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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | The effectiveness and safety of lenalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma in real-world clinical practice: a study of the Korean Multiple Myeloma Working Party (KMMWP-151 study) | Although lenalidomide plus dexamethasone (RD) is a therapeutic option for relapsed/refractory multiple myeloma (RRMM), limited real-world clinical data exist. The purpose of this study was to estimate efficacy and safety of RD in RRMM patients of the clinical practice. Data from patients at 25 university hospitals in South Korea between October 2009 and December 2016 were collected retrospectively. We report the effectiveness and safety of RD in 546 RRMM patients in routine clinical practice in South Korea. Patients (median age, 65 years) typically received median 7 cycles of RD, and 184 (33.7%) patients were treated with 10 or more cycles of RD. Patients with renal impairment (CLCr = 2; 12.0%), and poor performance status (>= 2; 25.1%) were included. The overall response rate was 64.2%: complete response (13.1%), very good partial response (VGPR 19.9%). With median follow-up duration of 18.6 months, median PFS and OS were 11.2 months and 25.2 months, respectively. In multivariate analysis, less than 2 comorbid conditions, normal LDH, failed one chemotherapy prior to RD, and >= 10 cycles of RD therapy had significantly prolonged PFS (P = 0.007, P = 0.011, P = 0.007, and P < 0.001, respectively). Adverse events were acceptable. RD is effective and safe in real-life clinical practice, including patients with comorbidities. RD is an effective and safe treatment in a real clinical setting which includes patients with comorbidities. Early and continual use of RD treatment may improve RRMM survival outcomes. | Jo, Jae-Cheol; Lee, Ho Sup; Kim, Kihyun; Lee, Je-Jung; Yoon, Sung-Soo; Bang, Soo-Mee; Kim, Jin Seok; Eom, Hyeon-Seok; Yoon, Dok Hyun; Lee, Yoojin; Shin, Ho-Jin; Park, Yong; Lee, Won Sik; Do, Young Rok; Mun, Yeung-Chul; Lee, Mark Hong; Kim, Hyo Jung; Kim, Sung-Hyun; Kim, Min Kyoung; Lim, Sung-Nam; Cho, Su-Hee; Park, Seong Kyu; Yi, Jun Ho; Lee, Jae Hoon; Kim, Jinmi; Min, Chang-Ki | Univ Ulsan, Ulsan Univ Hosp, Dept Hematol & Oncol, Coll Med, Ulsan, South Korea; Kosin Univ, Coll Med, Dept Internal Med, Busan, South Korea; Sungkyunkwan Univ, Sch Med, Dept Med, Samsung Med Ctr, Seoul, South Korea; Chonnam Natl Univ, Dept Hematol Oncol, Hwasun Hosp, Hwasun, Jeollanamdo, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea; Yonsei Univ, Div Hematol, Dept Internal Med, Severance Hosp,Coll Med, Seoul, South Korea; Natl Canc Ctr Korea, Dept Internal Med, Goyang, South Korea; Univ Ulsan, Asan Med Ctr, Dept Oncol, Coll Med, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Hematol Oncol, Daegu, South Korea; Pusan Natl Univ Hosp, Dept Internal Med, Busan, South Korea; Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Busan Paik Hosp, Dept Internal Med, Busan, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Hematooncol, Daegu, South Korea; Ewha Womans Univ, Dept Internal Med, Sch Med, Seoul, South Korea; Konkuk Univ, Dept Internal Med, Div Hematol Oncol, Med Ctr,Sch Med, Seoul, South Korea; Hallym Univ, Dept Internal Med, Coll Med, Sacred Heart Hosp, Anyang, South Korea; Dong A Univ, Dept Internal Med, Dong A Med Ctr, Coll Med, Busan, South Korea; Yeungnam Univ, Coll Med, Dept Med, Daegu, South Korea; Haeundae Baek Hosp, Dept Internal Med, Busan, South Korea; Pusan Natl Univ, Div Hematol Oncol, Dept Internal Med, Yangsan Hosp, Yangsan, South Korea; Soonchunhyang Univ, Dept Hematol Oncol, Bucheon Hosp, Bucheon, South Korea; Chung Ang Univ, Div Hematol Oncol, Dept Med, Seoul, South Korea; Gachon Univ, Gil Hosp, Dept Internal Med, Incheon, South Korea; Pusan Natl Univ Hosp, Dept Biostat, Clin Trial Ctr, Biomed Res Inst, Busan, South Korea; Catholic Univ Korea, Dept Internal Med, Seoul St Marys Hosp, Coll Med, 505 Banpo Dong, Seoul 137701, South Korea | Kim, Jinmi/GLT-0246-2022; Lee, Jung-Hye/F-6974-2013; Yoon, Sung-Soo/J-2773-2012; Kim, Hyo/AAQ-3152-2020; Lee, Jeong/JFA-4725-2023; Yi, Jun Ho/GXZ-8144-2022; KIM, JIN/I-6927-2019; Kim, Kihyun/D-5175-2013; Jo, Jae-Cheol/CAE-9453-2022; Lee, Yoojin/AAB-9799-2022; Kim, Min/ACN-6827-2022 | 35818309200; 57218103550; 57199440300; 7601478211; 7404036304; 7102038069; 55032033600; 35268272400; 25959467800; 57188669696; 16239868400; 7405373234; 55556573100; 8960168300; 7003363716; 55716868500; 7410139194; 56547959500; 57206000629; 24831618100; 56456951500; 57077159400; 24339940900; 56013463700; 57189854813; 57224962914 | ckmin@catholic.ac.kr; | ANNALS OF HEMATOLOGY | ANN HEMATOL | 0939-5555 | 1432-0584 | 99 | 2 | SCIE | HEMATOLOGY | 2020 | 3.673 | 45.4 | 0.33 | 2025-06-25 | 7 | 6 | Multiple myeloma; Lenalidomide plus dexamethasone; Effectiveness; Survival; Real-world evidence | PLUS DEXAMETHASONE; PRIMARY MALIGNANCIES; MAYO STRATIFICATION; FOLLOW-UP; THERAPY; EFFICACY; OUTCOMES; GUIDELINES; RECURRENT; SURVIVAL | Effectiveness; Lenalidomide plus dexamethasone; Multiple myeloma; Real-world evidence; Survival | Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Disease-Free Survival; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Recurrence; Republic of Korea; Survival Rate; dexamethasone; lactate dehydrogenase; lenalidomide; antineoplastic agent; dexamethasone; lenalidomide; adult; adverse event; aged; anemia; anorexia; Article; clinical outcome; clinical practice; comorbidity; constipation; deep vein thrombosis; diarrhea; disease exacerbation; drug efficacy; drug safety; drug withdrawal; dyspnea; electrolyte disturbance; fatigue; febrile neutropenia; female; follow up; heart disease; human; infection; insomnia; kidney failure; kidney injury; liver disease; lung embolism; major clinical study; male; multiple cycle treatment; multiple myeloma; muscle cramp; nausea; neurologic disease; neutropenia; overall survival; peripheral neuropathy; pneumonia; priority journal; progression free survival; rash; relapse; retrospective study; second cancer; sepsis; South Korea; thrombocytopenia; treatment duration; treatment response; clinical trial; disease free survival; epidemiology; middle aged; mortality; multicenter study; multiple myeloma; recurrent disease; survival rate; very elderly | English | 2020 | 2020-02 | 10.1007/s00277-019-03904-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Imaging of COVID-19 pneumonia: Patterns, pathogenesis, and advances | COVID-19 pneumonia is a newly recognized lung infection. Initially, CT imaging was demonstrated to be one of the most sensitive tests for the detection of infection. Currently, with broader availability of polymerase chain reaction for disease diagnosis, CT is mainly used for the identification of complications and other defined clinical indications in hospitalized patients. Nonetheless, radiologists are interpreting lung imaging in unsuspected patients as well as in suspected patients with imaging obtained to rule out other relevant clinical indications. The knowledge of pathological findings is also crucial for imagers to better interpret various imaging findings. Identification of the imaging findings that are commonly seen with the disease is important to diagnose and suggest confirmatory testing in unsuspected cases. Proper precautionary measures will be important in such unsuspected patients to prevent further spread. In addition to understanding the imaging findings for the diagnosis of the disease, it is important to understand the growing set of tools provided by artificial intelligence. The goal of this review is to highlight common imaging findings using illustrative examples, describe the evolution of disease over time, discuss differences in imaging appearance of adult and pediatric patients and review the available literature on quantitative CT for COVID-19. We briefly address the known pathological findings of the COVID-19 lung disease that may help better understand the imaging appearance, and we provide a demonstration of novel display methodologies and artificial intelligence applications serving to support clinical observations. | Nagpal, Prashant; Narayanasamy, Sabarish; Vidholia, Aditi; Guo, Junfeng; Shin, Kyung Min; Lee, Chang Hyun; Hoffman, Eric A. | Univ Iowa, Dept Radiol, Carver Coll Med, Iowa City, IA 52242 USA; Univ Iowa, Dept Pathol, Carver Coll Med, Iowa City, IA 52242 USA; Univ Iowa, Coll Engn, Dept Biomed Engn, Iowa City, IA 52242 USA; Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Radiol, Coll Med, Seoul, South Korea; Univ Iowa, Dept Med, Carver Coll Med, Iowa City, IA 52242 USA | Guo, junfeng/LJK-3575-2024; Lee, Chang-Hoon/AAC-7650-2021; Nagpal, Prashant/T-9989-2019 | 56624233100; 56548551600; 57191378324; 55579979800; 7402410737; 57196253438; 58000586800 | drprashantnagpal@gmail.com; | BRITISH JOURNAL OF RADIOLOGY | BRIT J RADIOL | 0007-1285 | 1748-880X | 93 | 1113 | SCIE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2020 | 3.039 | 45.5 | 1.23 | 2025-06-25 | 26 | 28 | ACUTE RESPIRATORY SYNDROME; QUANTITATIVE COMPUTED-TOMOGRAPHY; ACUTE PULMONARY-EMBOLISM; CT FINDINGS; CHEST CT; LUNG; QUANTIFICATION; CLASSIFICATION; INFECTION; EMPHYSEMA | Betacoronavirus; Coronavirus Infections; Humans; Lung; Pandemics; Pneumonia, Viral; Polymerase Chain Reaction; Tomography, X-Ray Computed; artificial intelligence; child; clinical feature; comparative study; coronavirus disease 2019; disease course; disease severity assessment; hospital patient; human; imaging; lung injury; Middle East respiratory syndrome coronavirus; pathogenesis; pediatric patient; polymerase chain reaction; priority journal; quantitative analysis; radiologist; Review; SARS coronavirus; Betacoronavirus; Coronavirus infection; diagnostic imaging; lung; pandemic; pathology; procedures; virus pneumonia; x-ray computed tomography | English | 2020 | 2020 | 10.1259/bjr.20200538 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Potential image-based criteria of neoadjuvant chemotherapy for colon cancer: multireaders' diagnostic performance | Purpose The objective was to assess which image-based criteria can be best accurately determined at MDCT and which results in least overtreatment. Materials and methods A total of 110 consecutive patients, who underwent curative surgery for colon cancer, were included in this retrospective study. Five radiologists independently assessed the longitudinal diameter of cancer as well as T- and N-categories. The five image-based criteria (T3cd/T4, T3/T4, T3/T4 or N+, T3cd/T4 or N2, and T3/T4 with >= 4 cm) were evaluated in terms of diagnostic accuracy, interreader agreement, and overtreatment risk using pooled receiver-operating curve and Fleiss kappa analyses. Pathologic high-risk stage II or III was used as a reference standard for assessment of overtreatment risk. Results The diagnostic accuracy of multireaders was in the acceptable range (pooled area under curve (AUC): 0.751-0.829). T3/T4 showed the highest AUC (0.829) in terms of diagnostic accuracy. T3/T4 with >= 4 cm showed the highest kappa value (kappa = 0.695) followed by T3/T4 (kappa = 0.623), indicating substantial agreement. The other three criteria revealed moderate agreement (kappa = 0.558-0.577). In terms of overtreatment ratio, T3cd/T4 and T3cd/T4 or N2 showed relatively lower ratios (T3cd/T4, 2.2%; T3cd/T4 or N2, 2.9%), whereas T3/T4 and T3/T4 or N+ revealed higher ratios (T3/T4, 8.7%; T3/T4 or N+, 9.5%). Conclusions T3/T4 was the best criterion in terms of diagnostic accuracy. However, in terms of interreader agreement and overtreatment risk, T3/T4 with >= 4 cm and T3cd/T4 were better as potential image-based criteria of neoadjuvant chemotherapy for colon cancer. | Park, Hyungsik; Cho, Seung Hyun; Kim, Ji Eun; Moon, Sung Kyoung; Park, Byung Geon; Seo, An Na; Kim, See Hyung; Kim, Gab Chul; Ryeom, Hunkyu; Choi, Gyu-Seog | Kyungpook Natl Univ, Sch Med, Chilgok Hosp, Dept Radiol, 807 Hoguk Ro, Daegu 41404, South Korea; Gyeongsang Natl Univ, Coll Med, Dept Radiol, Jinju, South Korea; Kyung Hee Univ Hosp, Dept Radiol, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Chilgok Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiol, Daegu, South Korea; Kyungpook Natl Univ, Med Ctr, Sch Med, Colorectal Canc Ctr, Daegu, South Korea | Kim, Sang-Hyun/J-5402-2012; Kim, JE/M-1512-2013 | 57211532740; 55686242700; 57191681447; 35798730300; 57211532915; 55804153700; 57216511386; 23004499400; 6505864513; 8058759100 | shcho2405@gmail.com; | ABDOMINAL RADIOLOGY | ABDOM RADIOL | 2366-004X | 2366-0058 | 45 | 10 | SCIE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2020 | 3.039 | 45.5 | 0.59 | 2025-06-25 | 7 | 8 | Colon cancer; Multidetector computed tomography (MDCT); Staging; Preoperative chemotherapy; Neoadjuvant chemotherapy | ADJUVANT TREATMENT; STAGE-II; ACCURACY; FLUOROURACIL; OXALIPLATIN; LEUCOVORIN; CETUXIMAB; SURGERY; CT | Colon cancer; Multidetector computed tomography (MDCT); Neoadjuvant chemotherapy; Preoperative chemotherapy; Staging | Colonic Neoplasms; Humans; Neoadjuvant Therapy; Neoplasm Staging; Retrospective Studies; Sensitivity and Specificity; antineoplastic agent; iomeprol; adult; aged; Article; ascending colon; cancer staging; colon cancer; colon resection; controlled study; descending colon; diagnostic accuracy; diagnostic test accuracy study; female; hemicolectomy; histopathology; human; human tissue; longitudinal study; major clinical study; male; multidetector computed tomography; neoadjuvant chemotherapy; priority journal; retrospective study; sensitivity and specificity; sigmoid; transverse colon; tumor volume; colon tumor; diagnostic imaging; neoadjuvant therapy; pathology | English | 2020 | 2020-10 | 10.1007/s00261-019-02243-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Validation of vesical imaging reporting and data system for assessing muscle invasion in bladder tumor | Purpose To retrospectively determine the diagnostic values of vesical imaging reporting and data system (VI-RADS) score for detecting muscle-invasive bladder tumors. Methods This study included 297 consecutive patients with 339 tumors who previously diagnosed and subsequently underwent multiparametric MR imaging between January 2015 and March 2019. Two radiologists assessed the scores of muscleinvasive tumors using cutoff values of >= 4 and >= 3.Cutoff values for VI-RADS scores were estimated from the best operating points of the areas under the receiver operating characteristic curve analyses using the Youden J statistic. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated to assess the utility of VI-RADS for diagnosing muscle-invasive tumors. Results Inter-observer agreement was excellent for three different MR imaging type at lesion level (k = 0.89 for T2W, k = 0.82 for DW, and k = 0.85 for DCE). At a cutoff value of 4, T2W and DW imaging had a diagnostic accuracy of 79.3% (269/339) for tumor lesions with muscle invasion, which was similar to an overall score of 80.2% (272/339). The overall VI-RAD score showed 80.2% accuracy (272/339), with a cutoff value of >= 4, yielding 91.3% sensitivity (85/93), 76.0% specificity (187/246), 83.3% PPV (85/102), and 78.9% NPV (187/237). When we considered an arbitrary overall score of >= 3 as the cutoff value, the accuracy was 63.7% (216/339); sensitivity, 94.6% (125/132); specificity, 43.9% (91/207); PPV, 51.6% (125/242); and NPV, 63.7% (91/97). Conclusion VI-RADS has an overall good performance in the diagnosis of muscle-invasive tumors. | Kim, See Hyung | Kyungpook Natl Univ, Dept Radiol, Kyungpook Natl Univ Hosp, Sch Med, 130 Dongdeok Ro, Daegu 41944, South Korea | Kim, Sang-Hyun/J-5402-2012 | 57216511386 | kimseehyung72@outlook.kr; | ABDOMINAL RADIOLOGY | ABDOM RADIOL | 2366-004X | 2366-0058 | 45 | 2 | SCIE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2020 | 3.039 | 45.5 | 4.63 | 2025-06-25 | 57 | 56 | Multiparametric MRI; Bladder tumor; Vesical imaging reporting; Data system (VI-RADS) | CANCER; MRI; ACCURACY; STAGE | Bladder tumor; Data system (VI-RADS); Multiparametric MRI; Vesical imaging reporting | Aged; Contrast Media; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Muscle Neoplasms; Muscle, Smooth; Neoplasm Invasiveness; Neoplasm Staging; Organometallic Compounds; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Urinary Bladder Neoplasms; gadobutrol; contrast medium; gadobutrol; organometallic compound; adult; aged; Article; cancer diagnosis; cancer staging; cancer surgery; controlled study; cystectomy; diagnostic value; female; human; interrater reliability; major clinical study; male; multiparametric magnetic resonance imaging; muscle invasive bladder cancer; predictive value; priority journal; radiological parameters; radiologist; receiver operating characteristic; retrospective study; tumor invasion; vesical imaging reporting and data system score; bladder tumor; diagnostic imaging; middle aged; muscle tumor; nuclear magnetic resonance imaging; pathology; procedures; sensitivity and specificity; smooth muscle; tumor invasion | English | 2020 | 2020-02 | 10.1007/s00261-019-02190-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Meeting Abstract | Association of antipsychotic medications with seizure in children and adolescent | Jeon, Soo Min; Park, Susan; Park, Hae-Young; An, Sena; Kwon, Jin-Won | Kyungpook Natl Univ, Coll Pharm, Daegu, South Korea; Kyungpook Natl Univ, Pharmaceut Sci Res Inst, Daegu, South Korea | Park, Susan/JRY-5671-2023 | PHARMACOEPIDEMIOLOGY AND DRUG SAFETY | PHARMACOEPIDEM DR S | 1053-8569 | 1099-1557 | 29 | SCIE | PHARMACOLOGY & PHARMACY;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 2.89 | 45.6 | 0 | English | 2020 | 2020-10 | 바로가기 | 바로가기 | ||||||||||||||||
| ○ | ○ | Article | Effects of Hemicastration on Testes and Testosterone Concentration in Stallions | The endocrine system is critical to the maintenance of testicular function. The homeostasis of sex hormone levels is orchestrated by positive and negative feedback systems controlled by the hypothalamic-pituitary-gonadal axis. This study investigated the long-term effects of hemicastration on testicular size and function in stallions. Four Thoroughbred stallions, 4-6 years of age, were included in this study. Several parameters, including testicular weight and volume, plasma testosterone concentrations, VASA-positive germ cell populations and cross-sectional areas of the seminiferous tubules were compared in stallions that underwent two hemicastrations, approximately 11 months apart. The weights and volumes of testes harvested at the second hemicastration were significantly higher than those of testes collected at the first hemicastration. However, VASA-positive germ cell populations and the cross-sectional areas of seminiferous tubules were not significantly different between testes harvested at the first and second hemicastrations. Similarly, plasma testosterone concentrations measured weekly for 3 weeks before the first hemicastration, 3 weeks after the first hemicastration, and 3 weeks before the second hemicastration were not significantly different. Our results suggest that hemicastration results in compensatory enlargement of the remaining testis and compensatory steroidogenesis to maintain normal reproductive function in stallions. (C) 2020 Elsevier Inc. All rights reserved. | Jung, Heejun; Lee, Geumhui; Kim, Junyoung; Lee, Jang-Won; Yoon, Minjung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju, South Korea; Sejong Univ, Dept Integrated Bioind, 209 Neungdong Ro, Seoul 05006, South Korea; Kyungpook Natl Univ, Dept Horse Compan & Wild Anim Sci, Sangju, South Korea | 56374279800; 57191860695; 57218494918; 56117978100; 22137296500 | wintrelove@sejong.ac.kr;mjyoonemail@gmail.com; | JOURNAL OF EQUINE VETERINARY SCIENCE | J EQUINE VET SCI | 0737-0806 | 1542-7412 | 92 | SCIE | VETERINARY SCIENCES | 2020 | 1.583 | 45.6 | 0.38 | 2025-06-25 | 6 | 5 | Hemi-castration; Stallion; Testis; Testosterone; Germ cells | SERTOLI-CELLS; COMPENSATORY HYPERTROPHY; LUTEINIZING-HORMONE; PROLIFERATION; CASTRATION | Germ cells; Hemi-castration; Stallion; Testis; Testosterone | Animals; Horses; Male; Seminiferous Tubules; Testis; Testosterone; testosterone; testosterone; Article; castration; germ cell; hemicastration; male; male infertility; nonhuman; seminiferous tubule; spermatogenesis; stallion; steroidogenesis; subfertility; testis function; testis size; testis weight; testosterone blood level; Thoroughbred horse; animal; horse; testis | English | 2020 | 2020-09 | 10.1016/j.jevs.2020.103166 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | Article | A Subnormal Completion Problem for Weighted Shifts on Directed Trees, II | The subnormal completion problem on a directed tree is to determine, given a collection of weights on a subtree, whether the weights may be completed to the weights of a subnormal weighted shift on the directed tree. We study this problem on a directed tree with a single branching point, η branches and the trunk of length 1 and its subtree which is the “truncation” of the full tree to vertices of generation not exceeding 2. We provide necessary and sufficient conditions written in terms of two parameter sequences for the existence of a subnormal completion in which the resulting measures are 2-atomic. As a consequence, we obtain a solution of the subnormal completion problem for this pair of directed trees when η< ∞. If η= 2 , we present a solution written explicitly in terms of initial data. © 2020, The Author(s). | Exner, George R.; Jung, Il Bong; Stochel, Jan; Yun, Hye Yeong | Department of Mathematics, Bucknell University, Lewisburg, 17837, PA, United States; Department of Mathematics, Kyungpook National University, Daegu, 41566, South Korea; Instytut Matematyki, Uniwersytet Jagielloński, ul. Łojasiewicza 6, Kraków, 30348, Poland; Department of Mathematics, Kyungpook National University, Daegu, 41566, South Korea | 7004560697; 7102964485; 6602273956; 55926996500 | Jan.Stochel@im.uj.edu.pl; | Integral Equations and Operator Theory | INTEGR EQUAT OPER TH | 0378-620X | 1420-8989 | 92 | 1 | SCIE | MATHEMATICS | 2020 | 1.016 | 45.9 | 0.23 | 2025-06-25 | 3 | 2-Atomic measures; Subnormal completion problem; Subnormal operator; Weighted shift on a directed tree | English | Final | 2020 | 10.1007/s00020-020-2565-8 | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Review | 2020 Korean Society of Myocardial Infarction Expert Consensus Document on Pharmacotherapy for Acute Myocardial Infarction | Clinical practice guidelines published by the European Society of Cardiology and the American College of Cardiology/American Heart Association summarize the available evidence and provide recommendations for health professionals to enable appropriate clinical decisions and improve clinical outcomes for patients with acute myocardial infarction (AMI). However, most current guidelines are based on studies in non-Asian populations in the pre-percutaneous coronary intervention (PCI) era. The Korea Acute Myocardial Infarction Registry is the first nationwide registry to document many aspects of AMI from baseline characteristics to treatment strategies. There are well-organized ongoing and published randomized control trials especially for antiplatelet therapy among Korean patients with AMI. Here, members of the Task Force of the Korean Society of Myocardial Infarction review recent published studies during the current PCI era, and have summarized the expert consensus for the pharmacotherapy of AMI. | Kim, Hyun Kuk; Ahn, Youngkeun; Chang, Kiyuk; Jeong, Young-Hoon; Hahn, Joo-Yong; Choo, Eun Ho; Kim, Min Chul; Kim, Hyo-Soo; Kim, Weon; Cho, Myeong-Chan; Jang, Yangsoo; Kim, Chong Jin; Jeong, Myung Ho; Chae, Shung Chull | Chosun Univ, Dept Internal Med, Coll Med, Gwangju, South Korea; Chonnam Natl Univ Hosp, Dept Cardiol, 42 Jebong Ro, Gwangju 61469, South Korea; Catholic Univ Korea, Dept Internal Med, Div Cardiol, Seoul St Marys Hosp, Seoul, South Korea; Gyeongsang Natl Univ, Sch Med, Dept Internal Med, Chang Won, South Korea; Gyeongsang Natl Univ, Cardiovasc Ctr, Changwon Hosp, Chang Won, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Heart Vasc & Stroke Inst, Sch Med, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Div Cardiol, Seoul, South Korea; Seoul Natl Univ Hosp, Cardiovasc Ctr, Seoul, South Korea; Kyung Hee Univ, Kyung Hee Univ Hosp, Dept Internal Med, Div Cardiovasc, Seoul, South Korea; Chungbuk Natl Univ, Coll Med, Dept Internal Med, Cheongju, South Korea; Yonsei Univ, Cardiovasc Res Inst, Cardiol Div, Coll Med, Seoul, South Korea; Kyung Hee Univ Hosp Gangdong, Cardiovasc Ctr, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea | Kim, Min Chul/IYJ-9897-2023; Choo, Eun Ho/HCH-6246-2022; Jeong, Young-Hoon/F-3476-2015; Hahn, Joo-Yong/AAU-7250-2020; Kim, Jin Sug/AAY-6890-2021; Kim, Hyo/J-2753-2012; Jang, Yang/D-4803-2012 | 57206210646; 56937721300; 25521288100; 24758957500; 12771661800; 57772069800; 57202224572; 33567809200; 8570166100; 7401727518; 55429942500; 35229511500; 56485157500; 7101962036 | myungho@chollian.net;scchae@knu.ac.kr; | KOREAN CIRCULATION JOURNAL | KOREAN CIRC J | 1738-5520 | 1738-5555 | 50 | 10 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 3.243 | 46.1 | 0.41 | 2025-06-25 | 22 | 20 | Myocardial infarction; Drug therapy | ST-SEGMENT-ELEVATION; PERCUTANEOUS CORONARY INTERVENTION; DUAL ANTIPLATELET THERAPY; CONVERTING ENZYME-INHIBITORS; TYPE-1 RECEPTOR BLOCKERS; STATIN THERAPY; UNFRACTIONATED HEPARIN; CARDIOVASCULAR EVENTS; FIBRINOLYTIC THERAPY; PRIMARY ANGIOPLASTY | Myocardial infarction; Drug therapy | antifibrinolytic agent; antilipemic agent; beta adrenergic receptor blocking agent; acute heart infarction; clinical decision making; consensus; fibrinolytic therapy; human; Korea; maintenance therapy; medical society; non ST segment elevation myocardial infarction; practice guideline; renin angiotensin aldosterone system; Review; ST segment elevation myocardial infarction | English | 2020 | 2020-10 | 10.4070/kcj.2020.0196 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A Close Relationship between Non-Alcoholic Fatty Liver Disease Marker and New-Onset Hypertension in Healthy Korean Adults | Background and Objectives: Nonalcoholic fatty liver disease (NAFLD) is an excessive accumulation of fat into the liver as a result of increased inflammation and insulin resistance. Although there can be common pathogenic mechanisms for NAFLD and hypertension associated with the development of cardiovascular diseases, little data are showing the association between NAFLD and hypertension in a large-scale cohort study. Thus, we evaluated the ability of the fatty liver index (FLI), a surrogate marker of NAFLD, to predict the development of hypertension in healthy individuals. Methods: We included 334,280 healthy individuals without known comorbidities who underwent the National Health check-ups in South Korea from 2009 to 2014. The association between the FLI and hypertension was analyzed using multivariate Cox proportional-hazards models. Results: During a median of 5.2 years' follow-up, 24,678 subjects (7.4%) had new-onset hypertension. We categorized total subjects into quartile groups according to FLI (range: Q1, 0-4.9; Q2, 5.0-125; Q3, 12.6-31.0; and Q4, >31.0). The incidence of hypertension was higher in subjects with the highest FLI than in those with the lowest FLI (Q4, 9,968 [11.9%] vs. Q1, 2,277 [2.7%]; p<0.001). There was a significant correlation between the highest FLI and an increased risk of new-onset hypertension (adjusted hazard ratio between Q4 and Q1, 2.330; 95% confidence interval, 2.218-2.448; p<0.001). FLI was significantly associated with an increased risk of new-onset hypertension regardless of baseline characteristics. Conclusions: Higher FLI was independently associated with increased risk of hypertension in a healthy Korean population. | Roh, Jae-Hyung; Park, Jae-Hyeong; Lee, Hanbyul; Yoon, Yong-Hoon; Kim, Minsu; Kim, Yong-Giun; Park, Gyung-Min; Lee, Jae-Hwan; Seong, In-Whan | Chungnam Natl Univ, Chungnam Natl Univ Hosp, Dept Cardiol Internal Med, Sch Med, 282 Munhwa Ro, Daejeon 35015, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Cardiol, Coll Med, Ulsan, South Korea | Park, Jae-Hyeong/AAD-9015-2021; Lee, Yoon/ABA-8808-2020; Park, M.J./Y-5611-2019 | 57216309871; 36063048400; 59107079300; 56038479700; 57208554686; 57207444006; 25924423800; 36066387900; 35254371300 | jaehpark@cnu.ac.kr; | KOREAN CIRCULATION JOURNAL | KOREAN CIRC J | 1738-5520 | 1738-5555 | 50 | 8 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 3.243 | 46.1 | 0.89 | 2025-06-25 | 15 | 16 | Fatty liver; nonalcoholic; Hypertension; Healthy people programs | CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME; HEPATIC STEATOSIS; FIBROSIS; INSULIN; ASSOCIATION; DYSFUNCTION; MANAGEMENT; OBESITY; RISK | Fatty liver; Healthy people programs; Hypertension; Nonalcoholic | adult; aged; Article; cardiovascular risk; cohort analysis; comorbidity; correlational study; disease association; disease marker; fatty liver index; female; follow up; human; hypertension; major clinical study; male; middle aged; nonalcoholic fatty liver; South Korea | English | 2020 | 2020-08 | 10.4070/kcj.2019.0379 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clopidogrel versus Aspirin after Dual Antiplatelet Therapy in Acute Myocardial Infarction Patients Undergoing Drug-Eluting Stenting | Background and Objectives: There is a paucity of data regarding the benefit of clopidogrel monotherapy after dual antiplatelet therapy (DAPT) in patients treated with drug-eluting stents (DES). This study compared outcome between clopidogrel versus aspirin as monotherapy after DES for acute myocardial infarction (MI). Methods: From Korea Acute Myocardial Infarction Registry-National Institute of Health database, 1,819 patients treated with DES who were switched to monotherapy with clopidogrel (n=534) or aspirin (n=1,285) after uneventful 12-month DAPT were analyzed. The primary endpoint was net adverse clinical events (NACE), defined as a composite of death from any cause, MI, repeat percutaneous coronary intervention (PCI), stent thrombosis, ischemic stroke, or major bleeding during the period from 12 to 24 months. Results: After adjustment using inverse probability of treatment weighting, patients who received clopidogrel, compared with those treated with aspirin, had a similar incidence of NACE (0.7% and 0.7%; hazard ratio, 1.06; 95% confidence interval, 0.31-3.60; p=0.923). The 2 groups had similar rates of death from any cause (0.1% in each group, p=0.789), MI (0.3% and 0.1%, respectively; p=0.226), repeat PCI (0.1% and 0.3%, respectively; p=0.548), stent thrombosis (0.1% and 0%, respectively; p=0.121), major bleeding (0.2% in each group, p=0.974), and major adverse cardiovascular and cerebrovascular events (0.5% in each group, p=0.924). Conclusions: Monotherapy with clopidogrel, compared to aspirin, after DAPT showed similar clinical outcomes in patients with acute MI treated with DES. | Sim, Doo Sun; Jeong, Myung Ho; Kim, Hyo Soo; Gwon, Hyeon Cheol; Seung, Ki Bae; Rha, Seung Woon; Chae, Shung Chull; Kim, Chong Jin; Cha, Kwang Soo; Park, Jong Seon; Yoon, Jung Han; Chae, Jei Keon; Joo, Seung Jae; Choi, Dong Ju; Hur, Seung Ho; Seong, In Whan; Cho, Myeong Chan; Kim, Doo Il; Oh, Seok Kyu; Ahn, Tae Hoon; Hwang, Jin Yong | Chonnam Natl Univ Hosp, Dept Cardiovasc Med, 42 Jebong Ro, Gwangju 61469, South Korea; Seoul Natl Univ Hosp, Dept Cardiol, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Cardiol, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Cardiol, Seoul, South Korea; Korea Univ, Cardiovasc Ctr, Guro Hosp, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Cardiol, Daegu, South Korea; Kyung Hee Univ Hosp Gangdong, Dept Cardiol, Seoul, South Korea; Pusan Natl Univ Hosp, Dept Cardiol, Busan, South Korea; Yeungnam Univ Hosp, Div Cardiol, Daegu, South Korea; Yonsei Univ, Wonju Severance Christian Hosp, Div Cardiol, Wonju Coll Med, Wonju, South Korea; Chunbuk Natl Univ Hosp, Dept Cardiol, Jeonju, South Korea; Jeju Natl Univ Hosp, Dept Cardiol, Jeju, South Korea; Seoul Natl Univ, Cardiovasc Ctr, Bundang Hosp, Seongnam, South Korea; Keimyung Univ, Dept Cardiol, Dongsan Med Ctr, Daegu, South Korea; Chungnam Natl Univ Hosp, Dept Cardiol, Daejeon, South Korea; Chungbuk Natl Univ Hosp, Dept Cardiol, Cheongju, South Korea; Inje Univ, Dept Cardiol, Haeundae Paik Hosp, Busan, South Korea; Wonkwang Univ Hosp, Dept Cardiol, Iksan, South Korea; Gachon Univ, Dept Cardiol, Gil Med Ctr, Incheon, South Korea; Kyungsang Natl Univ Hosp, Dept Cardiol, Jinju, South Korea | Choi, Dong-Ju/J-5686-2012; Kim, Hyo/J-2753-2012; Kim, Jin Sug/AAY-6890-2021; Kim, Mi Jin/GXH-9639-2022; Rha, Seung-Woon/AGE-5810-2022; Jeong, Young-Hoon/F-3476-2015; 안, 태훈/GON-9067-2022; Han, Jae-Young/AAV-1100-2021 | 7006825347; 56485157500; 33567809200; 6603262426; 7003964208; 8569030400; 7101962036; 35229511500; 7102837700; 15763054600; 35760728900; 26029709000; 9236504200; 35274349200; 34570274500; 35254371300; 7401727518; 8635545900; 24734336000; 57202554645; 55892914700 | myungho@chollian.net; | KOREAN CIRCULATION JOURNAL | KOREAN CIRC J | 1738-5520 | 1738-5555 | 50 | 2 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 3.243 | 46.1 | 1.04 | 2025-06-25 | 15 | 19 | Antiplatelet agents; Drug-eluting stents; Myocardial infarction | PROPENSITY SCORE; FOCUSED UPDATE; VALIDATION; DISEASE; TRIALS; RISK | Antiplatelet agents; Drug-eluting stents; Myocardial infarction | acetylsalicylic acid; biological marker; clopidogrel; creatine kinase MB; prasugrel; ticagrelor; troponin I; troponin T; acute heart infarction; adult; Article; brain ischemia; cardiac patient; clinical outcome; comparative effectiveness; disease duration; drug efficacy; drug safety; dual antiplatelet therapy; female; follow up; heart infarction; human; incidence; loading drug dose; major clinical study; male; middle aged; monotherapy; outcome assessment; patient; percutaneous coronary intervention; practice guideline; prospective study; ST segment; stent thrombosis; target vessel revascularization; tertiary care center; thrombolysis in myocardial infarction; thrombolysis in myocardial infarction; treatment duration | English | 2020 | 2020-02 | 10.4070/kcj.2019.0166 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Consensus Statement on Coronary Intervention during the Coronavirus Disease 2019 (COVID-19) Pandemic: from the Korean Society of Interventional Cardiology (KSIC) | Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the novel virus severe acute respiratory syndrome coronavirus-2. The first case developed in December, 2019 in Wuhan, China; several months later, COVID-19 has become pandemic, and there is no end in sight. This disaster is also causing serious health problems in the area of cardiovascular intervention. In response, the Korean Society of Interventional Cardiology formed a COVID-19 task force to develop practice guidelines. This special article introduces clinical practice guidelines to prevent secondary transmission of COVID-19 within facilities; the guidelines were developed to protect patients and healthcare workers from this highly contagious virus. We hope these guidelines help healthcare workers and cardiovascular disease patients around the world cope with the COVID-19 pandemic. | Lee, Kwan Yong; Lee, Bong-Ki; Kim, Won-Jang; Kang, Se Hun; Park, Taek Kyu; Kim, Song-Yi; Suh, Jung-Won; Yoon, Chang-Hwan; Yang, Dong Heon; Ryu, Sung Kee; Kim, Sang-Hyun; Lee, Sung Yun; Chae, In-Ho | Catholic Univ Korea, Dept Cardiol, Incheon St Marys Hosp, Incheon, South Korea; Kangwon Natl Univ, Kangwon Natl Univ Hosp, Dept Internal Med, Div Cardiol,Sch Med, Chunchon, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Cardiol, Sch Med, Seongnam, South Korea; Sungkyunkwan Univ, Heart Vasc & Stroke Inst, Samsung Med Ctr, Div Cardiol,Dept Med,Sch Med, Seoul, South Korea; Jeju Natl Univ, Jeju Natl Univ Hosp, Dept Internal Med, Div Cardiol,Sch Med, Jeju, South Korea; Seoul Natl Univ, Cardiovasc Ctr, Bundang Hosp, 82 Gumi Ro 173 Beon Gil, Seongnam 13620, South Korea; Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Div Cardiol, Daegu, South Korea; Eulji Univ, Nowon Eulji Med Ctr, Div Cardiol, Seoul, South Korea; Seoul Natl Univ, Seoul Boramae Hosp, Div Cardiol, Coll Med, Seoul, South Korea; Inje Univ, Cardiac & Vasc Ctr, Ilsan Paik Hosp, Goyang, South Korea | Kim, Sang-Hyun/J-5402-2012; Kang, Se Hun/HDO-2406-2022; Kim, Song-Yi/JAC-5358-2023; Chae, In-Ho/J-5682-2012; Yoon, Changhwan/MXM-0567-2025 | 57203317356; 7405442104; 37070117400; 25421794000; 55750570800; 35740671300; 35273808100; 7202882965; 35277423400; 15736269700; 49663680000; 25623542700; 35274374100 | ihchae@snu.ac.kr; | KOREAN CIRCULATION JOURNAL | KOREAN CIRC J | 1738-5520 | 1738-5555 | 50 | 11 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 3.243 | 46.1 | 0.07 | 2025-06-25 | 1 | 1 | COVID-19; Cardiovascular diseases; Coronary angiography; Percutaneous coronary intervention; Practice guideline | PNEUMONIA; WUHAN | Cardiovascular diseases; Coronary angiography; COVID-19; Percutaneous coronary intervention; Practice guideline | air conditioning; Article; cardiogenic shock; cardiovascular disease; coronary angiography; coronavirus disease 2019; COVID-19 testing; disinfection; emergency health service; health care personnel; heart arrest; human; intubation; lockdown; medical society; non st segment elevation acute coronary syndrome; pandemic; patient safety; patient transport; percutaneous coronary intervention; practice guideline; resuscitation; ST segment elevation myocardial infarction; virus transmission | English | 2020 | 2020-11 | 10.4070/kcj.2020.0283 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Inhibition of Smooth Muscle Cell Proliferation and Migration by a Talin Modulator Attenuates Neointimal Formation after Femoral Arterial Injury | Background and Objectives: Vascular smooth muscle cell (SMC) proliferation and migration play a critical role in neointimal formation. Focal adhesion is involved in cell proliferation and migration, and talin is known to be a key regulator of these processes. We synthesized a new talin modulator that binds to the talin protein, and investigated its effects on SMCs and neointimal formation after vascular injury. Methods: Human aortic SMCs (HAoSMCs) were treated with a newly synthesized talin modulator. Apolipoprotein E knockout (ApoE KO) mice were subjected to left femoral arterial injury and orally administered with the talin modulator daily. Laser Doppler imager was used to compare the blood flow, and injured femoral arteries and blood serum were analyzed after 28 days. Results: The talin modulator significantly inhibited cell proliferation in a concentration-dependent manner and suppressed the migration of HAoSMCs. Treatment with a talin modulator resulted in a significant reduction in the phosphorylation of focal adhesion molecules and downstream signaling molecules related to cell proliferation and migration. The effects of the talin modulator in HAoSMCs were found to be reversible, as evidenced by the reactivation of signaling pathways upon its removal. After 28 days of administration of the talin modulator, an improvement in the blood flow and reduction in neointimal formation in the injured femoral arteries were observed. Conclusions: We demonstrated the inhibitory effects of a talin modulator on SMC proliferation and migration, and that were associated with downregulation of signaling pathways, resulting in the attenuation of neointimal formation in ApoE KO mice. | Lim, I-Rang; Kim, Chungho; Jung, Jong-Wha; Kim, Jong-Ho; Hong, Soon Jun | Korea Univ, Dept Cardiol, Cardiovasc Ctr, Coll Med, 73 Goryeodae Ro, Seoul 02841, South Korea; Korea Univ, Dept Life Sci, Coll Life Sci & Biotechnol, Seoul, South Korea; Kyungpook Natl Univ, Pharmaceut Sci Res Inst, Coll Pharm, Daegu, South Korea | 57218259868; 7409874548; 26032128600; 57218358711; 25648124100 | mecey@naver.com;psyche94@hanmail.net; | KOREAN CIRCULATION JOURNAL | KOREAN CIRC J | 1738-5520 | 1738-5555 | 50 | 7 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 3.243 | 46.1 | 0.22 | 2025-06-25 | 4 | 4 | Talin; Focal adhesion; Vascular smooth muscle cell; Vascular injury; Neointima formation | FOCAL ADHESION KINASE; ACTIVATION; SURVIVAL | Focal adhesion; Neointima formation; Talin; Vascular injury; Vascular smooth muscle cell | alpha smooth muscle actin; apolipoprotein E; cardiovascular agent; focal adhesion kinase; integrin; interleukin 6; mitogen activated protein kinase 1; mitogen activated protein kinase 3; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; n [(4 bromo 3 methoxyphenyl)carbamoyl] 2 (2 methoxyphenoxy)acetamide; paxillin; protein kinase B; talin; tumor necrosis factor; unclassified drug; vinculin; animal experiment; animal model; antiproliferative activity; artery injury; Article; blood analysis; controlled study; drug protein binding; enzyme linked immunosorbent assay; femoral artery; femoral artery flow; human; human cell; immunofluorescence; in vitro study; knockout mouse; laser Doppler flowmetry; male; migration inhibition; mouse; neointima; nonhuman; protein phosphorylation; signal transduction; vascular smooth muscle cell; Western blotting | English | 2020 | 2020-07 | 10.4070/kcj.2019.0421 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | One-Year Clinical Outcomes between Single- versus Multi-Staged PCI for ST Elevation Myocardial Infarction with Multi-Vessel Coronary Artery Disease: from Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) | Background and Objectives: Although complete revascularization is known superior to incomplete revascularization in ST elevation myocardial infarction (STEMI) patients with multi-vessel coronary artery disease (MVCD), there are no definite instructions on the optimal timing of non-culprit lesions percutaneous coronary intervention (PCI). We compared 1-year clinical outcomes between 2 different complete multi-vessel revascularization strategies. Methods: From the Korea Acute Myocardial Infarction Registry-National Institute of Health, 606 patients with STEMI and MVCD who underwent complete revascularization were enrolled from November 2011 to December 2015. The patients were assigned to multi-vessel single-staged PCI (SS PCI) group (n=254) or multi-vessel multi-staged PCI (MS PCI) group (n=352). Propensity score matched 1-year clinical outcomes were compared between the groups. Results: At one year, MS PCI showed a significantly lower rate of all-cause mortality (hazard ratio [HR], 0.42; 95% CI, 0.19-0.92; p=0.030) compared with SS PCI. In subgroup analysis, all-cause mortality increased in SS PCI with cardiogenic shock (HR, 4.60; 95% CI, 1.54-13.77; p=0.006), age >= 65 years (HR, 4.00; 95% CI, 1.67-9.58, p=0.002), Killip class III/IV (HR, 7.32; 95% CI, 1.68-31.87; p=0.008), and creatinine clearance <= 60 mL/min (HR, 2.81; 95% CI, 1.10-7.18; p=0.031). After propensity score-matching, MS PCI showed a significantly lower risk of major adverse cardiovascular event than SS PCI. Conclusions: SS PCI was associated with worse clinical outcomes compared with MS PCI. MS PCI for non-infarct-related artery could be a better option for patients with STEMI and MVCD, especially high-risk patients. | Ahn, Kye Taek; Oh, Jin Kyung; Seong, Seok-Woo; Jin, Seon-Ah; Lee, Jae-Hwan; Choi, Si Wan; Jeong, Myung Ho; Chae, Shung Chull; Kim, Young Jo; Kim, Chong Jin; Kim, Hyo-Soo; Cho, Myeong Chan; Gwon, Hyeon Cheol; Jeong, Jin-Ok; Seong, In-Whan | Chungnam Natl Univ, Chungnam Natl Univ Hosp, Dept Internal Med, Div Cardiol,Coll Med, 282 Munhwa Ro, Daejeon 35015, South Korea; Chonnam Natl Univ Hosp, Dept Internal Med, Div Cardiol, Gwangju, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Cardiol, Daegu, South Korea; Yeungnam Univ Hosp, Dept Internal Med, Div Cardiol, Daegu, South Korea; Kyung Hee Univ, Dept Internal Med, Div Cardiol, Coll Med, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Div Cardiol, Seoul, South Korea; Chungbuk Natl Univ Hosp, Dept Internal Med, Div Cardiol, Cheongju, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Div Cardiol,Dept Internal Med, Seoul, South Korea | Cho, Young-Seok/J-5670-2012; Lee, Yoon/ABA-8808-2020; Kim, Hyo/J-2753-2012; Kim, Jin Sug/AAY-6890-2021 | 24597483100; 57201838346; 54791421600; 55358593200; 36066387900; 57208291768; 56485157500; 7101962036; 57189907572; 35229511500; 33567809200; 7401727518; 6603262426; 57210973601; 35254371300 | jojeong@cnu.ac.kr; | KOREAN CIRCULATION JOURNAL | KOREAN CIRC J | 1738-5520 | 1738-5555 | 50 | 3 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 3.243 | 46.1 | 0.37 | 2025-06-25 | 7 | 9 | Myocardial infarction; Percutaneous coronary intervention; Myocardial revascularization; Coronary artery disease | SEGMENT ELEVATION; MULTIVESSEL DISEASE; RANDOMIZED-TRIAL; COMPLETE REVASCULARIZATION; STENT THROMBOSIS; CULPRIT LESION; INTERVENTION; ANGIOPLASTY; MANAGEMENT; IMPACT | Coronary artery disease; Myocardial infarction; Myocardial revascularization; Percutaneous coronary intervention | beta adrenergic receptor blocking agent; creatinine; fibrinogen receptor antagonist; hydroxymethylglutaryl coenzyme A reductase inhibitor; age; aged; all cause mortality; Article; cardiogenic shock; cardiovascular risk; clinical outcome; coronary angiography; coronary artery disease; creatinine clearance; diabetes mellitus; disease severity; dyslipidemia; female; follow up; heart death; human; hypertension; left ventricular systolic dysfunction; major clinical study; male; percutaneous coronary intervention; ST segment elevation myocardial infarction; target vessel revascularization | English | 2020 | 2020-03 | 10.4070/kcj.2019.0176 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Role of Carotid Artery Stenting in Prevention of Stroke for Asymptomatic Carotid Stenosis: Bayesian Cross-Design and Network Meta-Analyses | Background and Objectives: There is insufficient evidence regarding the optimal treatment for asymptomatic carotid stenosis. Methods: Bayesian cross-design and network meta-analyses were performed to compare the safety and efficacy among carotid artery stenting (CAS), carotid endarterectomy (CEA), and medical treatment (MT). We identified 18 studies (4 randomized controlled trials (RCTs) and 14 nonrandomized, comparative studies (NRCSs)) comparing CAS with CEA, and 4 RCT5 comparing CEA with MT from MEDLINE, Cochrane Library, and Embase databases. Results: The risk for periprocedural stroke tended to increase in CAS, compared to CEA (odds ratio (OR), 1.86; 95% credible interval [CrI], 0.62-4.54). However, estimates for periprocedural myocardial infarction (MI) were quite heterogeneous in RCTs and NRCSs. Despite a trend of decreased risk with CAS in RCT5 (OR, 0.70; 95% CrI, 0.27-1.24), the risk was similar in NRCSs (OR, 1.02; 95% CrI, 0.87-1.18). In indirect comparisons of MT and CAS, MT showed a tendency to have a higher risk for the composite of periprocedural death, stroke, MI, or nonperiprocedural ipsilateral stroke (OR, 1.30; 95% CrI, 0.74-2.73). Analyses of study characteristics showed that CEA-versus-MT studies took place about 10-year earlier than CEA-versus-CAS studies. Conclusions: A similar risk for periprocedural MI between CEA and CAS in NRCSs suggested that concerns about periprocedural MI accompanied by CEA might not matter in real-world practice when preoperative evaluation and management are working. Maybe the benefits of CAS over MT have been overestimated considering advances in medical therapy within10-year gap between CEA-versus-MT and CEA-versus-CAS studies. | Roh, Jae Hyung; Cho, Hyun Jun; Lee, Jae Hwan; Kim, Yongku; Park, Yeongwoo; Park, Jae Hyeong; Park, Hee Soon; Kim, Minsu; Jin, Hyang Gon; Cheon, Yeji; Seong, In Whan | Korea Univ Med Ctr Anam Hosp, Dept Internal Med, Div Cardiol, Korea, Seoul, South Korea; Chungnam Natl Univ, Chungnam Natl Univ Hosp, Sch Med, Dept Cardiol Internal Med, 282 Munhwa Ro, Daejeon 35015, South Korea; Daegu Fatima Hosp, Dept Cardiol, Daegu, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Korea Univ, Dept Internal Med, Div Cardiol, Med Ctr,Anam Hosp, Seoul, South Korea | ; Park, Jae-Hyeong/AAD-9015-2021; Lee, Yoon/ABA-8808-2020 | 57216309871; 39161095700; 36066387900; 47962102500; 57202108143; 36063048400; 57195943060; 57208554686; 57215668136; 57215664066; 35254371300 | myheart@cnu.ac.kr; | KOREAN CIRCULATION JOURNAL | KOREAN CIRC J | 1738-5520 | 1738-5555 | 50 | 4 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS | 2020 | 3.243 | 46.1 | 0.22 | 2025-06-25 | 3 | 3 | Carotid artery stenosis; Carotid endarterectomy | EARLY OUTCOMES; ENDARTERECTOMY; MANAGEMENT; DISEASE; IMPACT | Carotid artery stenosis; Carotid endarterectomy | antihypertensive agent; antithrombocytic agent; Article; asymptomatic carotid stenosis; Bayesian network; carotid artery obstruction; carotid artery stenting; carotid endarterectomy; cerebrovascular accident; comparative study; follow up; heart infarction; human; meta analysis; patient safety; randomized controlled trial (topic); systematic review; therapy effect | English | 2020 | 2020-04 | 10.4070/kcj.2019.0125 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Interannual variations of spring drought-prone conditions over three subregions of East Asia and associated large-scale circulations | For proactive prevention of water shortage problems, it is important to understand the spatiotemporal variabilities of droughts and their development mechanisms. This study identified an interannual variation of spring drought-prone condition in each region of East Asia (EA)-northern, mid, and southern EA-for the period 1979-2015 by using the standardized precipitation evapotranspiration index (SPEI) and a hierarchical clustering analysis. According to our analyses, spring drought-prone condition in the northern EA region mainly depends on local surface heating and precipitation deficit due to adiabatic compression by a high-pressure anomaly over the region during the preceding winter to spring. The high-pressure anomaly was driven by an upper-level wave train propagating from the Europe related to a positive phase of the Arctic Oscillation. For drought-prone conditions in the mid and the southern EA regions, the local precipitation deficit caused by the negative moisture advection/convergence therein acts as a primary factor. During the preceding winter, the negative moisture advection/convergence anomalies both in mid and southern EA regions were induced by anomalous low-level cyclonic circulations over the western North Pacific related to the La Nina. In spring, however, the moisture condition in the southern EA region was affected by persistent La Nina while that in the mid-EA region was by the negative phase of North Pacific Oscillation. This gap makes the main location of the negative moisture advection/convergence anomalies just slightly different, but considerably alter the region exposed to the drought-prone condition. | Park, Chang-Kyun; Ho, Chang-Hoi; Park, Doo-Sun R.; Park, Tae-Won; Kim, Jinwon | Seoul Natl Univ, Sch Earth & Environm Sci, Seoul, South Korea; Kyungpook Natl Univ, Dept Earth Sci Educ, Daegu, South Korea; Chonnam Natl Univ, Dept Earth Sci Educ, Gwangju, South Korea; Natl Inst Meteorol Sci, Korea Meteorol Adm, Jeju, South Korea | ; Park, Doo-Sun/U-9448-2019; Park, Tae-Won/AAE-3559-2019; Ho, Chang-Hoi/H-8354-2015 | 56606491800; 7404653593; 37117659000; 55716995500; 57200530823 | hoch@cpl.snu.ac.kr; | THEORETICAL AND APPLIED CLIMATOLOGY | THEOR APPL CLIMATOL | 0177-798X | 1434-4483 | 142 | 3-4 | SCIE | METEOROLOGY & ATMOSPHERIC SCIENCES | 2020 | 3.179 | 46.3 | 0.62 | 2025-06-25 | 14 | 14 | Spring drought; East Asia; SPEI; Arctic Oscillation; El-Nino Southern Oscillation; North Pacific Oscillation | EXTREME DROUGHT; SOUTH CHINA; NORTH CHINA; EL-NINO; PRECIPITATION; OSCILLATION; PACIFIC; CLIMATE; ENSO; RAINFALL | Arctic Oscillation; East Asia; El-Niño Southern Oscillation; North Pacific Oscillation; SPEI; Spring drought | Far East; annual variation; Arctic Oscillation; cluster analysis; drought; El Nino-Southern Oscillation; evapotranspiration; hierarchical system; precipitation assessment; spring (season) | English | 2020 | 2020-11 | 10.1007/s00704-020-03371-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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