCI | ENVIRONMENTAL STUDIES | 2020 | 2.945 | 51.6 | 0.23 | 2025-06-25 | 5 | 5 | Fuel poverty; rebound effect; backfire effect; direct estimation; concavity; super conservation | LOW-INCOME HOUSEHOLDS; ENERGY EFFICIENCY; EMPIRICAL-EVIDENCE; THERMAL COMFORT; CONSUMPTION; POLICY; IMPACT; RESIDENTS; RETROFIT; BEHAVIOR | backfire effect; concavity; direct estimation; Fuel poverty; rebound effect; super conservation | South Korea; Domestic appliances; Energy efficiency; Fuels; Regression analysis; backfire effect; concavity; Energy efficiency programs; Fuel poverty; Policy makers; Rebound effect; Regression model; South Korea; energy efficiency; energy planning; energy policy; energy resource; fuel consumption; household income; low income population; policy making; Economic analysis | English | 2020 | 2020-11 | 10.1177/0958305x19877529 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Detrimental effects of temephos on male fertility: An in vitro study on a mouse model | The World Health Organization recommends temephos as a nonsystemic organophosphorus pesticide due to its low mammalian toxicity compared with other chemical compounds. Although several studies have reported that temephos may be toxic under certain conditions, little research effort has been made to evaluate its effects on mammalian fertility. Therefore, the present study was designed to evaluate the effect of temephos on sperm functions and male fertility. Initially, cauda epididymis from mouse spermatozoa was incubated with temephos (0, 0.1, 1, 10, and 100 mu M). Then, sperm motility and motion kinematics, capacitation status, intracellular adenosine triphosphate level, lactate dehydrogenase level, protein kinase A (PKA) activity, and degree of tyrosine phosphorylation were analyzed. Finally, the rates of fertilization and early embryonic development were evaluated. Sperm motility and motion kinematics were found to be significantly altered in temephos groups. In addition, the acrosome reaction and capacitation significantly increased and decreased in the 100 mu M temephos group, respectively. Intracellular adenosine triphosphate levels significantly decreased in the 1, 10, and 100 mu M temephos groups compared with that in the control group. Moreover, PKA activity and tyrosine phosphorylation significantly decreased in most temephos groups. Further, the rates of fertilization and early embryonic development significantly decreased in all temephos groups. Taken together, it was determined that temephos had harmful effects on male fertility. Therefore, the reproductive toxicity of temephos should be considered before its use. | Kim, So-Hye; Bae, Jeong-Won; Kim, Dae-Hyun; Jeong, Dae-Jin; Ha, Jae Jung; Yi, Jun Koo; Kwon, Woo-Sung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea; Gyeongbuk Livestock Res Inst, Yeongju 36052, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Dept Anim Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea | ; Kwon, Woo-Sung/J-4391-2014; Bae, Jeong-Won/AAH-4932-2021; Kwon, Woo-Sung/J-6731-2019; Yi, Junkoo/JBR-8507-2023 | 57211230697; 57211231093; 57211228843; 57220792015; 55848402300; 56182537200; 54383715800 | wskwon@knu.ac.kr; | REPRODUCTIVE TOXICOLOGY | REPROD TOXICOL | 0890-6238 | 96 | SCIE | REPRODUCTIVE BIOLOGY;TOXICOLOGY | 2020 | 3.143 | 51.7 | 0.86 | 2025-06-25 | 16 | 17 | Temephos; Spermatozoa; Fertilization; Male fertility; Reproductive toxicity | SPERM MOTILITY; INSECTICIDES; RESISTANCE | Fertilization; Male fertility; Reproductive toxicity; Spermatozoa; Temephos | Adenosine Triphosphate; Animals; Embryonic Development; Female; Fertility; Insecticides; L-Lactate Dehydrogenase; Male; Mice, Inbred ICR; Models, Animal; Sperm Capacitation; Sperm Motility; Spermatozoa; Temefos; adenosine triphosphate; cyclic AMP dependent protein kinase; lactate dehydrogenase; temefos; adenosine triphosphate; insecticide; lactate dehydrogenase; temefos; acrosome reaction; animal cell; animal experiment; animal model; Article; blastocyst; cauda epididymis; controlled study; embryo development; enzyme activity; epididymis; fertilization; in vitro fertilization; in vitro study; lactate dehydrogenase blood level; male; male genital tract parameters; male infertility; motion kinematics; mouse; mouse model; nonhuman; protein phosphorylation; reproductive toxicity; spermatozoon; spermatozoon capacitation; spermatozoon motility; animal; drug effect; female; fertility; Institute for Cancer Research mouse; metabolism; physiology; sperm capacitation | English | 2020 | 2020-09 | 10.1016/j.reprotox.2020.06.008 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Inhalation of ammonium sulfate and ammonium nitrate adversely affect sperm function | Among the components of air pollution in developing countries and Asia, (NH4)(2)SO4 and NH4NO3 are known as major water-soluble in-organic compounds that cause particulate matter. Several researchers have been reported that the (NH4)(2)SO4 and NH4NO3 induce abnormal decreases in body weight, as well as pneumotoxic, and immunotoxic. Moreover, while it has been reported that (NH4)(2)SO4 and NH4NO3 have detrimental effects on reproduction, specific effects on male fertility have not been addressed in depth. Therefore, the present study evaluated the reproductive toxicity of (NH4)(2)SO4 and NH4NO3 in spermatozoa under the capacitation condition. Results showed that various sperm motion parameters were significantly altered after inhalation of (NH4)(2)SO4 and NH4NO3. In particular, alterations to a range of motion kinematic parameters and to capacitation status were observed after capacitation. In addition, protein kinase A (PKA) activity and tyrosine phosphorylation were altered by (NH4)(2)SO4 and NH4NO3 regardless of capacitation. Taken together, our results show that inhalation of (NH4)(2)SO4 and NH4NO3 may induce adverse effects on male fertility such as sperm motility, motion kinematics, and capacitation status via unusual tyrosine phosphorylation by abnormal PKA activity. Therefore, we suggest that exposure to (NH4)(2)SO4 and NH4NO3 should be highlighted as a health risk, as it may lead to male reproductive toxicity in humans and animals. | Bae, Jeong-Won; Kwon, Hong Ju; Kim, So-Hye; Ma, Lei; Im, Hobin; Kim, Eungyung; Kim, Myoung Ok; Kwon, Woo-Sung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Dept Anim Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea | Bae, Jeong-Won/AAH-4932-2021; Kwon, Woo-Sung/J-6731-2019 | 57211231093; 57217867533; 57211230697; 57217867673; 57217867362; 57217871658; 8934745900; 54383715800 | ok4325@knu.ac.kr;wskwon@knu.ac.kr; | REPRODUCTIVE TOXICOLOGY | REPROD TOXICOL | 0890-6238 | 96 | SCIE | REPRODUCTIVE BIOLOGY;TOXICOLOGY | 2020 | 3.143 | 51.7 | 0.52 | 2025-06-25 | 11 | 11 | Ammonium sulfate; Ammonium nitrate; Sperm motility; Capacitation status; Protein kinase A; Tyrosine phosphorylation | TYROSINE PHOSPHORYLATION; CHEMICAL-CHARACTERIZATION; PERSULFATE; TOXICITY; AEROSOL; PM2.5; PERIODS; PM10 | Ammonium nitrate; Ammonium sulfate; Capacitation status; Protein kinase A; Sperm motility; Tyrosine phosphorylation | Administration, Inhalation; Air Pollutants; Ammonium Sulfate; Animals; Cyclic AMP-Dependent Protein Kinases; Male; Mice, Inbred C57BL; Nitrates; Phosphorylation; Sperm Capacitation; Sperm Motility; Spermatozoa; Tyrosine; ammonium nitrate; ammonium sulfate; cyclic AMP dependent protein kinase; ammonium nitrate; ammonium sulfate; cyclic AMP dependent protein kinase; nitric acid derivative; tyrosine; animal experiment; animal model; Article; C57BL/6N mouse; controlled study; enzyme activity; enzyme substrate; kinematics; male; male fertility; male genital tract parameters; mouse; nonhuman; particulate matter; protein phosphorylation; range of motion; reproductive toxicity; semen analysis; sperm motion; spermatozoon capacitation; spermatozoon motility; air pollutant; animal; C57BL mouse; drug effect; inhalational drug administration; metabolism; phosphorylation; physiology; sperm capacitation; spermatozoon; toxicity | English | 2020 | 2020-09 | 10.1016/j.reprotox.2020.08.009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Investigating the effects of fipronil on male fertility: Insight into the mechanism of capacitation | Fipronil (FPN) is a widely used phenylpyrazole pesticide for the control of insects and removal of veterinary pet fleas, ticks, etc. Although FPN presents moderate hazards to human health, people are readily exposed in daily life. FPN acts by impairing the central nervous systems of insects by blocking gamma-aminobutyric acid (GABA) and glutamate-activated chloride channels. A previous study demonstrated that GABA and GABA(A)R are present in spermatozoa and play various roles in the process of sperm capacitation, which is required for fertilization. However, the effects of FPN on mammalian fertility are not yet fully understood. Therefore, the present study was designed to investigate the effects of FPN on spermatozoa. Herein, we treated various concentrations of FPN (0.1, 1, 10, 100, and 300 mu M) or a control treatment with mouse spermatozoa. FPN treatment significantly reduced sperm motility, motion kinematic parameters, and intracellular ATP level, whereas the acrosome reaction was enhanced. Levels of phospho-PKA and phospho-tyrosine substrate were significantly decreased in a dose-dependent manner. Meanwhile, there was no difference between control and treatment groups in the level of GABA(A)R beta-3. Only the ratio of GABA(A)R beta-3 pS408/pS409 was significantly decreased at higher concentrations of FPN. Moreover, cleavage and blastocyst formation rates were also significantly decreased by FPN treatments. Taken together, these data suggest that FPN can directly and indirectly suppress various sperm functions. Therefore, FPN can negatively affect male fertility leading to infertility. From these results, we suggest that the use of FPN as a pesticide requires the attention of reproductive toxicity. | Bae, Jeong-Won; Kwon, Woo-Sung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Dept Anim Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea | ; Kwon, Woo-Sung/J-6731-2019; Kwon, Woo-Sung/J-4391-2014; Bae, Jeong-Won/AAH-4932-2021 | 57211231093; 54383715800 | wskwon@knu.ac.kr; | REPRODUCTIVE TOXICOLOGY | REPROD TOXICOL | 0890-6238 | 94 | SCIE | REPRODUCTIVE BIOLOGY;TOXICOLOGY | 2020 | 3.143 | 51.7 | 1.3 | 2025-06-25 | 21 | 22 | Fipronil; GABA(A) receptor; Spermatozoa; Capacitation; Male fertility | AMINOBUTYRIC-ACID GABA; ACROSOME REACTION; RECEPTORS; SPERM; CHANNELS | Capacitation; Fipronil; GABA<sub>A</sub> receptor; Male fertility; Spermatozoa | Adenosine Triphosphate; Animals; Female; Fertility; Insecticides; L-Lactate Dehydrogenase; Male; Mice, Inbred ICR; Pyrazoles; Sperm Capacitation; Sperm Motility; Spermatozoa; 4 aminobutyric acid A receptor beta3; adenosine triphosphate; fipronil; adenosine triphosphate; fipronil; insecticide; lactate dehydrogenase; pyrazole derivative; animal cell; Article; blastocyst; controlled study; dose response; female; kinematics; male; male fertility; mouse; nonhuman; protein cleavage; protein phosphorylation; reproductive toxicity; spermatozoon; spermatozoon capacitation; spermatozoon motility; toxic concentration; animal; drug effect; fertility; Institute for Cancer Research mouse; metabolism; physiology; sperm capacitation | English | 2020 | 2020-06 | 10.1016/j.reprotox.2020.04.002 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Quercetin-induced yeast apoptosis through mitochondrial dysfunction under the accumulation of magnesium in Candida albicans | Latterly, the upsurge in use of antifungal drugs has brought about the emergence of several drugresistance strains, making it skeptical to continue relying on current therapeutic regime. In the necessity of resistance-free antifungal agent, flavonoids presented possibilities of replacing existing drugs, displaying antifungal activity against pathogenic fungi. Among them, quercetin, one of the most representative flavonoids, exhibited antifungal activity against Candida albicans. To inspect the further understanding regarding quercetin, the antifungal mode of action of quercetin was investigated. In the initial step, the apoptosis was monitored after quercetin treatment. Moreover, intracellular levels of Mg2+ was assessed and was determined that Mg2+ increase occurred under the influence of quercetin. In addition, several features of mitochondrial dysfunction were monitored. Mitochondrial dysfunction triggers decrease in mitochondrial redox levels and leads to disruption in mitochondrial antioxidant system. Increased intracellular ROS and decreased intracellular redox levels were also displayed, indicating the occurrence of overall disruption in antioxidant systems. Sequentially, DNA fragmentation was observed and this DNA damage in turn induces apoptosis. In analyses, hexaamminecobalt(Ill) chloride (Cohex) was applied to inhibit Mg2+ transport between cytosol and mitochondria. Cohex attenuated the effects induced by quercetin, which demonstrates that the presence of Mg2+ is essential in quercetin-induced apoptosis. (C) 2019 Published by Elsevier Ltd on behalf of British Mycological Society. | Kwun, Min Seok; Lee, Dong Gun | Kyungpook Natl Univ, Sch Life Sci, BK21 Plus KNU Creat BioRes Grp, Daegu 41566, South Korea | Lee, Dong-Gun/IWD-9833-2023 | 57212491555; 55668060900 | dglee222@knu.ac.kr; | FUNGAL BIOLOGY | FUNGAL BIOL-UK | 1878-6146 | 1878-6162 | 124 | 2 | SCIE | MYCOLOGY | 2020 | 3.099 | 51.7 | 2.45 | 2025-06-25 | 39 | 41 | Cohex; Fungi; Flavonoid; Ion Accumulation; Programmed Cell Death | OXIDATIVE STRESS RESISTANCE; CALCIUM; GLUTATHIONE; ANTIFUNGAL; METABOLISM; FLAVONOIDS; INCREASES; TRANSPORT; RESPONSES; SYSTEM | Cohex; Flavonoid; Fungi; Ion Accumulation; Programmed Cell Death | Antifungal Agents; Antioxidants; Apoptosis; Candida albicans; Drug Resistance, Fungal; Magnesium; Mitochondria; Quercetin; Reactive Oxygen Species; Candida albicans; Fungi; antifungal agent; antioxidant; magnesium; quercetin; reactive oxygen metabolite; antioxidant; apoptosis; chloride; fungicide; magnesium; mitochondrion; pesticide resistance; reactive oxygen species; secondary metabolite; sodium chloride; yeast; antifungal resistance; apoptosis; Candida albicans; drug effect; metabolism; mitochondrion | English | 2020 | 2020-02 | 10.1016/j.funbio.2019.11.009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Vanadium adversely affects sperm motility and capacitation status via protein kinase A activity and tyrosine phosphorylation | Vanadium is a chemical element that enters the atmosphere via anthropogenic pollution. Exposure to vanadium affects cancer development and can result in toxic effects. Multiple studies have focused on vanadium's detrimental effect on male reproduction using conventional sperm analysis techniques. This study focused on vanadium's effect on spermatozoa following capacitation at the molecular level, in order to provide a more detailed assessment of vanadium's reproductive toxicity. We observed a decrease in germ cell density and a structural collapse of the testicular organ in seminiferous tubules during vanadium treatment. In addition, various sperm motion parameters were significantly decreased regardless of capacitation status, including sperm motility, rapid sperm motility, and progressive sperm motility. Curvilinear velocity, straight-line velocity, average path velocity, beat cross frequency, and mean amplitude of head lateral displacement were also decreased after capacitation. Capacitation status was altered after capacitation. Vanadium dramatically enhanced protein kinase A (PKA) activity and tyrosine phosphorylation. Taken together, our results suggest that vanadium is detrimental to male fertility by negatively influencing sperm motility, motion kinematics, and capacitation status via abnormal PKA activity and tyrosine phosphorylation before and after capacitation. | Bae, Jeong-Won; Im, Hobin; Hwang, Ju-Mi; Kim, So-Hye; Ma, Lei; Kwon, Hong Ju; Kim, Eungyung; Kim, Myoung Ok; Kwon, Woo-Sung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Dept Anim Biotechnol, Sangju 37224, Gyeongsangbuk D, South Korea | ; Bae, Jeong-Won/AAH-4932-2021; Kwon, Woo-Sung/J-4391-2014; Kwon, Woo-Sung/J-6731-2019 | 57211231093; 57217867362; 57217871526; 57211230697; 57217867673; 57217867533; 57217871658; 8934745900; 54383715800 | ok4325@knu.ac.kr;wskwon@knu.ac.kr; | REPRODUCTIVE TOXICOLOGY | REPROD TOXICOL | 0890-6238 | 1873-1708 | 96 | SCIE | REPRODUCTIVE BIOLOGY;TOXICOLOGY | 2020 | 3.143 | 51.7 | 0.52 | 2025-06-25 | 13 | 13 | Vanadium; Sperm motility; Capacitation status; Protein kinase A; Tyrosine phosphorylation | AIR-POLLUTION; MOUSE SPERM; DNA-DAMAGE; PENTOXIDE; DISEASE; KIDNEY; RATS; HYPERACTIVATION; PENETRATION; PARAMETERS | Capacitation status; Protein kinase A; Sperm motility; Tyrosine phosphorylation; Vanadium | Animals; Cyclic AMP-Dependent Protein Kinases; Male; Mice, Inbred BALB C; Phosphorylation; Sperm Capacitation; Sperm Motility; Spermatozoa; Testis; Tyrosine; Vanadium Compounds; cyclic AMP dependent protein kinase; tyrosine; vanadium; cyclic AMP dependent protein kinase; tyrosine; vanadium derivative; vanadium pentoxide; animal experiment; animal model; animal tissue; Article; cell density; controlled study; enzyme activity; germ cell; male; male fertility; mouse; nonhuman; protein phosphorylation; reproductive toxicity; semen analysis; spermatozoon capacitation; spermatozoon motility; Western blotting; animal; Bagg albino mouse; drug effect; metabolism; pathology; phosphorylation; physiology; sperm capacitation; spermatozoon; spermatozoon motility; testis | English | 2020 | 2020-09 | 10.1016/j.reprotox.2020.07.002 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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