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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Pure varus posteromedial rotatory instability of the elbow: Radiographic findings, treatment, and outcomes | Introduction: Although varus posteromedial rotatory instability (VPMRI) is a subtle elbow injury that involves anteromedial coronoid facet (AMCF) fracture and ligamentous injuries, treatment options and outcomes of VPMRI remains controversial. The aim of this study was to investigate radiographic findings, treatments, and outcomes of a large series of VPMRI. Methods: We retrospectively reviewed 91 pure VPMRI cases with AMCF fracture (O 'Driscoll classification anteromedial type) which were treated at 6 hospitals. Clinical and radiographic outcomes were investigated with a mean follow-up period of 46.8 months using the Mayo elbow performance score (MEPS), and the Quick Disabilities of the Arm, Shoulder and Hand (Quick -DASH) score, and serial plain radiographs. Results: In AMCF fracture, there were 4 cases of subtype 1, 67 cases of subtype 2, and 20 cases of subtype 3. On MRI, complete tears of lateral collateral ligament and medial collateral ligament were observed in 83.1 % (59/71 cases) and 33.8 % (24/71 cases). Operative treatment was performed in 68 cases (74.7 %) including both side fixation in 40 cases (58.8 %), medial side fixation only in 17 cases (25.0 %), and lateral side fixation only in 11 cases (16.2 %). Nonoperative treatment was performed in 23 cases (25.3 %). The mean final MEPS and QuickDASH scores were 93.7 and 7.9. The overall complication and reoperation rates were 22.0 % and 15.4 %. No significant differences regarding final clinical scores and range of motions were observed between the operative group and the nonoperative group, but significant differences were observed regarding number (p = 0.019) and displacement (p = 0.002) of coronoid fragment, and complication rate (p < 0.001) between the two groups. Conclusion: Depending on the pattern of coronoid fragment and the degree of ligamentous injuries, operative treatment of unstable VPMRI using various fixation techniques including coronoid fixation and ligament repair yielded satisfactory final clinical outcomes. However, surgeons should be aware of the high complication and reoperation rates after operative treatment. Stable VPMRI with AMCF fracture involving minimal displacement or small number of fragments can be treated nonoperatively. | Cho, Chul-Hyun; Kim, Ji-Hoon; Kim, Beom-Soo; Rhyou, In Hyeok; Shin, Dongju; Kim, Youngbok; Kim, Jung-Han; Yoon, Jong Pil; Kim, Du-Han | Keimyung Univ, Dongsan Hosp, Dept Orthoped Surg, Sch Med, 1035 Dalgubul Ro, Daegu 42601, South Korea; Pohang Semyeng Christianity Hosp, Upper Extrem & Microsurg Ctr, Dept Orthopaed Surg, Pohang, South Korea; W Hosp, Dept Orthoped Surg, Daegu, South Korea; Inje Univ, Haeundae Paik Hosp, Coll Med, Dept Orthoped Surg, Busan, South Korea; Inje Univ, Busan Paik Hosp, Coll Med, Dept Orthoped Surg, Busan, South Korea; Kyungpook Natl Univ, Coll Med, Dept Orthopaed Surg, Deagu, South Korea | ; , Do Hyun Kim/J-4567-2017 | 35785599900; 57991295600; 57161242900; 36613502700; 57222389557; 57194722582; 57203324813; 36098548400; 57192702203 | osmdkdh@gmail.com; | INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | INJURY | 0020-1383 | 1879-0267 | 55 | 8 | SCIE | CRITICAL CARE MEDICINE;EMERGENCY MEDICINE;ORTHOPEDICS;SURGERY | 2024 | 2 | 33.0 | 0 | 2025-05-07 | 0 | 0 | Elbow; Dislocation; Varus instability; Posteromedial instability; Coronoid; Fracture | ANTEROMEDIAL CORONOID FRACTURES; COLLATERAL LIGAMENT; FACET FRACTURES; RADIAL HEAD; CLASSIFICATION; FIXATION; INJURY; LOOP | Coronoid; Dislocation; Elbow; Fracture; Posteromedial instability; Varus instability | Adult; Aged; Collateral Ligaments; Elbow Injuries; Elbow Joint; Female; Fracture Fixation, Internal; Humans; Joint Instability; Magnetic Resonance Imaging; Male; Middle Aged; Radiography; Range of Motion, Articular; Retrospective Studies; Treatment Outcome; Ulna Fractures; Young Adult; adolescent; adult; aged; anteromedial coronoid facet fracture; Article; clinical outcome; closed fracture reduction; cohort analysis; comorbidity; conservative treatment; cubitus varus; Disabilities of the Arm, Shoulder and Hand (score); elbow dislocation; elbow fracture; elbow injury; elbow radiography; elbow stiffness; female; follow up; heterotopic ossification; human; interrater reliability; intrarater reliability; joint instability; lateral collateral ligament; ligament injury; major clinical study; male; Mayo Elbow Performance Score; medial collateral ligament; osteotomy; postoperative complication; reoperation; retrospective study; sport injury; traffic accident; ulnar nerve compression; varus posteromedial rotatory instability; visual analog scale; x-ray computed tomography; collateral ligament; diagnostic imaging; elbow injury; elbow joint; injury; joint instability; middle aged; nuclear magnetic resonance imaging; osteosynthesis; pathophysiology; procedures; radiography; range of motion; surgery; therapy; treatment outcome; ulna fracture; young adult | English | 2024 | 2024-08 | 10.1016/j.injury.2024.111628 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Unpowered scooter injuries in children and risk factors for traumatic brain injuries: An 8-year cross-sectional study using a national registry in South Korea | Introduction: Head trauma accounts for a large proportion of unpowered scooter injuries in children. Traumatic brain injury (TBI) is the leading cause of considerable mortality and morbidity in children, who are the main users of unpowered scooters. The aim of this study was to explore the characteristics of unpowered scooter injuries in children and to identify predictors of the occurrence of TBI. Methods: A multicentre observational retrospective study was conducted using the Emergency Department-based Injury In-depth Surveillance (EDIIS) database in South Korea. Children aged 2 to 18 years old with unpowered scooter injuries between 2011 and 2018 were eligible for inclusion in this study, and the primary outcome was TBI defined based on the International Classification of Diseases, 10th Revision (ICD-10) code. Results: The annual rate of unpowered scooter injuries per 1,000 injured patients increased throughout the study period from 1.4 in 2011 to 16.4 in 2018 (P for trend < 0.001). Of the 3,892 children who had unpowered scooter injuries, 353 (9.2 %) had TBI. Children were at a higher risk of unpowered scooter TBI if they were aged between 2 and 5 years (adjusted odds ratio [aOR]: 1.37; 95 % confidence interval (CI): 1.09-1.73), were male (aOR: 1.45; 95 % CI: 1.14-1.86), were injured either on sidewalks (aOR: 1.80; 95 % CI: 1.20-2.70) or on driveways (aOR: 2.31; 95 % CI: 1.41-3.79), and experienced a fall (aOR: 1.98; 95 % CI: 1.15-3.43). Additionally, children injured after a blunt force were at a lower risk of TBI (aOR: 0.28; 95 % CI: 0.15-0.53). Conclusion: Unpowered scooter injuries in children are increasing in South Korea. It is essential for younger children riding unpowered scooters to wear helmets and for caregivers to actively supervise their children to prevent TBI. | Ni Lee, Ha; Park, Joong Wan; Jung, Jae Yun; Kim, Do Kyun; Kwak, Young Ho; Hwang, Soyun; Lee, Eui Jun; Kim, Jin Hee; Jue, Jie Hee | Seoul Natl Univ Hosp, Dept Emergency Med, 101 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Disaster Med Res Ctr, Med Res Ctr, 103 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Coll Med, Dept Emergency Med, 103 Daehak ro, Seoul 03080, South Korea; Severance Childrens Hosp, Dept Pediat, 50-1 Yonsei Ro, Seoul 03722, South Korea; Kyungpook Natl Univ, Dept Pediat, Chilgok Hosp, 807 Hoguk Ro, Daegu 41404, South Korea | Kim, Jin/AET-7817-2022; , DO KYUN KIM/Q-3070-2018; Kwak, Young/J-5373-2012 | 57215346592; 57203536959; 54968964600; 8726745300; 56588521700; 55759248500; 57212665865; 58757814600; 58026630200 | zzibii@naver.com; | INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | INJURY | 0020-1383 | 1879-0267 | 55 | 1 | SCIE | CRITICAL CARE MEDICINE;EMERGENCY MEDICINE;ORTHOPEDICS;SURGERY | 2024 | 2 | 33.0 | 1.07 | 2025-04-16 | 1 | 2 | Child; Wounds and injuries; Traumatic brain injury; Republic of Korea | EPIDEMIOLOGY; VALIDATION | Child; Republic of Korea; Traumatic brain injury; Wounds and injuries | Adolescent; Brain Injuries, Traumatic; Child; Child, Preschool; Cross-Sectional Studies; Female; Head Protective Devices; Humans; Male; Registries; Republic of Korea; Retrospective Studies; Risk Factors; adult; Article; blunt trauma; child; controlled study; cross-sectional study; crush trauma; emergency ward; female; general practitioner; head injury; hospitalization; human; ICD-10; informed consent; major clinical study; male; morbidity; mortality; national health organization; residential area; retrospective study; risk factor; scooter; South Korea; traumatic brain injury; World Health Organization; adolescent; preschool child; register; risk factor; South Korea; traumatic brain injury | English | 2024 | 2024-01 | 10.1016/j.injury.2023.111197 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Analgesic Efficacy of Epidural Patient-Controlled Analgesia on Cancer Pain: A Retrospective Observational Study | Background: In patients with severe cancer pain, systemic analgesics are often refractory or have limited application due to the side effects of opioids. In these cases, epidural analgesia may be effective. However, data on the effects of epidural patient -controlled analgesia (PCA) on cancer pain are limited. Objectives: To evaluate the analgesic efficacy of epidural PCA in patients with cancer pain through a retrospective chart review. Study Design: Retrospective analysis. Setting: A single academic center in Daegu, South Korea. Methods: The analgesic efficacy of epidural PCA on cancer pain was analyzed in patients who underwent epidural PCA using a disposable balloon pump with a flow regulator between 2012 and 2021. The pump was filled with a 600-mL mixture of 6 ampoules of 0.2% ropivacaine, 1 mg fentanyl, and normal saline. For the first use of epidural PCA, the basal rate, bolus dose, and lockout time were set as 4 mL/h, 2 mL, and 15 min, respectively. The basal rate was increased and decreased depending on the degree of pain relief effect and occurrence of side effects, respectively. To increase the usage time of epidural PCA and reduce the patient's cost burden, the fentanyl dose was increased by 1 mg when the disposable balloon pump was replaced with a new one after exhaustion of the drug if no side effects from the previous dose were observed. Analgesic efficacy was confirmed by comparing the number of types and the total amount of opioids used in patients before and after epidural PCA application in terms of the equivalent dose of oral morphine. Results: Epidural catheterization was performed 105 times, and PCA was refilled 257 times in 88 patients. On average, epidural catheterization was performed 1.2 +/- 0.4 (1-3) times, and epidural PCA was refilled 3.2 +/- 2.3 (1-11) times per patient. The mean duration of PCA use was 15.6 +/- 13.4 (1-82) days. The mean number of opioid types used the day before the procedure and the mean smallest number of opioids used per day up to 5 days after the procedure were 3.4 +/- 1.2 and 2.4 +/- 1.4, respectively (P < 0.05). The total amount of opioids used the day before the procedure and the smallest total amount of opioids used per day up to 5 days after the procedure were converted into oral morphine equivalent doses, respectively, and the mean doses were 449.5 +/- 555.9 and 331.9 +/- 462.8 mg, respectively (P < 0.05). Limitations: The study results are the author's observations from a single center. Epidural PCA was performed only on hospitalized patients. Individual differences were not considered in the composition of drugs for PCA. Transmucosal immediate -release fentanyl was not accurately converted to oral morphine; thus, it was excluded from the analysis of the total amount used, and the effect of adjuvant analgesics could not be considered. Conclusion: Epidural PCA using subcutaneous tunneling is a useful cancer pain control method. Furthermore, it can be safely used for a longer duration owing to its low infection risk. | Park, Jun-Mo | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Anesthesiol & Pain Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Anesthesiol & Pain Med, Chilgok Hosp, 807 Hoguk Ro,Bukgu, Daegu 41404, South Korea | 55967725100 | pjm4013@knu.ac.kr; | PAIN PHYSICIAN | PAIN PHYSICIAN | 1533-3159 | 27 | 1 | SCIE | ANESTHESIOLOGY;CLINICAL NEUROLOGY | 2024 | 2.5 | 33.1 | 0.76 | 2025-04-16 | 1 | 1 | Cancer pain; epidural; epidural analgesia; fentanyl; pain; patient-controlled analgesia; ropivacaine; tunneling | CATHETER; GUIDELINES; COMPLICATIONS; INFECTIONS; FIXATION; RELIEF; CRISIS | Cancer pain; epidural; epidural analgesia; fentanyl; pain; patient-controlled analgesia; ropivacaine; tunneling | Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cancer Pain; Fentanyl; Humans; Morphine Derivatives; Neoplasms; Pain; Retrospective Studies; analgesic agent; fentanyl; morphine derivative; narcotic analgesic agent; cancer pain; complication; human; neoplasm; pain; patient controlled analgesia; retrospective study | English | 2024 | 2024 (JAN-FEB) | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis | Background Avascular necrosis (AVN) is a medical condition characterized by the destruction of bone tissue due to a diminished blood supply. When the rate of tissue destruction surpasses the rate of regeneration, effective treatment becomes challenging, leading to escalating pain, arthritis, and bone fragility as the disease advances. A timely diagnosis is imperative to prevent and initiate proactive treatment for osteonecrosis. We explored the potential of differentially expressed proteins in serum-derived extracellular vesicles (EVs) as biomarkers for AVN of the femoral head in humans. We analyzed the genetic material contained in serum-derived exosomes from patients for early diagnosis, treatment, and prognosis of avascular necrosis.Methods EVs were isolated from the serum of both patients with AVN and a control group of healthy individuals. Proteomic analyses were conducted to compare the expression patterns of these proteins by proteomic analysis using LC-MS/MS.Results Our results show that the levels of IGHV3-23, FN1, VWF, FGB, PRG4, FCGBP, and ZSWIM9 were upregulated in the EVs of patients with AVN compared with those of healthy controls. ELISA results showed that VWF and PRG4 were significantly upregulated in the patients with AVN.Conclusions These findings suggest that these EV proteins could serve as promising biomarkers for the early detection and diagnosis of AVN. Early diagnosis is paramount for effective treatment, and the identification of new osteonecrosis biomarkers is essential to facilitate swift diagnosis and proactive intervention. Our study provides novel insights into the identification of AVN-related biomarkers that can enhance clinical management and treatment outcomes. | Sung, Soo-Eun; Lim, Ju-Hyeon; Kang, Kyung-Ku; Choi, Joo-Hee; Lee, Sijoon; Sung, Minkyoung; Park, Wook-Tae; Kim, Young-In; Seo, Min-Soo; Lee, Gun Woo | Daegu Gyeongbuk Med Innovat Fdn K MedI Hub, Preclin Res Ctr, Daegu 41061, South Korea; Korea Biome Res Lab, Kolmar Korea Holdings, 61Heolleungro 8 Gil, Seoul 06800, South Korea; Yeungnam Univ, Med Ctr, Coll Med, Dept Orthoped Surg, 170 Hyonchung Ro, Namgu 42415, Daegu, South Korea; Cellexobio Ltd, Daegu 42415, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Vet Tissue Engn, Daegu 41566, South Korea | Lee, Sijoon/LIC-1291-2024 | 56051194000; 57218821150; 57215079376; 55882556800; 57219164019; 57256838000; 57216658028; 57203948912; 35254332100; 55599978600 | msseo@knu.ac.kr;gwlee1871@ynu.ac.kr; | CLINICAL PROTEOMICS | CLIN PROTEOM | 1542-6416 | 1559-0275 | 21 | 1 | SCIE | BIOCHEMICAL RESEARCH METHODS | 2024 | 3.3 | 33.1 | 1.06 | 2025-05-07 | 2 | 2 | Avascular necrosis; Osteonecrosis; Extracellular vesicles; Diagnosis | FEMORAL-HEAD; PROTEOGLYCAN 4; OSTEONECROSIS; FIBRONECTIN; EXPRESSION; PROGNOSIS; PREDICTS; DISEASE | Avascular necrosis; Diagnosis; Extracellular vesicles; Osteonecrosis | binding protein; biological marker; Fc gamma binding protein; fibrinogen; fibrinogen beta chain; immunoglobulin heavy chain; immunoglobulin heavy variable 3-23; immunoglobulin lambda chain; immunoglobulin lambda chain 3-1; peroxiredoxin 1; proteoglycan; proteoglycan 4; spastic ataxia of Charlevoix protein; SWIM type containing 9; unclassified drug; adult; Article; avascular necrosis; blood analysis; bone necrosis; clinical article; controlled study; early diagnosis; early intervention; enzyme linked immunosorbent assay; exosome; gene expression regulation; human; human cell; male; micellar liquid chromatography; middle aged; patient care; prognosis; protein function; proteomics; serum derived extracellular vesicle; upregulation | English | 2024 | 2024-12 | 10.1186/s12014-024-09489-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Radiocarbon research on meltwater and carbon cycling in the polar oceans in a changing climate | Radiocarbon (14C) 14 C) is a widely used tool with applications that transcend disciplinary boundaries, including the marine chemistry field. The development of 14 C measurement techniques and icebreaking research vessels especially encourage and support polar research using 14 C. Research examining 14 C in polar oceans in the context of climate change has led to considerable insight into the marine carbon cycle. A comprehensive review of the principles, applications, progress, and challenges of 14 C will undoubtedly advance related polar research. This review compiled available literature on 14 C in the polar oceans and summarizes current progresses in carbon cycling, glacial and ice sheet dynamics, water circulation, and ventilation. The impact of warming induced melting sea ice and glaciers on marine biogeochemical cycles, future environmental challenges and research directions have also been summarized. The limitations of existing 14 C research in polar regions can be addressed through well-designed and continuous investigation, data and sample sharing, and the development of state-ofthe-art 14 C measurement techniques. | Fang, Ling; Kim, Hojung; Shangguan, Donghui; Kim, Minkyoung | Northwest Univ, Urban & Environm Sci Dept, Shaanxi Key Lab Earth Surface Syst & Environm Carr, Xian, Peoples R China; Chinese Acad Sci, Inst Tibetan Plateau Res, State Key Lab Tibetan Plateau Earth Syst Environm, Beijing, Peoples R China; Kyungpook Natl Univ, Coll Nat Sci, Sch Earth Syst Sci, Dept Oceanog, Daegu, South Korea; Chinese Acad Sci, Northwest Inst Ecoenvironm & Resources, Lanzhou, Peoples R China; Kyungpook Natl Univ, KNU Inst Basic Sci, KNU G LAMP Project Grp, Daegu, South Korea | 58183605000; 59204976800; 7005703628; 57212315624 | minkyoung@knu.ac.kr; | MARINE CHEMISTRY | MAR CHEM | 0304-4203 | 1872-7581 | 265 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;OCEANOGRAPHY | 2024 | 2.5 | 33.1 | 0.15 | 2025-05-07 | 1 | 1 | Radiocarbon; Carbon cycling; Polar oceans; Climate change | PARTICULATE ORGANIC-CARBON; ANTARCTIC ICE-SHEET; SINKING PARTICLE-FLUX; WESTERN ARCTIC-OCEAN; DEEP SOUTHERN-OCEAN; AMUNDSEN SEA; WATER COLUMN; BEAUFORT SEA; ROSS SEA; C-14 | Carbon cycling; Climate change; Polar oceans; Radiocarbon | Carbon capture and utilization; Carbon sequestration; Radiation chemistry; Carbon cycling; Changing climate; Disciplinary boundaries; Marine carbon cycle; Marine chemistry; Measurement techniques; Polar Oceans; Polar research; Radiocarbon; Research vessels; carbon cycle; climate change; ice sheet; meltwater; radiocarbon dating; sea ice; Sea ice | English | 2024 | 2024-09 | 10.1016/j.marchem.2024.104442 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Application of psychrotolerant quorum quenching Planococcus versutus sp. L10.15T to membrane bioreactors for biofouling control at low temperatures | Bacterial quorum quenching (QQ) (e.g., degradation of N-acyl homoserine lactones (AHLs)) has been utilized to mitigate biofouling in membrane bioreactors (MBRs). However, the anti-biofouling efficiency of QQ bacteria may decrease at low temperatures. To enhance the resilience of QQ technology to cold climates, psychrotolerant Planococcus versutus sp. L10.15(T) was applied to MBRs at 10 degrees C in the form of polymeric beads entrapping L10.15(T). The efficiency of AHL degradation by L10.15(T)-beads was compared to that by beads entrapping Rhodococcus sp. BH4, a QQ bacterium that has been widely used in MBRs at room temperature. The AHL degradation by the L10.15(T)-beads was more efficient than that by the BH4-beads for most types of AHLs tested at 10 degrees C. The application of the L10.15(T)-beads to a continuous MBR at 10 degrees C exhibited that the anti-biofouling efficiency of L10.15(T) was greater than that of BH4 through more effective reduction in extracellular polymeric substances in the biocake on the membrane surface. | Min, Sojin; Lee, Hosung; Lim, Joowan; Lee, Sang Hyun; Lee, Seungjin; Choo, Kwang-Ho; Lee, Chung-Hak; Park, Pyung-Kyu | Yonsei Univ, Dept Environm & Energy Engn, Wonju 26493, Gangwon Do, South Korea; Univ Minnesota, Dept Earth & Environm Sci, Minneapolis, MN 55455 USA; Georgia Gwinnett Coll, Dept Chem, Lawrenceville, GA 30043 USA; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Seoul Natl Univ, Sch Chem & Biol Engn, Seoul 08826, South Korea | Choo, Kwang-Ho/A-3456-2016 | 57193696052; 57203159640; 57203499104; 59851188800; 53875230700; 7102083272; 7410142508; 7202425104 | pkpark@yonsei.ac.kr; | ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY | ENVIRON SCI-WAT RES | 2053-1400 | 2053-1419 | 10 | 3 | SCIE | ENVIRONMENTAL SCIENCES;WATER RESOURCES;ENGINEERING, ENVIRONMENTAL | 2024 | 3.1 | 33.2 | 0.37 | 2025-05-07 | 1 | 1 | PARADIGM; MBR | Bacteria; Biofouling; Efficiency; Quenching; Antibiofouling; Biofouling control; Colder climate; Lows-temperatures; N-Acyl Homoserine lactones; Polymeric beads; Psychrotolerant; Quenching technology; Quorum quenching; Rhodococcus sp; bacterium; biofouling; bioreactor; efficiency measurement; low temperature; membrane; polymer; water technology; Bioreactors | English | 2024 | 2024-03-01 | 10.1039/d3ew00705g | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Biological activities, identification, method development, and validation for analysis of polyphenolic compounds in Nymphaea rubra flowers and leaves by UHPLC-Q-cIM-TOF-MS and UHPLC-TQ-MS | Introduction: Nymphaea rubra belongs to the Nymphaea family and is regarded as a vegetable used in traditional medicine to cure several ailments. These species are rich in phenolic acid, flavonoids, and hydrolysable tannin. Objective: This study aimed to assess the biological activities of Nymphaea rubra flowers (NRF) and leaves (NRL) by identifying and quantifying their polyphenolic compounds using ultra-performance liquid chromatography coupled to quadrupole cyclic ion mobility time-of-flight mass spectrometry (UHPLC-Q-cIM-TOF-MS) and triple quadrupole mass spectrometry (UHPLC-TQ-MS). Methodology: NRF and NRL powder was extracted with methanol and fractionated using hexane, ethylacetate, and water. Antioxidant and alpha-glucosidase, and tyrosinase enzyme inhibitory activities were evaluated. The polyphenolic components of NRF and NRL were identified and quantified using UHPLC-Q-cIM-TOF-MS and UHPLC-TQ-MS. The method was validated using linearity, precision, accuracy, limit of detection (LOD), and lower limit of quantification (LLOQ). Results: Bioactive substances and antioxidants were highest in the ethylacetate fraction of flowers and leaves. Principal component analysis showed how solvent and plant components affect N. rubra's bioactivity and bioactive compound extraction. A total of 67 compounds were identified, and among them 21 significant polyphenols were quantified. Each calibration curve had R-2 > 0.998. The LOD and LLOQ varied from 0.007 to 0.09 mu g/mL and from 0.01 to 0.1 mu g/mL, respectively. NRF contained a significant amount of gallic acid (10.1 mg/g), while NRL contained abundant pentagalloylglucose (2.8 mg/g). Conclusion: The developed method is simple, rapid, and selective for the identification and quantification of bioactive molecules. These findings provide a scientific basis for N. rubra's well-documented biological effects. | Naznin, Marufa; Alam, Rafiqul; Alam, Md Badrul; Jung, Maeng-Joon; Lee, Sang-Han; Kim, Sunghwan | Kyungpook Natl Univ, Dept Chem, Daegu, South Korea; Kyungpook Natl Univ, Grad Sch, Dept Food Sci & Biotechnol, Daegu, South Korea; Kyungpook Natl Univ, Food & Bioind Res Inst, Inner Beauty Antiaging Ctr, Daegu, South Korea; Mass Spectrometry Converging Res Ctr, Daegu, South Korea; Green Nano Mat Res Ctr, Daegu, South Korea; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Grad Sch, Dept Food Sci & Biotechnol, Daegu 41566, South Korea | ; Kim, Sunghwan/HKN-9812-2023; Lee, Seung Eun/ABG-1607-2021; Alam, Md Badrul/AFL-7668-2022 | 57195955389; 57219723992; 56706777100; 56291394700; 57221453703; 57203772967 | sang@knu.ac.kr;sunghwank@knu.ac.kr; | PHYTOCHEMICAL ANALYSIS | PHYTOCHEM ANALYSIS | 0958-0344 | 1099-1565 | 35 | 4 | SCIE | BIOCHEMICAL RESEARCH METHODS;CHEMISTRY, ANALYTICAL;PLANT SCIENCES | 2024 | 2.6 | 33.2 | 0 | 2025-05-07 | 1 | 1 | biological activities; nymphaea rubra; polyphenols; UHPLC-Q-cIM-TOF-MS | HYDROLYZABLE TANNINS; PHENOLIC-ACIDS; ANTIOXIDANT; EXTRACTS; GLYCOSIDES | biological activities; nymphaea rubra; polyphenols; UHPLC-Q-cIM-TOF-MS | alpha-Glucosidases; Antioxidants; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flowers; Mass Spectrometry; Monophenol Monooxygenase; Nymphaea; Plant Extracts; Plant Leaves; Polyphenols; Reproducibility of Results; Antioxidants; Drug products; Inductively coupled plasma; Liquid chromatography; Mass spectrometry; Medicine; Plants (botany); Polyphenolic compounds; Principal component analysis; 2 deoxy 2,3 dehydro n acetylneuraminic acid; 6,8 di c glucopyranosyl naringenin; acetic acid ethyl ester; alpha glucosidase; alpha glucosidase inhibitor; angoroside A; antioxidant; astragalin; brevifolin; brevifolin carboxylic acid; caffeic acid; calomacrin B; carboxylic acid; catechin; chlorogenic acid; corilagin; coumaric acid; digallic acid; digalloylglucose; ellagic acid; epigallocatechin gallate; ethylgallate; ferulic acid; flavonoid; formic acid; gallic acid; ganoderenic acid A; ganolucidic acid A; glucose pentagallate; hesperetin; hexane; hirsutanonol 5 o glucoside; hispidulin; hydrangenoside c; hydroxyadipic acid; iriflophenone 3 glucoside; irisxanthone; isorhamnetin; kaempferol; lactupicrin methyl ester; licarin A; linoleic acid; lipid; luteolin; mangiferin; methanol; methyl dodecanoic acid; methylbrevifolin carboxylate; methylgallate; monophenol monooxygenase; myricetin arabinoside; myricitrin; naringenin; nicotiflorin; nymphaeoside A; oleic acid; oxygenase inhibitor; polyphenol; polyphenol derivative; proanthocyanidin; protocatechuic acid; prunin; pyroglutamic acid; quercetin; quercetin xyloside; quinic acid; rosmarinic acid; saponaretin; shikimic acid; sialic acid; stearic acid; syringic acid; tannin; tannin derivative; taxifolin; terpenoid; tricoumaroyl spermidine; unclassified drug; vanillic acid; vicenin 2; water; xanthone derivative; antioxidant; enzyme inhibitor; plant extract; polyphenol; Detection limits; Ethyl-acetate; Identification method; Limit of detection; Lower limit of quantifications; Nymphaea; Nymphaea rubra; Polyphenols; Triple-quadrupole mass spectrometry; UHPLC-Q-cIM-TOF-MS; antioxidant activity; Article; chemometric analysis; controlled study; enzyme inhibition; flower; limit of detection; limit of quantitation; nonhuman; Nymphaea; Nymphaea rubra; plant leaf; time of flight mass spectrometry; triple quadrupole mass spectrometry; ultra performance liquid chromatography; chemistry; high performance liquid chromatography; mass spectrometry; metabolism; procedures; reproducibility; Bioactivity | English | 2024 | 2024-06 | 10.1002/pca.3329 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Meeting Abstract | The characteristics and treatment patterns in haemophilia B patients receiving recombinant coagulation factor IX | Park, Young Shil; Hwang, Tai Ju; Park, Sang Kyu; Choi, Eun Jin; Park, Jeong A.; Baek, Hee Jo; Lyu, Chuhl Joo; Lee, Jae Hee; Kim, Mi Kyung; Kim, Ji Yoon; Lee, Sun Ah; Park, Boram; Kim, Da-Hye; Chung, Sung Beom; Nam, Chung-Mo; Lee, Yaeji; Yoo, Ki Young | Kyung Hee Univ Hosp Gangdong, Dept Pediat, Seoul, South Korea; Korea Hemophilia Fdn Clin, Gwangju, South Korea; Korea Hemophilia Fdn Clin, Busan, South Korea; Daegu Catholic Univ, Dept Pediat, Med Ctr, Daegu, South Korea; Inha Univ Hosp, Dept Pediat, Incheon, South Korea; Chonnam Natl Univ, Med Sch, Hwasun Hosp, Dept Pediat, Gwangju, South Korea; Yonsei Univ, Dept Pediat Hematol Oncol, Coll Med, Seoul, South Korea; Chungbuk Natl Univ, Dept Pediat, Sch Med, Chungbuk Natl Univ Hosp, Cheongju, South Korea; Presbyterian Med Ctr, Dept Pediat, Jeonju, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Pediat, Daegu, South Korea; Daegu Fatima Hosp, Dept Internal Med, Daegu, South Korea; Pfizer Pharmaceut Korea Ltd, Med Dept, Seoul, South Korea; Yonsei Univ, Dept Prevent Med, Coll Med, Seoul, South Korea; Yonsei Univ, Dept Biostat & Comp, Seoul, South Korea; Korea Hemophilia Fdn Clin, Seoul, South Korea | Park, Jung Hoon/CZZ-0090-2022 | HAEMOPHILIA | HAEMOPHILIA | 1351-8216 | 1365-2516 | 30 | SCIE | HEMATOLOGY | 2024 | 3 | 33.2 | 0 | Regular prophylaxis treatment is recommended over episodic treatment; Real-World Data; High-dose factor IX regimen provides significantly better effect than low-dose regimen in preventing bleeding in the following month | English | 2024 | 2024-04 | 바로가기 | 바로가기 | |||||||||||||||
| ○ | Article | An analytic hierarchy process for the sustainable development of small- and medium-sized enterprises in the manufacturing sector, South Korea | The global climate action requires the manufacturing sector to decrease greenhouse gas (GHG) emissions by establishing carbon pricing mechanisms. Particularly, small- and medium-sized enterprises (SMEs) do not have the resources needed to reduce emissions. The purpose of the study is to investigate which GHG reduction technologies would be appropriate for SMEs to efficiently reduce emissions by lessening the economic loss during the transition to green manufacturing. An analytic hierarchy process (AHP) method is employed to prioritize the GHG reduction technologies for SMEs in the manufacturing sector. Groups with a consistency ratio (CR) below 0.1 and a group with a CR below 0.2 are divided for comparison. The results show that, in both the CR < 0.1 and CR < 0.2 groups, “Innovative industrial process” is the most essential criterion among the three criteria. Regarding the sub-criterion, “Electrification of manufacturing facilities” is the most important, followed by “Management after process”. CR < 0.1 and CR < 0.2 groups do not show a large difference in prioritization. Based on the results, it is suggested that an eco-industrial park be established to achieve progress in a collective manner. The case study of Busan metropolitan city has implications for policy-making at the national level for GHG reduction among SMEs. © The Author(s), under exclusive licence to Springer Nature B.V. 2024. | Nam, Hoseok; Cho, Youngheon; Kim, Junyoung; Joo, Yejin; Nam, Hyungseok | Busan Development Institute, 955 Jungangdae-ro, Busan, 47210, South Korea; Busan Development Institute, 955 Jungangdae-ro, Busan, 47210, South Korea; Participation and Communication Division, Ministry of Unification, 209 Sejong-daero, Seoul, 03171, South Korea; Department of Economics, Seoul National University, 1 Gwanak-ro, Seoul, 08826, South Korea; School of Mechanical Engineering, Kyungpook National University, 80 Daehak-ro, Daegu, 41566, South Korea | 57198350465; 59478207000; 59478207100; 59147367800; 57190418228 | namhs219@knu.ac.kr; | Environment, Development and Sustainability | ENVIRON DEV SUSTAIN | 1387-585X | 1573-2975 | SCIE | ENVIRONMENTAL SCIENCES;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2024 | 4.2 | 33.3 | 0.43 | 2025-05-07 | 1 | Busan metropolitan city; Green manufacturing; Greenhouse gas reduction; Manufacturing sector; SMEs | English | Article in press | 2024 | 10.1007/s10668-024-05860-3 | 바로가기 | 바로가기 | 바로가기 | ||||||||||
| ○ | ○ | Article | Clinical Values of Whole-Body Blood Pool Scans and SPECT for Evaluation of Congenital Vascular Malformation | Purpose This study examines the diagnostic potential of whole-body blood pool scintigraphy (WBBPS) using technetium-99 m-labeled red blood cells to detect congenital vascular malformations (CVMs). It aims to compare its efficacy with traditional imaging techniques such as magnetic resonance imaging (MRI) and ultrasonography (USG), emphasizing its potential advantages in terms of characterization of lesions and capacity for whole-body assessment.Methods The efficacy of WBBPS and single-photon emission computed tomography (SPECT)/computed tomography (CT) imaging in diagnosing CVMs, comparing them with USG and MRI results, was evaluated in this retrospective study. Of the 38 patients, 21 were evaluated using these diagnostic methods, with CVMs classified according to the International Society for the Study of Vascular Anomalies guidelines. Also, this study aimed to elucidate the characteristics between WBBPS, SPECT/CT, USG, or MRI findings and their consistency with the final diagnosis.Results A total of 21 participants were included in this study, with an average age of 17.7 years old, with female predominance (57.1%). The most common diagnosis was vascular malformations (VMs) (71.4%), followed by combined vascular malformations (14.3%) and lymphatic malformations (9.5%). WBBPS demonstrated positive results in 95.2% of cases. Distinct imaging patterns for each condition were observed, with WBBPS being crucial in locating lesions.Conclusion The study findings suggested that WBBPS with SPECT/CT could be helpful in detecting occult VM lesions and ruling out a lymphatic malformation diagnosis. Thus, it can be employed in the evaluation of CVMs. | Son, Junik; Hong, Chae Moon; Lee, Jaetae; Chung, Ho Yun; Ahn, Byeong-Cheol | Kyungpook Natl Univ Hosp, Dept Nucl Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Nucl Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Vasc Anomalies Ctr, Dept Plast, Daegu, South Korea; Kyungpook Natl Univ Hosp, Vasc Anomalies Ctr, Dept Reconstruct Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Plast, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Reconstruct Surg, Daegu, South Korea | Son, Junik/GVU-0832-2022 | 57408265500; 37050876700; 7601451907; 7404007181; 7202791511 | dimiaru_jun@outlook.kr;shahking@hanmail.net;jaetae@knu.ac.kr;hy-chung@knu.ac.kr;abc2000@knu.ac.kr; | NUCLEAR MEDICINE AND MOLECULAR IMAGING | NUCL MED MOLEC IMAG | 1869-3474 | 1869-3482 | 58 | 2 | ESCI | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2024 | 2.7 | 33.3 | 0 | 2025-05-07 | 0 | 0 | Congenital vascular malformation; Tc-99m-labeled red blood cells; Whole-body blood pool scintigraphy; SPECT/CT; Venous malformation; Lymphatic malformation | ETHANOL SCLEROTHERAPY; VENOUS MALFORMATIONS; SCINTIGRAPHY; DIAGNOSIS; PERFUSION; HEAD; CLASSIFICATION; HEMANGIOMAS; MANAGEMENT | <sup>99m</sup>Tc-labeled red blood cells; Congenital vascular malformation; Lymphatic malformation; SPECT/CT; Venous malformation; Whole-body blood pool scintigraphy | technetium 99m; adolescent; angioosteohypertrophy syndrome; Article; blood flow; child; clinical article; computer assisted tomography; congenital blood vessel malformation; echography; erythrocyte; evaluation study; female; human; imaging; lymphatic malformation; male; nuclear magnetic resonance imaging; preschool child; retrospective study; single photon emission computed tomography; T1 weighted imaging; T2 weighted imaging; whole body blood pool scan; whole body scintiscanning | English | 2024 | 2024-04 | 10.1007/s13139-023-00835-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Enhancing resilience in agricultural production systems with AI-based technologies | Agricultural production systems play a crucial role in global societal sustenance as they provide the world's food, fuel, and fiber supplies. However, these systems face numerous challenges including climate change and resource depletion. Modern technologies powered by artificial intelligence (AI) can help address these challenges by contributing to revolutionizing agricultural production and building resilience. While there has been a growing body of research on AI-based technologies in agricultural production systems, comprehensive literature reviews on the potential of AI-based technologies in enhancing resilience, and sustainability in agricultural production systems is lacking to the extent of the authors' knowledge. Additionally, some studies have focused on specific AI-based technologies such as internet of things, creating a gap in ascertaining the impact of the cumulative application of these techniques. This review aims to fill these gaps by exploring the trends in the emergence of AI technologies and applications in agricultural production systems. It also investigates the integration of these technologies into traditional farming operations and driving climate-smart agriculture (CSA). Data on automation systems, AI applications, and CSA were gathered from peer-reviewed publications, reports, and public databases. Two Natural Language Processing (NLP) tools were utilized: the Iris.ai application and an in-house NLP tool developed with Fast.ai-NLP (the Fast.ai deep learning library). The Iris.ai-NLP tool extracted a thousand papers between 1940 and 2021, while the Fast.ai-NLP extracted forty thousand papers from early 1900s to 2023. These extracted papers were finally revised to a concise reading list of a hundred and thirty four papers. Results showed that greater attention has been given to AI-based technologies and models that enhanced production systems. The collective application of AI-based techniques can improve food security and environmental sustainability by optimizing processes to increase yield and aiding in effective monitoring to decrease environmental emissions such as greenhouse gases. The analyzed studies using NLP tools showed how AI technologies could address limitations in the agricultural sector and contribute to improving productivity, resilience to climate change, and food security. Rapid implementation of these technologies in agricultural production systems worldwide has the potential to address challenges such as, resource degradation and depletion, skilled labor shortages, and high input costs. | Usigbe, Member Joy; Asem-Hiablie, Senorpe; Uyeh, Daniel Dooyum; Iyiola, Olayinka; Park, Tusan; Mallipeddi, Rammohan | Kyungpook Natl Univ, Sch Elect Engn, Dept Artificial Intelligence, Daegu 41566, South Korea; Shell Int Explorat & Prod Inc, Biotechnol, Houston, TX USA; Michigan State Univ, Dept Biosyst & Agr Engn, E Lansing, MI USA; Tech Univ Dresden, Dept Hydro Sci & Engn, Dresden, Germany; Kyungpook Natl Univ, Dept Bioind Machinery Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Smart Agr Innovat Ctr, Daegu 41566, South Korea | Park, Tusan/C-2057-2012; Mallipeddi, Rammohan/AAL-5306-2020 | 58512627500; 36656958300; 57194449611; 57810689700; 57202780408; 25639919900 | usigbemember@knu.ac.kr;senorpe.hiablie@shell.com;uyehdani@msu.edu;iyiolaolayinka247@gmail.com;tusan.park@knu.ac.kr;mallipeddi@knu.ac.kr; | ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY | ENVIRON DEV SUSTAIN | 1387-585X | 1573-2975 | 26 | 9 | SCIE | ENVIRONMENTAL SCIENCES;GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | 2024 | 4.2 | 33.3 | 4.64 | 2025-05-07 | 18 | 29 | Artificial intelligence; Food security; Climate-smart agriculture; Controlled environments agriculture; Natural language processing; Autonomous growing | CLIMATE-SMART AGRICULTURE; FEATURE-SELECTION; CROP LOSSES; MANAGEMENT; FRUIT; WEED; CLASSIFICATION | Artificial intelligence; Autonomous growing; Climate-smart agriculture; Controlled environments agriculture; Food security; Natural language processing | agricultural production; artificial intelligence; climate change; food security; skilled labor | English | 2024 | 2024-09 | 10.1007/s10668-023-03588-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Investigation on the electrical and thermal properties of Cr-doped FeSe2 alloys | FeSe 2 is a p -type semiconductor with a narrow band gap, which can be considered a potential thermoelectric material. Herin, the electrical and thermal properties of Cr-doped FeSe 2 , Fe 1-x Cr x Se 2 ( x = 0, 0.03, 0.06, and 0.09), polycrystalline alloys are investigated. All compositions show single-phase marcasite structures of FeSe 2 with gradual decreases in lattice parameters with Cr doping x . With increasing x , the electrical conductivity gradually increases from 13 ( x = 0) to 46 S/cm ( x = 0.09), owing to a large increase in carrier concentration originated from the substitution of Cr 2+ and Cr 3+ at the Fe site. However, the magnitude of Seebeck coefficient decreases considerably at 300 K, resulting in decrease in power factor. In addition, the density-of-state effective mass decreases significantly from 6.0 m 0 - 1.04 m 0 . At 700 K, the decrease in Seebeck coefficient is less severe. Although the total and lattice thermal conductivity decrease at all temperatures owing to additional phonon scattering of the extrinsic Cr ions, a thermoelectric figure of merit, zT , generally decreases compared to that of the pristine sample due to power factor decrease at 300 K. Meanwhile, a slight increase of zT to 0.11 is observed for x = 0.06 at 700 K. | Kang, Seung Min; Roh, Jong Wook; Park, Sanghyun; Park, Joontae; Cho, Hyungyu; Kim, Beomsoo; Kim, Sang-il | Univ Seoul, Dept Mat Sci & Engn, Seoul 02504, South Korea; Kyungpook Natl Univ, Dept Nano & Adv Mat Sci & Engn, Daegu 37224, Gyeongsangbuk D, South Korea | 24765267300; 25638796100; 57191430853; 58686931000; 58182843700; 59151557900; 36171889900 | sang1.kim@uos.ac.kr; | VACUUM | VACUUM | 0042-207X | 1879-2715 | 226 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;PHYSICS, APPLIED | 2024 | 3.9 | 33.4 | 0.78 | 2025-05-07 | 3 | 3 | Thermoelectric; Cr doping; FeSe2 | NANOPARTICLES | Cr doping; FeSe<sub>2</sub>; Thermoelectric | Carrier concentration; Chromium alloys; Electric power factor; Energy gap; Iron alloys; Semiconductor doping; Thermal conductivity; Thermoelectric equipment; Cr-doped; Cr-doping; Narrow bandgap; P type semiconductor; Polycrystalline alloys; Power factors; Single phasis; Thermo-Electric materials; Thermoelectric; Thermoelectric material; Seebeck coefficient | English | 2024 | 2024-08 | 10.1016/j.vacuum.2024.113351 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Eco-friendly electrodeposition sensing of hydrogen peroxide based on Co@Ag/PPy bimetallic nanohybrid | Hydrogen peroxide (H2O2) has practical applications in healthcare, food security, and environmental protection. The current study has been focused on creating H2O2 sensors using a bimetallic composition of polypyrrole/Cobalt-silver on indium tin oxide (ITO) through electrochemical fabrication. Composite hybrid materials comprising Co@Ag/PPy/ITO were successfully synthesized using chronoamperometry and pulsed electrodeposition techniques. The obtained electrode (Co@Ag/PPy/ITO) was studied using scanning electron microscopy (SEM), ultraviolet-visible, and cyclic voltammetry techniques. The energy-dispersive X-ray spectroscopy and SEM revealed that silver and cobalt nanoparticles were distributed on the PPy surface, forming fern-like structures. A detailed investigation of the electrochemical properties of the bimetallic composition was conducted using cyclic voltammetry (CV), chronoamperometry, and electrochemical impedance spectroscopy. The amperometric method and CV were used to carry out the electrochemical detection of H2O2. The non-enzymatic H2O2 sensor exhibited an enhanced amperometry response, showing a higher sensitivity of 3.664 mA mM-1 cm-2 within a linear range spanning 0.12-2.36 mM. Notably, the sensor achieved a low detection limit of 1.985 mu M (S/N = 3). Additionally, the nanocomposite hybrids demonstrated superior stability, repeatability, and reproducibility, making this sensor suitable for long-term use. | Lamiri, Leila; Belgherbi, Ouafia; Tounsi, Assia; Fellah, Mamoun; Atef, Chibani; Sayah, Abdelfetteh; Boumaza, Noureddine; Boudour, Samah; Hamza, Khemliche; Saeed, Mohammad Alam; Avramov, Pavel. V.; El-Hiti, Gamal A. | Res Ctr Ind Technol CRTI, POB 64, Algiers 16014, Algeria; Ferhat Abbas Univ Setif 1, Fac Technol, Dept Proc Engn, Lab Electrochem & Mat, Setif 119000, Algeria; Abbes Laghrour Univ Khenchela, Mech Engn Dept, PO 1252, Khenchela 40004, Algeria; Higher Natl Sch Renewable Energies Environm & Sust, Batna, Algeria; Ferhat Abbas Univ Setif 1, Fac Technol, Dept Proc Engn, Setif 119000, Algeria; Univ Educ, Dept Phys, Div Sci & Technol, Lahore, Pakistan; Kyungpook Natl Univ, Daegu 41566, South Korea; King Saud Univ, Coll Appl Med Sci, Dept Optometry, Riyadh 11433, Saudi Arabia | FELLAH, Mamoun/AFL-5285-2022; El-Hiti, Gamal/I-5942-2013; Abdelfetteh, SAYAH/NAX-5466-2025; Belgherbi, ouafia/HSH-3359-2023; Boudour, Samah/JDD-0305-2023; Lamiri, Leila/HLX-5424-2023 | 54906176900; 57202719438; 57217076578; 55821516400; 57195431062; 57201667653; 26654748100; 57194499833; 59261383500; 35199906500; 7004322420; 7004126373 | lamiri.lila@yahoo.fr;mamoun.fellah@yahoo.fr; | POLYMER BULLETIN | POLYM BULL | 0170-0839 | 1436-2449 | 81 | 17 | SCIE | POLYMER SCIENCE | 2024 | 4 | 33.5 | 0.34 | 2025-05-07 | 3 | 3 | Polypyrrole; Silver nanoparticles; Cobalt nanoparticles; Hydrogen peroxide; Electrochemical sensor | REDUCED GRAPHENE OXIDE; OXYGEN REDUCTION; NANOPARTICLES; SILVER; AU; MICROSPHERES; FABRICATION; MONOLAYER; COMPOSITE | Cobalt nanoparticles; Electrochemical sensor; Hydrogen peroxide; Polypyrrole; Silver nanoparticles | Amperometric sensors; Atomic emission spectroscopy; Corrosion protection; Electrochemical corrosion; Electrochemical electrodes; Electrochemical sensors; Energy dispersive spectroscopy; Hybrid composites; Hydrogen peroxide; Layered semiconductors; Metal nanoparticles; Silver nanoparticles; Silver oxides; 'current; Bimetallic compositions; Bimetallics; Cobalt nanoparticles; Eco-friendly; Electrochemical fabrication; Electrochemicals; Food security; Nanohybrids; Scanning electrons; Cyclic voltammetry | English | 2024 | 2024-11 | 10.1007/s00289-024-05457-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Gulp1 regulates chondrocyte growth arrest and differentiation via the TGF-β/SMAD2/3 pathway | Chondrocyte differentiation is crucial for cartilage formation. However, the complex processes and mechanisms coordinating chondrocyte proliferation and differentiation remain incompletely understood. Here, we report a novel function of the adaptor protein Gulp1 in chondrocyte differentiation. Gulp1 expression is upregulated during chondrogenic differentiation. Gulp1 knockdown in chondrogenic ATDC5 cells reduces the expression of chondrogenic and hypertrophic marker genes during differentiation. Furthermore, Gulp1 knockdown impairs cell growth arrest during chondrocyte differentiation and reduces the expression of the cyclin-dependent kinase inhibitor p21. The activation of the TGF-beta/SMAD2/3 pathway, which is associated with p21 expression in chondrocytes, is impaired in Gulp1 knockdown cells. Collectively, these results demonstrate that Gulp1 contributes to cell growth arrest and chondrocyte differentiation by modulating the TGF-beta/SMAD2/3 pathway. | Kim, Dough; Kim, Jung-Eun; Lee, Seon Bhin; Lee, Na Yeon; Park, Seung-Yoon | Dongguk Univ, Sch Med, Dept Biochem, Gyeongju 38066, South Korea; Kyungpook Natl Univ, Sch Med, Dept Mol Med, Daegu, South Korea | Lee, NaYeon/NOF-5210-2025 | 57204810451; 57209054588; 58973412700; 58974147800; 8627776300 | psyoon@dongguk.ac.kr; | FEBS LETTERS | FEBS LETT | 0014-5793 | 1873-3468 | 598 | 8 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;BIOPHYSICS;CELL BIOLOGY | 2024 | 3 | 33.5 | 0.81 | 2025-05-07 | 2 | 2 | cell growth arrest; chondrocyte; differentiation; Gulp1; p21 | RECEPTOR-RELATED PROTEIN-1; CELL-CYCLE CONTROL; CHONDROGENIC DIFFERENTIATION; APOPTOTIC CELLS; ATDC5 CELLS; ENGULFMENT; MODEL | cell growth arrest; chondrocyte; differentiation; Gulp1; p21 | Adaptor Proteins, Signal Transducing; Cell Differentiation; Cell Proliferation; Chondrocytes; Cyclin-Dependent Kinase Inhibitor p21; adaptor protein; aggrecan; alkaline phosphatase; collagen type 10; collagen type 2; collagen type II alpha 1; collagen type X alpha 1; cyclin dependent kinase inhibitor 1A; Gulp1 protein; Smad2 protein; Smad3 protein; transcription factor Sox9; unclassified drug; cyclin dependent kinase inhibitor 1A; signal transducing adaptor protein; Article; ATDC-5 cell line; cell differentiation; chondrocyte; controlled study; growth inhibition; marker gene; mRNA expression level; protein phosphorylation; Smad signaling; TGF beta signaling; cell differentiation; cell proliferation; genetics; metabolism | English | 2024 | 2024-04 | 10.1002/1873-3468.14862 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Mechanically tunable fluorescence emission and patterned image of a conjugated polymer with an intramolecular stacking structure in an elastomeric silicone rubber matrix | A hybrid film that exhibits reversible fluorescence (FL) is prepared by embedding a conjugated polymer, having an intramolecular stacking structure of the side phenyl rings, in a highly dispersed state into a silicone elastomer. The hybrid film experiences significant FL quenching during stretching and restores its original FL when the external stress is removed. In particular, the hybrid film manufactured using a shadow-masked, plasma-treated silicone elastomer provides a high-resolution FL image, which disappears when the film is stretched and reappears when the external stress is removed. The hybrid film can be applied as a strain-gauge sensor or a security film with embedded images that can be mechanically erased and regenerated. | Han, Dong Cheul; Kim, Heesang; Lee, Chang-Lyoul; Kwak, Giseop | Gumi Elect & Informat Technol Res Inst, Gumi 730853, Gyeongsangbug D, South Korea; Kyungpook Natl Univ, Dept Polymer Sci & Engn, Polymer Nanomat Lab, Sch Appl Chem Engn, 1370 Sankyuk Dong, Deagu 702701, South Korea; Gwangju Inst Sci & Technol, Adv Photon Res Inst, Gwangju 61005, South Korea | 36664568700; 57226091356; 59874887100; 17137322300 | gkwak@knu.ac.kr; | POLYMER BULLETIN | POLYM BULL | 0170-0839 | 1436-2449 | 81 | 18 | SCIE | POLYMER SCIENCE | 2024 | 4 | 33.5 | 0 | 2025-05-07 | 0 | 0 | Conjugated polymers; Fluorescence; Patterned images; Silicone rubber; Stacking structure | SUBSTITUTED ACETYLENE POLYMER; MOLECULAR ROTOR; FILM; ENHANCEMENT; STABILITY | Conjugated polymers; Fluorescence; Patterned images; Silicone rubber; Stacking structure | Conjugated polymers; Plasma applications; Reinforced plastics; Silicon rubber; Silicone rubber; Strain gages; Stretching; Emission images; External stress; Fluorescence emission; Hybrid film; Intramolecular stacking; Patterned image; Silicone elastomers; Silicone rubber; Stacking structures; Tunables; Fluorescence | English | 2024 | 2024-12 | 10.1007/s00289-024-05482-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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